Researcher Profile and Settings

Researcher

• Name

  KAKIZAKI Toshikazu

Profile and Settings

• Name

  Kakizaki, Toshikazu

Foreign language

• Use in presentation

  English

• Use in publication

  English

Affiliation

• Gunma University, Assistant Professor
• Gunma University, Assistant Professor

Education

• Apr. 1997, Mar. 2001, Niigata University, Graduate School of Medicine
• Apr. 1995, Mar. 1997
• Apr. 1991, Mar. 1995, Niigata University, Faculty of Science, Department of Biology

Degree

• 条件付必須項目の入力がありません
• 条件付必須項目の入力がありません

Association Memberships

• International Society for Neurochemistry, Jan. 2020, 9999
• Society for Neuroscience, May 2011, 9999
• Feb. 2005, 9999

Research Experience

• May 2004, 9999, Assistant prof lv, Japan
• Apr. 2003, May 2004, Niigata University, Brain Research Institute, Researcher postdoc lv, Japan
• Jun. 2001, Mar. 2003, Niigata University, Brain Research Institute, Japan
• 2001, 2001, Niigata University, Brain Research Institute

Research Activities

Research Areas

• Life sciences, Neuroscience - general

Research Interests

• GABA
• glutamate decarboxylase

Published Papers

• Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats, Weiru Jiang, Toshikazu Kakizaki, Kazuyuki Fujihara, Shigeo Miyata, Yue Zhang, Takashi Suto, Daiki Kato, Shigeru Saito, Koji Shibasaki, Yasuki Ishizaki, Koji Isoda, Hideaki Yokoo, Hideru O, 31 Dec. 2021, FASEB Journal, 36, 2, e22123, Scientific journal
• Purkinje cell-specific and inducible gene recombination system generated from C57BL/6 mouse ES cells, K Kitayama; M Abe; T Kakizaki; D Honma; R Natsume; M Fukaya; M Watanabe; J Miyazaki; M Mishina; K Sakimura, 16 Mar. 2001, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 281, 5, 1134, 1140, Scientific journal

  DOI
• 脳発達時期に発現するNMDA受容体チャネルε2、ε4サブユニットの機能的差違, 柿崎 利和, 10 Oct. 2001, 115, 10, 518, 527, Doctoral thesis
• Differential palmitoylation of two mouse glutamate receptor interacting protein 1 forms with different N-terminal sequences, M Yamazaki; M Fukaya; M Abe; K Ikeno; T Kakizaki; M Watanabe; K Sakimura, 18 Mar. 2001, NEUROSCIENCE LETTERS, 304, 1-2, 81, 84, Scientific journal

  DOI
• NORADRENERGIC EXCITATION OF A SUBPOPULATION OF GABAergic CELLS IN THE BASOLATERAL AMYGDALA VIA BOTH ACTIVATION OF NONSELECTIVE CATIONIC CONDUCTANCE AND SUPPRESSION OF RESTING K+ CONDUCTANCE: A STUDY USING GLUTAMATE DECARBOXYLASE 67-GREEN FLUORESCENT PROTEIN KNOCK-IN MICE, K. Kaneko; N. Tamamaki; H. Owada; T. Kakizaki; N. Kume; M. Totsuka; T. Yamamoto; H. Yawo; T. Yagi; K. Obata; Y. Yanagawa, 10 Dec. 2008, NEUROSCIENCE, 157, 4, 781, 797, Scientific journal

  DOI
• GluR epsilon 2 subunit is crucial for NMDA receptor activity and regulation of postsynaptic macromolecular organization, Akashi Kaori; Kakizaki Toshikazu; Kamiya Haruyuki; Fukaya Masahiro; Yamasaki Miwako; Abe Manabu; Watanabe Masahiko; Sakimura Kenji, 2009, NEUROSCIENCE RESEARCH, 65, S139, S140

  DOI
• NMDA Receptor GluN2B (GluR epsilon 2/NR2B) Subunit Is Crucial for Channel Function, Postsynaptic Macromolecular Organization, and Actin Cytoskeleton at Hippocampal CA3 Synapses, Kaori Akashi; Toshikazu Kakizaki; Haruyuki Kamiya; Masahiro Fukaya; Miwako Yamasaki; Manabu Abe; Rie Natsume; Masahiko Watanabe; Kenji Sakimura, 02 Sep. 2009, JOURNAL OF NEUROSCIENCE, 29, 35, 10869, 10882, Scientific journal

  DOI
• FLUORESCENT LABELING OF BOTH GABAERGIC AND GLYCINERGIC NEURONS IN VESICULAR GABA TRANSPORTER (VGAT)-VENUS TRANSGENIC MOUSE, Y. Wang; T. Kakizaki; H. Sakagami; K. Saito; S. Ebihara; M. Kato; M. Hirabayashi; Y. Saito; N. Furuya; Y. Yanagawa, 15 Dec. 2009, NEUROSCIENCE, 164, 3, 1031, 1043, Scientific journal

  DOI
• LOW ACCUMULATION OF DREBRIN AT GLUTAMATERGIC POSTSYNAPTIC SITES ON GABAergic NEURONS, K. Hanamura; T. Mizui; T. Kakizaki; R. T. Roppongi; H. Yamazaki; Y. Yanagawa; T. Shirao, 15 Sep. 2010, NEUROSCIENCE, 169, 4, 1489, 1500, Scientific journal

  DOI
• The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice, Kenzi Saito; Toshikazu Kakizaki; Ryotaro Hayashi; Hiroshi Nishimaru; Tomonori Furukawa; Yoichi Nakazato; Shigeo Takamori; Satoe Ebihara; Masakazu Uematsu; Masayoshi Mishina; Jun-ichi Miyazaki; Minesuke Yokoyama; Shiro Konishi; Koichi Inoue; Atsuo Fukuda; Manabu Fukumoto; Kenji Nakamura; Kunihiko Obata; Yuchio Yanagawa, 30 Dec. 2010, MOLECULAR BRAIN, 3, Scientific journal

  DOI
• Motor dysfunction in cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice, Mikiko Kayakabe; Toshikazu Kakizaki; Ryosuke Kaneko; Atsushi Sasaki; Yoichi Nakazato; Koji Shibasaki; Yasuki Ishizaki; Hiromitsu Saito; Noboru Suzuki; Nobuhiko Furuya; Yuchio Yanagawa, 16 Jan. 2014, FRONTIERS IN CELLULAR NEUROSCIENCE, 7, 286, Scientific journal

  DOI
• GAD65/GAD67 DOUBLE KNOCKOUT MICE EXHIBIT INTERMEDIATE SEVERITY IN BOTH CLEFT PALATE AND OMPHALOCELE COMPARED WITH GAD67 KNOCKOUT AND VGAT KNOCKOUT MICE, T. Kakizaki; N. Oriuchi; Y. Yanagawa, 12 Mar. 2015, NEUROSCIENCE, 288, 86, 93, Scientific journal

  DOI
• Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes, Kazuyuki Fujihara; Hideki Miwa; Toshikazu Kakizaki; Ryosuke Kaneko; Masahiko Mikuni; Chiyoko Tanahira; Nobuaki Tamamaki; Yuchio Yanagawa, 23 Apr. 2015, NEUROPSYCHOPHARMACOLOGY, 40, 10, 2475, 2486, Scientific journal

  DOI
• A glycine transporter 2-Cre knock-in mouse line for glycinergic neuron-specific gene manipulation., Kakizaki T; Sakagami H; Sakimura K; Yanagawa Y, 08 Aug. 2017, IBRO Reports., 3, 9, 16, Scientific journal
• Loss of Glutamate Decarboxylase 67 in Somatostatin-Expressing Neurons Leads to Anxiety-Like Behavior and Alteration in the Akt/GSK3β Signaling Pathway., Miyata S; Kumagaya R; Kakizaki T; Fujihara K; Wakamatsu K; Yanagawa Y, 18 Jun. 2019, Frontiers in behavioral neuroscience, 13, 131, Scientific journal

  DOI
• Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons., Satomi Kikuta; Yoshio Iguchi; Toshikazu Kakizaki; Kazuto Kobayashi; Yuchio Yanagawa; Masahiko Takada; Makoto Osanai, 17 Dec. 2019, Frontiers in cellular neuroscience, 13, 547, 547, Scientific journal

  DOI
• Rats deficient in the GAD65 isoform exhibit epilepsy and premature lethality, Toshikazu Kakizaki; Tomokazu Ohshiro; Makoto Itakura; Kohtarou Konno; Masahiko Watanabe; Hajime Mushiake; Yuchio Yanagawa, 25 Nov. 2020, The FASEB Journal, 35, 2, Scientific journal

  DOI
• Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice, Miyata S, Kakizaki T, Fujihara K, Obinata H, Hirano T, Nakai J, Tanaka M, Itohara S, Watanabe M, Tanaka KF, Abe M, Sakimura K, Yanagawa Y., 07 Jan. 2021, Molecular Brain, 14, 1, Scientific journal

  DOI
• Decreased Lamin B1 Levels Affect Gene Positioning and Expression in Postmitotic Neurons., Noguchi A, Ito K, Uosaki Y, Ideta-Otsuka M, Igarashi K, Nakashima H, Kakizaki T, Kaneda R, Uosaki H, Yanagawa Y, Nakashima K, Arakawa H, Takizawa T., 28 May 2021, Neuroscience Research, 173, 22, 33, Scientific journal

  DOI
• Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons, Kikuta, Satomi;Iguchi, Yoshio;Kakizaki, Toshikazu;Kobayashi, Kazuto;Yanagawa, Yuchio;Takada, Masahiko;Osanai, Makoto, 2019, FRONTIERS IN CELLULAR NEUROSCIENCE, 13

  DOI
• Loss of Glutamate Decarboxylase 67 in Somatostatin-Expressing Neurons Leads to Anxiety-Like Behavior and Alteration in the Akt/GSK3 beta Signaling Pathway, Miyata, Shigeo;Kumagaya, Ryota;Kakizaki, Toshikazu;Fujihara, Kazuyuki;Wakamatsu, Kaori;Yanagawa, Yuchio, 2019, FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 13

  DOI
• ノックアウトラットによる2種類のGABA合成酵素アイソフォームの機能的役割の解明, ;;;;, Jun. 2021, 53, 7, 443
• The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice., Saito Kenzi;Kakizaki Toshikazu;Hayashi Ryotaro;Nishimaru Hiroshi;Furukawa Tomonori;Nakazato Yoichi;Takamori Shigeo;Ebihara Satoe;Uematsu Masakazu;Mishina Masayoshi;Miyazaki Jun-ichi;Yokoyama Minesuke;Konishi Shiro;Inoue Koichi;Fukuda Atsuo;Fukumoto Manabu;Nakamura Kenji;Obata Kunihiko;Yanagawa Yuchio, 30 Dec. 2010, Molecular brain, 3

  DOI
• Motor dysfunction in cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice., Kayakabe Mikiko;Kakizaki Toshikazu;Kaneko Ryosuke;Sasaki Atsushi;Nakazato Yoichi;Shibasaki Koji;Ishizaki Yasuki;Saito Hiromitsu;Suzuki Noboru;Furuya Nobuhiko;Yanagawa Yuchio, 16 Jan. 2014, Frontiers in cellular neuroscience, 7

  DOI
• Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes., Fujihara Kazuyuki;Miwa Hideki;Kakizaki Toshikazu;Kaneko Ryosuke;Mikuni Masahiko;Tanahira Chiyoko;Tamamaki Nobuaki;Yanagawa Yuchio, 23 Apr. 2015, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40, 10

  DOI
• A glycine transporter 2-Cre knock-in mouse line for glycinergic neuron-specific gene manipulation., Kakizaki Toshikazu;Sakagami Hiroyuki;Sakimura Kenji;Yanagawa Yuchio, 08 Aug. 2017, IBRO reports, 3

  DOI
• Loss of Glutamate Decarboxylase 67 in Somatostatin-Expressing Neurons Leads to Anxiety-Like Behavior and Alteration in the Akt/GSK3β Signaling Pathway., Miyata Shigeo;Kumagaya Ryota;Kakizaki Toshikazu;Fujihara Kazuyuki;Wakamatsu Kaori;Yanagawa Yuchio, 18 Jun. 2019, Frontiers in behavioral neuroscience, 13

  DOI
• Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons., Kikuta Satomi;Iguchi Yoshio;Kakizaki Toshikazu;Kobayashi Kazuto;Yanagawa Yuchio;Takada Masahiko;Osanai Makoto, 17 Dec. 2019, Frontiers in cellular neuroscience, 13

  DOI
• CRISPR/Cas9-engineered Gad1 elimination in rats leads to complex behavioral changes: implications for schizophrenia., Fujihara Kazuyuki;Yamada Kazuo;Ichitani Yukio;Kakizaki Toshikazu;Jiang Weiru;Miyata Shigeo;Suto Takashi;Kato Daiki;Saito Shigeru;Watanabe Masahiko;Kajita Yuki;Ohshiro Tomokazu;Mushiake Hajime;Miyasaka Yoshiki;Mashimo Tomoji;Yasuda Hiroki;Yanagawa Yuchio, 08 Dec. 2020, Translational psychiatry, 10, 1, Scientific journal

  DOI
• Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats., Jiang Weiru;Kakizaki Toshikazu;Fujihara Kazuyuki;Miyata Shigeo;Zhang Yue;Suto Takashi;Kato Daiki;Saito Shigeru;Shibasaki Koji;Ishizaki Yasuki;Isoda Koji;Yokoo Hideaki;Obinata Hideru;Hirano Touko;Miyasaka Yoshiki;Mashimo Tomoji;Yanagawa Yuchio, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36, 2

  DOI
• Glioma facilitates the epileptic and tumor-suppressive gene expressions in the surrounding region., Komiyama Kazuki;Iijima Keiya;Kawabata-Iwakawa Reika;Fujihara Kazuyuki;Kakizaki Toshikazu;Yanagawa Yuchio;Yoshimoto Yuhei;Miyata Shigeo, 26 Apr. 2022, Scientific reports, 12, 1, Scientific journal

  DOI
• The effects of a GlyT1 inhibitor on palatogenesis of GAD65/GAD67 double and VGAT knockout mice, Kakizaki, Toshikazu;Saito, Kenzi;Kayakabe, Mikiko;Yanagawa, Yuchio, 2010, NEUROSCIENCE RESEARCH, 68, E115, E115

  DOI
• Motor dysfunctions of striatal vesicular GABA transporter knockout mice, Saito, Kenzi;Kakizaki, Toshikazu;Kataoka, Hirotaka;Mishina, Masayoshi;Yanagawa, Yuchio, 2010, NEUROSCIENCE RESEARCH, 68, E145, E145

  DOI
• The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice, Saito, Kenzi;Kakizaki, Toshikazu;Hayashi, Ryotaro;Nishimaru, Hiroshi;Furukawa, Tomonori;Nakazato, Yoichi;Takamori, Shigeo;Ebihara, Satoe;Uematsu, Masakazu;Mishina, Masayoshi;Miyazaki, Jun-ichi;Yokoyama, Minesuke;Konishi, Shiro;Inoue, Koichi;Fukuda, Atsuo;Fukumoto, Manabu;Nakamura, Kenji;Obata, Kunihiko;Yanagawa, Yuchio, 2010, MOLECULAR BRAIN, 3

  DOI
• Generation and analysis of vesicular GABA transporter knockout mouse, Saito, Kenzi;Nakamura, Kenji;Kakizaki, Toshikazu;Ebihara, Satoe;Uematsu, Masakazu;Takamori, Shigeo;Yokoyama, Minesuke;Konishi, Shiro;Mishina, Masayoshi;Miyazaki, Jun-ichi;Obata, Kunihiko;Yanagawa, Yuchio, 2006, NEUROSCIENCE RESEARCH, 55, S80, S80
• The role of GABAergic system in ventral body wall formation, Kakizaki, Toshikazu;Saito, Kenzi;Yanagawa, Yuchio, 2006, NEUROSCIENCE RESEARCH, 55, S210, S210
• The role of inhibitory neurotransmission in ventral body wall formation, Kakizaki, Toshikazu;Kayakabe, Mikiko;Saito, Kenji;Yanagawa, Yuchio, 2007, NEUROSCIENCE RESEARCH, 58, S137, S137
• Altered motor function in vesicular GABA transporter knockout mice, Saito, Kenzi;Nishimaru, Hiroshi;Kakizaki, Toshikazu;Nakazato, Yoichi;Hayashi, Ryotaro;Fukumoto, Manabu;Yanagawa, Yuchio, 2007, NEUROSCIENCE RESEARCH, 58, S194, S194
• The roles of GABAergic and glycinergic neurotransmission systems during embryonic stages, Kakizaki, Toshikazu;Kayakabe, Mikiko;Saito, Kenzi;Yanagawa, Yuchio, 2008, NEUROSCIENCE RESEARCH, 61, S81, S81
• Motor dysfunction in neostriatal vesicular GABA transporter knock out mice, Saito, Kenzi;Kakizaki, Toshikazu;Momiyama, Toshihiko;Kataoka, Hirotaka;Mishina, Masayoshi;Yanagawa, Yuchio, 2008, NEUROSCIENCE RESEARCH, 61, S97, S97
• Transgenic expression of Venus fluorescent protein in inhibitory neurons, Wang, Ying;Kakizaki, Toshikazu;Saito, Kenzi;Ebihara, Satoe;Sakagami, Hiroyuki;Kato, Megumi;Hirabayashi, Masumi;Yanagawa, Yuchio, 2008, NEUROSCIENCE RESEARCH, 61, S137, S137
• NMDA Receptor GluN2B (GluR epsilon 2/NR2B) Subunit Is Crucial for Channel Function, Postsynaptic Macromolecular Organization, and Actin Cytoskeleton at Hippocampal CA3 Synapses, Akashi, Kaori;Kakizaki, Toshikazu;Kamiya, Haruyuki;Fukaya, Masahiro;Yamasaki, Miwako;Abe, Manabu;Natsume, Rie;Watanabe, Masahiko;Sakimura, Kenji, 2009, JOURNAL OF NEUROSCIENCE, 29, 35, 10869, 10882

  DOI
• The roles of GABAergic and glycinergic neurotransmissions in palate formation, Kakizaki, Toshikazu;Saito, Kenzi;Kayakabe, Mikiko;Yanagawa, Yuchio, 2009, NEUROSCIENCE RESEARCH, 65, S76, S76

  DOI
• GluR epsilon 2 subunit is crucial for NMDA receptor activity and regulation of postsynaptic macromolecular organization, Akashi, Kaori;Kakizaki, Toshikazu;Kamiya, Haruyuki;Fukaya, Masahiro;Yamasaki, Miwako;Abe, Manabu;Watanabe, Masahiko;Sakimura, Kenji, 2009, NEUROSCIENCE RESEARCH, 65, S139, S140

  DOI
• Generation and analysis of cerebellar Purkinje cell-specific VGAT knockout mice, Kakizaki, Toshikazu;Kayakabe, Mikiko;Kaneko, Ryosuke;Saito, Hiromitsu;Suzuki, Noboru;Yanagawa, Yuchio, 2011, NEUROSCIENCE RESEARCH, 71, E114, E114

  DOI
• Parvalbumin-positive neuron-specific GAD67 knockout mice exhibit schizophrenia-like phenotypes, Fujihara, Kazuyuki;Miwa, Hideki;Kakizaki, Toshikazu;Mikuni, Masahiko;Tanahira, Chiyoko;Tamamaki, Nobuaki;Yanagawa, Yuchio, 2011, NEUROSCIENCE RESEARCH, 71, E298, E298

  DOI
• The behavioral development in the GlyT2-deficient mice, Nishiyama, Ayae;Shimomura, Hideki;Kanbara-Kume, Nobuko;Kakizaki, Toshikazu;Tanizawa, Takakuni;Yanagawa, Yuchio;Arata, Akiko, 2013, JOURNAL OF PHYSIOLOGICAL SCIENCES, 63, S145, S145
• Motor dysfunction in cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice, Kayakabe, Mikiko;Kakizaki, Toshikazu;Kaneko, Ryosuke;Sasaki, Atsushi;Nakazato, Yoichi;Shibasaki, Koji;Ishizaki, Yasuki;Saito, Hiromitsu;Suzuki, Noboru;Furuya, Nobuhiko;Yanagawa, Yuchio, 2014, FRONTIERS IN CELLULAR NEUROSCIENCE, 7

  DOI
• Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes, Fujihara, Kazuyuki;Miwa, Hideki;Kakizaki, Toshikazu;Kaneko, Ryosuke;Mikuni, Masahiko;Tanahira, Chiyoko;Tamamaki, Nobuaki;Yanagawa, Yuchio, 2015, NEUROPSYCHOPHARMACOLOGY, 40, 10, 2475, 2486

  DOI

MISC

• The behavioral development in the GlyT2-deficient mice, Ayae Nishiyama; Hideki Shimomura; Nobuko Kanbara-Kume; Toshikazu Kakizaki; Takakuni Tanizawa; Yuchio Yanagawa; Akiko Arata, 2013, JOURNAL OF PHYSIOLOGICAL SCIENCES, 63, S145, S145, Summary international conference
• Parvalbumin-positive neuron-specific GAD67 knockout mice exhibit schizophrenia-like phenotypes, Kazuyuki Fujihara; Hideki Miwa; Toshikazu Kakizaki; Masahiko Mikuni; Chiyoko Tanahira; Nobuaki Tamamaki; Yuchio Yanagawa, 2011, NEUROSCIENCE RESEARCH, 71, E298, E298, Summary international conference

  DOI
• Generation and analysis of cerebellar Purkinje cell-specific VGAT knockout mice, Toshikazu Kakizaki; Mikiko Kayakabe; Ryosuke Kaneko; Hiromitsu Saito; Noboru Suzuki; Yuchio Yanagawa, 2011, NEUROSCIENCE RESEARCH, 71, E114, E114, Summary international conference

  DOI
• The effects of a GlyT1 inhibitor on palatogenesis of GAD65/GAD67 double and VGAT knockout mice, Toshikazu Kakizaki; Kenzi Saito; Mikiko Kayakabe; Yuchio Yanagawa, 2010, NEUROSCIENCE RESEARCH, 68, E115, E115, Summary international conference

  DOI
• Motor dysfunctions of striatal vesicular GABA transporter knockout mice, Kenzi Saito; Toshikazu Kakizaki; Hirotaka Kataoka; Masayoshi Mishina; Yuchio Yanagawa, 2010, NEUROSCIENCE RESEARCH, 68, E145, E145, Summary international conference

  DOI
• NMDA RECEPTOR GLUN2B SUBUNIT IS CRUCIAL FOR CHANNEL FUNCTION AND POST-SYNAPTIC MOLECULAR ORGANIZATION AT HIPPOCAMPAL CA3 SYNAPSES, K. Sakimura; K. Akashi; T. Kakizaki; H. Kamiya; M. Fukaya; M. Yamasaki; M. Abe; R. Natsume; M. Watanabe, Sep. 2009, JOURNAL OF NEUROCHEMISTRY, 110, 92, 92, Summary international conference
• The roles of GABAergic and glycinergic neurotransmissions in palate formation, Toshikazu Kakizaki; Kenzi Saito; Mikiko Kayakabe; Yuchio Yanagawa, 2009, NEUROSCIENCE RESEARCH, 65, S76, S76, Summary international conference

  DOI
• The roles of GABAergic and glycinergic neurotransmission systems during embryonic stages, Toshikazu Kakizaki; Mikiko Kayakabe; Kenzi Saito; Yuchio Yanagawa, 2008, NEUROSCIENCE RESEARCH, 61, S81, S81, Summary international conference
• Transgenic expression of Venus fluorescent protein in inhibitory neurons, Ying Wang; Toshikazu Kakizaki; Kenzi Saito; Satoe Ebihara; Hiroyuki Sakagami; Megumi Kato; Masumi Hirabayashi; Yuchio Yanagawa, 2008, NEUROSCIENCE RESEARCH, 61, S137, S137, Summary international conference
• Motor dysfunction in neostriatal vesicular GABA transporter knock out mice, Kenzi Saito; Toshikazu Kakizaki; Toshihiko Momiyama; Hirotaka Kataoka; Masayoshi Mishina; Yuchio Yanagawa, 2008, NEUROSCIENCE RESEARCH, 61, S97, S97, Summary international conference
• The role of inhibitory neurotransmission in ventral body wall formation, Toshikazu Kakizaki; Mikiko Kayakabe; Kenji Saito; Yuchio Yanagawa, 2007, NEUROSCIENCE RESEARCH, 58, S137, S137, Summary international conference
• Altered motor function in vesicular GABA transporter knockout mice, Kenzi Saito; Hiroshi Nishimaru; Toshikazu Kakizaki; Yoichi Nakazato; Ryotaro Hayashi; Manabu Fukumoto; Yuchio Yanagawa, 2007, NEUROSCIENCE RESEARCH, 58, S194, S194, Summary international conference
• The role of GABAergic system in ventral body wall formation, Toshikazu Kakizaki; Kenzi Saito; Yuchio Yanagawa, 2006, NEUROSCIENCE RESEARCH, 55, S210, S210, Summary international conference
• Generation and analysis of vesicular GABA transporter knockout mouse, Kenzi Saito; Kenji Nakamura; Toshikazu Kakizaki; Satoe Ebihara; Masakazu Uematsu; Shigeo Takamori; Minesuke Yokoyama; Shiro Konishi; Masayoshi Mishina; Jun-ichi Miyazaki; Kunihiko Obata; Yuchio Yanagawa, 2006, NEUROSCIENCE RESEARCH, 55, S80, S80, Summary international conference
• Effects of GluR beta 2/GluR6 disruption on the dynamics of other kainate receptor subunits, Kaori Akashi; Manabu Abe; Toshikazu Kakizaki; Rie Natsume; Kenji Sakimura, 2006, NEUROSCIENCE RESEARCH, 55, S82, S82, Summary international conference
• NMDA receptor GLUR epsilon 2/NR2B subunit is crucial for hippocampal synaptic functions, K Akashi; T Kakizaki; H Kamiya; M Fukaya; M Watanabe; K Sakimura, Aug. 2005, JOURNAL OF NEUROCHEMISTRY, 94, 59, 59, Summary international conference

Presentations

• Gad2ノックアウトラット脳におけるGAD67の細胞内局在, 柿崎利和、柳川右千夫, 第45回日本神経科学大会, 02 Jul. 2022, 30 Jun. 2022, 03 Jul. 2022, English, Japan, Domestic conference
• Behavioral analysis of GAD65 knockout rats, 柿崎利和、藤原和之、柳川右千夫, 第44回日本神経科学大会／CJK第1回国際会議, 31 Jul. 2021, 28 Jul. 2021, 31 Jul. 2021, English, International conference
• GAD65欠損ラットは脳内GABA含量の減少とてんかん重積状態を示す, 柿崎 利和; Weiru Jiang; 須藤 貴志; 齋藤 繁; 板倉 誠; 渡辺 雅彦; 柳川 右千夫, 第42回 日本神経科学大会, Jul. 2019
• Glutamate decarboxylase 65-deficient rats exhibit decreased brain GABA content and premature lethality, Toshikazu Kakizaki; Masahiko Watanabe; Yuchio Yanagawa, The 41st Annual Meeting of the Japan Neuroscience Society, Jul. 2018
• Decreased GABA content and premature lethality in glutamate decarboxylase 65-deficient rats, Toshikazu Kakizaki; Masahiko Watanabe; Yuchio Yanagawa, 11th FENS Forum of Neuroscience, Jul. 2018
• Premature lethality in glutamate decarboxylase 65-deficient rats, Toshikazu Kakizaki; Masahiko Watanabe; Yuchio Yanagawa, The 40th Annual Meeting of the Japan Neuroscience Society, Jul. 2017
• Phenotypic comparison between glutamate decarboxylase 65 knockout mice and rats, Toshikazu Kakizaki; Masahiko Watanabe; Yuchio Yanagawa, The 39th Annual Meeting of the Japan Neuroscience Society, 2016
• Comparison between glutamate decarboxylase 65 knockout mice and rats, T. Kakizaki; M. Watanabe; Y. Yanagawa, 10th FENS Forum of NEUROSCIENCE, 2016
• Generation and analysis of transgenic rodents expressing fluorescent proteins in inhibitory neurons, Neuro 2007 Satellite Symposium, 2007
• Altered motor function in vesicular GABA transporter knockout mice, 2007
• The role of inhibitory neurotransmission in ventral body wall formation, 2007
• NMDA receptor GluN2B Subunit is Crucial for Channel Function, Postsynaptic Macromolecular Organization, and Regulation of Actin Cytoskeleton at Hippocampal CA3 Synapses, 2010
• Cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice., 41st Annual Meeting of the Society for Neuroscience, 2011
• Analysis of cerebellar Purkinje cell-specific vesicular GABA transporter deficient mice., 4th International Symposium of the Society for Research on the Cerebellum, 2011
• Glycine transporter 2-Cre knock-in mice., 42nd Annual Meeting of the Society for Neuroscience, 2012
• Altered gene expressions and behavioral phenotypes of parvalbumin neuron-specific glutamate decarboxylase 67(GAD67) knockout mice., 42nd Annual Meeting of the Society for Neuroscience, 2012
• Localization of the Cre activity in the glycine transporter 2-Cre mice., 43rd Annual Meeting of the Society for Neuroscience, 2013
• Characterization of gene expression in mice lacking glutamate decarboxylase 67 primarily in parvalbumin neurons., 9th FENS Forum of NEUROSCIENCE, 2014
• 小胞型GABAトランスポーターノックアウトマウスの作成と解析, 第２９回 日本神経科学大会, 2006
• 腹側体壁形成におけるGABA作動性伝達系の役割, 第２９回 日本神経科学大会, 2006
• 脳発達時期に発現するNMDA受容体チャネルGluRepsilon2、GluRepsilon4サブユニットの機能的差違, 第２８回日本神経科学大会, 2005
• NMDA受容体GluRepsilon2サブユニットは機能的な海馬シナプス応答に必須である NMDA receptor GluRepsilon2 subunit is crucial for hippocampal synaptic function, 第34回米国神経科学会, 2004
• Generation and analysis of transgenic rodents expressing fluorescent proteins in inhibitory neurons, Neuro 2007 Satellite Symposium, 2007
• Altered motor function in vesicular GABA transporter knockout mice, 第３０回 日本神経科学大会, 2007
• The role of inhibitory neurotransmission in ventral body wall formation, 第３０回 日本神経科学大会, 2007
• 胎生期におけるGABAおよびグリシン作動性神経伝達系の役割, 第３１回日本神経科学大会, 2008
• 線条体小胞型GABAトランスポーター欠損による運動失調, 第３１回日本神経科学大会, 2008
• 抑制性ニューロンにVenus蛍光タンパク質を発現させたトランスジェニックマウス, 第３１回日本神経科学大会, 2008
• 口蓋形成におけるGABAおよびグリシン作動性神経伝達系の役割, 第３２回日本神経科学大会, 2009
• NMDA受容体GluRepsilon2サブユニットはNMDA受容体活性に必須な分子であり、かつシナプス後肥厚の分子複合体の形成維持に関与する, 第３２回日本神経科学大会, 2009
• NMDA receptor GluN2B Subunit is Crucial for Channel Function, Postsynaptic Macromolecular Organization, and Regulation of Actin Cytoskeleton at Hippocampal CA3 Synapses, 2010
• GAD65/GAD67ダブルおよびVGATノックアウトマウスの口蓋形成におけるGlyT1阻害剤の影響, 第５３回 日本神経科学大会, 2010
• 線条体VGAT欠損マウスの運動異常, 第５３回 日本神経科学大会, 2010
• Cerebellar Purkinje cell-specific vesicular GABA transporter knockout mice., 41st Annual Meeting of the Society for Neuroscience, 2011
• 小脳プルキンエ細胞特異的VGATノックアウトマウスの作製と解析, 2011
• パルブアルブミン陽性ニューロン特異的GAD67ノックアウトマウスは統合失調症様の表現型を示す, 第34回日本神経科学大会, 2011
• パルブアルブミンニューロン特異的GAD67ノックアウトマウスの大脳皮質におけるGAD65とパルブアルブミンの発現変化, 第35回日本神経科学大会, 2012
• Glycine transporter 2-Cre knock-in mice., 42nd Annual Meeting of the Society for Neuroscience, 2012
• パルブアルブミン陽性ニューロン特異的GAD67ノックアウトマウスを用いた統合失調症GABA仮説の検証, 第35回日本神経科学大会, 2012
• GLYT2-Creノックインマウスの作製と解析, 第35回日本神経科学大会, 2012
• GlyT2欠損マウスの新生仔期における行動発達, 第90回日本生理学会大会, 2013
• グリシントランスポーター2-Creノックインマウス系統の解析, 第36回日本神経科学大会, 2013
• Altered gene expressions and behavioral phenotypes of parvalbumin neuron-specific glutamate decarboxylase 67(GAD67) knockout mice., 42nd Annual Meeting of the Society for Neuroscience, 2012
• Analysis of cerebellar Purkinje cell-specific vesicular GABA transporter deficient mice., 4th International Symposium of the Society for Research on the Cerebellum, 2011
• Localization of the Cre activity in the glycine transporter 2-Cre mice., 43rd Annual Meeting of the Society for Neuroscience, 2013
• Characterization of gene expression in mice lacking glutamate decarboxylase 67 primarily in parvalbumin neurons., 9th FENS Forum of NEUROSCIENCE, 2014
• グリシントランスポーター2プロモーター駆動性Cre発現マウス系統におけるCre活性の組織学的解析, 第37回日本神経科学大会, 2014
• グリシン作動性ニューロンでCreを発現するマウス系統の開発, 第38回日本神経科学大会, 2015
• Generation of GAD65 knockout rats using TALEN-mediated genome editing., 第58回日本神経化学会大会, 2015

Research Grants & Projects

• 2005
• 201706, 201803
• 201806, 201903
• 2006
• 2009
• 2010
• 202102, 202103
• 20220401, 20250331

Social Contribution

Social Contribution

• 韓国建国大学トレーニングコース, Jan. 2007, Jan. 2007, Seminar　(Target:　College students)
• 群馬県立高崎高校2年生サイエンスクラス生命科学班スーパーサイエンスハイスクール, Nov. 2007, Nov. 2007, Seminar　(Target:　High school students)
• 世界脳週間2008, May 2008, May 2008, Seminar　(Target:　High school students, General)
• 韓国建国大学トレーニングコース, Jul. 2007, Jul. 2007, Seminar　(Target:　College students)
• 群馬県立高崎高校2年生サイエンスクラス生命科学班スーパーサイエンスハイスクール, Oct. 2008, Oct. 2008, Seminar　(Target:　High school students)
• 世界脳週間2009, Apr. 2009, Apr. 2009, Seminar　(Target:　High school students, General)
• 群馬県立高崎高校2年生サイエンスクラス生命科学班スーパーサイエンスハイスクール, Oct. 2009, Oct. 2009, Seminar　(Target:　High school students)
• 世界脳週間2010, Apr. 2010, Apr. 2010, Seminar　(Target:　High school students, General)
• 群馬県立高崎高校2年生サイエンスクラス生命科学班スーパーサイエンスハイスクール, Dec. 2010, Dec. 2010, Seminar　(Target:　High school students)
• 世界脳週間2012, Apr. 2012, Apr. 2012, Seminar　(Target:　High school students, General)
• 群馬県立沼田高校サイエンス・パートナーシップ・プログラム, Aug. 2012, Aug. 2012, Seminar　(Target:　High school students)
• 世界脳週間2013, Apr. 2013, Apr. 2013, Seminar　(Target:　High school students, General)
• 世界脳週間2014, Apr. 2014, Apr. 2014, Seminar　(Target:　High school students, General)
• 世界脳週間2015, Apr. 2015, Apr. 2015, Seminar　(Target:　High school students, General)
• 世界脳週間2016, Apr. 2016, Apr. 2016, Seminar　(Target:　High school students, General)
• 世界脳週間2017, Apr. 2017, Apr. 2017, Seminar　(Target:　High school students, General)
• 世界脳週間2018, Apr. 2018, Apr. 2018, Seminar　(Target:　High school students, General)
• 世界脳週間2019, Jun. 2019, Jun. 2019, Seminar　(Target:　High school students, General)
• 世界脳週間2006, May 2006, May 2006, Seminar　(Target:　High school students, General)
• 世界脳週間2007, May 2007, May 2007, Seminar　(Target:　High school students, General)