Researcher Profile and Settings

Researcher

• Name

  Uchiyama Akihiko

Affiliation

• Dematology, Lecturer

Profile and Settings

• Name

  Akihiko, Uchiyama

Association Memberships

• Society for investigative dermatology
• THE JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY
• THE JAPANESE DERMATOLOGICAL ASSOCIATION

Research Experience

• Jun. 2020, 9999
• Apr. 2019, 9999, Gunma university hospital, Department of dermatology, clinical staff
• Sep. 2016, Mar. 2019, National Institutes of Health
• Apr. 2015, Sep. 2016
• Apr. 2012, Mar. 2015, Gunma University, Graduate School of Medicine
• Apr. 2010, Mar. 2012
• Apr. 2008, Mar. 2010

Research Activities

Research Areas

• Life sciences, Dermatology

Research Interests

• angiogenesis
• SOX2
• Mesenchymal stem cell
• pressure ulcer
• wound healing

Published Papers

• Demographic and clinical characteristics of cytomegalovirus reactivation in dermatomyositis., Akiko Sekiguchi; Yuta Inoue; Sahori Yamazaki; Akihiko Uchiyama; Yukie Endo; Osamu Ishikawa; Sei-Ichiro Motegi, 26 May 2020, The Journal of dermatology, Scientific journal

  DOI
• Prevalence and clinical characteristics of earlobe crease in systemic sclerosis: Possible association with vascular dysfunction., Akiko Sekiguchi; Yuta Inoue; Sahori Yamazaki; Akihiko Uchiyama; Osamu Ishikawa; Shiko Kuribayashi; Toshio Uraoka; Kenichiro Hara; Kouichi Yamaguchi; Toshitaka Maeno; Mitsuo Uchida; Hiroshi Koyama; Sei-Ichiro Motegi, 18 May 2020, The Journal of dermatology, Scientific journal

  DOI
• Protective effect of dimethyl fumarate for the development of pressure ulcers after cutaneous ischemia-reperfusion injury., Yuta Inoue; Akihiko Uchiyama; Akiko Sekiguchi; Sahori Yamazaki; Chisako Fujiwara; Yoko Yokoyama; Sachiko Ogino; Ryoko Torii; Mari Hosoi; Ryoko Akai; Takao Iwawaki; Osamu Ishikawa; Sei-Ichiro Motegi, 30 Apr. 2020, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

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• Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model., Sahori Yamazaki; Akiko Sekiguchi; Akihiko Uchiyama; Chisako Fujiwara; Yuta Inoue; Yoko Yokoyama; Sachiko Ogino; Ryoko Torii; Mari Hosoi; Ryoko Akai; Takao Iwawaki; Osamu Ishikawa; Sei-Ichiro Motegi, 28 Jan. 2020, Scientific reports, 10, 1, 1349, 1349

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• Inhibitory effect of kaempferol on skin fibrosis in systemic sclerosis by the suppression of oxidative stress., Akiko Sekiguchi; Sei-Ichiro Motegi; Chisako Fujiwara; Sahori Yamazaki; Yuta Inoue; Akihiko Uchiyama; Ryoko Akai; Takao Iwawaki; Osamu Ishikawa, Oct. 2019, Journal of dermatological science, 96, 1, 8, 17

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• SOX2 Epidermal Overexpression Promotes Cutaneous Wound Healing via Activation of EGFR/MEK/ERK Signaling Mediated by EGFR Ligands., Uchiyama A; Nayak S; Graf R; Cross M; Hasneen K; Gutkind JS; Brooks SR; Morasso MI, Aug. 2019, The Journal of investigative dermatology, 139, 8, 1809, 1820.e8

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• The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y₂ Purinergic Receptor., Perera LMB; Sekiguchi A; Uchiyama A; Uehara A; Fujiwara C; Yamazaki S; Yokoyama Y; Ogino S; Torii R; Hosoi M; Ishikawa O; Motegi SI, Apr. 2019, The Journal of investigative dermatology, 139, 4, 890, 899

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• Suppressive Regulation by MFG-E8 of Latent Transforming Growth Factor β-Induced Fibrosis via Binding to αv Integrin: Significance in the Pathogenesis of Fibrosis in Systemic Sclerosis., Fujiwara C; Uehara A; Sekiguchi A; Uchiyama A; Yamazaki S; Ogino S; Yokoyama Y; Torii R; Hosoi M; Suto C; Tsunekawa K; Murakami M; Ishikawa O; Motegi SI, Feb. 2019, Arthritis & rheumatology (Hoboken, N.J.), 71, 2, 302, 314

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• Inhibitory Regulation of Skin Fibrosis in Systemic Sclerosis by Apelin/APJ Signaling., Yokoyama Y; Sekiguchi A; Fujiwara C; Uchiyama A; Uehara A; Ogino S; Torii R; Ishikawa O; Motegi SI, Oct. 2018, Arthritis & rheumatology (Hoboken, N.J.), 70, 10, 1661, 1672

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• Transcriptional signature primes human oral mucosa for rapid wound healing., Iglesias-Bartolome R; Uchiyama A; Molinolo AA; Abusleme L; Brooks SR; Callejas-Valera JL; Edwards D; Doci C; Asselin-Labat ML; Onaitis MW; Moutsopoulos NM; Gutkind JS; Morasso MI, Jul. 2018, Science translational medicine, 10, 451

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• A data mining paradigm for identifying key factors in biological processes using gene expression data., Li J; Zheng L; Uchiyama A; Bin L; Mauro TM; Elias PM; Pawelczyk T; Sakowicz-Burkiewicz M; Trzeciak M; Leung DYM; Morasso MI, Yu P, Jun. 2018, Scientific reports, 8, 1, 9083

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• Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress., Akiko Sekiguchi; Sei-Ichiro Motegi; Akihiko Uchiyama; Akihito Uehara; Chisako Fujiwara; Sahori Yamazaki; Buddhini Perera; Hideharu Nakamura; Sachiko Ogino; Yoko Yokoyama; Ryoko Akai; Takao Iwawaki; Osamu Ishikawa, May 2018, Journal of dermatological science, 90, 2, 144, 153

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• Trigeminal trophic syndrome: Analysis of the number of peripheral nerve fibres and blood vessels in the lesional skin, Akihiko Uchiyama; Sei-Ichiro Motegi; Chisako Fujiwara; Akiko Sekiguchi; Masahito Yasuda; Hiroo Amano; Osamu Ishikawa, 01 Feb. 2018, Australasian Journal of Dermatology, 59, 1, 59, 61

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• Prediction of Negative Outcomes in Non-Surgical Treatment for Appendiceal Abscess in Adults., Sadakari Y; Date S; Murakami S; Ichimiya S; Nishimura S; Kawaji H; Sagara A; Castillo JR; Ishikawa M; Kamimura T; Uchiyama A; Nakamura M, 2018, Journal of the anus, rectum and colon, 2, 2, 59, 65

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• Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress., Sei-Ichiro Motegi; Akiko Sekiguchi; Akihiko Uchiyama; Akihito Uehara; Chisako Fujiwara; Sahori Yamazaki; Buddhini Perera; Hideharu Nakamura; Sachiko Ogino; Yoko Yokoyama; Ryoko Akai; Takao Iwawaki; Osamu Ishikawa, 07 Dec. 2017, Scientific reports, 7, 1, 17186, 17186

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• Mesenchymal stem cells-derived MFG-E8 accelerates diabetic cutaneous wound healing, Akihiko Uchiyama; Sei-ichiro Motegi; Akiko Sekiguchi; Chisako Fujiwara; Buddhini Perera; Sachiko Ogino; Yoko Yokoyama; Osamu Ishikawa, Jun. 2017, JOURNAL OF DERMATOLOGICAL SCIENCE, 86, 3, 187, 197, Scientific journal

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• Internal hernia after laparoscopic gastrectomy with Roux-en-Y reconstruction for gastric cancer., Kimura H; Ishikawa M; Nabae T; Matsunaga T; Murakami S; Kawamoto M; Kamimura T; Uchiyama A, May 2017, Asian journal of surgery, 40, 3, 203, 209

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• Topical betamethasone butyrate propionate exacerbates pressure ulcers after cutaneous ischemia-reperfusion injury, Akihiko Uchiyama; Kazuya Yamada; Buddhini Perera; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Osamu Ishikawa; Sei-ichiro Motegi, Sep. 2016, EXPERIMENTAL DERMATOLOGY, 25, 9, 678, 683, Scientific journal

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• Mechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis, Akihito Uehara; Sei-ichiro Motegi; Kazuya Yamada; Akihiko Uchiyama; Buddhini Perera; Sayaka Toki; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Osamu Ishikawa, Sep. 2016, SCIENTIFIC REPORTS, 6, 34012, Scientific journal

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• Angioinvasive lymphomatoid papulosis (type E): a first Japanese case, Akihiko Uchiyama; Sei-ichiro Motegi; Osamu Ishikawa, Sep. 2016, EUROPEAN JOURNAL OF DERMATOLOGY, 26, 5, 507, 508

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• Reply: "Erosive oral lichen planus as a sign of paraneoplastic pemphigus", Sei-ichiro Motegi; Akihiko Uchiyama; Sayaka Toki; Kazuya Yamada; Hiroo Amano; Osamu Ishikawa, Aug. 2016, JOURNAL OF DERMATOLOGY, 43, 8, 984, 984

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• Increased susceptibility to oxidative stress- and ultraviolet A-induced apoptosis in fibroblasts in atypical progeroid syndrome/atypical Werner syndrome with LMNA mutation, Sei-ichiro Motegi; Akihiko Uchiyama; Kazuya Yamada; Sachiko Ogino; Yoko Yokoyama; Buddhini Perera; Yuko Takeuchi; Osamu Ishikawa, Aug. 2016, EXPERIMENTAL DERMATOLOGY, 25, 20, 27, Scientific journal

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• MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell-Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages, Kazuya Yamada; Akihiko Uchiyama; Akihito Uehara; Buddhini Perera; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Mark C. Udey; Osamu Ishikawa; Sei-ichiro Motegi, Jul. 2016, CANCER RESEARCH, 76, 14, 4283, 4292, Scientific journal

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• Successful Treatment of Multicentric Reticulohistiocytosis with Adalimumab, Prednisolone and Methotrexate, Sei-ichiro Motegi; Yukio Yonemoto; Shinya Yanagisawa; Sayaka Toki; Akihiko Uchiyama; Kazuya Yamada; Osamu Ishikawa, 2016, ACTA DERMATO-VENEREOLOGICA, 96, 1, 124, 125, Scientific journal

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• Beneficial effect of botulinum toxin A on Raynaud's phenomenon in Japanese patients with systemic sclerosis: A prospective, case series study, Sei-ichiro Motegi; Kazuya Yamada; Sayaka Toki; Akihiko Uchiyama; Yuka Kubota; Tetsuya Nakamura; Osamu Ishikawa, Jan. 2016, JOURNAL OF DERMATOLOGY, 43, 1, 56, 62, Scientific journal

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• Lymphomatoid papulosis associated with follicular B-cell lymphoma in lymph nodes, Akihiko Uchiyama; Sei-ichiro Motegi; Osamu Ishikawa, Nov. 2015, JOURNAL OF DERMATOLOGY, 42, 11, 1129, 1130

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• Lichen planus complicated with thymoma: Report of three Japanese cases and review of the published work, Sei-ichiro Motegi; Akihiko Uchiyama; Kazuya Yamada; Sayaka Toki; Hiroo Amano; Osamu Ishikawa, Nov. 2015, JOURNAL OF DERMATOLOGY, 42, 11, 1072, 1077, Scientific journal

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• Epstein-Barr virus-positive diffuse large B-cell lymphoma following acute myeloid leukemia: a common clonal origin indicated by chromosomal translocation t(3;4)(p25;q21)., Higuchi M; Sasaki S; Kawadoko S; Uchiyama H; Yasui T; Kamihira T; Aoki K; Sasaguri T; Nakano R; Uchiyama A; Muta T; Ohshima K, Oct. 2015, International journal of hematology, 102, 4, 482, 487

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• Successful treatment of neutrophilic dermatosis in patient with Crohn's disease with granulocyte and monocyte adsorption apheresis, Sei-ichiro Motegi; Akihiko Uchiyama; Sayaka Toki; Kazuya Yamada; Hiroo Amano; Osamu Ishikawa, Aug. 2015, JOURNAL OF DERMATOLOGY, 42, 8, 836, 837

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• Poorly Differentiated Squamous Cell Carcinoma in an Atomic Bomb Survivor, Akihiko Uchiyama; Sei-ichiro Motegi; Osamu Ishikawa, Jun. 2015, ANNALS OF DERMATOLOGY, 27, 3, 332, 334

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• Protective Effect of MFG-E8 after Cutaneous Ischemia-Reperfusion Injury, Akihiko Uchiyama; Kazuya Yamada; Buddhini Perera; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Osamu Ishikawa; Sei-ichiro Motegi, Apr. 2015, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 135, 4, 1157, 1165, Scientific journal

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• Clinical and laboratory features of systemic sclerosis complicated with localized scleroderma, Sayaka Toki; Sei-ichiro Motegi; Kazuya Yamada; Akihiko Uchiyama; Sahori Kanai; Masayoshi Yamanaka; Osamu Ishikawa, Mar. 2015, JOURNAL OF DERMATOLOGY, 42, 3, 283, 287, Scientific journal

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• Protective effect of botulinum toxin A after cutaneous ischemia-reperfusion injury, Akihiko Uchiyama; Kazuya Yamada; Buddhini Perera; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Osamu Ishikawa; Sei-ichiro Motegi, Mar. 2015, SCIENTIFIC REPORTS, 5, 9072, Scientific journal

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• Demographic and clinical features of systemic sclerosis patients with anti-RNA polymerase III antibodies, Sei-ichiro Motegi; Sayaka Toki; Kazuya Yamada; Akihiko Uchiyama; Osamu Ishikawa, Feb. 2015, JOURNAL OF DERMATOLOGY, 42, 2, 189, 192, Scientific journal

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• Pathogenesis of Multiple Lentigines in LEOPARD Syndrome with PTPN11 Gene Mutation, Sei-ichiro Motegi; Yoko Yokoyama; Sachiko Ogino; Kazuya Yamada; Akihiko Uchiyama; Buddhini Perera; Yuko Takeuchi; Hiroshi Ohnishi; Osamu Ishikawa, 2015, ACTA DERMATO-VENEREOLOGICA, 95, 8, 978, 984, Scientific journal

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• Cutaneous Marginal Zone B-cell Lymphoma Evolving into Anetoderma: A Role of Matrix Metalloproteinases?, Akihiko Uchiyama; Sei-ichiro Motegi; Etsuko Okada; Nobuyuki Hirai; Yayoi Nagai; Atsushi Tamura; Osamu Ishikawa, 2015, ACTA DERMATO-VENEREOLOGICA, 95, 4, 499, 500

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• First Japanese case of atypical progeroid syndrome/atypical Werner syndrome with heterozygous LMNA mutation, Sei-ichiro Motegi; Yoko Yokoyama; Akihiko Uchiyama; Sachiko Ogino; Yuko Takeuchi; Kazuya Yamada; Tomoyasu Hattori; Hiroaki Hashizume; Yuichi Ishikawa; Makoto Goto; Osamu Ishikawa, Dec. 2014, JOURNAL OF DERMATOLOGY, 41, 12, 1047, 1052, Scientific journal

  DOI
• Demographic and clinical features of autoimmune thyroid disorder in Japanese patients with systemic sclerosis, Sayaka Toki; Sei-ichiro Motegi; Kazuya Yamada; Akihiko Uchiyama; Osamu Ishikawa, Dec. 2014, JOURNAL OF DERMATOLOGY, 41, 12, 1053, 1057, Scientific journal

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• Skin Sclerosis with Elevation of Serum Interleukin-6 That Is Possibly Associated with Immunoglobulin 4-Related Disease, Sei-ichiro Motegi; Akihiko Uchiyama; Kazuya Yamada; Akihito Uehara; Sayaka Toki; Osamu Ishikawa, Dec. 2014, ANNALS OF DERMATOLOGY, 26, 6, 766, 767

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• Elevated plasma homocysteine level is possibly associated with skin sclerosis in a series of Japanese patients with systemic sclerosis, Sei-ichiro Motegi; Sayaka Toki; Kazuya Yamada; Akihiko Uchiyama; Osamu Ishikawa, Nov. 2014, JOURNAL OF DERMATOLOGY, 41, 11, 986, 991, Scientific journal

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• Primary Granulocytic Sarcoma of the Skin without Hematologic Disorders, Akihiko Uchiyama; Sei-ichiro Motegi; Kazuya Yamada; Hiroo Amano; Osamu Ishikawa, Oct. 2014, ANNALS OF DERMATOLOGY, 26, 5, 653, 655

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• Role of endothelin-1/endothelin receptor signaling in fibrosis and calcification in nephrogenic systemic fibrosis, Sei-ichiro Motegi; Etsuko Okada; Akihiko Uchiyama; Kazuya Yamada; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Fumiko Monma; Tamio Suzuki; Osamu Ishikawa, Sep. 2014, EXPERIMENTAL DERMATOLOGY, 23, 9, 664, 669, Scientific journal

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• MFG-E8 Regulates Angiogenesis in Cutaneous Wound Healing, Akihiko Uchiyama; Kazuya Yamada; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Mark C. Udey; Osamu Ishikawa; Sei-ichiro Motegi, Jul. 2014, AMERICAN JOURNAL OF PATHOLOGY, 184, 7, 1981, 1990, Scientific journal

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• No association of atherosclerosis with digital ulcers in Japanese patients with systemic sclerosis: Evaluation of carotid intima-media thickness and plaque characteristics, Sei-ichiro Motegi; Sayaka Toki; Tomoyasu Hattori; Kazuya Yamada; Akihiko Uchiyama; Osamu Ishikawa, Jul. 2014, JOURNAL OF DERMATOLOGY, 41, 7, 604, 608, Scientific journal

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• Blepharochalasis: Possibly associated with matrix metalloproteinases, Sei-ichiro Motegi; Akihiko Uchiyama; Kazuya Yamada; Sachiko Ogino; Yuko Takeuchi; Osamu Ishikawa, Jun. 2014, JOURNAL OF DERMATOLOGY, 41, 6, 536, 538, Scientific journal

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• Involuted facial infantile hemangioma with fatty replacement successfully treated with surgery, Akihiko Uchiyama; Atsushi Tamura; Okada Etsuko; Sei-ichiro Motegi; Osamu Ishikawa, May 2014, JOURNAL OF DERMATOLOGY, 41, 5, 453, 454

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• Persistent prurigo nodularis in HIV-infected patient responsive to antiretroviral therapy with raltegravir, Sei-ichiro Motegi; Madoka Kato; Akihiko Uchiyama; Kazuya Yamada; Akira Shimizu; Hiroo Amano; Osamu Ishikawa, Mar. 2014, JOURNAL OF DERMATOLOGY, 41, 3, 272, 273

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• Case of angioedema and urticaria induced by lenalidomide, Akihiko Uchiyama; Sei-ichiro Motegi; Kazuya Yamada; Akihito Uehara; Osamu Ishikawa, Feb. 2014, JOURNAL OF DERMATOLOGY, 41, 2, 179, 181

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• LEOPARD症候群の2例, 茂木 精一郎; 山田 和哉; 内山 明彦; 上原 顕仁; 横山 洋子; 石川 治, Apr. 2013, 123, 5, 972, Scientific journal
• A Case of Rapidly Progressive, Fatal Mycosis Fungoides Presenting as a Haematoma-like Lesion, Tomoyasu Hattori; Akihiko Uchiyama; Osamu Tago; Yayoi Nagai; Osamu Ishikawa, 2013, ACTA DERMATO-VENEREOLOGICA, 93, 6, 707, 710, Scientific journal

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• Transient acantholytic dermatosis (Grover's disease) with an isolated eruption, Sei-ichiro Motegi; Akihiko Uchiyama; Osamu Ishikawa, 2013, European Journal of Dermatology, 23, 3, 424, 425

  DOI
• MFG-E8 Regulates Angiogenesis in Cutaneous Wound Healing, Uchiyama Akihiko, 2015, The Kitakanto Medical Journal, 65, 1, 119, 120
• The Role of MFG-E8 in Cutaneous Wound Healing: The Effect of MFG-E8 and/or bFGF on Wound Healing, UCHIYAMA Akihiko;YAMADA Kazuya;Perera Buddhini;OGINO Sachiko;YOKOYAMA Yoko;TAKEUCHI Yuko;MOTEGI Sei-ichiro;ISHIKAWA Osamu, 2014, Hifu no kagaku, 13, 22, S13, 18
• No association of atherosclerosis with digital ulcers in Japanese patients with systemic sclerosis: Evaluation of carotid intima-media thickness and plaque characteristics, Motegi, Sei-ichiro;Toki, Sayaka;Hattori, Tomoyasu;Yamada, Kazuya;Uchiyama, Akihiko;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 7, 604, 608

  DOI
• 群馬大学皮膚科通院患者における局所多汗症の有病率と様々な皮膚疾患との関連について, ;;;, May 2023, 133, 5, 1358
• Transient acantholytic dermatosis (Grover's disease) with an isolated eruption, Motegi, Sei-ichiro;Uchiyama, Akihiko;Ishikawa, Osamu, 2013, EUROPEAN JOURNAL OF DERMATOLOGY, 23, 3, 424, 425

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• Norepinephrine-Induced IL-6 Regulates Fibrosis In Systemic Sclerosis, Motegi, Sei-ichiro;Uehara, Akihito;Yamada, Kazuya;Uchiyama, Akihiko;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Ishikawa, Osamu, 2013, ARTHRITIS AND RHEUMATISM, 65, S280, S280
• A Case of Rapidly Progressive, Fatal Mycosis Fungoides Presenting as a Haematoma-like Lesion, Hattori, Tomoyasu;Uchiyama, Akihiko;Tago, Osamu;Nagai, Yayoi;Ishikawa, Osamu, 2013, ACTA DERMATO-VENEREOLOGICA, 93, 6, 707, 710

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• Case of angioedema and urticaria induced by lenalidomide, Uchiyama, Akihiko;Motegi, Sei-ichiro;Yamada, Kazuya;Uehara, Akihito;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 2, 179, 181

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• Persistent prurigo nodularis in HIV-infected patient responsive to antiretroviral therapy with raltegravir, Motegi, Sei-ichiro;Kato, Madoka;Uchiyama, Akihiko;Yamada, Kazuya;Shimizu, Akira;Amano, Hiroo;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 3, 272, 273

  DOI
• Involuted facial infantile hemangioma with fatty replacement successfully treated with surgery, Uchiyama, Akihiko;Tamura, Atsushi;Etsuko, Okada;Motegi, Sei-ichiro;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 5, 453, 454

  DOI
• Blepharochalasis: Possibly associated with matrix metalloproteinases, Motegi, Sei-ichiro;Uchiyama, Akihiko;Yamada, Kazuya;Ogino, Sachiko;Takeuchi, Yuko;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 6, 536, 538

  DOI
• MFG-E8 Regulates Angiogenesis in Cutaneous Wound Healing, Uchiyama, Akihiko;Yamada, Kazuya;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Udey, Mark C.;Ishikawa, Osamu;Motegi, Sei-ichiro, 2014, AMERICAN JOURNAL OF PATHOLOGY, 184, 7, 1981, 1990

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• Role of endothelin-1/endothelin receptor signaling in fibrosis and calcification in nephrogenic systemic fibrosis, Motegi, Sei-ichiro;Okada, Etsuko;Uchiyama, Akihiko;Yamada, Kazuya;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Monma, Fumiko;Suzuki, Tamio;Ishikawa, Osamu, 2014, EXPERIMENTAL DERMATOLOGY, 23, 9, 664, 669

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• Primary Granulocytic Sarcoma of the Skin without Hematologic Disorders, Uchiyama, Akihiko;Motegi, Sei-ichiro;Yamada, Kazuya;Amano, Hiroo;Ishikawa, Osamu, 2014, ANNALS OF DERMATOLOGY, 26, 5, 653, 655

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• THE REGULATION OF MESENCHYMAL STEM CELLS IN MELANOMA BY MFG-E8, Motegi, Sei-Ichiro;Yamada, Kazuya;Uchiyama, Akihiko;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 15, 15
• Elevated plasma homocysteine level is possibly associated with skin sclerosis in a series of Japanese patients with systemic sclerosis, Motegi, Sei-ichiro;Toki, Sayaka;Yamada, Kazuya;Uchiyama, Akihiko;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 11, 986, 991

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• First Japanese case of atypical progeroid syndrome/atypical Werner syndrome with heterozygous LMNA mutation, Motegi, Sei-ichiro;Yokoyama, Yoko;Uchiyama, Akihiko;Ogino, Sachiko;Takeuchi, Yuko;Yamada, Kazuya;Hattori, Tomoyasu;Hashizume, Hiroaki;Ishikawa, Yuichi;Goto, Makoto;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 12, 1047, 1052

  DOI
• Demographic and clinical features of autoimmune thyroid disorder in Japanese patients with systemic sclerosis, Toki, Sayaka;Motegi, Sei-ichiro;Yamada, Kazuya;Uchiyama, Akihiko;Ishikawa, Osamu, 2014, JOURNAL OF DERMATOLOGY, 41, 12, 1053, 1057

  DOI
• Skin Sclerosis with Elevation of Serum Interleukin-6 That Is Possibly Associated with Immunoglobulin 4-Related Disease, Motegi, Sei-ichiro;Uchiyama, Akihiko;Yamada, Kazuya;Uehara, Akihito;Toki, Sayaka;Ishikawa, Osamu, 2014, ANNALS OF DERMATOLOGY, 26, 6, 766, 767

  DOI
• Demographic and clinical features of systemic sclerosis patients with anti-RNA polymerase III antibodies, Motegi, Sei-ichiro;Toki, Sayaka;Yamada, Kazuya;Uchiyama, Akihiko;Ishikawa, Osamu, 2015, JOURNAL OF DERMATOLOGY, 42, 2, 189, 192

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• Clinical and laboratory features of systemic sclerosis complicated with localized scleroderma, Toki, Sayaka;Motegi, Sei-ichiro;Yamada, Kazuya;Uchiyama, Akihiko;Kanai, Sahori;Yamanaka, Masayoshi;Ishikawa, Osamu, 2015, JOURNAL OF DERMATOLOGY, 42, 3, 283, 287

  DOI
• Protective effect of botulinum toxin A after cutaneous ischemia-reperfusion injury, Uchiyama, Akihiko;Yamada, Kazuya;Perera, Buddhini;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Ishikawa, Osamu;Motegi, Sei-ichiro, 2015, SCIENTIFIC REPORTS, 5

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• Protective Effect of MFG-E8 after Cutaneous Ischemia-Reperfusion Injury, Uchiyama, Akihiko;Yamada, Kazuya;Perera, Buddhini;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Ishikawa, Osamu;Motegi, Sei-ichiro, 2015, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 135, 4, 1157, 1165

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• Cutaneous Marginal Zone B-cell Lymphoma Evolving into Anetoderma: A Role of Matrix Metalloproteinases?, Uchiyama, Akihiko;Motegi, Sei-ichiro;Okada, Etsuko;Hirai, Nobuyuki;Nagai, Yayoi;Tamura, Atsushi;Ishikawa, Osamu, 2015, ACTA DERMATO-VENEREOLOGICA, 95, 4, 499, 500

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• Poorly Differentiated Squamous Cell Carcinoma in an Atomic Bomb Survivor, Uchiyama, Akihiko;Motegi, Sei-ichiro;Ishikawa, Osamu, 2015, ANNALS OF DERMATOLOGY, 27, 3, 332, 334

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• Successful treatment of neutrophilic dermatosis in patient with Crohn's disease with granulocyte and monocyte adsorption apheresis, Motegi, Sei-ichiro;Uchiyama, Akihiko;Toki, Sayaka;Yamada, Kazuya;Amano, Hiroo;Ishikawa, Osamu, 2015, JOURNAL OF DERMATOLOGY, 42, 8, 836, 837

  DOI
• Lichen planus complicated with thymoma: Report of three Japanese cases and review of the published work, Motegi, Sei-ichiro;Uchiyama, Akihiko;Yamada, Kazuya;Toki, Sayaka;Amano, Hiroo;Ishikawa, Osamu, 2015, JOURNAL OF DERMATOLOGY, 42, 11, 1072, 1077

  DOI
• Lymphomatoid papulosis associated with follicular B-cell lymphoma in lymph nodes, Uchiyama, Akihiko;Motegi, Sei-ichiro;Ishikawa, Osamu, 2015, JOURNAL OF DERMATOLOGY, 42, 11, 1129, 1130

  DOI
• Pathogenesis of Multiple Lentigines in LEOPARD Syndrome with PTPN11 Gene Mutation, Motegi, Sei-ichiro;Yokoyama, Yoko;Ogino, Sachiko;Yamada, Kazuya;Uchiyama, Akihiko;Perera, Buddhini;Takeuchi, Yuko;Ohnishi, Hiroshi;Ishikawa, Osamu, 2015, ACTA DERMATO-VENEREOLOGICA, 95, 8, 978, 984

  DOI
• Beneficial effect of botulinum toxin A on Raynaud's phenomenon in Japanese patients with systemic sclerosis: A prospective, case series study, Motegi, Sei-ichiro;Yamada, Kazuya;Toki, Sayaka;Uchiyama, Akihiko;Kubota, Yuka;Nakamura, Tetsuya;Ishikawa, Osamu, 2016, JOURNAL OF DERMATOLOGY, 43, 1, 56, 62

  DOI
• Successful Treatment of Multicentric Reticulohistiocytosis with Adalimumab, Prednisolone and Methotrexate, Motegi, Sei-ichiro;Yonemoto, Yukio;Yanagisawa, Shinya;Toki, Sayaka;Uchiyama, Akihiko;Yamada, Kazuya;Ishikawa, Osamu, 2016, ACTA DERMATO-VENEREOLOGICA, 96, 1, 124, 125

  DOI
• Beneficial Effect of Botulinum Toxin-a on Raynaud's Phenomenon in Japanese Patients with Systemic Sclerosis: A Prospective, Open-Label Trial, Motegi, Sei-ichiro;Yamada, Kazuya;Toki, Sayaka;Uchiyama, Akihiko;Nakamura, Tetsuya;Ishikawa, Osamu, 2015, ARTHRITIS & RHEUMATOLOGY, 67
• Reply: "Erosive oral lichen planus as a sign of paraneoplastic pemphigus", Motegi, Sei-ichiro;Uchiyama, Akihiko;Toki, Sayaka;Yamada, Kazuya;Amano, Hiroo;Ishikawa, Osamu, 2016, JOURNAL OF DERMATOLOGY, 43, 8, 984, 984

  DOI
• MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell-Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages, Yamada, Kazuya;Uchiyama, Akihiko;Uehara, Akihito;Perera, Buddhini;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Udey, Mark C.;Ishikawa, Osamu;Motegi, Sei-ichiro, 2016, CANCER RESEARCH, 76, 14, 4283, 4292

  DOI
• Mechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis, Uehara, Akihito;Motegi, Sei-ichiro;Yamada, Kazuya;Uchiyama, Akihiko;Perera, Buddhini;Toki, Sayaka;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Ishikawa, Osamu, 2016, SCIENTIFIC REPORTS, 6

  DOI
• Increased susceptibility to oxidative stress- and ultraviolet A-induced apoptosis in fibroblasts in atypical progeroid syndrome/atypical Werner syndrome with LMNA mutation, Motegi, Sei-ichiro;Uchiyama, Akihiko;Yamada, Kazuya;Ogino, Sachiko;Yokoyama, Yoko;Perera, Buddhini;Takeuchi, Yuko;Ishikawa, Osamu, 2016, EXPERIMENTAL DERMATOLOGY, 25, 20, 27

  DOI
• Topical betamethasone butyrate propionate exacerbates pressure ulcers after cutaneous ischemia-reperfusion injury, Uchiyama, Akihiko;Yamada, Kazuya;Perera, Buddhini;Ogino, Sachiko;Yokoyama, Yoko;Takeuchi, Yuko;Ishikawa, Osamu;Motegi, Sei-ichiro, 2016, EXPERIMENTAL DERMATOLOGY, 25, 9, 678, 683

  DOI
• Angioinvasive lymphomatoid papulosis (type E): a first Japanese case, Uchiyama, Akihiko;Motegi, Sei-ichiro;Ishikawa, Osamu, 2016, EUROPEAN JOURNAL OF DERMATOLOGY, 26, 5, 507, 508

  DOI
• Mesenchymal stem cells-derived MFG-E8 accelerates diabetic cutaneous wound healing, Uchiyama, Akihiko;Motegi, Sei-ichiro;Sekiguchi, Akiko;Fujiwara, Chisako;Perera, Buddhini;Ogino, Sachiko;Yokoyama, Yoko;Ishikawa, Osamu, 2017, JOURNAL OF DERMATOLOGICAL SCIENCE, 86, 3, 187, 197

  DOI
• Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress, Motegi, Sei-ichiro;Sekiguchi, Akiko;Uchiyama, Akihiko;Uehara, Akihito;Fujiwara, Chisako;Yamazaki, Sahori;Perera, Buddhini;Nakamura, Hideharu;Ogino, Sachiko;Yokoyama, Yoko;Akai, Ryoko;Iwawaki, Takao;Ishikawa, Osamu, 2017, SCIENTIFIC REPORTS, 7

  DOI
• Trigeminal trophic syndrome: Analysis of the number of peripheral nerve fibres and blood vessels in the lesional skin, Uchiyama, Akihiko;Motegi, Sei-ichiro;Fujiwara, Chisako;Sekiguchi, Akiko;Yasuda, Masahito;Amano, Hiroo;Ishikawa, Osamu, 2018, AUSTRALASIAN JOURNAL OF DERMATOLOGY, 59, 1, 59, 61

  DOI
• Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress, Sekiguchi, Akiko;Motegi, Sei-ichiro;Uchiyama, Akihiko;Uehara, Akihito;Fujiwara, Chisako;Yamazaki, Sahori;Perera, Buddhini;Nakamura, Hideharu;Ogino, Sachiko;Yokoyama, Yoko;Akai, Ryoko;Iwawaki, Takao;Ishikawa, Osamu, 2018, JOURNAL OF DERMATOLOGICAL SCIENCE, 90, 2, 144, 153

  DOI
• Inhibitory Regulation of Skin Fibrosis in Systemic Sclerosis by Apelin/APJ Signaling, Yokoyama, Yoko;Sekiguchi, Akiko;Fujiwara, Chisako;Uchiyama, Akihiko;Uehara, Akihito;Ogino, Sachiko;Torii, Ryoko;Ishikawa, Osamu;Motegi, Sei-ichiro, 2018, ARTHRITIS & RHEUMATOLOGY, 70, 10, 1661, 1672

  DOI
• Suppressive Regulation by MFG-E8 of Latent Transforming Growth Factor β-Induced Fibrosis via Binding to αv Integrin: Significance in the Pathogenesis of Fibrosis in Systemic Sclerosis, Fujiwara, Chisako;Uehara, Akihito;Sekiguchi, Akiko;Uchiyama, Akihiko;Yamazaki, Sahori;Ogino, Sachiko;Yokoyama, Yoko;Torii, Ryoko;Hosoi, Mari;Suto, Chiaki;Tsunekawa, Katsuhiko;Murakami, Masami;Ishikawa, Osamu;Motegi, Sei-ichiro, 2019, ARTHRITIS & RHEUMATOLOGY, 71, 2, 302, 314

  DOI
• The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y₂ Purinergic Receptor, Perera, Liyanage Manosika Buddhini;Sekiguchi, Akiko;Uchiyama, Akihiko;Uehara, Akihito;Fujiwara, Chisako;Yamazaki, Sahori;Yokoyama, Yoko;Ogino, Sachiko;Torii, Ryoko;Hosoi, Mari;Ishikawa, Osamu;Motegi, Sei-ichiro, 2019, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 139, 4, 890, 899

  DOI
• Inhibitory effect of kaempferol on skin fibrosis in systemic sclerosis by the suppression of oxidative stress, Sekiguchi, Akiko;Motegi, Sei-ichiro;Fujiwara, Chisako;Yamazaki, Sahori;Inoue, Yuta;Uchiyama, Akihiko;Akai, Ryoko;Iwawaki, Takao;Ishikawa, Osamu, 2019, JOURNAL OF DERMATOLOGICAL SCIENCE, 96, 1, 8, 17

  DOI
• Protective effect of dimethyl fumarate for the development of pressure ulcers after cutaneous ischemia-reperfusion injury, Inoue, Yuta;Uchiyama, Akihiko;Sekiguchi, Akiko;Yamazaki, Sahori;Fujiwara, Chisako;Yokoyama, Yoko;Ogino, Sachiko;Torii, Ryoko;Hosoi, Mari;Akai, Ryoko;Iwawaki, Takao;Ishikawa, Osamu;Motegi, Sei-ichiro, 2020, WOUND REPAIR AND REGENERATION, 28, 5, 600, 608

  DOI
• Prevalence and clinical characteristics of earlobe crease in systemic sclerosis: Possible association with vascular dysfunction, Sekiguchi, Akiko;Inoue, Yuta;Yamazaki, Sahori;Uchiyama, Akihiko;Ishikawa, Osamu;Kuribayashi, Shiko;Uraoka, Toshio;Hara, Kenichiro;Yamaguchi, Kouichi;Maeno, Toshitaka;Uchida, Mitsuo;Koyama, Hiroshi;Motegi, Sei-Ichiro, 2020, JOURNAL OF DERMATOLOGY, 47, 8, 870, 875

  DOI
• Demographic and clinical characteristics of cytomegalovirus reactivation in dermatomyositis, Sekiguchi, Akiko;Inoue, Yuta;Yamazaki, Sahori;Uchiyama, Akihiko;Endo, Yukie;Ishikawa, Osamu;Motegi, Sei-ichiro, 2020, JOURNAL OF DERMATOLOGY, 47, 8, 876, 881

  DOI
• Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model, Yamazaki, Sahori;Sekiguchi, Akiko;Uchiyama, Akihiko;Fujiwara, Chisako;Inoue, Yuta;Yokoyama, Yoko;Ogino, Sachiko;Torii, Ryoko;Hosoi, Mari;Akai, Ryoko;Iwawaki, Takao;Ishikawa, Osamu;Motegi, Sei-ichiro, 2020, SCIENTIFIC REPORTS, 10, 1

  DOI
• Plasma homocysteine levels are positively associated with interstitial lung disease in dermatomyositis patients with anti-aminoacyl-tRNA synthetase antibody, Sekiguchi, Akiko;Endo, Yukie;Yamazaki, Sahori;Uchiyama, Akihiko;Shimizu, Akira;Motegi, Sei-ichiro, 2021, JOURNAL OF DERMATOLOGY, 48, 1, 34, 41

  DOI
• Suppression of neuropeptide by botulinum toxin improves imiquimod-induced psoriasis-like dermatitis via the regulation of neuroimmune system, Amalia, Syahla Nisaa;Uchiyama, Akihiko;Baral, Hritu;Inoue, Yuta;Yamazaki, Sahori;Fujiwara, Chisako;Sekiguchi, Akiko;Yokoyama, Yoko;Ogino, Sachiko;Torii, Ryoko;Hosoi, Mari;Ishikawa, Osamu;Motegi, Sei-ichiro, 2021, JOURNAL OF DERMATOLOGICAL SCIENCE, 101, 1, 58, 68

  DOI
• A case of coexisting Bowen's disease and cutaneous pseudolymphoma, Uchiyama, Akihiko;Kishi, Chikako;Kuriyama, Yuko;Shimizu, Akira;Ishikawa, Osamu;Motegi, Sei-ichiro, 2020, EUROPEAN JOURNAL OF DERMATOLOGY, 30, 6, 744, 746

  DOI
• Inhibition of skin fibrosis in systemic sclerosis by botulinum toxin B via the suppression of oxidative stress, Baral, Hritu;Sekiguchi, Akiko;Uchiyama, Akihiko;Amalia, Syahla Nisaa;Yamazaki, Sahori;Inoue, Yuta;Yokoyama, Yoko;Ogino, Sachiko;Torii, Ryoko;Hosoi, Mari;Akai, Ryoko;Iwawaki, Takao;Ishikawa, Osamu;Motegi, Sei-ichiro, 2021, JOURNAL OF DERMATOLOGY, 48, 7, 1052, 1061

  DOI
• Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway, Bajpai, Deepti;Mehdizadeh, Spencer;Uchiyama, Akihiko;Inoue, Yuta;Sawaya, Andrew;Overmiller, Andrew;Brooks, Stephen R.;Hasneen, Kowser;Kellett, Meghan;Palazzo, Elisabetta;Motegi, Sei-ichiro;Yuspa, Stuart H.;Cataisson, Christophe;Morasso, Maria, I, 2021, ONCOGENE, 40, 21, 3680, 3694

  DOI
• Anti-polymyositis/Scl antibody-positive overlap syndrome of diffuse cutaneous systemic sclerosis, dermatomyositis, systemic lupus erythematosus, and antiphospholipid syndrome, Saito, Shintaro;Endo, Yukie;Nishio, Mayu;Uchiyama, Akihiko;Uehara, Akihito;Toki, Sayaka;Yasuda, Masahito;Ishikawa, Osamu;Muro, Yoshinao;Motegi, Sei-ichiro, 2022, JOURNAL OF DERMATOLOGY, 49, 2, 294, 298

  DOI
• Antifibrotic effects and mechanisms of mesenchymal stem cell-derived exosomes in a systemic sclerosis mouse model: Possible contribution of miR-196b-5p, Baral, Hritu;Uchiyama, Akihiko;Yokoyama, Yoko;Sekiguchi, Akiko;Yamazaki, Sahori;Amalia, Syahla Nisaa;Inoue, Yuta;Ogino, Sachiko;Torii, Ryoko;Hosoi, Mari;Matsuzaki, Toshiyuki;Motegi, Sei-ichiro, 2021, JOURNAL OF DERMATOLOGICAL SCIENCE, 104, 1, 39, 47

  DOI
• Spontaneous pneumomediastinum developed after steroid pulse therapy in diffuse cutaneous systemic sclerosis patient: A case report, Endo, Yukie;Kim, Jain;Uchiyama, Akihiko;Yasuda, Masahito;Hara, Kenichiro;Motegi, Sei-ichiro, 2022, JOURNAL OF DERMATOLOGY, 49, 6, E185, E186

  DOI
• Tumor suppressive effect of anti-PD-1 antibody against angiosarcoma in a mouse model, Sekiguchi, Akiko;Ishikawa, Mai;Fujiwara, Chisako;Inoue, Yuta;Yamazaki, Sahori;Uchiyama, Akihiko;Motegi, Sei-ichiro, 2022, JOURNAL OF DERMATOLOGICAL SCIENCE, 105, 1, 58, 60

  DOI
• Real-world effectiveness and safety of baricitinib in Japanese patients with atopic dermatitis: A single-center retrospective study, Uchiyama, Akihiko;Fujiwara, Chisako;Inoue, Yuta;Motegi, Sei-ichiro, 2022, JOURNAL OF DERMATOLOGY, 49, 4, 469, 471

  DOI
• Possible suppressive effects of tranilast on NLRP3 inflammasome activation in necrobiosis lipoidica, Uchiyama, Akihiko;Kosaka, Keiji;Okada, Katsuyuki;Motegi, Sei-ichiro, 2022, JOURNAL OF DERMATOLOGY, 49, 12, E433, E434

  DOI
• Possible suppressive effects of baricitinib on serum IL-22 levels in atopic dermatitis, Uchiyama, Akihiko;Fujiwara, Chisako;Inoue, Yuta;Ishikawa, Mai;Motegi, Sei-ichiro, 2022, JOURNAL OF DERMATOLOGICAL SCIENCE, 106, 3, 189, 192

  DOI
• Real-world effectiveness and safety of bosentan in Japanese patients with systemic sclerosis: A single-center retrospective study, Ishikawa, Mai;Endo, Yukie;Yamazaki, Sahori;Sekiguchi, Akiko;Uchiyama, Akihiko;Motegi, Sei-ichiro, 2023, JOURNAL OF DERMATOLOGY, 50, 6, 828, 832

  DOI
• Capillaroscopy in Pigmented Basal Cell Carcinoma Smaller than 3-mm Diameter: A Report of Four Lesions, Saito, Shintaro;Kuriyama, Yuko;Uchiyama, Akihiko;Yasuda, Masahito;Motegi, Sei-ichiro, 2022, ACTA DERMATO-VENEREOLOGICA, 102

  DOI
• Real-world effectiveness and safety of upadacitinib in Japanese patients with atopic dermatitis: a two-centre retrospective study, Kosaka, Keiji;Uchiyama, Akihiko;Ishikawa, Mai;Watanabe, Goichi;Motegi, Sei-ichiro, 2022, EUROPEAN JOURNAL OF DERMATOLOGY, 32, 6, 800, 802

  DOI
• Case report: further delineation of AEBP1-related Ehlers-Danlos Syndrome (classical-like EDS type 2) in an additional patient and comprehensive clinical and molecular review of the literature, Yamaguchi, Tomomi;Hayashi, Shujiro;Nagai, So;Uchiyama, Akihiko;Motegi, Sei-Ichiro;Fujikawa, Tomomi;Takiguchi, Yuri;Kosho, Tomoki, 2023, FRONTIERS IN GENETICS, 14

  DOI
• G蛋白質共役型受容体APJに対するバイアス型アゴニストは酸化ストレス障害を抑制して褥瘡の発生を予防する, ;;;;, Aug. 2019, 69, 3, 295
• 皮膚虚血再灌流障害(急性期褥瘡)に対する転写因子SOX2による制御機構及び新規治療法の開発, ;;;, May 2020, 130, 5, 1262
• 群大病院における褥瘡対策チームの取り組み　亜鉛欠乏に注目して, ;;;;;;;, Jun. 2020, 130, 7, 1671
• 口腔粘膜上皮に高発現する転写因子SOX2による皮膚創傷治癒の制御機構の解明, ;;;;, Sep. 2020, 52回, 51
• 抗酸化薬フマル酸ジメチルによる褥瘡の予防効果の検討, ;;;;;;;;, Aug. 2020, 70, 3, 293
• 筋萎縮性側索硬化症(ALS)モデルマウス(SOD1-G93A)における皮膚虚血再灌流障害(急性期褥瘡)の検討, ;;;;;;;;;;, Aug. 2020, 70, 3, 299
• 血漿交換療法を行った間質性肺炎合併抗MDA5抗体陽性皮膚筋炎の1例, ;;;;;;, Apr. 2021, 38, 2, 336
• アニサキスによるアナフィラキシーの2例, ;;;;;;;;;, May 2021, 131, 5, 1387
• 皮膚虚血再灌流障害(急性期褥瘡)に対する転写因子SOX2による制御機構及び新規治療法の開発, ;;;, May 2021, 131, 5, 1428
• 皮膚創傷治癒のメカニズムについて, 内山 明彦, Aug. 2021, 23, 3, 199
• 【急性期褥瘡の発生機序と治療・ケアのコツ】急性期褥瘡が発生するメカニズムに迫る, 内山 明彦, Jun. 2021, 9, 6, 19
• 転写因子SOX2による皮膚虚血再灌流障害(急性期褥瘡)における制御機構の解明および新規治療法の開発, 内山 明彦, Sep. 2021, 29, 77
• 食物依存性運動誘発アナフィラキシーが疑われた減汗性コリン性蕁麻疹の1例, ;;;;;;;;, Nov. 2021, 125, 11, 1611
• 皮下脂肪織炎様の臨床像を呈したIntravascular large B-cell lymphoma(IVL)の1例, ;;;;, Jan. 2022, 132, 1, 99
• ジアフェニルスルホン(DDS)による薬剤性過敏症症候群の1例　DDSで副作用を生じた5例のHLA解析を含めて, ;;;;;;, Jan. 2022, 132, 1, 99
• ステロイド投与中に縦隔気腫を合併した抗RNAポリメラーゼIII抗体陽性全身性強皮症の1例, ;;;;;, Nov. 2021, 51回, 200
• 毛細血管拡張を伴った剣創状強皮症に対する治療経験のまとめ, ;;;;;;;, Nov. 2021, 51回, 221
• Transient neonatal zinc deficiency(TNZD)の1例, ;;;, Apr. 2022, 132, 4, 665
• Transient neonatal zinc deficiency(TNZD)の1例, ;;;, May 2022, 132, 5, 1303
• 頭痛、腹痛症状から診断に至った遺伝性血管性浮腫の1例, ;;, Aug. 2022, 84, 4, 370
• 【シン・アレルギー診療　プライマリ・ケア領域のアレルギーアップデート】薬物療法　皮膚外用薬, 内山 明彦, Oct. 2022, 104, 10, 1217
• 腫瘍3mm未満の基底細胞癌におけるCapillaroscopy所見の検討, ;;;;;;;;, Sep. 2022, 26, 2, 49
• 天疱瘡に対する免疫グロブリン大量静注療法　自験例9例のまとめ, ;;;;, Oct. 2022, 84, 5, 468
• 血液浄化療法が有効であったバンコマイシン誘発型TEN様線状IgA水疱性皮膚症の1例, ;;;;;, Feb. 2023, 133, 2, 258
• 液体窒素療法における効果的な実施方法の検討　酸化ストレスと組織炎症の関与について, ;;;;;, Aug. 2022, 72, 3, 315
• 温度感受性TRPV4チャネルによる皮膚創傷治癒の制御機構の解明, ;;;;;;;, Aug. 2022, 72, 3, 323
• アトピー性皮膚炎におけるバリシチニブの治療効果とサイトカインへの影響, ;;, Dec. 2022, 84, 6, 578
• 【フレッシャーズ特集:皮膚科の基本マニュアル】(Part2)学会発表・研究・論文　英語の論文の書き方, ;, Mar. 2023, 22, 4, 369
• 腫瘍径3mm未満の基底細胞癌におけるCapillaroscopy所見の検討, ;;;;;;;;, Jun. 2023, 27, 1, 78
• 眼部帯状疱疹後に対側の眼窩尖端症候群を来した53歳男性例, ;;;;;;, Mar. 2023, 63, 3, 180
• QOL向上を目指すHAE治療戦略とは　遺伝性血管性浮腫はNear Normal Lifeを目指す時代に, 内山 明彦, May 2023, 133, 5, 1311
• 抗SMN抗体陽性びまん皮膚硬化型全身性強皮症,多発性筋炎のオーバーラップ症候群の1例, ;;;;;;;, May 2023, 133, 5, 1357
• 群馬大学皮膚科通院患者における局所多汗症の有病率と様々な皮膚疾患との関連について, ;;;, May 2023, 133, 5, 1358
• A case of rapidly progressive, fatal mycosis fungoides presenting as a haematoma-like lesion., Hattori Tomoyasu;Uchiyama Akihiko;Tago Osamu;Nagai Yayoi;Ishikawa Osamu, Acta dermato-venereologica, 93, 6

  DOI
• Transient acantholytic dermatosis (Grover's disease) with an isolated eruption., Motegi Sei-ichiro;Uchiyama Akihiko;Ishikawa Osamu, European journal of dermatology : EJD, 23, 3

  DOI
• Case of angioedema and urticaria induced by lenalidomide., Uchiyama Akihiko;Motegi Sei-Ichiro;Yamada Kazuya;Uehara Akihito;Ishikawa Osamu, Jan. 2014, The Journal of dermatology, 41, 2

  DOI
• Persistent prurigo nodularis in HIV-infected patient responsive to antiretroviral therapy with raltegravir., Motegi Sei-ichiro;Kato Madoka;Uchiyama Akihiko;Yamada Kazuya;Shimizu Akira;Amano Hiroo;Ishikawa Osamu, Jan. 2014, The Journal of dermatology, 41, 3

  DOI
• Involuted facial infantile hemangioma with fatty replacement successfully treated with surgery., Uchiyama Akihiko;Tamura Atsushi;Etsuko Okada;Motegi Sei-ichiro;Ishikawa Osamu, Apr. 2014, The Journal of dermatology, 41, 5

  DOI
• Blepharochalasis: possibly associated with matrix metalloproteinases., Motegi Sei-ichiro;Uchiyama Akihiko;Yamada Kazuya;Ogino Sachiko;Takeuchi Yuko;Ishikawa Osamu, May 2014, The Journal of dermatology, 41, 6

  DOI
• MFG-E8 regulates angiogenesis in cutaneous wound healing., Uchiyama Akihiko;Yamada Kazuya;Ogino Sachiko;Yokoyama Yoko;Takeuchi Yuko;Udey Mark C;Ishikawa Osamu;Motegi Sei-ichiro, May 2014, The American journal of pathology, 184, 7

  DOI
• No association of atherosclerosis with digital ulcers in Japanese patients with systemic sclerosis: evaluation of carotid intima-media thickness and plaque characteristics., Motegi Sei-Ichiro;Toki Sayaka;Hattori Tomoyasu;Yamada Kazuya;Uchiyama Akihiko;Ishikawa Osamu, Jun. 2014, The Journal of dermatology, 41, 7

  DOI
• Role of endothelin-1/endothelin receptor signaling in fibrosis and calcification in nephrogenic systemic fibrosis., Motegi Sei-Ichiro;Okada Etsuko;Uchiyama Akihiko;Yamada Kazuya;Ogino Sachiko;Yokoyama Yoko;Takeuchi Yuko;Monma Fumiko;Suzuki Tamio;Ishikawa Osamu, Experimental dermatology, 23, 9

  DOI
• Elevated plasma homocysteine level is possibly associated with skin sclerosis in a series of Japanese patients with systemic sclerosis., Motegi Sei-Ichiro;Toki Sayaka;Yamada Kazuya;Uchiyama Akihiko;Ishikawa Osamu, Oct. 2014, The Journal of dermatology, 41, 11

  DOI
• Primary Granulocytic Sarcoma of the Skin without Hematologic Disorders., Uchiyama Akihiko;Motegi Sei-Ichiro;Yamada Kazuya;Amano Hiroo;Ishikawa Osamu, Sep. 2014, Annals of dermatology, 26, 5

  DOI
• First Japanese case of atypical progeroid syndrome/atypical Werner syndrome with heterozygous LMNA mutation., Motegi Sei-ichiro;Yokoyama Yoko;Uchiyama Akihiko;Ogino Sachiko;Takeuchi Yuko;Yamada Kazuya;Hattori Tomoyasu;Hashizume Hiroaki;Ishikawa Yuichi;Goto Makoto;Ishikawa Osamu, Oct. 2014, The Journal of dermatology, 41, 12

  DOI
• Cutaneous marginal zone B-cell lymphoma evolving into anetoderma: a role of matrix metalloproteinases?, Uchiyama Akihiko;Motegi Sei-ichiro;Okada Etsuko;Hirai Nobuyuki;Nagai Yayoi;Tamura Atsushi;Ishikawa Osamu, Acta dermato-venereologica, 95, 4

  DOI
• Demographic and clinical features of autoimmune thyroid disorder in Japanese patients with systemic sclerosis., Toki Sayaka;Motegi Sei-ichiro;Yamada Kazuya;Uchiyama Akihiko;Ishikawa Osamu, Nov. 2014, The Journal of dermatology, 41, 12

  DOI
• Skin sclerosis with elevation of serum interleukin-6 that is possibly associated with immunoglobulin 4-related disease., Motegi Sei-Ichiro;Uchiyama Akihiko;Yamada Kazuya;Uehara Akihito;Toki Sayaka;Ishikawa Osamu, Nov. 2014, Annals of dermatology, 26, 6

  DOI
• Demographic and clinical features of systemic sclerosis patients with anti-RNA polymerase III antibodies., Motegi Sei-Ichiro;Toki Sayaka;Yamada Kazuya;Uchiyama Akihiko;Ishikawa Osamu, Dec. 2014, The Journal of dermatology, 42, 2

  DOI
• Protective effect of MFG-E8 after cutaneous ischemia-reperfusion injury., Uchiyama Akihiko;Yamada Kazuya;Perera Buddhini;Ogino Sachiko;Yokoyama Yoko;Takeuchi Yuko;Ishikawa Osamu;Motegi Sei-Ichiro, Dec. 2014, The Journal of investigative dermatology, 135, 4

  DOI
• Clinical and laboratory features of systemic sclerosis complicated with localized scleroderma., Toki Sayaka;Motegi Sei-ichiro;Yamada Kazuya;Uchiyama Akihiko;Kanai Sahori;Yamanaka Masayoshi;Ishikawa Osamu, Jan. 2015, The Journal of dermatology, 42, 3

  DOI
• Protective effect of botulinum toxin A after cutaneous ischemia-reperfusion injury., Uchiyama Akihiko;Yamada Kazuya;Perera Buddhini;Ogino Sachiko;Yokoyama Yoko;Takeuchi Yuko;Ishikawa Osamu;Motegi Sei-Ichiro, Mar. 2015, Scientific reports, 5

  DOI
• Successful treatment of neutrophilic dermatosis in patient with Crohn's disease with granulocyte and monocyte adsorption apheresis., Motegi Sei-ichiro;Uchiyama Akihiko;Toki Sayaka;Yamada Kazuya;Amano Hiroo;Ishikawa Osamu, Apr. 2015, The Journal of dermatology, 42, 8

  DOI
• Pathogenesis of multiple lentigines in LEOPARD syndrome with PTPN11 gene mutation., Motegi Sei-Ichiro;Yokoyama Yoko;Ogino Sachiko;Yamada Kazuya;Uchiyama Akihiko;Perera Buddhini;Takeuchi Yuko;Ohnishi Hiroshi;Ishikawa Osamu, Acta dermato-venereologica, 95, 8

  DOI
• Successful Treatment of Multicentric Reticulohistiocytosis with Adalimumab, Prednisolone and Methotrexate., Motegi Sei-Ichiro;Yonemoto Yukio;Yanagisawa Shinya;Toki Sayaka;Uchiyama Akihiko;Yamada Kazuya;Ishikawa Osamu, Acta dermato-venereologica, 96, 1

  DOI
• Lichen planus complicated with thymoma: Report of three Japanese cases and review of the published work., Motegi Sei-Ichiro;Uchiyama Akihiko;Yamada Kazuya;Toki Sayaka;Amano Hiroo;Ishikawa Osamu, Jun. 2015, The Journal of dermatology, 42, 11

  DOI
• Poorly Differentiated Squamous Cell Carcinoma in an Atomic Bomb Survivor., Uchiyama Akihiko;Motegi Sei-Ichiro;Ishikawa Osamu, May 2015, Annals of dermatology, 27, 3

  DOI
• Beneficial effect of botulinum toxin A on Raynaud's phenomenon in Japanese patients with systemic sclerosis: A prospective, case series study., Motegi Sei-ichiro;Yamada Kazuya;Toki Sayaka;Uchiyama Akihiko;Kubota Yuka;Nakamura Tetsuya;Ishikawa Osamu, Jul. 2015, The Journal of dermatology, 43, 1

  DOI
• Lymphomatoid papulosis associated with follicular B-cell lymphoma in lymph nodes., Uchiyama Akihiko;Motegi Sei-ichiro;Ishikawa Osamu, Aug. 2015, The Journal of dermatology, 42, 11

  DOI
• Reply: "Erosive oral lichen planus as a sign of paraneoplastic pemphigus"., Motegi Sei-Ichiro;Uchiyama Akihiko;Toki Sayaka;Yamada Kazuya;Amano Hiroo;Ishikawa Osamu, Feb. 2016, The Journal of dermatology, 43, 8

  DOI
• Topical betamethasone butyrate propionate exacerbates pressure ulcers after cutaneous ischemia-reperfusion injury., Uchiyama Akihiko;Yamada Kazuya;Perera Buddhini;Ogino Sachiko;Yokoyama Yoko;Takeuchi Yuko;Ishikawa Osamu;Motegi Sei-Ichiro, Jun. 2016, Experimental dermatology, 25, 9

  DOI
• MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell-Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages., Yamada Kazuya;Uchiyama Akihiko;Uehara Akihito;Perera Buddhini;Ogino Sachiko;Yokoyama Yoko;Takeuchi Yuko;Udey Mark C;Ishikawa Osamu;Motegi Sei-Ichiro, May 2016, Cancer research, 76, 14

  DOI
• Angioinvasive lymphomatoid papulosis (type E): a first Japanese case., Uchiyama Akihiko;Motegi Sei-Ichiro;Ishikawa Osamu, European journal of dermatology : EJD, 26, 5

  DOI
• Increased susceptibility to oxidative stress- and ultraviolet A-induced apoptosis in fibroblasts in atypical progeroid syndrome/atypical Werner syndrome with LMNA mutation., Motegi Sei-Ichiro;Uchiyama Akihiko;Yamada Kazuya;Ogino Sachiko;Yokoyama Yoko;Perera Buddhini;Takeuchi Yuko;Ishikawa Osamu, Experimental dermatology, 25 Suppl 3

  DOI
• Mechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis., Uehara Akihito;Motegi Sei-Ichiro;Yamada Kazuya;Uchiyama Akihiko;Perera Buddhini;Toki Sayaka;Ogino Sachiko;Yokoyama Yoko;Takeuchi Yuko;Ishikawa Osamu, Sep. 2016, Scientific reports, 6

  DOI
• Mesenchymal stem cells-derived MFG-E8 accelerates diabetic cutaneous wound healing., Uchiyama Akihiko;Motegi Sei-Ichiro;Sekiguchi Akiko;Fujiwara Chisako;Perera Buddhini;Ogino Sachiko;Yokoyama Yoko;Ishikawa Osamu, Mar. 2017, Journal of dermatological science, 86, 3

  DOI
• Trigeminal trophic syndrome: Analysis of the number of peripheral nerve fibres and blood vessels in the lesional skin., Uchiyama Akihiko;Motegi Sei-Ichiro;Fujiwara Chisako;Sekiguchi Akiko;Yasuda Masahito;Amano Hiroo;Ishikawa Osamu, Jul. 2017, The Australasian journal of dermatology, 59, 1

  DOI
• Protective effect of mesenchymal stem cells on the pressure ulcer formation by the regulation of oxidative and endoplasmic reticulum stress., Motegi Sei-Ichiro;Sekiguchi Akiko;Uchiyama Akihiko;Uehara Akihito;Fujiwara Chisako;Yamazaki Sahori;Perera Buddhini;Nakamura Hideharu;Ogino Sachiko;Yokoyama Yoko;Akai Ryoko;Iwawaki Takao;Ishikawa Osamu, Dec. 2017, Scientific reports, 7, 1

  DOI
• Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress., Sekiguchi Akiko;Motegi Sei-Ichiro;Uchiyama Akihiko;Uehara Akihito;Fujiwara Chisako;Yamazaki Sahori;Perera Buddhini;Nakamura Hideharu;Ogino Sachiko;Yokoyama Yoko;Akai Ryoko;Iwawaki Takao;Ishikawa Osamu, Journal of dermatological science, 90, 2

  DOI
• Inhibitory Regulation of Skin Fibrosis in Systemic Sclerosis by Apelin/APJ Signaling., Yokoyama Yoko;Sekiguchi Akiko;Fujiwara Chisako;Uchiyama Akihiko;Uehara Akihito;Ogino Sachiko;Torii Ryoko;Ishikawa Osamu;Motegi Sei-Ichiro, Aug. 2018, Arthritis & rheumatology (Hoboken, N.J.), 70, 10

  DOI
• Suppressive Regulation by MFG-E8 of Latent Transforming Growth Factor β-Induced Fibrosis via Binding to αv Integrin: Significance in the Pathogenesis of Fibrosis in Systemic Sclerosis., Fujiwara Chisako;Uehara Akihito;Sekiguchi Akiko;Uchiyama Akihiko;Yamazaki Sahori;Ogino Sachiko;Yokoyama Yoko;Torii Ryoko;Hosoi Mari;Suto Chiaki;Tsunekawa Katsuhiko;Murakami Masami;Ishikawa Osamu;Motegi Sei-Ichiro, Jan. 2019, Arthritis & rheumatology (Hoboken, N.J.), 71, 2

  DOI
• The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y2 Purinergic Receptor., Perera Liyanage Manosika Buddhini;Sekiguchi Akiko;Uchiyama Akihiko;Uehara Akihito;Fujiwara Chisako;Yamazaki Sahori;Yokoyama Yoko;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Ishikawa Osamu;Motegi Sei-Ichiro, Nov. 2018, The Journal of investigative dermatology, 139, 4

  DOI
• Inhibitory effect of kaempferol on skin fibrosis in systemic sclerosis by the suppression of oxidative stress., Sekiguchi Akiko;Motegi Sei-Ichiro;Fujiwara Chisako;Yamazaki Sahori;Inoue Yuta;Uchiyama Akihiko;Akai Ryoko;Iwawaki Takao;Ishikawa Osamu, Aug. 2019, Journal of dermatological science, 96, 1

  DOI
• Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model., Yamazaki Sahori;Sekiguchi Akiko;Uchiyama Akihiko;Fujiwara Chisako;Inoue Yuta;Yokoyama Yoko;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Akai Ryoko;Iwawaki Takao;Ishikawa Osamu;Motegi Sei-Ichiro, Jan. 2020, Scientific reports, 10, 1

  DOI
• Protective effect of dimethyl fumarate for the development of pressure ulcers after cutaneous ischemia-reperfusion injury., Inoue Yuta;Uchiyama Akihiko;Sekiguchi Akiko;Yamazaki Sahori;Fujiwara Chisako;Yokoyama Yoko;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Akai Ryoko;Iwawaki Takao;Ishikawa Osamu;Motegi Sei-Ichiro, May 2020, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 28, 5

  DOI
• Prevalence and clinical characteristics of earlobe crease in systemic sclerosis: Possible association with vascular dysfunction., Sekiguchi Akiko;Inoue Yuta;Yamazaki Sahori;Uchiyama Akihiko;Ishikawa Osamu;Kuribayashi Shiko;Uraoka Toshio;Hara Kenichiro;Yamaguchi Kouichi;Maeno Toshitaka;Uchida Mitsuo;Koyama Hiroshi;Motegi Sei-Ichiro, May 2020, The Journal of dermatology, 47, 8

  DOI
• Demographic and clinical characteristics of cytomegalovirus reactivation in dermatomyositis., Sekiguchi Akiko;Inoue Yuta;Yamazaki Sahori;Uchiyama Akihiko;Endo Yukie;Ishikawa Osamu;Motegi Sei-Ichiro, May 2020, The Journal of dermatology, 47, 8

  DOI
• Plasma homocysteine levels are positively associated with interstitial lung disease in dermatomyositis patients with anti-aminoacyl-tRNA synthetase antibody., Sekiguchi Akiko;Endo Yukie;Yamazaki Sahori;Uchiyama Akihiko;Shimizu Akira;Motegi Sei-Ichiro, Sep. 2020, The Journal of dermatology, 48, 1

  DOI
• Suppression of neuropeptide by botulinum toxin improves imiquimod-induced psoriasis-like dermatitis via the regulation of neuroimmune system., Amalia Syahla Nisaa;Uchiyama Akihiko;Baral Hritu;Inoue Yuta;Yamazaki Sahori;Fujiwara Chisako;Sekiguchi Akiko;Yokoyama Yoko;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Ishikawa Osamu;Motegi Sei-Ichiro, Nov. 2020, Journal of dermatological science, 101, 1

  DOI
• A case of coexisting Bowen's disease and cutaneous pseudolymphoma., Uchiyama Akihiko;Kishi Chikako;Kuriyama Yuko;Shimizu Akira;Ishikawa Osamu;Motegi Sei-Ichiro, European journal of dermatology : EJD, 30, 6

  DOI
• Inhibition of skin fibrosis in systemic sclerosis by botulinum toxin B via the suppression of oxidative stress., Baral Hritu;Sekiguchi Akiko;Uchiyama Akihiko;Nisaa Amalia Syahla;Yamazaki Sahori;Inoue Yuta;Yokoyama Yoko;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Akai Ryoko;Iwawaki Takao;Ishikawa Osamu;Motegi Sei-Ichiro, Apr. 2021, The Journal of dermatology, 48, 7

  DOI
• Antifibrotic effects and mechanisms of mesenchymal stem cell-derived exosomes in a systemic sclerosis mouse model: Possible contribution of miR-196b-5p., Baral Hritu;Uchiyama Akihiko;Yokoyama Yoko;Sekiguchi Akiko;Yamazaki Sahori;Amalia Syahla Nisaa;Inoue Yuta;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Matsuzaki Toshiyuki;Motegi Sei-Ichiro, Aug. 2021, Journal of dermatological science, 104, 1

  DOI
• Anti-polymyositis/Scl antibody-positive overlap syndrome of diffuse cutaneous systemic sclerosis, dermatomyositis, systemic lupus erythematosus, and antiphospholipid syndrome., Saito Shintaro;Endo Yukie;Nishio Mayu;Uchiyama Akihiko;Uehara Akihito;Toki Sayaka;Yasuda Masahito;Ishikawa Osamu;Muro Yoshinao;Motegi Sei-Ichiro, Nov. 2021, The Journal of dermatology, 49, 2

  DOI
• Tumor suppressive effect of anti-PD-1 antibody against angiosarcoma in a mouse model., Sekiguchi Akiko;Ishikawa Mai;Fujiwara Chisako;Inoue Yuta;Yamazaki Sahori;Uchiyama Akihiko;Motegi Sei-Ichiro, Nov. 2021, Journal of dermatological science, 105, 1

  DOI
• Spontaneous pneumomediastinum developed after steroid pulse therapy in diffuse cutaneous systemic sclerosis patient: A case report., Endo Yukie;Kim Jain;Uchiyama Akihiko;Yasuda Masahito;Hara Kenichiro;Motegi Sei-Ichiro, Jan. 2022, The Journal of dermatology, 49, 6

  DOI
• Real-world effectiveness and safety of baricitinib in Japanese patients with atopic dermatitis: A single-center retrospective study., Uchiyama Akihiko;Fujiwara Chisako;Inoue Yuta;Motegi Sei-Ichiro, Mar. 2022, The Journal of dermatology, 49, 4

  DOI
• Possible suppressive effects of baricitinib on serum IL-22 levels in atopic dermatitis., Uchiyama Akihiko;Fujiwara Chisako;Inoue Yuta;Ishikawa Mai;Motegi Sei-Ichiro, Apr. 2022, Journal of dermatological science, 106, 3

  DOI
• Possible suppressive effects of tranilast on NLRP3 inflammasome activation in necrobiosis lipoidica., Uchiyama Akihiko;Kosaka Keiji;Okada Katsuyuki;Motegi Sei-Ichiro, Jul. 2022, The Journal of dermatology, 49, 12

  DOI
• Capillaroscopy in Pigmented Basal Cell Carcinoma Smaller than 3-mm Diameter: A Report of Four Lesions., Saito Shintaro;Kuriyama Yuko;Uchiyama Akihiko;Yasuda Masahito;Motegi Sei-Ichiro, Aug. 2022, Acta dermato-venereologica, 102

  DOI
• Radiotherapy for Epstein-Barr Virus-Positive Mucocutaneous Ulcer at the Lower Leg Skin: A Case Report., Kubo Nobuteru;Okano Naoko;Kawamura Hidemasa;Uchiyama Akihiko;Ohno Tatsuya, Oct. 2022, Cureus, 14, 10

  DOI
• Real-world effectiveness and safety of bosentan in Japanese patients with systemic sclerosis: A single-center retrospective study., Ishikawa Mai;Endo Yukie;Yamazaki Sahori;Sekiguchi Akiko;Uchiyama Akihiko;Motegi Sei-Ichiro, Jan. 2023, The Journal of dermatology, 50, 6

  DOI
• Real-world effectiveness and safety of upadacitinib in Japanese patients with atopic dermatitis: a two-centre retrospective study., Kosaka Keiji;Uchiyama Akihiko;Ishikawa Mai;Watanabe Goichi;Motegi Sei-Ichiro, European journal of dermatology : EJD, 32, 6

  DOI
• Case report: further delineation of AEBP1-related Ehlers-Danlos Syndrome (classical-like EDS type 2) in an additional patient and comprehensive clinical and molecular review of the literature., Yamaguchi Tomomi;Hayashi Shujiro;Nagai So;Uchiyama Akihiko;Motegi Sei-Ichiro;Fujikawa Tomomi;Takiguchi Yuri;Kosho Tomoki, May 2023, Frontiers in genetics, 14

  DOI
• TRPV4 Regulates the Development of Psoriasis by Controlling Adenosine Triphosphate Expression in Keratinocytes and the Neuroimmune System., Amalia Syahla Nisaa;Baral Hritu;Fujiwara Chisako;Uchiyama Akihiko;Inoue Yuta;Yamazaki Sahori;Ishikawa Mai;Kosaka Keiji;Sekiguchi Akiko;Yokoyama Yoko;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Shibasaki Koji;Motegi Sei-Ichiro, May 2023, The Journal of investigative dermatology

  DOI
• Kaempferol therapy improved MC903 induced-atopic dermatitis in a mouse by suppressing TSLP, oxidative stress, and type 2 inflammation., Nasanbat Bolor;Uchiyama Akihiko;Amalia Syahla Nisaa;Inoue Yuta;Yokoyama Yoko;Ogino Sachiko;Torii Ryoko;Hosoi Mari;Motegi Sei-Ichiro, Jun. 2023, Journal of dermatological science, 111, 3

  DOI
• Keratinocyte-Specific SOX2 Overexpression Suppressed Pressure Ulcer Formation after Cutaneous Ischemia-Reperfusion Injury via Enhancement of Amphiregulin Production., Inoue Yuta;Uchiyama Akihiko;Amalia Syahla Nisaa;Ishikawa Mai;Kosaka Keiji;Sekiguchi Akiko;Ogino Sachiko;Yokoyama Yoko;Torii Ryoko;Hosoi Mari;Akai Ryoko;Iwawaki Takao;Morasso Maria I;Motegi Sei-Ichiro, Jul. 2023, The Journal of investigative dermatology

  DOI
• Transient receptor potential vanilloid 4 promotes cutaneous wound healing by regulating keratinocytes and fibroblasts migration and collagen production in fibroblasts in a mouse model., Taivanbat Bayarmaa;Yamazaki Sahori;Nasanbat Bolor;Uchiyama Akihiko;Amalia Syahla Nisaa;Nasan-Ochir Munkhjargal;Inoue Yuta;Ishikawa Mai;Kosaka Keiji;Sekiguchi Akiko;Ogino Sachiko;Yokoyama Yoko;Torii Ryoko;Hosoi Mari;Shibasaki Koji;Motegi Sei-Ichiro, Oct. 2023, Journal of dermatological science

  DOI
• An adult case of systemic mastocytosis, ;;;;, Nov. 2012, 66, 12, 969, 973

  DOI
• A case of mycosis fungoides with large cell transformation arising after the treatment of diffuse large B-cell lymphoma in the stomach, ;;;;, Nov. 2013, 67, 12, 997, 1001

  DOI
• Transient neonatal zinc deficiency(TNZD)の1例, ;;;, Apr. 2022, 132, 4, 665
• 腫瘍3mm未満の基底細胞癌におけるCapillaroscopy所見の検討, ;;;;;;;;, Sep. 2022, 26, 2, 49
• QOL向上を目指すHAE治療戦略とは　遺伝性血管性浮腫はNear Normal Lifeを目指す時代に, 内山 明彦, May 2023, 133, 5, 1311
• 抗SMN抗体陽性びまん皮膚硬化型全身性強皮症,多発性筋炎のオーバーラップ症候群の1例, ;;;;;;;, May 2023, 133, 5, 1357
• 当科外来患者における局所多汗症の実態と皮膚疾患との関連について, ;;;, Aug. 2023, 73, 3, 256
• Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway., Bajpai Deepti;Mehdizadeh Spencer;Uchiyama Akihiko;Inoue Yuta;Sawaya Andrew;Overmiller Andrew;Brooks Stephen R;Hasneen Kowser;Kellett Meghan;Palazzo Elisabetta;Motegi Sei-Ichiro;Yuspa Stuart H;Cataisson Christophe;Morasso Maria I, May 2021, Oncogene, 40, 21

  DOI
• A case of diabetes insipidus diagnosed from the development of acquired systemic anhidrosis, ;;;;;;;, Aug. 2013, 67, 9, 681, 684

  DOI
• Transient neonatal zinc deficiency(TNZD)の1例, ;;;, May 2022, 132, 5, 1303
• 眼部帯状疱疹後に対側の眼窩尖端症候群を来した53歳男性例, ;;;;;;, Mar. 2023, 63, 3, 180
• 褥瘡を予防できる新たな治療法を目指して　褥瘡モデルマウスを用いた検討, ;;;;;, Feb. 2018, 128, 2, 232
• 皮膚T細胞性リンパ腫とリンパ節原発B細胞性リンパ腫が併発した1例, ;;, Mar. 2018, 128, 3, 430
• 【薬疹】HLA-B*58:01保有者に生じたアロプリノールによるStevens-Johnson症候群の1例, ;;;;;;, Sep. 2023, 65, 10, 1467
• Case report of anti-survival motor neuron complex antibody-positive overlap syndrome of diffuse cutaneous systemic sclerosis and idiopathic inflammatory myopathies., Saito Masatsugu;Uchiyama Akihiko;Kim Jain;Endo Yukie;Yasuda Masahito;Aoki Sho;Ikeda Yoshio;Nishino Ichizo;Motegi Sei-Ichiro, Dec. 2023, The Journal of dermatology

  DOI
• Real-world effectiveness and safety of abrocitinib in 12 Japanese patients with atopic dermatitis and transcriptome analysis with peripheral blood., Uchiyama Akihiko;Kosaka Keiji;Ishikawa Mai;Inoue Yuta;Motegi Sei-Ichiro, Mar. 2024, The Journal of dermatology

  DOI
• 転写因子SOX2による皮膚虚血再灌流障害(急性期褥瘡)における制御機構の解明および新規治療法の開発, 内山 明彦, 2021, 29, 77, 80
• ステロイド投与中に縦隔気腫を合併した抗RNAポリメラーゼIII抗体陽性全身性強皮症の1例, ;;;;;, Nov. 2021, 51回, 200
• 毛細血管拡張を伴った剣創状強皮症に対する治療経験のまとめ, ;;;;;;;, Nov. 2021, 51回, 221
• 【薬疹】HLA-B*58:01保有者に生じたアロプリノールによるStevens-Johnson症候群の1例, ;;;;;;, Sep. 2023, 65, 10, 1467
• ボツリヌス毒素局所注入による褥瘡と炎症性皮膚疾患の制御機構, 内山 明彦, Sep. 2021, 7, 1, 27
• 多発性の皮下硬結を呈したループス血管炎の1例, ;;;;;;;;, Dec. 2023, 53回, 193
• 心タンポナーデを発症した抗U3-RNP抗体陽性の全身性強皮症の1例, ;;;;;;;;, Dec. 2023, 53回, 211
• 多発性の皮下硬結を呈したループス血管炎の1例, ;;;;;;;;, Dec. 2023, 53回, 219
• 群馬大学皮膚科における天疱瘡初期治療中の免疫グロブリン静注療法のまとめ, ;;;;;;;;;;;;;;, Jan. 2024, 134, 1, 83

MISC

• Beneficial Effect of Botulinum Toxin-a on Raynaud's Phenomenon in Japanese Patients with Systemic Sclerosis: A Prospective, Open-Label Trial, Sei-ichiro Motegi; Kazuya Yamada; Sayaka Toki; Akihiko Uchiyama; Tetsuya Nakamura; Osamu Ishikawa, Oct. 2015, ARTHRITIS & RHEUMATOLOGY, 67, Summary international conference
• THE REGULATION OF MESENCHYMAL STEM CELLS IN MELANOMA BY MFG-E8, Sei-Ichiro Motegi; Kazuya Yamada; Akihiko Uchiyama; Sachiko Ogino; Yoko Yokoyama; Yuko Takeuchi; Osamu Ishikawa, Oct. 2014, JOURNAL OF DERMATOLOGY, 41, 15, 15, Summary international conference
• 後天性全身性無汗症を契機に診断された中枢性尿崩症の1例, 内山 明彦; 田子 修; 茂木 精一郎; 服部 友保; 永井 弥生; 高橋 舞; 荒川 浩一; 石川 治, 2013, 67, 9, 681, 684

  DOI
• 胃原発 diffuse large B-cell lymphoma の治療後,大細胞転化を伴う菌状息肉症を生じた1例, 内山 明彦; 田子 修; 山田 和哉; 永井 弥生; 石川 治, 2013, 67, 12, 997, 1001

  DOI

Books etc

• 皮膚科カラ―アトラス 第3版, Contributor, Feb. 2017

Presentations

• Transcriptome analysis identified transcription factor SOX2 primes human oral mucosa for rapid wound healing, Uchiyama Akihiko, The 44th annual meeting of the Japanese Society for Investigative Dermatology, 08 Nov. 2019, English, International conference
• 創傷治癒における温故知新 ～なぜ口腔内のキズはすぐに治るのか？～, 内山 明彦, 香川県研究皮膚科フォーラム, 25 Jul. 2019, Japanese, Domestic conference
• 急性期褥瘡を解き明かす～新たな治療法を目指して～, 内山 明彦, 第6回群馬皮膚創傷治癒研究会, Jun. 2016, Japanese, Domestic conference
• Mesenchymal stem cells-derived MFG-E8 accelerates cutaneous wound healing in diabetic mice model., Uchiyama Akihiko, Annual meeting of society of Investigative dematology 2016, May 2016, English, International conference
• ボツリヌス毒素による皮膚虚血再還流障害に対する防御機構：褥瘡モデルマウスを用いた検討, 内山 明彦, 第62回北関東医学会, Sep. 2015, Japanese, Domestic conference
• Protective effect of botulinum toxin A after cutaneous ischemia-reperfusion injury, Uchiyama Akihiko, The annual meeting of ESDR 2015, Sep. 2015, English, International conference
• ボツリヌス毒素局所注入によって褥瘡を予防する～褥瘡モデルマウスを用いた検討～, 内山 明彦, 第114回日本研究皮膚科学会総会, May 2015, Japanese, Domestic conference
• ボツリヌス毒素による皮膚虚血再還流障害の制御：褥瘡モデルマウスを用いた検討, 内山 明彦, 分子皮膚科学フォーラム, Apr. 2015, Japanese, Domestic conference
• Protective effect of MFG-E8 after cutaneous ischemia-reperfusion injury, Uchiyama Akihiko, The 39th annual meeting of the Japanese Society for Investigative Dermatology, Dec. 2014, English, International conference
• 分泌蛋白質MFG-E8による皮膚創傷治癒の制御, 内山 明彦, 第61回北関東医学会, 25 Sep. 2014, Japanese, Domestic conference
• The role of MFG-E8 in cutaneous ischemia-reperfusion injury, Uchiyama Akihiko, Annual meeting of Society of Investigative dematology 2014, May 2014, English, International conference
• 創傷治癒におけるMFG-E8による血管新生の制御, 内山 明彦, 第60回北関東医学会総会, Sep. 2013, Japanese, Domestic conference
• The regulation of skin wound healing by MFG-E8, Uchiyama Akihiko, International Investigative Dermatology 2013, May 2013, English, International conference
• Role of MFG-E8 in skin wound healing, Uchiyama Akihiko, The 37th annual meeting of the Japanese Society for Investigative Dermatology, Dec. 2012, English, International conference

Awards

• Apr. 2020

  共同研究・競争的資金等の業績ID対象リソースIRI
• Jan. 2020
• Jan. 2020
• Nov. 2019
• May 2019
• The Fellows Award for Research Excellence (FARE) 2018 in NIH, Uchiyama Akihiko, National Institutes of Health, Sep. 2018
• Jan. 2018
• Dec. 2016
• Apr. 2016
• Dec. 2015
• Sep. 2015
• Apr. 2015
• Nov. 2014
• Sep. 2014
• May 2014
• Sep. 2013

Research Projects

• Nov. 2019, Principal investigator, Competitive research funding

  対象リソースIRI
• May 2019, Principal investigator, Competitive research funding
• Inherent features in human oral epithelia determine heightened wound healing, Uchiyama Akihiko, Jan. 2018, Mar. 2019, Principal investigator, Competitive research funding
• Apr. 2016, Sep. 2016, Principal investigator, Competitive research funding
• Uchiyama Akihiko, GSK Japan, GSK Japan Research Grant, May 2015, Sep. 2016, Principal investigator, Competitive research funding
• Protective Effect of MFG-E8 After Cutaneous Ischemia-reperfusion Injury, Uchiyama Akihiko, Apr. 2015, Mar. 2016, Principal investigator, Competitive research funding
• Apr. 2015, Mar. 2016, Principal investigator, Competitive research funding
• Sep. 2014, Mar. 2015, Principal investigator, Competitive research funding
• Apr. 2014, Mar. 2015, Principal investigator, Competitive research funding