Researcher Profile and Settings

Researcher

• Name

  KURUSHIMA Jun

Affiliation

• Laboratory of Bacterial Drug Resistance, Associate Professor

Profile and Settings

• Name

  Kurushima, Jun

Alternate Names

• Jun Kurushima

Foreign language

• Use in presentation

  English

• Use in publication

  English

Affiliation

• Gunma University, Graduate School of Medicine Laboratory of Bacterial Drug Resistance

Affiliation

• Affiliation

  Graduate School of Medicine

Education

• Apr. 2003, Mar. 2007, Kitasato University, School of Science
• Apr. 2007, Mar. 2009, Kitasato University, Ms. program, Graduate School of Infection Control Sciences
• Apr. 2009, Mar. 2012, Kitasato University, Ph.D. program, Graduate School of Infection Control Sciences

Degree

• Ph.D.
• Ph.D., Kitasato University

Research Experience

• Feb. 2020, Apr. 2021, Gunma University, Graduate School of Medicine Bacteriology, Research associate, Assistant prof lv
• Feb. 2017, Jan. 2020, University of Lausanne, Department of Fundamental Microbiology, Faculty of Biology and Medicine, Postdoctoral Fellow, Assistant prof lv
• Apr. 2012, Jan. 2017, Gunma University, Graduate School of Medicine Bacteriology, Research Associate, Assistant prof lv
• Apr. 2011, Mar. 2012, JSPS Reseach Fellow (DC2)
• May 2021, 9999, Gunma University, Graduate School of Medicine, Assistant Professor
• May 2021, Mar. 2023, Gunma University, Graduate School of Medicine Bacteriology, Associate prof lecturer lv
• Apr. 2021, 9999, Gunma Prefectural College of Health Sciences, Lecturer

Research Activities

Research Areas

• Life sciences, Bacteriology
• Life sciences, Systems genomics
• Life sciences, Infectious disease
• Life sciences, Genetics
• Life sciences, Hygiene and public health (laboratory)
• Life sciences, Molecular biology

Research Interests

• Enterococci
• Pneumococcus

Research Themes

• Functional Analyses of Enterococcal Bacteriocin, Enterococcus faecalis, Bacteriocin, Domestic Collaboration, 2012, -, Bacteriology (including Mycology), Grant-in-Aid for Scientific Research

Published Papers

• Elucidation of host diversity of the VanD-carrying genomic islands in enterococci and anaerobes., Yusuke Hashimoto, Junzo Hisatsune, Masato Suzuki, Jun Kurushima, Takahiro Nomura, Hidetada Hirakawa, Naoko Kojima, Yuichi Ono, Yutaka Hasegawa, Koichi Tanimoto, Motoyuki Sugai, Haruyoshi Tomita, Mar. 2022, JAC-antimicrobial resistance
• Inactivation of GalU leads to a cell wall-associated polysaccharide defect that reduces the susceptibility of Enterococcus faecalis to bacteriolytic agents., Jun Kurushima, Haruyoshi Tomita, 11 Mar. 2021, Applied and Environtal Microbiolgy, 87, 7, e02875-20, Scientific journal

  DOI
• Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration events , Jun Kurushima, Nathalie Campo, Renske van Raaphorst, Guillaume Cerckel, Patrice Polard, Jan-Willem Veening, 23 Sep. 2020, eLife, 8, e58771, Scientific journal

  DOI
• Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli , Hidetada Hirakawa, Kazutomo Suzue, Ayako Takita, Chikako Awazu, Jun Kurushima, Haruyoshi Tomita, 23 Sep. 2020, Scientific Reports, 10, e15173, Scientific journal

  DOI
• Progress Overview of Bacterial Two-Component Regulatory Systems as Potential Targets for Antimicrobial Chemotherapy., Hirakawa Hidetada;Kurushima Jun;Hashimoto Yusuke;Tomita Haruyoshi, 23 Sep. 2020, Antibiotics (Basel, Switzerland), 9, 10

  DOI
• Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli, Hirakawa, Hidetada;Suzue, Kazutomo;Takita, Ayako;Awazu, Chikako;Kurushima, Jun;Tomita, Haruyoshi, 2020, SCIENTIFIC REPORTS, 10, 1

  DOI
• Three New Integration Vectors and Fluorescent Proteins for Use in the Opportunistic Human Pathogen Streptococcus pneumoniae., Lance E Keller; Anne-Stéphanie Rueff; Jun Kurushima; Jan-Willem Veening, 22 May 2019, Genes, 10, 5, 394, 394, Scientific journal

  DOI
• Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan., Hashimoto Yusuke;Kurushima Jun;Nomura Takahiro;Tanimoto Koichi;Tamai Kiyoko;Yanagisawa Hideji;Shirabe Komei;Ike Yasuyoshi;Tomita Haruyoshi, 13 Dec. 2018, BMC microbiology, 18, 1

  DOI
• New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species., Takahiro Nomura; Yusuke Hashimoto; Jun Kurushima; Hidetada Hirakawa; Koichi Tanimoto; Bo Zheng; Genjie Ruan; Feng Xue; Jian Liu; Junzo Hisatsune; Motoyuki Sugai; Haruyoshi Tomita, Feb. 2018, Journal of microbiological methods, 145, 69, 72, Scientific journal

  DOI
• 食肉由来の腸球菌におけるバシトラシン耐性についての研究, ;;;;;, Feb. 2018, 73, 1, 142
• 鶏肉検体からのESBL,AmpC産生腸内細菌科細菌の分離と解析, ;;;;, Feb. 2018, 73, 1, 149
• New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species., Nomura Takahiro;Hashimoto Yusuke;Kurushima Jun;Hirakawa Hidetada;Tanimoto Koichi;Zheng Bo;Ruan Genjie;Xue Feng;Liu Jian;Hisatsune Junzo;Sugai Motoyuki;Tomita Haruyoshi, 05 Jan. 2018, Journal of microbiological methods, 145

  DOI
• Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan., Yusuke Hashimoto; Jun Kurushima; Takahiro Nomura; Koichi Tanimoto; Kiyoko Tamai; Hideji Yanagisawa; Komei Shirabe; Yasuyoshi Ike; Haruyoshi Tomita, 13 Dec. 2018, BMC microbiology, 18, 1, 213, 213, Scientific journal

  DOI
• New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species, Nomura, Takahiro;Hashimoto, Yusuke;Kurushima, Jun;Hirakawa, Hidetada;Tanimoto, Koichi;Zheng, Bo;Ruan, Genjie;Xue, Feng;Liu, Jian;Hisatsune, Junzo;Sugai, Motoyuki;Tomita, Haruyoshi, 2018, JOURNAL OF MICROBIOLOGICAL METHODS, 145, 69, 72

  DOI
• Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan, Hashimoto, Yusuke;Kurushima, Jun;Nomura, Takahiro;Tanimoto, Koichi;Tamai, Kiyoko;Yanagisawa, Hideji;Shirabe, Komei;Ike, Yasuyoshi;Tomita, Haruyoshi, 2018, BMC MICROBIOLOGY, 18

  DOI
• VanB型バンコマイシン耐性遺伝子群を保持したバンコマイシン感受性腸球菌に関する研究, ;;;;, Feb. 2017, 72, 1, 138
• 鶏肉由来リネゾリド低度耐性腸球菌株の解析, ;;;;, Feb. 2017, 72, 1, 140
• 鶏肉からのESBL、AmpC産生腸内細菌科細菌の分離と解析, ;;;;;, Feb. 2017, 72, 1, 141
• 食肉由来腸球菌のバシトラシン耐性についての研究, ;;;;, Feb. 2017, 72, 1, 142
• Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains., Kurushima Jun;Ike Yasuyoshi;Tomita Haruyoshi, 11 Aug. 2016, Journal of bacteriology, 198, 17

  DOI
• Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains., Jun Kurushima; Yasuyoshi Ike; Haruyoshi Tomita, 01 Sep. 2016, Journal of bacteriology, 198, 17, 2379, 90, Scientific journal

  DOI
• 実験動物マウスの細菌感染症フロントライン　腸管病原性大腸菌モデルとしてのCitrobacter rodentium感染症(Front-line of Bacterial Infectious Diseases of Mice　Citrobacter rodentium infection as model of human A/E pathogens), 久留島 潤, Feb. 2016, 71, 1, 39
• 低濃度VanB型バンコマイシン耐性を持つ腸球菌の臨床単離物の分析(Analysis of the clinical enterococcal isolates with low-level VanB-type vancomycin resistance), ;;;, Feb. 2016, 71, 1, 143
• 【グローバル化時代の耐性菌感染症】バンコマイシン耐性腸球菌, ;;;;;, Jan. 2016, 60, 1, 68
• Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains, Kurushima, Jun;Ike, Yasuyoshi;Tomita, Haruyoshi, 2016, JOURNAL OF BACTERIOLOGY, 198, 17, 2379, 2390

  DOI
• 日和見病原菌Enterococcus faecalisのプラスミドにコードされる溶菌酵素Bac41の作用機構, ;, Dec. 2015, 88回・38回, [2P0489]
• The Bordetella Secreted Regulator BspR Is Translocated into the Nucleus of Host Cells via Its N-Terminal Moiety: Evaluation of Bacterial Effector Translocation by the Escherichia coli Type III Secretion System., Akio Abe; Ryutaro Nishimura; Naomichi Tanaka; Jun Kurushima; Asaomi Kuwae, 06 Aug. 2015, PloS one, 10, 8, e0135140, Scientific journal

  DOI
• Bacteriocin Protein BacL(1) of Enterococcus faecalis Targets Cell Division Loci and Specifically Recognizes L-Ala(2)-Cross-Bridged Peptidoglycan, Kurushima, Jun;Nakane, Daisuke;Nishizaka, Takayuki;Tomita, Haruyoshi, 2015, JOURNAL OF BACTERIOLOGY, 197, 2, 286, 295

  DOI
• Bacteriocin protein BacL1 of Enterococcus faecalis targets cell division loci and specifically recognizes L-Ala2-cross-bridged peptidoglycan., Jun Kurushima; Daisuke Nakane; Takayuki Nishizaka; Haruyoshi Tomita, Jan. 2015, Journal of bacteriology, 197, 2, 286, 95, Scientific journal

  DOI
• Bacteriocin protein BacL1 of Enterococcus faecalis targets cell division loci and specifically recognizes L-Ala2-cross-bridged peptidoglycan., Kurushima Jun;Nakane Daisuke;Nishizaka Takayuki;Tomita Haruyoshi, 03 Nov. 2014, Journal of bacteriology, 197, 2

  DOI
• Bacteriocin protein BacL1 of Enterococcus faecalis is a peptidoglycan D-isoglutamyl-L-lysine endopeptidase., Jun Kurushima; Ikue Hayashi; Motoyuki Sugai; Haruyoshi Tomita, 27 Dec. 2013, The Journal of biological chemistry, 288, 52, 36915, 25, Scientific journal

  DOI
• The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica., Jun Kurushima; Asaomi Kuwae; Akio Abe, 11 Jun. 2012, PloS one, 7, 6, e38925, Scientific journal

  DOI
• Iron starvation regulates the type III secretion system in Bordetella bronchiseptica., Jun Kurushima; Asaomi Kuwae; Akio Abe, Jun. 2012, Microbiology and immunology, 56, 6, 356, 62, Scientific journal

  DOI
• Btc22 chaperone is required for secretion and stability of the type III secreted protein Bsp22 in Bordetella bronchiseptica., Jun Kurushima; Asaomi Kuwae; Akio Abe, Jun. 2012, FEMS microbiology letters, 331, 2, 144, 51, Scientific journal

  DOI
• EspJ effector in enterohemorrhagic E. coli translocates into host mitochondria via an atypical mitochondrial targeting signal., Jun Kurushima; Takeshi Nagai; Kanna Nagamatsu; Akio Abe, Jul. 2010, Microbiology and immunology, 54, 7, 371, 9, Scientific journal

  DOI
• Elucidation of host diversity of the VanD-carrying genomic islands in enterococci and anaerobes., Yusuke Hashimoto; Junzo Hisatsune; Masato Suzuki; Jun Kurushima; Takahiro Nomura; Hidetada Hirakawa; Naoko Kojima; Yuichi Ono; Yutaka Hasegawa; Koichi Tanimoto; Motoyuki Sugai; Haruyoshi Tomita, Mar. 2022, JAC-antimicrobial resistance, 4, 1, dlab189, Scientific journal

  DOI
• Inactivation of GalU Leads to a Cell Wall-Associated Polysaccharide Defect That Reduces the Susceptibility of Enterococcus faecalis to Bacteriolytic Agents., Jun Kurushima; Haruyoshi Tomita, 11 Mar. 2021, Applied and environmental microbiology, 87, 7, Scientific journal

  DOI
• Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli., Hidetada Hirakawa; Kazutomo Suzue; Ayako Takita; Chikako Awazu; Jun Kurushima; Haruyoshi Tomita, 23 Sep. 2020, Scientific reports, 10, 1, 15173, 15173, Scientific journal

  DOI
• Progress Overview of Bacterial Two-Component Regulatory Systems as Potential Targets for Antimicrobial Chemotherapy., Hidetada Hirakawa; Jun Kurushima; Yusuke Hashimoto; Haruyoshi Tomita, 23 Sep. 2020, Antibiotics (Basel, Switzerland), 9, 10, 635, 635, Scientific journal

  DOI
• Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration events., Jun Kurushima; Nathalie Campo; Renske van Raaphorst; Guillaume Cerckel; Patrice Polard; Jan-Willem Veening, 23 Sep. 2020, eLife, 9, Scientific journal

  DOI
• Bacteriocin Protein BacL(1) of Enterococcus faecalis Is a Peptidoglycan D-Isoglutamyl-L-lysine Endopeptidase, Kurushima, Jun;Hayashi, Ikue;Sugai, Motoyuki;Tomita, Haruyoshi, 2013, JOURNAL OF BIOLOGICAL CHEMISTRY, 288, 52, 36915, 36925

  DOI
• Progress Overview of Bacterial Two-Component Regulatory Systems as Potential Targets for Antimicrobial Chemotherapy, Hirakawa, Hidetada;Kurushima, Jun;Hashimoto, Yusuke;Tomita, Haruyoshi, 2020, ANTIBIOTICS-BASEL, 9, 10

  DOI
• Inactivation of GalU Leads to a Cell Wall-Associated Polysaccharide Defect That Reduces the Susceptibility of Enterococcus faecalis to Bacteriolytic Agents, Kurushima, Jun;Tomita, Haruyoshi, 2021, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 87, 7

  DOI
• Advances of genetic engineering in streptococci and enterococci, Kurushima, Jun;Tomita, Haruyoshi, 2022, MICROBIOLOGY AND IMMUNOLOGY, 66, 9, 411, 417

  DOI
• 肺炎球菌における自然形質転換のダイレクトイメージング(Direct imaging of horizontal gene transfer in Streptococcus pneumoniae), 久留島 潤, Feb. 2021, 76, 1, 16
• VanA型バンコマイシン耐性遺伝子群保有線状プラスミドによるVRE院内感染事例の解析, ;;;;;;, Feb. 2021, 76, 1, 92
• 【エキスパートに聞く 耐性菌と院内感染-産婦人科医に必要な基礎知識】耐性菌各論　診断法と制御・治療戦略　バンコマイシン耐性腸球菌(VRE), ;;, Aug. 2021, 75, 8, 734
• 選抜ワークショップ2:遺伝、分類、疫学　腸球菌の溶菌酵素Bac41は接合フェロモンによって発現制御され、細胞間のプラスミド維持に寄与する(Selected from Oral Session 2: Genetics, taxonomy and Epidemiology　Pheromone-responsive bacteriolysin Bac41 maintains plasmid propagation in Enterococcus faecalis), ;, Feb. 2022, 77, 1, 46
• 腸球菌の線状プラスミドに関する分子疫学解析, ;;;;;;, Feb. 2022, 77, 1, 61
• VanD型バンコマイシン耐性Enterococcus faecalisの分子疫学的解析, ;;;;;;;, Feb. 2022, 77, 1, 112
• Inactivation of GalU Leads to a Cell Wall-Associated Polysaccharide Defect That Reduces the Susceptibility of Enterococcus faecalis to Bacteriolytic Agents., Kurushima Jun;Tomita Haruyoshi, Mar. 2021, Applied and environmental microbiology, 87, 7

  DOI
• Elucidation of host diversity of the VanD-carrying genomic islands in enterococci and anaerobes., Hashimoto Yusuke;Hisatsune Junzo;Suzuki Masato;Kurushima Jun;Nomura Takahiro;Hirakawa Hidetada;Kojima Naoko;Ono Yuichi;Hasegawa Yutaka;Tanimoto Koichi;Sugai Motoyuki;Tomita Haruyoshi, Jan. 2022, JAC-antimicrobial resistance, 4, 1

  DOI
• Advances of genetic engineering in streptococci and enterococci., Kurushima Jun;Tomita Haruyoshi, Jun. 2022, Microbiology and immunology

  DOI
• Vancomycin-resistant Enterococcus(VRE), ;;;;;, Jan. 2016, 60, 1, 68, 82

  DOI
• 選抜ワークショップ2:遺伝、分類、疫学　腸球菌の溶菌酵素Bac41は接合フェロモンによって発現制御され、細胞間のプラスミド維持に寄与する(Selected from Oral Session 2: Genetics, taxonomy and Epidemiology　Pheromone-responsive bacteriolysin Bac41 maintains plasmid propagation in Enterococcus faecalis), ;, Feb. 2022, 77, 1, 46
• 腸球菌の線状プラスミドに関する分子疫学解析, ;;;;;;, Feb. 2022, 77, 1, 61
• VanD型バンコマイシン耐性Enterococcus faecalisの分子疫学的解析, ;;;;;;;, Feb. 2022, 77, 1, 112
• Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq., Kin Ki Jim; Rieza Aprianto; Rutger Koning; Arnau Domenech; Jun Kurushima; Diederik van de Beek; Christina M J E Vandenbroucke-Grauls; Wilbert Bitter; Jan-Willem Veening, 20 Dec. 2022, Cell reports, 41, 12, 111851, 111851, Scientific journal

  DOI
• Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades., Yusuke Hashimoto; Masato Suzuki; Sae Kobayashi; Yuki Hirahara; Jun Kurushima; Hidetada Hirakawa; Takahiro Nomura; Koichi Tanimoto; Haruyoshi Tomita, 18 Apr. 2023, Antimicrobial agents and chemotherapy, 67, 4, e0161922, Scientific journal

  DOI
• Advances of genetic engineering in streptococci and enterococci., Jun Kurushima; Haruyoshi Tomita, Sep. 2022, Microbiology and immunology, 66, 9, 411, 417, Scientific journal

  DOI
• Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades, Hashimoto, Yusuke;Suzuki, Masato;Kobayashi, Sae;Hirahara, Yuki;Kurushima, Jun;Hirakawa, Hidetada;Nomura, Takahiro;Tanimoto, Koichi;Tomita, Haruyoshi, 2023, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 67, 4

  DOI
• 腸球菌の線状プラスミドがE.faeciumに適応し多剤耐性clade内に広がる(Enterococcal linear plasmids adapt to E.faecium and spread within multidrug-resistant clades), ;;;;;;, Feb. 2023, 78, 1, 66
• 腸球菌のプラスミドをエンコードするBac41による溶菌におけるintact cell divisionの役割(Potential role of intact cell division on bacteriolysis by enterococcal plasmid-encoded Bac41), ;, Feb. 2023, 78, 1, 78
• 多様な病原体研究が生み出す新たな生化学領域　薬剤耐性(AMR)遺伝子の拡散に寄与する選択的溶菌酵素, ;, Oct. 2023, 96回, [3S14a
• グラム陽性病原菌の高頻度な遺伝子水平伝播機構の解明, 久留島 潤, Dec. 2023, 78, 4, 179
• Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades., Hashimoto Yusuke;Suzuki Masato;Kobayashi Sae;Hirahara Yuki;Kurushima Jun;Hirakawa Hidetada;Nomura Takahiro;Tanimoto Koichi;Tomita Haruyoshi, Mar. 2023, Antimicrobial agents and chemotherapy, 67, 4

  DOI
• [Mechanism of high-frequent horizontal gene transfer in Gram positive bacterial pathogens]., Kurushima Jun, Nihon saikingaku zasshi. Japanese journal of bacteriology, 78, 4

  DOI
• 多様な病原体研究が生み出す新たな生化学領域　薬剤耐性(AMR)遺伝子の拡散に寄与する選択的溶菌酵素, ;, Oct. 2023, 96回, [3S14a
• グラム陽性病原菌の高頻度な遺伝子水平伝播機構の解明, 久留島 潤, Dec. 2023, 78, 4, 179
• Mechanism of high-frequent horizontal gene transfer in Gram positive bacterial pathogens., Jun Kurushima, 2023, Nihon saikingaku zasshi. Japanese journal of bacteriology, 78, 4, 179, 187, Scientific journal

  DOI
• 臨床医のための微生物学講座(Vol.8)　腸球菌, ;;, Apr. 2024, 289, 2, 156
• 臨床医のための微生物学講座(Vol.8)　腸球菌, ;;, Apr. 2024, 289, 2, 156
• Na+-V-ATPase inhibitor curbs VRE growth and unveils Na+ pathway structure, Kano Suzuki; Yoshiyuki Goto; Akihiro Otomo; Kouki Shimizu; Shohei Abe; Katsuhiko Moriyama; Satoshi Yasuda; Yusuke Hashimoto; Jun Kurushima; Sho Mikuriya; Fabiana L. Imai; Naruhiko Adachi; Masato Kawasaki; Yumi Sato; Satoshi Ogasawara; So Iwata; Toshiya Senda; Mitsunori Ikeguchi; Haruyoshi Tomita; Ryota Iino; Toshio Moriya; Takeshi Murata, 21 Nov. 2024, Nature Structural & Molecular Biology, Scientific journal

  DOI
• 院内アウトブレイクに関与したカルバペネム耐性緑膿菌(CRPA)24株の解析, ;;;;;;;, May 2024, 98回・72回, np200
• 院内アウトブレイクに関与したカルバペネム耐性緑膿菌(CRPA)24株の解析, ;;;;;;;, May 2024, 98回・72回, np200

MISC

• 低濃度VanB型バンコマイシン耐性を持つ腸球菌の臨床単離物の分析(Analysis of the clinical enterococcal isolates with low-level VanB-type vancomycin resistance), 橋本 佑輔; 野村 隆浩; 久留島 潤; 富田 治芳, Feb. 2016, 日本細菌学雑誌, 71, 1, 143, 143
• グローバル化時代の耐性菌感染症 バンコマイシン耐性腸球菌, 富田治芳; 富田治芳; 谷本弘一; 久留島潤; 千葉菜穂子; 野村隆浩; 橋本佑輔, Jan. 2016, 臨床検査, 60, 1, 68, 82

  DOI
• エキスパートに聞く耐性菌と院内感染 産婦人科医に必要な基礎知識 耐性菌各論-診断法と制御・治療戦略 バンコマイシン耐性腸球菌(VRE), 富田治芳; 久留島潤; 橋本佑輔, 2021, 75, 8
• Local spread of VRE ascribed to the interspecies transmission of a vanA-carrying linear plasmid, 橋本佑輔; 鈴木仁人; 野村隆浩; 久留島潤; 平川秀忠; 谷本弘一; 富田治芳; 富田治芳, 2021, 日本細菌学雑誌(Web), 76, 1
• 食肉由来の腸球菌におけるバシトラシン耐性についての研究, 杉岡 佳祐; 野村 隆浩; 橋本 佑輔; 久留島 潤; 谷本 弘一; 富田 治芳, Feb. 2018, 73, 1, 142, 142
• 鶏肉検体からのESBL,AmpC産生腸内細菌科細菌の分離と解析, 大竹 洋輔; 千葉 菜穂子; 久留島 潤; 谷本 弘一; 富田 治芳, Feb. 2018, 73, 1, 149, 149
• 鶏肉検体からのESBL,AmpC産生腸内細菌科細菌の分離と解析, 大竹洋輔; 千葉菜穂子; 久留島潤; 谷本弘一; 富田治芳; 富田治芳, 2018, 73, 1
• 食肉由来の腸球菌におけるバシトラシン耐性についての研究, 杉岡佳祐; 野村隆浩; 橋本佑輔; 久留島潤; 谷本弘一; 富田治芳; 富田治芳, 2018, 73, 1
• VanB型バンコマイシン耐性遺伝子群を保持したバンコマイシン感受性腸球菌に関する研究, 橋本 佑輔; 野村 隆浩; 久留島 潤; 谷本 弘一; 富田 治芳, Feb. 2017, 72, 1, 138, 138
• 鶏肉由来リネゾリド低度耐性腸球菌株の解析, 野村 隆浩; 久留島 潤; 谷本 弘一; 渡邉 治雄; 富田 治芳, Feb. 2017, 72, 1, 140, 140
• 鶏肉からのESBL、AmpC産生腸内細菌科細菌の分離と解析, 大竹 洋輔; 千葉 菜穂子; 久留島 潤; 谷本 弘一; 渡邉 治雄; 富田 治芳, Feb. 2017, 72, 1, 141, 141
• 食肉由来腸球菌のバシトラシン耐性についての研究, 杉岡 佳祐; 野村 隆浩; 久留島 潤; 谷本 弘一; 富田 治芳, Feb. 2017, 72, 1, 142, 142
• 食肉由来腸球菌のバシトラシン耐性についての研究, 杉岡佳祐; 野村隆浩; 久留島潤; 谷本弘一; 富田治芳, 2017, 72, 1
• 鶏肉由来リネゾリド低度耐性腸球菌株の解析, 野村隆浩; 久留島潤; 谷本弘一; 渡邉治雄; 富田治芳; 富田治芳, 2017, 72, 1
• VanB型バンコマイシン耐性遺伝子群を保持したバンコマイシン感受性腸球菌に関する研究, 橋本佑輔; 野村隆浩; 久留島潤; 谷本弘一; 富田治芳; 富田治芳, 2017, 72, 1
• 鶏肉からのESBL,AmpC産生腸内細菌科細菌の分離と解析, 大竹洋輔; 千葉菜穂子; 久留島潤; 谷本弘一; 渡邉治雄; 富田治芳; 富田治芳, 2017, 72, 1
• 実験動物マウスの細菌感染症フロントライン 腸管病原性大腸菌モデルとしてのCitrobacter rodentium感染症(Front-line of Bacterial Infectious Diseases of Mice Citrobacter rodentium infection as model of human A/E pathogens), 久留島 潤, Feb. 2016, 日本細菌学雑誌, 71, 1, 39, 39
• ボルデテラ属細菌のエフェクターBopNのimportin beta-1を介した核移行メカニズムの解析, 千葉紗由利; 桑江朝臣; 久留島潤; 阿部章夫, 2012, 35th
• 臨床医のための微生物学講座(Vol.8) 腸球菌, 富田 治芳; 久留島 潤; 橋本 佑輔, Apr. 2024, 289, 2, 156, 163
• グラム陽性病原菌の高頻度な遺伝子水平伝播機構の解明, 久留島 潤, Dec. 2023, 78, 4, 179, 187
• Enterococcal Highly Conjugative Plasmids, 富田治芳; 富田治芳; 谷本弘一; 平川秀忠; 久留島潤; 橋本祐輔; 野村隆浩, 2020, Journal of Environmental Biotechnology (Web), 20, 1

Presentations

• 腸管病原性大腸菌モデルとしてのCitrobacter rodentium感染症, 久留島潤, 第89回日本細菌学会総会, Mar. 2016
• 腸球菌Enterococcus faecalis が産生するバクテリオシンBac41 の機能解析, 久留島潤、富田治芳, 第22回 Lancefieldレンサ球菌研究会, Jun. 2013
• ボルデテラ属細菌が産生する分泌性制御因子BspRの同定と機能解析, 久留島潤、桑江朝臣、阿部章夫, 第６回細菌学若手コロッセウム, Aug. 2012
• 腸球菌Enterococcus faecalisが産生する二成分性バクテリオシンBac41の溶菌作用機序の解析, 久留島潤、富田治芳, 第86回日本細菌学会総会, Mar. 2013
• A novel type III secreted protein BspR regulates the virulence factors in Bordetella bronchiseptica, Jun Kurushima, Asaomi Kuwae, Akio Abe, 第85回日本細菌学会総会, Mar. 2012
• 腸球菌バクテリオシンBac41の機能解析, 久留島潤、林幾江、菅井基行、富田治芳, 第7回細菌学若手コロッセウム, Aug. 2013
• Functional analysis of bacteriocin Bac41 produced by Enterococcus faecalis clinical isolates, Jun Kurushima, Haruyoshi Tomita, The 12th Awaji International Forum on Infection and Immunity, 12 Sep. 2013, Hyogo
• 腸球菌バクテリオシンBac41による殺菌メカニズムの解析, 久留島潤, 富田治芳, 第96回日本細菌学会関東支部総会, Nov. 2013
• Functional analysis of bacteriocin Bac41 produced by Enterococcus faecalis, Jun Kurushima, Sociomicrobiology Meeting at Gunma University, Jan. 2014, Maebashi, Gunma
• Functional analysis of bacteriocin Bac41 produced by Enterococcus faecalis, Jun Kurushima, Ikue Hayashi, Daisuke Nakane, Takayuki Nishizaka, Motoyuki Sugai, Haruyoshi Tomita, 4th ASM Conference on Enterococci, Cartagena, Mar. 2014, Colombia
• 腸球菌Enterococcus faecalisが産生するバクテリオシンタンパク質BacL1の細胞壁ターゲッティング, 久留島潤, 富田治芳, 第46回レンサ球菌研究会, Jun. 2014
• 腸球菌バクテリオシンBacL1の細胞壁ターゲッティング, 久留島潤, 中根大介, 西坂崇之, 富田治芳, 第8回細菌学若手コロッセウム, Aug. 2014
• 臨床分離Enterococcus faecalisが産生する溶菌タンパク質BacL1の特異的ターゲッティング, 久留島潤, 中根大介, 野村隆浩, 西坂崇之, 富田治芳, 第88回日本細菌学会, Mar. 2015
• 臨床分離Enterococcus faecalisにおける選択的溶菌酵素Bac41の拡散と多様性, 久留島潤, 富田治芳, 第47回レンサ球菌研究会, Jul. 2015
• 腸球菌プラスミドにコードされる溶菌酵素 Bac41 の 作用機構と遺伝子水平伝搬における役割, 久留島潤, 富田治芳, 第23回分子寄生虫学ワークショップ・第13回分子寄生虫・マラリア研究フォーラム合同大会, Aug. 2015
• Molecular mechanism of bacteriolysis and self-resistance by enterococcal two-component bacteriolysin Bac41, Jun Kurushima, Haruyoshi Tomita, The 14th Awaji International Forum on Infection and Immunity, Sep. 2015, Hyogo
• 腸球菌バクテリオシンBac41の溶菌作用機構, 久留島潤, 富田治芳, 第98回日本細菌学会関東支部総会, Oct. 2015
• 日和見病原菌Enterococcus faecalisのプラスミドにコードされる溶菌酵素Bac41の作用機構, 久留島潤, 富田治芳, 第38回日本分子生物学会・第88回日本生化学会合同大会, Dec. 2015
• Identification and characterization of a novel type III effector in Bordetella, Jun Kurushima, Akio Abe, International Union on Microbiological Society 2011 Congress, Sep. 2011, Hokkaido
• ボルデテラ属細菌の新規 III 型エフェクターの同定と機能解析, 久留島潤, 桑江朝臣, 阿部章夫, 第5回細菌学若手コロッセウム, Aug. 2011
• 腸球菌バクテリオシンBac41による殺菌メカニズムの解析, 久留島潤, 林幾江, 中根大介, 西坂崇之, 菅井基行, 富田治芳, 第87回日本細菌学会総会, Mar. 2014

Awards

• Oct. 2010
• Oct. 2008
• Best Poster Award, Dec. 2021
• 2015
• Mar. 2023
• Feb. 2024

Educational Activities

Teaching Experience

• 2021, 2024

Awards

• Best teacher award, 2023

Social Contribution

Academic Contribution

• The 3rd Asian Pneumococcal Symposium program committee, Competition etc
• 2021年日本細菌学会関東支部インターラボセミナー 世話人, Competition etc
• 第9回細菌学若手コロッセウム, Competition etc
• 第10回細菌学若手コロッセウム, Competition etc