Researcher Database
| SASAKI Taeko |  |
| Institute for Molecular and Cellular Regulation | |
| Assistant Professor | |
Last Updated :2025/03/26
Researcher Profile and Settings
Researcher
Name
SASAKI Taeko
Affiliation
Profile and Settings
Name
Sasaki, Taeko
Affiliation
Affiliation
Affiliation
Institute for Molecular and Cellular Regulation, Biomembrane Functional Field
Education
- Apr. 2013, Nov. 2017
- Apr. 2011, Mar. 2013, Nagoya University
- Apr. 2007, Mar. 2011, Nagoya University, School of Science, Department of Biological Science
Degree
Association Memberships
- Japanese Society of Cell Biology, Oct. 2020, 9999
- The Molecular Biology Society of Japan, Dec. 2011, 9999
- The Japanese Society of Mitochondrial Research and Medicine, Dec. 2011, 9999
Research Experience
- Jul. 2021, 9999, Gunma University, Institute for Molecular and Cellular Regulation, Assistant prof lv
- Apr. 2020, Jun. 2021, Gunma University, Institute for Molecular and Cellular Regulation
- Apr. 2018, Mar. 2020, Gunma University
- Dec. 2017, Mar. 2018, Gunma University, Institute for Molecular and Cellular Regulation
- Apr. 2014, Mar. 2016, Nagoya University, Graduate School of Science
Research Activities
Research Areas
Research Interests
Published Papers
- Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms, Shun Kato; Kohei Arasaki; Natsuki Tokutomi; Yuzuru Imai; Tsuyoshi Inoshita; Nobutaka Hattori; Taeko Sasaki; Miyuki Sato; Yuichi Wakana; Hiroki Inoue; Mitsuo Tagaya, 15 Nov. 2021, Journal of Cell Science, 134, 22, Scientific journal
- Degradation of paternal mitochondria via mitophagy, Taeko Sasaki; Miyuki Sato, Jun. 2021, Biochimica et Biophysica Acta (BBA) - General Subjects, 1865, 6, 129886, 129886, Scientific journal
- Live imaging reveals the dynamics and regulation of mitochondrial nucleoids during the cell cycle in Fucci2-HeLa cells, Taeko Sasaki; Yoshikatsu Sato; Tetsuya Higashiyama; Narie Sasaki, Dec. 2017, Scientific Reports, 7, 1, Scientific journal
- Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria, Masako Koyama; Taeko Sasaki; Narie Sasaki; Yoshiyuki Matsuura, Sep. 2017, Protein Science, 26, 9, 1870, 1877, Scientific journal
- Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn-On DNA Probes, Kakishi Uno; Taeko Sasaki; Nagisa Sugimoto; Hideto Ito; Taishi Nishihara; Shinya Hagihara; Tetsuya Higashiyama; Narie Sasaki; Yoshikatsu Sato; Kenichiro Itami, 17 Jan. 2017, Chemistry - An Asian Journal, 12, 2, 233, 238, Scientific journal
- ThePhysarum polycephalumGenome Reveals Extensive Use of Prokaryotic Two-Component and Metazoan-Type Tyrosine Kinase Signaling, Pauline Schaap; Israel Barrantes; Pat Minx; Narie Sasaki; Roger W. Anderson; Marianne Bénard; Kyle K. Biggar; Nicolas E. Buchler; Ralf Bundschuh; Xiao Chen; Catrina Fronick; Lucinda Fulton; Georg Golderer; Niels Jahn; Volker Knoop; Laura F. Landweber; Chrystelle Maric; Dennis Miller; Angelika A. Noegel; Rob Peace; Gérard Pierron; Taeko Sasaki; Mareike Schallenberg-Rüdinger; Michael Schleicher; Reema Singh; Thomas Spaller; Kenneth B. Storey; Takamasa Suzuki; Chad Tomlinson; John J. Tyson; Wesley C. Warren; Ernst R. Werner; Gabriele Werner-Felmayer; Richard K. Wilson; Thomas Winckler; Jonatha M. Gott; Gernot Glöckner; Wolfgang Marwan, Jan. 2016, Genome Biology and Evolution, 8, 1, 109, 125, Scientific journal
- Environment-Sensitive Fluorescent Probe: A Benzophosphole Oxide with an Electron-Donating Substituent, Eriko Yamaguchi; Chenguang Wang; Aiko Fukazawa; Masayasu Taki; Yoshikatsu Sato; Taeko Sasaki; Minako Ueda; Narie Sasaki; Tetsuya Higashiyama; Shigehiro Yamaguchi, 07 Apr. 2015, Angewandte Chemie International Edition, 54, 15, 4539, 4543, Scientific journal
- MARC-3, a membrane-associated ubiquitin ligase, is required for fast polyspermy block in Caenorhabditis elegans., Kawasaki Ichiro;Sugiura Kenta;Sasaki Taeko;Matsuda Noriyuki;Sato Miyuki;Sato Ken, Jan. 2024, Nature communications, 15, 1
- ALLO-1- and IKKE-1-dependent positive feedback mechanism promotes the initiation of paternal mitochondrial autophagy., Sasaki Taeko;Kushida Yasuharu;Norizuki Takuya;Kosako Hidetaka;Sato Ken;Sato Miyuki, Feb. 2024, Nature communications, 15, 1
Presentations
- 線虫における父性ミトコンドリア 選択的オートファジーの分子機構, 佐々木妙子、櫛田康晴、小迫英尊、佐藤健、佐藤美由紀, OsakaMito2023 Autumn, 24 Oct. 2023, 24 Oct. 2023, 24 Oct. 2023, Japanese
- Regulation of paternal mitochondria autophagy via ALLO-1 and IKKE-1 in Caenorhabditis elegans, Taeko Sasaki , Yasuharu Kushida , Hidetaka Kosako , Ken Sato , Miyuki Sato, The 18th International Symposium of the Institute Network for Biomedical Sciences, 13 Oct. 2023, 13 Oct. 2023, 14 Oct. 2023, English
- The underlying mechanism of selective elimination of paternal mitochondria in C. elegans, Taeko Sasaki, Yasuharu Kushida, Hidetaka Kosako, Ken Sato, Miyuki Sato, 線虫研究の未来を創る会, 17 Aug. 2023, 16 Aug. 2023, 17 Aug. 2023, Japanese
- The underlying mechanism of selective elimination of paternal mitochondria in C. elegans, Taeko Sasaki, Yasuharu Kushida, Hidetaka Kosako, Ken Sato, Miyuki Sato, 第45回日本分子生物学会年会, Nov. 2022, 27 Nov. 2022, 01 Dec. 2022, English, Japan, Domestic conference
- The mechanisms of selective elimination of paternal organelles regulated by the autophagy adopter ALLO-1 and IKKE-1 kinase in Caenorhabditis elegans, Taeko Sasaki, Yasuharu Kushida, Hidetaka Kosako, Ken Sato, Miyuki Sato, 第8回 生体調節研究所 内分泌代謝シンポジウム, Oct. 2022, 10 Oct. 2022, 11 Oct. 2022, English, International conference
- The autophagy adaptor ALLO-1 and IKKE-1 kinase regulate selective elimination of paternal organelles in C. elegans, Taeko Sasaki, Yasuharu Kushida, Hidetaka Kosako, Ken Sato, Miyuki Sato, 10th International Symposium on Autophagy, Oct. 2022, 23 Oct. 2022, 27 Oct. 2022, English, International conference
- 線虫における父性ミトコンドリア選択的分解の分子基盤, 佐々木 妙子; 櫛田 康晴; 小迫 英尊; 佐藤 健; 佐藤 美由紀, 第20回 日本ミトコンドリア学会 年会, 10 Dec. 2021, 09 Dec. 2021, 10 Dec. 2021, Japanese
- 線虫における父性ミトコンドリア選択的分解の分子機構, 佐々木 妙子; 櫛田 康晴; 佐藤 健; 佐藤 美由紀, 第7回生殖若手の会, Oct. 2020, Japanese
- The mechanism underlying selective elimination of paternal mitochondria in C. elegans, Sasaki T; Kushida Y; Sato K; Sato M, 日本細胞生物学会第72回年会, Jun. 2020, English
- The mechanism of selective elimination of paternal mitochondria via autophagy receptor ALLO-1, Sasaki T; Sato K; Sato M, 日本分子生物学会第42回年会, Dec. 2019, English
- Coordinated Regulation of Mitochondrial Nucleoid Segregation and Mitochondrial DNA Replication during the Cell Cycle, Sasaki T; Yamada K; Sato Y; Higashiyama T; Sasaki N, 第39回日本分子生物学会大会, Dec. 2016, English
- 細胞周期におけるミトコンドリア核様体の分裂とmtDNA複製, 佐々木妙子; 山田佳歩; 佐藤良勝; 東山哲也; 佐々木成江, ミトコンドリアサイエンスワークショップ2016, Jul. 2016, Japanese
- Regulation of mitochondrial DNA replication and segregation of mitochondrial nucleoid during the cell cycle, Sasaki T; Yamada K; Higashiyama T; Sasaki N, YoungMito 2015, Jul. 2015, English
- 細胞周期におけるミトコンドリア核様体の分裂, 佐々木妙子,山田佳歩,東山哲也,佐々木成江, 第67 回日本細胞生物学会大会, Jul. 2015, Japanese
- ヒト培養細胞におけるミトコンドリア核様体分配に関わる新規RCC1様タンパク質の解析, 佐々木妙子; 山田佳歩; 由比良子; 鈴木俊哉; 石原直忠; 石原玲子; 東山哲也; 佐々木成江, 日本ミトコンドリア学会第十二回年会, Dec. 2012, Japanese
Awards
Research Projects
- 01 Apr. 2022, 31 Mar. 2025, 22K15097
- 24 Apr. 2020, 31 Mar. 2023, 20J01777
- Analysis of maternal inheritance of mitochondrial DNA using developed organelle sorter system, SASAKI NARIE; MORIYAMA Yosuke; ITAMI Kenichirou; URAKAWA Naoki; NAKAMURA Satoru; SASAKI Taeko; TANAKA Yoriko, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Nagoya University, 01 Apr. 2015, 31 Mar. 2018, In many eukaryotes, mitochondrial DNA (mtDNA) is inherited maternally, which is called maternal inheritance. For maternal inheritance, selective digestion of mtDNA in paternal mitochondria is essential. However, it is unknown how mtDNA in paternal mitochondria is selectively digested by DNase after zygosis or fertilization. In this study, to identify DNase involved in maternal inheritance of mtDNA, we tried to fractionate paternal mitochondria which had no mtDNA from zygote of Physarum polycephalu using cell sorter. Since mitochondria were destroyed in the cell sorter, we couldn’t fractionate. Then, we performed proteome analysis of isolated mitodhondria from zygote by nanoLC-MS/MS. We identified nine DNases in isolated mitochondria from zygotes that had mitochondria without mtDNA., 15K14559
- 25 Apr. 2014, 31 Mar. 2016, 14J04552