Nanotechnology/Materials, Molecular biochemistry

Organic Chemistry

Bioorganic Chemistry

Nucleic Acid Chemistry

Natural Product Chemistry

Alternate stranded triplex formation of chimeric DNA composed of tandem a- and b-anomeric strands, Kazuo Shinozuka / Noritake Matsumoto / Hideo Suzuki / Tomohisa Moriguchi / Hiroaki Sawai, No, Nov. 2002, J. Chem. Soc. Chem. Comm.

Unique participation of unprotected internucleotidic phosphodiester residues on unexpected cleavage reaction of Si-O bond of the diisopropylsilandiyl group used as a linker for the solid-phase synthesis of 5' -terminal guanylated oligodeoxynucleotides, Masatoshi Ushioda / Michinori Kadokura / Tomohisa Moriguchi / Akio Kobori / Morihiro Aoyagi / Kohji Seio / Mitsuo Sekine, No, Sep. 2002, Helvetica Chimica Acta

Solid phase synthesis of a 5' -terminal TMG-capped trinucleotide block of U1 snRNA, Michinori Kadokura / Takeshi Wada / Kohji Seio / Tomohisa Moriguchi / Jochen Huber / Reinhard Luhrmann / Mitsuo Sekine, No, Nov. 2001, Tetrahedron Letters

Total synthesis of agrocin 84 and phosmidosine as naturally occurring nucleotidic antiboitics having P-N bond linkages, Mitsuo Sekine / Tomohisa Moriguchi / Takeshi Wada / Kohji Seio, No, Nov. 2001, 有機合成化学協会誌

Novel fluorescent oligo-DNA probe bearing a multi-conjugated nucleoside with a fluorophore and a non-fluorescent intercalator as a quencher, MORIGUCHI TOMOHISA / SHINOZUKA KAZUO / SAWAI HIROAKI, No, May 2006, Bioorganic and Medicial Chemistry Letters

Novel anthraquinone conjugate of 2,2-bis(hydroxymethyl)propionic acid incorporated to a TFO with phosphodiester linkage facilitates triplex formation with dsDNA bearing a pyrimidine-gapped polypurine sequence, MORIGUCHI TOMOHISA / SHINOZUKA KAZUO, No, Mar. 2004, Bioorganic and Medicinal Chemistry Letters

Synthesis of enol adenosine 5'-phosphate derivatives by the Perkow reaction of a silylated adenosine 5'-phosphonate derivative with a-halo ketones, MORIGUCHI TOMOHISA / 関根 光雄, Yes, Mar. 2004, Letters in Organic Chemistry

Novel dinucleoside phosphotriester unit conjugated with an intercalative moiety in a stereospecific manner enhances thermal stability of an alternate-stranded triple helix, MIYASITA MASANOR/MATSUMOTO NORITAKE/MORIGUCHI TOMOHISA/SHINOZUKA KAZUO, No, Nov. 2003, Tetrahedron Letters

Synthesis and duplex-forming property of oligonucleotides bearing a novel polyamine-modified intercalator at the terminal or the internal position, MORIGUCHI TOMOHISA / SHINOZUKA KAZUO, Yes, Apr. 2006, Nucleosides Nucleotides Nucleic Acids

Modified a-b chimeric oligoDNA bearing a multi-conjugate of 2,2-bis(hydroxymethyl)propionic acid-anthraquinone-polyamine exhibited improved and stereo-nonspecific triplex-forming ability, MORIGUCHI TOMOHISA / SHINOZUKA KAZUO, No, Feb. 2006, Chemical Communications

Crystallization and preliminary X-ray crystallographic analysis of yeast tyrosyl-tRNA synthetase complexed with its cognate tRNA, MORIGUCHI TOMOHISA / 関根 光雄 / 西川 一八, No, Apr. 2006, Protein and Peptide Letters

First synthesis and anti-cancer activity of phosmidosine and its related compounds, MORIGUCHI TOMOHISA / 関根 光雄, Yes, May 2002, Journal of Organic Chemistry

Synthesis and properties of oligodeoxynucleotides having an N-phosphoryl group, MORIGUCHI TOMOHISA / 関根 光雄, Yes, Jun. 2003, European Journal of Organic Chemistry

Synthesis and stability of 1-phenylethynyl phosphate derivatives and their phosphoryl transfer activity, MORIGUCHI TOMOHISA / 関根 光雄, Yes, Feb. 2004, Letters in Organic Chemistry

Formation and stability of alternate-stranded triplex formed with alpha, beta-chimeric oligoDNA, Yoshihiro Hirose, Aimi Kadoya, Noritake Matsumoto, Takanori Miyashita, Tomohisa Moriguchi, Kazuo Shinozuka, No, Nov. 2002, Nucleic Acids Research Supplement

α-β Chimeric oligo-DNA bearing intercalator-conjugated nucleobase inside the linker sequence remarkably improves the thermal stability of an alternate-stranded triple helix, MORIGUCHI TOMOHISA / SHINOZUKA KAZUO, No, Dec. 2004, Bioorganic and Medicinal Chemistry Letters

Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms, Masaru Tsunoda, Yoshio Kusakabe, Nobutada Tanaka, Satoshi Ohno, Masashi Nakamura, Toshiya Senda, Tomohisa Moriguchi, Norio Asai, Mitsuo Sekine, Takashi Yokogawa, Kazuya Nishikawa, and Kazuo T. Nakamura, No, Jul. 2007, Nucleic Acids Research

Development of DNA-intercalator-polyamine multi-conjugate bearing the ability of the sequence-specific RNA hydrolysis, Tomohisa Moriguchi, Tomoyuki Ohike, Kazuo Shinozuka, Yes, Nov. 2006, Nucleic Acids Symposium Series

Investigation of antisense DNA having C-5 polyamine substituted 2’-deoxyuridine derivative, Hideaki Sakai, Tomohisa Moriguchi, Hideo Suzuki, Makoto Matsukura, Kazuo Shinozuka, No, Nov. 2001, Nucleic Acids Research Supplement, 1

Synthesis of small multifunctional molecules having nucleic acid binding property, Kumiko Nakanuma, Tomohisa Moriguchi, Hideo Suzuki, Kazuo Shinozuka, No, Nov. 2001, Nucleic Acids Research Supplement

Spermine Moiety Attached to the C-5 Position of Deoxyuridine Enhances the Duplex Stability of the Phosphorothioate DNA/Complementary DNA and Shows the Susceptibility of the Substrate to RNase H, T. Moriguchi, H. Sakai, H. Suzuki, K. Shinozuka, Yes, Apr. 2008, Chem Pharm. Bull.

Synthesis and Properties of Oligonucleotides Containing Silylated Pyrene Derivatives, T. Moriguchi, M. Hattori, T. Sekiguchi, M. Ichimura, K. Shinozuka, Yes, Nov. 2008, Nucleid Acids Res. Symp. Ser.,

Cholesterol Analogs Labeled with Novel Silylated Fluorescent Compounds, Yes, Apr. 2009, Chem. Lett

Investigation of the mechanism of the fluorescent emmision of the silylated pyrene-modified DNA., T. Moriguchi, M. Hattori, M. Sekiguchi, K. Shinozuka, Yes, Nov. 2009, Nucleic Acids Res. Sym. Ser.

Synthesis and properties of novel oligodeoxynucleotides containing 6,3'-methanodeoxyuridine, Tomohisa Moriguchi, Fumisada Yamato, Kazuo Shinozuka, Yes, May 2008, Chemistry Letters

Synthesis and Properties of Fluorescent Biological Molecules Labeled with Novel Silylated Perylene Derivative, , Y. Sato, A. Ozaki, M. Hosaka, T. Moriguchi, K. Shinozuka,, No, 2011, Key Engineering Materials,

Modified OligoDNA having Two Consecutive Silylated-pyrene Moieties in Minor Groove Exhibiting an Excimer Fluorescent Signal upon Binding to Fully-complementary DNA Strand,, M. Mogi, M.D. Gias Uddine, M. Ichimura, T. Moriguchi, K. Shinozuka, , No, Nov. 2010, Chem. Lett.,

Cholesterol Biosynthesis Pathway Intermediates and Inhibitors Regulate Glucose-stimulated Insulin Secretion and Secretory Granule Formation in Pancreatic β-Cells, , M. Tsuchiya, M. Hosaka, T. Moriguchi, S. Zhang, M. Suda, H. Yokota-Hashimoto, K. Shinozuka, T. Takeuchi, , No, Oct. 2010, Endoclinology,

Stabilizing Effectof Propionic Acid Derivative of Anthraquinone-Polyamine Conjugate Incorporated into Chimeric Oligonucleotides on the Alternate-Stranded Triple Helix, T. Moriguchi, A.T.M. Zafrul Azam, K. Shinozuka, Yes, Jun. 2011, Bioconjugate Chemistry

Pseudo-Dumbbell-Type Molecular Beacon Probes Bearing Modified Deoxyuridine Derivatives and a Silylated Pyrene as a Fluorophore, Chowdhury, Jakir Ahmed; Moriguchi, Tomohisa; Shinozuka, Kazuo, No, 2015, BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Synthesis and Properties of Novel Fluorescently Labeled Oligonucleotides Possessing Silylated Pyrene at the 5 '-Terminus, Moriguchi, Tomohisa; Moki, Daisuke; Sekiguchi, Tohru; Kato, Takahiko; Shinozuka, Kazuo, Yes, 2015, CHEMISTRY LETTERS

Synthesis and Spectroscopic Properties of a Novel Bifunctional Pyrene Derivative and its Incorporation into OligoDNA, Moriguchi, Tomohisa; Hida, Satomi; Yoneda, Fumio; Shinozuka, Kazuo, Yes, 2015, AUSTRALIAN JOURNAL OF CHEMISTRY

Development of a Novel Stem-loop-type Molecular Beacon Probe Possessing Polyamine-connected Deoxyuridine and Silylated Pyrene, Chowdhury, Jakir Ahmed; Moriguchi, Tomohisa; Shinozuka, Kazuo, No, Dec. 2014, CHEMISTRY LETTERS

Development of the excimer probe responsible for DNA target bearing the silylated pyrenes at base moiety, Moriguchi, Tomohisa; Ichimura, Mayumi; Kato, Mitsuhisa; Suzuki, Kenya; Takahashi, Yuki; Shinozuka, Kazuo, Yes, 2014, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel method of the synthesis and hybridization properties of an oligonucleotide containing non-ionic diisopropylsilyl internucleotide linkage, Moriguchi, Tomohisa; Sekine, Mitsuaki; Shinozuka, Kazuo, Yes, Dec. 2013, BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and properties of molecular beacon DNA probe bearing novel silylated pyrene derivative, Md. Gias Uddin, T. Moriguchi, M. Ichimura, K. Shinozuka, No, Jun. 2012, Key Engineering Materials

Termini-free molecular beacon utilizing silylated perylene and anthraquinone attached to the C-5 position of pyrimidine nucleobase, Y. Sato, T. Moriguchi, K. Shinozuka, No, Jun. 2012, Chem. Lett.,

Investigation of the mechanism of the fluorescent emission of the silylated pyrene modified DNA, Tomohisa Moriguchi, Masayoshi Hattori, Tohru Sekiguchi, Kazuo Shinozuka, Yes, Nov. 2009, Nucleic Acids Symp. Ser

Spermine moiety attached to the C-5 position of deoxyuridine enhances the duplex stability of the phosphorothioate DNA/complementary DNA and shows the susceptibility of the substrate to RNase H, Tomohisa Moriguchi; Hideaki Sakai; Hideo Suzuki; Kazuo Shinozuka, Sep. 2008, CHEMICAL & PHARMACEUTICAL BULLETIN, 56, 9, 1259, 1263

Spermine moiety attached to the C-5 position of deoxyuridine enhances the duplex stability of the phosphorothioate DNA/complementary DNA and shows the susceptibility of the substrate to RNase H, Tomohisa Moriguchi; Hideaki Sakai; Hideo Suzuki; Kazuo Shinozuka, Sep. 2008, CHEMICAL & PHARMACEUTICAL BULLETIN, 56, 9, 1259, 1263

Synthesis and properties of novel oligodeoxynucleotides containing 6,3 '-methanodeoxyuridine, Tomohisa Moriguchi; Fumisada Yaniato; Kazuo Shinozuka, May 2008, CHEMISTRY LETTERS, 37, 5, 548, 549

Solid-phase synthesis of a 5 '-terminal TMG-capped trinucleotide block of U1 snRNA, M Kadokura; T Wada; K Seio; T Moriguchi; J Huber; R Luhrmann; M Sekine, Dec. 2001, TETRAHEDRON LETTERS, 42, 50, 8853, 8856

Solid-phase synthesis of a 5 '-terminal TMG-capped trinucleotide block of U1 snRNA, M Kadokura; T Wada; K Seio; T Moriguchi; J Huber; R Luhrmann; M Sekine, Dec. 2001, TETRAHEDRON LETTERS, 42, 50, 8853, 8856

Synthesis and Properties of Novel Fluorescently Labeled Oligonucleotides Possessing Silylated Pyrene at the 5 '-Terminus, Tomohisa Moriguchi; Daisuke Moki; Tohru Sekiguchi; Takahiko Kato; Kazuo Shinozuka, Jan. 2015, CHEMISTRY LETTERS, 44, 1, 44, 46

Synthesis and Properties of Novel Fluorescently Labeled Oligonucleotides Possessing Silylated Pyrene at the 5 '-Terminus, Tomohisa Moriguchi; Daisuke Moki; Tohru Sekiguchi; Takahiko Kato; Kazuo Shinozuka, Jan. 2015, CHEMISTRY LETTERS, 44, 1, 44, 46

Pseudo-Dumbbell-Type Molecular Beacon Probes Bearing Modified Deoxyuridine Derivatives and a Silylated Pyrene as a Fluorophore, Jakir Ahmed Chowdhury; Tomohisa Moriguchi; Kazuo Shinozuka, Mar. 2015, BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 88, 3, 496, 502

Synthesis and Spectroscopic Properties of a Novel Bifunctional Pyrene Derivative and its Incorporation into OligoDNA, Tomohisa Moriguchi; Satomi Hida; Fumio Yoneda; Kazuo Shinozuka, 2015, AUSTRALIAN JOURNAL OF CHEMISTRY, 68, 2, 256, 259

Synthesis and Spectroscopic Properties of a Novel Bifunctional Pyrene Derivative and its Incorporation into OligoDNA, Tomohisa Moriguchi; Satomi Hida; Fumio Yoneda; Kazuo Shinozuka, 2015, AUSTRALIAN JOURNAL OF CHEMISTRY, 68, 2, 256, 259

Cholesterol Analogs Labeled with Novel Silylated Fluorescent Compounds, Tomohisa Moriguchi; Masahiro Hosaka; Akihito Yoshinari; Akiko Ozaki; Toshiyuki Takeuchi; Kazuo Shinozuka, Oct. 2009, CHEMISTRY LETTERS, 38, 10, 966, 967

Cholesterol Analogs Labeled with Novel Silylated Fluorescent Compounds, Tomohisa Moriguchi; Masahiro Hosaka; Akihito Yoshinari; Akiko Ozaki; Toshiyuki Takeuchi; Kazuo Shinozuka, Oct. 2009, CHEMISTRY LETTERS, 38, 10, 966, 967

Novel method of the synthesis and hybridization properties of an oligonucleotide containing non-ionic diisopropylsilyl internucleotide linkage, Tomohisa Moriguchi; Mitsuaki Sekine; Kazuo Shinozuka, Dec. 2013, BIOORGANIC & MEDICINAL CHEMISTRY, 21, 24, 8013, 8018

Cholesterol Biosynthesis Pathway Intermediates and Inhibitors Regulate Glucose-Stimulated Insulin Secretion and Secretory Granule Formation in Pancreatic beta-Cells, Miho Tsuchiya; Masahiro Hosaka; Tomohisa Moriguchi; Shaojuan Zhang; Masayuki Suda; Hiromi Yokota-Hashimoto; Kazuo Shinozuka; Toshiyuki Takeuchi, Oct. 2010, ENDOCRINOLOGY, 151, 10, 4705, 4716

Cholesterol Biosynthesis Pathway Intermediates and Inhibitors Regulate Glucose-Stimulated Insulin Secretion and Secretory Granule Formation in Pancreatic beta-Cells, Miho Tsuchiya; Masahiro Hosaka; Tomohisa Moriguchi; Shaojuan Zhang; Masayuki Suda; Hiromi Yokota-Hashimoto; Kazuo Shinozuka; Toshiyuki Takeuchi, Oct. 2010, ENDOCRINOLOGY, 151, 10, 4705, 4716

Modified OligoDNA Having Two Consecutive Silylated-pyrene Moieties in Minor Groove Exhibiting an Excimer Fluorescent Signal upon Binding to Fully Complementary DNA Strand, Mika Mogi; Md Gias Uddin; Mayumi Ichimura; Tomohisa Moriguchi; Kazuo Shinozuka, Dec. 2010, CHEMISTRY LETTERS, 39, 12, 1254, 1255

Modified OligoDNA Having Two Consecutive Silylated-pyrene Moieties in Minor Groove Exhibiting an Excimer Fluorescent Signal upon Binding to Fully Complementary DNA Strand, Mika Mogi; Md Gias Uddin; Mayumi Ichimura; Tomohisa Moriguchi; Kazuo Shinozuka, Dec. 2010, CHEMISTRY LETTERS, 39, 12, 1254, 1255

Novel fluorescent oligoDNA probe bearing a multi-conjugated nucleoside with a fluorophore and a non-fluorescent intercalator as a quencher, S Kodama; S Asano; T Moriguchi; H Sawai; K Shinozuka, May 2006, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16, 10, 2685, 2688

Novel fluorescent oligoDNA probe bearing a multi-conjugated nucleoside with a fluorophore and a non-fluorescent intercalator as a quencher, S Kodama; S Asano; T Moriguchi; H Sawai; K Shinozuka, May 2006, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16, 10, 2685, 2688

Crystallization and preliminary X-ray crystallographic analysis of yeast tyrosyl-tRNA synthetase complexed with its cognate tRNA, Y Kusakabe; S Ohno; N Tanaka; M Nakamura; M Tsunoda; T Moriguchi; N Asai; M Sekine; T Yokogawa; K Nishikawa; KT Nakamura, 2006, PROTEIN AND PEPTIDE LETTERS, 13, 4, 417, 419

Crystallization and preliminary X-ray crystallographic analysis of yeast tyrosyl-tRNA synthetase complexed with its cognate tRNA, Y Kusakabe; S Ohno; N Tanaka; M Nakamura; M Tsunoda; T Moriguchi; N Asai; M Sekine; T Yokogawa; K Nishikawa; KT Nakamura, 2006, PROTEIN AND PEPTIDE LETTERS, 13, 4, 417, 419

Synthesis and duplex-forming property of oligonucleotides bearing a novel polyamine-modified intercalator at the terminal or the internal position, Tomohisa Moriguchi; Hirokazu Sekiguchi; Makoto Tachibana; Kazuo Shinozuka, 2006, NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 25, 4-6, 601, 612

Synthesis and duplex-forming property of oligonucleotides bearing a novel polyamine-modified intercalator at the terminal or the internal position, Tomohisa Moriguchi; Hirokazu Sekiguchi; Makoto Tachibana; Kazuo Shinozuka, 2006, NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 25, 4-6, 601, 612

Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms, Masaru Tsunoda; Yoshio Kusakabe; Nobutada Tanaka; Satoshi Ohno; Masashi Nakamura; Toshiya Senda; Tomohisa Moriguchi; Norio Asai; Mitsuo Sekine; Takashi Yokogawa; Kazuya Nishikawa; Kazuo T. Nakamura, 2007, NUCLEIC ACIDS RESEARCH, 35, 13, 4289, 4300

Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms, Masaru Tsunoda; Yoshio Kusakabe; Nobutada Tanaka; Satoshi Ohno; Masashi Nakamura; Toshiya Senda; Tomohisa Moriguchi; Norio Asai; Mitsuo Sekine; Takashi Yokogawa; Kazuya Nishikawa; Kazuo T. Nakamura, 2007, NUCLEIC ACIDS RESEARCH, 35, 13, 4289, 4300

Synthesis and Properties of Molecular Beacon DNA Probe Bearing Novel Silylated Pyrene Derivative, Md Gias Uddin; Tomohisa Moriguchi; Mayumi Ichimura; Kazuo Shinozuka, 2012, SILICON SCIENCE AND ADVANCED MICRO-DEVICE ENGINEERING II, 497, 47, +

Synthesis and Properties of Molecular Beacon DNA Probe Bearing Novel Silylated Pyrene Derivative, Md Gias Uddin; Tomohisa Moriguchi; Mayumi Ichimura; Kazuo Shinozuka, 2012, SILICON SCIENCE AND ADVANCED MICRO-DEVICE ENGINEERING II, 497, 47, +

Termini-free Molecular Beacon Utilizing Silylated Perylene and Anthraquinone Attached to the C-5 Position of Pyrimidine Nucleobase, Yuzuru Sato; Tomohisa Moriguchi; Kazuo Shinozuka, Apr. 2012, CHEMISTRY LETTERS, 41, 4, 420, 422

Unique participation of unprotected internucleotidic phosphodiester residues on unexpected cleavage reaction of the Si-O bond of the diisopropylsilandiyl group used as a linker for the solid-phase synthesis of 5 '-terminal guanylated oligodeoxynucleotides, M Ushioda; M Kadokura; T Moriguchi; A Kobori; M Aoyagi; K Seio; M Sekine, 2002, HELVETICA CHIMICA ACTA, 85, 9, 2930, 2945

Unique participation of unprotected internucleotidic phosphodiester residues on unexpected cleavage reaction of the Si-O bond of the diisopropylsilandiyl group used as a linker for the solid-phase synthesis of 5 '-terminal guanylated oligodeoxynucleotides, M Ushioda; M Kadokura; T Moriguchi; A Kobori; M Aoyagi; K Seio; M Sekine, 2002, HELVETICA CHIMICA ACTA, 85, 9, 2930, 2945

First synthesis and anticancer activity of phosmidosine and its related compounds, T Moriguchi; N Asai; K Okada; K Seio; T Sasaki; M Sekine, May 2002, JOURNAL OF ORGANIC CHEMISTRY, 67, 10, 3290, 3300

First synthesis and anticancer activity of phosmidosine and its related compounds, T Moriguchi; N Asai; K Okada; K Seio; T Sasaki; M Sekine, May 2002, JOURNAL OF ORGANIC CHEMISTRY, 67, 10, 3290, 3300

Novel dinucleoside phosphotriester unit conjugated with an intercalative moiety in a stereospecific manner enhances thermal stability of an alternate-stranded triple helix, T Miyashita; N Matsumoto; T Moriguchi; K Shinozuka, Sep. 2003, TETRAHEDRON LETTERS, 44, 40, 7399, 7402

Novel dinucleoside phosphotriester unit conjugated with an intercalative moiety in a stereospecific manner enhances thermal stability of an alternate-stranded triple helix, T Miyashita; N Matsumoto; T Moriguchi; K Shinozuka, Sep. 2003, TETRAHEDRON LETTERS, 44, 40, 7399, 7402

alpha-beta Chimeric oligo-DNA bearing intercalator-conjugated nucleobase inside the linker sequence remarkably improves thermal stability of an alternate-stranded triple helix, ATMZ Azam; M Hasegawa; T Moriguchi; K Shinozuka, Dec. 2004, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 14, 23, 5747, 5750

alpha-beta Chimeric oligo-DNA bearing intercalator-conjugated nucleobase inside the linker sequence remarkably improves thermal stability of an alternate-stranded triple helix, ATMZ Azam; M Hasegawa; T Moriguchi; K Shinozuka, Dec. 2004, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 14, 23, 5747, 5750

Novel anthraquinone conjugate of 2,2-bis(hydroxymethyl)propionic acid incorporated to a TFO with phosphodiester linkage facilitates triplex formation with dsDNA bearing a pyrimidine-gapped polypurine sequence, M Sato; T Moriguchi; K Shinozuka, Mar. 2004, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 14, 5, 1305, 1308

Novel anthraquinone conjugate of 2,2-bis(hydroxymethyl)propionic acid incorporated to a TFO with phosphodiester linkage facilitates triplex formation with dsDNA bearing a pyrimidine-gapped polypurine sequence, M Sato; T Moriguchi; K Shinozuka, Mar. 2004, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 14, 5, 1305, 1308

Synthesis and stability of 1-phenylethenyl phosphate derivatives and their phosphoryl transfer activity, T Moriguchi; K Okada; K Seio; M Sekine, Apr. 2004, LETTERS IN ORGANIC CHEMISTRY, 1, 2, 140, 144

Synthesis and stability of 1-phenylethenyl phosphate derivatives and their phosphoryl transfer activity, T Moriguchi; K Okada; K Seio; M Sekine, Apr. 2004, LETTERS IN ORGANIC CHEMISTRY, 1, 2, 140, 144

Synthesis of enol adenosine 5 '-phosphate derivatives by the Perkow reaction of a silylated adenosine 5 '-phosphonate derivative with alpha-halo ketones, T Moriguchi; K Okada; K Seio; M Sekine, Jul. 2004, LETTERS IN ORGANIC CHEMISTRY, 1, 3, 246, 248

Synthesis of enol adenosine 5 '-phosphate derivatives by the Perkow reaction of a silylated adenosine 5 '-phosphonate derivative with alpha-halo ketones, T Moriguchi; K Okada; K Seio; M Sekine, Jul. 2004, LETTERS IN ORGANIC CHEMISTRY, 1, 3, 246, 248

Stabilizing Effect of Propionic Acid Derivative of Anthraquinone-Polyamine Conjugate Incorporated into alpha-beta Chimeric Oligonucleotides on the Alternate-Stranded Triple Helix, Tomohisa Moriguchi; A. T. M. Zafrul Azam; Kazuo Shinozuka, Jun. 2011, BIOCONJUGATE CHEMISTRY, 22, 6, 1039, 1045

Synthesis and Properties of Fluorescent Biological Molecules Labeled with Novel Silylated Perylene Derivative, Yuzuru Sato; Akiko Ozaki; Masahiro Hosaka; Tomohisa Moriguchi; Kazuo Shinozuka, 2011, SILICON SCIENCE AND ADVANCED MICRO-DEVICE ENGINEERING I, 459, 63, +

Synthesis and Properties of Fluorescent Biological Molecules Labeled with Novel Silylated Perylene Derivative, Yuzuru Sato; Akiko Ozaki; Masahiro Hosaka; Tomohisa Moriguchi; Kazuo Shinozuka, 2011, SILICON SCIENCE AND ADVANCED MICRO-DEVICE ENGINEERING I, 459, 63, +

Development of a Novel Stem-loop-type Molecular Beacon Probe Possessing Polyamine-connected Deoxyuridine and Silylated Pyrene, Jakir Ahmed Chowdhury; Tomohisa Moriguchi; Kazuo Shinozuka, Dec. 2014, CHEMISTRY LETTERS, 43, 12, 1915, 1917

Development of the excimer probe responsible for DNA target bearing the silylated pyrenes at base moiety, Tomohisa Moriguchi; Mayumi Ichimura; Mitsuhisa Kato; Kenya Suzuki; Yuki Takahashi; Kazuo Shinozuka, Sep. 2014, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 24, 18, 4372, 4375

Development of the excimer probe responsible for DNA target bearing the silylated pyrenes at base moiety, Tomohisa Moriguchi; Mayumi Ichimura; Mitsuhisa Kato; Kenya Suzuki; Yuki Takahashi; Kazuo Shinozuka, Sep. 2014, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 24, 18, 4372, 4375

2002, 2712-13

Total synthesis of agrocin 84 and phosmidosine as naturally occurring nucleotidic antibiotics having P-N bond linkages, Mitsuo Sekine; Tomohisa Moriguchi; Takeshi Wada; Kohji Seio, 2001, Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 59, 11, 1109, 1120, Book review

2006, pp 335-337

2003, pp. 2260-67

2001, 1, 69, 70

2002, 2, 263, 264

2006, 50, 187, 188

2001, 1

2009, 53, 31, 32

2008, 52, 255, 256

2011

2009, 53, 31-32.

2013, 21, 24, 8013, 8018

Pseudo-dumbbell-type molecular beacon probes bearing modified deoxyuridine derivatives and a silylated pyrene as a fluorophore, Jakir Ahmed Chowdhury; Tomohisa Moriguchi; Kazuo Shinozuka, 2015, Bulletin of the Chemical Society of Japan, 88, 3, 496, 502

Development of a novel stem-loop-type molecular beacon probe possessing polyamine-connected deoxyuridine and silylated pyrene, Jakir Ahmed Chowdhury; Tomohisa Moriguchi; Kazuo Shinozuka, 2014, Chemistry Letters, 43, 12, 1915, 1917

Alternate stranded triplex formation of chimeric DNA composed of tandem a- and b-anomeric strands, Kazuo Shinozuka; Noritake Matsumoto; Hideo Suzuki; Tomohisa Moriguchi; Hiroaki Sawai, 2002, J. Chem. Soc. Chem. Comm., 2712-13

Total synthesis of agrocin 84 and phosmidosine as naturally occurring nucleotidic antibiotics having P-N bond linkages, Mitsuo Sekine; Tomohisa Moriguchi; Takeshi Wada; Kohji Seio, 2001, Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 59, 11, 1109, 1120, Book review

Modified a-b chimeric oligoDNA bearing a multi-conjugate of 2,2-bis(hydroxymethyl)propionic acid-anthraquinone-polyamine exhibited improved and stereo-nonspecific triplex-forming ability, MORIGUCHI TOMOHISA; SHINOZUKA KAZUO, 2006, Chemical Communications, pp 335-337

Synthesis and properties of oligodeoxynucleotides having an N-phosphoryl group, MORIGUCHI TOMOHISA; 関根 光雄, 2003, European Journal of Organic Chemistry, pp. 2260-67

Synthesis of small multifunctional molecules having nucleic acid binding property, Kumiko Nakanuma; Tomohisa Moriguchi; Hideo Suzuki; Kazuo Shinozuka, 2001, Nucleic Acids Research Supplement, 1, 69, 70

Formation and stability of alternate-stranded triplex formed with alpha, beta-chimeric oligoDNA, Yoshihiro Hirose; Aimi Kadoya; Noritake Matsumoto; Takanori Miyashita; Tomohisa Moriguchi; Kazuo Shinozuka, 2002, Nucleic Acids Research Supplement, 2, 263, 264

Development of DNA-intercalator-polyamine multi-conjugate bearing the ability of the sequence-specific RNA hydrolysis, Tomohisa Moriguchi; Tomoyuki Ohike; Kazuo Shinozuka, 2006, Nucleic Acids Symposium Series, 50, 187, 188

Investigation of antisense DNA having C-5 polyamine substituted 2’-deoxyuridine derivative, Hideaki Sakai; Tomohisa Moriguchi; Hideo Suzuki; Makoto Matsukura; Kazuo Shinozuka, 2001, Nucleic Acids Research Supplement, 127, 128

Investigation of the mechanism of the fluorescent emmision of the silylated pyrene-modified DNA., T. Moriguchi; M. Hattori; M. Sekiguchi; K. Shinozuka, 2009, Nucleic Acids Res. Sym. Ser., 53, 31, 32

Synthesis and Properties of Oligonucleotides Containing Silylated Pyrene Derivatives, T. Moriguchi; M. Hattori; T. Sekiguchi; M. Ichimura; K. Shinozuka, 2008, Nucleid Acids Res. Symp. Ser.,, 52, 255, 256

Synthesis and properties of novel oligodeoxynucleotides containing 6,3′-methanodeoxyuridine, Tomohisa Moriguchi; Fumisada Yamato; Kazuo Shinozuka, 05 May 2008, Chemistry Letters, 37, 5, 548, 549

Termini-free molecular beacon utilizing silylated perylene and anthraquinone attached to the C-5 position of pyrimidine nucleobase, Yuzuru Sato; Tomohisa Moriguchi; Kazuo Shinozuka, 2012, Chemistry Letters, 41, 4, 420, 422

Investigation of the mechanism of the fluorescent emission of the silylated pyrene modified DNA, Tomohisa Moriguchi; Masayoshi Hattori; Tohru Sekiguchi; Kazuo Shinozuka, 2009, Nucleic Acids Symp. Ser, 53, 31-32.

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Synthesis and triplex forming ability of Novel α-β chimeric oligonucleotides having an intercalator moiety at the linker portion, Pacfichem2005, 2005

Synthesis and alternate-stranded triplex forming ability of novel alpha-beta chimeric oligonucleotides bearing an intercalator-conjugated nucleobase, 第31回核酸化学シンポジウム, 2004

Synthesis and alternated-stranded triplex forming ability of novel α-β chimeric oligoDNA bearing an anthraquinone conjugate with 2.2-bis(hydroxymethyl)propionic acid, 日本化学会第85春季年会, 2005

Synthesis and sequense specific alternate-stranded triplex forming ability of novel lapha-beta chimeric oligoDNA bearing a muti-conjugate of 2.2'-bis(hydroxymethyl)propionic acid-anthraquinone-polyamine, 第15回アンチセンスシンポジウム, 2005

Synthesis of novel TFOs bearing an abasic portion and their triplex forming ability with a DNA duplex containing a pyrimidine-gapped polypurine strand, 3rd Internationla Symposium on Nucleic Acids Chemistry, 2003

Development of DNA-intercalator-polyamine multi-conjugate bearing the ability of the sequence-specific RNA hydrolysis, 2006

Preparation of Silylpyrene Derivatives and Their Application as Fluorescent Labeling Agent for Biological Molecules, 2006

Sequence Selective Recognition of Silylated Perylene-Labeled Molecular Beacon Probes, 2012

Fluorescent Properties of the Dumbbell-formed Silylated Pyrene ModifiedOligonucleotides, 2011