Researcher Profile and Settings

Researcher

• Name

  KUROSAWA Aya

Affiliation

• Division of Materials and Environment（Department of Food Science and Engineering）, Assistant Professor

Profile and Settings

• Name

  Kurosawa, Aya

Affiliation

• Gunma University, Assistant Professor

Affiliation

• Affiliation

  Graduate School of Science and Technology

Education

• 2008, Yokohama City University, Graduate
• 2003, Tokyo University of Science
• 2001, Tokyo University of Science, Faculty of Science and Technology, Applied Biological Science

Degree

• Ph.D

Association Memberships

• Jul. 2023
• SOCIETY FOR FREE RADICAL RESEARCH JAPAN
• THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
• THE JAPANESE RADIATION RESEARCH SOCIETY
• Radiation Biology Research Communications

Research Experience

• Apr. 2014, 9999, Gunma University, Graduate School of Science and Technology, Assistant prof lv
• Feb. 2011, Mar. 2014, Yokohama City University, Graduate School of Nanobioscience, Graduate, Assistant prof lv
• Apr. 2008, Jan. 2011, Yokohama City University, Researcher postdoc lv
• Dec. 2017, 9999, Gunma University, Center for Food Science and Wellness, Assistant prof lv
• Mar. 2019, Dec. 2019, Technical University of Darmstadt, Researcher postdoc lv, visiting scientist

Research Activities

Research Areas

• Environmental science/Agricultural science, Environmental effects of radiation
• Environmental science/Agricultural science, Environmental effects of chemicals

Research Interests

• 必須項目の入力がありません
• maintenance of genome integrity
• non-homologous end-joining
• DNA double-strand break

Published Papers

• SALL1 functions as a tumor suppressor in hepatocellular carcinoma cells., Yoshifumi Saito, Sora Miyakawa, Shotaro Ando, Carlos Ichiro Kasano-Camenos, I Wayan Sumardika, Akari Obayashi, Aoi Morimoto, Aya Kurosawa, Masakiyo Sakaguchi, Kazumi Ninomiya, Yusuke Inoue, Sep. 2025, Biochem Biophys Res Commun, 778, 8, 152385, Scientific journal
• Sulforaphane Induces Transient Reactive Oxygen Species-Mediated DNA Damage in HeLa Cells, Sakine Kobayashi, Seiya Nishiba, Chinatsu Sato, Kazuya Toriumi, Yuduki Someya, Noritaka Adachi, Shigeki Takeda, Aya Kurosawa, Jan. 2025, Genes to Cells, 30, 1, e13190, Scientific journal
• Quercetin exhibits cytotoxicity in cancer cells by inducing two-ended DNA double-strand breaks, Yuduki Someya, Shinta Saito, Shigeki Takeda, Noritaka Adachi, Aya Kurosawa, 20 Dec. 2024, Biochemical and Biophysical Research Communications, 739, 150977, Scientific journal
• Arsenic affects homologous recombination and single-strand annealing but not end-joining pathways during DNA double-strand break repair, Aya Kurosawa, Shinta Saito, Mikiko Sakurai, Mizuki Shinozuka, Yuduki Someya, Noritaka Adachi, 02 Aug. 2023, The FEBS journal, 290, 22, 5313, 5321, Scientific journal
• A cell system-assisted strategy for evaluating the natural anti-oxidant-induced double-stranded DNA break (DSB) style., Yuduki Someya, Sakine Kobayashi, Kazuya Toriumi, Shigeki Takeda, Noritaka Adachi, Aya Kurosawa, Feb. 2023, Genes, 14, 2, 420, Scientific journal
• Autophosphorylation and Self-Activation of DNA-Dependent Protein Kinase, Aya Kurosawa, 19 Jul. 2021, Genes, 12, 7, 1091, Scientific journal

  DOI
• Complex genetic interactions between DNA polymerase beta and the NHEJ ligase., Aya Kurosawa; Hiroyuki Kuboshima; Noritaka Adachi, Jan. 2020, The FEBS journal, 287, 2, 377, 385, Scientific journal

  DOI
• GPR31 and GPR151 are activated under acidic conditions., Misaki Mashiko; Aya Kurosawa; Yuki Tani; Takahi Tsuji; Shigeki Takeda, May 2019, Journal of biochemistry

  DOI
• A novel partial agonist of GPBA reduces blood glucose level in a murine glucose tolerance test, Rina Enomoto; Aya Kurosawa; Yoshiaki Nikaido; Misaki Mashiko; Toshihiko Saheki; Nozomi Nakajima; Satoshi Kuroiwa; Michinari Otobe; Maki Ohsaki; Kazuya Tooyama; Yusuke Inoue; Nobuo Kuwabara; Osamu Kikuchi; Tadahiro Kitamura; Itaru Kojima; Yuko Nakagawa; Tamio Saito; Hiroyuki Osada; Mizuko Futahashi; Hideki Sezutsu; Shigeki Takeda, Nov. 2017, European Journal of Pharmacology, 814, 130, 137, Scientific journal

  DOI
• Mechanistic basis for increased human gene targeting by promoterless vectors-roles of homology arms and Rad54 paralogs, Shinta Saito; Aya Kurosawa; Noritaka Adachi, Sep. 2017, FEBS JOURNAL, 284, 17, 2748, 2763, Scientific journal

  DOI
• Mutations in XRCC4 cause primordial dwarfism without causing immunodeficiency, Shinta Saito; Aya Kurosawa; Noritaka Adachi, Aug. 2016, JOURNAL OF HUMAN GENETICS, 61, 8, 679, 685, Scientific journal

  DOI
• Identification and molecular docking studies for novel inverse agonists of SREB, super conserved receptor expressed in brain, Toshihiro Yanai; Aya Kurosawa; Yoshiaki Nikaido; Nozomi Nakajima; Tamio Saito; Hiroyuki Osada; Ayumu Konno; Hirokazu Hirai; Shigeki Takeda, Jul. 2016, GENES TO CELLS, 21, 7, 717, 727, Scientific journal

  DOI
• In vivo and in vitro evaluation of novel mu-opioid receptor agonist compounds, Yoshiaki Nikaido; Aya Kurosawa; Hitomi Saikawa; Satoshi Kuroiwa; Chiharu Suzuki; Nobuo Kuwabara; Hazime Hoshino; Hideaki Obata; Shigeru Saito; Tamio Saito; Hiroyuki Osada; Isao Kobayashi; Hideki Sezutsu; Shigeki Takeda, Nov. 2015, European journal of pharmacology, 767, 193, 200, Scientific journal

  DOI
• Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining, Mario Moscariello; Radi Wieloch; Aya Kurosawa; Fanghua Li; Noritaka Adachi; Emil Mladenov; George Iliakis, Jul. 2015, DNA REPAIR, 31, 29, 40, Scientific journal

  DOI
• Analysis of the Role of Homology Arms in Gene-Targeting Vectors in Human Cells, Ayako Ishii; Aya Kurosawa; Shinta Saito; Noritaka Adachi, Sep. 2014, PLOS ONE, 9, 9, e108236, Scientific journal

  DOI
• DNA Ligase IV and Artemis Act Cooperatively to Suppress Homologous Recombination in Human Cells: Implications for DNA Double-Strand Break Repair, Aya Kurosawa; Shinta Saito; Sairei So; Mitsumasa Hashimoto; Kuniyoshi Iwabuchi; Haruka Watabe; Noritaka Adachi, 14 Aug. 2013, PLoS ONE, 8, 8, e72253, Scientific journal

  DOI
• Interference in DNA Replication Can Cause Mitotic Chromosomal Breakage Unassociated with Double-Strand Breaks, Mari Fujita; Hiroyuki Sasanuma; Kimiyo N. Yamamoto; Hiroshi Harada; Aya Kurosawa; Noritaka Adachi; Masato Omura; Masahiro Hiraoka; Shunichi Takeda; Kouji Hirota, Apr. 2013, PLOS ONE, 8, 4, e60043, Scientific journal

  DOI
• Both CpG Methylation and Activation-Induced Deaminase Are Required for the Fragility of the Human bcl-2 Major Breakpoint Region: Implications for the Timing of the Breaks in the t(14;18) Translocation, Xiaoping Cui; Zhengfei Lu; Aya Kurosawa; Lars Klemm; Andrew T. Bagshaw; Albert G. Tsai; Neil Gemmell; Markus Mueschen; Noritaka Adachi; Chih-Lin Hsieh; Michael R. Lieber, Mar. 2013, MOLECULAR AND CELLULAR BIOLOGY, 33, 5, 947, 957, Scientific journal

  DOI
• Endogenous factors causative of spontaneous DNA damage that leads to random integration in human cells., 10. Haruna Kamekawa, Aya Kurosawa, Masumi Umehara, Eriko Toyoda, Noritaka Adachi., 2013, Gene Technology, 2, 1000105
• Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs, Shruti Malu; Pablo De Ioannes; Mikhail Kozlov; Marsha Greene; Dailia Francis; Mary Hanna; Jesse Pena; Carlos R. Escalante; Aya Kurosawa; Hediye Erdjument-Bromage; Paul Tempst; Noritaka Adachi; Paolo Vezzoni; Anna Villa; Aneel K. Aggarwal; Patricia Cortes, May 2012, JOURNAL OF EXPERIMENTAL MEDICINE, 209, 5, 955, 963, Scientific journal

  DOI
• Nucleofection-based gene targeting in human pre-B cells, Aya Kurosawa; Shinta Saito; Mikako Mori; Noritaka Adachi, Jan. 2012, GENE, 492, 1, 305, 308, Scientific journal

  DOI
• Functions and Regulation of Artemis: A Goddess in the Maintenance of Genome Integrity, Aya Kurosawa; Noritaka Adachi, Sep. 2010, JOURNAL OF RADIATION RESEARCH, 51, 5, 503, 509, Scientific journal

  DOI
• Topoisomerase II alpha inhibition following DNA transfection greatly enhances random integration in a human pre-B lymphocyte cell line, Eriko Toyoda; Aya Kurosawa; Haruna Kamekawa; Noritaka Adachi, May 2009, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 382, 3, 492, 496, Scientific journal

  DOI
• Heterozygous Disruption of the DNA Topoisomerase I Gene Confers Cellular Resistance to Camptothecin in Human Cells, Eriko Toyoda; Aya Kurosawa; Michihiko Fujii; Noritaka Adachi, Apr. 2009, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 32, 4, 724, 727, Scientific journal

  DOI
• [Mechanisms of chromosomal DNA strand break repair in human cells]., Adachi N; Yano K; Kurosawa A, Mar. 2009, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54, 4 Suppl, 472, 478
• Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting, Susumu Iiizumi; Aya Kurosawa; Sairei So; Yasuyuki Ishii; Yuichi Chikaraishi; Ayako Ishii; Hideki Koyama; Noritaka Adachi, Nov. 2008, NUCLEIC ACIDS RESEARCH, 36, 19, 6333, 6342, Scientific journal

  DOI
• NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform, Eriko Toyoda; Shigehide Kagaya; Ian G. Cowell; Aya Kurosawa; Keiichi Kamoshita; Kiyohiro Nishikawa; Susumu Iiizumi; Hideki Koyama; Caroline A. Austin; Noritaka Adachi, Aug. 2008, JOURNAL OF BIOLOGICAL CHEMISTRY, 283, 35, 23711, 23720, Scientific journal

  DOI
• Cell sorting analysis of cell cycle-dependent X-ray sensitivity in end joining-deficient human cells, Kuniyoshi Iwabuchi; Mitsumasa Hashimoto; Tadashi Matsui; Aya Kurosawa; Noritaka Adachi; Takayasu Date, Aug. 2008, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 372, 4, 662, 667, Scientific journal

  DOI
• The requirement of artemis in double-strand break repair depends on the type of DNA damage, Aya Kurosawa; Hideki Koyama; Shinichi Takayama; Kensuke Miki; Dai Ayusawa; Michihiko Fujii; Susumu Iiizumi; Noritaka Adachi, Jan. 2008, DNA AND CELL BIOLOGY, 27, 1, 55, 61, Scientific journal

  DOI
• Highly proficient gene targeting by homologous recombination in the human Pre-B cell line Nalm-6, Noritaka Adachi; Aya Kurosawa; Hideki Koyama, 2008, Methods in Molecular Biology, 435, 17, 29, Scientific journal

  DOI
• Overexpression of HAM1 gene detoxifies 5-bromodeoxyuridine in the yeast Saccharomyces cerevisiae, Shinichi Takayama; Michihiko Fujii; Aya Kurosawa; Noritaka Adachi; Dai Ayusawa, Nov. 2007, CURRENT GENETICS, 52, 5-6, 203, 211, Scientific journal

  DOI
• Human neutrophils isolated from peripheral blood contain Ku protein but not DNA-dependent protein kinase, A Kurosawa; K Shinohara; F Watanabe; K Shimizu-Saito; O Koiwai; K Yamamoto; H Teraoka, Jan. 2003, INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 35, 1, 86, 94, Scientific journal

  DOI

MISC

• 非相同末端連結とその阻害剤., 黒沢 綾; 足立 典隆, 2017, 52, 162, 172, Introduction scientific journal
• XRCC4遺伝子変異を原因とする遺伝性疾患：免疫不全を伴わない原発性小人症., 斎藤 慎太; 黒沢 綾; 足立 典隆, 2015, 50, 269, 280, Introduction scientific journal
• ヒト細胞におけるDNA二本鎖切断の修復., 黒沢 綾; 足立 典隆, 2014, 72, 8, 14, Introduction scientific journal
• Human DNA ligase IV and Artemis independently contribute to cytotoxicity in the presence of replication-associated DNA damage: implications for double-strand break repair, A. Kurosawa; N. Adachi, Jun. 2008, FEBS JOURNAL, 275, 114, 114, Summary international conference
• ヒト重症複合型免疫不全症候群原因遺伝子ARTEMISの機能と制御．, 黒沢 綾; 足立 典隆, 2007, 42, 386, 401, Introduction scientific journal
• DNA二重鎖切断修復の新守護神．, 黒沢 綾; 足立 典隆, 2006, 24, 1304, 1305, Introduction commerce magazine

Books etc

• 進化するゲノム編集技術., Contributor, 2015
• Gatewayを用いた遺伝子導入マニュアル., Contributor, 2009
• 染色体サイクル., Contributor, 2009

Presentations

• ケルセチンによるDNA二本鎖切断誘発とその修復の機構の解析, 黒沢 綾、染谷 柚月、斎藤 慎太、武田 茂樹、足立 典隆, 第77回 日本酸化ストレス学会 第23回 日本NO学会 合同学術集会, 18 May 2024, 17 May 2024, 19 May 2024, Japanese, Domestic conference
• ゲニステインの細胞毒性機構の解析, 藤田 真尋, 染谷 柚月, 小林 咲音, 鳥海 一也, 武田 茂樹, 足立 典隆, 黒沢 綾, 日本環境変異原ゲノム学会第52回大会, 12 Nov. 2023, 11 Nov. 2023, 12 Nov. 2023, Domestic conference
• 食品由来フラボノイドケルセチンのDNA二本鎖切断誘発作用の解析, 染谷 柚月, 小林 咲音, 斎藤 慎太, 武田 茂樹, 足立 典隆, 黒沢 綾, 日本環境変異原ゲノム学会第52回大会, 11 Nov. 2023, 11 Nov. 2023, 12 Nov. 2023, Japan, Domestic conference
• 食品由来フラボノイドケルセチンのDNA二本鎖切断誘発作用の解析, 染谷柚月、小林咲音、斎藤慎太、武田茂樹、足立典隆、黒沢綾, 日本環境変異原ゲノム学会第51回大会, Nov. 2022, Nov. 2022, Japan, Domestic conference
• スルフォラファンの細胞毒性機構の解析, 小林咲音、染谷柚月、西場晟也、鳥海一也、武田茂樹、黒沢綾, 日本環境変異原ゲノム学会第51回大会, Nov. 2022, Japan
• 食品由来フラボノイドケルセチンのDNA二本鎖切断誘発作用, 染谷柚月; 鳥海一也; 武田茂樹; 足立典隆; 黒沢綾, 第75回日本酸化ストレス学会学術集会, May 2022, May 2022, Japanese, Domestic conference
• DNA損傷に着目したケルセチンによる抗腫瘍作用のメカニズムの解析, 染谷柚月; 鳥海一也; 武田茂樹; 黒沢綾;, 日本食品工学会第22回（2021年度）年次大会, Sep. 2021, Domestic conference
• Loss of DNA polymerase beta induces DNA double-strand breaks in neural progenitors of human iPSC-derived cerebral organoids, Sayaka Chiba; Kouki Masuta; Hiroto Tsunematsu; Aya Kurosawa; Noritaka Adachi; Nobuhiko Yamamoto; Takeshi Yagi; Noriyuki Sugo, 第44回日本神経科学大会CJK第1回国際会議, Jul. 2021, Domestic conference
• 抗酸化物質ケルセチンの放射線増感作用の分子機構の解析, 黒沢 綾; 鳥海 一也; 染谷 柚月; 武田 茂樹, 第74回 日本酸化ストレス学会 第21回 日本NO学会 合同学術集会, May 2021, Japanese, Domestic conference
• Impact of sulforaphane on genome integrity, Aya Kurosawa; Seiya Nishiba; Kazuya Toriumi; Shigeki Takeda; Noritaka Adachi, 20th Biennial Meeting of SFRR International, Mar. 2021, English, International conference
• Requirement of DNA double-strand break repair pathways for repairing high LET radiation- and radiomimetic agents-induced DNA damage., Aya Kurosawa; Akihisa Takahashi; Shigeki Takeda; Atsushi Shibata; Haruna Kamekawa; Noritaka Adachi, 日本放射線影響学会第63回大会, Oct. 2020, Japanese, Domestic conference
• ヒトDNAポリメラーゼβの機能解析, 松本由美; 黒沢 綾; 斎藤慎太; 足立典隆, 第42回日本分子生物学会年会, Dec. 2019
• Analysis of the cytotoxic mechanisms of sulforaphane, Seiya Nishiba; Shigeki Takeda; Noritaka Adachi; Aya Kurosawa, ICoFF2019/ICPH2019/SNFF2019, Dec. 2019, International conference
• Complex genetic interaction between DNA polymerase beta and the NHEJ ligase, Aya Kurosawa; Noritaka Adachi, ICRR2019, Aug. 2019, International conference
• Analysis of the cytotoxic mechanisms of sulforaphane, Seiya Nishiba; Shigeki Takeda; Kazuya Toriumi; Noritaka Adachi; Aya Kurosawa, The 41th Annual Meeting of the Molecular Biology Society of Japan, 30 Nov. 2018, Japanese, Domestic conference
• Identification of a novel proton sensing G protein-coupled receptor and its antagonists, Misaki Mashiko; Aya Kurosawa; M. Iwatsuki; T. Sunazuka; S. Omura; Shigeki Takeda, ConBio2017, Dec. 2017
• Analysis of antitumor mechanism of food-derived antioxidant agents, Kazuya Toriumi; Shigeki Takeda; Seiya Nishiba; Aya Kurosawa, ConBio2017, Dec. 2017
• Identification of a subtype specific inverse agonist for GPR173, Wataru Takano; Aya Kurosawa; Shigeki Takeda, 第39回日本分子生物学会年会, Dec. 2016
• Characterization of a novel agonist for the bile acid receptor, TGR5, Rina Enomoto; Yoshiaki Nikaido; Aya Kurosawa; Satoshi Kuroiwa; Yusuke Inoue; Michinari Otobe; Tamio Saito; Nobuto Kuwabara; Sezutsu Hideki; Mizuko Futahashi; Shigeki Takeda, 第39回日本分子生物学会年会, Dec. 2016
• Regulatory role of human DNA-PKcs in DNA double-strand break repair, Haruka Watabe; Shinta Saito; Aya Kurosawa; Noritaka Adachi, BMB2015, Dec. 2015
• Identification and appreciation of two novel antagonists of GPR173, Toshihiro Yanai; Aya Kurosawa; Tamio Saito; Shigeki Takeda, 第37回日本分子生物学会年会, 2014
• In vivo and in vitro evaluation of novel agonist compounds to the mu-opioid receptor, Hitomi Saikawa; Ryosuke Nikaido; Aya Kurosawa; Nobuo Kuwabara; Hajime Hoshino; Hideaki Obata; Shigeru Saito; Isao Kobayashi; Hideki Sezutsu; Shigeki Takeda, 第37回日本分子生物学会年会, 2014
• Roles of RAD54 and RAD54B in human somatic cell gene targeting, Shota Saito; Shinta Saito; Aya Kurosawa; Noritaka Adachi, 第37回日本分子生物学会, Nov. 2014
• Comprehensive analysis of random integration of transfected DNA in human cells, Aya Kurosawa; Ayako Ishii; Noritaka Adachi, 第36回日本分子生物学会, Dec. 2013
• Development of a high-efficiency gene-targeting system in human somatic cells, Shinta Saito; Natsumi Uchida; Miori Murayama; Aya Kurosawa; Noritaka Adachi, 第36回日本分子生物学会, Dec. 2013
• Genetic analysis of human nuclear sirtuins, Misaki Kawahara; Mikako Mori; Aya Kurosawa; Noritaka Adachi, 第36回日本分子生物学会, Dec. 2013
• Endogenous factors causative of spontaneous DNA damage that leads to random integration in human cells, Masumi Umehara; Aya Kurosawa; Haruna Kamekawa; Noritaka Adachi, 第36回日本分子生物学会, Dec. 2013
• Genetic analysis of human DNA-dependent protein kinase catalytic subunit, Haruka Watabe; Aya Kurosawa; Noritaka Adachi, 第36回日本分子生物学会, Dec. 2013
• Role of topoisomerase II in chromosomal DNA integration, Masumi Umehara; Aya Kurosawa; Mikako Mori; Shinta Saito; Noritaka Adachi, 第35回日本分子生物学会, Dec. 2012
• Functional analysis of Sirt1 in human cells, Mikako Mori; Aya Kurosawa; Noritaka Adachi, 第35回日本分子生物学会, Dec. 2012
• Establishment of a high-efficiency gene-trargeting system in human somatic cells and its application to quantitative analysis of targeted DNA integration, Shinta Saito; Miori Murayama; Natsumi Uchida; Aya Kurosawa; Noritaka Adachi, 第35回日本分子生物学会, Dec. 2012
• Role of human 53BP1 in DNA double-strand break repair, Shinta Saito; Aya Kurosawa; Noritaka Adachi, 第34回日本分子生物学会年会, Dec. 2011
• Analysis of the mechanism of foreign DNA integration in human cells, Aya Kurosawa; Ayako Ishii; Haruna Kamekawa; Shinta Saito; Mikako Mori; Noritaka Adachi, 第34回日本分子生物学会年会, Dec. 2011
• Impact of non-homologous end-joining-independent random integration, Ayako Ishii; Aya Kurosawa; Shinta Saito; Noritaka Adachi, BMB2010, Dec. 2010
• Impact of DNA topoisomerase II inhibition on random integration in human cells, Haruna Kamekawa; Aya Kurosawa; Noritaka Adachi, BMB2010, Dec. 2010
• Functional analysis of human 53BP1, Shinta Saito; Tadashi Matsui; Aya Kurosawa; Kuniyoshi Iwabuchi; Noritaka Adachi, BMB2010, Dec. 2010
• Role of Aprataxin in DNA strand break repair, Kana Ito; Aya Kurosawa; Noritaka Adachi, BMB2010, Dec. 2010
• Impact of RAG1 deficiency on gene targeting in human pre-B cells, Aya Kurosawa; Noritaka Adachi, BMB2010, Dec. 2010
• Improvement of gene-targeting efficiency in human cells, Aya Kurosawa; Noritaka Adachi, 第69回日本癌学会学術総会, Oct. 2010
• Impact of non-homologous end-joining deficiency on random and targeted DNA integration: Implications for gene targeting, Ayako Ishii; Aya Kurosawa; Susumu Iiizumi; Noritaka Adachi, 第32回日本分子生物学会年会, Dec. 2009
• ヒト細胞におけるDNA二本鎖切断修復の遺伝学的解析, Aya Kurosawa; Haruna Kamekawa; Noritaka Adachi, 第68回日本癌学会学術総会, Oct. 2009
• Generation and characterization of human Aprataxin knockout cells, 伊藤 佳奈; 飯泉 晋; 黒沢 綾; 足立 典隆, 日本人類遺伝学会 第54回大会, Sep. 2009
• ヒトNalm-6細胞を用いた遺伝子ノックアウト細胞の作製, 黒沢 綾; 足立 典隆, 日本人類遺伝学会 第54回大会, Sep. 2009
• ヒトNHEJ変異株における組換え頻度の解析, 石井 絢子; 黒沢 綾; 飯泉 晋; 足立 典隆, 日本薬学会 第129年会, Mar. 2009
• Independent roles of human Artemis and Ligase IV: Implications for DNA double-strand break repair, Aya Kurosawa; Noritaka Adachi, BMB2008, Dec. 2008
• Generation and characterization of human Aprataxin knockout cells, Kana Ito; Susumu Iiizumi; Aya Kurosawa; Noritaka Adachi, BMB2008, Dec. 2008
• Cell sorting analysis of cell cycle-dependent X-ray sensitivity in non-homologous end joining-deficient human cells, Mitsumasa Hashimoto; Tadashi Matsui; Aya Kurosawa; Noritaka Adachi; Takayasu Date; Kuniyoshi Iwabuchi, BMB2008, Dec. 2008
• Ligase IV-independent role of Artemis in DNA double-strand break repair, Aya Kurosawa; Noritaka Adachi, 67th Annual meeting of the Japan cancer association, Oct. 2008
• Bleomycin-induced DNA damage and repair in human cells, Haruna Kamekawa; Eriko Toyoda; Aya Kurosawa; Noritaka Adachi, 67th Annual meeting of the Japan cancer association, Oct. 2008
• Human DNA ligase IV and Artemis independently contribute to cytotoxicity in the presence of replication-associated DNA damage: Implications for double-strand break repair, Aya Kurosawa; Noritaka Adachi, 日本薬学会 第128年会, Mar. 2008
• Human DNA ligase IV and Artemis independently contribute to cytotoxicity in the presence of replication-associated DNA damage: Implications for double-strand break repair, Aya Kurosawa; Noritaka Adachi, 33rd FEBS Congress and 11th IUBMB Conference, Jun. 2008
• Impact of DSB repair deficiency in human cells: NHEJ negatively affects cell survival in the presence of replication-associated DNA damage, Aya Kurosawa; Sairei So; Hideki Koyama; Susumu Iiizumi; Noritaka Adachi, BMB2007, Dec. 2007
• Genetic studies on the repair of topoisomerase-mediated DNA damage using human gene knockout cell lines, Aya Kurosawa; Eriko Toyoda; Hideki Koyama; Noritaka Adachi, 66th Annual meeting of the Japan cancer association, Oct. 2007
• NK314 is a topoisomerase II alpha specific inhibitor forming stable DNA cleavage complex, 豊田 恵利子; 加々谷 重秀; 横山 浩史; 長幡 武光; 西川 清広; 黒沢 綾; 小山 秀機; 足立 典隆, 66th Annual meeting of the Japan cancer association, Oct. 2007
• Genetic studies on the repair of topoisomerase-mediated DNA damage using human gene knockout cell lines, Aya Kurosawa; Eriko Toyoda; Susumu Iiizumi; Sairei So; Hideki Koyama; Noritaka Adachi, EMBO Workshop 2007 DNA Supercoiling & Topoisomerases, Jun. 2007
• ヒト細胞におけるゲノム切断修復機構の解析, 足立 典隆; 黒沢 綾; 曽 彩玲; 飯泉 晋; 小山 秀機, 日本薬学会 第127年会, Mar. 2007
• Genetic analysis of human Artemis, Aya Kurosawa; Noritaka Adachi; Susumu Iiizumi; Yuji Nomura; Hideki Koyama, 日本分子生物学会2006フォーラム「分子生物学の未来」, Dec. 2006
• 遺伝子ノックアウトによるヒトDNA二本鎖切断修復機構の解析, 足立 典隆; 曽 彩玲; 飯泉 晋; 能村 悠司; 黒沢 綾; 植垣 幸一; 小山 秀機, 第28回日本分子生物学会年会, Dec. 2005
• NHEJの定量的assay系の確立とNHEJ機構の解明, 逆井 良; 吉岡 研一; 黒沢 綾; 市島 洋介; 小祝 修; 寺岡 弘文, 第75回日本生化学会大会, Dec. 2002
• DNA-PK欠損ヒトグリオーマ由来M059Jの細胞分子生物学的解析, 篠原 憲一; 逆井 良; 黒沢 綾; 渡邊 文晶; 水谷 修紀; 寺岡 弘文, 第25回日本分子生物学会年会, Dec. 2001
• DNAリガーゼIV活性制御における構造と調節因子の解析, 市島 洋介; 黒沢 綾; 行川 賢; 小祝 修; 坂口 謙吾; 寺岡 弘文, 第75回日本生化学会大会, Oct. 2002
• ヒト末梢好中球におけるKuとDNA-PK(p470)の挙動, 黒沢 綾; 篠原 憲一; 渡邊 文晶; 小祝 修; 山本 興太郎; 寺岡 弘文, 第24回日本分子生物学会年会, Dec. 2001
• DNAリガーゼIとDNAリガーゼVとの関連についての研究, 寺岡 弘文; 沖田 直之; 篠原 憲一; 黒沢 綾; 工藤 彩子; 岩成 宏子; 小林 進; 渡邊 文晶, 第74回日本生化学会大会, Oct. 2001
• 末梢好中球にもKu(p70/p86)は存在する, 黒沢 綾; 篠原 憲一; 渡邊 文晶; 小祝 修; 山本 興太郎; 寺岡 弘文, 日本細胞生物学会, Apr. 2001, Japanese, Domestic conference

Research Projects

• Apr. 2025, Mar. 2026, Principal investigator, Competitive research funding
• Apr. 2022, Mar. 2025, Principal investigator, Competitive research funding, No international co-authorship
• Oct. 2020, Mar. 2021, Principal investigator
• Sep. 2017, Aug. 2018, Principal investigator, Competitive research funding
• Apr. 2017, Mar. 2018, Principal investigator, Competitive research funding, No international co-authorship
• Apr. 2015, Mar. 2016, Principal investigator, Competitive research funding
• Apr. 2014, Mar. 2016, Principal investigator
• Jun. 2013, Mar. 2014, Principal investigator

Social Contribution

Social Contribution

• サイエンスカフェ in 桐生, 202, 10 Aug. 2024, 10 Aug. 2024