Life sciences, Radiology, particle beam therapy physics

Energy, Quantum beam science, particle beam therapy physics

Medical Physics

Particle Beam Therapy Physics

Fast generation of 511 keV gamma volumetric phase space using a conditional diffusion model in carbon ion radiotherapy, Caixun Zhang; Ken Yusa; Mutsumi Tashiro, No, Yes, Yes, Jun. 2026, Journal of Radiation Research and Applied Sciences, 19, 3, 102507, Scientific journal

For ultra-high dose rate carbon-ion irradiation, comparable beam parameters induce the equivalent cell sparing (FLASH) effect, Tsubouchi K, Yoshida Y, Yagi M, Minami K, Suda H, Nakao M, Yusa K, Tashiro M, Shimizu S, Ohno T, Ogawa K, No, No, No, Jun. 2026, Journal of Radiation Research, 67, 4, 487, 497, Scientific journal

A delta-based multi-omics model to predict adaptive radiotherapy benefit in patients with non-small cell lung cancer during carbon-ion radiotherapy, Zhuojun Ju, Nobuteru Kubo, Xiangdi Meng, Makoto Sakai, Mutsumi Tashiro, Tatsuya Ohno, No, No, No, May 2026, Physics in Medicine & Biology, 71, 095017, Scientific journal

Estimation of Tumor Control Probability of Carbon Ion Radiotherapy Using Cancer Type-specific Sensitivity Data, EUNHYE YU; TAKAHIRO OIKE; MAKOTO SAKAI; MUTSUMI TASHIRO; TATSUYA OHNO, No, No, No, Dec. 2025, Anticancer Research, 46, 1, 113, 122

Carbon ion FLASH irradiation reduces acute skin toxicity compared with conventional dose rate irradiation, Yukari Yoshida; Hiromu Suda; Mutsumi Tashiro; Ken Yusa; Masao Nakao; Koichi Ando; Akihisa Takahashi; Tatsuya Ohno, No, No, No, Dec. 2025, Scientific Reports, 16, 2307, Scientific journal

Assessment of upright immobilization methods for abdominal and head-and-neck cancer treatments in a carbon ion radiotherapy setting, Maria Varnava; Motohiro Kawashima; Akihiko Matsumura; Yoshiaki Oohashi; Makoto Miyazawa; Junichi Koya; Naoto Yamaguchi; Tomoaki Ogano; Mutsumi Tashiro; Tatsuya Ohno, No, No, No, Nov. 2025, Technical Innovations & Patient Support in Radiation Oncology, 36, 100356, Scientific journal

Partial abdominal carbon-ion FLASH irradiation spares lethality compared to conventional irradiation: impact of LET and dose rate, Wenteng Cao, Yukari Yoshida, Hiromu Suda, Shunsuke Inagaki, Naoto Urabe, Masao Nakao, Ken Yusa, Xiangdi Meng, Mutsumi Tashiro, Akihisa Takahashi, Tatsuya Ohno, No, No, No, Nov. 2025, Radiation Oncology, 20, 186, Scientific journal

Improving range estimation for carbon ion radiotherapy using artificial neural networks with Si/CdTe Compton camera, Caixun Zhang, Makoto Sakai, Ken Yusa, Xiangdi Meng, Mutsumi Tashiro, No, Yes, No, Oct. 2025, Physica Medica, 139, 105193, Scientific journal

A Dosimetric Evaluation of the Feasibility and Robustness of Ultra-hypofractionated Carbon Ion Radiotherapy Planning for the Treatment of Prostate Cancer, Hikaru Yumisaki, Nobuteru Kubo, Takahiro Oike, Hidemasa Kawamura, Mutsumi Tashiro, Masahiro Onishi, Tatsuya Ohno, No, No, No, Oct. 2025, Anticancer Research, 45, 10, 4453, 4464, Scientific journal

Low Dose-Averaged Linear Energy Transfer Contributes to Local Recurrence of Pancreatic Cancer Treated With Carbon Ion Radiation Therapy, Soichiro Sakamoto, Takahiro Oike, Daijiro Kobayashi, Yuhei Miyasaka, Makoto Sakai, Masahiko Okamoto, Shintaro Shiba, Kento Tomizawa, Narisa Dewi Maulany Darwis, Hanae Yoshida, Mutsumi Tashiro, Tatsuya Ohno, No, No, No, Jul. 2025, International Journal of Radiation Oncology - Biology - Physics, 123, 4, 1071, 1079, Scientific journal

Dose-Volume Constraints for Thoracic, Abdominal, and Pelvic Carbon Ion Radiotherapy: A Literature Review, Maria Varnava, Mutsumi Tashiro, Masahiko Okamoto, Ken Ando, Nobutero Kubo, Hidemasa Kawamura, Masahiro Onishi, Kei Shibuya, Takuya Kumazawa, Takeru Ohtaka, Tatsuya Ohno, No, No, No, 28 Mar. 2025, Cancer Medicine, 14, 7, e70840, Scientific journal

Evaluation of dose distributions and respiratory motion tolerance for layer-stacking conformal carbon-ion radiotherapy, Yuki Hasebe, Mutsumi Tashiro, Hiroshi Sakurai, No, No, Yes, 14 Nov. 2024, Radiological Physics and Technology, Scientific journal

Evaluation of monthly variations in electrometer calibration coefficients using a charge generator for radiation therapy, Motohiro Kawashima, Maria Varnava, Shuichi Ozawa, Hiromitsu Higuchi, Yoshihiko Hoshino, Mutsumi Tashiro, No, Yes, No, 01 Aug. 2024, Radiological Physics and Technology, 17, 770, 775, Scientific journal

Experimental study on Compton camera for boron neutron capture therapy applications, Sakai M, Tamaki S, Murata I, Parajuli RK, Matsumura A, Kubo N, Tashiro M, No, Yes, No, 18 Dec. 2023, Scientific Reports, 13, 1, 22883, Scientific journal

Dose distribution estimation toward CT-less adaptive carbon ion radiotherapy for liver tumors using the divided-volume matching technique., Chen Jing-Ni;Ohno Tatsuya;Tashiro Mutsumi, No, Yes, Yes, Oct. 2023, Physics in medicine and biology, 68, 20, 205018, Scientific journal

Improved Algorithm for Estimation of Linear Energy Transfer in Carbon Ion Radiotherapy Plans, Anakura, Mai;Kubota, Yoshiki;Oike, Takahiro;Matsumura, Akihiko;Sakai, Makoto;Kanematsu, Nobuyuki;Tashiro, Mutsumi;Ohno, Tatsuya, No, No, No, 23 Jun. 2023, ANTICANCER RESEARCH, 43, 7, 2975, 2984, Scientific journal

Assessment of a self‐inspection method and reporting measured electrometer correction factors for reference‐class electrometers in radiotherapy, Motohiro Kawashima; Maria Varnava; Shuichi Ozawa; Hiroki Okada; Hiromitsu Higuchi; Yoshihiko Hoshino; Mutsumi Tashiro, No, Yes, No, Jun. 2023, Journal of Applied Clinical Medical Physics, e14082, Scientific journal

Dose–volume constraints for head‐and‐neck cancer in carbon ion radiotherapy: A literature review, Maria Varnava, Atsushi Musha, Mutsumi Tashiro, Nobuteru Kubo, Naoko Okano, Hidemasa Kawamura, Tatsuya Ohno, No, No, No, Feb. 2023, Cancer Medicine, Scientific journal

Development and Applications of Compton Camera-A Review., Parajuli Raj Kumar;Sakai Makoto;Parajuli Ramila;Tashiro Mutsumi, No, Yes, No, 28 Sep. 2022, Sensors (Basel, Switzerland), 22, 19, Scientific journal

Linear energy transfer-independent calibration of radiochromic film for carbon-ion beams, Mutsumi Tashiro, Motohiro Kawashima, Yes, Yes, Aug. 2022, Physics and Imaging in Radiation Oncology, 23, 140, 143, Scientific journal

First Human Cell Experiments With FLASH Carbon Ions, Mutsumi Tashiro, Yukari Yoshida, Takahiro Oike, Masao Nakao, Ken Yusa, Yuka Hirota, Tatsuya Ohno, Yes, No, Yes, May 2022, Anticancer Research, 42, 5, 2469, 2477, Scientific journal

An adaptive planning strategy in carbon ion therapy of pancreatic cancer involving beam angle selection, Motohiro Kawashimaa, Mutsumi Tashiro, Maria Varnava, Shintaro Shiba, Toshiaki Matsui, Shohei Okazaki, Yang Li, Shuichiro Komatsu, Hidemasa Kawamura, Masahiko Okamoto, Tatsuya Ohno, No, No, No, Jan. 2022, Physics and Imaging in Radiation Oncology, 21, 35, 41, Scientific journal

Carbon range verification with 718 keV Compton imaging, Raj Kumar Parajuli, Makoto Sakai, Kazuo Arakawa, Yoshiki Kubota, Nobuteru Kubo, Mutsumi Tashiro, No, Yes, No, 04 Nov. 2021, Scientific Reports, 11, 21696, Scientific journal

Retrospective comparison of rectal toxicity between carbon-ion radiotherapy and intensity-modulated radiation therapy based on treatment plan, normal tissue complication probability model, and clinical outcomes in prostate cancer, Fukata, Kyohei;Kawamura, Hidemasa;Kubo, Nobuteru;Kanai, Tatsuaki;Torikoshi, Masami;Nakano, Takashi;Tashiro, Mutsumi;Ohno, Tatsuya, Oct. 2021, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 90, 6, 12

Adaptive planning based on single beam optimization in passive scattering carbon ion radiotherapy for patients with pancreatic cancer, Yang Li, Yoshiki Kubota, Masahiko Okamoto, Shintaro Shiba, Shohei Okazaki, Toshiaki Matsui, Mutsumi Tashiro, Takashi Nakano & Tatsuya Ohno, No, No, No, 19 Jun. 2021, Radiation Oncology, 16, 111

Rectal dose-sparing effect with bioabsorbable spacer placement in carbon ion radiotherapy for sacral chordoma: dosimetric comparison of a simulation study, Shintaro Shiba, Masahiko Okamoto, Mutsumi Tashiro, Hiroomi Ogawa, Katsuya Osone, Takashi Yanagawa, Isaku Kohama, Shohei Okazaki, Yuhei Miyasaka, Naoto Osu, Hirotaka Chikuda, Hiroshi Saeki, Tatsuya Ohn, No, No, No, 30 Mar. 2021, Journal of radiation research, 62, 3, 549, 555, Scientific journal

Calculation of Stopping-Power Ratio from Multiple CT Numbers Using Photon-Counting CT System: Two- and Three-Parameter-Fitting Method, Sung Hyun Lee, Naoki Sunaguchi, Akie Nagao, Yoshiyuki Hirano, Hiroshi Sakurai, Yosuke Kano, Masami Torikoshi, Tatsuaki Kanai and Mutsumi Tashiro, No, Yes, No, 09 Feb. 2021, Sensors, 21, 4, 1215, Scientific journal

Combined Environment Simulator for Low-Dose-Rate Radiation and Partial Gravity of Moon and Mars, Akihisa Takahashi; Sakuya Yamanouchi; Kazuomi Takeuchi; Shogo Takahashi; Mutsumi Tashiro; Jun Hidema; Atsushi Higashitani; Takuya Adachi; Shenke Zhang; Fady Nagy Lotfy Guirguis; Yukari Yoshida; Aiko Nagamatsu; Megumi Hada; Kunihito Takeuchi; Tohru Takahashi; Yuji Sekitomi, 06 Nov. 2020, Life, 10, 11, 274, 274, Scientific journal

Reconstruction of dose distributions for fine carbon-ion beams using iterative approximation toward carbon-knife., Tashiro Mutsumi;Souda Hikaru;Yoshida Takuya;Sakurai Hiroshi, Yes, Yes, 14 Oct. 2020, Physics in Medicine and Biology, 65, 22, 225023, Scientific journal

Simultaneous determination of the dose and linear energy transfer (LET) of carbon-ion beams using radiochromic films., Kawashima Motohiro;Matsumura Akihiko;Souda Hikaru;Tashiro Mutsumi, Yes, 15 Jun. 2020, Physics in Medicine and Biology, 65, 12, 125002, Scientific journal

Crosstalk Reduction Using a Dual Energy Window Scatter Correction in Compton Imaging., Sakai Makoto;Parajuli Raj Kumar;Kubota Yoshiki;Kubo Nobuteru;Yamaguchi Mitsutaka;Nagao Yuto;Kawachi Naoki;Kikuchi Mikiko;Arakawa Kazuo;Tashiro Mutsumi, Yes, 26 Apr. 2020, Sensors (Basel, Switzerland), 20, 9, 2453, Scientific journal

Divided-volume matching technique for volume displacement estimation of patient positioning in radiation therapy, Mutsumi Tashiro; Yoshiki Kubota; Masami Torikoshi; Tatsuya Ohno; Takashi Nakano, Yes, Jun. 2019, Physica Medica, 62, 1, 12, Scientific journal

Value of three-dimensional imaging systems for image-guided carbon ion radiotherapy, Li Y; Kubota Y; Tashiro M; Ohno T, Feb. 2019, Cancers, 11, 3, 297

Evaluation of the accuracy and clinical practicality of a calculation system for patient positional displacement in carbon ion radiotherapy at five sites, Yoshiki Kubota; Hayato Hayashi; Satoshi Abe; Saki Souda; Ryosuke Okada; Takayoshi Ishii; Mutsumi Tashiro; Masami Torikoshi; Tatsuaki Kanai; Tatsuya Ohno; Takashi Nakano, 01 Mar. 2018, Journal of Applied Clinical Medical Physics, 19, 2, 144, 153, Scientific journal

Predicting dose distribution with replacing stopping power ratio for inter-fractional motion and intra-fractional motion during carbon ion radiotherapy with passive irradiation method for stage I lung cancer, Kubota Y; Sakai M; Tashiro M; Saitoh JI; Abe T; Ohno T; Nakano T, 2018, MEDICAL PHYSICS, 45, 7, 3435, 3441, Scientific journal

Margin estimation and disturbances of irradiation field in layer-stacking carbon-ion beams for respiratory moving targets, Shinya Tajiri; Mutsumi Tashiro; Tomohiro Mizukami; Chihiro Tsukishima; Masami Torikoshi; Tatsuaki Kanai, 01 Nov. 2017, Journal of Radiation Research, 58, 6, 840, 848, Scientific journal

Changes in Rectal Dose Due to Alterations in Beam Angles for Setup Uncertainty and Range Uncertainty in Carbon-Ion Radiotherapy for Prostate Cancer, Yoshiki Kubota; Hidemasa Kawamura; Makoto Sakai; Ryou Tsumuraya; Mutsumi Tashiro; Ken Yusa; Nobuteru Kubo; Hiro Sato; Masahiro Kawahara; Hiroyuki Katoh; Tatsuaki Kanai; Tatsuya Ohno; Takashi Nakano, 20 Apr. 2016, PLOS ONE, 11, 4, e0153894, e0153894, Scientific journal

Incidence, risk factors, and dose-volume relationship of radiation-induced rib fracture after carbon ion radiotherapy for lung cancer, Abe, Takanori;Shirai, Katsuyuki;Saitoh, Jun-Ichi;Ebara, Takeshi;Shimada, Hirofumi;Tashiro, Mutsumi;Okano, Naoko;Ohno, Tatsuya;Nakano, Takashi, 2016, ACTA ONCOLOGICA, 55, 2, 163, 166, Scientific journal

Development of an automatic evaluation method for patient positioning error, Yoshiki Kubota; Mutsumi Tashiro; Ayaka Shinohara; Satoshi Abe; Saki Souda; Ryosuke Okada; Takayoshi Ishii; Tatsuaki Kanai; Tatsuya Ohno; Takashi Nakano, 2015, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 16, 4, 100, 111, Scientific journal

Dosimetric analysis between carbon ion radiotherapy and stereotactic body radiotherapy in stage I lung cancer., Ebara Takeshi; Shimada Hirofumi; Kawamura Hidemasa; Shirai Katsuyuki; Saito Jun-Ichi; Kawashima Motohiro; Tashiro Mutsumi; Ohno Tatsuya; Kanai Tatsuaki; Nakano Takashi, 01 Sep. 2014, Anticancer research, 34, 9, 5099, 5104, Scientific journal

Quantitative Evaluation of the Robustness of Beam Directions Based on Power Spectral Analysis of Water-Equivalent Path Length Image in Charged Particle Therapy, Hidetaka Arimura; Genyu Kakiuchi; Yoshiyuki Shioyama; Shin-ichi Minohara; Takahiro Nakamoto; Katsumasa Nakamura; Hiroshi Honda; Mutsumi Tashiro; Tatsuaki Kanai; Hideki Hirata, 02 Jan. 2014, International Journal of Intelligent Computing in Medical Sciences & Image Processing, 6, 1, 1, 16, Scientific journal

Technical approach to individualized respiratory-gated carbon-ion therapy for mobile organs, Mutsumi Tashiro; Takayoshi Ishii; Jun-ichi Koya; Ryosuke Okada; Yuji Kurosawa; Keisuke Arai; Satoshi Abe; Yoshiaki Ohashi; Hirofumi Shimada; Ken Yusa; Tatsuaki Kanai; Satoru Yamada; Hidemasa Kawamura; Takeshi Ebara; Tatsuya Ohno; Takashi Nakano, Yes, Jul. 2013, Radiological Physics and Technology, 6, 2, 356, 366, Scientific journal

Design of ridge filters for spread-out Bragg peaks with Monte Carlo simulation in carbon ion therapy, M Sakama; T Kanai; Y Kase; K Yusa; M Tashiro; K Torikai; H Shimada; S Yamada; T Ohno; T Nakano, 21 Oct. 2012, Physics in Medicine and Biology, 57, 20, 6615, 6633, Scientific journal

Carbon Ion Radiotherapy at the Gunma University Heavy Ion Medical Center: New Facility Set-up, Tatsuya Ohno; Tatsuaki Kanai; Satoru Yamada; Ken Yusa; Mutsumi Tashiro; Hirofumi Shimada; Kota Torikai; Yukari Yoshida; Yoko Kitada; Hiroyuki Katoh; Takayoshi Ishii; Takashi Nakano, 26 Oct. 2011, Cancers, 3, 4, 4046, 4060, Scientific journal

The compact electron cyclotron resonance ion source KeiGM for the carbon ion therapy facility at Gunma University, M. Muramatsu; A. Kitagawa; A. G. Drentje; S. Hojo; T. Ueda; H. Miyazaki; K. Yusa; M. Tashiro; K. Torikai; M. Sakama; T. Kanai; S. Yamada, Feb. 2010, Review of Scientific Instruments, 81, 2, Scientific journal

Dosimetric evaluation of nuclear interaction models in the Geant4 Monte Carlo simulation toolkit for carbon-ion radiotherapy, S. Kameoka; K. Amako; G. Iwai; K. Murakami; T. Sasaki; T. Toshito; T. Yamashita; T. Aso; A. Kimura; T. Kanai; N. Kanematsu; M. Komori; Y. Takei; S. Yonai; M. Tashiro; H. Koikegami; H. Tomita; T. Koi, Jul. 2008, Radiological Physics and Technology, 1, 2, 183, 187, Scientific journal

Evaluation of beam wobbling methods for heavy-ion radiotherapy, Shunsuke Yonai; Nobuyuki Kanematsu; Masataka Komori; Tatsuaki Kanai; Yuka Takei; Osamu Takahashi; Yoshiharu Isobe; Mutsumi Tashiro; Hajime Koikegami; Hideki Tomita, 19 Feb. 2008, Medical Physics, 35, 3, 927, 938, Scientific journal

Study of annihilation processes of positrons in polystyrene-related polymers, Y. Honda; T. Shimada; M. Tashiro; N. Kimura; Y. Yoshida; G. Isoyama; S. Tagawa, Feb. 2007, RADIATION PHYSICS AND CHEMISTRY, 76, 2, 169, 171, Scientific journal

New Accelerator Facility for Carbon-Ion Cancer-Therapy, Koji NODA; Takuji FURUKAWA; Takashi FUJISAWA; Yoshiyuki IWATA; Tatsuaki KANAI; Mitsutaka KANAZAWA; Atsushi KITAGAWA; Masataka KOMORI; Shinichi MINOHARA; Takeshi MURAKAMI; Masayuki MURAMATSU; Shinji SATO; Yuka TAKEI; Mutsumi TASHIRO; Masami TORIKOSHI; Satoru YAMADA; Ken YUSA, 2007, Journal of Radiation Research, 48, Suppl.A, A43, A54, Scientific journal

Three-dimensional velocity mapping of lung motion using vessel bifurcation pattern matching, Mutsumi Tashiro; Shinichi Minohara; Tatsuaki Kanai; Ken Yusa; Hideyuki Sakurai; Takashi Nakano, Yes, 19 May 2006, Medical Physics, 33, 6Part1, 1747, 1757, Scientific journal

Formation of defect structures in Au-polysilane interfaces probed by low energy positron beams, Y Terashima; S Seki; M Tashiro; Y Hond; S Tagawa, Dec. 2004, SOLID STATE COMMUNICATIONS, 132, 9, 641, 645, Scientific journal

Study of Interfaces in Polymer Bilayers by Slow Positron Beam, Y. Terashima; S. Seki; K. Miyamoto; M. Tashiro; Yoshihide Honda; Seiichi Tagawa, Jan. 2004, Materials Science Forum, 445-446, 349, 351, Scientific journal

Influence of radiation-induced species on positronium formation in poly(methylmethacrylate) at low temperature, M. Tashiro; C.Y. Tseng; S. Seki; Y. Honda; S. Tagawa, Oct. 2003, Radiation Physics and Chemistry, 68, 3-4, 475, 479, Scientific journal

Behavior of positronium in polystyrene and its derivatives, Y Honda; M Watanabe; M Tashiro; Y Terashima; K Miyamoto; N Kimura; S Tagawa, Oct. 2003, RADIATION PHYSICS AND CHEMISTRY, 68, 3-4, 463, 465, Scientific journal

The effects of free volumes on charge carrier transport in polysilanes probed by positron annihilation, S Seki; Y Terashima; Y Kunimi; T Kawamori; M Tashiro; Y Honda; S Tagawa, Oct. 2003, RADIATION PHYSICS AND CHEMISTRY, 68, 3-4, 501, 505, Scientific journal

The study of nano-space in polyhydroxystyrene/polystyrene bilayer by slow positron beam, Y Terashima; M Tashiro; K Miyamoto; Y Honda; S Tagawa, Oct. 2003, RADIATION PHYSICS AND CHEMISTRY, 68, 3-4, 589, 592, Scientific journal

Study of nano-space in Au-polysilane interfaces by slow positron beam, Y Terashima; S Seki; M Tashiro; Y Honda; S Tagawa, 2003, JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, 16, 3, 445, 446, Scientific journal

The interaction between polymer thin films and positron from slow positron beam, K Miyamoto; Y Terashima; M Tashiro; Y Honda; S Tagawa, 2003, JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, 16, 3, 411, 412, Scientific journal

Study of interfaces in polymer bilayers using slow positron beam, M Tashiro; Y Honda; Y Terashima; M Watanabe; P.K Pujari; S Tagawa, Jun. 2002, Applied Surface Science, 194, 1-4, 182, 188, Scientific journal

Development of a Pulsing System with the Linac Based Slow Positron Beam, M. Tashiro; Yoshihide Honda; T. Yamaguchi; P.K. Pujari; N. Kimura; T. Kozawa; Seiichi Tagawa, Yes, Apr. 2001, Materials Science Forum, 363-365, 664, 666, Scientific journal

Development of a New Positron Beam for Coincident Studies with Laser Excitation, Yoshihide Honda; M. Tashiro; T. Yamaguchi; P.K. Pujari; N. Kimura; T. Kozawa; S. Nishijima; G. Isoyama; Seiichi Tagawa, Apr. 2001, Materials Science Forum, 363-365, 667, 669, Scientific journal

Study of Buried Polymer-Polymer Interfaces Using Slow Positron Beams, P.K. Pujari; M. Tashiro; Yoshihide Honda; Ryoichi Suzuki; Seiichi Tagawa, Apr. 2001, Materials Science Forum, 363-365, 618, 620, Scientific journal

Low Temperature Positron Studies in Polymethylmethacrylate, P.K. Pujari; M. Tashiro; C.Y. Tseng; Yoshihide Honda; S. Nishijima; Seiichi Tagawa, Apr. 2001, Materials Science Forum, 363-365, 275, 277, Scientific journal

Development of a short-pulsed slow positron beam for application to polymer films, M. Tashiro; Y. Honda; T. Yamaguchi; P.K. Pujari; N. Kimura; T. Kozawa; G. Isoyama; S. Tagawa, Yes, Jan. 2001, Radiation Physics and Chemistry, 60, 4-5, 529, 533, Scientific journal

Studies on thermally induced structural changes in silicon based polymers by positron annihilation, Mutsumi Tashiro; Pradeep K Pujari; Shu Seki; Yoshihide Honda; Shigehiro Nishijima; Seiichi Tagawa, Yes, Jun. 2000, Radiation Physics and Chemistry, 58, 5-6, 587, 592, Scientific journal

Free Volume in Poly(n-alkylphenylsilane) Probed by Positron Annihilation., Yoshihisa KUNIMI; Shu SEKI; Mutsumi TASHIRO; Seiichi TAGAWA, 2000, Journal of Photopolymer Science and Technology, 13, 5, 723, 728, Scientific journal

Free-volume Characterization of Polysilanes Using Positron Annihilation Spectroscopy., Mutsumi Tashiro; Shu Seki; Pradeep K. Pujari; Yoshihide Honda; Seiichi Tagawa, Yes, 1999, Journal of Photopolymer Science and Technology, 12, 5, 739, 742, Scientific journal

Studies on the Thin Films of Poly(di-n-hexylsilane) Using Slow Positron Beam Technique., Mutsumi Tashiro; Pradeep K. Pujari; Shu Seki; Yoshihide Honda; Tomohiro Yamaguchi; Ryoichi Suzuki; Seiichi Tagawa, 1999, Journal of Photopolymer Science and Technology, 12, 5, 743, 745, Scientific journal

Reemitted spin-polarized slow-positron spectroscopy in Fe/Cu multilayers, Terunobu Nakajyo; Mutsumi Tashiro; Tomoya Koizumi; Ikuzo Kanazawa; Fumio Komori; Yasuo Ito, Oct. 1997, Radiation Physics and Chemistry, 50, 4, 315, 320, Scientific journal

The Positron-Induced Ion-Desorption Spectroscopy, Ikuzo Kanazawa; T. Koizumi; A. Iwamoto; M. Tashiro; F. Komori; Y. Murata; K. Fukutani; Yasuo Ito, Sep. 1997, Materials Science Forum, 255-257, 787, 789, Scientific journal

The Study of the Thin Magnetic Film Fe and Multilayer Fe/Hf with the Slow Positron Beam, T. Koizumi; A. Iwamoto; H. Ohtaki; Y. Murashige; M. Tashiro; Ikuzo Kanazawa; F. Komori; Yasuo Ito, Sep. 1997, Materials Science Forum, 255-257, 626, 628, Scientific journal

The study of multilayers Fe/Hf and Ni/Hf by slow positron beam technique, Mutsumi Tashiro; Terunobu Nakajyo; Yusuke Murashige; Tomoya Koizumi; Ikuzo Kanazawa; Fumio Komori; We-Hyo Soe; Ryoichi Yamamoto; Yasuo Ito, Yes, May 1997, Applied Surface Science, 116, 263, 267, Scientific journal

The spin polarized slow positron beam and the reemitted polarized slow positron spectroscopy, Terunobu Nakajyo; Mutsumi Tashiro; Tomoya Koizumi; Ikuzo Kanazawa; Fumio Komori; Yasuo Ito, May 1997, Applied Surface Science, 116, 168, 176, Scientific journal

The electrostatic slow positron beam for the positron-induced ion-desorption spectroscopy, Ikuzo Kanazawa; Terunobu Nakajyo; Mutsumi Tashiro; Fumio Komori; Yoshitada Murata; Katsuyuki Fukutani; Yasuo Ito, May 1997, Applied Surface Science, 116, 129, 133, Scientific journal

The multilayer studied with slow positron beam, Y. Murashige; M. Tashiro; T. Nakajyo; T. Koizumi; I. Kanazawa; F. Komori; Y. Ito, Apr. 1997, Applied Surface Science, 113-114, 169, 173, Scientific journal

Feb. 2008, 58, 1, 107, 107

Yes, Yes, Aug. 2008, 58, 3, 343, 343

Aug. 2018, 68, 3, 178

Oct. 2020, 63, 22

Yes, Aug. 2021, 71, 3, 235

Yes, Aug. 2021, 71, 3, 235

Introduction of Gunma University Heavy Ion Medical Center, Mutsumi TASHIRO, Yes, Yes, Yes, 30 Sep. 2021, Japanese Journal of Medical Physics, 41, 3, 161, 165, Introduction scientific journal

Present Status of Gunma University Heavy Ion Medical Center, Hikaru Souda; Haruka Kikuchi; Ken Yusa; Tashiro Mutsumi; Hirofumi Shimada; Akihiko Matsumura; Yoshiki Kubota; Tatsuaki Kanai; Masami Torikoshi, 2017, Proceedings of the 14th Annual Meeting of Particle Accelerator Society of Japan

Operation-Pattern Related Beam Fluctuation in a Heavy Ion Synchrotron, Hikaru Souda; Ken Yusa; Mutsumi Tashiro; Hirofumi Shimada; Akihiko Matsumura; Yoshiki Kubota; Masami Torikoshi, 2016, Japanese Journal of Medical Physics, 36, Sup3, 184

Improvement of Scanning Irradiation In Gunma University Heavy Ion Medical Center, H. Souda; T. Fujimoto; H. Kikuchi; K. Torikai; K. Yusa; M. Tashiro; H. Shimada; A. Matsumura; Y. Kubota; E. Takeshita; S. Yamada; T. Kanai; M. Torikoshi, 2016, Proc. of IPAC16

Development of vaginal Insertion Spacer That Verifies The Position and Dose Distribution in CIRT Uterine Cervix, Yoshiki Kubota; Tatsuya Ohno; Kazutoshi Murata; Makoto Sakai; Kazutoshi Tsuda; Mutsumi Tashiro; Shin-ei Noda; Masami Torikoshi; Tatsuaki Kanai; Takashi Nakano, 2016, GUMI AND AMDE 2016, 44

01 May 2015, 65, 2, 170, 170

Development of Scanning Irradiation in Gunma University Heavy Ion Medical Center, Hikaru Souda; Tatsuaki Kanai; Satoru Yamada; Tetsuya Fujimoto; Yoshiki Kubota; Ken Yusa; Mutsumi Tashiro; Hirofumi Shimada; Akihiko Matsumura; Akito Saito; Kyohei Fukata; Kota Torikai; Eri Takeshita; Yosuke Kano; Kazushi Hanakawa; Yoshikazu Ishikawa; Yasuto Kishii; Taizo Honda; Yusuke Sakamoto, 2014, Proceedings of the 11th Annual Meeting of Particle Accelerator Society of Japan, 890, 892

Extracted Beam Control by Dynamic Bump in Synchrotron, Kota Torikai; Satoru Yamada; Tatsuaki Kanai; Hikaru Sohda; Ken Yusa; Mutsumi Tashiro; Yoshiki Kubota; Akihiko Matsumura; Hirofumi Shimada; Eri Takeshita, 2013, Proceedings of the 10th Annual Meeting of Particle Accelerator Society of Japan, 130, 131

Present Status of Gunma University Heavy Ion Medical Center, Hikaru Souda; Satoru Yamada; Tatsuaki Kanai; Ken Yusa; Mutsumi Tashiro; Hirofumi Shimada; Yoshiki Kubota; Akihiko Matsumura; Akito Saito; Kota Torikai; Tetsuya Fujimoto; Eri Takeshita, 2013, Proceedings of the 10th Annual Meeting of Particle Accelerator Society of Japan, 363, 366

2012, 32, Sup. 1, 193

Sub-mm Therapeutic Carbon-Ion Irradiation Port in Gunma University, Kota Torikai; Tatuaki Kanai; Takashi Nakano; Hirofumi Shimada; Eri Takeshita; Mutsumi Tashiro; Satoru Yamada; Ken Yusa; Gunma University; Maebashi-Gunma; Kazushi Hanakawa; Taizo Honda; Katsuhisa Yoshida; Mitsubishi Electric Corporation, Kob, 2011, Proc. Of 2nd International Particle Accelerator Conference, THPS076

2010, 32, 140, 141

2010, 32

2010, 32, 101, 102

2010, 32, 144, 145

2010, 30, Sup.2, 142, 143

2009, 146-147, Summary national conference

2009

2009, 29, Sup.3, 215, 216

CONSTRUCTION STATUS OF HEAVY-ION RADIOTHERAPY FACILITY AT GUNMA UNIVERSITY (II), Ken Yusa; Mutsumi Tashiro; Kota Torikai; Tatsuya Ohno; Satoru Yamada, 2008, Proceedings of the 5th Annual Meeting of Particle Accelerator Society of Japan and the 33rd Linear Accelerator Meeting in Japan

2007, Vol.27, No.4, 187, 188

Quantitative evaluation of 3D lung motion with anatomical feature tracking technique for precise particle radiotherapy, M Tashiro; S Minohara; K Yusa; H Sakurai; T Kanai; M Baba; T Miyamoto; T Nakano, Mar. 2006, RADIOTHERAPY AND ONCOLOGY, 78, S85, S86, Summary international conference

First Experimental Results of Spiral-Wobbler System for Heavy-Ion Radiotherapy, M. Komori; T. Kanai; N. Kanematsu; Y. Kobayashi; S. Yonai; Y. Kusano; T. Nakajima; O. Takahashi; M. Tashiro; Y. Ihara; H. Koikegami, 2005, Proceedings of The 4th Japan-Korea Joint Meeting on Medical Physics and The 5th Asia-Oceania Congress of Medical Physics, Part2, 164-166

01 May 2015, 65, 2, 164, 164

Treatment Planning, Mutsumi TASHIRO, Hirofumi SHIMADA, Motohiro KAWASHIMA, Yes, No, Yes, 2015, RADIOISOTOPES, 64, 6, 394, 399, Introduction scientific journal

Radiation Control and Protection, Mutsumi TASHIRO, 2015, RADIOISOTOPES, 64, 6, 406, 408, Introduction scientific journal

2015, 65, 2

Introduction of Gunma University Heavy Ion Medical Center, Mutsumi TASHIRO, Yes, Yes, Oct. 2012, Radiation Chemistry, 92, 33, 37, Introduction scientific journal

2012, 32, 1

2011, 26, 3, 49, 51, Introduction commerce magazine

01 Feb. 2009, 59, 1, 74, 74

01 Feb. 2007, 57, 1, 66, 66

2004, 77, 36, 40

01 Nov. 2000, 63, 16, 20

Construction of the Short-Pulsed Slow Positron Beam in ISIR, TASHIRO M.; YAMAGUCHI T.; HONDA Y.; KIMURA N.; KOZAWA T.; NISHIJIMA S.; TAGAWA S., 05 Sep. 1998, Meeting abstracts of the Physical Society of Japan, 53, 2, 432, 432

01 Oct. 2026, 01 Oct. 2026, 02 Oct. 2026, Japan, Domestic conference

LET and Clinical Outcomes in Carbon-Ion Radiotherapy, Mutsumi Tashiro, The 26th Asia-Oceania Congress of Medical Physics (AOCMP 2026), 11 Sep. 2026, 09 Sep. 2026, 11 Sep. 2026, Busan Port International Exhibition & Convention Center (BPEX), Korea, Republic of, International conference

Development of the Carbon FLASH Irradiation System and Its Preclinical Biological Evaluation at GHMC, Mutsumi Tashiro, 2026 FLASH Radiotherapy Symposium, 28 Apr. 2026, 28 Apr. 2026, 28 Apr. 2026, Seoul, Korea, Republic of, International conference

31 Jan. 2026

Development of a 3D FLASH Carbon-Ion Irradiation System for Animal Studies, Mutsumi Tashiro, Shunsuke Inagaki, Naoto Urabe, Tanny Bepari, Masao Nakao, Ken Yusa, Yukari Yoshida, Tatsuya Ohno, The 5th Annual Conference of Asia-Oceania Particle Therapy Co-Operative Group (PTCOG-AO 2025), 08 Nov. 2025, 07 Nov. 2025, 09 Nov. 2025, Hong Kong, Hong Kong, International conference

Development of Carbon Ion Irradiation Planning Software for small Targets of small Animal Experiments, Shunsuke Inagaki, Mutsumi Tashiro, The 5th Annual Conference of Asia-Oceania Particle Therapy Co-Operative Group (PTCOG-AO 2025), 08 Nov. 2025, 07 Nov. 2025, 09 Nov. 2025, Hong Kong, Hong Kong, International conference

Study on the impact of temporal parameters on dose uniformity in layer-stacking irradiation with carbon-ion beams, Yuki Furuta, Mutsumi Tashiro, Hiroshi Sakurai, The 5th Annual Conference of Asia-Oceania Particle Therapy Co-Operative Group (PTCOG-AO 2025), 08 Nov. 2025, 07 Nov. 2025, 09 Nov. 2025, Hong Kong, Hong Kong, International conference

Development of a 3D-Printed Range Modulator for Animal Irradiation with Carbon Ion Beam Irradiation, Tanny Bepari, Mutsumi Tashiro, Tomoya Umakoshi, nBHEAM 2025: Neutron Beams at High Energy: Applications and Metrology, 07 Jul. 2025, 07 Jul. 2025, 08 Jul. 2025, IAEA Headquarter, Vienna, Austria, International conference

Development of a 3D-Printed Range Modulator for Animal Irradiation with Carbon Ion Beam Irradiation, Tanny Bepari, Tomoya Umakoshi, Shunsuke Inagaki, Mutsumi Tashiro, FLASH Workshop 2025: The Role of Oxygen in FLASH Radiation Therapy, 03 Jul. 2025, 01 Jul. 2025, 03 Jul. 2025, Heidelberg, Germany, International conference

The development of carbon ion dose distribution optimization software for small animal irradiation planning, Shunsuke Inagaki, Mutsumi Tashiro, International Conferences of Mini Micro Nano Dosimetry (MMND 2025) in conjunction with Innovation Technologies in Radiation Oncology (ITRO 2025), 18 Feb. 2025, 18 Feb. 2025, 22 Feb. 2025, Sydney, Australia, International conference

Evaluation of respiratory motion tolerance for layer-stacking conformal carbon-ion radiotherapy, Yuki Hasebe, Mutsumi Tashiro, Hiroshi Sakurai, The 10th Japan-Korea Joint Meeting on Medical Physics, 21 Sep. 2024, 20 Sep. 2024, 22 Sep. 2024, Nagoya, Japan, International conference

Development of 3D range modulators using a 3D printer for animal irradiation with carbon ion beams, Tomoya Umakoshi, Shunsuke Inagaki ,Mutsumi Tashiro, The 10th Japan-Korea Joint Meeting on Medical Physics, 21 Sep. 2024, 20 Sep. 2024, 22 Sep. 2024, Nagoya, Japan, International conference

Development of carbon ion dose distribution calculation and optimization software for small animals, Shunsuke Inagaki, Mutsumi Tashiro, The 10th Japan-Korea Joint Meeting on Medical Physics, 21 Sep. 2024, 20 Sep. 2024, 22 Sep. 2024, Nagoya, Japan, International conference

06 Jan. 2024, 06 Jan. 2024, 06 Jan. 2024, Japan

Current status of carbon ion FLASH, Mutsumi Tashiro, The 126th Scientific Meeting of the JSMP, 17 Sep. 2023, 15 Sep. 2023, 17 Sep. 2023, Hiroshima, Japan

FLASH Carbon-Ion Irradiation System Development for Human Cell Experiments, Mutsumi Tashiro, The 2nd Annual Conference of the Asia-Oceania Particle Therapy Co-Operative Group (PTCOF-AO 2022)), 03 Dec. 2022, 02 Dec. 2022, 03 Dec. 2022, Jeju ICC, Jeju, Korea, Korea, Republic of, International conference

FLASH carbon-ion irradiation system establishment and human cell experiments, Mutsumi Tashiro, Yukari Yoshida, Takahiro Oike, Masao Nakao, Ken Yusa, Yuka Hirota, Tatsuya Ohno, Flash Radiotherapy & Particle Therapy Conference (FRPT 2022), 30 Nov. 2022, 30 Nov. 2022, 02 Dec. 2022, Barcelona, Spain and Online, International conference

Establishment of FLASH carbon-ion irradiation system and cell irradiation examinations, Mutsumi Tashiro, Yukari Yoshida, Takahiro Oike, Masao Nakao, Ken Yusa, Yuka Hirota, Tatsuya Ohno, The 124th congress of Japanese Society of Medical Physics, 16 Sep. 2022, 15 Sep. 2022, 17 Sep. 2022

Dosimetry of experimental carbon-ion mini-beams toward ‘Carbon-Knife’ and ‘Carbon-Flash’, M. Tashiro, M. Nakao, Y. Yoshida, K. Yusa, T. Ohno, Flash Radiotherapy & Particle Therapy (FRPT) 2021, 01 Dec. 2021, 01 Dec. 2021, 03 Dec. 2021, Austria, International conference

Reconstruction of lateral dose distributions with optimized filtering process for fine carbon-ion beams toward ‘carbon-knife’, Mutsumi Tashiro, Hikaru Souda, Hiroshi Sakurai, 59th Annual Conference of the Particle Therapy Co-Operative Group (PTCOG 59), 07 Jun. 2021, 04 Jun. 2021, 07 Jun. 2021, International conference

20 May 2021, 19 May 2021, 21 May 2021, Japan

Iterative reconstruction of lateral dose distributions for fine carbon-ion beams toward 'Carbon-Knife', M. Tashiro, H. Souda, T. Yoshida, H. Sakurai, The 10th International Society of Radiation Neurobiology Conference ISRN-2020, 13 Mar. 2020, English, International conference

24 Jan. 2020, 23 Jan. 2020, 24 Jan. 2020

Reconstruction of dose distributions for fine carbon-ion beams toward "Carbon Knife", M. Tashiro, H. Souda, T. Yoshida, H. Sakurai, 3rd International Conference on Mechanical, Electrical and Medical Intelligent System (ICMEMIS 2019), 04 Dec. 2019, 04 Dec. 2019, 06 Dec. 2019, English, International conference

Filtering process examination for dose distribution reconstruction of fine carbonion beams using iterative approximation, Mutsumi Tashiro, Hikaru Souda, Takuya Yoshida, Hiroshi Sakurai, The 118th Congress on Japan Society of Medical Physics, 12 Sep. 2019, 12 Sep. 2019, 15 Sep. 2019, Japanese, Domestic conference

Divided-volume matching technique for volume displacement estimation at patient positioning, Mutsumi Tashiro, Yoshiki Kubota, Tatsuya Ohno, The 118th Congress on Japan Society of Medical Physics, 12 Sep. 2019, 12 Sep. 2019, 15 Sep. 2019, Japanese, Fukui, Japan, Domestic conference

Dose distribution reconstruction of fine carbon-ion beams for carbon-knife, 57th Annual Conference of the Particle Therapy Co-operative Group (PTCOG57), 2018

2018

2018

Development of Multi-Volume Matching technique for segment displacement estimation at patient positioning, 8th Japan-Korea Joint Meeting on Medical Physics, 2017

Technical approach to individualized respiratory-gated carbon-ion therapy for mobile organs, JRC2014, 13 Apr. 2014

Respiratory motion management for carbon-ion therapy at GHMC, The 2nd International Symposium of Gunma University Program for Leading Graduate Schools, 2014

2014

Investigation of Respiratory-Gated Carbon Treatment Planning Using Motion-Included Dose Distribution, 51st Annual Meeting of Particle Therapy Co-Operative Group (PTCOG51), 2012

INVESTIGATION OF RESPIRATORY-GATED CARBON TREATMENT USING MOTION-INCLUDED DOSE DISTRIBUTION, The 31st Sapporo International Cancer Symposium Advanced Radiation Therapy and Cancer Research, 2012

2012

2012

Technical approach and validation of respiratory-gated carbon-ion therapy for mobile organs at Gunma University, The Annual PTCOG 50 meeting, 2011

2011

Preclinical physical assessment on positioning, respiratory-gating and dosimetry for carbon-ion therapy at GHMC, 49th Annual Meeting of the Particle Therapy Co-Operative Group, 2010

2010

2010

2010

2009

2009

2008

2008

2008

2008

Status of Construction of Carbon Ion Radiation Therapy Facility in Gunma University, Ken YUSA; Mutsumi TASHIRO; Tatsuya OHNO; Satoru YAMADA; Takashi NAKANO; Seiji OZAWA, 29 Sep. 2007

A New Carbon-Ion Treatment Facility at Gunma University, Workshop on Innovative Techniques for Hadrontherapy in The 2007 IEEE Nuclear Science Symposium (NSS) and Medical Imaging Conference (MIC), 2007

Progress in the Construction of the Facility at Gunma University Heavy Ion Medical Center (GHMC), Particle Therapy Co-Operative Group 46, 2007

2007

2007

2007

Quantitative evaluation of 3D lung motion with anatomical feature tracking technique for precise particle radiotherapy, Third International Conference on Translational Research, 2006

2006

2006

Quantification Technique of 3D Lung Motion Using Vessel Bifurcation Pattern Matching, The 4th Japan-Korea Joint Meeting on Medical Physics and The 5th Asia-Oceania Congress of Medical Physics, 2005

Quantitative evaluation technique for 3D lung motion using anatomical feature tracking, 43rd International Meeting of Particle Therapy Co-Operative Group, 2005

2005

Patent right, Patient positioning support device, 特願2017-31732, 23 Feb. 2017, ; , 特開2018-134290, 30 Aug. 2018, 特許-第6800462号, 27 Nov. 2020, 27 Nov. 2020, No, No

Patent right, Intracavitary spacer for radiation therapy, 特願2014-156988, 31 Jul. 2014, ; , 特開2016-32595, 10 Mar. 2016, 特許第6651122号, 24 Jan. 2020, 24 Jan. 2020

Patent right, Multipurpose phantom and its method of using, 特願2010-112300, 14 May 2010, ; , 特開2011-239830, 01 Dec. 2011, 特許第5613925号, 19 Sep. 2014, 19 Sep. 2014

Patent right, METHOD FOR QUANTIFYING ORGAN MOTION, APPARATUS THEREFOR, METHOD FOR ESTIMATING ORGAN POSITION, APPARATUS THEREFOR, METHOD FOR IRRADIATING RADIATION, APPARATUS THEREFOR, AND APPARATUS FOR DETECTING ABN, Mutsumi Tashiro; Shin-ichi Minohara, 特願2005-141880, 13 May 2005, National Institute of Radiological Sciences; National University Corporation Gunma University, 特開2006-314643, 24 Nov. 2006, 特許第3932303号, 30 Mar. 2007, 30 Mar. 2007, Yes, Yes, Yes

Patent right, -

Patent right, METHOD FOR QUANTIFYING ORGAN MOTION, APPARATUS THEREFOR, METHOD FOR ESTIMATING ORGAN POSITION, APPARATUS THEREFOR, METHOD FOR IRRADIATING RADIATION, APPARATUS THEREFOR, AND APPARATUS FOR DETECTING ABNORMAL ORGAN TECHNICAL FIELD, -

Fighting-spirit award, Hiroyuki Katoh, Mutsumi Tashiro, International Training Cource on Carbon-ion Radiotherapy, Jan. 2017, International society

Silver Prize, Mutsumi Tashiro, Kyohei Fukata, Akihiko Matsumura, Hikaru Souda, Shintaro Takebea, International Training Cource on Carbon-ion Radiotherapy, Nov. 2013, International society

Outstanding Reviewer Award, Mutsumi Tashiro, Outstanding Reviewer Award (Outstanding Reviewer in 2020), Radiological Physics and Technology, 16 Apr. 2021, Official journal, Japan

Poster Award (Radiation Therapy), Quantification Technique of 3D Lung Motion Using Vessel Bifurcation Pattern Matching, The 4th Japan-Korea Joint Meeting on Medical Physics and The 5th Asia-Oceania Congress of Medical Physics, 30 Sep. 2005

Radiological Physics and Technology, Doi Award in Radiation Therapy Physics, Technical approach to individualized respiratory-gated carbon-ion therapy for mobile organs, Japanese Society of Radiological Technology, Japan Society of Medical Physics, 13 Apr. 2014

Apr. 2022, Mar. 2026, Principal investigator, 22K07712

Apr. 2018, Mar. 2024, Principal investigator, 18K07744

Apr. 2022, Mar. 2025, Coinvestigator, 22H02103

Oct. 2021, Mar. 2025, Coinvestigator, 21KK0095

Study on quantification and visualization of displacement of divided regions on patient positioning in heavy-ion therapy, Tashiro Mutsumi; KUBOTA Yoshiki; HAYASHI Hayato, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gunma University, 01 Apr. 2013, 31 Mar. 2017, This study aims development of automatic patient positioning software for radiotherapy and further development of a function to quantify and visualize the displacement of separated parts in patient bodies by dividing the images. We developed a “Multi-Volume Matching” technique based on our 2D-3D patient positioning software. In this technique, a 3D-CT volume was divided into multi-volumes such as a volume of interest (VOI) and a base volume (BV). The VOI was segmented so as to include structure whose motion appears in X-ray images. Then, 2D-3D matching was processed using X-ray images and Digitally Reconstructed Radiographs, which were repeatedly generated by changing 3D positions and angles of VOI and BV independently to match most with the X-ray images. Using this technique, we could visualize and quantify the displacement of VOI, as well as bony structure of the base body., 25461904, url

Nov. 2012, Oct. 2013, Principal investigator, Competitive research funding

Aug. 2011, Mar. 2012, Principal investigator, Competitive research funding

Study on high-precision carbon-ion treatment for tumors with respiratory motion by 4-dimensional treatment planning, TASHIRO Mutsumi, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Gunma University, 2011, 2012, The system environment has been created, which can deal with actual clinical CT data using a deformable fusion (registration) software for the respiratory motion evaluation with 4DCT images. A treatment-planning support tool has been also installed to be able to calculate dose distributions for a number of 3DCT images (4DCT image) at one time with an identical treatment plan condition. By use of these tools, accumulated dose distributions could be derived for CT images with different patient positions and/or with respiratory motion and deformation by considering such motion and deformation. Target dose coverage with motion and deformation could be evaluated., 23791397, url

Study on quantitative evaluation of respiratory-induced organ motion and high-precision particle cancer therapy, TASHIRO Mutsumi, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Gunma University, 2008, 2009, Lung motion evaluation techniques have been studied using CT images in order to make highly precise radiation/particle therapy for lung cancer with respiratory motion. The extraction methods of lung areas and vessels with realistic CT images, which would influence on the motion tracking accuracy, have been investigated, and the unnecessarily fine structure extraction of lung borders and vessels could be suppressed. Verification on respiratory gated-irradiation of heavy-ion therapy for lung tumors has been carried out to realize the high-precision therapy. Particularly, investigations have been carried out on evaluation of motion errors and margins, and how to deal with the margins in heavy-ion treatment planning system. The validity has been verified by beam tests with a motion phantom., 20790878, url

2000, 2002, 00J01484