Gunma University, Assistant Professor

2012, Gunma University, Graduate School of Medicine

2001, University of the Ryukyus, Faculty of Medicine, School of Medicine

Gunma University

Life sciences, Anesthesiology

anesthesia

inhibitory neurotransmission

pain

electrophysiology

A case report of pain and its treatment following nerve damage due to occupational electrical injury., Makiko Hardy Yamada, Shigeru Saito, May 2023, The Kitakanto Medical Journal, 73, 2, 159, 162, Scientific journal

Anesthetic management for clipping a giant basilar artery aneurysm with moderate hypothermia, extracorporeal circulation assistance, and propofol infusion. , Yamada M, Nishikawa K, Kawahara F, Yoshikawa D, Saito S, Goto F. , Jul. 2003, Journal of Neurosurgical Anesthesiology

Relationship between arterial oxygen saturation and heart rate variability at high altitudes. , Saito S, Tanobe K, Yamada M, Nishihara F. , Jan. 2005, The American Journal of Emergency Medicine

Carbon dioxide exhalation temporarily increases during electroconvulsive therapy. , Sakurazawa S, Saito S, Yamada M, Nishihara F, Goto F. , 2006, Journal of Anesthesia

Peripheral circulation monitored by surface temperature and autonomic nervous function in hypobaric hypoxic environment: effects of submaximal exercise. , Fukuda-Matsuda E, Yamada M, Tanobe K, Saito S. , Feb. 2007, Intenational Journal of Enviromental Health Researcn

Role of presynaptic mechanisms in propofol-induced facilitation of gamma-amino butyric acid (GABA)-mediated inhibitory neurotransmission., Nishikawa K, Kubo K, Yamada M, Ishizeki J. , Nov. 2007, Masui

A novel bFGF-GH injection therapy for two patients with severe ischemic limb pain. , Ito N, Saito S, Yamada MH, Koizuka S, Obata H, Nishikawa K, Tabata Y. , 2008

Oxygen inhalation using an oxygen concentrator in a low-pressure environment outside of a hospital. , Sakaue H, Suto T, Kimura M, Narahara S, Sato T, Tobe M, Aso C, Kakinuma T, Hardy-Yamada M, Saito S. , Nov. 2008, The American Journal of Emergency Medicine

Altered responses to propofol, but not ketamine, in mice deficient in the 65-kilodalton isoform of glutamate decarboxylase. , Kubo K, Nishikawa K, Hardy-Yamada M, Ishizeki J, Yanagawa Y, Saito S. , Mar. 2009, The Journal of Pharmacology and Experimental Therapeutics

Thermal hyperalgesia via supraspinal mechanisms in mice lacking glutamate decarboxylase 65. , Kubo K, Nishikawa K, Ishizeki J, Hardy-Yamada M, Yanagawa Y, Saito S. , Oct. 2009, The Journal of Pharmacology and Experimental Therapeutics

Impaired glycinergic synaptic transmission and enhanced inflammatory pain in mice with reduced expression of vesicular GABA transporter (VGAT). , Yamada MH, Nishikawa K, Kubo K, Yanagawa Y, Saito S. , Apr. 2012, Molecular Pharmacology

Balance of older trekkers: data on alpine accidents and performance as assessed using a video game machine. , Kimura M, Tobe M, Suto T, Narahara S, Yamada M, Aso C, Takazawa T, Baba Y, Saito S. , May 2012, The American Journal of Emergency Medicine

Three suspected cases of sugammadex-induced anaphylactic shock, Takazawa, Tomonori; Tomita, Yukinari; Yoshida, Nagahide; Tomioka, Akihiro; Horiuchi, Tatsuo; Nagata, Chie; Orihara, Masaki; Yamada, Makiko Hardy; Saito, Shigeru, Oct. 2014, BMC ANESTHESIOLOGY

Changes in intraocular pressure during surgery in the lateral decubitus position under sevoflurane and propofol anesthesia, Yamada, Makiko Hardy; Takazawa, Tomonori; Iriuchijima, Nobuhisa; Horiuchi, Tatsuo; Saito, Shigeru, Dec. 2016, JOURNAL OF CLINICAL MONITORING AND COMPUTING

Carbon dioxide exhalation temporarily increases during electroconvulsive therapy, SAKURAZAWA SHINOBU;SAITO SHIGERU;YAMADA MAKIKO;NISHIHARA FUMIO;GOTO FUMIO, Feb. 2006, 20, 1, 68, 70

Anesthetic management for clipping a giant basilar artery aneurysm with moderate hypothermia, extracorporeal circulation assistance, and propofol infusion., Yamada Makiko;Nishikawa Koichi;Kawahara Fuminori;Yoshikawa Daisuke;Saito Shigeru;Goto Fumio, Journal of neurosurgical anesthesiology, 15, 3

Preparation for Safer Super-Emergency Caesarean Sections： Basic Knowledge and Decisions for Anesthesia Management, OTAKA Maiko;YAMADA Makiko Hardy;HINOHARA Hiroshi;SAITO Shigeru, Jan. 2021, THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA, 41, 1, 66, 72

A case of withdrawal symptoms after long-term opioid use, FUJINO Kento;HIROKI Tadanao;MIEDA Rie;YAMADA Makiko Hardy;SEKIMOTO Kenichi;SAITO Shigeru, Mar. 2021, Journal of Japan Society of Pain Clinicians, 28, 3, 27, 30

Relationship between arterial oxygen saturation and heart rate variability at high altitudes., Saito Shigeru;Tanobe Kyoko;Yamada Makiko;Nishihara Fumio, The American journal of emergency medicine, 23, 1

Carbon dioxide exhalation temporarily increases during electroconvulsive therapy., Sakurazawa Shinobu;Saito Shigeru;Yamada Makiko;Nishihara Fumio;Goto Fumio, Journal of anesthesia, 20, 1

Peripheral circulation monitored by surface temperature and autonomic nervous function in hypobaric hypoxic environment: effects of submaximal exercise., Fukuda-Matsuda Eri;Yamada Makiko;Tanobe Kyoko;Saito Shigeru, International journal of environmental health research, 17, 1

オピオイドの過量投与として対処されていた細菌性髄膜炎による意識障害の一例, ;;;;;, Jun. 2017, 12, Suppl., S484

抗結核薬内服経過中に発生した多発関節炎の疼痛治療経験の一例, ;;;;, Jun. 2017, 24, 3, 389

臨床モニタリングに関する研究　セボフルランとプロポフォールによる麻酔下における側臥位手術中の眼圧変化(Changes in intraocular pressure during surgery in the lateral decubitus position under sevoflurane and propofol anesthesia), 山田 真紀子, Oct. 2018, 38, 6, S123

幻視や幻聴の精神症状が、心理的苦痛による解離性障害であった進行膵頭部癌の一例, ;;;, Jun. 2021, 16, Suppl., S289

オピオイド長期使用後に漸減したにもかかわらず退薬症状が生じた1例, ;;;;;, Mar. 2021, 28, 3, 27

がん治癒後もオピオイドが同様に使用されていた状態から、慢性疼痛としての薬物彫法へ対処した一症例, ;;, Jun. 2021, 28, プログラム号, O13

強オピオイド貼付薬の増量を機に発症したセロトニン症候群, ;;;;, Jun. 2021, 28, プログラム号, O25

Balance of older trekkers: data on alpine accidents and performance as assessed using a video game machine., Kimura Masafumi;Tobe Masaru;Suto Takashi;Narahara Soh;Yamada Makiko;Aso Chizu;Takazawa Tomonori;Baba Yasuo;Saito Shigeru, May 2012, The American journal of emergency medicine, 30, 7

腸骨鼡径神経痛3例の検討, ;;;;;;;;;;, May 2020, 16, 3, 141

社会的ストレスが一因で慢性痛が遷延している1例, ;;;, Jun. 2022, 29, 6, 126

NSAIDs経皮吸収型製剤が有効であったがん疼痛3症例, ;;, Jun. 2022, 29, 6, 127

心理的背景によりオピオイドの過量からセロトニン症候群を発生した一例, ;;;;;;;, Jul. 2022, 17, Suppl., S.231

重粒子線治療後の有害事象に対し、長期的な緩和ケアアプローチを要した2症例, ;;;;;;;;, Jul. 2022, 17, Suppl., S.282

Modulation of pain threshold and glycinergic neurotransmission in mice with reduced expression of vesicular GABA transporter (VGAT), Yamada, Makiko;Nishikawa, Koichi;Kubo, Kazuhiro;Yanagawa, Yuchio;Saito, Shigeru, 2011, NEUROSCIENCE RESEARCH, 71, E156, E156

Balance of older trekkers: data on alpine accidents and performance as assessed using a video game machine, Kimura, Masafumi;Tobe, Masaru;Suto, Takashi;Narahara, Soh;Yamada, Makiko;Aso, Chizu;Takazawa, Tomonori;Baba, Yasuo;Saito, Shigeru, 2012, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 30, 7, 1125, 1128

オピオイドの過量投与として対処されていた細菌性髄膜炎による意識障害の一例, ;;;, Jun. 2019, 14, Suppl., S270

抗結核薬内服経過中に発生した多発関節炎の疼痛治療経験の一例, ;, Jun. 2019, 26, 3, P2

麻酔科医と協働するMDRPU減少への取り組み, ;;;;, Oct. 2019, 39, 6, S229

血液検査及び画像検査で異常を指摘されなかった下腹部痛の3症例, ;;;;;;;;;;, Nov. 2019, 15, 6, 567

腸骨鼡径神経痛3例の検討, ;;;;;;;;;;, May 2020, 16, 3, 141

術中肢位の影響によると思われる麻酔覚醒後に激しい肘関節部痛を訴えた一例, ;;;;;, Oct. 2020, 40, 6, S281

精神心理的背景へ配慮し、放射線治療とオピオイドスイッチングにより疼痛コントロールを得たがん性疼痛症例, ;;;, Oct. 2020, 40, 6, S362

高用量オキシコドン徐放錠内服時におけるオピオイドスイッチングとして、タペンタドールが有効であった2症例, ;;;, Aug. 2020, 15, Suppl., S333

カテゴリー1緊急帝王切開術　超緊急帝王切開とは?麻酔科医が知っておくべき最低限の知識, ;;;, Jan. 2021, 41, 1, 66

心理的背景によりオピオイドの過量からセロトニン症候群を発生した一例, ;;;;;;;, Jul. 2022, 17, Suppl., S.231

重粒子線治療後の有害事象に対し、長期的な緩和ケアアプローチを要した2症例, ;;;;;;;;, Jul. 2022, 17, Suppl., S.282

電撃症における疼痛マネジメントの一症例, ;;, Oct. 2022, 42, 6, S189

社会的ストレスが一因で慢性痛が遷延している1例, ;;;, Jun. 2022, 29, 6, 126

NSAIDs経皮吸収型製剤が有効であったがん疼痛3症例, ;;, Jun. 2022, 29, 6, 127

骨転移治療のための診療科間協力体制の構築　骨転移治療における緩和的アプローチ, ;, Oct. 2022, 60回, OWS24

妊娠後期の腹部痛に対して持続硬膜外麻酔による疼痛管理を施行した1症例, ;;;, Jun. 2023, 30, 6, 143

がんサバイバーの慢性疼痛に対するグループリハビリテーションプログラムの一例, ;;;;;;;;;;;, Jun. 2023, 18, Suppl., S263

頸椎症性神経根症に対して超音波ガイド下ステロイド添加神経ブロックおよびパルス高周波法が奏功した一例, ;;;;;, Jun. 2023, 30, プログラム号, 318

妊娠後期の腹部痛に対して持続硬膜外麻酔による疼痛管理を施行した1症例, ;;;, Jun. 2023, 30, 6, 143

がんサバイバーの慢性疼痛に対するグループリハビリテーションプログラムの一例, ;;;;;;;;;;;, Jun. 2023, 18, Suppl., S263

頸椎症性神経根症に対して超音波ガイド下ステロイド添加神経ブロックおよびパルス高周波法が奏功した一例, ;;;;;, Jun. 2023, 30, プログラム号, 318

クラウド会議システムを用いた緩和ケア地域連携カンファレンスの取り組み, ;;;;, Dec. 2023, 18, Suppl._Kanto-Koshinetsu, S996

A novel bFGF-GH injection therapy for two patients with severe ischemic limb pain, Naomi Ito,Shigeru Saito,Makiko Hardy Yamada,Shiro Koizuka,Hideaki Obata,Koichi Nishikawa,Yasuhiko Tabata, Nov. 2008, JOURNAL OF ANESTHESIA, 22, 4, 449, 452

Oxygen inhalation using an oxygen concentrator in a low-pressure environment outside of a hospital, Hirokazu Sakaue,Takashi Suto,Masafumi Kimura,Sou Narahara,Tomonobu Sato,Masaru Tobe,Chizu Aso,Toshie Kakinuma,Makiko Hardy-Yamada,Shigeru Saito, Nov. 2008, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 26, 9, 981, 984

Oxygen inhalation using an oxygen concentrator in a low-pressure environment outside of a hospital, Hirokazu Sakaue,Takashi Suto,Masafumi Kimura,Sou Narahara,Tomonobu Sato,Masaru Tobe,Chizu Aso,Toshie Kakinuma,Makiko Hardy-Yamada,Shigeru Saito, Nov. 2008, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 26, 9, 981, 984

Altered Responses to Propofol, but Not Ketamine, in Mice Deficient in the 65-Kilodalton Isoform of Glutamate Decarboxylase, Kazuhiro Kubo,Koichi Nishikawa,Makiko Hardy-Yamada,Junko Ishizeki,Yuchio Yanagawa,Shigeru Saito, May 2009, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 329, 2, 592, 599

Thermal Hyperalgesia via Supraspinal Mechanisms in Mice Lacking Glutamate Decarboxylase 65, Kazuhiro Kubo,Koichi Nishikawa,Junko Ishizeki,Makiko Hardy-Yamada,Yuchio Yanagawa,Shigeru Saito, Oct. 2009, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 331, 1, 162, 169

Thermal Hyperalgesia via Supraspinal Mechanisms in Mice Lacking Glutamate Decarboxylase 65, Kazuhiro Kubo,Koichi Nishikawa,Junko Ishizeki,Makiko Hardy-Yamada,Yuchio Yanagawa,Shigeru Saito, Oct. 2009, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 331, 1, 162, 169

Peripheral circulation monitored by surface temperature and autonomic nervous function in hypobaric hypoxic environment: Effects of submaximal exercise, Eri Fukuda-Matsuda,Maiuko Yamada,Kyoko Tanobe,Shigeru Saito, Feb. 2007, INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH, 17, 1, 53, 60

Peripheral circulation monitored by surface temperature and autonomic nervous function in hypobaric hypoxic environment: Effects of submaximal exercise, Eri Fukuda-Matsuda,Maiuko Yamada,Kyoko Tanobe,Shigeru Saito, Feb. 2007, INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH, 17, 1, 53, 60

Relationship between arterial oxygen saturation and heart rate variability at high attitudes, S Saito,K Tanobe,M Yamada,F Nishihara, Jan. 2005, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 23, 1, 8, 12

Relationship between arterial oxygen saturation and heart rate variability at high attitudes, S Saito,K Tanobe,M Yamada,F Nishihara, Jan. 2005, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 23, 1, 8, 12

Impaired Glycinergic Synaptic Transmission and Enhanced Inflammatory Pain in Mice with Reduced Expression of Vesicular GABA Transporter (VGAT), Makiko Hardy Yamada,Koichi Nishikawa,Kazuhiro Kubo,Yuchio Yanagawa,Shigeru Saito, Apr. 2012, MOLECULAR PHARMACOLOGY, 81, 4, 610, 619

Impaired Glycinergic Synaptic Transmission and Enhanced Inflammatory Pain in Mice with Reduced Expression of Vesicular GABA Transporter (VGAT), Makiko Hardy Yamada,Koichi Nishikawa,Kazuhiro Kubo,Yuchio Yanagawa,Shigeru Saito, Apr. 2012, MOLECULAR PHARMACOLOGY, 81, 4, 610, 619

Balance of older trekkers: data on alpine accidents and performance as assessed using a video game machine, Masafumi Kimura,Masaru Tobe,Takashi Suto,Soh Narahara,Makiko Yamada,Chizu Aso,Tomonori Takazawa,Yasuo Baba,Shigeru Saito, Sep. 2012, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 30, 7, 1125, 1128

Balance of older trekkers: data on alpine accidents and performance as assessed using a video game machine, Masafumi Kimura,Masaru Tobe,Takashi Suto,Soh Narahara,Makiko Yamada,Chizu Aso,Tomonori Takazawa,Yasuo Baba,Shigeru Saito, Sep. 2012, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 30, 7, 1125, 1128

Anesthetic management for clipping a giant basilar artery aneurysm with moderate hypothermia, extracorporeal circulation assistance, and propofol infusion, M Yamada,K Nishikawa,F Kawahara,D Yoshikawa,S Saito,F Goto, Jul. 2003, JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY, 15, 3, 274, 277

Anesthetic management for clipping a giant basilar artery aneurysm with moderate hypothermia, extracorporeal circulation assistance, and propofol infusion, M Yamada,K Nishikawa,F Kawahara,D Yoshikawa,S Saito,F Goto, Jul. 2003, JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY, 15, 3, 274, 277

Changes in intraocular pressure during surgery in the lateral decubitus position under sevoflurane and propofol anesthesia, Makiko Hardy Yamada,Tomonori Takazawa,Nobuhisa Iriuchijima,Tatsuo Horiuchi,Shigeru Saito, Dec. 2016, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 30, 6, 869, 874

Changes in intraocular pressure during surgery in the lateral decubitus position under sevoflurane and propofol anesthesia, Makiko Hardy Yamada,Tomonori Takazawa,Nobuhisa Iriuchijima,Tatsuo Horiuchi,Shigeru Saito, Dec. 2016, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 30, 6, 869, 874

Three suspected cases of sugammadex-induced anaphylactic shock, Tomonori Takazawa,Yukinari Tomita,Nagahide Yoshida,Akihiro Tomioka,Tatsuo Horiuchi,Chie Nagata,Masaki Orihara,Makiko Hardy Yamada,Shigeru Saito, Oct. 2014, BMC ANESTHESIOLOGY, 14, 92

Three suspected cases of sugammadex-induced anaphylactic shock, Tomonori Takazawa,Yukinari Tomita,Nagahide Yoshida,Akihiro Tomioka,Tatsuo Horiuchi,Chie Nagata,Masaki Orihara,Makiko Hardy Yamada,Shigeru Saito, Oct. 2014, BMC ANESTHESIOLOGY, 14, 92

Carbon dioxide exhalation temporarily increases during electroconvulsive therapy., Sakurazawa S,Saito S,Yamada M,Nishihara F,Goto F, 2006, 20, 1, 68, 70

Role of presynaptic mechanisms in propofol-induced facilitation of gamma-amino butyric acid (GABA)-mediated inhibitory neurotransmission., Nishikawa K,Kubo K,Yamada M,Ishizeki J, 2007, 56, 108, 112

Carbon dioxide exhalation temporarily increases during electroconvulsive therapy., Sakurazawa S,Saito S,Yamada M,Nishihara F,Goto F, 2006, Journal of Anesthesia, 20, 1, 68, 70

Role of presynaptic mechanisms in propofol-induced facilitation of gamma-amino butyric acid (GABA)-mediated inhibitory neurotransmission., Nishikawa K,Kubo K,Yamada M,Ishizeki J, 2007, Masui, 56, 108, 112

A novel bFGF-GH injection therapy for two patients with severe ischemic limb pain., Ito N,Saito S,Yamada MH,Koizuka S,Obata H,Nishikawa K,Tabata Y, 2008, 22, 4, 449, 452

Altered responses to propofol, but not ketamine, in mice deficient in the 65-kilodalton isoform of glutamate decarboxylase., Kubo K,Nishikawa K,Hardy-Yamada M,Ishizeki J,Yanagawa Y,Saito S, 2009, The Journal of Pharmacology and Experimental Therapeutics, 329, 2, 592, 599

Analysis of the inhibitory nerve system on spinal cord, Grant-in-Aid for Scientific Research, 2007, Competitive research funding

2007, Competitive research funding