Researcher Database

YAMAZAKI Yuichi
Gastroenterology and Hepatology Medicine
Lecturer
Last Updated :2025/05/07

Researcher Profile and Settings

Researcher

  • Name

    YAMAZAKI Yuichi

Profile and Settings

  • Name

    Yamazaki, Yuichi

Affiliation

  • Gunma University, Associate Professor, Associate Professor

Degree

  • MD
  • MD
  • MD
  • MD, Gunma University

Association Memberships

  • Jan. 2021, Dec. 2022

Research Experience

  • 2008, 2010, NIH/NIEHS
  • 2008, 2010

Research Activities

Research Areas

  • Life sciences, Gastroenterology

Published Papers

  • 群馬県における2019年のE型肝炎症例の特徴 同一3a型株による小流行, 山崎 勇一; 植原 大介; 金山 雄樹; 須賀 孝慶; 上野 敬史; 畑中 健; 高草木 智史; 戸島 洋貴; 滝澤 大地; 長沼 篤; 小曽根 隆; 中島 弘明; 佐藤 賢; 柿崎 暁; 高木 均; 浦岡 俊夫; 高橋 雅春; 長嶋 茂雄; 岡本 宏明, Sep. 2020, 61, 9, 478, 481
  • Ipragliflozin-induced improvement of liver steatosis in obese mice may involve sirtuin signaling., Takayoshi Suga; Ken Sato; Tatsuya Ohyama; Sho Matsui; Takeshi Kobayashi; Hiroki Tojima; Norio Horiguchi; Yuichi Yamazaki; Satoru Kakizaki; Ayaka Nishikido; Takashi Okamura; Masanobu Yamada; Tadahiro Kitamura; Toshio Uraoka, 27 Jul. 2020, World journal of hepatology, 12, 7, 350, 362, Scientific journal
  • Sofosbuvir/Ribavirin therapy for patients experiencing failure of ombitasvir/paritaprevir/ritonavir + ribavirin therapy: Two cases report and review of literature., Ken Sato; Yuichi Yamazaki; Takeshi Kobayashi; Satoshi Takakusagi; Norio Horiguchi; Satoru Kakizaki; Masayasu Andou; Yoshihiro Matsuda; Toshio Uraoka; Hiroshi Ohnishi; Hiroaki Okamoto, 06 May 2019, World journal of clinical cases, 7, 9, 1043, 1052, Scientific journal
  • Long-term Results of Bariatric Surgery for Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis Treatment in Morbidly Obese Japanese Patients., Uehara D; Seki Y; Kakizaki S; Horiguchi N; Tojima H; Yamazaki Y; Sato K; Yamada M; Uraoka T; Kasama K, Apr. 2019, Obesity surgery, 29, 4, 1195, 1201, Scientific journal
  • Constitutive androstane receptor and pregnane X receptor cooperatively ameliorate DSS-induced colitis., Daisuke Uehara; Hiroki Tojima; Satoru Kakizaki; Yuichi Yamazaki; Norio Horiguchi; Daichi Takizawa; Ken Sato; Masanobu Yamada; Toshio Uraoka, Feb. 2019, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 51, 2, 226, 235, Scientific journal
  • Non-invasive prediction of non-alcoholic steatohepatitis in Japanese patients with morbid obesity by artificial intelligence using rule extraction technology., Daisuke Uehara; Yoichi Hayashi; Yosuke Seki; Satoru Kakizaki; Norio Horiguchi; Hiroki Tojima; Yuichi Yamazaki; Ken Sato; Kazuki Yasuda; Masanobu Yamada; Toshio Uraoka; Kazunori Kasama, 27 Dec. 2018, World journal of hepatology, 10, 12, 934, 943, Scientific journal
  • A real-world clinical application of the combination therapy with glecaprevir/pibrentasvir to special population in chronic hepatitis C patients, Sato Ken; Yamazaki Yuichi; Kobayashi Takeshi; Tojima Hiroaki; Horiguchi Norio; Kakizaki Satoru; Uraoka Toshio; Ohnishi Hiroshi; Okamoto Hiroaki, Nov. 2018, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 33, 444, 444
  • Improvement of Proteinuria due to Combination Therapy with Daclatasvir and Asunaprevir in Hepatitis C Virus-associated Renal Disease without Cryoglobulinemia, Takakusagi, Satoshi; Sato, Ken; Suzuki, Yuhei; Yamazaki, Yuichi; Kosone, Takashi; Kakizaki, Satoru; Kusano, Motoyasu; Takagi, Hitoshi, 2018, INTERNAL MEDICINE, 57, 15, 2189, 2195, Scientific journal
  • A patient with type I Gaucher disease who switched from enzyme replacement therapy to substrate reduction therapy after having of CYP2D6 polymorphisms checked, Kakizaki Satoru; Otsu Yoshiaki; Ida Hiroyuki; Horiguchi Norio; Uehara Daisuke; Kanayama Yuuki; Kobayashi Takeshi; Tojima Hiroki; Yamazaki Yuichi; Sato Ken; Uraoka Toshio, 01 Jan. 2018, Kanzo, 59, 5, 243, 251, Scientific journal
  • Therapy with ombitasvir/paritaprevir/ritonavir for dialysis patients with hepatitis C, Sato Ken; Yamazaki Yuichi; Kobayashi Takeshi; Takakusagi Satoshi; Horiguchi Norio; Kakizaki Satoru; Kusano Motoyasu; Yamada Masanobu, Nov. 2016, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31, 377, 377
  • [A Case of Transfusion-transmitted Acute Hepatitis E]., Kobayashi T; Sato K; Yamazaki Y; Ohyama T; Horiguchi N; Kakizaki S; Kusano M; Yamada M; Yokohama A; Okamoto H, Nov. 2016, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 105, 11, 2215, 2220, Scientific journal
  • Elevated Serum Uric Acid Level Was a Notable Adverse Event of the Combination Therapy With Sofosbuvir and Ribavirin, Sato Ken; Naganuma Atsushi; Nagashima Tamon; Horiuchi Katsuhiko; Hoshino Takashi; Arai Yosuke; Yuasa Kazuhisa; Uehara Daisuke; Hashizume Hiroaki; Kobayashi Takeshi; Ohyama Tatsuya; Horiguchi Norio; Yamazaki Yuichi; Kakizaki Satoru; Kusano Motoyasu; Yamada Masanobu, Apr. 2016, GASTROENTEROLOGY, 150, 4, S1107, S1107
  • トシリズマブで治療中にE型肝炎を発症した関節リウマチの一例, 中沢 佳奈; 池内 秀和; 内山 和彦; 浜谷 博子; 坂入 徹; 金子 和光; 前嶋 明人; 廣村 桂樹; 山崎 勇一; 岡本 宏明; 野島 美久, Mar. 2016, 49, 49, 96, 102
  • Three cases of the hepatitis C patients that presented hyperkalemia during daclatasvir and asunaprevir combination therapy, Ohyama Tatsuya; Yamazaki Yuichi; Hashizume Hiroaki; Horiguchi Norio; Sato Ken; Kakizaki Satoru; Kusano Motoyasu; Yamada Masanobu, Dec. 2015, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30, 377, 378
  • Malignant peripheral nerve sheath tumor of the liver, Horiguchi Norio; Kakizaki Satoru; Otsuka Toshiyuki; Takizawa Daichi; Yamazaki Yuichi; Sato Ken; Ohno Yoshihiro; Kusano Motoyasu; Yamada Masanobu, Dec. 2015, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30, 331
  • A case of endoscopic treatment for esophageal varices complicated by Isaacs' syndrome involving difficulty with conventional sedation, Suzuki Yuhei; Yamazaki Yuichi; Hashizume Hiroaki; Ohyama Tatsuya; Horiguchi Norio; Sato Ken; Kakizaki Satoru; Kusano Motoyasu; Yamada Masanobu, Dec. 2015, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30, 308, 308
  • 肝表および横隔膜下の肝細胞癌に対し経皮的凍結療法を施行した1例, 宮崎 将也; 渡邊 義也; 熊坂 創真; 徳江 浩之; 大山 達也; 山崎 勇一; 堀口 昇男; 佐藤 賢; 柿崎 暁; 山田 正信; 対馬 義人, Nov. 2014, 3, Suppl.2, 62, 62
  • マウスアルコール性脂肪性肝炎モデルにおける細胞特異的なSTAT3の役割, 堀口 昇男; 柿崎 暁; 橋爪 洋明; 山崎 勇一; 佐藤 賢; 森 昌朋; Gao Bin, Jan. 2014, アルコールと医学生物学, 32, 9-11., 11
  • Genotype 2かつ高ウイルス量C型慢性肝炎に対するResponse-Guided Therapy, 佐藤 賢; 橋爪 洋明; 山崎 勇一; 堀口 昇男; 柿崎 暁; 高木 均; 森 昌朋, 2012
  • 減量手術が必要な高度肥満患者の肝臓病変, 柿崎 暁; 関 洋介; 橋爪 洋明; 山崎 勇一; 笠間 和典; 森 昌朋, 2012, 54, 6, 699, 704
  • A case of hemorr.hagic gastroduodenitis after proton beam radiation for pancreatic cancer with multiple hemorrhagic risk factors: successful treatment with argon plasma coagulation., Hashizume H; Sato K; Horiguchi N; Yamazaki Y; Kakizaki S; Sakurai H; Mori M, 2012, Clin J Gastroenterol, 5, 5, 336, 340, Scientific journal
  • The status and problems in subsidizing interferon treatment in Gunma prefecture, KAKIZAKI Satoru; YAMAZAKI Yuichi; HASHIZUME Hiroaki; HORIGUCHI Norio; SATO Ken; MORI Masatomo; ABE Takehiko; TAKAGI Hitoshi; SATO Tomoko; YOKOI Toshiyuki; KAWASAKI Hidehiro; KOBAYASHI Jiro; NAGAMINE Takeaki, 25 May 2011, Kanzo, 52, 5, 287, 294, Scientific journal
  • Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis, Daichi Takizawa; Satoru Kakizaki; Norio Horiguchi; Yuichi Yamazaki; Hiroki Tojima; Masatomo Mori, Apr. 2011, CARCINOGENESIS, 32, 4, 576, 583, Scientific journal
  • Transforming growth factor-alpha attenuates hepatic fibrosis: possible involvement of matrix metalloproteinase-1, Ohyama Tatsuya; Yamazaki Yuichi; Sato Ken; Horiguchi Norio; Ichikawa Takeshi; Kakizaki Satoru; Takagi Hitoshi; Mori Masatomo, Apr. 2011, LIVER INTERNATIONAL, 31, 4, 572, 584, Scientific journal
  • 減量手術が必要な高度肥満患者における生活習慣病, 柿崎 暁; 大学院医学系研究科病態制御内科学; 関 洋介; 橋爪 洋明; 山崎 勇一; 森 昌朋; 笠間 和典, 2011
  • Nonalcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) in comparison to non-Japanese patients, Satoru Kakizaki; Daichi Takizawai; Yuichi Yamazaki; Yuka Nakajima; Takeshi Ichikawa; Ken Sato; Hitoshi Takagi; Masatomo Mori; Kazunori Kasama, 2008, JOURNAL OF GASTROENTEROLOGY, 43, 1, 86, 92, Scientific journal
  • Erratum: (Liver International), Satoru Kakizaki; Yuichi Yamazaki; Takashi Kosone; Norio Horigichi; Naondo Sohara; Ken Sato; Hitoshi Takagi; Kouichi Yoshinari; Masatomo Mori, 01 Jun. 2007, Liver International, 27, 733
  • 経皮的肝生検術における予防的抗菌療法, 柿崎 暁; 蘇原 直人; 佐藤 賢; 湯浅 和久; 山崎 勇一; 小曽根 隆; 高木 均; 森 昌朋, Apr. 2004, 肝臓, 45, 4, 186, 191
  • An autopsy case of intrahepatic cholangiocarcinoma resembling amebic liver abscess, YAMAZAKI Yuichi; KUWABARA Hidemasa; KAKIZAKI Satoru; TAKAYAMA Hisashi; TAKAGI Hitoshi; MORI Masatomo; YAMAUCHI Hideo; NAGAMINE Takeaki, Apr. 2003, Kanzo, 44, 4, 145, 149
  • 肝硬変患者に対する分岐鎖アミノ酸顆粒臨床試験, 中島 弘明; 高橋 仁公; 山崎 勇一; 市川 武; 下田 隆也; 小島 明; 小曽根 隆; 神田 大輔; 多胡 洋子; 柿崎 暁; 高山 尚; 高木 均; 長嶺 竹明; 森 昌朋, May 2000, JJPEN: The Japanese Journal of Parenteral and Enteral Nutrition, 22, 5, 353, 360
  • Adolescents with chronic hepatitis C might be good candidates for direct-acting antiviral therapy., Ken Sato; Yuichi Yamazaki; Yuki Kanayama; Daisuke Uehara; Hiroki Tojima; Takayoshi Suga; Satoru Kakizaki; Naondo Sohara; Norio Horiguchi; Toshio Uraoka, Apr. 2022, Clinical case reports, 10, 4, e05690
  • [Liver injury in patients with moderate II COVID-19 who received dexamethasone monotherapy]., Yuichi Yamazaki; Yuki Kanayama; Daisuke Uehara; Takayoshi Suga; Hirohito Tanaka; Hiroki Tojima; Shiko Kuribayashi; Ken Sato; Satoru Kakizaki; Toshio Uraoka, 2022, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 119, 4, 332, 341, Scientific journal
  • Strategy for the control of drug-induced liver injury due to investigational treatments/drugs for COVID-19., Ken Sato; Yuichi Yamazaki; Toshio Uraoka, 28 Dec. 2021, World journal of gastroenterology, 27, 48, 8370, 8373, Scientific journal
  • Chronic Infection with Hepatitis C Virus Subtype 1 g in a Japanese Patient Successfully Treated with Glecaprevir/Pibrentasvir., Takeshi Hatanaka; Satoru Kakizaki; Takuya Kaburagi; Naoto Saito; Sachi Nakano; Yoichi Hazama; Sachiko Yoshida; Yoko Hachisu; Yoshiki Tanaka; Teruo Yoshinaga; Kenji Kashiwabara; Atsushi Naganuma; Yuichi Yamazaki; Toshio Uraoka; Shigeo Nagashima; Masaharu Takahashi; Tsutomu Nishizawa; Kazumoto Murata; Hiroaki Okamoto, 11 Dec. 2021, Internal medicine (Tokyo, Japan), 61, 10, 1537, 1543, Scientific journal
  • Successful treatment of Japanese hemophilia patient co-infected with HIV and HCV genotype 4a by glecaprevir/pibrentasvir therapy., Ken Sato; Yuki Kanayama; Yuichi Yamazaki; Hiroki Tojima; Takayoshi Suga; Daisuke Uehara; Satoru Kakizaki; Kunio Yanagisawa; Toshio Uraoka; Hiroshi Ohnishi; Hiroaki Okamoto, Dec. 2021, Clinical journal of gastroenterology, 14, 6, 1725, 1732, Scientific journal
  • An Autopsy Case of Multicentric Castleman Disease Presenting with Severe Jaundice., Yuichi Yamazaki; Yuka Yoshida; Megumi Shimizu; Takeshi Kobayashi; Hiroki Tojima; Ken Sato; Satoru Kakizaki; Hiroshi Handa; Hideaki Yokoo; Toshio Uraoka, 15 Nov. 2021, Internal medicine (Tokyo, Japan), 60, 22, 3615, 3620, Scientific journal
  • The first reported case of Noonan syndrome complicated with hepatocellular carcinoma., Satoru Kakizaki; Daisuke Uehara; Hiroki Tojima; Takayoshi Suga; Yuichi Yamazaki; Ken Sato; Norio Kubo; Ken Shirabe; Takayuki Yokota; Kei Shibuya; Tatsurou Maehara; Hideaki Yokoo; Atsushi Naganuma; Toshio Uraoka, Jul. 2021, Clinical case reports, 9, 7, e04317
  • Correlative microscopy and block-face imaging (CoMBI) method for both paraffin-embedded and frozen specimens., Nobukazu Ishii; Yuki Tajika; Tohru Murakami; Josephine Galipon; Hiroyoshi Shirahata; Ryo Mukai; Daisuke Uehara; Ryosuke Kaneko; Yuichi Yamazaki; Yuhei Yoshimoto; Hirohide Iwasaki, 23 Jun. 2021, Scientific reports, 11, 1, 13108, 13108, Scientific journal
  • 当科における新規ガイドワイヤRevoWave SeekMasterの使用経験, 善如寺 暖; 清水 雄大; 阿部 貴紘; 石田 克敏; 佐藤 圭吾; 關谷 真志; 橋本 悠; 植原 大介; 須賀 孝慶; 田中 寛人; 戸島 洋貴; 保坂 浩子; 栗林 志行; 山崎 勇一; 下山 康之; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, Oct. 2020, 62, Suppl.2, 2135, 2135
  • Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review., Hidekazu Ikeuchi; Kana Koinuma; Masao Nakasatomi; Toru Sakairi; Yoriaki Kaneko; Akito Maeshima; Yuichi Yamazaki; Hiroaki Okamoto; Toshihide Mimura; Satoshi Mochida; Yoshihisa Nojima; Keiju Hiromura, 2018, Case reports in rheumatology, 2018, 6873276, 6873276
  • Drug-induced liver injury caused by a dietary supplement (Kin-toki Shoga®) made from ginger, Yuhei Suzuki; Yuichi Yamazaki; Hiroaki Hashizume; Tatsuya Oyama; Norio Horiguchi; Ken Sato; Satoru Kakizaki; Masanobu Yamada, 01 Jan. 2015, Journal of Japanese Society of Gastroenterology, 112, 1, 108, 114, Scientific journal
  • Sofosbuvir/Ribavirin therapy for patients experiencing failure of ombitasvir/paritaprevir/ritonavir plus ribavirin therapy: Two cases report and review of literature, Sato, Ken;Yamazaki, Yuichi;Kobayashi, Takeshi;Takakusagi, Satoshi;Horiguchi, Norio;Kakizaki, Satoru;Andou, Masayasu;Matsuda, Yoshihiro;Uraoka, Toshio;Ohnishi, Hiroshi;Okamoto, Hiroaki, 2019, WORLD JOURNAL OF CLINICAL CASES, 7, 9, 1043, 1052
  • Long-term Results of Bariatric Surgery for Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis Treatment in Morbidly Obese Japanese Patients, Uehara, Daisuke;Seki, Yosuke;Kakizaki, Satoru;Horiguchi, Norio;Tojima, Hiroki;Yamazaki, Yuichi;Sato, Ken;Yamada, Masanobu;Uraoka, Toshio;Kasama, Kazunori, 2019, OBESITY SURGERY, 29, 4, 1195, 1201
  • Correlative microscopy and block-face imaging (CoMBI) method for both paraffin-embedded and frozen specimens, Ishii, Nobukazu;Tajika, Yuki;Murakami, Tohru;Galipon, Josephine;Shirahata, Hiroyoshi;Mukai, Ryo;Uehara, Daisuke;Kaneko, Ryosuke;Yamazaki, Yuichi;Yoshimoto, Yuhei;Iwasaki, Hirohide, 2021, SCIENTIFIC REPORTS, 11, 1
  • Characteristics of cases of hepatitis E in Gunma prefecture: Small epidemics caused by the same subgenotype 3a strains, Yamazaki, Yuichi;Ueno, Takashi;Hatanaka, Takeshi;Takakusagi, Satoshi;Takizawa, Daichi;Naganuma, Atsushi;Kosone, Takashi;Nakajima, Hiroaki;Sato, Ken;Kakizaki, Satoru;Takagi, Hitoshi;Uraoka, Toshio;Takahashi, Masaharu;Nagashima, Shigeo;Okamoto, Hiroaki, 2021, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 36, 87, 88
  • ERCP with a rotary papillotome was facilitated by adjusting monitor position in a patient with situs inversus totalis, Zennyoji, Dan;Sato, Ken;Sato, Keigo;Abe, Takahiro;Sekiya, Masashi;Hashimoto, Yu;Uehara, Daisuke;Shimizu, Takehiro;Suga, Takayoshi;Hosaka, Hiroko;Tanaka, Hirohito;Tojima, Hiroki;Kuribayashi, Shiko;Yamazaki, Yuichi;Uraoka, Toshio, 2021, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 36, 88, 89
  • Strategy for the control of drug-induced liver injury due to investigational treatments/drugs for COVID-19, Sato, Ken;Yamazaki, Yuichi;Uraoka, Toshio, 2021, WORLD JOURNAL OF GASTROENTEROLOGY, 27, 48, 8370, 8373
  • Chronic Infection with Hepatitis C Virus Subtype 1g in a Japanese Patient Successfully Treated with Glecaprevir/Pibrentasvir, Hatanaka, Takeshi;Kakizaki, Satoru;Kaburagi, Takuya;Saito, Naoto;Nakano, Sachi;Hazama, Yoichi;Yoshida, Sachiko;Hachisu, Yoko;Tanaka, Yoshiki;Yoshinaga, Teruo;Kashiwabara, Kenji;Naganuma, Atsushi;Yamazaki, Yuichi;Uraoka, Toshio;Nagashima, Shigeo;Takahashi, Masaharu;Nishizawa, Tsutomu;Murata, Kazumoto;Okamoto, Hiroaki, 2022, INTERNAL MEDICINE, 61, 10, 1537, 1543
  • A retrospective analysis of pembrolizumab in patients with high microsatellite instability cholangiocarcinoma, Shimizu, Takehiro;Naganuma, Atsushi;Matsui, Ayako;Murakami, Tatsuma;Kanamaya, Yuuki;Zennyoji, Dan;Suga, Takayoshi;Tojima, Hiroki;Yamazaki, Yuichi;Kakizaki, Satoru;Sato, Ken;Uraoka, Toshio, 2022, ANNALS OF ONCOLOGY, 33, S518, S518
  • An Autopsy Case of Multicentric Castleman Disease Presenting with Severe Jaundice, Yamazaki Yuichi;Yoshida Yuka;Shimizu Megumi;Kobayashi Takeshi;Tojima Hiroki;Sato Ken;Kakizaki Satoru;Handa Hiroshi;Yokoo Hideaki;Uraoka Toshio, 2021, Internal Medicine, advpub, 0, 3615, 3620
  • Chronic Infection with Hepatitis C Virus Subtype 1g in a Japanese Patient Successfully Treated with Glecaprevir/Pibrentasvir, Hatanaka Takeshi;Kakizaki Satoru;Kaburagi Takuya;Saito Naoto;Nakano Sachi;Hazama Yoichi;Yoshida Sachiko;Hachisu Yoko;Tanaka Yoshiki;Yoshinaga Teruo;Kashiwabara Kenji;Naganuma Atsushi;Yamazaki Yuichi;Uraoka Toshio;Nagashima Shigeo;Takahashi Masaharu;Nishizawa Tsutomu;Murata Kazumoto;Okamoto Hiroaki, May 2022, Internal Medicine, 61, 10, 1537, 1543
  • Hepatocellular carcinoma in extremely elderly patients: an analysis of clinical characteristics, prognosis and patient survival., Tsukioka Gengo;Kakizaki Satoru;Sohara Naondo;Sato Ken;Takagi Hitoshi;Arai Hirotaka;Abe Takehiko;Toyoda Mitsuo;Katakai Kenji;Kojima Akira;Yamazaki Yuichi;Otsuka Toshiyuki;Matsuzaki Yutaka;Makita Fujio;Kanda Daisuke;Horiuchi Katsuhiko;Hamada Tetsuya;Kaneko Mieko;Suzuki Hideyuki;Mori Masatomo, World journal of gastroenterology, 12, 1
  • NS5A-P29欠損を有し、複数のDAA治療に抵抗性を示したが、ソホスブビル/ベルパタスビル/リバビリン併用療法が著効したC型慢性肝炎の1例, ;;;;;;;;, Nov. 2020, 61, Suppl.3, A881
  • 多発肺転移にレンバチニブが奏功し、休薬後に腹腔内出血を生じた肝細胞癌の一剖検例, ;;;;;;;, Nov. 2020, 61, Suppl.3, A894
  • 当院におけるCOVID-19患者の肝障害についての検討, ;;;;;;;, Jun. 2021, 62, 6, 381
  • 背景軽度線維化例におけるNBNC肝癌の特徴, ;;;;;;;;;;, Sep. 2021, 62, Suppl.2, A562
  • 内視鏡的逆行性膵胆管造影における0.030inchガイドワイヤと0.025inchガイドワイヤの比較, ;;;;;;;;;;;;;;, Apr. 2021, 63, Suppl.1, 889
  • デキサメタゾン単独療法を行ったCOVID-19中等症II患者の肝障害についての検討, ;;;;;;;;;, Apr. 2022, 119, 4, 332
  • 高度肥満患者における新規バイオマーカーの探索, ;;;;, Aug. 2021, 71, 3, 264
  • [Case report: a case of IgG4-associated autoimmune pancreatitis accompanying liver inflammatory pseudotumor]., Iizuka Takashi;Shibusawa Nobuyuki;Yoshida Sachiko;Mizuide Masafumi;Ono Akihiro;Yamazaki Yuichi;Takahashi Hiroki;Satoh Tetsurou;Kusano Motoyasu;Mori Masatomo, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 101, 2
  • An Autopsy Case of Fulminant Hepatitis in a Patient with Multiple Sclerosis Treated by Interferon-Beta-1a., Yamazaki Yuichi;Suzuki Aya;Hirayanagi Kimitoshi;Tsukagoshi Yusuke;Uehara Ryota;Horiguchi Kazuhiko;Ohyama Tatsuya;Tomaru Takuya;Horiguchi Norio;Nobusawa Sumihito;Ikota Hayato;Sato Ken;Kakizaki Satoru;Kusano Motoyasu;Ikeda Yoshio;Yokoo Hideaki;Yamada Masanobu, 15 Jul. 2017, Internal medicine (Tokyo, Japan), 56, 14
  • An Autopsy Case of Multicentric Castleman Disease Presenting with Severe Jaundice., Yamazaki Yuichi;Yoshida Yuka;Shimizu Megumi;Kobayashi Takeshi;Tojima Hiroki;Sato Ken;Kakizaki Satoru;Handa Hiroshi;Yokoo Hideaki;Uraoka Toshio, 05 Jun. 2021, Internal medicine (Tokyo, Japan), 60, 22
  • The first reported case of Noonan syndrome complicated with hepatocellular carcinoma., Kakizaki Satoru;Uehara Daisuke;Tojima Hiroki;Suga Takayoshi;Yamazaki Yuichi;Sato Ken;Kubo Norio;Shirabe Ken;Yokota Takayuki;Shibuya Kei;Maehara Tatsurou;Yokoo Hideaki;Naganuma Atsushi;Uraoka Toshio, 09 Jul. 2021, Clinical case reports, 9, 7
  • 全科協力体制下でのCOVID-19診療における内科医かつ消化器内科医の役割, ;;, Oct. 2021, 118, 臨増大会, A681
  • デキサメタゾン単独療法を行ったCOVID-19中等症II患者の肝障害についての検討, ;;;;;;;;;, Apr. 2022, 119, 4, 332
  • ERCP下胆道生検におけるEndotheaserの有用性, ;;;;;;;;;, Apr. 2022, 64, Suppl.1, 818
  • Chronic hepatitis E in an elderly immunocompetent patient who achieved a sustained virologic response with ribavirin treatment., Satoshi Takakusagi; Hitoshi Takagi; Yuichi Yamazaki; Takashi Kosone; Shigeo Nagashima; Masaharu Takahashi; Kazumoto Murata; Hiroaki Okamoto, Apr. 2023, Clinical journal of gastroenterology, 16, 2, 206, 215, Scientific journal
  • 減量手術が必要な高度肥満患者の肝臓病変, 柿崎 暁; 関 洋介; 橋爪 洋明; 山崎 勇一; 笠間 和典; 森 昌朋, Jul. 2013, 未病と抗老化, 22, 105, 109
  • A case of IgG4-associated autoimmune pancreatitis accompanying liver inflammatory pseudotumor, IIZUKA Takashi; SHIBUSAWA Nobuyuki; YOSHIDA Sachiko; MIZUIDE Masafumi; ONO Akihiro; YAMAZAKI Yuichi; TAKAHASHI Hiroki; SATOH Tetsurou; KUSANO Motoyasu; MORI Masatomo, 10 Feb. 2012, Nihon Naika Gakkai Kaishi, 101, 2, 468, 471
  • A Case of Metabolic Acidosis with Hyperchloremia Induced by Prolonged Intravenous Administration of Branched Chain Amino Acid Enriched Solution for Hepatic Encephalopathy., Shimoda Ryuya; Abe Takehiko; Arai Hirotaka; Kosone Takashi; Hagiwara Satoshi; Onozato Yasuhiro; Ishihara Hiroshi; Itoh Hideaki; Iwasaki Yasuki; Nara Mami; Tsukioka Gengo; Suzuki Hideyuki; Yamazaki Yuichi; Ichikawa Takeshi; Takagi Hitoshi; Nagamine Takeaki; Mori Masatomo, 2000, The KITAKANTO Medical Journal, 50, 6, 535, 541
  • Characteristics of liver injury in cases of COVID-19, Yuichi Yamazaki; Daisuke Uehara; Yuki Kanayama; Takayoshi Suga; Hiroki Tojima; Ken Sato; Satoru Kakizaki; Toshio Uraoka, 01 Jun. 2021, Acta Hepatologica Japonica, 62, 6, 381, 383, Scientific journal
  • Tolvaptan reduces the required amount of albumin infusion in patients with decompensated cirrhosis with uncontrolled ascites: A multicenter retrospective propensity score-matched cohort study, Y. Suzuki; A. Naganuma; T. Hoshino; T. Hatanaka; T. Ueno; M. Namikawa; D. Takizawa; H. Arai; H. Suzuki; H. Takagi; H. Tojima; Y. Yamazaki; K. Sato; S. Kakizaki; T. Uraoka, 2021, Acta Gastro-Enterologica Belgica, 84, 1, 57, 63, Scientific journal
  • ヒト胆管細胞癌株におけるgefitinib・gemcitabine併用療法の有用性に関する検討, 中島 良実; 高木 均; 柿崎 暁; 堀口 昇男; 佐藤 賢; 山崎 勇一; 森 昌朋, Apr. 2013, 肝臓, 54, Suppl.1, A136, A136
  • Partial liver irradiation in rats induces the hypertrophy of nonirradiated liver lobes through hepatocyte proliferation†., Takuya Adachi; Yukari Yoshida; Kei Shibuya; Ken Sato; Yuichi Yamazaki; Satoru Kakizaki; Toshio Uraoka; Akihisa Takahashi, 18 Jul. 2023, Journal of radiation research, 64, 4, 693, 701, Scientific journal
  • A Newly Developed Method-Based Xanthine Oxidoreductase Activities in Various Human Liver Diseases., Ken Sato; Atsushi Naganuma; Tamon Nagashima; Yosuke Arai; Yuka Mikami; Yuka Nakajima; Yuki Kanayama; Tatsuma Murakami; Sanae Uehara; Daisuke Uehara; Yuichi Yamazaki; Takayo Murase; Takashi Nakamura; Toshio Uraoka, 14 May 2023, Biomedicines, 11, 5, Scientific journal
  • Association Between Liver Injury and Pneumonia in Patients Hospitalized with COVID-19, -With a Focus on Pregnant Women, Tatsuma Murakami; Yuichi Yamazaki; Yumeo Tateyama; Yuki Kanayama; Daisuke Uehara; Takayoshi Suga; Hiroki Tojima; Ken Sato; Satoru Kakizaki; Toshio Uraoka, 01 Mar. 2025, Kanzo, 66, 3, 71, 77, Scientific journal
  • Evaluation of the Efficacy of Lusutrombopag for Chronic Liver Disease Based on Pre-Treatment Platelet Counts: A Retrospective Multicenter Study., Takayoshi Suga; Satoru Kakizaki; Atsushi Naganuma; Takeshi Hatanaka; Satoshi Takakusagi; Daichi Takizawa; Hirotaka Arai; Takashi Ueno; Keisuke Iizuka; Toru Fukuchi; Shuichi Saito; Hiroki Tojima; Yuichi Yamazaki; Toshio Uraoka, Jan. 2025, JGH open : an open access journal of gastroenterology and hepatology, 9, 1, e70081, Scientific journal
  • 投与前血小板値からみたルストロンボパグの有効性の検討-多施設共同研究, 須賀 孝慶; 柿崎 暁; 長沼 篤; 畑中 健; 高草木 智史; 滝澤 大地; 新井 弘隆; 上野 敬史; 飯塚 圭介; 福地 達; 齋藤 秀一; 戸島 洋貴; 山崎 勇一; 浦岡 俊夫, Sep. 2024, 65, Suppl.2, A683, A683
  • 胃と吻合部の静脈瘤破裂に対するRed Dichromatic Imaging(RDI)の使用経験, 村上 立真; 山崎 勇一; 金山 雄樹; 戸島 洋貴; 浦岡 俊夫, Jun. 2024, 105, Suppl., s90, s90
  • 肝細胞癌のリンパ節転移に対し,アテゾリズマブ/ベバシズマブ療法によりCRとなり,conversion治療が可能となった1例, 本多 夏穂; 佐藤 賢; 清水 雄大; 渡辺 亮; 金山 雄樹; 村上 立真; 清水 創一郎; 戸島 洋貴; 山崎 勇一; 播本 憲史; 調 憲; 浦岡 俊夫, Apr. 2024, 65, Suppl.1, A301, A301
  • 肝硬変症例における代謝異常を伴うアルコール性肝障害とMASLD/MetALDの比較検討, 戸島 洋貴; 柿崎 暁; 長沼 篤; 上野 敬史; 飯塚 圭介; 畑中 健; 須賀 孝慶; 齋藤 秀一; 福地 達; 滝澤 大地; 新井 弘隆; 山崎 勇一; 佐藤 賢; 浦岡 俊夫, Apr. 2024, 65, Suppl.1, A427, A427
  • レンバチニブとTACEにより長期制御が可能であった多発肝細胞癌の一例, 冨澤 佳那子; 山崎 勇一; 村上 立真; 金山 雄樹; 戸島 洋貴; 浦岡 俊夫, Feb. 2024, 378回, 35, 35
  • 肝外門脈閉塞症に伴う求肝性の静脈瘤破裂に対して経皮経肝的静脈瘤塞栓術(PTO)と門脈ステント留置術を行った2例, Aung Paing Moe; 村上 立真; 清水 創一郎; 金山 雄樹; 戸島 洋貴; 山崎 勇一; 佐藤 賢; 浦岡 俊夫, Oct. 2023, 64, Suppl.3, A912, A912
  • 肝細胞癌に対する定位放射線治療の有効性と安全性, 柴崎 充彦; 新井 弘隆; 舘山 夢生; 滝澤 大地; 甲賀 達也; 飯塚 圭介; 上野 敬史; 高草木 智史; 高木 均; 金山 雄樹; 戸島 洋貴; 山崎 勇一; 浦岡 俊夫, Sep. 2023, 64, Suppl.2, A627, A627
  • 当院における急性肝不全症例の臨床的検討, 田村 優樹; 山崎 勇一; 清水 創一郎; 村上 立真; 金山 雄樹; 戸島 洋貴; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, Sep. 2023, 64, Suppl.2, A643, A643
  • 肝細胞癌のカテーテル治療による肝予備能変化と寄与する因子の検討, 滝澤 大地; 新井 弘隆; 柴崎 充彦; 舘山 夢生; 戸島 洋貴; 金山 雄樹; 山崎 勇一; 浦岡 俊夫, Sep. 2023, 64, Suppl.2, A645, A645
  • 無菌性膿瘍症候群を伴う潰瘍性大腸炎にJAK阻害薬が著効した一例, 星野 駿介; 橋本 悠; 喜多 碧; 都丸 翔太; 糸井 祐貴; 佐藤 圭吾; 村上 立真; 金山 雄樹; 善如寺 暖; 清水 雄大; 保坂 浩子; 田中 寛人; 戸島 洋貴; 栗林 志行; 山崎 勇一; 竹内 洋司; 浦岡 俊夫, Sep. 2023, 376回, 49, 49
  • 悪性症候群を合併した特発性急性膵炎の1例, 井戸 健太; 善如寺 暖; 喜多 碧; 都丸 翔太; 糸井 祐貴; 佐藤 圭吾; 村上 立真; 橋本 悠; 金山 雄樹; 清水 雄大; 保坂 浩子; 田中 寛人; 戸島 洋貴; 栗林 志行; 山崎 勇一; 竹内 洋司; 浦岡 俊夫, Jul. 2023, 375回, 38, 38
  • 当院におけるアルコール関連疾患及び肝疾患の現状, 山崎 勇一; 清水 創一郎; 村上 立真; 金山 雄樹; 戸島 洋貴; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, Mar. 2023, 120, 臨増総会, A399, A399
  • 慢性肉芽腫症患者に発症した難治性肝膿瘍の1例, Paingmoe Aung; 金山 雄樹; 清水 創一郎; 村上 立真; 戸島 洋貴; 栗林 志行; 山崎 勇一; 佐藤 賢; 浦岡 俊夫, Dec. 2022, 683回, 30, 30
  • TACEや栄養状態が肝細胞癌の多発肺転移の縮小に影響したと考えられる一例, 佐藤 賢; 植原 大介; 山崎 勇一; 戸島 洋貴; 村上 立真; 清水 創一郎; 金山 雄樹; 浦岡 俊夫, Oct. 2022, 63, Suppl.3, A774, A774
  • 胃全摘術後の食道空腸吻合部静脈瘤破裂に対して内視鏡バルーン補助下での経皮経肝静脈瘤塞栓術(PTO)が奏功した一例, 清水 創一郎; 金山 雄樹; 須賀 考慶; 戸島 洋貴; 山崎 勇一; 佐藤 賢; 浦岡 俊夫, Oct. 2022, 63, Suppl.3, A839, A839
  • COVID-19妊婦の肝障害についての検討, 山崎 勇一; 村上 立真; 金山 雄樹; 植原 大介; 須賀 孝慶; 戸島 洋貴; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, Sep. 2022, 63, Suppl.2, A559, A559
  • グレカプレビル水和物・ピブレンタスビル配合剤治療中に妊娠が判明し3週間内服で持続的ウイルス学的著効を達成したC型肝炎の一例, 丸山 優; 山崎 勇一; 村上 立真; 金山 雄樹; 須賀 孝慶; 戸島 洋貴; 佐藤 賢; 羽鳥 麗子; 石毛 崇; 浦岡 俊夫, May 2022, 369回, 48, 48
  • ERCP下胆道生検におけるEndotheaserの有用性, 村上 立真; 清水 雄大; 浦岡 俊夫; 阿部 貴紘; 善如寺 暖; 佐藤 賢; 金山 雄樹; 須賀 孝慶; 戸島 洋貴; 山崎 勇一, Apr. 2022, 64, Suppl.1, 818, 818
  • ゲフィチニブ治療後にFDG集積の低下を認めた原発性肺腺癌甲状腺転移の1例, 須賀 孝慶; 山崎 勇一; 上出 庸介; 登丸 琢也; 岩崎 靖樹; 砂長 則明; 山田 正信; 森 昌朋, Dec. 2012, 593回, 30, 30
  • Immune thrombocytopenic purpura in patients with hepatitis C virus infection, Hiroaki Nakajima; Hitoshi Takagi; Yuichi Yamazaki; Mitsuo Toyoda; Jirou Takezawa; Takeaki Nagamine; Masatomo Mori, Jul. 2005, Hepato-Gastroenterology, 52, 64, 1197, 1200, Scientific journal

MISC

  • Hepatology - Elevated plasma resistin concentrations in patients with liver cirrhosis, Satoru Kakizaki; Naondo Sohara; Yuichi Yamazaki; Norio Horiguchi; Daisuke Kanda; Kenji Kabeya; Kenji Katakai; Ken Sato; Hitoshi Takagi; Masatomo Mori, Jan. 2008, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23, 1, 73, 77
  • Interstrain differences in susceptibility to non-alcoholic steatohepatitis, Yuichi Yamazaki; Satoru Kakizaki; Daichi Takizawa; Takeshi Ichikawa; Ken Sato; Hitoshi Takagi; Masatomo Mori, Feb. 2008, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23, 2, 276, 282
  • Overexpression of NK2 promotes liver fibrosis in carbon tetrachloride-induced chronic liver injury, Satoshi Hagiwara; Toshiyuki Otsuka; Yuichi Yamazaki; Takashi Kosone; Naondo Sohara; Takeshi Ichikawa; Ken Sato; Satoru Kakizaki; Hitoshi Takagi; Masatomo Mori, Jan. 2008, LIVER INTERNATIONAL, 28, 1, 126, 131
  • Full Genome Analysis of a European-Type Genotype 3 Hepatitis E Virus Variant Obtained From a Japanese Patient With Autochthonous Acute Hepatitis E, Suguru Takeuchi; Yuichi Yamazaki; Ken Sato; Daichi Takizawa; Masanobu Yamada; Hiroaki Okamoto, Jul. 2015, JOURNAL OF MEDICAL VIROLOGY, 87, 7, 1067, 1071
  • Expression of amino acid transporters (LAT1, ASCT2 and xCT) as clinical significance in hepatocellular carcinoma, Masashi Namikawa; Satoru Kakizaki; Kyoichi Kaira; Hiroki Tojima; Yuichi Yamazaki; Norio Horiguchi; Ken Sato; Noboru Oriuchi; Hideyuki Tominaga; Yutaka Sunose; Shushi Nagamori; Yoshikatsu Kanai; Tetsunari Oyama; Izumi Takeyoshi; Masanobu Yamada, Sep. 2015, HEPATOLOGY RESEARCH, 45, 9, 1014, 1022
  • Pregnane X Receptor Represses HNF4 alpha Gene to Induce Insulin-Like Growth Factor-Binding Protein IGFBP1 that Alters Morphology of and Migrates HepG2 Cells, Susumu Kodama; Yuichi Yamazaki; Masahiko Negishi, Oct. 2015, MOLECULAR PHARMACOLOGY, 88, 4, 746, 757
  • Hepatic Angiosarcoma with Dyskeratosis Congenita, Norio Horiguchi; Satoru Kakizaki; Keisuke Iizuka; Satoshi Hagiwara; Tatsuya Ohyama; Yuichi Yamazaki; Nobuyuki Shibusawa; Ken Sato; Motoyasu Kusano; Yoichi Nakazato; Masanobu Yamada, 2015, INTERNAL MEDICINE, 54, 22, 2867, 2872
  • Probable case of drug reaction with eosinophilia and systemic symptom syndrome due to combination therapy with daclatasvir and asunaprevir, Takayoshi Suga; Ken Sato; Yuichi Yamazaki; Tatsuya Ohyama; Norio Horiguchi; Satoru Kakizaki; Motoyasu Kusano; Masanobu Yamada, Dec. 2015, WORLD JOURNAL OF CLINICAL CASES, 3, 12, 1005, 1010
  • A Prospective Randomized Controlled Study of Long-Term Combination Therapy Using Ursodeoxycholic Acid and Bezafibrate in Patients With Primary Biliary Cirrhosis and Dyslipidemia, Kenichi Hosonuma; Ken Sato; Yuichi Yamazaki; Masatoshi Yanagisawa; Hiroaki Hashizume; Norio Horiguchi; Satoru Kakizaki; Motoyasu Kusano; Masanobu Yamada, Mar. 2015, AMERICAN JOURNAL OF GASTROENTEROLOGY, 110, 3, 423, 431
  • Interferon treatment for patients with chronic hepatitis C complicated with chronic renal failure receiving hemodialysis, Akira Kojima; Satoru Kakizaki; Ken-ichi Hosonuma; Yuichi Yamazaki; Norio Horiguchi; Ken Sato; Tokuyuki Kitahara; Masatomo Mori, Apr. 2013, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28, 4, 690, 699
  • Extended therapy duration for therapy-refractory hepatitis C patients with genotype 2, Ken Sato; Masatoshi Yanagisawa; Hiroaki Hashizume; Yuichi Yamazaki; Norio Horiguchi; Satoru Kakizaki; Masatomo Mori, Sep. 2013, WORLD JOURNAL OF GASTROENTEROLOGY, 19, 34, 5754, 5758
  • Transforming growth factor-alpha activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation, Hiroki Tahara; Ken Sato; Yuichi Yamazaki; Tatsuya Ohyama; Norio Horiguchi; Hiroaki Hashizume; Satoru Kakizaki; Hitoshi Takagi; Iwata Ozaki; Hideo Arai; Junko Hirato; Ralf Jesenofsky; Atsushi Masamune; Masatomo Mori, Jun. 2013, LABORATORY INVESTIGATION, 93, 6, 720, 732
  • A Prospective Study of Long-term Outcomes in Female Patients with Nonalcoholic Steatohepatitis Using Age- and Body Mass Index-matched Cohorts, Hiroaki Hashizume; Ken Sato; Yuichi Yamazaki; Norio Horiguchi; Satoru Kakizaki; Masatomo Mori, Feb. 2013, ACTA MEDICA OKAYAMA, 67, 1, 45, 53
  • Histone Deacetylase Inhibitors Induce Cytochrome P450 2B by Activating Nuclear Receptor Constitutive Androstane Receptor, Daichi Takizawa; Satoru Kakizaki; Norio Horiguchi; Hiroki Tojima; Yuichi Yamazaki; Takeshi Ichikawa; Ken Sato; Masatomo Mori, Sep. 2010, DRUG METABOLISM AND DISPOSITION, 38, 9, 1493, 1498
  • The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis., Yuichi Yamazaki; Satoru Kakizaki; Norio Horiguchi; Naondo Sohara; Ken Sato; Hitoshi Takagi; Masatomo Mori; Masahiko Negishi, Apr. 2007, Gut, 56, 4, 565, 74
  • The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis, Yuichi Yamazaki; Satoru Kakizaki; Norio Horiguchi; Naondo Sohara; Ken Sato; Hitoshi Takagi; Masatomo Mori; Masahiko Negishi, Apr. 2007, GUT, 56, 4, 565, 574
  • Hepatocellular carcinoma in young adults: The clinical characteristics, prognosis, and findings of a patient survival analysis, Yuichi Yamazaki; Satoru Kakizaki; Naondo Sohara; Ken Sato; Hitoshi Takagi; Hirotaka Arai; Takehiko Abe; Kenji Katakai; Akira Kojima; Yutaka Matsuzaki; Masatomo Mori, Apr. 2007, DIGESTIVE DISEASES AND SCIENCES, 52, 4, 1103, 1107
  • Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor, Satoru Kakizaki; Yuichi Yamazaki; Takashi Kosone; Norio Horigichi; Naondo Sohara; Ken Sato; Hitoshi Takagi; Kouichi Yoshinari; Masatomo Mori, Feb. 2007, LIVER INTERNATIONAL, 27, 1, 109, 119
  • Optimal follow-up time to determine the sustained virological response in patients with chronic hepatitis C receiving pegylated-interferon and ribavirin, Masashi Namikawa; Satoru Kakizaki; Yutaka Yata; Yuichi Yamazaki; Norio Horiguchi; Ken Sato; Hitoshi Takagi; Masatomo Mori, Jan. 2012, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27, 1, 69, 75
  • Hepatocyte growth factor overexpression ameliorates liver inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis, Hiroki Tojima; Satoru Kakizaki; Takashi Kosone; Norio Horiguchi; Yuichi Yamazaki; Ken Sato; Hitoshi Takagi; Masatomo Mori, Jun. 2012, HEPATOLOGY INTERNATIONAL, 6, 3, 620, 630
  • Ligand dependent hepatic gene expression profiles of nuclear receptors CAR and PXR, Hiroki Tojima; Satoru Kakizaki; Yuichi Yamazaki; Daichi Takizawa; Norio Horiguchi; Ken Sato; Masatomo Mori, Aug. 2012, TOXICOLOGY LETTERS, 212, 3, 288, 297
  • Response-guided peginterferon-alpha-2b plus ribavirin therapy for chronic hepatitis C patients with genotype 2 and high viral loads, Ken Sato; Hiroaki Hashizume; Yuichi Yamazaki; Norio Horiguchi; Satoru Kakizaki; Hitoshi Takagi; Masatomo Mori, Sep. 2012, HEPATOLOGY RESEARCH, 42, 9, 854, 863
  • Prevalence of nonalcoholic steatohepatitis in Japanese patients with morbid obesity undergoing bariatric surgery, Yosuke Seki; Satoru Kakizaki; Norio Horiguchi; Hiroaki Hashizume; Hiroki Tojima; Yuichi Yamazaki; Ken Sato; Motoyasu Kusano; Masanobu Yamada; Kazunori Kasama, Mar. 2016, JOURNAL OF GASTROENTEROLOGY, 51, 3, 281, 289
  • Malignant Peripheral Nerve Sheath Tumor of the Liver, Satoru Kakizaki; Norio Horiguchi; Toshiyuki Otsuka; Daichi Takizawa; Yuichi Yamazaki; Ken Sato; Yoshihiro Ohno; Motoyasu Kusano; Masanobu Yamada, 2016, INTERNAL MEDICINE, 55, 3, 245, 249
  • Combination therapy with daclatasvir and asunaprevir for dialysis patients infected with hepatitis C virus, Ken Sato; Yuichi Yamazaki; Tatsuya Ohyama; Takeshi Kobayashi; Norio Horiguchi; Satoru Kakizaki; Motoyasu Kusano; Masanobu Yamada, Mar. 2016, WORLD JOURNAL OF CLINICAL CASES, 4, 3, 88, 93
  • Early Decreases in alpha-Fetoprotein and Des-gamma-carboxy Prothrombin Predict the Antitumor Effects of Hepatic Transarterial Infusion Chemotherapy with Cisplatin (CDDP) Powder in Patients with Advanced Hepatocellular Carcinoma, Takeshi Hatanaka; Satoru Kakizaki; Yasushi Shimada; Daichi Takizawa; Kenji Katakai; Yuichi Yamazaki; Ken Sato; Motoyasu Kusano; Masanobu Yamada, 2016, INTERNAL MEDICINE, 55, 16, 2163, 2171
  • Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors, Hiroki Kamino; Yuichi Yamazaki; Kosuke Saito; Daich Takizawa; Satoru Kakizaki; Rick Moore; Masahiko Negishi, Jun. 2011, INTERNATIONAL JOURNAL OF ONCOLOGY, 38, 6, 1511, 1520
  • Nuclear Receptors CAR and PXR; therapeutic targets for cholestatic liver disease, Satoru Kakizaki; Daichi Takizawa; Hiroki Tojima; Norio Horiguchi; Yuichi Yamazaki; Masatomo Mori, Jun. 2011, FRONTIERS IN BIOSCIENCE-LANDMARK, 16, 2988, +
  • MK-0626, a selective DPP-4 inhibitor, attenuates hepatic steatosis in ob/ob mice, Tatsuya Ohyama; Ken Sato; Yuichi Yamazaki; Hiroaki Hashizume; Norio Horiguchi; Satoru Kakizaki; Masatomo Mori; Motoyasu Kusano; Masanobu Yamada, Nov. 2014, WORLD JOURNAL OF GASTROENTEROLOGY, 20, 43, 16227, 16235
  • Clinical and virological features of acute hepatitis E in Gunma prefecture, Japan between 2004 and 2015, Yuichi Yamazaki; Atsushi Naganuma; Yosuke Arai; Suguru Takeuchi; Takeshi Kobayashi; Satoshi Takakusagi; Takeshi Hatanaka; Takashi Hoshino; Masashi Namikawa; Hiroaki Hashizume; Daichi Takizawa; Tatsuya Ohyama; Hideyuki Suzuki; Norio Horiguchi; Hitoshi Takagi; Ken Sato; Satoru Kakizaki; Motoyasu Kusano; Shigeo Nagashima; Masaharu Takahashi; Hiroaki Okamoto; Masanobu Yamada, Apr. 2017, HEPATOLOGY RESEARCH, 47, 5, 435, 445
  • Spontaneous remission of hepatitis B virus reactivation during direct-acting antiviral agent-based therapy for chronic hepatitis C, Ken Sato; Takeshi Kobayashi; Yuichi Yamazaki; Satoshi Takakusagi; Norio Horiguchi; Satoru Kakizaki; Motoyasu Kusano; Masanobu Yamada, Nov. 2017, HEPATOLOGY RESEARCH, 47, 12, 1346, 1353
  • An Autopsy Case of Fulminant Hepatitis in a Patient with Multiple Sclerosis Treated by Interferon-Beta-1a, Yuichi Yamazaki; Aya Suzuki; Kimitoshi Hirayanagi; Yusuke Tsukagoshi; Ryota Uehara; Kazuhiko Horiguchi; Tatsuya Ohyama; Takuya Tomaru; Norio Horiguchi; Sumihito Nobusawa; Hayato Ikota; Ken Sato; Satoru Kakizaki; Motoyasu Kusano; Yoshio Ikeda; Hideaki Yokoo; Masanobu Yamada, 2017, INTERNAL MEDICINE, 56, 14, 1897, 1901
  • Full-length genomic sequences of new subtype 1g hepatitis E virus strains obtained from four patients with imported or autochthonous acute hepatitis E in Japan, Tsutomu Nishizawa; Putu Prathiwi Primadharsini; Masashi Namikawa; Yuichi Yamazaki; Satoko Uraki; Hiroshi Okano; Shinichiro Horiike; Tatsunori Nakano; Shintaro Takaki; Manri Kawakami; Shigeo Nagashima; Masaharu Takahashi; Hiroaki Okamoto, Nov. 2017, INFECTION GENETICS AND EVOLUTION, 55, 343, 349
  • Combination Therapy with Ombitasvir/Paritaprevir/Ritonavir for Dialysis Patients Infected with Hepatitis C Virus: A Prospective Multi-Institutional Study, Ken Sato; Kenichi Hosonuma; Yuichi Yamazaki; Takeshi Kobayashi; Satoshi Takakusagi; Norio Horiguchi; Satoru Kakizaki; Motoyasu Kusano; Hiroshi Ohnishi; Hiroaki Okamoto; Masanobu Yamada, Jan. 2017, TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 241, 1, 45, 53
  • Hydroxyurea-induced Pneumonitis in a Patient with Chronic Myelomonocytic Leukemia: An Autopsy Case., Hisao Imai; Nozomi Matsumura; Yuichi Yamazaki; Yuki Kanayama; Tomomi Masuda; Tomohito Kuwako; Yosuke Kamide; Taku Tomizawa; Shunichi Matsumoto; Takeki Mitsui; Kyoichi Kaira; Akihiro Ono; Yasuhiko Koga; Nobuyuki Shibusawa; Noriaki Sunaga; Takeshi Hisada; Hideaki Yokoo; Masanobu Yamada, 2015, Internal medicine (Tokyo, Japan), 54, 24, 3171, 6
  • Severe manifestation of acute hepatitis A recently found in Gunma, Japan, D Kanda; H Takagi; Y Hashimoto; Y Yamazaki; M Matsui; T Kosone; H Arai; T Ichikawa; H Nakajima; T Otsuka; A Kojima; K Sato; S Kakizaki; Y Matsuzaki; T Matsumoto; R Shimoda; M Kaneko; H Takayama; H Takahashi; T Abe; J Takezawa; M Mori, Jul. 2002, JOURNAL OF GASTROENTEROLOGY, 37, 7, 517, 522
  • Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity., Yuichi Yamazaki; Satoru Kakizaki; Norio Horiguchi; Hitoshi Takagi; Masatomo Mori; Masahiko Negishi, 14 Oct. 2005, World journal of gastroenterology, 11, 38, 5966, 72
  • Xenobiotic-Sensing Nuclear Receptors CAR and PXR as Drug Targets in Cholestatic Liver Disease, Satoru Kakizaki; Daichi Takizawa; Hiroki Tojima; Yuichi Yamazaki; Masatomo Mori, Nov. 2009, CURRENT DRUG TARGETS, 10, 11, 1156, 1163, Book review
  • New insights on the xenobiotic-sensing nuclear receptors in liver diseases - CAR and PXR-, Satoru Kakizaki; Yuichi Yamazaki; Daichi Takizawa; Masahiko Negishi, Sep. 2008, CURRENT DRUG METABOLISM, 9, 7, 614, 621, Book review
  • Non alcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) in comparison to non-Japanese patients, Satoru Kakizaki; Daichi Takizawa; Yuichi Yamazaki; Tatsuya Ohyama; Naondo Sohara; Takeshi Ichikawa; Ken Sato; Hiroshi Takagi; Masatomo Mori; Kazunori Kasama, Apr. 2008, GASTROENTEROLOGY, 134, 4, A370, A371, Summary international conference
  • Different outcomes of nosocomial infection with hepatitis C virus from the same origin, Satoru Kakizaki; Hitoshi Takagi; Yuichi Yamazaki; Naondo Sohara; Ken Sato; Takeaki Nagamine; Masatomo Mori, Jan. 2006, WORLD JOURNAL OF GASTROENTEROLOGY, 12, 4, 659, 661
  • Hepatocellular carcinoma in extremely elderly patients: An analysis of clinical characteristics, prognosis and patient survival, Gengo Tsukioka; Satoru Kakizaki; Naondo Sohara; Ken Sato; Hitoshi Takagi; Hirotaka Arai; Takehiko Abe; Mitsuo Toyoda; Kenji Katakai; Akira Kojima; Yuichi Yamazaki; Toshiyuki Otsuka; Yutaka Matsuzaki; Fujio Makita; Daisuke Kanda; Katsuhiko Horiuchi; Tetsuya Hamada; Mieko Kaneko; Hideyuki Suzuki; Masatomo Mori, Jan. 2006, WORLD JOURNAL OF GASTROENTEROLOGY, 12, 1, 48, 53
  • Overexpression of NK2 inhibits liver regeneration after partial hepatectomy in mice, Toshiyuki Otsuka; Norio Horiguchi; Daisuke Kanda; Takashi Kosone; Yuichi Yamazaki; Kazuhisa Yuasa; Naondo Sohara; Satoru Kakizaki; Ken Sato; Hitoshi Takagi; Glenn Merlino; Masatomo Mori, Dec. 2005, WORLD JOURNAL OF GASTROENTEROLOGY, 11, 47, 7444, 7449
  • Constitutive Active/Androstane Receptor Promotes Hepatocarcinogenesis in a Mouse Model of Non-Alcoholic Steatohepatitis, Daichi Takizawa; Satoru Kakizaki; Norio Horiguchi; Yuichi Yamazaki; Hiroki Tojima; Tatsuya Ohyama; Ken Sato; Masatomo Mori, May 2011, GASTROENTEROLOGY, 140, 5, S909, S909, Summary international conference
  • Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence, T. Ohyama; K. Sato; K. Kishimoto; Y. Yamazaki; N. Horiguchi; T. Ichikawa; S. Kakizaki; H. Takagi; T. Izumi; M. Mori, Feb. 2012, BRITISH JOURNAL OF PHARMACOLOGY, 165, 4B, 1173, 1187
  • Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver, Yuichi Yamazaki; Rick Moore; Masahiko Negishi, Nov. 2011, LABORATORY INVESTIGATION, 91, 11, 1624, 1633
  • Endoscopic treatment for esophageal varices complicated by Isaacs' syndrome involving difficulty with conventional sedation, Yuhei Suzuki; Yuichi Yamazaki; Hiroaki Hashizume; Takeshi Kobayashi; Tatsuya Ohyama; Norio Horiguchi; Ken Sato; Satoru Kakizaki; Motoyasu Kusano; Masanobu Yamada, 01 Feb. 2016, Clinical Journal of Gastroenterology, 9, 1, 27, 31
  • Elevated serum uric acid level was a notable adverse event during combination therapy with sofosbuvir and ribavirin, Ken Sato; Atsushi Naganuma; Tamon Nagashima; Takashi Hoshino; Daisuke Uehara; Yousuke Arai; Katsuhiko Horiuchi; Kazuhisa Yuasa; Hisashi Takayama; Hirotaka Arai; Takeshi Hatanaka; Tatsuya Ohyama; Hiroki Tahara; Naondo Sohara; Takeshi Kobayashi; Norio Horiguchi; Yuichi Yamazaki; Satoru Kakizaki; Motoyasu Kusano; Masanobu Yamada; Takayo Murase; Takashi Nakamura, 01 Feb. 2018, Hepatology Research, 48, 3, E347, E353
  • Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity, Yuichi Yamazaki; Satoru Kakizaki; Norio Horiguchi; Hitoshi Takagi; Masatomo Mori; Masahiko Negishi, Oct. 2005, WORLD JOURNAL OF GASTROENTEROLOGY, 11, 38, 5966, 5972
  • Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver., Yuichi Yamazaki; Rick Moore; Masahiko Negishi, Nov. 2011, Laboratory investigation; a journal of technical methods and pathology, 91, 11, 1624, 33
  • DDCにより誘導される肝障害、肝前駆細胞、オーバル細胞増殖を介した肝再生、修復における核内受容体CARの役割, 山崎 勇一; 柿崎 暁; 森 昌朋; 根岸 正彦, 2013, 56, 3, 301, 310
  • サプリメント(金時しょうがR)による薬物性肝障害の1例, 鈴木 悠平; 山崎 勇一; 橋爪 洋明; 大山 達也; 堀口 昇男; 佐藤 賢; 柿崎 暁; 山田 正信, 2015, 112, 1, 108, 114
  • Minimizing the effect of warfarin potassium during daclatasvir/asunaprevir combination therapy in a case of chronic hepatitis C after aortic dissection, Daisuke Uehara; Satoru Kakizaki; Takeshi Kobayashi; Satoshi Takakusagi; Norio Horiguchi; Yuichi Yamazaki; Ken Sato; Masanobu Yamada, 2017, Acta Hepatologica Japonica, 58, 1, 22, 27
  • 両下肢の壊疽性膿皮症を合併した潰瘍性大腸炎の1例, 富澤 琢; 山﨑 勇一; 中山 哲雄; 安岡 秀敏; 栗林 志行; 大山 達也; 堀口 昇男; 水出 雅文; 下山 康之; 佐藤 賢; 柿崎 暁; 河村 修; 草野 元康, 2015, 87, 1, 186, 187
  • The relationship between renin angiotensin system inhibitor and serum potassium increase during combination therapy with daclatasvir and asnaplevir for chronic hepatitis C, Yuichi Yamazaki; Ken Sato; Satoru Kakizaki; Tamon Nagashima; Hiroki Tojima; Hiroaki Hashizume; Tatsuya Ohyama; Norio Horiguchi; Motoyasu Kusano; Masanobu Yamada, 29 Jul. 2015, Acta Hepatologica Japonica, 56, 7, 324, 331
  • 輸血によるE型急性肝炎の1例, 小林 剛; 佐藤 賢; 山崎 勇一; 大山 達也; 堀口 昇男; 柿崎 暁; 草野 元康; 山田 正信; 横濱 章彦; 岡本 宏明, 2016, 105, 11, 2215, 2220
  • NAFLD/NASHモデルにおけるマクロファージ遊走阻止因子(MIF)の役割, 堀口 昇男; 柿崎 暁; 滝澤 大地; 植原 大介; 小林 剛; 戸島 博貴; 山崎 勇一; 佐藤 賢; 浦岡 俊夫, Oct. 2018, 日本消化器病学会雑誌, 115, 臨増大会, A740, A740
  • 神経性食思不振症に合併した多発肝腫瘤の二例, 長岡 潤; 竝川 昌司; 堀口 英; 甲賀 達也; 植原 大介; 岡野 祐大; 松井 綾子; 小林 剛; 椎名 啓介; 菅間 一乃; 高草木 智史; 戸島 洋貴; 長沼 篤; 堀口 昇男; 飯田 智広; 山崎 勇一; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, Oct. 2018, 日本消化器病学会雑誌, 115, 臨増大会, A802, A802
  • 肝細胞癌に対するダブルプラチナ療法の効果予測因子についての検討, 戸島 洋貴; 新井 弘隆; 鈴木 悠平; 滝澤 大地; 豊田 満夫; 高山 尚; 阿部 毅彦; 小林 剛; 堀口 昇男; 山崎 勇一; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, Sep. 2018, 肝臓, 59, Suppl.2, A687, A687
  • 上部消化管内視鏡検査を契機に診断にいたったシカゴ分類で分類不能の食道運動障害の1例, 佐藤 圭吾; 下山 康之; 保坂 浩子; 栗林 志行; 河村 修; 星 恒輝; 小林 剛; 入江 江美; 山田 俊哉; 中山 哲雄; 田中 寛人; 戸島 洋貴; 富澤 琢; 堀口 昇男; 山崎 勇一; 佐藤 賢; 柿崎 曉; 草野 元康; 浦岡 俊夫, Jun. 2018, Progress of Digestive Endoscopy, 93, Suppl., s94, s94
  • 治療に難渋した好酸球性胆管炎の1例, 西尾 麻由; 小林 剛; 戸島 洋貴; 堀口 昇男; 山崎 勇一; 佐藤 賢; 柿崎 暁; 浦岡 俊夫; 平戸 純子, Jun. 2018, 日本内科学会関東地方会, 642回, 20, 20
  • 群馬県における肝炎治療コーディネーター養成の取り組みと問題点, 堀口 昇男; 山崎 勇一; 柿崎 暁, Apr. 2018, 肝臓, 59, Suppl.1, A473, A473
  • 患者アンケートを実施してみえた痒みの顕在化 GLSG:Gunma Liver Study Group, 堀口 昇男; 柿崎 暁; 小林 剛; 戸島 洋貴; 山崎 勇一; 佐藤 賢; 橋爪 洋明; 濱田 哲也; 片貝 堅志; 竝川 昌司; 長沼 篤; 上野 敬史; 阿部 毅彦; 高草木 智史; 小曽根 隆; 高木 均, Mar. 2018, 日本消化器病学会雑誌, 115, 臨増総会, A344, A344
  • マウス脂肪性肝炎モデルにおけるMIF(マクロファージ遊走阻止因子)の役割, 堀口 昇男; 滝澤 大地; 柿崎 暁; 小林 剛; 戸島 洋貴; 山崎 勇一; 佐藤 賢; 草野 元康, Sep. 2017, 日本癌学会総会記事, 76回, P, 3304
  • 1型C型慢性肝炎に対する12週間投与DAA製剤による前向き多施設観察研究(中間成績), 佐藤 賢; 長沼 篤; 星野 崇; 植原 大介; 堀内 克彦; 湯浅 和久; 細沼 賢一; 長島 多聞; 新井 洋祐; 大山 達也; 中島 弘明; 蘇原 直人; 竝川 昌司; 高草木 智史; 小林 剛; 堀口 昇男; 山崎 勇一; 柿崎 暁; 山田 正信; 岡本 宏明, Apr. 2017, 肝臓, 58, Suppl.1, A305, A305
  • 当院におけるHCV感染血友病患者に対する直接作用型抗HCV薬治療に関する検討, 松村 郁子; 小川 孔幸; 柳澤 邦雄; 内海 英貴; 山崎 勇一; 佐藤 賢; 柿崎 暁; 合田 史; 半田 寛, Apr. 2017, 日本血栓止血学会誌, 28, 2, 224, 224
  • 食道胃接合部形態による逆流性食道炎のリスク評価, 栗林 志行; 保坂 浩子; 下山 康之; 星 恒輝; 深井 泰守; 小林 剛; 入江 江美; 山田 俊哉; 中山 哲雄; 田中 寛人; 高草木 智史; 富澤 琢; 水出 雅文; 堀口 昇男; 山崎 勇一; 佐藤 賢; 柿崎 暁; 河村 修; 草野 元康, Feb. 2017, 胃病態機能研究会誌, 49, 35, 35
  • 多発性筋炎合併間質性肺炎の治療中に急速な肝障害の進行を認め、非代償性肝硬変に至った1症例, 石北 悦子; 矢冨 正清; 塚越 優介; 鶴巻 寛朗; 山崎 勇一; 櫻井 麗子; 小野 昭浩; 古賀 康彦; 久田 剛志; 山田 正信, Dec. 2016, 日本内科学会関東地方会, 629回, 36, 36
  • 1型C型慢性肝炎に対して、22日間の内服でSVR24を得られたdaclatasvir/asunaprevir併用療法の1例, 佐藤 賢; 堀口 昇男; 小林 剛; 高草木 智史; 山崎 勇一; 柿崎 暁; 山田 正信, Oct. 2016, 肝臓, 57, Suppl.3, A782, A782
  • Assessment of Esophago-Gastric Junction Morphology and Barrier Function by Combined High Resolution Manometry and Endoscopy for Evaluating a Risk of Gastroesophageal Reflux Disease, Shiko Kuribayashi; Hiroko Hosaka; Akiyo Kawada; Junichi Akiyama; Yasumori Fukai; Takeshi Kobayashi; Tetsuo Nakayama; Taku Tomizawa; Hidetoshi Yasuoka; Tatsuya Ohyama; Masafumi Mizuide; Norio Horiguchi; Yuichi Yamazaki; Yasuyuki Shimoyama; Ken Sato; Satoru Kakizaki; Osamu Kawamura; Masanobu Yamada; Motoyasu Kusano, Apr. 2016, GASTROENTEROLOGY, 150, 4, S289, S289, Summary international conference
  • Hepatic angiosarcoma with dyskeratosis congenita, Satoru Kakizaki; Norio Horiguchi; Satoshi Hagiwara; Tatsuya Ohyama; Yuichi Yamazaki; Nobuyuki Shibusawa; Ken Sato; Motoyasu Kusano; Masanobu Yamada, Dec. 2015, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30, 329, 330, Summary international conference
  • 1b型高ウイルス量C型慢性肝炎に対するシメプレビル/ペグインターフェロン/リバビリン併用療法の包括化個別化医療に基づいた多施設共同前向き試験, 佐藤 賢; 長沼 篤; 高木 均; 長島 多聞; 山崎 勇一; 橋爪 洋明; 大山 達也; 堀口 昇男; 戸島 洋貴; 田原 博貴; 柿崎 暁; 山田 正信, Apr. 2015, 肝臓, 56, Suppl.1, A487, A487
  • Genotype 1b高ウイルス量のC型慢性肝炎に対するテラプレビル/ペグインターフェロンα2b/リバビリン3剤併用による包括化個別化治療, 佐藤 賢; 高木 均; 新井 弘隆; 鈴木 秀行; 長沼 篤; 滝澤 大地; 長島 多聞; 戸島 洋貴; 上野 敬史; 畑中 健; 橋爪 洋明; 堀口 昇男; 山崎 勇一; 柿崎 暁; 草野 元康; 山田 正信, Sep. 2014, 肝臓, 55, Suppl.2, A656, A656
  • 治療効果判定に腹部CT検査が有用であった好酸球性胃腸炎の1例, 井上 裕太; 山崎 勇一; 平山 結佳子; 金山 雄樹; 富澤 琢; 松本 俊一; 今井 久雄; 渋沢 信行; 草野 元康; 山田 正信, Sep. 2014, 608回, 30, 30
  • 群馬県におけるE型肝炎の最近2年間の発生状況, 山崎勇一; 竹内卓; 上野敬史; 畑中健; 橋爪洋明; 滝澤大地; 長沼篤; 堀口昇男; 佐藤賢; 柿崎暁; 高山尚; 高木均; 岡本宏明, 15 Sep. 2013, 日本消化器病学会雑誌, 110, A824
  • Final Results of a Clinical Trial of a 2-Week Lead-in Therapy With Interferon Beta Plus Ribavirin Before Peginterferon alpha-2B Plus Ribavirin for Chronic Hepatitis C With Genotype 1 and High Viral Loads, Ken Sato; Tatsuya Ohyama; Hiroaki Hashizume; Norio Horiguchi; Yuichi Yamazaki; Satoru Kakizaki; Masatomo Mori, May 2013, GASTROENTEROLOGY, 144, 5, S984, S984, Summary international conference
  • Amelioration of Hepatic Steatosis in Obese Mice by Mk-0626, a Selective alpha-Amino Amide Dipeptidyl Peptidase-4 Inhibitor, Tatsuya Ohyama; Ken Sato; Yuichi Yamazaki; Hiroaki Hashizume; Norio Horiguchi; Satoru Kakizaki; Masatomo Mori, May 2013, GASTROENTEROLOGY, 144, 5, S1018, S1018, Summary international conference
  • ヒトPXR選択的リガンドによるマウスCYP3A11の誘導におけるPXR核内移行の関与, 稲葉 明日実; 山崎 由貴; 小林 カオル; 戸島 洋貴; 山崎 勇一; 柿崎 暁; 遠藤 美佳; 阿部 千尋; 千葉 寛, Mar. 2013, 日本薬学会年会要旨集, 133年会, 3, 157, 157
  • A 2-Week Lead-in Therapy With Interferon Beta Plus Ribavirin Before Peginterferon alpha-2B Plus Ribavirin for Chronic Hepatitis C With Genotype 1 and High Viral Loads, Ken Sato; Hiroaki Hashizume; Norio Horiguchi; Yuichi Yamazaki; Satoru Kakizaki; Masatomo Mori, May 2012, GASTROENTEROLOGY, 142, 5, S959, S959, Summary international conference
  • Ligand Dependent Hepatic Gene Expression Profiles of Nuclear Receptors Car and PXR, Satoru Kakizaki; Hiroki Tojima; Yuichi Yamazaki; Daichi Takizawa; Norio Horiguchi; Naondo Sohara; Ken Sato; Masatomo Mori, May 2012, GASTROENTEROLOGY, 142, 5, S988, S988, Summary international conference
  • The Role of Macrophage Migration Inhibitory Factor (MIF) in Acute and Chronic Carbon Tetrachloride Induced Liver Injury: MIF Inhibits Chronic CCl4-Induced Liver Fibrosis, Daichi Takizawa; Norio Horiguchi; Satoru Kakizaki; Hiroki Tojima; Hiroaki Hashizume; Yuichi Yamazaki; Ken Sato; Bin Gao; Masatomo Mori, May 2012, GASTROENTEROLOGY, 142, 5, S973, S973, Summary international conference
  • Macrophage Migration Inhibitory Factor (MIF) Attenuates Liver Inflammation, Steatosis, and Fibrosis in Murine Non-Alcoholic Liver Disease Model, Norio Horiguchi; Daichi Takizawa; Satoru Kakizaki; Hiroki Tojima; Hiroaki Hashizume; Yuichi Yamazaki; Ken Sato; Bin Gao; Masatomo Mori, May 2012, GASTROENTEROLOGY, 142, 5, S921, S921, Summary international conference
  • 群馬県における肝疾患診療ネットワークの現状と取り組み, 山崎勇一; 柿崎暁; 堀口昇男; 橋爪洋明; 佐藤賢; 阿部毅彦; 高木均; 長嶺竹明; 森昌朋, 30 Apr. 2012, 肝臓, 53, Supplement 1, A351
  • NASH基礎 MIF(マクロファージ遊走阻止因子)は高脂肪食による肝障害、脂質沈着(Steatosis)、および肝線維化を抑制する, 堀口 昇男; 滝澤 大地; 柿崎 暁; 戸島 洋貴; 橋爪 洋明; 山崎 勇一; 佐藤 賢; 森 昌朋, Apr. 2012, 肝臓, 53, Suppl.1, A302, A302
  • 急性/慢性四塩化炭素肝炎モデルにおけるMIF(マクロファージ遊走阻止因子)の役割 MIFは肝線維化を抑制する, 滝澤 大地; 堀口 昇男; 柿崎 暁; 戸島 洋貴; 橋爪 洋明; 山崎 勇一; 佐藤 賢; 森 昌朋, Apr. 2012, 肝臓, 53, Suppl.1, A509, A509
  • 群馬県における肝炎医療費助成の現状と地域性, 山崎勇一; 柿崎暁; 橋爪洋明; 堀口昇男; 佐藤賢; 長嶺竹明; 森昌朋, 20 Feb. 2012, 日本内科学会雑誌, 101, 154
  • Response-Guided Therapy as an Effective Strategy on Peginterferon Alpha-2B Plus Ribavirin for Chronic Hepatitis C With Genotype 2 and a High Viral Road, Ken Sato; Hiroaki Hashizume; Yuichi Yamazaki; Norio Horiguchi; Satoru Kakizaki; Hitoshi Takagi; Masatomo Mori, May 2011, GASTROENTEROLOGY, 140, 5, S911, S911, Summary international conference
  • TGF-alpha Attenuates Hepatic Fibrosis: Possible Involvement of Matrix Metalloproteinase-1, Tatsuya Ohyama; Ken Sato; Yuichi Yamazaki; Norio Horiguchi; Takeshi Ichikawa; Satoru Kakizaki; Hitoshi Takagi; Masatomo Mori, May 2011, GASTROENTEROLOGY, 140, 5, S979, S979, Summary international conference
  • 群馬県におけるWilson病症例の検討―小児期と青年期発症例の比較―, 山崎勇一; 上野敬史; 石毛崇; 長沼篤; 大塚敏之; 佐藤賢; 柿崎暁; 阿部毅彦; 長嶺竹明; 森昌朋, 20 Feb. 2011, 日本内科学会雑誌, 100, 121
  • Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity, Satoru Kakizaki; Yuichi Yamazaki; Norio Horiguchi; Naondo Sohara; Ken Sato; Hitoshi Takagi; Masatomo Mori; Masahiko Negishi, Mar. 2006, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21, A208, A208, Summary international conference
  • DISSECTING THE ROLE OF MACROPHAGE INHIBITORY FACTOR (MIF) ON MURINE NAFLD/NASH MODEL, Norio Horiguchi; Daichi Takizawa; Daisuke Uehara; Takeshi Kobayashi; Hiroki Tojima; Yuichi Yamazaki; Ken Sato; Bin Gao; Satoru Kakizaki, May 2018, GASTROENTEROLOGY, 154, 6, S1155, S1155, Summary international conference
  • SIGNIFICANT REDUCTION OF MAC-2 BINDING PROTEIN GLYCOSYLATION ISOMER (M2BPGI) PROTEIN LEVELS IN PATIENTS WHO ACHIEVED SUSTAINED VIROLOGICAL RESPONSE (SVR) BUT NOT THOSE COULD NOT BY THE COMBINATION THERAPY OF DACLATASVIR/ASUNAPREVIR, Ken Sato; Satoshi Takakusagi; Takashi Kosone; Yuichi Yamazaki; Norio Horiguchi; Satoru Kakizaki; Hitoshi Takagi, May 2018, GASTROENTEROLOGY, 154, 6, S729, S729, Summary international conference
  • Dissecting The role of macrophage migration inhibitory (MIF) in murine NAFLD model, Horiguchi Norio; Daichi Takizawa; Satoru Kakizaki; Takeshi Kobayashi; Hiroki Tojima; Yuichi Yamazaki; Ken Sato; Motoyasu Kusano, Jan. 2018, CANCER SCIENCE, 109, 1122, 1122, Summary international conference
  • Macrophage migration inhibitory factor (MIF) attenuates hepatic steatosis and fibrosis but accelarates liver tumors development in murine NAFLD model, Norio Horiguchi; Daichi Takizawa; Satoru Kakizaki; Hiroki Tojima; Hiroaki Hashizume; Yuichi Yamazaki; Ken Sato; Bin Gao; Masatomo Mori, Oct. 2013, HEPATOLOGY, 58, 530A, 530A, Summary international conference
  • C型肝硬変合併透析患者の膵臓癌への陽子線治療後に発症した難治性胃潰瘍・胃毛細血管拡張症からの出血に対してアルゴンプラズマ凝固療法(APC)が奏功した一例, 椎名 啓介; 橋爪 洋明; 佐藤 賢; 斎藤 従道; 古賀 康彦; 堀口 昇男; 山崎 勇一; 柿崎 暁; 森 昌朋, 01 May 2011, 61, 2, 261, 261
  • IGFBP1 mediates pregnane X receptor-induced morphological changes and migration of hepatocellular carcinoma cells, Y. Yamazaki; S. Kodama; S. Kakizaki; M. Yamada; M. Negishi, Dec. 2015, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30, 329, 329, Summary international conference
  • Response-guided peginterferon alpha plus ribavirin therapy for hepatitis C patients with genotype 2 and high viral loads, 佐藤 賢; 橋爪 洋明; 山崎 勇一, Apr. 2012, 54, 4, 478, 485
  • NUCLEAR RECEPTOR CAR (NR1I3) IS ESSENTIAL FOR DDC-INDUCED LIVER INJURY AND OVAL CELL PROLIFERATION IN MOUSE LIVER, Yuichi Yamazaki; Satoru Kakizaki; Rick Moore; Masatomo Mori; Masahiko Negishi, Oct. 2011, HEPATOLOGY, 54, 956A, 956A, Summary international conference
  • 14. 巨大副腎転移をきたしたNASH合併肝細胞癌の一例(第25回群馬消化器病研究会), 山崎 勇一; 高木 均; 蘇原 直人; 市川 武; 柿崎 暁; 佐藤 賢; 森 昌朋; 新井 弘隆; 高山 尚; 田中 俊行; 小川 哲史; 阿部 毅彦; 柏原 賢治; 佐々木 惇; 伊藤 一人; 鈴木 和浩, 01 May 2007, 57, 2, 212, 212
  • Hepatocellular carcinoma in the extremely elderly patients: Clinical characteristics, prognosis and patient survival analysis., S Kakizaki; N Sohara; G Tsukioka; Y Nakajima; K Yuasa; N Horiguchi; Y Yamazaki; T Kosone; K Sato; H Takagi; M Mori, Apr. 2005, GASTROENTEROLOGY, 128, 4, A452, A452, Summary international conference
  • The 22nd Gunma Digestive Disease Conference, 堀口 昇男; 大塚 敏之; 山崎 勇一; 石田 克敏; 田中 良樹; 仁平 聡; 大野 順弘, 01 Nov. 2004, The KITAKANTO medical journal, 54, 4, 359, 360
  • 15.成人スティル病のステロイド療法中に合併したサイトメガロウイルス肝炎の一例(第21回群馬消化器病研究会), 滝澤 大地; 山崎 勇一; 堀口 昇男; 仁平 聡; 清水 直樹; 長坂 一三; 吉見 誠至; 原田 孝; 水間 春夫; 富岡 眞一; 大野 順弘; 高木 均; 森 昌朋, 01 Feb. 2004, 54, 1, 52, 52
  • 18.異なる経過をたどった血液型不適合肝移植の2例(第21回群馬消化器病研究会), 豊田 満夫; 長沼 篤; 長島 真美子; 饗場 正明; 新井 弘隆; 小野里 康博; 石原 弘; 阿部 毅彦; 神田 大輔; 蘇原 直人; 山崎 勇一; 小島 明; 高橋 良美; 高木 均; 森 昌朋, 01 Feb. 2004, 54, 1, 53, 53
  • Characteristics of cases of hepatitis E in Gunma prefecture: Small epidemics caused by the same subgenotype 3a strains, Yuichi Yamazaki; Takashi Ueno; Takeshi Hatanaka; Satoshi Takakusagi; Daichi Takizawa; Atsushi Naganuma; Takashi Kosone; Hiroaki Nakajima; Ken Sato; Satoru Kakizaki; Hitoshi Takagi; Toshio Uraoka; Masaharu Takahashi; Shigeo Nagashima; Hiroaki Okamoto, Aug. 2021, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 36, 87, 88, Summary international conference
  • NBNC肝癌の臨床病理学的検討, 植原 大介; 柿崎 暁; 戸島 洋貴; 小林 剛; 堀口 昇男; 山崎 勇一; 佐藤 賢; 畑中 健; 長沼 篤; 滝澤 大地; 新井 弘隆; 浦岡 俊夫, Oct. 2019, 肝臓, 60, Suppl.2, A707, A707
  • 高度黄疸を来した多中心性キャッスルマン病の1例, 塩原 理沙; 山崎 勇一; 小林 剛; 戸島 洋貴; 堀口 昇男; 下山 康之; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, Feb. 2019, 日本消化器病学会関東支部例会プログラム・抄録集, 353回, 46, 46
  • DAA治療不成功例に対するDAAによるサルベージ治療戦略, 佐藤 賢; 長沼 篤; 齋藤 秀一; 小林 剛; 戸島 洋貴; 山崎 勇一; 堀口 昇男; 柿崎 暁; 浦岡 俊夫; 岡本 宏明, Nov. 2018, 肝臓, 59, Suppl.3, A937, A937
  • 肝硬変の成因と病態の推移 群馬県における肝硬変の成因と病態の推移, 柿崎 暁; 長沼 篤; 上野 敬史; 飯塚 圭介; 畑中 健; 須賀 孝慶; 齋藤 秀一; 堀口 英; 滝澤 大地; 新井 弘隆; 戸島 洋貴; 山崎 勇一; 佐藤 賢; 浦岡 俊夫, Apr. 2023, 64, Suppl.1, A249, A249
  • COVID19ワクチン接種後に薬剤性肝障害と鑑別を要した自己免疫性肝炎の1例, 田村 優樹; 佐藤 賢; 清水 創一郎; 村上 立真; 金山 雄樹; 戸島 洋貴; 山崎 勇一; 浦岡 俊夫, Apr. 2023, 64, Suppl.1, A321, A321
  • 腹水濾過濃縮再静注法が有効であった直腸癌化学療法後の門脈圧亢進症による難治性腹水の1例, 田村 優樹; 山崎 勇一; 清水 創一郎; 村上 立真; 金山 雄樹; 戸島 洋貴; 佐藤 賢; 浦岡 俊夫, Apr. 2023, 374回, 30, 30

Presentations

  • Liver Injury in Patients with COVID-19 Who Received Dexamethasone Monotherapy, Yuichi Yamazaki, Yuki Kanayama, Daisuke Uehara, Takayoshi Suga, Hirohito Tanaka, Hiroki Tojima , Shiko Kuribayashi, Ken Sato, Satoru Kakizaki and Toshio Uraoka, APASL2023, 15 Feb. 2023, 15 Feb. 2023, 18 Feb. 2023, English, Taiwan, Province of China
  • COVID-19妊婦の肝障害についての検討, 山崎 勇一, JDDW2022, 27 Oct. 2022, 27 Oct. 2022, 30 Oct. 2022, Japanese, Japan
  • 多発肺転移にレンバチニブが奏功し、休薬後に腹腔内出血を生じた肝細胞癌の一剖検例, 山崎 勇一 , 植原 大介 , 金山 雄樹 , 須賀 孝慶 , 戸島 洋貴 , 佐藤 賢 , 柿崎 暁 , 浦岡 俊夫, 第43回日本肝臓学会東部会, 03 Dec. 2020, 03 Dec. 2020, 05 Dec. 2020
  • Nuclear xenobiotic receptor CAR is essential for DDC to proliferate oval cells in mouse liver, AASLD, 2011
  • Nuclear xenobiotic receptor CAR is essential for DDC to proliferate oval cells in mouse liver., 16th North American Regional Meeting of ISSX,, 2009
  • Nuclear xenobiotic receptor CAR is essential for DDC to proliferate oval cells in mouse liver, MDO, 2010
  • Clinical features of acute liver failure in Gunma University Hospital., APASL2013, 2013
  • The first acute hepatitis E infection with a Spanish type genotype 3f strain in Japan., APASL2013, 2013
  • Clinical Features of acute hepatitis E recently found in Gunma prefecture, Japan, APASL2014, 2014
  • IGFBP 1 mediates PXR-induced morphological changes and migration of HCC cells., APDW2015, 2015
  • Clinical and virological features of acute hepatitis E in Gunma prefecture, Japan between 2004 and 2015, APASL2017, 2017
  • The first acute hepatitis E infection with a Spanish type genotype 3f strain in Japan., APASL2013, 2013
  • E型急性肝炎30例の臨床的、ウイルス学的特徴, 2016
  • 肝細胞癌株におけるIGFBP-1を介した核内受容体PXR活性化による形態変化、細胞遊走, 2015
  • 群馬県におけるE型肝炎の最新の動向, 山崎勇一, 第56回日本肝臓学会総会, 28 Aug. 2020, 28 Aug. 2020, 29 Aug. 2020
  • 当院におけるCOVID-19患者の肝障害についての検討, 山崎勇一, 第56回日本肝臓学会総会 緊急特別企画 肝疾患診療におけるCOVID-19への対応, 28 Aug. 2020, 28 Aug. 2020, 29 Aug. 2020
  • An autopsy case of multicentric Castleman disease presenting with severe jaundice, Yuichi Yamazaki, APASL2022, 30 Mar. 2022, 30 Mar. 2022, 03 Apr. 2022, English
  • 全科協力体制下でのCOVID-19診療における内科医かつ消化器内科医の役割, 山崎 勇一, 第63回 日本消化器病学会大会, 04 Nov. 2021, 04 Nov. 2021, 07 Nov. 2021, Japanese
  • Characteristics of cases of hepatitis E in Gunma prefecture: small epidemics caused by the same subgenotype 3a strains., Yuichi Yamazaki, APDW2021, 19 Aug. 2021, 19 Aug. 2021, 22 Aug. 2021, English
  • 当院におけるアルコール関連疾患及び肝疾患の現状, 第109回日本消化器病学会総会, 07 Apr. 2023, 06 Apr. 2023, 08 Apr. 2023
  • 肝外門脈閉塞症に伴う求肝性の静脈瘤破裂に対して経皮経肝的静脈瘤塞栓術(PTO)と門脈ステント留置術を行った2例, Aung Paing Moe; 村上 立真; 清水 創一郎; 金山 雄樹; 戸島 洋貴; 山崎 勇一; 佐藤 賢; 浦岡 俊夫, 肝臓, Oct. 2023, Oct. 2023, Oct. 2023, Japanese
  • 肝細胞癌に対する定位放射線治療の有効性と安全性, 柴崎 充彦; 新井 弘隆; 舘山 夢生; 滝澤 大地; 甲賀 達也; 飯塚 圭介; 上野 敬史; 高草木 智史; 高木 均; 金山 雄樹; 戸島 洋貴; 山崎 勇一; 浦岡 俊夫, 肝臓, Sep. 2023, Sep. 2023, Sep. 2023, Japanese
  • 当院における急性肝不全症例の臨床的検討, 田村 優樹; 山崎 勇一; 清水 創一郎; 村上 立真; 金山 雄樹; 戸島 洋貴; 佐藤 賢; 柿崎 暁; 浦岡 俊夫, 肝臓, Sep. 2023, Sep. 2023, Sep. 2023, Japanese
  • 肝細胞癌のカテーテル治療による肝予備能変化と寄与する因子の検討, 滝澤 大地; 新井 弘隆; 柴崎 充彦; 舘山 夢生; 戸島 洋貴; 金山 雄樹; 山崎 勇一; 浦岡 俊夫, 肝臓, Sep. 2023, Sep. 2023, Sep. 2023, Japanese
  • 無菌性膿瘍症候群を伴う潰瘍性大腸炎にJAK阻害薬が著効した一例, 星野 駿介; 橋本 悠; 喜多 碧; 都丸 翔太; 糸井 祐貴; 佐藤 圭吾; 村上 立真; 金山 雄樹; 善如寺 暖; 清水 雄大; 保坂 浩子; 田中 寛人; 戸島 洋貴; 栗林 志行; 山崎 勇一; 竹内 洋司; 浦岡 俊夫, 日本消化器病学会関東支部例会プログラム・抄録集, Sep. 2023, Sep. 2023, Sep. 2023, Japanese
  • 悪性症候群を合併した特発性急性膵炎の1例, 井戸 健太; 善如寺 暖; 喜多 碧; 都丸 翔太; 糸井 祐貴; 佐藤 圭吾; 村上 立真; 橋本 悠; 金山 雄樹; 清水 雄大; 保坂 浩子; 田中 寛人; 戸島 洋貴; 栗林 志行; 山崎 勇一; 竹内 洋司; 浦岡 俊夫, 日本消化器病学会関東支部例会プログラム・抄録集, Jul. 2023, Jul. 2023, Jul. 2023, Japanese
  • レムデシビル投与及び侵襲ストレスによる複合的な要因によりC型肝炎ウイルス排除を達成したと考えられるC型慢性肝炎の1例, 佐藤賢; 佐藤賢; 山崎勇一; 村上立真; 金山雄樹; 戸島洋貴; 調憲; 浦岡俊夫, 肝臓, 2024, 2024, 2024
  • HBV-B4株に父子水平感染したと推定される日本在住ベトナム人女性B型慢性肝炎の1例, 佐藤賢; 佐藤賢; 山崎勇一; 村上立真; 金山雄輝; 戸島洋貴; 堀口英; 福地達; 岡本宏明; 浦岡俊夫, 肝臓, 2024, 2024, 2024
  • AFP-L3分画上昇が発見の契機となったAFP産生胃癌の1切除例, 相原沙代子; 佐藤圭吾; 舘山夢生; 村上立真; 戸島洋貴; 山崎勇一; 竹内洋司; 中澤信博; 佐伯浩司; 浦岡俊夫, 日本消化器病学会関東支部例会プログラム・抄録集, 2024, 2024, 2024
  • 肝細胞癌のB-TACE治療の効果と予後に寄与する因子の検討, 滝澤大地; 新井弘隆; 柴崎充彦; 舘山夢生; 金山雄樹; 戸島洋貴; 山崎勇一; 浦岡俊夫, 肝臓, 2024, 2024, 2024
  • EUS-TAが診断に有用であった偽性アカラシアを呈した食道胃接合部癌の一例, 冨澤佳那子; 善如寺暖; 喜多碧; 石渡栞; 都丸翔太; 舘山夢生; 糸井祐貴; 成瀬智康; 佐藤圭吾; 村上立真; 橋本悠; 清水雄大; 保坂浩子; 田中寛人; 戸島洋貴; 栗林志行; 栗林志行; 山崎勇一; 竹内洋司; 浦岡俊夫, Progress of Digestive Endoscopy, 2024, 2024, 2024
  • Different regulation of cytochrome P450 3a in liver and small intestine by cholesterol and cholic acid feeding in mice, 品川千聖; 峰岸元気; 山崎勇一; 柿崎暁; 宮嶋篤志; 小林カオル, 日本薬学会年会要旨集(Web), 2024, 2024, 2024
  • B型肝炎無症候性キャリア妊婦へ母子感染予防目的に核酸アナログ製剤を投与,出産後に中止した後に急性増悪を来した症例, 高田良; 清水創一郎; 福地達; 菅間一乃; 舘山夢生; 村上立真; 戸島洋貴; 山崎勇一; 岡本宏明; 浦岡俊夫, 肝臓, 2024, 2024, 2024
  • 切除不能肝細胞癌に対するデュルバルマブとトレメリムマブ併用療法の検討:多施設共同研究, 金山雄樹; 畑中健; 福地達; 上野敬史; 齋藤秀一; 竝川昌司; 山崎勇一; 新井弘隆; 柿崎暁; 浦岡俊夫, 肝臓, 2024, 2024, 2024
  • Prevotella属による副鼻腔炎を契機に黄疸の増悪をきたし,抗生剤治療により改善した原発性硬化性胆管炎の1例, 舘山夢生; 山崎勇一; 村上立真; 金山雄樹; 戸島洋貴; 浦岡俊夫, 肝臓, 2024, 2024, 2024
  • キサンチン酸化還元酵素の網羅的な肝疾患における意義, 佐藤賢; 佐藤賢; 長沼篤; 長島多聞; 新井洋佑; 金山雄樹; 村上立真; 村上立真; 上原早苗; 植原大介; 山崎勇一; 中村敬志; 浦岡俊夫, 肝臓, 2024, 2024, 2024

Research Projects

  • 01 Apr. 2020, 31 Mar. 2023, 20K08302
  • Apr. 2020, Mar. 2025, 20K08374
  • The role of nuclear receptor CAR in the pathogenesis of intrahepatic cholangiocellular carcinoma, Kakizaki Satoru, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gunma University, 01 Apr. 2017, 31 Mar. 2021, The aim of this study was to investigate the role of nuclear receptor CAR (constitutive androstane receptor) in the pathogenesis of intrahepatic cholangiocarcinoma. Thioacetamide (TAA) was administered to CAR knockout and wild-type mice to create a chemical carcinogenic model of cholangiocarcinoma. Cholangiocarcinoma developed after 24-weeks TAA administration. However, there were no significant differences between the two groups. In the chemical carcinogenesis model of hepatocellular carcinoma, it has been reported that carcinogenesis is significantly suppressed in CAR knockout mice. However, it is not suppressed in the TAA-induced cholangiocarcinoma model used in this study., 17K08387
  • Apr. 2017, Mar. 2022, 17K09453
  • The role of a transcriptional coactivator (PDIP1) that functions as a transcriptional coregulator of several nuclear receptors in the physiopathological process of the liver, SATO KEN; Satoh Tetsurou; Yoshino Satoshi; Gyao Bin; Tahara Hiroki; Nakajima Yoshimi; Ohyama Tatsuya; Takizawa Daichi; Tojima Hiroki, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gunma University, 01 Apr. 2014, 31 Mar. 2018, PDIP1 regulates target gene expression through nuclear receptor that is a kind of intracellular proteins. In addition, there is a difference of the extent of liver fibrosis that is caused by the stimuli which accelerate liver fibrosis between PDIP1 knock out mice in which the function of PDIP1 is lost and wild type mice in which the function of PDIP1 is maintained. There is also a difference of the extent of liver tumor that is caused by the stimuli which induce liver tumor between PDIP1 knock out mice and wild type mice. The mechanisms of the differences of liver fibrosis and tumor were analyzed and clarified., 26460983
  • The role of nuclear receptors PXR/CAR in the pathogenesis of inflammatory bowel diseases., Kakizaki Satoru; YOSHINARI Kouichi; TAKIZAWA Daichi; TOJIMA Hiroki; TAHARA Hiroki, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gunma University, 01 Apr. 2013, 31 Mar. 2017, The aim of this study was to investigate the role of nuclear receptors PXR and CAR in the pathogenesis of inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease. Wild-type, Pxr-null, Car-null, and Pxr/Car-double null mice were treated with a PXR/CAR agonist or vehicle in a dextran sodium sulfate (DSS)-induced IBD model. PXR and CAR ameliorate DSS-induced ulcerative colitis model via inhibiting inflammatory cytokines and apoptosis.PXR and CAR agonists are promising agents for the treatment of IBD., 25460941
  • The role of nuclear receptor CAR in the liver regeneration and repair madiated by oval cell proliferation., Yamazaki Yuichi; YOSHINARI Kouichi; TOJIMA Hiroki; TAHARA Hiroki, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gunma University, 01 Apr. 2012, 31 Mar. 2017, We have demonstrated that choline-deficient DL-ethionine supplemented (CDE) diet activates the nuclear receptor constitutive active/androstane receptor (CAR), resulting in proliferation of oval cells in mouse liver. Activation of CAR by CDE was shown by cytochrome P450 (CYP)2B10 and DNA damage-induced protein 45 family (GADD45)β mRNA induction after feeding a CDE diet to Car+/+ mice.Unlike 3,5-diethoxycarbonyl-1,4-dihydrocollidine containing diet, the liver damage, and oval cell proliferation were found in both Car+/+ and Car-/- mice after feeding a CDE diet.There was no significant difference of the EpCAM positive cells containing bile duct epithelial cells and liver progenitor cells between the Car+/+ and Car-/- mice as a result of immunostaining analysis, 24590954
  • The role of nuclear receptor coactivator PDIP1 in non-alcholic steatohepatitis, Sato Ken; SATOH tetsurou, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gunma University, 2011, 2013, Methionine-choline-deficient diet (MCD diet) has been established to use to make an animal model of non-alchoholic steatohepatitis. In PPAR gamma DNA-binding domain-interacting protein1 (PDIP1) knockout mice, serum ALT and TG, and hepatic fatty deposition, inflammation, and fibrosis were significantly reduced compared to wild type mice. Besides, the expressions of hepatic lipid-related genes have changed and hepatic inflammatory cytokines and fibrogenic genes were significantly reduced compared to wild type mice. Thus, we showed that non-alchoholic steatohepatitis was ameliorated in PDIP1 knockout mice., 23590959
  • サルコペニア高齢者の薬物代謝能力及び相互作用評価システムの開発と副作用リスク回避, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gunma University, Apr. 2022, Mar. 2025, Coinvestigator, 22K06763
  • 01 Apr. 2023, 31 Mar. 2026, 23K08771

Social Contribution

Social Contribution

  • Liver Cirrhosis Symposium, 07 Feb. 2023, 07 Feb. 2023
  • 肝臓内科医のためのLEN-TACE Academy 2022 夏の陣, 13 Sep. 2022, 13 Sep. 2022
  • 第一回群馬アルコール関連問題連絡会, 07 Jun. 2022, 07 Jun. 2022
  • 睡眠薬適正使用セミナー, 08 Mar. 2022, 08 Mar. 2022, Lecture
  • 国立研究開発法人日本医療研究開発機構 (AMED)委託研究費 感染症実用化研究事業 肝炎等克服実用化研究事業 肝炎等克服緊急対策研究事業 「経口感染によるウイルス性肝炎(A型及びE型)の感染防止、病態解明、治療等に関する研究」(経口肝炎班), 2020, 2020
  • 国立研究開発法人日本医療研究開発機構 (AMED)委託研究費 感染症実用化研究事業 肝炎等克服実用化研究事業 肝炎等克服緊急対策研究事業 「経口感染によるウイルス性肝炎(A型及びE型)の感染防止、病態解明、治療等に関する研究」(経口肝炎班), 2021, 2021
  • 第1回ノベルジン臨床応用研究会, 23 Nov. 2021, 23 Nov. 2021, Lecture
  • 第19回群馬肝疾患制御研究会, 06 Jan. 2022, 06 Jan. 2022, Lecture
  • 第20回群馬肝疾患制御研究会, 12 Jan. 2023, 12 Jan. 2023, Lecture
  • 肝臓内科医のためのLEN-TACE Academy 2023 冬の陣, 09 Mar. 2023, 09 Mar. 2023
  • 国立研究開発法人日本医療研究開発機構 (AMED)委託研究費 感染症実用化研究事業 肝炎等克服実用化研究事業 肝炎等克服緊急対策研究事業 「経口感染によるウイルス性肝炎(A型及びE型)の感染防止、病態解明、治療等に関する研究」(経口肝炎班), 2022, 2022
  • 第8回群馬消化管・肝胆膵腫瘍研究会, 11 Nov. 2023, 11 Nov. 2023
  • 第180回群馬肝癌検討会, 04 Dec. 2023, 04 Dec. 2023
  • Liver Disease Online Seminar, 19 Dec. 2023, 19 Dec. 2023
  • 第21回群馬肝疾患制御研究会, 11 Jan. 2024, 11 Jan. 2024, Lecture
  • 第21回群馬肝疾患制御研究会, 09 Jan. 2025, 09 Jan. 2025, Lecture
  • HCC Immuno-Oncology Seminar, 25 Nov. 2024, 25 Nov. 2024
  • 第43回群馬肝臓研究会, 27 Jul. 2024, 27 Jul. 2024


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