Researcher Profile and Settings

Researcher

• Name

  MIYAUCHI Eiji

Profile and Settings

• Name

  Miyauchi, Eiji

Affiliation

• Gunma University, Institute for Molecular and Cellular Regulation

Research Activities

Published Papers

• Fatty acid overproduction by gut commensal microbiota exacerbates obesity, Takeuchi T, Kameyama K, Miyauchi E, Nakanishi Y, Kanaya T, Fujii T, Kato T, Sasaki T, Tachibana N, Negishi H, Matsui M, Ohno H., 07 Feb. 2023, Cell Metab, 35, 2, 361, 375, Scientific journal
• The impact of the gut microbiome on extra-intestinal autoimmune diseases., Eiji Miyauchi; Chikako Shimokawa; Alex Steimle; Mahesh S Desai; Hiroshi Ohno, 09 May 2022, Nature reviews. Immunology, Scientific journal

  DOI
• High-throughput identification and quantification of single bacterial cells in the microbiota., Jianshi Jin; Reiko Yamamoto; Tadashi Takeuchi; Guangwei Cui; Eiji Miyauchi; Nozomi Hojo; Koichi Ikuta; Hiroshi Ohno; Katsuyuki Shiroguchi, 22 Feb. 2022, Nature communications, 13, 1, 863, 863, Scientific journal

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• Analysis of colonic mucosa-associated microbiota using endoscopically collected lavage., Eiji Miyauchi; Takashi Taida; Masami Kawasumi; Toshifumi Ohkusa; Nobuhiro Sato; Hiroshi Ohno, 02 Feb. 2022, Scientific reports, 12, 1, 1758, 1758, Scientific journal

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• Dysbiotic human oral microbiota alters systemic metabolism via modulation of gut microbiota in germ-free mice., Kyoko Yamazaki; Eiji Miyauchi; Tamotsu Kato; Keisuke Sato; Wataru Suda; Takahiro Tsuzuno; Miki Yamada-Hara; Nobuo Sasaki; Hiroshi Ohno; Kazuhisa Yamazaki, 2022, Journal of oral microbiology, 14, 1, 2110194, 2110194, Scientific journal

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• Acetate differentially regulates IgA reactivity to commensal bacteria., Tadashi Takeuchi; Eiji Miyauchi; Takashi Kanaya; Tamotsu Kato; Yumiko Nakanishi; Takashi Watanabe; Toshimori Kitami; Takashi Taida; Takaharu Sasaki; Hiroki Negishi; Shu Shimamoto; Akinobu Matsuyama; Ikuo Kimura; Ifor R Williams; Osamu Ohara; Hiroshi Ohno, Jul. 2021, Nature, 595, 7868, 560, 564, Scientific journal

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• Oral Pathobiont-Induced Changes in Gut Microbiota Aggravate the Pathology of Nonalcoholic Fatty Liver Disease in Mice., Kyoko Yamazaki; Tamotsu Kato; Yuuri Tsuboi; Eiji Miyauchi; Wataru Suda; Keisuke Sato; Mayuka Nakajima; Mai Yokoji-Takeuchi; Miki Yamada-Hara; Takahiro Tsuzuno; Aoi Matsugishi; Naoki Takahashi; Koichi Tabeta; Nobuaki Miura; Shujiro Okuda; Jun Kikuchi; Hiroshi Ohno; Kazuhisa Yamazaki, 2021, Frontiers in immunology, 12, 766170, 766170, Scientific journal

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• Gut microorganisms act together to exacerbate inflammation in spinal cords., Eiji Miyauchi; Seok-Won Kim; Wataru Suda; Masami Kawasumi; Satoshi Onawa; Naoko Taguchi-Atarashi; Hidetoshi Morita; Todd D Taylor; Masahira Hattori; Hiroshi Ohno, Sep. 2020, Nature, 585, 7823, 102, 106, Scientific journal

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• Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intra-epithelial lymphocytes in the intestine., Yuanbo Zhu; Guangwei Cui; Eiji Miyauchi; Yuki Nakanishi; Hisa Mukohira; Akihiro Shimba; Shinya Abe; Shizue Tani-Ichi; Takahiro Hara; Hiroshi Nakase; Tsutomu Chiba; Atsuko Sehara-Fujisawa; Hiroshi Seno; Hiroshi Ohno; Koichi Ikuta, 08 May 2020, International immunology, 32, 5, 307, 319, Scientific journal

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• Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells., Mari Tenno; Alicia Yoke Wei Wong; Mika Ikegaya; Eiji Miyauchi; Wooseok Seo; Peter See; Tamotsu Kato; Takashi Taida; Michiko Ohno-Oishi; Hiroshi Ohno; Hideyuki Yoshida; Florent Ginhoux; Ichiro Taniuchi, Jan. 2020, Life science alliance, 3, 1, Scientific journal

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• Intestinal IgA as a modulator of the gut microbiota., Shinsaku Okai; Fumihito Usui; Misa Ohta; Hiroshi Mori; Ken Kurokawa; Satoshi Matsumoto; Tamotsu Kato; Eiji Miyauchi; Hiroshi Ohno; Reiko Shinkura, 03 Sep. 2017, Gut microbes, 8, 5, 486, 492, Scientific journal

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• High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice., Shinsaku Okai; Fumihito Usui; Shuhei Yokota; Yusaku Hori-I; Makoto Hasegawa; Toshinobu Nakamura; Manabu Kurosawa; Seiji Okada; Kazuya Yamamoto; Eri Nishiyama; Hiroshi Mori; Takuji Yamada; Ken Kurokawa; Satoshi Matsumoto; Masanobu Nanno; Tomoaki Naito; Yohei Watanabe; Tamotsu Kato; Eiji Miyauchi; Hiroshi Ohno; Reiko Shinkura, 04 Jul. 2016, Nature microbiology, 1, 9, 16103, 16103, Scientific journal

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• Corrigendum: Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis., Tomoyo Taniguchi; Eiji Miyauchi; Shota Nakamura; Makoto Hirai; Kazutomo Suzue; Takashi Imai; Takahiro Nomura; Tadashi Handa; Hiroko Okada; Chikako Shimokawa; Risa Onishi; Alex Olia; Jun Hirata; Haruyoshi Tomita; Hiroshi Ohno; Toshihiro Horii; Hajime Hisaeda, 07 Jan. 2016, Scientific reports, 6, 17248, 17248

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• Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis., Tomoyo Taniguchi; Eiji Miyauchi; Shota Nakamura; Makoto Hirai; Kazutomo Suzue; Takashi Imai; Takahiro Nomura; Tadashi Handa; Hiroko Okada; Chikako Shimokawa; Risa Onishi; Alex Olia; Jun Hirata; Haruyoshi Tomita; Hiroshi Ohno; Toshihiro Horii; Hajime Hisaeda, 27 Oct. 2015, Scientific reports, 5, 15699, 15699, Scientific journal

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• Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells., Yukihiro Furusawa; Yuuki Obata; Shinji Fukuda; Takaho A Endo; Gaku Nakato; Daisuke Takahashi; Yumiko Nakanishi; Chikako Uetake; Keiko Kato; Tamotsu Kato; Masumi Takahashi; Noriko N Fukuda; Shinnosuke Murakami; Eiji Miyauchi; Shingo Hino; Koji Atarashi; Satoshi Onawa; Yumiko Fujimura; Trevor Lockett; Julie M Clarke; David L Topping; Masaru Tomita; Shohei Hori; Osamu Ohara; Tatsuya Morita; Haruhiko Koseki; Jun Kikuchi; Kenya Honda; Koji Hase; Hiroshi Ohno, 19 Dec. 2013, Nature, 504, 7480, 446, 50, Scientific journal

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• Bifidobacterium longum alleviates dextran sulfate sodium-induced colitis by suppressing IL-17A response: involvement of intestinal epithelial costimulatory molecules., Eiji Miyauchi; Tasuku Ogita; Junki Miyamoto; Seiji Kawamoto; Hidetoshi Morita; Hiroshi Ohno; Takuya Suzuki; Soichi Tanabe, 2013, PloS one, 8, 11, e79735, Scientific journal

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• Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production., Eiji Miyauchi; John O'Callaghan; Ludovica F Buttó; Gráinne Hurley; Silvia Melgar; Soichi Tanabe; Fergus Shanahan; Kenneth Nally; Paul W O'Toole, 01 Nov. 2012, American journal of physiology. Gastrointestinal and liver physiology, 303, 9, G1029-41, Scientific journal

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• Effect of D-alanine in teichoic acid from the Streptococcus thermophilus cell wall on the barrier-protection of intestinal epithelial cells., Eiji Miyauchi; Maho Morita; Mauro Rossi; Hidetoshi Morita; Takuya Suzuki; Soichi Tanabe, 2012, Bioscience, biotechnology, and biochemistry, 76, 2, 283, 8, Scientific journal
• Comparative Genomic Analysis of Lactococcus garvieae Strains Isolated from Different Sources Reveals Candidate Virulence Genes., Eiji Miyauchi; Hidehiro Toh; Akiyo Nakano; Soichi Tanabe; Hidetoshi Morita, 2012, International journal of microbiology, 2012, 728276, 728276, Scientific journal

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• Complete genome sequence and comparative analysis of the fish pathogen Lactococcus garvieae., Hidetoshi Morita; Hidehiro Toh; Kenshiro Oshima; Mariko Yoshizaki; Michiko Kawanishi; Kohei Nakaya; Takehito Suzuki; Eiji Miyauchi; Yasuo Ishii; Soichi Tanabe; Masaru Murakami; Masahira Hattori, 2011, PloS one, 6, 8, e23184, Scientific journal

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• Lactobacillus rhamnosus alleviates intestinal barrier dysfunction in part by increasing expression of zonula occludens-1 and myosin light-chain kinase in vivo, E. Miyauchi; H. Morita; S. Tanabe, Jun. 2009, Journal of Dairy Science, 92, 6, 2400, 2408, Scientific journal

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• Cell wall fraction of Enterococcus hirae ameliorates TNF-α-induced barrier impairment in the human epithelial tight junction, E. Miyauchi; H. Morita; J. Okuda; T. Sashihara; M. Shimizu; S. Tanabe, Apr. 2008, Letters in Applied Microbiology, 46, 4, 469, 476, Scientific journal

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• PCR method of detecting pork in foods for verifying allergen labeling and for identifying hidden pork ingredients in processed foods., Soichi Tanabe; Eiji Miyauchi; Akemi Muneshige; Kazuhiro Mio; Chikara Sato; Masahiko Sato, Jul. 2007, Bioscience, biotechnology, and biochemistry, 71, 7, 1663, 7, Scientific journal
• Identification of a peptide in enzymatic hydrolyzate of cheese that inhibits ovalbumin permeation in Caco-2 cells., Soichi Tanabe; Nana Isobe; Eiji Miyauchi; Shoko Kobayashi; Masayuki Suzuki; Munehiro Oda, 06 Sep. 2006, Journal of agricultural and food chemistry, 54, 18, 6904, 8, Scientific journal
• Genetic mutation in Escherichia coli genome during adaptation to the murine intestine is optimized for the host diet., Tsukimi Tomoya;Obana Nozomu;Shigemori Suguru;Arakawa Kazuharu;Miyauchi Eiji;Yang Jiayue;Song Isaiah;Ashino Yujin;Wakayama Masataka;Soga Tomoyoshi;Tomita Masaru;Ohno Hiroshi;Mori Hirotada;Fukuda Shinji, Jan. 2024, mSystems, 9, 2

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MISC

• 多発性硬化症の発症における腸内細菌の役割, 宮内栄治; 大野博司, 2022, 52, 1
• Multiple sclerosis and small intestinal microbiota., 宮内栄治; 大野博司, 2021, 月刊臨床免疫・アレルギー科, 75, 1
• Regulation of inflammatory responses in the central nervous system by gut microbiota, 宮内栄治, 2021, 腸内細菌学雑誌, 35, 2
• Autoimmune diseases and gut microbiota, 大野博司; 下川周子; 下川周子; 宮内栄治, 2021, 腸内細菌学雑誌, 35, 2
• 腸内細菌が中枢神経系炎症を悪化させる仕組みを解明 自己免疫疾患の難病・多発性硬化症の予防および治療法の開拓へ, 宮内栄治; 大野博司, 2021, 2021
• 脳とからだ I.腸,免疫系,脳の相互作用 腸内細菌と中枢神経系炎症, 宮内栄治; 大野博司, 2021, 72, 5
• Role of gut microbiota and immune system in multiple sclerosis, 宮内栄治; 大野博司, 2020, 月刊メディカル・サイエンス・ダイジェスト, 46, 4
• 常在細菌叢と生理・病理 IV.精神・神経系の制御,救急医療 18.多発性硬化症における腸内細菌の影響, 宮内栄治; 大野博司, 2019, 37, 2
• 腸管フローラと個別化医療 3 腸内細菌叢と腸管免疫, 宮内栄治; 大野博司, 2019, 2, 4
• マイクロバイオーム研究の最前線 多発性硬化症におけるマイクロバイオームの役割, 宮内栄治; 大野博司, 2018, 69, 3
• 腸内細菌と諸疾患-ここまで明らかになった腸内細菌と全身疾患の関連 腸内細菌と腸管免疫の相互作用, 宮内栄治; 大野博司, 2016, 34, 11
• 腸内細菌による多発性硬化症の制御, 宮内栄治, 2015, 253, 5
• 共生菌と免疫 ビフィズス菌によるTh17細胞の制御, 宮内栄治; 田辺創一; 大野博司, 2014, 62, 2
• 乳発酵食品の腸管への作用, 宮内栄治, 2010, 51, 4
• 乳酸菌・ビフィズス菌による腸管炎症抑制 細胞壁成分のリポテイコ酸がTLR2を介して腸管バリアを保護, 宮内栄治; 田辺創一, 2008, 46, 9

Social Contribution

Social Contribution

• 最先端生命科学セミナー, 11 Mar. 2023, 11 Mar. 2023

Academic Contribution

• 第２回腸内デザイン学会年会, Academic society etc, 15 Nov. 2022, 15 Nov. 2022