Researcher Profile and Settings

Researcher

• Name

  Ichinose Sotaro

Affiliation

• Anatomy, Assistant Professor

Profile and Settings

• Name

  Ichinose, Sotaro

Affiliation

• Gunma University, Graduate School of Medicine, Assistant professor

Affiliation

• Affiliation

  Graduate School of Medicine

Education

• Mar. 2013, The University of Tokyo, Graduate School of Medicine
• Mar. 2007, The University of Tokyo, Faculty of Medicine, School of Health Sciences and Nursing
• Mar. 2009, The University of Tokyo, Graduate School of Medicine, Medical Science Graduate Program

Degree

• Doctor of philosophy

Association Memberships

• The Japanese Association of Anatomists, Jan. 2020, 9999
• The Japan Neuroscience Society, Jan. 2016, 9999
• American Society for Cell Biology, Jan. 2015, 9999
• May 2023, 9999
• The Molecular Biology Society of Japan, Jan. 2022, 9999

Research Experience

• Apr. 2019, 9999, Gunma University, Department of Anatomy, Graduate School of Medicine, Assistant Professor, Assistant prof lv
• Apr. 2013, Mar. 2019, The University of Tokyo, Department of Anatomy and Cell Biology, Graduate School of Medicine, Postdoctoral fellow, Researcher postdoc lv

Research Activities

Research Areas

• Life sciences, Cell biology
• Life sciences, Anatomy
• Life sciences, Molecular biology

Research Interests

• Synaptogenesis
• Neuronal cytoskeleton
• Intracellular transport
• Kinesin
• Synapse

Published Papers

• Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport., Shogo Yoshihara, Xuguang Jiang, Momo Morikawa, Tadayuki Ogawa, Sotaro Ichinose, Hirooki Yabe, Akiyoshi Kakita, Manabu Toyoshima, Yasuto Kunii, Takeo Yoshikawa, Yosuke Tanaka, Nobutaka Hirokawa, 13 Apr. 2021, Cell reports, 35, 2, 108971, 108971

  DOI
• Mechanism of Activity-Dependent Cargo Loading via the Phosphorylation of KIF3A by PKA and CaMKIIa., Sotaro Ichinose; Tadayuki Ogawa; Nobutaka Hirokawa, 02 Sep. 2015, Neuron, 87, 5, 1022, 35, Scientific journal

  DOI
• KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth., Fang Xu; Hironori Takahashi; Yosuke Tanaka; Sotaro Ichinose; Shinsuke Niwa; Matthew P Wicklund; Nobutaka Hirokawa, 01 Oct. 2018, The Journal of cell biology, 217, 10, 3480, 3496, Scientific journal

  DOI
• The Spatiotemporal Construction of the Axon Initial Segment via KIF3/KAP3/TRIM46 Transport under MARK2 Signaling., Sotaro Ichinose; Tadayuki Ogawa; Xuguang Jiang; Nobutaka Hirokawa, 27 Aug. 2019, Cell reports, 28, 9, 2413, 2426, Scientific journal

  DOI
• Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport., Shogo Yoshihara; Xuguang Jiang; Momo Morikawa; Tadayuki Ogawa; Sotaro Ichinose; Hirooki Yabe; Akiyoshi Kakita; Manabu Toyoshima; Yasuto Kunii; Takeo Yoshikawa; Yosuke Tanaka; Nobutaka Hirokawa, 13 Apr. 2021, Cell reports, 35, 2, 108971, 108971, Scientific journal

  DOI
• Correlative microscopy and block-face imaging (CoMBI): a 3D imaging method with wide applicability in the field of biological science, Yuki Tajika; Nobukazu Ishii; Yoshihiro Morimura; Kyosuke Fukuda; Mitsuaki Shikada; Tohru Murakami; Sotaro Ichinose; Yuhei Yoshimoto; Hirohide Iwasaki, 28 Feb. 2023, Anatomical Science International, 98, 353, 359, Scientific journal

  DOI
• Recent technological advances in correlative light and electron microscopy for the comprehensive analysis of neural circuits, Hirohide Iwasaki; Sotaro Ichinose; Yuki Tajika; Tohru Murakami, 30 Nov. 2022, Frontiers in Neuroanatomy, 16, 1061078, Scientific journal

  DOI
• Teneurin-2 at the Synapse Construction Site is a Signpost for Cargo Unloading from Motor Proteins, Sotaro Ichinose; Yoshihiro Susuki; Ryosuke Kaneko; Hirohide Iwasaki, 14 Sep. 2022, bioRxiv

  DOI
• The two‐step cargo recognition mechanism of heterotrimeric kinesin, Xuguang Jiang; Tadayuki Ogawa; Kento Yonezawa; Nobutaka Shimizu; Sotaro Ichinose; Takayuki Uchihashi; Wataru Nagaike; Toshio Moriya; Naruhiko Adachi; Masato Kawasaki; Naoshi Dohmae; Toshiya Senda; Nobutaka Hirokawa, 14 Aug. 2023, EMBO reports, e56864, Scientific journal

  DOI
• Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis, Sotaro Ichinose; Yoshihiro Susuki; Nobutake Hosoi; Ryosuke Kaneko; Mizuho Ebihara; Hirokazu Hirai; Hirohide Iwasaki, 05 Jun. 2023, eLife, 12, e83276, Scientific journal

  DOI
• Recent technological advances in correlative light and electron microscopy for the comprehensive analysis of neural circuits, Iwasaki, Hirohide;Ichinose, Sotaro;Tajika, Yuki;Murakami, Tohru, 2022, FRONTIERS IN NEUROANATOMY, 16

  DOI
• Correlative microscopy and block-face imaging (CoMBI): a 3D imaging method with wide applicability in the field of biological science, Tajika, Yuki;Ishii, Nobukazu;Morimura, Yoshihiro;Fukuda, Kyosuke;Shikada, Mitsuaki;Murakami, Tohru;Ichinose, Sotaro;Yoshimoto, Yuhei;Iwasaki, Hirohide, 2023, ANATOMICAL SCIENCE INTERNATIONAL, 98, 3, 353, 359

  DOI
• Interaction between Teneurin-2 and microtubules via EB proteins provides a platform for GABAA receptor exocytosis, Ichinose, Sotaro;Susuki, Yoshihiro;Hosoi, Nobutake;Kaneko, Ryosuke;Ebihara, Mizuho;Hirai, Hirokazu;Iwasaki, Hirohide;Ori-McKenney, Kassandra M., 2023, ELIFE, 12

  DOI
• The two-step cargo recognition mechanism of heterotrimeric kinesin, Jiang, Xuguang;Ogawa, Tadayuki;Yonezawa, Kento;Shimizu, Nobutaka;Ichinose, Sotaro;Uchihashi, Takayuki;Nagaike, Wataru;Moriya, Toshio;Adachi, Naruhiko;Kawasaki, Masato;Dohmae, Naoshi;Senda, Toshiya;Hirokawa, Nobutaka, 2023, EMBO REPORTS

  DOI
• Recent technological advances in correlative light and electron microscopy for the comprehensive analysis of neural circuits., Iwasaki Hirohide;Ichinose Sotaro;Tajika Yuki;Murakami Tohru, Nov. 2022, Frontiers in neuroanatomy, 16

  DOI
• Correlative microscopy and block-face imaging (CoMBI): a 3D imaging method with wide applicability in the field of biological science., Tajika Yuki;Ishii Nobukazu;Morimura Yoshihiro;Fukuda Kyosuke;Shikada Mitsuaki;Murakami Tohru;Ichinose Sotaro;Yoshimoto Yuhei;Iwasaki Hirohide, Feb. 2023, Anatomical science international, 98, 3

  DOI
• The two-step cargo recognition mechanism of heterotrimeric kinesin., Jiang Xuguang;Ogawa Tadayuki;Yonezawa Kento;Shimizu Nobutaka;Ichinose Sotaro;Uchihashi Takayuki;Nagaike Wataru;Moriya Toshio;Adachi Naruhiko;Kawasaki Masato;Dohmae Naoshi;Senda Toshiya;Hirokawa Nobutaka, Aug. 2023, EMBO reports, 24, 11

  DOI

MISC

• The roles of teneruin-2 in neuron, Sotaro Ichinose, Hirohide Iwasaki, Jul. 2020
• Mechanism of Activity-Dependent Cargo Loading via the Phosphorylation of KIF3A by PKA and CaMKIIa., Aug. 2015, https://first.lifesciencedb.jp/archives/11676

  DOI
• Faculty Opinions Article Recommendation, Jul. 2015, https://facultyopinions.com/article/725764358
• 抗体標識キットアプリケーションノート, Jan. 2024
• 東大、キネシンによる軸索基部形成の時間的空間的制御機構を解明, 28 Aug. 2019

Presentations

• The roles of teneurin-2 in neuron, Sotaro Ichinose; Hirohide Iwasaki, 第43回日本神経科学大会, Jul. 2020, Jul. 2020, Jul. 2020
• The Spatiotemporal Construction of Axon Initial Segment via KIF3/KAP3/TRIM46 Transport under MARK2 Signaling., Ichinose S; Ogawa T; Jiang X; Hirokawa N, American Society for Cell Biology Annual Meeting, Dec. 2019, Dec. 2019, Dec. 2019
• KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth., Xu F; Takahashi H; Tanaka Y; Ichinose S; Niwa S; Wicklund MP; Hirokawa N, American Society for Cell Biology Annual Meeting, Dec. 2018, Dec. 2018, Dec. 2018
• Mechanism of Activity-Dependent Cargo Loading via the Phosphorylation of KIF3A by PKA and CaMKIIa., Ichinose S; Ogawa T; Hirokawa N, International Congress of Cell Biology, 23 Jul. 2016
• Mechanism of Activity-Dependent Cargo Loading via the Phosphorylation of KIF3A by PKA and CaMKIIa., Ichinose S; Ogawa T; Hirokawa N, American Society for Cell Biology Annual Meeting, Dec. 2015, Dec. 2015, Dec. 2015
• 抑制性シナプス形成における微小管の役割, 一ノ瀬 聡太郎; 岩﨑 広英, 第44回日本神経科学大会, 31 Jul. 2021
• ベタインはKIF3によるCRMP2輸送を機能的に補い統合失調症様の症状を改善する, 吉原 壮悟; 蒋 緒光; 森川 桃; 小川 覚之; 一ノ瀬 聡太郎; 矢部 博興; 柿田 明美; 豊島 学; 國井 泰人; 吉川 武男; 田中 庸介; 廣川 信隆, 第44回日本神経科学大会, 31 Jul. 2021
• Mechanism of Activity-Dependent Cargo Loading via the Phosphorylation of KIF3A by PKA and CaMKIIa., Ichinose S; Ogawa T; Hirokawa N, 第39回日本神経科学大会, Jul. 2016
• 抑制性シナプスの多様性解析, 一ノ瀬聡太郎; 岩﨑広英, 第128回日本解剖学会総会・全国学術集会, 18 Mar. 2023
• Teneurin-2 at synapse construction site is a signpost for protein accumulation, Sotaro Ichinose; Hirohide Iwasaki, MBSJ2022, 01 Dec. 2022
• 抑制性シナプスの多様性解析, 海老原 瑞穂; 一ノ瀬 聡太郎; 鈴木 美博; 岩﨑 広英, 第110回 日本解剖学会 関東支部学術集会, 01 Oct. 2022
• Teneurin-2 at synapse construction site is a signpost for protein accumulation, Sotaro Ichinose; Hirohide Iwasaki, 第45回日本神経科学大会, 01 Jul. 2022
• 抑制性シナプス形成における微小管の役割, 一ノ瀬 聡太郎; 岩﨑 広英, 第127回日本解剖学会総会・全国学術集会, 27 Mar. 2022
• 接着分子と細胞骨格分子による抑制性シナプス形成機序の解析, 一ノ瀬聡太郎; 岩﨑広英, 第129回日本解剖学会総会・全国学術集会, 22 Mar. 2024
• 接着分子テニューリン2の海馬における分子局在, 海老原瑞穂; 一ノ瀬聡太郎; 鈴木美博; 岩﨑広英, 第129回日本解剖学会総会・全国学術集会, 21 Mar. 2024
• The two-step cargo recognition and binding mechanism of heterotrimeric kinesin, X. Jiang1, T. Ogawa2, K. Yonezawa3, N. Shimizu4, S. Ichinose5, T. Uchihashi6, W. Nagaike6, T. Moriya4, N. Adachi4, M. Kawasaki4, N. Dohmae7, T. Senda4, N. Hirokawa8, American Society for Cell Biology Annual Meeting, 05 Dec. 2023
• Interaction Between Teneurin-2 and Microtubules via EB Proteins Provides a Platform for GABAAReceptor Exocytosis, Sotaro Ichinose; Hirohide Iwasaki, American Society for Cell Biology Annual Meeting, 03 Dec. 2023
• The interaction of Teneurin-2 with microtubules through end-binding proteins facilitates the accumulation of proteins at inhibitory postsynapses, Sotaro Ichinose; Yoshihiro Susuki; Ryosuke Kaneko; Hirohide Iwasaki, 第46回日本神経科学大会, 01 Aug. 2023
• The interaction of Teneurin-2 with microtubules through end-binding proteins facilitates the accumulation of proteins at inhibitory postsynapses, Sotaro Ichinose; Yoshihiro Susuki; Ryosuke Kaneko; Hirohide Iwasaki, The 49th Naito Conference, 05 Jul. 2023, 04 Jul. 2023, 07 Jul. 2023
• EBとTEN2の相分離が抑制性シナプスの形成を促進する, 一ノ瀬 聡太郎; 岩﨑 広英, NEURO2024 (第47回日本神経科学大会他合同大会), 25 Jul. 2024
• 接着分子テニューリン2の海馬における分子局在, 海老原 瑞穂; 一ノ瀬 聡太郎; 岩﨑 広英, NEURO2024 (第47回日本神経科学大会他合同大会), 24 Jul. 2024
• The phase separation of EB and TEN2 promotes inhibitory synapse formation, Sotaro Ichinose; Hirohide Iwasaki, 21st IUPAB Congress 2024, 27 Jun. 2024

Awards

• Jul. 2016
• Oct. 2023

Research Projects

• Mechanisms of Differential Cytoskeletal Assembly at Excitatory and Inhibitory Synapses, Apr. 2020, Mar. 2024, 20K16104

  対象リソースIRI
• 01 Apr. 2024, 31 Mar. 2027, 24K09994

  対象リソースIRI
• Apr. 2024, Mar. 2025

Educational Activities

Teaching Experience

• Medical Research Training
• Anatomy