Researcher Profile and Settings

Researcher

• Name

  ROKUDAI Susumu

Affiliation

• Education and Research Support Center, Lecturer

Profile and Settings

• Name

  Susumu, Rokudai

Alternate Names

• Susumu Rokudai
• S Rokudai
• Rokudai S

Foreign language

• Use in presentation

  English

• Use in publication

  English

Affiliation

• Gunma University, Graduate School of Medicine Biosystem Medicine Oncology, Lecturer
• Gunma University, Graduate School of Medicine Biosystem Medicine Oncology, Lecturer

Affiliation

• Affiliation

  Graduate School of Medicine

Education

• 1994, 1998, The University of Tokyo, Faculty of Pharmaceutical Sciences
• 2000, 2003, The University of Tokyo, Pharmacology

Degree

• Ph.D., The University of Tokyo, 2003

Association Memberships

• JCA (The Japanese Cancer Association), 2001, 2024
• JAMTTC (The Japanese Association for Molecular Target Therapy of Cancer), 2013, 2024
• JCO (The Japan Society of Clinical Oncology), 2013, 2024
• AACR (American Association for Cancer Research), 2014, 2024
• The Molecular Biology Society of Japan, 2013, 2024
• The Pharmaceutical Society of Japan, 2018, 9999

Research Experience

• 2019, 9999, Gunma University,, Molecular Pharmacology and Oncology, Associate prof lecturer lv
• 2013, 2019, Gunma University,, Molecular Pharmacology and Oncology, Associate prof lecturer lv
• 2009, 2013, Columbia University,, Biological Sciences,, Research Associate, Assistant prof lv, United States
• 2003, 2009, National Cancer Center, Research Institute, Assistant prof lv
• 2001, 2003, The University of Tokyo, Department of Pharmacology

Research Activities

Research Areas

• Life sciences, Tumor biology

Research Interests

• Molecular Target Therapy of Cancer
• Cancer Biomarker
• p53, p53 related genes
• TME (Tumor Micro-Environment)

Published Papers

• Methods to Identify and Validate Therapeutic Targets against CAFs in Head and Neck Squamous Cell Carcinoma. (Reviews), Takahashi H, Rokudai S, Chikamatsu K., 2024, Immune Mediators in Cancer 2nd edition, Methods in Mol Biol., 1, 1, 1, Scientific journal
• High-Throughput RNA Interference Screen Targeting Synthetic-Lethal Gain-of-Function of Oncogenic Mutant TP53 in Triple-Negative Breast Cancer, Susumu Rokudai, 2024, Immune Mediators in Cancer 2nd edit, Methods in Mol Biol., 1, 1, 1, Scientific journal
• Confocal microscopic oxygen imaging of xenograft tumors using Ir(III) complexes as in vivo intravascular and intracellular probes., Yoshihara T, Tamura T, Shiozaki S, Li-Chieh Chou, Kakuchi R & Rokudai S, Aug. 2024, Scientific Reports, 14, 1, 18443, Scientific journal

  DOI
• AKT3 is a key regulator of head and neck squamous cell carcinoma., Takahashi H, Rokudai S, Kawabata-Iwakawa R, Sakakura K, Oyama T, Nishiyama M, Chikamatsu K, Jun. 2021, Cancer Science, 112, 6, 2325, 2334, Scientific journal

  DOI
• AKT3 is a novel regulator of cancer-associated fibroblasts in head and neck squamous cell carcinoma, Takahashi H, Rokudai S, Kawabata-Iwakawa R, Sakakura K, Oyama T, Nishiyama M, Chikamatsu K, Mar. 2021, Cancers (Basel), 13, 6, 1233, Scientific journal

  DOI
• Syntaxin binding proten 4 as a novel therapeutic target and an effective biomarker for better treatment selection in lung squamous cell carcinoma.(Review), Bilguun EO, Kaira K, Kawabata-Iwakawa R, Rokudai S, Shimizu K, Yokobori T, Oyama T, Shirabe K, Nishiyama M, 2020, Research Square

  DOI
• High-Throughput RNA Interference Screen Targeting Synthetic-Lethal Gain-of-Function of Oncogenic Mutant TP53 in Triple-Negative Breast Cance, Susumu Rokudai, 2020, Methods in Mol Biol. Springer Nature, 2108, 297, 303, Scientific journal
• STXBPの肺扁平上皮がんバイオマーカーの意義と分子標的治療の開発(Novel Biomarker and Development of Therapeutic Target for Squamous Cell Carcinoma), ;;;;;;;;, Sep. 2019, 78回, J
• STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis., Rokudai S; Lee Y; Otaka Y; Fujieda M; Owens DM; Christiano AM; Nishiyama M; Prives C, May 2018, Proc Natl Acad Sci USA, Plus Article, 115, 21, E4806, 4814, Scientific journal
• Mutant TP53 Modulates Metastasis of Triple Negative Breast Cancer through Adenosine A2b Receptor Signaling, Horigome E; Fujieda M; Handa T; Katayama A; Ito M; Ichihara A; Tanaka D; Gombodorj N; Yoshiyama S; Yamane A; Yamada K; Horiguchi J; Shinozuka K; Oyama T; Nishiyama M; Rokudai S, 2018, Oncotarget, 9, 34554, 34566, Scientific journal
• Elevated expression of Np63 in advanced esophageal squamous cell carcinoma, Yuji Kumakura; Susumu Rokudai; Misaki Iijima; Bolag Altan; Tomonori Yoshida; Halin Bao; Takehiko Yokobori; Makoto Sakai; Makoto Sohda; Tatsuya Miyazaki; Masahiko Nishiyama; Hiroyuki Kuwano, Nov. 2017, CANCER SCIENCE, 108, 11, 2149, 2155, Scientific journal

  DOI
• Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients, Tadashi Handa; Ayaka Katayama; Takehiko Yokobori; Arito Yamane; Jun Horiguchi; Reika Kawabata-Iwakawa; Susumu Rokudai; Pinjie Bao; Navchaa Gombodorj; Bolag Altan; Kyoichi Kaira; Takayuki Asao; Hiroyuki Kuwano; Masahiko Nishiyama; Tetsunari Oyama, Nov. 2017, JOURNAL OF SURGICAL ONCOLOGY, 116, 6, 706, 715, Scientific journal

  DOI
• STXBP4 Drives Tumor Growth and Is Associated with Poor Prognosis through PDGF Receptor Signaling in Lung Squamous Cell Carcinoma, Yukihiro Otaka; Susumu Rokudai; Kyoichi Kaira; Michiru Fujieda; Ikuko Horikoshi; Reika Iwakawa-Kawabata; Shinji Yoshiyama; Takehiko Yokobori; Yoichi Ohtaki; Kimihiro Shimizu; Tetsunari Oyama; Jun'ichi Tamura; Carol Prives; Masahiko Nishiyama, Jul. 2017, CLINICAL CANCER RESEARCH, 23, 13, 3442, 3452, Scientific journal

  DOI
• Inhibition of Ubiquitin-conjugating Enzyme E2 May Activate the Degradation of Hypoxia-inducible Factors and, thus, Overcome Cellular Resistance to Radiation in Colorectal Cancer, Navchaa Gombodorj; Takehiko Yokobori; Shinji Yoshiyama; Reika Kawabata-Iwakawa; Susumu Rokudai; Ikuko Horikoshi; Masahiko Nishiyama; Takashi Nakano, May 2017, ANTICANCER RESEARCH, 37, 5, 2425, 2436, Scientific journal

  DOI
• P63, A Master Regulator of Epithelial Cancer And Squamous Cell Carcinoma Driver., Rokudai S; Bilguun Erchem-Ochir; Masahiko Nishiyama, 2017, Anat Physiol (Reviews), 7(281), 2161-0940, 1000281
• Myeloid Sarcoma Arising in malignant Phyllodes Tumor: clonal relationships revealed by comparative genome-wide analyses., Arai H; Nobusawa S; Kawabata-Iwakawa R; Rokudai S; Higuchi T; Yamazaki T; Horiguchi J; Sano T; Kojima M; Nishiyama M; Yokoo H; Hirato J; Oyama T, 2017, British Journal of Haematology, 10, 1111
• APOBEC3B high expression status is associated with aggressive phenotype in Japanese breast cancers, Miki Tsuboi; Arito Yamane; Jun Horiguchi; Takehiko Yokobori; Reika Kawabata-Iwakawa; Shinji Yoshiyama; Susumu Rokudai; Hiroki Odawara; Hideaki Tokiniwa; Tetsunari Oyama; Izumi Takeyoshi; Masahiko Nishiyama, Sep. 2016, BREAST CANCER, 23, 5, 780, 788, Scientific journal

  DOI
• Nuclear PROX1 is Associated with Hypoxia-Inducible Factor 1 alpha Expression and Cancer Progression in Esophageal Squamous Cell Carcinoma, Takehiko Yokobori; Pinjie Bao; Minoru Fukuchi; Bolag Altan; Daigo Ozawa; Susumu Rokudai; Tuya Bai; Yuji Kumakura; Hiroaki Honjo; Keigo Hara; Makoto Sakai; Makoto Sohda; Tatsuya Miyazaki; Munenori Ide; Masahiko Nishiyama; Tetsunari Oyama; Hiroyuki Kuwano, Dec. 2015, ANNALS OF SURGICAL ONCOLOGY, 22, S1566, S1573, Scientific journal

  DOI
• Immunosuppressive activity of cancer-associated fibroblasts in head and neck squamous cell carcinoma, Hideyuki Takahashi; Koichi Sakakura; Reika Kawabata-Iwakawa; Susumu Rokudai; Minoru Toyoda; Masahiko Nishiyama; Kazuaki Chikamatsu, Nov. 2015, CANCER IMMUNOLOGY IMMUNOTHERAPY, 64, 11, 1407, 1417, Scientific journal

  DOI
• Immunosuppressive activity of cancer-associated fibroblasts in head and neck squamous cell carcinoma., Takahashi H; Sakakura K; Kawabata-Iwakawa R; Rokudai S; Toyoda M; Nishiyama M; Chikamatsu K, 2015, Cancer Immune Immunother., 64, 11, 1407, 17

  DOI
• MOZ increases p53 acetylation and premature senescence through its complex formation with PML, Susumu Rokudai; Oleg Laptenko; Suzzette M. Arnal; Yoichi Taya; Issay Kitabayashi; Carol Prives, Mar. 2013, Proceedings of the National Academy of Sciences of the United States of America, 110, 10, 3895, 3900, Scientific journal

  DOI
• Monocytic Leukemia Zinc Finger (MOZ) Interacts with p53 to Induce p21 Expression and Cell-cycle Arrest, Susumu Rokudai; Yukiko Aikawa; Yusuke Tagata; Nobuo Tsuchida; Yoichi Taya; Issay Kitabayashi, Jan. 2009, JOURNAL OF BIOLOGICAL CHEMISTRY, 284, 1, 237, 244, Scientific journal

  DOI
• Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis., Susumu Rokudai; Naoya Fujita; Osamu Kitahara; Yusuke Nakamura; Takashi Tsuruo, Dec. 2002, Molecular and Cellular Biology, 22, 24, 8695, 708, Scientific journal

  DOI
• Prevention of phosphatidylinositol 3'-kinase-Akt survival signaling pathway during topotecan-induced apoptosis., A Nakashio; N Fujita; S Rokudai; S Sato; T Tsuruo, 15 Sep. 2000, Cancer Research, 60, 18, 5303, 9, Scientific journal
• Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis., S Rokudai; N Fujita; Y Hashimoto; T Tsuruo, Feb. 2000, Journal of cellular physiology, 182, 2, 290, 6

  DOI
• Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases., N Fujita; A Nagahashi; K Nagashima; S Rokudai; T Tsuruo, 10 Sep. 1998, Oncogene, 17, 10, 1295, 304, Scientific journal

  DOI
• Features of prognosis, genetics and drug sensitivity of very elderly lung cancer patients., Ohtaki, Yoichi;Yamane, Arito;Shimizu, Kimihiro;Rokudai, Susumu;Nagashima, Toshiteru;Obayashi, Kai;Yamashita, Yoshinori;Taniyama, Kiyomi;Mitsudomi, Tetsuya;Yatabe, Yasushi;Takeyoshi, Izumi;Nishiyama, Masahiko, 2015, JOURNAL OF CLINICAL ONCOLOGY, 33, 15
• Immunosuppressive activity of cancer-associated fibroblasts in head and neck squamous cell carcinoma, Takahashi, Hideyuki;Sakakura, Koichi;Kawabata-Iwakawa, Reika;Rokudai, Susumu;Toyoda, Minoru;Nishiyama, Masahiko;Chikamatsu, Kazuaki, 2015, CANCER IMMUNOLOGY IMMUNOTHERAPY, 64, 11, 1407, 1417

  DOI
• Nuclear PROX1 is Associated with Hypoxia-Inducible Factor 1 alpha Expression and Cancer Progression in Esophageal Squamous Cell Carcinoma, Yokobori, Takehiko;Bao, Pinjie;Fukuchi, Minoru;Altan, Bolag;Ozawa, Daigo;Rokudai, Susumu;Bai, Tuya;Kumakura, Yuji;Honjo, Hiroaki;Hara, Keigo;Sakai, Makoto;Sohda, Makoto;Miyazaki, Tatsuya;Ide, Munenori;Nishiyama, Masahiko;Oyama, Tetsunari;Kuwano, Hiroyuki, 2015, ANNALS OF SURGICAL ONCOLOGY, 22, S1566, S1573

  DOI
• Stxbp4 suppresses APC/C mediated turnover of p63 and increases tumorigenicity and malignancy, Otaka, Yukihiro;Rokudai, Susumu;Kaira, Kyoichi;Shimizu, Kimihiro;Ito, Masashi;Ichihara, Ami;Kawabata, Reika;Yoshiyama, Shinji;Yamane, Arito;Asao, Takayuki;Prives, Carol;Nishiyama, Masahiko, 2015, CANCER RESEARCH, 75

  DOI
• APOBEC3B high expression status is associated with aggressive phenotype in Japanese breast cancers, Tsuboi, Miki;Yamane, Arito;Horiguchi, Jun;Yokobori, Takehiko;Kawabata-Iwakawa, Reika;Yoshiyama, Shinji;Rokudai, Susumu;Odawara, Hiroki;Tokiniwa, Hideaki;Oyama, Tetsunari;Takeyoshi, Izumi;Nishiyama, Masahiko, 2016, BREAST CANCER, 23, 5, 780, 788

  DOI
• Inhibition of Ubiquitin-conjugating Enzyme E2 May Activate the Degradation of Hypoxia-inducible Factors and, thus, Overcome Cellular Resistance to Radiation in Colorectal Cancer, Gombodorj, Navchaa;Yokobori, Takehiko;Yoshiyama, Shinji;Kawabata-Iwakawa, Reika;Rokudai, Susumu;Horikoshi, Ikuko;Nishiyama, Masahiko;Nakano, Takashi, 2017, ANTICANCER RESEARCH, 37, 5, 2425, 2436

  DOI
• STXBP4 Drives Tumor Growth and Is Associated with Poor Prognosis through PDGF Receptor Signaling in Lung Squamous Cell Carcinoma, Otaka, Yukihiro;Rokudai, Susumu;Kaira, Kyoichi;Fujieda, Michiru;Horikoshi, Ikuko;Iwakawa-Kawabata, Reika;Yoshiyama, Shinji;Yokobori, Takehiko;Ohtaki, Yoichi;Shimizu, Kimihiro;Oyama, Tetsunari;Tamura, Jun'ichi;Prives, Carol;Nishiyama, Masahiko, 2017, CLINICAL CANCER RESEARCH, 23, 13, 3442, 3452

  DOI
• Elevated expression of Np63 in advanced esophageal squamous cell carcinoma, Kumakura, Yuji;Rokudai, Susumu;Iijima, Misaki;Altan, Bolag;Yoshida, Tomonori;Bao, Halin;Yokobori, Takehiko;Sakai, Makoto;Sohda, Makoto;Miyazaki, Tatsuya;Nishiyama, Masahiko;Kuwano, Hiroyuki, 2017, CANCER SCIENCE, 108, 11, 2149, 2155

  DOI
• Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients, Handa, Tadashi;Katayama, Ayaka;Yokobori, Takehiko;Yamane, Arito;Horiguchi, Jun;Kawabata-Iwakawa, Reika;Rokudai, Susumu;Bao, Pinjie;Gombodorj, Navchaa;Altan, Bolag;Kaira, Kyoichi;Asao, Takayuki;Kuwano, Hiroyuki;Nishiyama, Masahiko;Oyama, Tetsunari, 2017, JOURNAL OF SURGICAL ONCOLOGY, 116, 6, 706, 715

  DOI
• Novel Biomarker for Therapeutic Target in Lung Squamous Cell Carcinoma, Rokudai, Susumu;Otaka, Yukihiro;Gombodorji, Navchaa;Horigome, Eisuke;Suzuki, Kazunari;Tanaka, Daiki;Erkhem-ochir, Bilguun;Atlan, Bolag;Kawabata, Reika;Yokobori, Takehiko;Shimizu, Kimihiro;Kuwano, Hiroyuki;Nishiyama, Masahiko, 2018, CANCER SCIENCE, 109, 224, 224
• Intra tumor heterogeneity involving malignancy in liver metastatic colorectal cancer, Kawabata, Reika;Turtoi, Andrei;Otaka, Yukihiro;Rokudai, Susumu;Yokobori, Takehiko;Costanza, Burnella;Nishiyama, Masahiko, 2018, CANCER SCIENCE, 109, 992, 992
• Myeloid sarcoma arising in malignant phyllodes tumour: clonal relationships revealed by comparative genome-wide analyses, Arai, Hideo;Nobusawa, Sumihito;Kawabata-Iwakawa, Reika;Rokudai, Susumu;Higuchi, Toru;Yamazaki, Tatsuya;Horiguchi, Jun;Sano, Takaaki;Kojima, Masaru;Nishiyama, Masahiko;Yokoo, Hideaki;Hirato, Junko;Oyama, Tetsunari, 2018, BRITISH JOURNAL OF HAEMATOLOGY, 181, 2, 255, 259

  DOI
• STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis, Rokudai, Susumu;Li, Yingchun;Otaka, Yukihiro;Fujieda, Michiru;Owens, David M.;Christiano, Angela M.;Nishiyama, Masahiko;Prives, Carol, 2018, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115, 21, E4806, E4814

  DOI
• Significance of aromatase-estrogen receptor axis in EGFR status of lung adenocarcinoma., Tanaka, Kazumi;Rokudai, Susumu;Shimizu, Kimihiro;Nakazawa, Seshiru;Obayashi, Kai;Kaira, Kyoichi;Oyama, Tetsunari;Shirabe, Ken;Mogi, Akira;Nishiyama, Masahiko;Kuwano, Hiroyuki, 2018, JOURNAL OF CLINICAL ONCOLOGY, 36, 15
• STXBP4 Regulates APC/C-Mediated p63 Turnover and is a Novel Biomarker in Lung Squamous Cell Carcinoma, Rokudai, Susumu;Tanaka, Daiki;Sugimoto, Akio;Suzuki, Kazunari;Horigome, Eisuke;Fujieda, Michiru;Khorolgaray, Enkhtuvshin;Erkem-Ocir, Bilguun;Bao, Halin;Navchaa, Gombodorji;Shimizu, Kimihiro;Oyama, Tetsunari;Nishiyama, Masahiko, 2018, CANCER SCIENCE, 109, 227, 227
• Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine, Bilguun, Erkhem-Ochir;Kaira, Kyoichi;Kawabata-Iwakawa, Reika;Rokudai, Susumu;Shimizu, Kimihiro;Yokobori, Takehiko;Oyama, Tetsunari;Shirabe, Ken;Nishiyama, Masahiko, 2020, BMC CANCER, 20, 1

  DOI
• KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs, Yan, Fangxue;Li, Jinyang;Milosevic, Jelena;Petroni, Ricardo;Liu, Suying;Shi, Zhennan;Yuan, Salina;Reynaga, Janice M.;Qi, Yuwei;Rico, Joshua;Yu, Sixiang;Liu, Yiman;Rokudai, Susumu;Palmisiano, Neil;Meyer, Sara E.;Sung, Pamela J.;Wan, Liling;Lan, Fei;Garcia, Benjamin A.;Stanger, Ben Z.;Sykes, David B.;Blanco, M. Andres, Mar. 2022, CANCER DISCOVERY, 12, 3, 792, 811, Scientific journal

  DOI
• Cancer. p53 Guardian of the Genome, Rokudai Susumu, 2017, The Kitakanto Medical Journal, 67, 1, 63, 64

  DOI
• Stxbp4によるp63依存的な癌悪性化機序, ;;;;;;;;, Oct. 2015, 74回, P
• 日本人原発性乳癌におけるAPOBEC3B mRNAの発現と内的・外的因子との検討, ;;;;;;;;;;;;;;;;;, Apr. 2016, 116回, OP
• 肺扁平上皮癌におけるSTXBPの発現と腫瘍悪性化、予後不良への影響, ;;;;;;;;;;;;, Oct. 2016, 75回, E
• 網羅的遺伝子発現解析およびshRNAライブラリー解析に基づくトリプルネガティブ乳がんに対する新規治療標的の同定, ;;;;;;;;;;;, Oct. 2016, 75回, P
• 癌関連線維芽細胞における治療標的分子としてのAkt3の可能性, ;;;;;, May 2017, 43, 2, 223
• 肺・食道扁平上皮癌におけるTP63とその周辺分子の発現についての検討, ;;;;;;;;;;;;;, Apr. 2017, 117回, CSS
• 肺腺癌におけるアロマターゼの意義と細胞増殖能への影響, ;;;;;;;;;;;;;;, Apr. 2017, 117回, PS
• 肺扁平上皮癌における新規分子標的の探索, ;;;;;;;;;;;;, Sep. 2017, 76回, P
• 転移性大腸がんの腫瘍内不均一性と悪性度に関わる因子の解析, ;;;;;;, Sep. 2017, 76回, P
• 肺扁平上皮癌の治療標的に関する新規バイオマーカー(Novel Biomarker for Therapeutic Target in Lung Squamous Cell Carcinoma), ;;;;;;;;;;;;;;, Oct. 2017, 55回, O25
• 難治性トリプルネガティブ乳癌に対するNGSによる新規治療標的の探索, ;;;;;;;;;;;;;;, Oct. 2017, 55回, P12
• 共焦点りん光寿命イメージング顕微鏡を用いた腫瘍の酸素化状態の高分解能イメージング, ;;;;;;;;, May 2018, 11, 2, 105
• 肺腺癌におけるアロマターゼの意義と細胞増殖能への影響, ;;;;;;;;;;;;;, Apr. 2018, 118回, 1169
• Syntaxin Binding Protein 4(Stxbp4)はΔNP63の安定化を介して肺扁平上皮癌の前癌病変形成に関わる, ;;;;;;;;;;;;, Apr. 2018, 118回, 2162
• 共焦点りん光イメージング顕微鏡を用いた腫瘍の酸素化状態の高分解能イメージング, ;;;;;;;;, Dec. 2018, 12, 1, 32
• STXBP4におけるp63制御機構の解明と肺扁平上皮癌における新規バイオマーカーの探索(STXBP4 Regulates APC/C-Mediated p63 Turnover and is a Novel Biomarker in Lung Squamous Cell Carcinoma), ;;;;;;;;;;;;, Sep. 2018, 77回, 183
• PLIM法を用いた腫瘍組織の高分解能酸素イメージング, ;;;;;;;;, May 2019, 12, 2, 112
• 肺扁平上皮がんにおける新規バイオマーカーと分子治療標的, ;;;;;;;;;;;;;, Oct. 2019, 57回, P89
• Immunosuppressive activity of cancer-associated fibroblasts in head and neck squamous cell carcinoma., Takahashi Hideyuki;Sakakura Koichi;Kawabata-Iwakawa Reika;Rokudai Susumu;Toyoda Minoru;Nishiyama Masahiko;Chikamatsu Kazuaki, Jul. 2015, Cancer immunology, immunotherapy : CII, 64, 11

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• Nuclear PROX1 is Associated with Hypoxia-Inducible Factor 1α Expression and Cancer Progression in Esophageal Squamous Cell Carcinoma., Yokobori Takehiko;Bao Pinjie;Fukuchi Minoru;Altan Bolag;Ozawa Daigo;Rokudai Susumu;Bai Tuya;Kumakura Yuji;Honjo Hiroaki;Hara Keigo;Sakai Makoto;Sohda Makoto;Miyazaki Tatsuya;Ide Munenori;Nishiyama Masahiko;Oyama Tetsunari;Kuwano Hiroyuki, Aug. 2015, Annals of surgical oncology, 22 Suppl 3

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• APOBEC3B high expression status is associated with aggressive phenotype in Japanese breast cancers., Tsuboi Miki;Yamane Arito;Horiguchi Jun;Yokobori Takehiko;Kawabata-Iwakawa Reika;Yoshiyama Shinji;Rokudai Susumu;Odawara Hiroki;Tokiniwa Hideaki;Oyama Tetsunari;Takeyoshi Izumi;Nishiyama Masahiko, Oct. 2015, Breast cancer (Tokyo, Japan), 23, 5

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• STXBP4 Drives Tumor Growth and Is Associated with Poor Prognosis through PDGF Receptor Signaling in Lung Squamous Cell Carcinoma., Otaka Yukihiro;Rokudai Susumu;Kaira Kyoichi;Fujieda Michiru;Horikoshi Ikuko;Iwakawa-Kawabata Reika;Yoshiyama Shinji;Yokobori Takehiko;Ohtaki Yoichi;Shimizu Kimihiro;Oyama Tetsunari;Tamura Jun'ichi;Prives Carol;Nishiyama Masahiko, Jan. 2017, Clinical cancer research : an official journal of the American Association for Cancer Research, 23, 13

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• Myeloid sarcoma arising in malignant phyllodes tumour: clonal relationships revealed by comparative genome-wide analyses., Arai Hideo;Nobusawa Sumihito;Kawabata-Iwakawa Reika;Rokudai Susumu;Higuchi Toru;Yamazaki Tatsuya;Horiguchi Jun;Sano Takaaki;Kojima Masaru;Nishiyama Masahiko;Yokoo Hideaki;Hirato Junko;Oyama Tetsunari, Feb. 2017, British journal of haematology, 181, 2

  DOI
• Inhibition of Ubiquitin-conjugating Enzyme E2 May Activate the Degradation of Hypoxia-inducible Factors and, thus, Overcome Cellular Resistance to Radiation in Colorectal Cancer., Gombodorj Navchaa;Yokobori Takehiko;Yoshiyama Shinji;Kawabata-Iwakawa Reika;Rokudai Susumu;Horikoshi Ikuko;Nishiyama Masahiko;Nakano Takashi, Anticancer research, 37, 5

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• Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients., Handa Tadashi;Katayama Ayaka;Yokobori Takehiko;Yamane Arito;Horiguchi Jun;Kawabata-Iwakawa Reika;Rokudai Susumu;Bao Pinjie;Gombodorj Navchaa;Altan Bolag;Kaira Kyoichi;Asao Takayuki;Kuwano Hiroyuki;Nishiyama Masahiko;Oyama Tetsunari, Jun. 2017, Journal of surgical oncology, 116, 6

  DOI
• Elevated expression of ΔNp63 in advanced esophageal squamous cell carcinoma., Kumakura Yuji;Rokudai Susumu;Iijima Misaki;Altan Bolag;Yoshida Tomonori;Bao Halin;Yokobori Takehiko;Sakai Makoto;Sohda Makoto;Miyazaki Tatsuya;Nishiyama Masahiko;Kuwano Hiroyuki, Oct. 2017, Cancer science, 108, 11

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• Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signaling., Horigome Eisuke;Fujieda Michiru;Handa Tadashi;Katayama Ayaka;Ito Masashi;Ichihara Ami;Tanaka Daiki;Gombodorj Navchaa;Yoshiyama Shinji;Yamane Arito;Yamada Keiichi;Horiguchi Jun;Shinozuka Kazuo;Oyama Tetsunari;Nishiyama Masahiko;Rokudai Susumu, Oct. 2018, Oncotarget, 9, 77

  DOI
• Carbonic anhydrase 9 expression is associated with poor prognosis, tumor proliferation, and radiosensitivity of thymic carcinomas., Ohtaki Yoichi;Shimizu Kimihiro;Kawabata-Iwakawa Reika;Gombodorj Navchaa;Altan Bolag;Rokudai Susumu;Yamane Arito;Kaira Kyoichi;Yokobori Takehiko;Nagashima Toshiteru;Obayashi Kai;Nakazawa Seshiru;Iijima Misaki;Kosaka Takayuki;Yajima Toshiki;Mogi Akira;Kuwano Hiroyuki;Shirabe Ken;Nishiyama Masahiko, Feb. 2019, Oncotarget, 10, 13

  DOI
• High-Throughput RNA Interference Screen Targeting Synthetic-Lethal Gain-of-Function of Oncogenic Mutant TP53 in Triple-Negative Breast Cancer., Rokudai Susumu, Methods in molecular biology (Clifton, N.J.), 2108

  DOI
• Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine., Bilguun Erkhem-Ochir;Kaira Kyoichi;Kawabata-Iwakawa Reika;Rokudai Susumu;Shimizu Kimihiro;Yokobori Takehiko;Oyama Tetsunari;Shirabe Ken;Nishiyama Masahiko, Sep. 2020, BMC cancer, 20, 1

  DOI
• The ion channel TRPM7 regulates zinc-depletion-induced MDMX degradation., Wang Herui;Li Bin;Asha Kulsum;Pangilinan Ryan L;Thuraisamy Asha;Chopra Harman;Rokudai Susumu;Yu Yong;Prives Carol L;Zhu Yan, Nov. 2021, The Journal of Biological Chemistry, 297, 5, 101292, Scientific journal

  DOI
• KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs., Yan Fangxue;Li Jinyang;Milosevic Jelena;Petroni Ricardo;Liu Suying;Shi Zhennan;Yuan Salina;Reynaga Janice M;Qi Yuwei;Rico Joshua;Yu Sixiang;Liu Yiman;Rokudai Susumu;Palmisiano Neil;Meyer Sara E;Sung Pamela J;Wan Liling;Lan Fei;Garcia Benjamin A;Stanger Ben Z;Sykes David B;Blanco M Andrés, Cancer discovery, 12, 3

  DOI

MISC

• 扁平上皮がんにおける新規p63結合分子STXBP4によるがん分子行的薬の探索, 六代範、中嶋理名、鈴木佑果、毛利彩華、調憲（共同研究者：藤枝みちる、小山徹也）, 2024, JAMTTC
• 肺腺癌におけるアロマターゼの細胞増殖能と転移能への影響, 中嶋理名、鈴木佑果、毛利彩華、調憲、六代範（共同研究者：田中和美、大瀧容一、中澤世知、尾林海、藤枝みちる、清水公裕、小山徹也）, 2024, JAMTTC
• P450 Aromatase gene(CYP19A1) is associated with tumor growth and metastasis in NSCLC., 大和田竜司、矢澤理麻、中嶋理名、藤枝みちる、田中和美、大瀧容一、中澤世知、大林海、解良恭一、小山徹也、清水公裕、調憲、六代範, 2023, JCA
• Syntaxin Binding Protein 4(Stxbp4)はΔNP63の安定化を介して肺扁平上皮癌の前癌病変形成に関わる, 飯島 岬; 六代 範; 茂木 晃; 清水 公裕; 矢島 俊樹; 高坂 貴行; 大瀧 容一; 渥實 潤; 尾林 海; 中澤 世識; 河谷 奈津子; 調 憲; 桑野 博行, Apr. 2018, 日本外科学会定期学術集会抄録集, 118回, 2162, 2162
• Novel Biomarker for Therapeutic Target in Lung Squamous Cell Carcinoma., Rokudai S; Otaka Y; Gombodorji N; Horigome E; Suzuki K; Tanaka D; Erkhem Ochir B; Atlan B; Kawabata R; Yokobori T; Shimizu K; Kuwano H; Nishiyama M, 2018, Cancer Science (JCA学会誌), 109, 224, 228
• 肺腺癌におけるアロマターゼの意義と細胞増殖能への影響, 田中 和美; 清水 公裕; 六代 範; 大瀧 容一; 渥實 潤; 中澤 世識; 尾林 海; 矢島 俊樹; 高坂 貴行; 河谷 菜津子; 小山 徹也; 茂木 晃; 西山 正彦; 桑野 博行, Apr. 2018, 日本外科学会定期学術集会抄録集, 118回, 1169, 1169
• Intra tumor heterogeneity involving malignancy in liver metastatic colorectal cancer., Kawabata R; Turtoi A; Otaka Y; Rokudai S; Yokobori T; Costanza B; Kuwano H; Nishiyama M, 2018, Cancer Science (JCA学会誌), 109, 992
• 肺扁平上皮癌における新規分子標的の探索, 六代 範; 大高 行博; ゴンボドジ・ナフチャ; 堀込 瑛介; 鈴木 一設; 田中 大輝; Erkhem-Ochir Bilguun; Atlan Bolag; 川端 麗香; 横堀 武彦; 清水 公裕; 桑野 博行; 西山 正彦, Sep. 2017, 日本癌学会総会記事, 76回, P, 1114
• 進行食道扁平上皮癌におけるΔNp63の高発現(Elevated expression of ΔNp63 in advanced esophageal squamous cell carcinoma), Kumakura Yuji; Rokudai Susumu; Iijima Misaki; Altan Bolag; Yoshida Tomonori; Bao Halin; Yokobori Takehiko; Sakai Makoto; Sohda Makoto; Miyazaki Tatsuya; Nishiyama Masahiko; Kuwano Hiroyuki, Nov. 2017, Cancer Science, 108, 11, 2149, 2155
• 肺腺癌におけるアロマターゼの意義と細胞増殖能への影響, 田中 和美; 清水 公裕; 六代 範; 長島 宗晃; 大瀧 容一; 中澤 世識; 尾林 海; 矢島 俊樹; 高坂 貴行; 東 陽子; 堀口 淳; 小山 徹也; 茂木 晃; 西山 正彦; 桑野 博行, Apr. 2017, 日本外科学会定期学術集会抄録集, 117回, PS, 147
• 肺・食道扁平上皮癌におけるTP63とその周辺分子の発現についての検討, 飯島 岬; 東 陽子; 中澤 世識; 尾林 海; 大瀧 容一; 永島 宗晃; 高坂 貴行; 矢島 俊樹; 清水 公裕; 茂木 晃; 熊倉 裕二; 桑野 博行; 大高 行博; 六代 範, Apr. 2017, 日本外科学会定期学術集会抄録集, 117回, CSS, 8
• 難治性トリプルネガティブ乳癌に対するNGSによる新規治療標的の探索, 堀込 瑛介; 六代 範; 半田 正; 片山 彩香; 堀越 郁子; 川端 麗香; 横堀 武彦; 鈴木 一設; 田中 大輝; Erkhem-Ohir Bilguun; Halin Bao; Bolag Altan; 堀口 淳; 小山 哲也; 西山 正彦, Oct. 2017, 日本癌治療学会学術集会抄録集, 55回, P12, 3
• 転移性大腸がんの腫瘍内不均一性と悪性度に関わる因子の解析, 川端 麗香; Turtoi Andrei; 大高 行博; 六代 範; 横堀 武彦; Costanza Burnella; 西山 正彦, Sep. 2017, 日本癌学会総会記事, 76回, P, 3049
• 肺扁平上皮癌におけるSTXBPの発現と腫瘍悪性化、予後不良への影響, 六代 範; 大高 行博; 解良 恭一; 伊藤 優志; 市原 愛美; 堀込 瑛介; 川端 麗香; 吉山 伸司; 横堀 武彦; 清水 公裕; 小山 徹也; プライベス・キャロル; 西山 正彦, Oct. 2016, 日本癌学会総会記事, 75回, E, 3028
• Identification of Caspase-14 as one of the new therapeutic targets for triple negative breast cancer patients using shRNA library and next generation sequence., Takehiko Yokobori; Tadashi Handa; Reika Kawabata; Arito Yamane; Shinji Yoshiyama; Ayaka Katayama; Susumu Rokudai; Tetsunari Oyama; Masahiko Nishiyama, May 2016, JOURNAL OF CLINICAL ONCOLOGY, 34, 15, 15s, Summary international conference

  DOI
• Discovery of novel accessible protiens for therapeutic targeting og hepatocellular carcinoma., Turtoi, A; Otaka Y; Rokudai S; Yokobori T; Costanza B; Oyama T; Kuwano H; Delwaide J; Delvenne P; Detry O; Castronovo V; Nishiyama M, 2016, Acta Gastro-Enterologica Belgica （学会誌）, 79, 1, O13
• 網羅的遺伝子発現解析およびshRNAライブラリー解析に基づくトリプルネガティブ乳がんに対する新規治療標的の同定, 川端 麗香; 半田 正; 横堀 武彦; 六代 範; 堀込 瑛介; 田中 大輝; 吉山 伸司; 山根 有人; 堀越 郁子; 片山 彩香; 小山 徹也; 西山 正彦, Oct. 2016, 日本癌学会総会記事, 75回, P, 1015
• 肺がんトランスレーショナル・リサーチ Stxbp4は肺扁平上皮癌の独立予後因子であり腫瘍形成に関与する, 六代 範; 大高 行博; 解良 恭一; 伊藤 優志; 市原 愛美; 川端 麗香; 吉山 伸司; 大瀧 容一; 横堀 武彦; 山根 有人; 清水 公裕; 浅尾 高行; Prives Carol; 西山 正彦, Sep. 2015, JCO, 50, 3, 1298, 1298
• Stxbp4 suppresses APC/C mediated turnover of p63 and increases tumorigenicity and malignancy., Otaka Y; Rokudai S; Kaira K; Shimizu K; Ito M; Ichihara A; Kawabata R; Yoshiyama S; Yamane A; Asao T; Prives C; Nishiyama M, 2015, Cancer Research (AACR学会誌), 75, 15, 2070
• 日本人原発性乳癌におけるAPOBEC3B mRNAの発現と内的・外的因子との検討, 坪井 美樹; 横堀 武彦; 川端 麗香; 山根 有人; 小田原 宏樹; 内田 紗弥香; 樋口 徹; 矢島 玲奈; 時庭 英彰; 佐藤 亜矢子; 藤井 孝明; 長岡 りん; 高他 大輔; 吉山 伸司; 六代 範; 小山 徹也; 西山 正彦; 堀口 淳, Apr. 2016, 日本外科学会定期学術集会抄録集, 116回, OP, 009
• 全生存・腫瘍特異的生存から解析した高齢者肺癌の特徴, 大瀧 容一; 清水 公裕; 永島 宗晃; 尾林 海; 山根 有人; 六代 範; 山下 芳典; 谷山 清己; 光冨 徹哉; 谷田部 恭; 竹吉 泉; 西山 正彦, Apr. 2015, 日本呼吸器外科学会雑誌, 29, 3, O48, 1
• 乳癌におけるAPOBEC3B遺伝子発現と病理学的aggressive phenotypeの検討, 坪井 美樹; 山根 有人; 六代 範; 吉山 伸司; 中村 彰男; 半田 正; 内田 紗弥香; 樋口 徹; 時庭 英彰; 佐藤 亜矢子; 長岡 りん; 高他 大輔; 小田原 宏樹; 西山 正彦; 小山 徹也; 堀口 淳; 竹吉 泉, Jul. 2015, 23回, 356, 356
• 卵巣 卵巣がんトランスレーショナル・リサーチ luciferase assayを用いた肉眼的に認識できない卵巣癌微小腹膜播種マウスモデルの確立, 樋口 珠美; 高橋 遼; 横堀 武彦; 六代 範; 金 泉; 包 品杰; 桑野 博行; 西山 正彦; 浅尾 高行, Sep. 2015, 日本癌治療学会誌, 50, 3, 131, 131
• Features of prognosis, genetics and drug sensitivity of very elderly lung cancer patients., Ohtaki Y; Yamane A; Shimizu K; Rokudai S; Nagashima T; Obayashi K; Yamashita Y; Taniyama K; Mitsudomi T; Yatabe Y; Takeyoshi I; Nishiyama M, 2015, Journal of Clinical Oncology (ASCO学会誌), 31, 15, e20540
• APOBEC3B expression and pathological aggressive phenotype in breast cancer, 坪井 美樹; 山根 有人; 六代 範; 大高 行博; 吉山 伸司; 中村 彰男; Gombodorj Navchaa; 半田 正; 堀口 淳; 小山 徹也; 竹吉 泉; 西山 正彦, Sep. 2014, JCA, P3325
• Quantitative efficacy models and toxicity prediction for advanced gastric cancer patients on weekly paclitaxel therapy., 大高 行博; 山根 有人; Navchaa Gombodorj; 坪井 美樹; 吉山 伸司; 六代 範; 中村 彰男; 西山 正彦, 2014, P3397
• 進行再発胃癌に対するweekly paclitaxel療法の効果毒性予測 ゲノム薬理学的検討, 大高 行博; 山根 有人; Gombodori Navchaa; 半田 正; 吉山 伸司; 六代 範; 中村 彰男; 西山 正彦, Jun. 2014, 49, 3, 1291, 1291
• 全生存・腫瘍特異的生存から解析した高齢者肺癌の特徴, 大滝 容一; 清水 公裕; 永島 宗晃; 尾林 海; 山根 有人; 六代 範; 山下 芳典; 谷山 清己; 光冨 徹哉; 谷田部 恭; 竹吉 泉; 西山 正彦, Oct. 2014, 日本臨床外科学会雑誌, 75, 増刊, 375, 375
• Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription, X. L. Li; Y. Arai; H. Harada; Y. Shima; H. Yoshida; S. Rokudai; Y. Aikawa; A. Kimura; I. Kitabayashi, 08 Nov. 2007, Oncogene, 26, 51, 7231, 7239

  DOI

Books etc

• High-Throughput RNA Interference Screen Targeting Synthetic-Lethal Gain-of-Function of Oncogenic Mutant TP53 in Triple-Negative Breast Cancer., Single work, Rokudai S, Rokudai S, Springer Nature, 2020, Scholarly book
• Cancer Research and p53 world., KITAKANTO MEDICAL JOURNAL, 2017
• タンパク質科学イラストレイテッド, 2005, ISBN: 9784897064925

Presentations

• 肺腺癌におけるアロマターゼの細胞増殖能と、転移能への影響, 中嶋理名、鈴木佑果、毛利彩華、六代範、調憲（共同研究者：田中和実、大瀧容一、中澤世識、尾林海、藤枝みちる、清水公裕、小山徹也）, 第28回 日本がん分子標的治療学会学術集会, Jun. 2024, Jun. 2024, Japanese, Japan, International conference
• 扁平上皮がんにおける新規p63結合分子STXBP4によるがん分子行的薬の探索, 六代範、中嶋理名、鈴木佑果、毛利彩華、調憲（共同研究者：田中和実、藤枝みちる、小山徹也）, 第26回 日本がん分子標的治療学会学術集会, Jun. 2024, Jun. 2024, Japanese, Japan, International conference
• 肺腺癌におけるアロマターゼの意義と細胞増殖能への影響, 大和田 竜司、矢澤理麻、中嶋理名、調憲、六代範（共同研究者：田中和実、藤枝みちる、小山徹也）, 第26回 日本がん分子標的治療学会学術集会, Jun. 2022, Jun. 2022, Japanese, Japan, International conference
• 肺腺癌におけるアロマターゼの意義と細胞増殖能への影響, 大和田 竜司、矢澤理麻、中嶋理名、六代範、調憲（共同研究者：田中和実、藤枝みちる、小山徹也）, 第81回 日本癌学会学術集会, Sep. 2022, Sep. 2022, Japanese, Japan, International conference
• 肺腺癌におけるアロマターゼの意義と細胞増殖能への影響, 第118回 日本外科学会定期学術集会, 2018
• Aromatase-estrogen receptor axis in EGFR status on lung adenocarcinoma., Anti-Ccancer Treatment Japan., 2018
• Significance of aromatase-estrogen receptor axis in EGFR status of lung adenocarcinoma., ASCO, 2018
• Significance of aromatase-estrogen receptor axis in EGFR status of lung adenocarcinoma., ASCO, 2018
• Aromatase-estrogen receptor axis in EGFR status on lung adenocarcinoma., Anti-Ccancer Treatment Japan., 2018
• Syntaxin Binding Protein 4 (Stxbp4)はDNp63の安定化を介して肺扁平上皮癌の前癌病変形成に関わる, 第118回 日本外科学会定期学術集会, 2018
• 扁平上皮癌における新規p63結合分子STXBP4による腫瘍悪性化とがん分子標的薬の探索（WS講演）, 第22回 日本がん分子標的治療学会, 2018
• 共焦点りん光寿命イメージング顕微鏡を用いた腫瘍の酸素化状態の高分解能イメージング, 日本分子イメージング学会, 2018
• Emission lifetime imaging of living cells and tissues using a phosphorescent Iridium(III) complex and a confocal lifetime imaging microscopy., International Symposium of Gunma University Medical Innovation (GUMI), 2017
• 難治性トリプルネガティブ乳癌に対するNGSによる新規治療標的の探索, 55th JSCO （第55回 日本癌治療学会）, 2017
• Emission lifetime imaging of living cells and tissues using a phosphorescent Iridium(III) complex and a confocal lifetime imaging microscopy., International Symposium of Gunma University Medical Innovation (GUMI), 2017
• Novel Biomarker for therapeutic target in Lung Squamous Cell Carcinoma., 76th JCA （第76回 日本癌学会）, 2017
• Intra tumor heterogeneity involving malignancy in liver metastatic colorectal cancer., 76th JCA （第76回 日本癌学会）, 2017
• Novel Biomarker for therapeutic target in Lung Squamous Cell Carcinoma. WS講演, 55th JSCO(第55回 日本癌治療学会）, 2017
• Novel Biomarker for therapeutic target in Lung Squamous Cell Carcinoma. WS講演, 55th JSCO(第55回 日本癌治療学会）, 2017
• Intra tumor heterogeneity involving malignancy in liver metastatic colorectal cancer., 76th JCA （第76回 日本癌学会）, 2017
• Synthesis and biological evaluation of cytotoxic cyclic pentapeptide against triple negative breast cancer cell lines., International Symposium of Gunma University Medical Innovation (GUMI), 2017
• Novel Biomarker for therapeutic target in Lung Squamous Cell Carcinoma., 76th JCA （第76回 日本癌学会）, 2017
• 肺・食道扁平上皮癌におけるTP63とその周辺分子の発現検討, 第117回 日本外科学会定期学術集会, 2017
• 肺腺癌におけるアロマターゼ」の意義と細胞増殖能への影響, 第117回 日本外科学会定期学術集会, 2017
• 癌関連線維芽細胞における治療標的分子としてのAkt3の可能性, 第41回 日本頭頸部外科学会, 2017
• Synthesis and biological evaluation of cytotoxic cyclic pentapeptide against triple negative breast cancer cell lines., International Symposium of Gunma University Medical Innovation (GUMI), 2017
• Novel Biomarker for Therapeutic Target in Lung squamous cell carcinoma.（英語WS講演）, 54th JSCO（第54回 日本癌治療学会）, 2016
• Two Dimensional Intracellular and in vivo Oxygen Sensing by Using a Gated ICCD Camera., International Conference on Advanced Micro-Device Engineering., 2016
• Novel Biomarker for Therapeutic Target in Lung squamous cell carcinoma.（英語WS講演）, 75th JCA（第75回 日本癌学会）, 2016
• Two Dimensional Intracellular and in vivo Oxygen Sensing by Using a Gated ICCD Camera., International Symposium of Gunma University Medical Innovation., 2016
• Discovery of Novel Accessible Proteins for Therapeutic Targeting of Hepatocellular Carcinoma., International Medical Innovation Forum, 2016
• Identification of Caspase-14 as one of the therapeutic targets for triple negative breast cancer patients using shRNA library and next generation sequence., ASCO, 2016
• Nobel Biomarker for Therapeutic Target in Lung Squamous Cell Carcinoma., International Medical Innovation Forum, 2016
• Identification of Caspase-14 as one of the therapeutic targets for triple negative breast cancer patients using shRNA library and next generation sequence., ASCO, 2016
• Discovery of Novel Accessible Proteins for Therapeutic Targeting of Hepatocellular Carcinoma., International Medical Innovation Forum, 2016
• Nobel Biomarker for Therapeutic Target in Lung Squamous Cell Carcinoma., International Medical Innovation Forum, 2016
• Two Dimensional Intracellular and in vivo Oxygen Sensing by Using a Gated ICCD Camera., International Symposium of Gunma University Medical Innovation., 2016
• Two Dimensional Intracellular and in vivo Oxygen Sensing by Using a Gated ICCD Camera., International Conference on Advanced Micro-Device Engineering., 2016
• Novel Biomarker for Therapeutic Target in Lung squamous cell carcinoma.（英語WS講演）, 75th JCA（第75回 日本癌学会）, 2016
• Novel Biomarker for Therapeutic Target in Lung squamous cell carcinoma.（英語WS講演）, 54th JSCO（第54回 日本癌治療学会）, 2016
• Discovery of Novel Accessible Proteins for Targeted Therapies in Human Hepatocellular Carcinoma.（英語WS講演）, 54th JSCO （第54回 日本癌治療学会）, 2016
• Discovery of Novel Accessible Proteins for Targeted Therapies in Human Hepatocellular Carcinoma.（英語WS講演）, 54th JSCO （第54回 日本癌治療学会）, 2016
• 肺扁平上皮癌における新規p63結合分子Syntaxinの発現と腫瘍悪性化と癌分子標的薬の探索（WS講演）, 第20回 日本がん分子標的治療学会, 2016
• 難治性トリプルネガティブ乳癌に対する次世代型シークエンサーによる新規治療標的の探索, 第20回 日本がん分子標的治療学会, 2016
• Features of prognosis, genetics and drug sensitivity of very elderly lung cancer patients., ASCO, 2015
• Stxbp4 suppresses APC/C mediated turnover of P63 and increases tumorigenicity and malignancy., AACR, 2015
• Luciferase assayを用いた肉眼的に認識できない卵巣癌微小腹膜播種マウスモデルの確立, 第53回 日本癌治療学会学術集会, 2015
• RNA-sequencing data analysis suggests that immunotherapy might be a potent treatment option in elderly non-small cell lung cancer patients., ESMO Asia Congress, 2015
• Features of prognosis, genetics and drug sensitivity of very elderly lung cancer patients., ASCO, 2015
• Stxbp4 suppresses APC/C mediated turnover of P63 and increases tumorigenicity and malignancy., AACR, 2015
• RNA-sequencing data analysis suggests that immunotherapy might be a potent treatment option in elderly non-small cell lung cancer patients., ESMO Asia Congress, 2015
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International p53/p63/p73 Workshop, 2013
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., 72nd JCA (第72回 日本癌学会), 2013
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International p53/p63/p73 Workshop, 2013
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., 72nd JCA (第72回 日本癌学会), 2013
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International MDM2 Workshop, 2012
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., Cold Spring Harbor Meeting, Mechanisms & Models of Cancer, 2012
• Regulation and Interactions of the p53 Family (Keynote Speech), Cold Spring Harbor Meeting., 2012
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International MDM2 Workshop, 2012
• Regulation and Interactions of the p53 Family (Keynote Speech), Cold Spring Harbor Meeting., 2012
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., Cold Spring Harbor Meeting, Mechanisms & Models of Cancer, 2012
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International p53 Workshop, 2011
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International p53 Workshop, 2011
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International p53 Workshop., 2010
• APC/C plays a role in ubiquitin-mediated turnover of DNp63a., International p53 Workshop., 2010
• MOZ is involved in p53-mediated p21 expression and cell cycle arrest., International p53 Workshop, 2006
• MOZ is involved in p53-mediated p21 expression and cell cycle arrest., International p53 Workshop, 2006
• MOZ is involved in p53-mediated p21 expression and cell cycle arrest., Cold Spring Harbor, Transcription., 2005
• MOZ is involved in p53-mediated p21 expression and cell cycle arrest., Cold Spring Harbor, Transcription., 2005

Industrial Property Rights

• Patent right, Method for manufacturing peripheral nerve cells., Nishiyama M, Rokudai S, Yoshiyama S, Takahashi H., 2020, US Patent App 16/335.889, US Patent App 16/335.889
• Patent right, 特願2016-207211, 2016, 2016

Awards

• Japan society, Japan
• 2013
• 2009

Research Grants & Projects

• Susumu Rokudai
  2019, 2021

Educational Activities

Teaching Experience

• 2014, 2018, Postgraduate courses, Japan

Social Contribution

Social Contribution

• 高崎高校病院実習（文部科学省スーパーサイエンスプログラム事業）, 2016　(Target:　High school students)
• 高崎高校病院実習（文部科学省スーパーサイエンスプログラム事業）, 2018　(Target:　High school students)
• 高崎高校病院実習（文部科学省スーパーサイエンスプログラム事業）, 2019　(Target:　High school students)
• 高崎高校病院実習（文部科学省スーパーサイエンスプログラム事業）, 2020　(Target:　High school students)
• 高崎高校病院実習（文部科学省スーパーサイエンスプログラム事業）, 2017　(Target:　High school students)

Academic Contribution

• 日本癌学会（評議員会）, Academic society etc, JCA, 2021, 9999
• 日本がん分子標的治療学会（評議員会）, Academic society etc, 2018, 9999
• 日本薬学会（関東支部幹事会）, Academic society etc, 2025, 9999
• 北関東医学会（評議員会）, Academic society etc, 2013, 9999

Media Coverage

• 肺がん、悪性化遺伝子を発見　--群大など　発生・進行の仕組みを解明, Myself, 22 May 2018, Paper
• 肺がん悪性化の仕組み一端解明 --診断法や新薬開発期待, Myself, 04 Jun. 2018, Paper
• 肺がんにおける新たな悪性化遺伝子を発見し、がん悪性化の仕組みを解明, Myself, 21 May 2018, Internet
• 日本・ベルギー友好150周年記念　群馬大、国際シンポジウムを開催　 地域医療イノベーションR&D人材養成拠点, Other than myself, 26 Feb. 2016, PR
• 地域オープンイノベーションR&D人材養成国際シンポ・未来先端研究機構国際シンポを開催（群馬大）, Other than myself, 09 Mar. 2015, PR
• 未来医療研究人材養成拠点形成事業　群馬大、国際シンポジウムを開催, Other than myself, 04 Apr. 2014, PR
• 医療研究用ロボ開発―菌培養作業支援、来年内に製品化へ, Other than myself, 16 Dec. 2015, Paper
• 医療関連ロボ参入-溶液サンプル自動製作、遠隔操作バイオ・研究所向け, Other than myself, 01 Dec. 2015, Paper