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OBINATA Hideru
Education and Research Support Center
Associate Professor
Last Updated :2025/03/27

Researcher Profile and Settings

Researcher

  • Name

    OBINATA Hideru

Profile and Settings

  • Name

    Obinata, Hideru

Foreign language

  • Use in presentation

    English

  • Use in publication

    English

Affiliation

  • Gunma University, Graduate School of Medicine Education and Research Support Center, Associate Professor

Education

  • 2000, The University of Tokyo
  • 1998, The University of Tokyo
  • 1996, The University of Tokyo, Faculty of Education

Degree

  • Doctor of philosophy

Research Experience

  • Apr. 2019, 9999, Gunma University, Graduate School of Medicine, Educational and Research Support Center, Associate Professor, Associate prof lecturer lv
  • Jan. 2016, Mar. 2019, Gunma University, Initiative for Advanced Research, Associate prof lecturer lv
  • Apr. 2015, Dec. 2015, Gunma University, Graduate School of Medicine, Associate prof lecturer lv
  • Aug. 2012, Mar. 2015, Others
  • Aug. 2009, Jul. 2012, Cornell University, Weill Medical College, Researcher postdoc lv
  • Jan. 2009, Jul. 2009, Researcher postdoc lv
  • Oct. 2000, Dec. 2008, Gunma University, Assistant prof lv

Research Activities

Research Areas

  • Life sciences, Medical biochemistry, lipid biochemistry

Published Papers

  • Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level., Tanaka Y,Konishi A,Obinata H,Tsuneoka M, Dec. 2019, Scientific reports, 9, 1, 18694
    DOI
  • Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice., Obinata H,Kuo A,Wada Y,Swendeman S,Liu CH,Blaho VA,Nagumo R,Satoh K,Izumi T,Hla T, Nov. 2019, Journal of lipid research, 60, 11, 1912, 1921
    DOI
  • Activation of the Sphingosine 1 Phosphate-Rho Pathway in Pterygium and in Ultraviolet-Irradiated Normal Conjunctiva., Nozomi Igarashi,Megumi Honjo,Takashi Fujishiro,Tetsuya Toyono,Takashi Ono,Yosai Mori,Kazunori Miyata,Hideru Obinata,Makoto Aihara, 20 Sep. 2019, International journal of molecular sciences, 20, 19
    DOI
  • Sphingosine 1-phosphate and inflammation., Obinata H,Hla T, Aug. 2019, International immunology, 31, 9, 617, 625
    DOI
  • Light Stress-Induced Increase of Sphingosine 1-Phosphate in Photoreceptors and Its Relevance to Retinal Degeneration., Terao R,Honjo M,Ueta T,Obinata H,Izumi T,Kurano M,Yatomi Y,Koso H,Watanabe S,Aihara M, Jul. 2019, International journal of molecular sciences, 20, 15
    DOI
  • Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure., Umbarawan Y,Syamsunarno MRAA,Koitabashi N,Obinata H,Yamaguchi A,Hanaoka H,Hishiki T,Hayakawa N,Sano M,Sunaga H,Matsui H,Tsushima Y,Suematsu M,Kurabayashi M,Iso T, Aug. 2018, Scientific reports, 8, 1, 12035
    DOI
  • Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice., Umbarawan Y,Syamsunarno MRAA,Koitabashi N,Yamaguchi A,Hanaoka H,Hishiki T,Nagahata-Naito Y,Obinata H,Sano M,Sunaga H,Matsui H,Tsushima Y,Suematsu M,Kurabayashi M,Iso T, Jul. 2018, Cardiovascular research, 114, 8, 1132, 1144
    DOI
  • Metabolic activity by F-18-FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC, Kyoichi Kaira,Tetsuya Higuchi,Ichiro Naruse,Yukiko Arisaka,Azusa Tokue,Bolag Altan,Satoshi Suda,Akira Mogi,Kimihiro Shimizu,Noriaki Sunaga,Takeshi Hisada,Shigehisa Kitano,Hideru Obinata,Takehiko Yokobori,Keita Mori,Masahiko Nishiyama,Yoshihito Tsushima,Takayuki Asao, Jan. 2018, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 45, 1, 56, 66, Scientific journal
    DOI
  • Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice, Yogi Umbarawan,Mas Rizky A. A. Syamsunarno,Hideru Obinata,Aiko Yamaguchi,Hiroaki Sunaga,Hiroki Matsui,Takako Hishiki,Tomomi Matsuura,Norimichi Koitabashi,Masaru Obokata,Hirofumi Hanaoka,Anwarul Haque,Fumio Kunimotol,Yoshito Tsushima,Makoto Suematsu,Masahiko Kurabayashi,Tatsuya Iso, Dec. 2017, METABOLISM-CLINICAL AND EXPERIMENTAL, 77, 47, 57, Scientific journal
    DOI
  • An engineered S1P chaperone attenuates hypertension and ischemic injury, Steven L. Swendeman,Yuquan Xiong,Anna Cantalupo,Hui Yuan,Nathalie Burg,Yu Hisano,Andreane Cartier,Catherine H. Liu,Eric Engelbrecht,Victoria Blaho,Yi Zhang,Keisuke Yanagida,Sylvain Galvani,Hideru Obinata,Jane E. Salmon,Teresa Sanchez,Annarita Di Lorenzo,Timothy Hla, Aug. 2017, SCIENCE SIGNALING, 10, 492, eaal2722, Scientific journal
    DOI
  • Enzymatic characterization of recombinant rat DDHD2: a soluble diacylglycerol lipase, Mari Araki,Noriyasu Ohshima,Chizu Aso,Akimitsu Konishi,Hideru Obinata,Kazuaki Tatei,Takashi Izumi, Nov. 2016, JOURNAL OF BIOCHEMISTRY, 160, 5, 269, 279, Scientific journal
    DOI
  • Protein purification and cloning of diacylglycerol lipase from rat brain, Chizu Aso,Mari Araki,Noriyasu Ohshima,Kazuaki Tatei,Tohko Hirano,Hideru Obinata,Mikiko Kishi,Koji Kishimoto,Akimitsu Konishi,Fumio Goto,Hiroyuki Sugimoto,Takashi Izumi, Jun. 2016, JOURNAL OF BIOCHEMISTRY, 159, 6, 585, 597, Scientific journal
    DOI
  • Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1, Pernille M. Christensen,Catherine H. Liu,Steven L. Swendeman,Hideru Obinata,Klaus Qvortrup,Lars B. Nielsen,Timothy Hla,Annarita Di Lorenzo,Christina Christoffersen, Jun. 2016, FASEB JOURNAL, 30, 6, 2351, 2359, Scientific journal
    DOI
  • Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure, Anna Cantalupo,Yi Zhang,Milankumar Kothiya,Sylvain Galvani,Hideru Obinata,Mariarosaria Bucci,Frank J. Giordano,Xian-Cheng Jiang,Timothy Hla,Annarita Di Lorenzo, Sep. 2015, NATURE MEDICINE, 21, 9, 1028, +, Scientific journal
    DOI
  • HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P(1) to limit vascular inflammation, Sylvain Galvani,Marie Sanson,Victoria A. Blaho,Steven L. Swendeman,Heather Conger,Bjorn Dahlback,Mari Kono,Richard L. Proia,Jonathan D. Smith,Timothy Hla, Aug. 2015, SCIENCE SIGNALING, 8, 389, ra79, Scientific journal
    DOI
  • Individual variation of human S1P(1) coding sequence leads to heterogeneity in receptor function and drug interactions, Hideru Obinata,Sarah Gutkind,Jeremiah Stitham,Toshiaki Okuno,Takehiko Yokomizo,John Hwa,Timothy Hla, Dec. 2014, JOURNAL OF LIPID RESEARCH, 55, 12, 2665, 2675, Scientific journal
    DOI
  • Flow-Regulated Endothelial S1P Receptor-1 Signaling Sustains Vascular Development, Bongnam Jung,Hideru Obinata,Sylvain Galvani,Karen Mendelson,Bi-sen Ding,Athanasia Skoura,Bernd Kinzel,Volker Brinkmann,Shahin Rafii,Todd Evans,Timothy Hla, Sep. 2012, DEVELOPMENTAL CELL, 23, 3, 600, 610, Scientific journal
    DOI
  • Fine-Tuning S1P Therapeutics, Hideru Obinata,Timothy Hla, Sep. 2012, CHEMISTRY & BIOLOGY, 19, 9, 1080, 1082
    DOI
  • Sphingosine 1-phosphate in coagulation and inflammation, Hideru Obinata,Timothy Hla, Jan. 2012, SEMINARS IN IMMUNOPATHOLOGY, 34, 1, 73, 91
    DOI
  • Assessment of sphingosine-1-phosphate activity in biological samples by receptor internalization and adherens junction formation., Obinata H,Hla T, 2012, Methods in molecular biology (Clifton, N.J.), 874, 69, 76
    DOI
  • Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M, Christina Christoffersen,Hideru Obinata,Sunil B. Kumaraswamy,Sylvain Galvani,Josefin Ahnstrom,Madhumati Sevvana,Claudia Egerer-Sieber,Yves A. Muller,Timothy Hla,Lars B. Nielsen,Bjorn Dahlback, Jun. 2011, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108, 23, 9613, 9618, Scientific journal
    DOI
  • Detection of G protein-coupled receptor-mediated cellular response involved in cytoskeletal rearrangement using surface plasmon resonance, Kexin Chen,Hideru Obinata,Takashi Izumi, Mar. 2010, BIOSENSORS & BIOELECTRONICS, 25, 7, 1675, 1680, Scientific journal
    DOI
  • Identification and Analysis of Two Splice Variants of Human G2A Generated by Alternative Splicing, Ai Ogawa,Hideru Obinata,Tomoyasu Hattori,Mikiko Kishi,Kazuaki Tatei,Osamu Ishikawa,Takashi Izumi, Feb. 2010, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 332, 2, 469, 478, Scientific journal
    DOI
  • G2A as a receptor for oxidized free fatty acids, Hideru Obinata,Takashi Izumi, Sep. 2009, PROSTAGLANDINS & OTHER LIPID MEDIATORS, 89, 3-4, 66, 72
    DOI
  • Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1., Tohko Hirano,Mikiko Kishi,Hiroyuki Sugimoto,Ryo Taguchi,Hideru Obinata,Noriyasu Ohshima,Kazuaki Tatei,Takashi Izumi, Aug. 2009, Biochimica et Biophysica Acta (Molecular and Cell Biology of Lipids), 1791, 8, 797, 805
    DOI
  • Ceramide Induces Myogenic Differentiation and Apoptosis in Drosophila Schneider Cells, Hidemasa Kawamura,Kazuaki Tatei,Tetsuo Nonaka,Hideru Obinata,Tomoyasu Hattori,Ai Ogawa,Hideko Kazama,Nobuyuki Hamada,Tomoo Funayama,Tetsuya Sakashita,Yasuhiko Kobayashi,Takashi Nakano,Takashi Izumi, Mar. 2009, JOURNAL OF RADIATION RESEARCH, 50, 2, 161, 169, Scientific journal
    DOI
  • Identification of novel peptide agonists from a random peptide library for a 5-oxo-ETE receptor, a receptor for bioactive lipids, Yoshinori Sasaki,Takashi Tsujii,Shigeki Takeda,Hideru Obinata,Takashi Izumi,Keiichi Yamada,Ryoichi Katakai, Dec. 2008, JOURNAL OF PEPTIDE SCIENCE, 14, 12, 1251, 1258, Scientific journal
    DOI
  • G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid, Tomoyasu Hattori,Hideru Obinata,Ai Ogawa,Mikiko Kishi,Kazuaki Tatei,Osamu Ishikawa,Takashi Izumi, May 2008, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 128, 5, 1123, 1133, Scientific journal
    DOI
  • [Progress in proton-sensitive GPCR research]., Obinata H,Izumi T, Feb. 2008, Seikagaku. The Journal of Japanese Biochemical Society, 80, 2, 113, 118
  • Morphine is an exogenous ligand for MrgX2, a G protein-coupled receptor for cortistatin, Natsuyo Akuzawa,Hideru Obinata,Takashi Izumi,Shigeki Takeda, 2008, Journal of Cell and Animal Biology
  • G2A as a receptor for oxidized free fatty acids., Hideru Obinata,Takashi Izumi, 2008, Prostaglandins and other lipid mediators
  • 5-oxo-eicosatetraenoic acid-induced chemotaxis: Identification of a responsible receptor hGPCR48 and negative regulation by G protein G(12/13), D Koike,H Obinata,A Yamamoto,S Takeda,H Komori,F Nara,T Izumi,T Haga, Mar. 2006, JOURNAL OF BIOCHEMISTRY, 139, 3, 543, 549, Scientific journal
    DOI
  • Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A., OBINATA HIDERU,HATTORI TOMOYASU,nakane shinji,TATEI KAZUAKI,IZUMI TAKASHI, Dec. 2005, J. Biol. Chem., 280, 49, 40676, 40683
    DOI
  • Glucocorticoids up-regulate leukotriene B-4 receptor-1 expression during neutrophilic differentiation of HL-60 cells, H Obinata,T Yokomizo,T Shimizu,T Izumi, Sep. 2003, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 309, 1, 114, 119, Scientific journal
    DOI
  • Identification of Ets-1 as an important transcriptional activator of CTP : phosphocholine cytidylyltransferase alpha in COS-7 cells and co-activation with transcriptional enhancer factor-4, H Sugimoto,S Sugimoto,K Tatei,H Obinata,M Bakovic,T Izumi,DE Vance, May 2003, JOURNAL OF BIOLOGICAL CHEMISTRY, 278, 22, 19716, 19722, Scientific journal
    DOI
  • Inhibition of protein kinases A and C demonstrates dual modes of response in human eosinophils stimulated with platelet-activating factor, T Takizawa,M Kato,H Kimura,M Suzuki,A Tachibana,H Obinata,T Izumi,K Tokuyama,A Morikawa, Aug. 2002, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 110, 2, 241, 248, Scientific journal
    DOI
  • Leukotriene receptors: classification, gene expression, and signal transduction., IZUMI TAKASHI,Yokomizo Takehiko,OBINATA HIDERU,Ogasawara Hideaki,Shimizu Takao, Jul. 2002, J. Biochem., 132, 1, 1, 6
    DOI
  • G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid, Hattori, Tomoyasu;Obinata, Hideru;Ogawa, Ai;Kishi, Mikiko;Tatei, Kazuaki;Ishikawa, Osamu;Izumi, Takashi, 2008, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 128, 5, 1123, 1133
    DOI
  • Identification of novel peptide agonists from a random peptide library for a 5-oxo-ETE receptor, a receptor for bioactive lipids, Sasaki, Yoshinori;Tsujii, Takashi;Takeda, Shigeki;Obinata, Hideru;Izumi, Takashi;Yamada, Keiichi;Katakai, Ryoichi, 2008, JOURNAL OF PEPTIDE SCIENCE, 14, 12, 1251, 1258
    DOI
  • Ceramide Induces Myogenic Differentiation and Apoptosis in Drosophila Schneider Cells, Kawamura, Hidemasa;Tatei, Kazuaki;Nonaka, Tetsuo;Obinata, Hideru;Hattori, Tomoyasu;Ogawa, Ai;Kazama, Hideko;Hamada, Nobuyuki;Funayama, Tomoo;Sakashita, Tetsuya;Kobayashi, Yasuhiko;Nakano, Takashi;Izumi, Takashi, 2009, JOURNAL OF RADIATION RESEARCH, 50, 2, 161, 169
    DOI
  • Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1, Hirano, Tbhko;Kishi, Mikiko;Sugimoto, Hiroyuki;Taguchi, Ryo;Obinata, Hideru;Ohshima, Noriyasu;Tatei, Kazuaki;Izumi, Takashi, 2009, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1791, 8, 797, 805
    DOI
  • Detection of G protein-coupled receptor-mediated cellular response involved in cytoskeletal rearrangement using surface plasmon resonance, Chen, Kexin;Obinata, Hideru;Izumi, Takashi, 2010, BIOSENSORS & BIOELECTRONICS, 25, 7, 1675, 1680
    DOI
  • Protein purification and cloning of diacylglycerol lipase from rat brain, Aso, Chizu;Araki, Mari;Ohshima, Noriyasu;Tatei, Kazuaki;Hirano, Tohko;Obinata, Hideru;Kishi, Mikiko;Kishimoto, Koji;Konishi, Akimitsu;Goto, Fumio;Sugimoto, Hiroyuki;Izumi, Takashi, 2016, JOURNAL OF BIOCHEMISTRY, 159, 6, 585, 597
    DOI
  • Enzymatic characterization of recombinant rat DDHD2: a soluble diacylglycerol lipase, Araki, Mari;Ohshima, Noriyasu;Aso, Chizu;Konishi, Akimitsu;Obinata, Hideru;Tatei, Kazuaki;Izumi, Takashi, 2016, JOURNAL OF BIOCHEMISTRY, 160, 5, 269, 279
    DOI
  • Metabolic activity by F-18-FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC, Kaira, Kyoichi;Higuchi, Tetsuya;Naruse, Ichiro;Arisaka, Yukiko;Tokue, Azusa;Altan, Bolag;Suda, Satoshi;Mogi, Akira;Shimizu, Kimihiro;Sunaga, Noriaki;Hisada, Takeshi;Kitano, Shigehisa;Obinata, Hideru;Yokobori, Takehiko;Mori, Keita;Nishiyama, Masahiko;Tsushima, Yoshihito;Asao, Takayuki, 2018, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 45, 1, 56, 66
    DOI
  • Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice, Umbarawan, Yogi;Syamsunarno, Mas Rizky A. A.;Obinata, Hideru;Yamaguchi, Aiko;Sunaga, Hiroaki;Matsui, Hiroki;Hishiki, Takako;Matsuura, Tomomi;Koitabashi, Norimichi;Obokata, Masaru;Hanaoka, Hirofumi;Haque, Anwarul;Kunimotol, Fumio;Tsushima, Yoshito;Suematsu, Makoto;Kurabayashi, Masahiko;Iso, Tatsuya, 2017, METABOLISM-CLINICAL AND EXPERIMENTAL, 77, 47, 57
    DOI
  • Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and-5 knockoutmice, Umbarawan, Yogi;Syamsunarno, Mas Rizky A. A.;Koitabashi, Norimichi;Yamaguchi, Aiko;Hanaoka, Hirofumi;Hishiki, Takako;Nagahata-Naito, Yoshiko;Obinata, Hideru;Sano, Motoaki;Sunaga, Hiroaki;Matsui, Hiroki;Tsushima, Yoshito;Suematsu, Makoto;Kurabayashi, Masahiko;Iso, Tatsuya, 2018, CARDIOVASCULAR RESEARCH, 114, 8, 1132, 1144
    DOI
  • Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure, Umbarawan, Yogi;Syamsunarno, Mas Rizky A. A.;Koitabashi, Norimichi;Obinata, Hideru;Yamaguchi, Aiko;Hanaoka, Hirofumi;Hishiki, Takako;Hayakawa, Noriyo;Sano, Motoaki;Sunaga, Hiroaki;Matsui, Hiroki;Tsushima, Yoshito;Suematsu, Makoto;Kurabayashi, Masahiko;Iso, Tatsuya, 2018, SCIENTIFIC REPORTS, 8
    DOI
  • Light Stress-Induced Increase of Sphingosine 1-Phosphate in Photoreceptors and Its Relevance to Retinal Degeneration, Terao, Ryo;Honjo, Megumi;Ueta, Takashi;Obinata, Hideru;Izumi, Takashi;Kurano, Makoto;Yatomi, Yutaka;Koso, Hideto;Watanabe, Sumiko;Aihara, Makoto, 2019, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20, 15
    DOI
  • Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice[S], Obinata, Hideru;Kuo, Andrew;Wada, Yukata;Swendeman, Steven;Liu, Catherine H.;Blaho, Victoria A.;Nagumo, Reiko;Sato, Kenichi;Izumi, Takashi;Hla, Timothy, 2019, JOURNAL OF LIPID RESEARCH, 60, 11, 1912, 1921
    DOI
  • Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level, Tanaka, Yuji;Konishi, Akimitsu;Obinata, Hideru;Tsuneoka, Makoto, 2019, SCIENTIFIC REPORTS, 9
    DOI
  • Leukotriene Receptors : Classification, Gene Expression, and Signal Transduction, IZUMI Takashi;YOKOMIZO Takehiko;OBINATA Hideru;OGASAWARA Hideaki;SHIMIZU Takao, Jul. 2002, The Journal of Biochemistry, 132, 1, 1, 6
  • ロイコトリエンB_4受容体のグルココルチコイドによる発現制御, 大日 方英;横溝 岳彦;清水 孝雄;和泉 孝志, May 2001, 43, 107, 109
  • 5-Oxo-Eicosatetraenoic Acid-Induced Chemotaxis : Identification of a Responsible Receptor hGPCR48 and Negative Regulation by G Protein G_<12/13>, KOIKE Daigo;OBINATA Hideru;YAMAMOTO Atsushi;TAKEDA Shigeki;KOMORI Hironobu;NARA Futoshi;IZUMI Takashi;HAGA Tatsuya, Mar. 2006, Journal of Biochemistry, 139, 3, 543, 549
  • Progress in proton-sensitive GPCR research, OBINATA Hideru;IZUMI Takashi, Feb. 2008, 80, 2, 113, 118
  • Ceramide Induces Myogenic Differentiation and Apoptosis in Drosophila Schneider Cells, KAWAMURA Hidemasa;TATEI Kazuaki;NONAKA Tetsuo;OBINATA Hideru;HATTORI Tomoyasu;OGAWA Ai;KAZAMA Hideko;HAMADA Nobuyuki;FUNAYAMA Tomoo;SAKASHITA Tetsuya;KOBAYASHI Yasuhiko;NAKANO Takashi;IZUMI Takashi, Mar. 2009, Journal of Radiation Research, 50, 2, 161, 169
  • Oxidized free fatty acids as lipid mediators and functions of G2A as their receptor, KISHIMOTO Koji;OBINATA Hideru;KISHI Mikiko;OHSHIMA Noriyasu;TATEI Kazuaki;IZUMI Takashi, Jun. 2011, 83, 6, 545, 554
  • Leukotriene receptors: classification, gene expression, and signal transduction., Izumi Takashi;Yokomizo Takehiko;Obinata Hideru;Ogasawara Hideaki;Shimizu Takao, Journal of biochemistry, 132, 1
    DOI
  • Inhibition of protein kinases A and C demonstrates dual modes of response in human eosinophils stimulated with platelet-activating factor., Takizawa Takumi;Kato Masahiko;Kimura Hirokazu;Suzuki Masato;Tachibana Atsushi;Obinata Hideru;Izumi Takashi;Tokuyama Kenichi;Morikawa Akihiro, The Journal of allergy and clinical immunology, 110, 2
    DOI
  • Identification of Ets-1 as an important transcriptional activator of CTP:phosphocholine cytidylyltransferase alpha in COS-7 cells and co-activation with transcriptional enhancer factor-4., Sugimoto Hiroyuki;Sugimoto Sayaka;Tatei Kazuaki;Obinata Hideru;Bakovic Marica;Izumi Takashi;Vance Dennis E, 17 Mar. 2003, The Journal of biological chemistry, 278, 22
    DOI
  • Glucocorticoids up-regulate leukotriene B4 receptor-1 expression during neutrophilic differentiation of HL-60 cells., Obinata Hideru;Yokomizo Takehiko;Shimizu Takao;Izumi Takashi, Biochemical and biophysical research communications, 309, 1
    DOI
  • Leukotriene Receptors: Classification, Gene Expression, and Signal Transduction., Izumi Takashi;Yokomizo Takehiko;Obinata Hideru;Ogasawara Hideaki;Shimizu Takao, 2002, J Biochem (Tokyo), 132, 1, 1, 6
  • Qualities of Lipids, Obinata Hideru, 2016, The Kitakanto Medical Journal, 66, 4, 293, 294
  • Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A., Obinata Hideru;Hattori Tomoyasu;Nakane Shinji;Tatei Kazuaki;Izumi Takashi, 19 Oct. 2005, The Journal of biological chemistry, 280, 49
    DOI
  • 5-Oxo-eicosatetraenoic acid-induced chemotaxis: identification of a responsible receptor hGPCR48 and negative regulation by G protein G(12/13)., Koike Daigo;Obinata Hideru;Yamamoto Atsushi;Takeda Shigeki;Komori Hironobu;Nara Futoshi;Izumi Takashi;Haga Tatsuya, Journal of biochemistry, 139, 3
    DOI
  • G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid., Hattori Tomoyasu;Obinata Hideru;Ogawa Ai;Kishi Mikiko;Tatei Kazuaki;Ishikawa Osamu;Izumi Takashi, 22 Nov. 2007, The Journal of investigative dermatology, 128, 5
    DOI
  • [Progress in proton-sensitive GPCR research]., Obinata Hideru;Izumi Takashi, Seikagaku. The Journal of Japanese Biochemical Society, 80, 2
  • Identification of novel peptide agonists from a random peptide library for a 5-oxo-ETE receptor, a receptor for bioactive lipids., Sasaki Yoshinori;Tsujii Takashi;Takeda Shigeki;Obinata Hideru;Izumi Takashi;Yamada Keiichi;Katakai Ryoichi, Journal of peptide science : an official publication of the European Peptide Society, 14, 12
    DOI
  • G2A as a receptor for oxidized free fatty acids., Obinata Hideru;Izumi Takashi, 21 Nov. 2008, Prostaglandins & other lipid mediators, 89, 3-4
    DOI
  • Ceramide induces myogenic differentiation and apoptosis in Drosophila Schneider cells., Kawamura Hidemasa;Tatei Kazuaki;Nonaka Tetsuo;Obinata Hideru;Hattori Tomoyasu;Ogawa Ai;Kazama Hideko;Hamada Nobuyuki;Funayama Tomoo;Sakashita Tetsuya;Kobayashi Yasuhiko;Nakano Takashi;Izumi Takashi, Journal of radiation research, 50, 2
    DOI
  • Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1., Hirano Tohko;Kishi Mikiko;Sugimoto Hiroyuki;Taguchi Ryo;Obinata Hideru;Ohshima Noriyasu;Tatei Kazuaki;Izumi Takashi, 09 May 2009, Biochimica et biophysica acta, 1791, 8
    DOI
  • Identification and analysis of two splice variants of human G2A generated by alternative splicing., Ogawa Ai;Obinata Hideru;Hattori Tomoyasu;Kishi Mikiko;Tatei Kazuaki;Ishikawa Osamu;Izumi Takashi, 23 Oct. 2009, The Journal of pharmacology and experimental therapeutics, 332, 2
    DOI
  • Detection of G protein-coupled receptor-mediated cellular response involved in cytoskeletal rearrangement using surface plasmon resonance., Chen Kexin;Obinata Hideru;Izumi Takashi, 16 Dec. 2009, Biosensors & bioelectronics, 25, 7
    DOI
  • 【機能性脂質・脂肪酸の多彩な生理活性と病態形成】スフィンゴシン1リン酸シグナルと血管医学, ;, Jul. 2016, 17, 2, 127
  • 可溶性2-アラキドノイルグリセロール産生酵素、DDHD2の酵素学的解析, ;;;;;;, May 2016, 58, 176
  • 群馬大学全体を統合した研究支援体制の強化　群馬大学におけるオミクス解析体制, ;, Aug. 2016, 66, 3, 242
  • リアルタイムPCR法の基礎, 大日方 英, Jul. 2017, 2017, 195
  • 膜貫通型リゾホスホリパーゼD、GDE4過剰発現細胞における脂質の網羅的解析, ;;;;;;, Dec. 2017, 2017年度, [2P
  • スフィンゴシン1リン酸の新規担体分子の探索, ;;;;;;, Dec. 2017, 2017年度, [3P
  • 【脂質クオリティ　生命機能と健康を支える脂質の多様性】(第3章)リポクオリティによる疾患制御　スフィンゴシン1リン酸による生体機能の制御, 大日方 英, Jun. 2018, 36, 10, 1687
  • 【リゾリン脂質メディエーター研究の最前線】S1PシャペロンとしてのApoMの機能, 大日方 英, Oct. 2018, 90, 5, 588
  • [Oxidized free fatty acids as lipid mediators and functions of G2A as their receptor]., Kishimoto Koji;Obinata Hideru;Kishi Mikiko;Ohshima Noriyasu;Tatei Kazuaki;Izumi Takashi, Seikagaku. The Journal of Japanese Biochemical Society, 83, 6
  • Protein purification and cloning of diacylglycerol lipase from rat brain., Aso Chizu;Araki Mari;Ohshima Noriyasu;Tatei Kazuaki;Hirano Tohko;Obinata Hideru;Kishi Mikiko;Kishimoto Koji;Konishi Akimitsu;Goto Fumio;Sugimoto Hiroyuki;Izumi Takashi, 19 Jan. 2016, Journal of biochemistry, 159, 6
    DOI
  • Enzymatic characterization of recombinant rat DDHD2: a soluble diacylglycerol lipase., Araki Mari;Ohshima Noriyasu;Aso Chizu;Konishi Akimitsu;Obinata Hideru;Tatei Kazuaki;Izumi Takashi, 19 May 2016, Journal of biochemistry, 160, 5
    DOI
  • An engineered S1P chaperone attenuates hypertension and ischemic injury., Swendeman Steven L;Xiong Yuquan;Cantalupo Anna;Yuan Hui;Burg Nathalie;Hisano Yu;Cartier Andreane;Liu Catherine H;Engelbrecht Eric;Blaho Victoria;Zhang Yi;Yanagida Keisuke;Galvani Sylvain;Obinata Hideru;Salmon Jane E;Sanchez Teresa;Di Lorenzo Annarita;Hla Timothy, 15 Aug. 2017, Science signaling, 10, 492
    DOI
  • Metabolic activity by 18F-FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC., Kaira Kyoichi;Higuchi Tetsuya;Naruse Ichiro;Arisaka Yukiko;Tokue Azusa;Altan Bolag;Suda Satoshi;Mogi Akira;Shimizu Kimihiro;Sunaga Noriaki;Hisada Takeshi;Kitano Shigehisa;Obinata Hideru;Yokobori Takehiko;Mori Keita;Nishiyama Masahiko;Tsushima Yoshihito;Asao Takayuki, 21 Aug. 2017, European journal of nuclear medicine and molecular imaging, 45, 1
    DOI
  • Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice., Umbarawan Yogi;Syamsunarno Mas Rizky A A;Obinata Hideru;Yamaguchi Aiko;Sunaga Hiroaki;Matsui Hiroki;Hishiki Takako;Matsuura Tomomi;Koitabashi Norimichi;Obokata Masaru;Hanaoka Hirofumi;Haque Anwarul;Kunimoto Fumio;Tsushima Yoshito;Suematsu Makoto;Kurabayashi Masahiko;Iso Tatsuya, 20 Sep. 2017, Metabolism: clinical and experimental, 77
    DOI
  • Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice., Umbarawan Yogi;Syamsunarno Mas Rizky A A;Koitabashi Norimichi;Yamaguchi Aiko;Hanaoka Hirofumi;Hishiki Takako;Nagahata-Naito Yoshiko;Obinata Hideru;Sano Motoaki;Sunaga Hiroaki;Matsui Hiroki;Tsushima Yoshito;Suematsu Makoto;Kurabayashi Masahiko;Iso Tatsuya, Cardiovascular research, 114, 8
    DOI
  • Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure., Umbarawan Yogi;Syamsunarno Mas Rizky A A;Koitabashi Norimichi;Obinata Hideru;Yamaguchi Aiko;Hanaoka Hirofumi;Hishiki Takako;Hayakawa Noriyo;Sano Motoaki;Sunaga Hiroaki;Matsui Hiroki;Tsushima Yoshito;Suematsu Makoto;Kurabayashi Masahiko;Iso Tatsuya, 13 Aug. 2018, Scientific reports, 8, 1
    DOI
  • Sphingosine 1-phosphate and inflammation., Obinata Hideru;Hla Timothy, International immunology, 31, 9
    DOI
  • Light Stress-Induced Increase of Sphingosine 1-Phosphate in Photoreceptors and Its Relevance to Retinal Degeneration., Terao Ryo;Honjo Megumi;Ueta Takashi;Obinata Hideru;Izumi Takashi;Kurano Makoto;Yatomi Yutaka;Koso Hideto;Watanabe Sumiko;Aihara Makoto, 26 Jul. 2019, International journal of molecular sciences, 20, 15
    DOI
  • Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice., Obinata Hideru;Kuo Andrew;Wada Yukata;Swendeman Steven;Liu Catherine H;Blaho Victoria A;Nagumo Rieko;Satoh Kenichi;Izumi Takashi;Hla Timothy, 28 Aug. 2019, Journal of lipid research, 60, 11
    DOI
  • Activation of the Sphingosine 1 Phosphate-Rho Pathway in Pterygium and in Ultraviolet-Irradiated Normal Conjunctiva., Igarashi Nozomi;Honjo Megumi;Fujishiro Takashi;Toyono Tetsuya;Ono Takashi;Mori Yosai;Miyata Kazunori;Obinata Hideru;Aihara Makoto, 20 Sep. 2019, International journal of molecular sciences, 20, 19
    DOI
  • Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level., Tanaka Yuji;Konishi Akimitsu;Obinata Hideru;Tsuneoka Makoto, 10 Dec. 2019, Scientific reports, 9, 1
    DOI
  • CD36 Expression Is Associated with Cancer Aggressiveness and Energy Source in Esophageal Squamous Cell Carcinoma., Yoshida Tomonori;Yokobori Takehiko;Saito Hideyuki;Kuriyama Kengo;Kumakura Yuji;Honjo Hiroaki;Hara Keigo;Sakai Makoto;Miyazaki Tatsuya;Obinata Hideru;Erkhem-Ochir Bilguun;Gombodorj Navchaa;Sohda Makoto;Saeki Hiroshi;Kuwano Hiroyuki;Shirabe Ken, 11 Jun. 2020, Annals of surgical oncology
    DOI
  • Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription., Tanaka Yuji;Obinata Hideru;Konishi Akimitsu;Yamagiwa Noriyuki;Tsuneoka Makoto, 10 Oct. 2020, Cells, 9, 10
    DOI
  • リゾリン脂質メディエーター: 産生・輸送と新たな生理機能　シャペロンシステムによるS1P機能の制御, 大日方 英, Sep. 2019, 92回, [2S11a
  • Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats, Jiang, Weiru;Kakizaki, Toshikazu;Fujihara, Kazuyuki;Miyata, Shigeo;Zhang, Yue;Suto, Takashi;Kato, Daiki;Saito, Shigeru;Shibasaki, Koji;Ishizaki, Yasuki;Isoda, Koji;Yokoo, Hideaki;Obinata, Hideru;Hirano, Touko;Miyasaka, Yoshiki;Mashimo, Tomoji;Yanagawa, Yuchio, 2022, FASEB JOURNAL, 36, 2
    DOI
  • Cu-64-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity, Nachankar, Ankita;Oike, Takahiro;Hanaoka, Hirofumi;Kanai, Ayaka;Sato, Hiro;Yoshida, Yukari;Obinata, Hideru;Sakai, Makoto;Osu, Naoto;Hirota, Yuka;Takahashi, Akihisa;Shibata, Atsushi;Ohno, Tatsuya, 2021, CANCERS, 13, 24
    DOI
  • Reduced Fatty Acid Use from CD36 Deficiency Deteriorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice, Umbarawan, Yogi;Kawakami, Ryo;Syamsunarno, Mas Rizky A. A.;Obinata, Hideru;Yamaguchi, Aiko;Hanaoka, Hirofumi;Hishiki, Takako;Hayakawa, Noriyo;Koitabashi, Norimichi;Sunaga, Hiroaki;Matsui, Hiroki;Kurabayashi, Masahiko;Iso, Tatsuya, 2021, METABOLITES, 11, 12
    DOI
  • Disordered branched chain amino acid catabolism in pancreatic islets is associated with postprandial hypersecretion of glucagon in diabetic mice, Wada, Eri;Kobayashi, Masaki;Kohno, Daisuke;Kikuchi, Osamu;Suga, Takayoshi;Matsui, Sho;Yokota-Hashimoto, Hiromi;Honzawa, Norikiyo;Ikeuchi, Yuichi;Tsuneoka, Haruka;Hirano, Touko;Obinata, Hideru;Sasaki, Tsutomu;Kitamura, Tadahiro, 2021, JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 97
    DOI
  • CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function, Mao, De Yu;Kleinjan, Matthew L.;Jilishitz, Irina;Swaminathan, Bhairavi;Obinata, Hideru;Komarova, Yulia A.;Bayless, Kayla J.;Hla, Timothy;Kitajewski, Jan K., 2021, SCIENCE SIGNALING, 14, 679
    DOI
  • LTBP2 is a Novel Marker in Hepatocellular Carcinoma, Erkhem-Ochir, Bilguun;Chivarina, Barbara;Yokobori, Takehiko;Turtoi, Evgenia;Obinata, Hideru;Navchaa, Gombodorj;Minamishima, Yoji Andrew;Matsuzaki, Toshiyuki;Saeki, Hiroshi;Nishiyama, Masahiko;Shirabe, Ken;Turtoi, Andrei, 2021, CANCER SCIENCE, 112, 755, 755
  • Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice, Miyata, Shigeo;Kakizaki, Toshikazu;Fujihara, Kazuyuki;Obinata, Hideru;Hirano, Touko;Nakai, Junichi;Tanaka, Mika;Itohara, Shigeyoshi;Watanabe, Masahiko;Tanaka, Kenji F.;Abe, Manabu;Sakimura, Kenji;Yanagawa, Yuchio, 2021, MOLECULAR BRAIN, 14, 1
    DOI
  • Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy, Umbarawan, Yogi;Kawakami, Ryo;Syamsunarno, Mas Rizky A. A.;Koitabashi, Norimichi;Obinata, Hideru;Yamaguchi, Aiko;Hanaoka, Hirofumi;Hishiki, Takako;Hayakawa, Noriyo;Sunaga, Hiroaki;Matsui, Hiroki;Kurabayashi, Masahiko;Iso, Tatsuya, 2020, SCIENTIFIC REPORTS, 10, 1
    DOI
  • Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription, Tanaka, Yuji;Obinata, Hideru;Konishi, Akimitsu;Yamagiwa, Noriyuki;Tsuneoka, Makoto, 2020, CELLS, 9, 10
    DOI
  • CD36 Expression Is Associated with Cancer Aggressiveness and Energy Source in Esophageal Squamous Cell Carcinoma, Yoshida, Tomonori;Yokobori, Takehiko;Saito, Hideyuki;Kuriyama, Kengo;Kumakura, Yuji;Honjo, Hiroaki;Hara, Keigo;Sakai, Makoto;Miyazaki, Tatsuya;Obinata, Hideru;Erkhem-Ochir, Bilguun;Gombodorj, Navchaa;Sohda, Makoto;Saeki, Hiroshi;Kuwano, Hiroyuki;Shirabe, Ken, 2021, ANNALS OF SURGICAL ONCOLOGY, 28, 2, 1217, 1227
    DOI
  • Identification and Analysis of Two Splice Variants of Human G2A Generated by Alternative Splicing, Ogawa, Ai;Obinata, Hideru;Hattori, Tomoyasu;Kishi, Mikiko;Tatei, Kazuaki;Ishikawa, Osamu;Izumi, Takashi, 2010, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 332, 2, 469, 478
    DOI
  • G2A as a receptor for oxidized free fatty acids, Obinata, Hideru;Izumi, Takashi, 2009, PROSTAGLANDINS & OTHER LIPID MEDIATORS, 89, 3-4, 66, 72
    DOI
  • Utility of glycosylation regulation for pancreatic cancer treatment, Kawabata, Reika;Obinata, Hideru;Gombodorj, Navchaa;Yokobori, Takehiko, 2022, CANCER SCIENCE, 113, 1764, 1764
  • 2,2,6,6-Tetramethylpiperidine-1-oxyl acts as a volatile inhibitor of ferroptosis and neurological injury, Mizuno, Hiroyuki;Kubota, Chisato;Takigawa, Yuta;Shintoku, Ryosuke;Kannari, Naokatsu;Muraoka, Takako;Obinata, Hideru;Yoshimoto, Yuhei;Kanazawa, Masato;Koshiishi, Ichiro;Torii, Seiji, 2022, JOURNAL OF BIOCHEMISTRY, 172, 2, 71, 78
    DOI
  • リゾリン脂質メディエーター: 産生・輸送と新たな生理機能　シャペロンシステムによるS1P機能の制御, 大日方 英, Sep. 2019, 92回, [2S11a
  • 血中スフィンゴシン1リン酸の産生および分解過程におけるキャリアタンパク質の役割, ;;;, Sep. 2020, 93回, [1Z02
  • 膵α細胞における分岐鎖アミノ酸代謝異常は糖尿病のグルカゴン過剰分泌に関与する, ;;;;;;, Apr. 2021, 97, 1, 319
  • 腎臓における脂肪酸処理の正しく評価されていないメカニズム　脂肪酸再吸収のための優れた機能(Unappreciated mechanisms of fatty acids handling in the kidney: Remarkable capability for fatty acid reabsorption), ;;;;;;;;;, Apr. 2021, 96, 4, 1116
  • 膵α細胞における分岐鎖アミノ酸代謝異常は糖尿病のグルカゴン過剰分泌に関与する, ;;;;;;, May 2021, 64, Suppl.1, YIA
  • 腎尿細管上皮細胞における二重の脂肪酸取り込み機構の同定, ;;;;;;;;;;;, Jun. 2021, 44, 1, 43
  • 膵がん治療における糖修飾制御の有用性, ;;;, Sep. 2021, 80回, [P16
  • 低分子化合物によるフェロトーシス感受性の調節, ;;;;;;, Nov. 2021, 94回, [P
  • Reduced fatty acid uptake aggravates cardiac contractile dysfunction in streptozotocin-induced diabetic cardiomyopathy., Umbarawan Yogi;Kawakami Ryo;Syamsunarno Mas Rizky A A;Koitabashi Norimichi;Obinata Hideru;Yamaguchi Aiko;Hanaoka Hirofumi;Hishiki Takako;Hayakawa Noriyo;Sunaga Hiroaki;Matsui Hiroki;Kurabayashi Masahiko;Iso Tatsuya, 30 Nov. 2020, Scientific reports, 10, 1
    DOI
  • Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice., Miyata Shigeo;Kakizaki Toshikazu;Fujihara Kazuyuki;Obinata Hideru;Hirano Touko;Nakai Junichi;Tanaka Mika;Itohara Shigeyoshi;Watanabe Masahiko;Tanaka Kenji F;Abe Manabu;Sakimura Kenji;Yanagawa Yuchio, 07 Jan. 2021, Molecular brain, 14, 1
    DOI
  • CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function., Mao De Yu;Kleinjan Matthew L;Jilishitz Irina;Swaminathan Bhairavi;Obinata Hideru;Komarova Yulia A;Bayless Kayla J;Hla Timothy;Kitajewski Jan K, 20 Apr. 2021, Science signaling, 14, 679
    DOI
  • Disordered branched chain amino acid catabolism in pancreatic islets is associated with postprandial hypersecretion of glucagon in diabetic mice., Wada Eri;Kobayashi Masaki;Kohno Daisuke;Kikuchi Osamu;Suga Takayoshi;Matsui Sho;Yokota-Hashimoto Hiromi;Honzawa Norikiyo;Ikeuchi Yuichi;Tsuneoka Haruka;Hirano Touko;Obinata Hideru;Sasaki Tsutomu;Kitamura Tadahiro, 28 Jun. 2021, The Journal of nutritional biochemistry, 97
    DOI
  • Reduced Fatty Acid Use from CD36 Deficiency Deteriorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice., Umbarawan Yogi;Kawakami Ryo;Syamsunarno Mas Rizky A A;Obinata Hideru;Yamaguchi Aiko;Hanaoka Hirofumi;Hishiki Takako;Hayakawa Noriyo;Koitabashi Norimichi;Sunaga Hiroaki;Matsui Hiroki;Kurabayashi Masahiko;Iso Tatsuya, 17 Dec. 2021, Metabolites, 11, 12
    DOI
  • Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats., Jiang Weiru;Kakizaki Toshikazu;Fujihara Kazuyuki;Miyata Shigeo;Zhang Yue;Suto Takashi;Kato Daiki;Saito Shigeru;Shibasaki Koji;Ishizaki Yasuki;Isoda Koji;Yokoo Hideaki;Obinata Hideru;Hirano Touko;Miyasaka Yoshiki;Mashimo Tomoji;Yanagawa Yuchio, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36, 2
    DOI
  • 2,2,6,6-Tetramethylpiperidine-1-oxyl acts as a volatile inhibitor of ferroptosis and neurological injury., Mizuno Hiroyuki;Kubota Chisato;Takigawa Yuta;Shintoku Ryosuke;Kannari Naokatsu;Muraoka Takako;Obinata Hideru;Yoshimoto Yuhei;Kanazawa Masato;Koshiishi Ichiro;Torii Seiji, 03 May 2022, Journal of biochemistry
    DOI
  • 低分子化合物によるフェロトーシス感受性の調節, ;;;;;;, Nov. 2021, 94回, [P
  • 腎臓の脂肪酸取り込み機構全容の解明, ;;;;;;;;;;, Mar. 2022, 97, 5, 1477
  • Activation of the Sphingosine 1 Phosphate-Rho Pathway in Pterygium and in Ultraviolet-Irradiated Normal Conjunctiva, Igarashi, Nozomi;Honjo, Megumi;Fujishiro, Takashi;Toyono, Tetsuya;Ono, Takashi;Mori, Yosai;Miyata, Kazunori;Obinata, Hideru;Aihara, Makoto, 2019, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20, 19
    DOI
  • Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity, Suzuki, Tomohiro;Komatsu, Tetsuro;Shibata, Hiroshi;Tanioka, Akiko;Vargas, Diana;Kawabata-Iwakawa, Reika;Miura, Fumihito;Masuda, Shinnosuke;Hayashi, Mayuko;Tanimura-Inagaki, Kyoko;Morita, Sumiyo;Kohmaru, Junki;Adachi, Koji;Tobo, Masayuki;Obinata, Hideru;Hirayama, Tasuku;Kimura, Hiroshi;Sakai, Juro;Nagasawa, Hideko;Itabashi, Hideyuki;Hatada, Izuho;Ito, Takashi;Inagaki, Takeshi, 2023, NUCLEIC ACIDS RESEARCH, 51, 12, 6120, 6142
    DOI
  • Apolipoprotein M supports S1P production and conservation and mediates prolonged Akt activation via S1PR1 and S1PR3, Kiyozuka, Keisuke;Zhao, Xian;Konishi, Akimitsu;Minamishima, Yoji Andrew;Obinata, Hideru, 2023, JOURNAL OF BIOCHEMISTRY
    DOI
  • Pilot study of plasma creatine riboside as a potential biomarker for cervical cancer, Oike, Takahiro;Osu, Naoto;Yoshimoto, Yuya;Obinata, Hideru;Yoshikawa, Kazuhiro;Harris, Curtis C.;Ohno, Tatsuya, 2023, HELIYON, 9, 6
    DOI
  • O-GlcNAcase is essential for proliferation in KRAS wild-type pancreatic cancer cell, Kawabata, Reika;Zhao, Xian;Gombodorj, Navchaa;Yokobori, Takehiko;Obinata, Hideru, 2023, CANCER SCIENCE, 114, 1886, 1886
  • 膵臓がん細胞におけるO-GlcNAcaseの重要性(Essentiality of O-GlcNAcase in pancreatic cancer cell), ;;;;, Sep. 2023, 82回, 2110
  • 【代謝から紐解く老化・加齢性疾患】分岐鎖アミノ酸代謝の変調と老化・加齢性疾患, ;, Feb. 2024, 48, 1, 3
  • 64Cu-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity., Nachankar Ankita;Oike Takahiro;Hanaoka Hirofumi;Kanai Ayaka;Sato Hiro;Yoshida Yukari;Obinata Hideru;Sakai Makoto;Osu Naoto;Hirota Yuka;Takahashi Akihisa;Shibata Atsushi;Ohno Tatsuya, Dec. 2021, Cancers, 13, 24
    DOI
  • Apolipoprotein M supports S1P production and conservation and mediates prolonged Akt activation via S1PR1 and S1PR3., Kiyozuka Keisuke;Zhao Xian;Konishi Akimitsu;Minamishima Yoji Andrew;Obinata Hideru, Journal of biochemistry, 174, 3
    DOI
  • Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity., Suzuki Tomohiro;Komatsu Tetsuro;Shibata Hiroshi;Tanioka Akiko;Vargas Diana;Kawabata-Iwakawa Reika;Miura Fumihito;Masuda Shinnosuke;Hayashi Mayuko;Tanimura-Inagaki Kyoko;Morita Sumiyo;Kohmaru Junki;Adachi Koji;Tobo Masayuki;Obinata Hideru;Hirayama Tasuku;Kimura Hiroshi;Sakai Juro;Nagasawa Hideko;Itabashi Hideyuki;Hatada Izuho;Ito Takashi;Inagaki Takeshi, Nucleic acids research, 51, 12
    DOI
  • Actin-binding protein filamin B regulates the cell-surface retention of endothelial sphingosine 1-phosphate receptor 1., Zhao Xian;Kiyozuka Keisuke;Konishi Akimitsu;Kawabata-Iwakawa Reika;Minamishima Yoji Andrew;Obinata Hideru, May 2023, The Journal of biological chemistry, 299, 7
    DOI
  • Pilot study of plasma creatine riboside as a potential biomarker for cervical cancer., Oike Takahiro;Osu Naoto;Yoshimoto Yuya;Obinata Hideru;Yoshikawa Kazuhiro;Harris Curtis C;Ohno Tatsuya, May 2023, Heliyon, 9, 6
    DOI
  • Aquaporin-5 Protein Is Selectively Reduced in Rat Parotid Glands under Conditions of Fasting or a Liquid Diet., Fujita Yoshie;Taniguchi Akie;Yamamoto Hanako;Obinata Hideru;Kogo Hiroshi;Iizuka-Kogo Akiko;Ikezawa Maiko;Tajika Yukiko;Yokoo Satoshi;Matsuzaki Toshiyuki, Feb. 2024, Acta histochemica et cytochemica, 57, 1
    DOI
  • バイオインフォマティクス・生体変容　代謝物解析から迫る細胞・個体老化　分岐鎖アミノ酸代謝の変調を中心に, 大日方 英, Jun. 2023, 47, 2, 46
  • テロメア短縮系を用いた効率的な複製老化系の樹立および分岐鎖アミノ酸代謝の細胞老化における役割の解析, ;;;;;;, Oct. 2023, 96回, [1P
  • 膵臓がん細胞におけるO-GlcNAcaseの重要性(Essentiality of O-GlcNAcase in pancreatic cancer cell), ;;;;, Sep. 2023, 82回, 2110
  • 【代謝から紐解く老化・加齢性疾患】分岐鎖アミノ酸代謝の変調と老化・加齢性疾患, ;, Feb. 2024, 48, 1, 3
  • Segatella copri JCM 13464Tの大麦β-グルカン代謝遺伝子群の同定, ;;;;;;;, Jun. 2024, 35, 2, 156
  • 子宮頸癌における血漿Creatine Riboside検出の概念実証研究, ;;;;, Jul. 2024, 66回, 261
  • 腎臓の脂肪酸取り込み機構全容の解明, ;;;;;;;;;;, Mar. 2022, 97, 5, 1477
  • KRAS野生型膵がんにおけるO-GlcNAc分解酵素の重要性(O-GleNAcase is essential for proliferation in KRAS wild-type pancreatic cancer cell.), ;;;;, Sep. 2022, 81回, P
  • バイオインフォマティクス・生体変容　代謝物解析から迫る細胞・個体老化　分岐鎖アミノ酸代謝の変調を中心に, 大日方 英, Jun. 2023, 47, 2, 46
  • アクチン結合蛋白フィラミンBは受容体を細胞表面に維持することで内皮スフィンゴシン1リン酸受容体1の機能を制御している(Actin-binding protein Filamin B regulates endothelial sphingosine 1-phosphate receptor 1 functions by keeping the receptor on cell-surface), ;;;;, Oct. 2023, 96回, [1P
  • テロメア短縮系を用いた効率的な複製老化系の樹立および分岐鎖アミノ酸代謝の細胞老化における役割の解析, ;;;;;;, Oct. 2023, 96回, [1P
  • アクチン結合蛋白フィラミンBは受容体を細胞表面に維持することで内皮スフィンゴシン1リン酸受容体1の機能を制御している(Actin-binding protein Filamin B regulates endothelial sphingosine 1-phosphate receptor 1 functions by keeping the receptor on cell-surface), ;;;;, Oct. 2023, 96回, [1P
  • 血中スフィンゴシン1リン酸の産生および分解過程におけるキャリアタンパク質の役割, ;;;, Sep. 2020, 93回, [1Z02

MISC

  • S1PシャペロンとしてのApoMの機能, 大日方 英, Oct. 2018, 90, 5, 588, 595, Introduction scientific journal
  • スフィンゴシン1リン酸シグナルと血管医学, 大日方 英,Hla Timothy, 2016, 17, 2, 127, 136, Introduction scientific journal
  • Oxidized free fatty acids as lipid mediators and functions of G2A as their receptor., Kishimoto K,Obinata H,Kishi M,Ohshima N,Tatei K,Izumi T, Jun. 2011, Seikagaku. The Journal of Japanese Biochemical Society, 83, 6, 545, 554, Introduction scientific journal
  • プロトン感知性GPCR研究の展開, 大日方英,和泉孝志, 2008, 80, 2
  • 表皮角化細胞におけるGタンパク質共役型受容体G2Aの生理作用, 大日方英,服部友保,小川愛,平野瞳子,陳可欣,Melisa Intan Barliana,岸美紀子,立井一明,和泉孝志, 2007, 49, 38, 40
  • オーファン受容体のリガンド探索 -新たな生命現象の理解と創薬を目指して-, 大日方英,和泉孝志, 2007, 26, 3, 247, 253
  • Gタンパク質共役型受容体G2Aのリガンド同定とシグナル解析, 大日方 英,服部 友保,立井 一明,和泉 孝志, 2006, 48, 301, 303
  • Bioluminescence Resonance energy transfer によるロイコトリエンB4受容体二量体化の検出, 岸 美紀子,大日方 英,和泉 孝志, 2005, 47, 205, 208
  • Effects of heavy-ion irradiation on the early embryo of Drosophila melanogaster, TATEI KAZUAKI,IZUMI TAKASHI,OBINATA HIDERU,NONAKA TETUO,NAKANO TAKASHI, 2004, TIARA Annual Report 2004, 166-168
  • Effects of heavy-ion irradiation on the early embryo of Drosophila melanogaster, TATEI KAZUAKI,IZUMI TAKASHI,OBINATA HIDERU,NONAKA TETUO,NAKANO TAKASHI, 2004, 166-168
  • 5-oxo-ETE受容体の活性化が引き起こすケモタキシスと細胞内セカンドメッセンジャー濃度変化の測定, 小池太悟,大日方 英,和泉 孝志,武田 茂樹, 2003, 45, 189, 192
  • ロイコトリエンB4受容体のグルココルチコイドによる発現制御, 大日方 英,和泉 孝志,横溝岳彦,清水孝雄, 2001, 43, 107, 109
  • 受容体の基礎知識と新たな展開, 大日方 英,和泉 孝志, 2001, 25, 3, 456, 467

Books etc

  • 実験医学増刊 脂質クオリティ, Contributor, Jun. 2018
  • 遺伝子医学MOOK 最新生理活性脂質研究 -実験手法、基礎的知識とその応用- （監修 横溝岳彦）, Contributor, 2013
  • 実験医学増刊 分子から個体へと深化する脂質生物学 （編集 佐々木雄彦、横溝岳彦、竹縄忠臣）, Contributor, Oct. 2010
  • 麻酔管理に関連する受容体（編集 大下修造）, Contributor, Apr. 2003, ISBN: 4880037036
  • ポストシークエンスタンパク質実験法４ 構造・機能解析の実際（大島泰郎・鈴木紘一・藤井義明・村松喬 編）, Contributor, 2003, ISBN: 4807911376

Presentations

  • リアルタイムPCR法の基礎, 大日方 英, 第42回組織細胞化学講習会, Aug. 2017, Japanese, Domestic conference
  • Regulation of S1P functions by a chaperone system, OBINATA Hideru, The 92nd Annual Meeting of the Japanese Biochemical Society, Sep. 2019, Japanese, Domestic conference
  • 家庭環境内における重金属類暴露シナリオの解明ー調査方法の確立, 仲井邦彦,龍田希,岩井美幸,磯部友彦,西浜柚季子,中山祥嗣,和泉孝志,大日方英,大嶋紀安,ロマナスハレツキス, 第89回日本衛生学会学術総会, Feb. 2019
  • 化学物質曝露評価における定量的メタボロミクスの現状と課題, 和泉孝志,大日方英,大嶋紀安,Romanas Chaleckis, 第65回質量分析総合討論会, 2017
  • Novel S1P chaperone activity in the plasma from ApoM/albumin-double knockout mice, Obinata H,Wada Y,Kuo A,Swendeman S,Liu C,Izumi T,Hla T, 2018分子生物学会年会, Nov. 2018
  • メトホルミンはKDM2A依存的なrRNA転写抑制及び細胞増殖抑制を引き起こす, 田中祐司,小西昭充,大日方英,南雲美奈代,和泉桃佳,岡本健吾,常岡誠, 2018分子生物学会年会, Nov. 2018
  • メトホルミンは細胞内コハク酸量を減少させ、KDM2A依存的なrRNA転写抑制を誘導する, 田中祐司,大日方英,小西昭充,南雲美奈代,和泉桃佳,岡本健吾,常岡誠, 第５回リボソームミーティング, Sep. 2018
  • スフィンゴシン１リン酸の新規担体分子の探索, 和田優,大日方英,Swendeman S,Catherine L,南雲理恵子,Hla T,和泉孝志, 生命科学系学会合同年次大会 ConBio2017, Dec. 2017, Japanese, Domestic conference
  • 膜貫通型リゾホスホリパーゼD、GDE4過剰発現細胞における脂質の網羅的解析, 大嶋紀安,荒木麻理,大日方英,小西昭充,鈴木啓,立井一明,和泉孝志, 生命科学系学会合同年次大会 ConBio2017, Dec. 2017, Japanese, Domestic conference
  • Multi-Omits Approaches to Integrative Analysis of Diseases -from bench to clinic-, OBINATA Hideru, The 3rd International Symposium of Gunma University Initiative for Advance Research, Oct. 2016, English, International conference
  • 群馬大学におけるオミクス解析体制, 大日方 英, 第63回北関東医学会総会, Sep. 2016, Japanese, Domestic conference
  • Analysis of Anti-Atherogenic Properties of HDL-Bound S1P for Vascular Health, OBINATA Hideru, The 3rd International Symposium of Gunma University Program for Local Area Open Innovation R&D Human Resources, Feb. 2016, English, International conference
  • 発芽的血管新生の制御と血流ズリ応力の受容におけるS1P1受容体の役割, Obinata H,Jung B,Galvani S,Hla T, 日本脂質生化学会, 2013, Japanese, Domestic conference
  • Sphigonsine 1-phosphate receptor 1 mediates the endothelial cell responses to fluid shear stress, Obinata H,Galvani S,Jung B,Hla T, 日本生化学会, 2012, English, Domestic conference
  • Sphigosine 1 phosphate receptor signaling in endothelial responses to fluid shear stress, Obinata H,Jung B,Galvani S,Hla T, Gordon Research Conference - Vascular Cell Biology -, Jan. 2013, English, International conference
  • Apolipoprotein M serves as a specific carrier for endothelium-protective sphingosine 1-phosphate associated with HDL, Obinata H,Christoffersen C,Kumaraswamy S,Galvani S,Ahnstrom J,Sevvana M,Egerer-Siever C,Muller Y,Nielsen LB,Dahlback B,Hla T, North American Vascular Biology Organization annual meeting 2011, 2011, English, International conference
  • Novel function of 9 (S)-hydroxyoctadecadienoic acid on proliferation of T cells., Japanese conference on the biochemistry of lipids, 2010
  • Analysis of the dimerization/ oligomerization of Leukotriene B4 receptors by BRET, Keystone Symposia, 2006
  • ロイコトリエンB4受容体の二量体化・多量体化メカニズムの解析 Analysis of the mechanism of dimerization/ oligomerization of leukotriene B4 Receptors, 第２８回日本分子生物学会年会, 2005
  • Bioluminescence Resonance Energy TransferによるロイコトリエンB4受容体二量体の検出 Detection of the dimerization of the leukotriene B4 receotor using BRET, 第47回脂質生化学会, 2005
  • Bioluminescence Resonance Energy Transfer（BRET)を用いたロイコトリエンB4受容体二量体化の解析, 分子研研究会『ロドプシンの仲間・Gタンパク質共役型レセプターの機能と構造』, 2005
  • Detection of GPCR activity by surface plasmon resonance (SPR) in living cells, 20th IUBMB International Congress of Biochemistry and Molecular Biology, 2006
  • Partial purification of natural ligands for orphan G-protein coupled receptors, 20th IUBMB International Congress of Biochemistry and Molecular Biology, 2006
  • A biological role of G2A in human keratinocytes as a receptor for oxidized free fatty acids, Keystone Symposia (Eicosanoids in Inflammation and Chronic Diseases), 2006
  • Effects of heavy-ion irradiation on the early embryo of Drosophila melanogaster, 21st century COE Program, The second international symposium on biomedical research using accelerator technology., 2005
  • Human G2A is a G protein-coupled receptor activated by 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids, 20th IUBMB International Congress of Biochemistry and Molecular Biology, 2006
  • G タンパク質共役型受容体 G2A のリガンド同定とシグナル解析, 第48回脂質生化学会, 2006
  • Identification of human G2A as a receptor for oxidized free fatty acids, 第78回日本生化学会大会, 2005
  • ロイコトリエンB4受容体-1のグルココルチコイドによる発現上昇, 第75回日本生化学会大会, 2002
  • Gタンパク質共役型受容体G2Aのリガンド同定と皮膚における生理機能の解析, 群馬大学21世紀COE若手研究者シンポジウム「生体情報伝達研究のフロンティア」, 2006
  • Detection of GPCR activity by surface plasmon resonance (SPR) in living cells, Keystone Symposia (G Protein-Coupled Receptors Evolving Concepts and New Techniques), 2006
  • Gタンパク質共役型受容体G2Aのスプライシングバリアントの同定と機能解析, 第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会, 2007
  • 生細胞におけるGPCR活性の表面プラズモン共鳴(SPR)による観察, 第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会, 2007
  • ロイコトリエンB4受容体-1のグルココルチコイドによる発現および機能の亢進, 第5回東京プロスタノイド研究会, 2002
  • ロイコトリエンB4受容体発現に及ぼすグルココルチコイドの影響, 第23回日本分子生物学会年会, 2000
  • 表皮角化細胞におけるGタンパク質共役型受容体G2Aの生理作用, 第49回脂質生化学会, 2007
  • Oxidized free fatty acid-G2A signaling mediates alarm signal under oxidative stress, 3rd International conference on phospholipase A2 and lipid mediators, 2007
  • G2A mediates signals of oxidized free fatty acids in human keratinocytes, 3rd International conference on phospholipase A2 and lipid mediators, 2007
  • Identification of Ets-1 as an Important Transcriptional Activator of CTP:Phosphocholine Cytidylyltransferase a in COS-7 Cells and Co-Activation with Transcriptional Enhancer Factor-4, 第76回日本生化学会大会, 2003
  • Analysis of the dimerization / oligomerization of Leukotriene B4 receptors by BRET, Keystone Symposia (G Frotein-Coupled Receptors Evolving Concepts and New Techniques), 2006
  • 9-HODE induces cell growth arrest in Jurkat T lymphocytes., 第82回日本生化学会, 2009
  • Ceramide induces myogenic differentiation and apoptosis in Drosophila Schneider cells, 4th International Conference on Phospholipase A2 and Lipid Mediators, 2009
  • 9-hydroxyoctadecadienoic acid, one of the oxidized metabolites of linoleic acid, induces cell cycle arrest in the G1 phase in primary human keratinosytes, 第31回日本分子生物学会年会 第81回日本生化学会大会 合同大会, 2008
  • Ceramide induces myogenic differentiation and apoptosis in Drosophila Schneider cells, The 21st Century COE Program, The Fourth International Symposium on Biomedical Research Using Accelerator Technology, 2008
  • ショウジョウバエ培養細胞Schneider株においてセラミドは筋分化とアポトーシスを誘導する, 日本脂質生化学会, 2009
  • 表面プラズモン共鳴現象を用いた生細胞におけるGPCRシグナルの検出., 日本脂質生化学会, 2009
  • 表面プラズモン共鳴現象による生細胞におけるRTKシグナルの検出, 日本生化学会, 2009
  • ショウジョウバエ培養細胞Schneider株においてセラミドは筋分化とアポトーシスを誘導する, 日本分子生物学会年会, 2009
  • 酸化遊離脂肪酸をリガンドとするG2Aの機能とサブタイプの解析, 日本脂質生化学会, 2010
  • アシルプロテインチオエステラーゼ1/リゾホスホリパーゼ1の活性と細胞内局在, 日本脂質生化学会, 2010
  • Oxidized free fatty acids mediate alarm signals through a G-protein coupled receptor, G2A, 4th International Conference on Phospholipase A2 and Lipid Mediators, 2009
  • 9-hydroxyoctadecadienoic acid, one of the oxidized metabolites of linoleic acid, induces cell cycle arrest in the G1 phase in primary human keratinocytes, International Workshop on Cell Regulation in Division and Arrest Under Stress, 2008
  • Analysis of the dimerization/ oligomerization of Leukotriene B4 receptors by BRET, Keystone Symposia, 2006
  • Detection of GPCR activity by surface plasmon resonance (SPR) in living cells, 20th IUBMB International Congress of Biochemistry and Molecular Biology, 2006
  • Partial purification of natural ligands for orphan G-protein coupled receptors, 20th IUBMB International Congress of Biochemistry and Molecular Biology, 2006
  • A biological role of G2A in human keratinocytes as a receptor for oxidized free fatty acids, Keystone Symposia (Eicosanoids in Inflammation and Chronic Diseases), 2006
  • Effects of heavy-ion irradiation on the early embryo of Drosophila melanogaster, 21st century COE Program, The second international symposium on biomedical research using accelerator technology., 2005
  • Human G2A is a G protein-coupled receptor activated by 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids, 20th IUBMB International Congress of Biochemistry and Molecular Biology, 2006
  • Identification of human G2A as a receptor for oxidized free fatty acids, 第78回日本生化学会大会, 2005
  • Detection of GPCR activity by surface plasmon resonance (SPR) in living cells, Keystone Symposia (G Protein-Coupled Receptors Evolving Concepts and New Techniques), 2006
  • Oxidized free fatty acid-G2A signaling mediates alarm signal under oxidative stress, 3rd International conference on phospholipase A2 and lipid mediators, 2007
  • G2A mediates signals of oxidized free fatty acids in human keratinocytes, 3rd International conference on phospholipase A2 and lipid mediators, 2007
  • Identification of Ets-1 as an Important Transcriptional Activator of CTP:Phosphocholine Cytidylyltransferase a in COS-7 Cells and Co-Activation with Transcriptional Enhancer Factor-4, 第76回日本生化学会大会, 2003
  • Analysis of the dimerization / oligomerization of Leukotriene B4 receptors by BRET, Keystone Symposia (G Frotein-Coupled Receptors Evolving Concepts and New Techniques), 2006
  • Ceramide induces myogenic differentiation and apoptosis in Drosophila Schneider cells, 4th International Conference on Phospholipase A2 and Lipid Mediators, 2009
  • Ceramide induces myogenic differentiation and apoptosis in Drosophila Schneider cells, The 21st Century COE Program, The Fourth International Symposium on Biomedical Research Using Accelerator Technology, 2008
  • Oxidized free fatty acids mediate alarm signals through a G-protein coupled receptor, G2A, 4th International Conference on Phospholipase A2 and Lipid Mediators, 2009
  • 9-hydroxyoctadecadienoic acid, one of the oxidized metabolites of linoleic acid, induces cell cycle arrest in the G1 phase in primary human keratinocytes, International Workshop on Cell Regulation in Division and Arrest Under Stress, 2008

Industrial Property Rights

  • Patent right, 特願2007-126063, 2007
  • Patent right, 特願PCT/JP2006/312405, 2006
  • Patent right, 特願2005-182051, 2005
  • Patent right, Endothelium protective materials and methods of use, Hla T,Obinata H,Galvani S,Bjorn D,Nielsen LB,Christoffersen C,Blaho V, 特願PCT/WO2012/162392, 2012

Awards

  • NAVBO annual meeting 2011 Poster Award, OBINATA Hideru, North American Vascular Biology Organization, Oct. 2011

Research Projects

  • 2008, 2009, Principal investigator, Competitive research funding
  • 2008, 2009, Principal investigator, Competitive research funding
  • 2008, 2009, Principal investigator, Competitive research funding
  • 2015, 2016, Principal investigator, Competitive research funding
  • 2007, 2008, Principal investigator, Competitive research funding
  • 2007, 2008, Principal investigator, Competitive research funding
  • 2017, 2020, Competitive research funding
  • 1998, 2001, Competitive research funding
  • 2004, 2006, Principal investigator, Competitive research funding
  • 2006, 2007, Competitive research funding
  • 2007, 2008, Principal investigator, Competitive research funding
  • 2017, 2019, Competitive research funding
  • 2016, 2018, Principal investigator, Competitive research funding
  • Ligand？creening？f？rphan？eceptors, Competitive research funding

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