Researcher Profile and Settings

Researcher

• Name

  KOHNO Daisuke

Profile and Settings

• Name

  Kohno, Daisuke

Affiliation

• Gunma University, Institute for Molecular and Cellular Regulation Metabolic Signal Research Center, Assistant Professor
• Gunma University, Institute for Molecular and Cellular Regulation Metabolic Signal Research Center, Assistant Professor

Education

• Apr. 1997, Mar. 2001, Waseda University
• Apr. 2001, Mar. 2003, Waseda University, Graduate School of Science and Engineering
• Apr. 2003, Mar. 2007, Jichi Medical University

Degree

• PhD
• PhD
• PhD, Jichi Medical University

Research Experience

• Apr. 2007, Nov. 2007, Jichi Medical University, School of Medicine
• Dec. 2007, Aug. 2012
• Dec. 2009, Nov. 2011
• Sep. 2012, Mar. 2013, Jichi Medical University, School of Medicine
• Apr. 2013, Mar. 2018, Gunma University
• Apr. 2018, 9999, Gunma University, Institute for Molecular and Cellular Regulation

Research Activities

Research Areas

• Life sciences, Metabolism and endocrinology
• Life sciences, Molecular biology
• Life sciences, Physiology
• Life sciences, Clinical pharmacy

Research Interests

• NPY
• AgRP
• metabolism
• DNA methylation
• FTO
• m6A
• obesity
• hypothalamus
• feeding center
• epigenetics

Published Papers

• FTO promotes weight gain via altering Kif1a splicing and axonal vesicle trafficking in AgRP neurons., Kohno D, Kawabata-Iwakawa R, Ichinose S, Suyama S, Ohashi K, Ariyani W, Sadakata T, Yokota-Hashimoto H, Kobayashi R, Horii T, Susanti VY, Konno A, Tsuneoka H, Yoshikawa C, Matsui S, Harada A, Yada T, Hatada I, Hirai H, Nishiyama M, Sasaki T, Kitamura T., Sep. 2025, EMBO J, 44, 18, 4919, 4961, Scientific journal
• Dopaminergic neurons in the paraventricular hypothalamus extend the food consumption phase., Winda Ariyani; Chiharu Yoshikawa; Haruka Tsuneoka; Izuki Amano; Itaru Imayoshi; Hiroshi Ichinose; Chiho Sumi-Ichinose; Noriyuki Koibuchi; Tadahiro Kitamura; Daisuke Kohno, Apr. 2025, Proceedings of the National Academy of Sciences of the United States of America, 122, 13, e2411069122, Scientific journal

  DOI
• MOB1 deletion in murine mature adipocytes ameliorates obesity and diabetes., Miki Nishio; Keiko Yamaguchi; Junji Otani; Katsuya Yuguchi; Daisuke Kohno; Tsutomu Sasaki; Tadahiro Kitamura; Masakazu Shinohara; Tomoyoshi Soga; Koichi Kawamura; Atsuo T Sasaki; Masashi Oshima; Hiroki Hikasa; Minna Woo; Takehiko Sasaki; Hiroshi Nishina; Kazuwa Nakao; Tomohiko Maehama; Akira Suzuki, 29 Apr. 2025, Proceedings of the National Academy of Sciences of the United States of America, 122, 17, e2424741122, Scientific journal

  DOI
• Txnip deficiency causes a susceptibility to acute cold stress with brown fat dysfunction in mice., Meng Zou; Katsuya Tanabe; Kikuko Amo-Shiinoki; Daisuke Kohno; Syota Kagawa; Hideki Shirasawa; Kenji Ikeda; Akihiko Taguchi; Yasuharu Ohta; Shigeru Okuya; Tetsuya Yamada; Tadahiro Kitamura; Hiroshi Masutani; Yukio Tanizawa, 11 Feb. 2025, The Journal of biological chemistry, 301, 3, 108293, 108293, Scientific journal

  DOI
• DNA Methylation in the Hypothalamic Feeding Center and Obesity., Chiharu Yoshikawa; Winda Ariyani; Daisuke Kohno, 30 Dec. 2023, Journal of obesity & metabolic syndrome, 32, 4, 303, 311, Scientific journal

  DOI
• DNAメチル化修飾制御とDOHaD, 河野大輔, Mar. 2023, 11, 2, 109, 116

  DOI
• 【栄養・代謝物シグナルと食品機能　転写、エピゲノムの制御から代謝性疾患の治療・予防に向けて】(第3章)栄養・代謝物シグナル修飾および破綻と疾患　DNAメチル化修飾の栄養素・代謝物・肥満との関連と操作技術, ;;;;, May 2022, 40, 7, 1146
• Protein Kinase C (Pkc)-δ Mediates Arginine-Induced Glucagon Secretion in Pancreatic α-Cells, Norikiyo Honzawa; Kei Fujimoto; Masaki Kobayashi; Daisuke Kohno; Osamu Kikuchi; Hiromi Yokota-Hashimoto; Eri Wada; Yuichi Ikeuchi; Yoko Tabei; Gerald W. Dorn; Kazunori Utsunomiya; Rimei Nishimura; Tadahiro Kitamura, 04 Apr. 2022, International Journal of Molecular Sciences, 23, 7, 4003, 4003, Scientific journal

  DOI
• DNAメチル化修飾の栄養素・代謝物・肥満との関連と操作技術, 河野大輔、堀居拓郎、森田純代、常岡明加、畑田出穂, 2022, 40, 7, 1146, 1152
• The Hypothalamic Paraventricular Nucleus Is the Center of the Hypothalamic–Pituitary–Thyroid Axis for Regulating Thyroid Hormone Levels, Yuri Kondo; Atsushi Ozawa; Daisuke Kohno; Kazuma Saito; Battsetseg Buyandalai; Sayaka Yamada; Kazuhiko Horiguchi; Yasuyo Nakajima; Nobuyuki Shibusawa; Akihiro Harada; Hideaki Yokoo; Hideo Akiyama; Tsutomu Sasaki; Tadahiro Kitamura; Masanobu Yamada, 29 Dec. 2021, Thyroid, 32, 1, 105, 114, Scientific journal

  DOI
• Disordered branched chain amino acid catabolism in pancreatic islets is associated with postprandial hypersecretion of glucagon in diabetic mice, Eri Wada; Masaki Kobayashi; Daisuke Kohno; Osamu Kikuchi; Takayoshi Suga; Sho Matsui; Hiromi Yokota-Hashimoto; Norikiyo Honzawa; Yuichi Ikeuchi; Haruka Tsuneoka; Touko Hirano; Hideru Obinata; Tsutomu Sasaki; Tadahiro Kitamura, Nov. 2021, The Journal of Nutritional Biochemistry, 97, 108811, 108811, Scientific journal

  DOI
• Role of PDK1 in skeletal muscle hypertrophy induced by mechanical load., Naoki Kuramoto; Kazuhiro Nomura; Daisuke Kohno; Tadahiro Kitamura; Gerard Karsenty; Tetsuya Hosooka; Wataru Ogawa, 10 Feb. 2021, Scientific reports, 11, 1, 3447, 3447, Scientific journal

  DOI
• Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis., Hirotsugu Uzawa; Daisuke Kohno; Tomoaki Koga; Tsutomu Sasaki; Ayako Fukunaka; Toshiaki Okuno; Airi Jo-Watanabe; Saiko Kazuno; Takeshi Miyatsuka; Tadahiro Kitamura; Yoshio Fujitani; Hirotaka Watada; Kazuko Saeki; Takehiko Yokomizo, 26 Aug. 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34, 10, 13949, 13958, Scientific journal

  DOI
• Anagliptin suppresses diet-induced obesity through enhancing leptin sensitivity and ameliorating hyperphagia in high-fat high-sucrose diet fed mice., Kohno D, Furusawa K, Kitamura T., 28 May 2020, Endocr J, 67, 5, 523, 529, Scientific journal

  DOI
• Anagliptin suppresses diet-induced obesity through enhancing leptin sensitivity and ameliorating hyperphagia in high-fat high-sucrose diet fed mice., Daisuke Kohno; Kenichi Furusawa; Tadahiro Kitamura, 28 May 2020, Endocrine journal, 67, 5, 523, 529, Scientific journal

  DOI
• P110β in the ventromedial hypothalamus regulates glucose and energy metabolism., Teppei Fujikawa; Yun-Hee Choi; Dong Joo Yang; Dong Min Shin; Jose Donato Jr; Daisuke Kohno; Charlotte E Lee; Carol F Elias; Syann Lee; Ki Woo Kim, 26 Apr. 2019, Experimental & molecular medicine, 51, 4, 1, 9

  DOI
• SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels, Suga T; Kikuchi O; Kobayashi O; Matsui S; Yokota-Hashimoto H; Wada E; Kohno D; Sasaki T; Takeuchi K; Kakizaki S; Yamada M; Kitamura T, Jan. 2019, Mol Metab, 19:, 1, 12, Scientific journal

  DOI
• Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice., Sho Matsui; Tsutomu Sasaki; Daisuke Kohno; Keisuke Yaku; Ayumu Inutsuka; Hiromi Yokota-Hashimoto; Osamu Kikuchi; Takayoshi Suga; Masaki Kobayashi; Akihiro Yamanaka; Akihiro Harada; Takashi Nakagawa; Tatsushi Onaka; Tadahiro Kitamura, 02 Nov. 2018, Nature communications, 9, 1, 4604, 4604, Scientific journal

  DOI
• Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension., Fumiko Kawakami-Mori; Mitsuhiro Nishimoto; Latapati Reheman; Wakako Kawarazaki; Nobuhiro Ayuzawa; Kohei Ueda; Daigoro Hirohama; Daisuke Kohno; Shigeyoshi Oba; Tatsuo Shimosawa; Takeshi Marumo; Toshiro Fujita, 02 Nov. 2018, JCI insight, 3, 21, Scientific journal

  DOI
• Hepatic protein tyrosine phosphatase receptor gamma links obesity-induced inflammation to insulin resistance, Xavier Brenachot; Giorgio Ramadori; Rafael M. Ioris; Christelle Veyrat-Durebex; Jordi Altirriba; Ebru Aras; Sanda Ljubicic; Daisuke Kohno; Salvatore Fabbiano; Sophie Clement; Nicolas Goossens; Mirko Trajkovski; Sheila Harroch; Francesco Negro; Roberto Coppari, Nov. 2017, NATURE COMMUNICATIONS, 8, 1, 1820, Scientific journal

  DOI
• Sweet taste receptor in the hypothalamus: a potential new player in glucose sensing in the hypothalamus, Daisuke Kohno, Jul. 2017, JOURNAL OF PHYSIOLOGICAL SCIENCES, 67, 4, 459, 465

  DOI
• Sweet Taste Receptor Serves to Activate Glucose- and Leptin-Responsive Neurons in the Hypothalamic Arcuate Nucleus and Participates in Glucose Responsiveness, Daisuke Kohno; Miho Koike; Yuzo Ninomiya; Itaru Kojima; Tadahiro Kitamura; Toshihiko Yada, Nov. 2016, FRONTIERS IN NEUROSCIENCE, 10, 502, Scientific journal

  DOI
• Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis, Daisuke Kohno; Syann Lee; Matthew J. Harper; Ki Woo Kim; Hideyuki Sone; Tsutomu Sasaki; Tadahiro Kitamura; Guoping Fan; Joel K. Elmquist, Nov. 2014, JOURNAL OF NEUROSCIENCE, 34, 46, 15288, 15296, Scientific journal

  DOI
• Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis, Kevin W. Williams; Tiemin Liu; Xingxing Kong; Makoto Fukuda; Yingfeng Deng; Eric D. Berglund; Zhuo Deng; Yong Gao; Tianya Liu; Jong-Woo Sohn; Lin Jia; Teppei Fujikawa; Daisuke Kohno; Michael M. Scott; Syann Lee; Charlotte E. Lee; Kai Sun; Yongsheng Chang; Philipp E. Scherer; Joel K. Elmquist, Sep. 2014, CELL METABOLISM, 20, 3, 471, 482, Scientific journal

  DOI
• Insulin Activates Vagal Afferent Neurons Including those Innervating Pancreas via Insulin Cascade and Ca(2+) Influx: Its Dysfunction in IRS2-KO Mice with Hyperphagic Obesity., Yusaku Iwasaki; Kenju Shimomura; Daisuke Kohno; Katsuya Dezaki; Enkh-Amar Ayush; Hajime Nakabayashi; Naoto Kubota; Takashi Kadowaki; Masafumi Kakei; Masanori Nakata; Toshihiko Yada, 2013, PloS one, 8, 6, e67198, Scientific journal

  DOI
• Arcuate NPY neurons sense and integrate peripheral metabolic signals to control feeding, Daisuke Kohno; Toshihiko Yada, Dec. 2012, NEUROPEPTIDES, 46, 6, 315, 319

  DOI
• Neurohormones, Rikkunshito and Hypothalamic Neurons Interactively Control Appetite and Anorexia, Toshihiko Yada; Daisuke Kohno; Yuko Maejima; Udval Sedbazar; Takeshi Arai; Masako Toriya; Fumihiko Maekawa; Hedeharu Kurita; Akira Niijima; Koji Yakabi, Oct. 2012, CURRENT PHARMACEUTICAL DESIGN, 18, 31, 4854, 4864

  DOI
• FOXO1 in the ventromedial hypothalamus regulates energy balance, Ki Woo Kim; Jose Donato; Eric D. Berglund; Yun-Hee Choi; Daisuke Kohno; Carol F. Elias; Ronald A. DePinho; Joel K. Elmquist, Jul. 2012, JOURNAL OF CLINICAL INVESTIGATION, 122, 7, 2578, 2589, Scientific journal

  DOI
• Insulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleus, Yuko Maejima; Daisuke Kohno; Yusaku Iwasaki; Toshihiko Yada, Nov. 2011, AGING-US, 3, 11, 1092, 1097, Scientific journal
• Ghrelin Directly Stimulates Glucagon Secretion from Pancreatic alpha-Cells, Jen-Chieh Chuang; Ichiro Sakata; Daisuke Kohno; Mario Perello; Sherri Osborne-Lawrence; Joyce J. Repa; Jeffrey M. Zigman, Sep. 2011, MOLECULAR ENDOCRINOLOGY, 25, 9, 1600, 1611, Scientific journal

  DOI
• AMP-activated protein kinase activates neuropeptide Y neurons in the hypothalamic arcuate nucleus to increase food intake in rats, Daisuke Kohno; Hideyuki Sone; Shigeyasu Tanaka; Hideharu Kurita; Darambazar Gantulga; Toshihiko Yada, Jul. 2011, NEUROSCIENCE LETTERS, 499, 3, 194, 198, Scientific journal

  DOI
• Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus, Ki Woo Kim; Liping Zhao; Jose Donato; Daisuke Kohno; Yong Xu; Carol F. Elias; Charlotte Lee; Keith L. Parker; Joel K. Elmquist, Jun. 2011, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108, 26, 10673, 10678, Scientific journal

  DOI
• SF-1 in the ventral medial hypothalamic nucleus: A key regulator of homeostasis, Ki Woo Kim; Jong-Woo Sohn; Daisuke Kohno; Yong Xu; Kevin Williams; Joel K. Elmquist, Apr. 2011, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 336, 1-2, 219, 223, Scientific journal

  DOI
• Nesfatin-1-Regulated Oxytocinergic Signaling in the Paraventricular Nucleus Causes Anorexia through a Leptin-Independent Melanocortin Pathway, Yuko Maejima; Udval Sedbazar; Shigetomo Suyama; Daisuke Kohno; Tatsushi Onaka; Eisuke Takano; Natsu Yoshida; Masato Koike; Yasuo Uchiyama; Ken Fujiwara; Takashi Yashiro; Tamas L. Horvath; Marcelo O. Dietrich; Shigeyasu Tanaka; Katsuya Dezaki; Shinsuke Oh-I; Koushi Hashimoto; Hiroyuki Shimizu; Masanori Nakata; Masatomo Mori; Toshihiko Yada, Nov. 2009, CELL METABOLISM, 10, 5, 355, 365, Scientific journal

  DOI
• 5-HT(2C)Rs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis, Yong Xu; Juli E. Jones; Daisuke Kohno; Kevin W. Williams; Charlotte E. Lee; Michelle J. Choi; Jason G. Anderson; Lora K. Heisler; Jeffrey M. Zigman; Bradford B. Lowell; Joel K. Elmquist, Nov. 2008, NEURON, 60, 4, 582, 589, Scientific journal

  DOI
• Leptin transiently antagonizes ghrelin and long-lastingly orexin in regulation of Ca2+ signaling in neuropeptide Y neurons of the arcuate nucleus, Daisuke Kohno; Shigetomo Suyama; Toshihiko Yada, Nov. 2008, WORLD JOURNAL OF GASTROENTEROLOGY, 14, 41, 6347, 6354, Scientific journal

  DOI
• Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding, Daisuke Kohno; Masanori Nakata; Yuko Maejima; Hiroyuki Shimizu; Udval Sedbazar; Natsu Yoshida; Katsuya Dezaki; Tatsushi Onaka; Masatomo Mori; Toshihiko Yada, Mar. 2008, ENDOCRINOLOGY, 149, 3, 1295, 1301, Scientific journal

  DOI
• Ghrelin raises [Ca2+](i) via AMPK in hypothalamic arcuate nucleus NPY neurons, Daisuke Kohno; Hideyuki Sone; Yasuhiko Minokoshi; Toshihiko Yada, Feb. 2008, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 366, 2, 388, 392, Scientific journal

  DOI
• Synaptic interaction between ghrelin- and ghrelin-containing neurons in the rat hypothalamus, Yasunori Hori; Haruaki Kageyama; Jian-Lian Guan; Daisuke Kohno; Toshihiko Yada; Fumiko Takenoya; Naoko Nonaka; Kenji Kangawa; Seiji Shioda; Takemi Yoshida, Jan. 2008, REGULATORY PEPTIDES, 145, 1-3, 122, 127, Scientific journal

  DOI
• Leptin suppresses ghrelin-induced activation of neuropeptide y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway, Daisuke Kohno; Masanori Nakata; Fumihiko Maekawa; Ken Fujiwara; Yuko Maejima; Motoki Kuramochi; Takuya Shimazaki; Hideyuki Okano; Tatsushi Onaka; Toshihiko Yada, May 2007, ENDOCRINOLOGY, 148, 5, 2251, 2263, Scientific journal

  DOI
• Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK II phosphorylation in rats, Y. Oomura; N. Hori; T. Shiraishi; K. Fukunaga; H. Takeda; M. Tsuji; T. Matsurihiya; M. Ishibashi; S. Aou; X. L. Li; D. Kohno; K. Uramura; H. Sougawa; T. Yada; M. J. Wayner; K. Sasaki, Nov. 2006, PEPTIDES, 27, 11, 2738, 2749, Scientific journal

  DOI
• Young adult-specific hyperphagia in diabetic Goto-Kakizaki rats is associated with leptin resistance and elevation of neuropeptide Y mRNA in the arcuate nucleus, F. Maekawa; K. Fujiwara; D. Kohno; M. Kuramochi; H. Kurita; T. Yada, Oct. 2006, JOURNAL OF NEUROENDOCRINOLOGY, 18, 10, 748, 756, Scientific journal

  DOI
• Ghrelin and leptin reciprocally regulate NPY neurons in the arcuate nucleus, Daisuke Kohno; Masanori Nakata; Fumihiko Maekawa; Ken Fujiwara; Motoki Kuramochi; Takuya Shimazaki; Hideyuki Okano; Tatsushi Onaka; Toshihiko Yada, Aug. 2006, REGULATORY PEPTIDES, 135, 3, 136, 137, Scientific journal
• Galanin-like peptide stimulates food intake via activation of neuropeptide Y neurons in the hypothalamic dorsomedial nucleus of the rat, M Kuramochi; T Onaka; D Kohno; S Kato; T Yada, Apr. 2006, ENDOCRINOLOGY, 147, 4, 1744, 1752, Scientific journal

  DOI
• Galanin-like peptide and ghrelin increase cytosolic Ca2+ in neurons containing growth hormone-releasing hormone in the arcuate nucleus, M Kuramochi; D Kohno; T Onaka; S Kato; T Yada, Mar. 2005, REGULATORY PEPTIDES, 126, 1-2, 85, 89, Scientific journal

  DOI
• 【The Brain-Adipose Axis】基礎 The Brain-Adipose Axisの分子的基盤と生理的意義, 矢田 俊彦; 河野 大輔; 中田 正範, Dec. 2004, 1, 4, 361, 369
• PACAP deficient mice display reduced carbohydrate intake and PACAP activates NPY-containing neurons in the rat hypothalamic arcuate nucleus, M Nakata; D Kohno; N Shintani; Y Nemoto; H Hashimoto; A Baba; T Yada, Nov. 2004, NEUROSCIENCE LETTERS, 370, 2-3, 252, 256, Scientific journal

  DOI
• 摂食調節の神経機構 NPYニューロンにおける摂食調節因子の情報統合, 矢田 俊彦; 河野 大輔; 中田 正範, Sep. 2004, 10, Suppl., 101, 101
• Orexins (hypocretins) directly interact with neuropeptide YPOMC and glucose-responsive neurons to regulate Ca2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus, S Muroya; H Funahashi; A Yamanaka; D Kohno; K Uramura; T Nambu; M Shibahara; M Kuramochi; M Takigawa; M Yanagisawa; T Sakurai; S Shioda; T Yada, Mar. 2004, EUROPEAN JOURNAL OF NEUROSCIENCE, 19, 6, 1524, 1534, Scientific journal

  DOI
• Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus Ca2+ signalling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin, D Kohno; HZ Gao; S Muroya; S Kikuyama; T Yada, Apr. 2003, DIABETES, 52, 4, 948, 956, Scientific journal

  DOI
• PACAP activates PKA, PKC and Ca2+ signaling cascades in rat neuroepithelial cells, CJ Zhou; T Yada; D Kohno; S Kikuyama; R Suzuki; H Mizushima; S Shioda, Jul. 2001, PEPTIDES, 22, 7, 1111, 1117, Scientific journal

  DOI

MISC

• 膵α細胞における分岐鎖アミノ酸代謝異常は糖尿病のグルカゴン過剰分泌に関与する, 和田恵梨; 小林雅樹; 菊池司; 平野瞳子; 大日方英; 河野大輔; 北村忠弘, 2021, 97, 1
• AgRPニューロンのFTOによる体重調節機構, 河野大輔; 川端麗香; 常岡明加; 西山正彦; 佐々木努; 北村忠弘, 2021, 41st-38th (Web)
• 視床下部のFTOによるm⁶A脱メチル化を介した体重調節機構, 河野大輔; 常岡明加; 川端麗香; 西山正彦; 佐々木努; 北村忠弘, 2020, 34th
• 糖尿病病態での摂取栄養素に対するグルカゴン分泌応答異常の検証, 和田恵梨; 小林雅樹; 菊池司; 須賀孝慶; 松居翔; 河野大輔; 佐々木努; 竹内一翔; 串田祥; 北村忠弘, 2018, 61, Suppl
• SIRT1はショ糖摂食選択行動を制御する, 松居翔; 佐々木努; 河野大輔; 橋本博美; 小林雅樹; 北村忠弘, 2018, 2018

Presentations

• 視床下部室傍核ドーパミンニューロンの摂食の制御における役割, アリヤニ ウィンダ, 常岡 明加, 吉川 千遥, 天野, 出月, 鯉淵 典之, 一瀬 宏, 北村 忠弘, 河野 大輔, 第101回日本生理学会大会, 30 Mar. 2024
• AgRP ニューロンのFTOによるm6A修飾の脱メチル化を介した体重調節機構, 河野大輔, 第101回日本生理学会大会, 30 Mar. 2024
• 視床下部室傍核ドーパミンニューロンによる過食誘導機構の解明, 吉川 千遥; アリヤニ ウィンダ; 一瀬 宏; 北村 忠弘; 河野 大輔, 第44回日本肥満学会, 25 Nov. 2023
• AgRPニューロンのFTOによる体重制御機構, 河野大輔, 第44回日本肥満学会, 25 Nov. 2023
• 視床下部室傍核THニューロンの摂食行動と報酬系の制御における役割, アリヤニ ウィンダ; 常岡 明加; 吉川 千遥; 天野; 出月; 鯉淵 典之; 一瀬 宏; 北村 忠弘; 河野 大輔, 日本生理学会第100回記念大会, 15 Mar. 2023, 14 Mar. 2023, 16 Mar. 2023
• 視床下部室傍核ドーパミンニューロンの摂食行動における役割, アリヤニ ウィンダ; 常岡 明加; 吉川 千遥; 天野 出月; 鯉淵 典之; 一瀬 宏; 北村 忠弘; 河野 大輔, 第26回 アディポサイエンス・シンポジウム, 27 Jan. 2023
• 視床下部室傍核ドーパミンニューロンの摂食行動における役割, 河野 大輔; アリヤニ ウィンダ; 常岡 明加; 吉川 千遥; 一瀬 宏; 北村 忠弘, 第43回日本肥満学会, 03 Dec. 2022
• 視床下部室傍核ドーパミンニューロンの高脂肪食による影響と役割, 吉川千遥; アリヤニウィンダ; 常岡明加; 北村 忠弘; 河野大輔, 第9回⽇本DOHaD学会学術集会, 08 Oct. 2022
• 視床下部室傍核ドーパミンニューロンの 摂食行動における役割, 河野 大輔; アリヤニ ウィンダ; 常岡 明加; 吉川 千遥; 天野 出月; 一瀬 宏; 鯉淵 典之; 北村忠弘, 食欲・食嗜好研究会, 01 Oct. 2022
• The role of TH neurons in the PVH in the control of feeding behavior, Winda Ariyani; Haruka Tsuneoka; Chiharu Yoshikawa; Hiroshi Ichinose; Tadahiro Kitamura; Daisuke Kohno, 第45回日本神経科学大会 NEURO2022, 30 Jun. 2022
• AgRPニューロンのFTOによる体重調節機構, 河野 大輔; 川端 麗香; Winda Ariyani; 吉川 千遥; 常岡 明加; 佐々木 努; 北村 忠弘, 第42回日本肥満学会, 26 Mar. 2022
• 視床下部室傍核THニューロンの摂食行動調節における役割, ウィンダ アリヤニ; 常岡 明加; 吉川 千遥; 一瀬 宏; 北村 忠弘; 河野 大輔, 第99回日本生理学会大会, 17 Mar. 2022
• The role of TH neurons in the PVH in energy homeostasis, Tsuneoka H, Ichinose H, Kitamura H, Kohno H, 第43回日本神経科学大会, Jul. 2020
• 視床下部のFTOによるｍ6A脱メチル化を介した体重調節機構, 第34回⽇本糖尿病・肥満動物学会年次学術集会 2020年2月, Feb. 2020
• 視床下部のFTOによるｍ6A脱メチル化を介した体重調節機構, 第34回⽇本糖尿病・肥満動物学会年次学術集会, Feb. 2020
• 視床下部のFTOによる体重調節機構, 第40回⽇本肥満学会, Nov. 2019
• 視床下部摂食代謝中枢におけるDNAメチル化修飾の役割, 第37回内分泌代謝学サマーセミナー, Jul. 2019
• 視床下部のFTOによるm6A修飾を介した体重調節機構, 第39回日本肥満学会, Oct. 2018
• 視床下部におけるFTOとm6A修飾の役割, 第7回⽇本DOHaD学会学術集会, Aug. 2018
• FTOによるm6A修飾の制御と体重調節, 第12回日本エピジェネティクス研究会年会, May 2018
• 視床下部室傍核THニューロンの肥満発症における役割, 第38回日本肥満学会, Oct. 2017
• 視床下部室傍核THニューロンの肥満発症における役割, 第6回日本DOHaD学会学術集会, Aug. 2017
• 視床下部FTOによる体重調節機構, 第37回 日本肥満学会, Oct. 2016
• 視床下部FTOによる体重調節機構, 第5回 日本DOHaD研究会学術集会, Jul. 2016
• 視床下部摂食代謝中枢における甘味受容体の役割, 第93回 日本生理学会大会, Mar. 2016
• 視床下部室傍核ドーパミンニューロンの摂食行動における役割, 河野大輔, 第45回日本肥満学会, 19 Oct. 2024

Awards

• 2018
• 2017
• 2005
• 2006
• Dec. 2022

Research Projects

• The role of epigenome and epitranscriptome in the development of obesity, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Gunma University, Apr. 2021, Mar. 2025, 21H03349

  対象リソースIRI
• Jul. 2020, Mar. 2023, 20K21745

  対象リソースIRI
• Apr. 2017, Mar. 2020, Principal investigator, Competitive research funding
• Apr. 2015, Mar. 2017, Principal investigator, Competitive research funding
• Apr. 2013, Mar. 2015, Principal investigator, Competitive research funding
• Apr. 2013, Mar. 2015, Principal investigator, Competitive research funding
• 01 Apr. 2025, 31 Mar. 2030, 25K03043

  対象リソースIRI
• 28 Jun. 2024, 31 Mar. 2027, 24K22245

  対象リソースIRI