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TOMITA Haruyoshi
Bacteriology
Professor
Last Updated :2025/03/27

Researcher Profile and Settings

Researcher

  • Name

    TOMITA Haruyoshi

Profile and Settings

  • Name

    Tomita, Haruyoshi

Foreign language

  • Use in presentation

    English

  • Use in publication

    English

Affiliation

  • Gunma University, Associate Professor

Education

  • 1996, Gunma University, Graduate School, Division of Medicine
  • 1989, Yamanashi Medical University, Faculty of Medicine
  • 1996, Gunma University
  • 1989

Degree

  • Ph.D(medicine)

Association Memberships

  • American Society for Microbiology (ASM)

Research Experience

  • 1996, 2003, Research Assistant, Department of Microbiology, Gunma University School of Medicine
  • 1997, 1999, Postdoctral Research Fellow, Michigan University
  • 2004, 2009, Lecturer, Department of Bacteriology and Bacterial Infection Control, Gunma University Graduate School of Medicine
  • 2009, - Associate Professor,
  • Department of Bacteriology,
  • Gunma University Graduate School of Medicine
  • 1996, 2003, Gunma University, Faculty of Medicine
  • 1997, 1999
  • 2004, 2009, Gunma University, Graduate School of Medicine
  • 2009

Research Activities

Research Areas

  • Life sciences, Bacteriology

Research Interests

  • Molecular GeneticsBacterial PathogenesisBacterial Drug ResistanceBacteriocinConjugation

Research Themes

  • Genetic Analyses of Bacteriocin of Enterococcus faecalis, E.faecalis,Bacteriocin,Plasmid, Institutional Collaboration, 1992, -, Bacteriology (including Mycology), Grant-in-Aid for Scientific Research
  • study of highly conjugative plasmids in enterococci, enterococci, conjugative plasmid, International Collaboration, 1993, -, Bacteriology (including Mycology), Molecular Biology, Grant-in-Aid for Scientific Research
  • study of enterococcaal adhesin, enterococci, adhesin, Institutional Collaboration, 1999, -, Bacteriology (including Mycology), Grant-in-Aid for Scientific Research
  • study of bacterial drug resistances, bacterial drug resistance, Institutional Collaboration, 1994, -, Bacteriology (including Mycology), Grant-in-Aid for Scientific Research
  • study of the ultraviolet-rays resistance (UVr) of enterococci, ultraviolet rays, enterococci, Institutional Collaboration, 2001, -, Bacteriology (including Mycology), Grant-in-Aid for Scientific Research

Published Papers

  • Tissue-specific adherent Enterococcus faecalis strains that show highly efficient adhesion to human bladder carcinoma T24 cells also adhere to extracellular matrix proteins., TOMITA HARUYOSHI ／ IKE YASUYOSHI, Oct. 2004, Infection and Immunity
  • Cloning and Genetic Organization of the Bacteriocin 31 Determinant Encoded on the Enterococcus faecalis Pheromone-Responsive Conjugative Plasmid pYI17., TOMITA HARUYOSHI ／ FUJIMOTO SHUHEI ／ TANIMOTO KOICHI ／ IKE YASUYOSHI, Jun. 1996, Journal of Bacteriology
  • Cloning and Genetic and Sequence Analyses of the Bacteriocin 21 Determinant Encoded on the Enterococcus faecalis Pheromone-Responsive Conjugative Plasmid pPD1., TOMITA HARUYOSHI ／ FUJIMOTO SHUHEI ／ TANIMOTO KOICHI ／ IKE YASUYOSHI, Dec. 1997, Journal of Bacteriology
  • Highly conjugative pMG1-like plasmids carrying Tn1546-like transposons that encode vancomycin resistance in Enterococcus faecium., Haruyoshi Tomita/ Koichi Tanimoto /Yasuyoshi Ike / Kyoko Morinaga / S. Hayamkawa / K. Ezaki / H. Ohshima, Dec. 2003, Journal of Bacteriology
  • A pAD1-Encoded Small RNA Molecule, mD, Negatively Regulates Enterococcus faecalis Pheromone Response by Enhancing Transcription Termination, TOMITA HARUYOSHI ／ Clewell DB, Feb. 2000, Journal of Bacteriology
  • Possible connection between a widely disseminated conjugative gentamicin resistance (pMG1-like) plasmid and the emergence of vancomycin resistance in Enterococcus faecium., Tomita H, Pierson C, Lim SK, Clewell DB, Ike Y, Sep. 2002, Journal of Clinical Microbiology
  • Genetic analysis of transfer-related regions of the vancomycin resistance Enterococcus conjugative plasmid pHTbeta: identification of oriT and a putative relaxase gene, TOMITA HARUYOSHI / IKE YASUYOSHI, Nov. 2005, Journal of Bacteriology
  • Cloning and genetic analyses of the bacteriocin 41 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pYI14: a novel bactereiocin complemented by two extracellular components (lysin and activator), Tomita H, Kamei E, Ike Y, Mar. 2008, Journal of Bacteriology
  • Genetic analysis of the Enterococcus vancomycin resistance conjugative plasmid pHTbeta: identification of the region involved in cell aggregation and traB, a key regulator gene for plasmid transfer and cell aggregation., Tomita H and Ike Y, Dec. 2008, Journal of Bacteriology
  • Genetic organization and mode of action of a novel bacteriocin, bacteriocin 51: determinant of VanA-type vancomycin-resistant Enterococcus faecium., Yamashita H, Tomita H, Inoue Y, Ike Y, Sep. 2011, Antimicrob Agents Chemother
  • Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation., Tanimoto K, Tomita H, Fujimoto S, Okuzumi K, Ike Y, Oct. 2008, Antimicrob Agents Chemother
  • Isolation of VanB-type Enterococcus faecdalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, encoding VanB-type vancomycin resistance and an Bac41-type bacteriocin, and pMG2201, encoding erythromycin resistance and cytolycin (Hly/Bac)., Zheng B, Tomita H, Inoue T, Ike Y, Feb. 2009, Antimicrob Agents Chemother
  • 腸球菌の高頻度接合伝達性プラスミド, 富田治芳, Dec. 2009, 64, 2-4, 343-355
  • Assessment of antibiotic resistance in probiotic strain Lactobacillus brevis KB290., Fukao M, TOmita H, Yakabe T, Ike Y, Yajima N., Sep. 2009, J Food Prot
  • Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010., LiY, Tomita H, Lv Y, Liu J, Xue F, Zheng B, Ike Y, Jan. 2011, J Appl Microbiol
  • Identifaication of VanN-type vancomycin resistance in an Enterococcus faecium isolate from chicken meat in Japan., Nomura T, Tanimoto K, Shibayama K, Arakawa Y, Fujimoto S, Ike Y, Tomita H., Dec. 2012, Antimicrob Agents Chemother
  • Genetic shifts in methicillin-resistant Staphylococcus aureus epidemic clones and toxin gene profiles in Japan: comparative analysis among pre-epidemic, epidemic and post-epidemic phases, Osaka, Shunsuke; Okuzumi, Katsuko; Koide, Shota; Tamai, Kiyoko; Sato, Tomoaki; Tanimoto, Koichi; Tomita, Haruyoshi; Suzuki, Masahiro; Nagano, Yukiko; Shibayama, Keigo; Arakawa, Yoshichika; Nagano, Noriyuki, 2018, JOURNAL OF MEDICAL MICROBIOLOGY
    DOI
  • New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species, Nomura, Takahiro; Hashimoto, Yusuke; Kurushima, Jun; Hirakawa, Hidetada; Tanimoto, Koichi; Zheng, Bo; Ruan, Genjie; Xue, Feng; Liu, Jian; Hisatsune, Junzo; Sugai, Motoyuki; Tomita, Haruyoshi, 2018, JOURNAL OF MICROBIOLOGICAL METHODS
    DOI
  • Postoperative Enterococcus faecalis endophthalmitis: virulence factors leading to poor visual outcome, Todokoro, Daisuke; Suzuki, Takashi; Kobayakawa, Shinichiro; Tomita, Haruyoshi; Ohashi, Yuichi; Akiyama, Hideo, 2017, JAPANESE JOURNAL OF OPHTHALMOLOGY
    DOI
  • Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions, Kurabayashi, Kumiko; Tanimoto, Koichi; Tomita, Haruyoshi; Hirakawa, Hidetada, 2017, FRONTIERS IN MICROBIOLOGY
    DOI
  • Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli, Kurabayashi, Kumiko; Agata, Tomohiro; Asano, Hirofumi; Tomita, Haruyoshi; Hirakawa, Hidetada, Nov. 2016, INFECTION AND IMMUNITY
    DOI
  • Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains, Kurushima, Jun; Ike, Yasuyoshi; Tomita, Haruyoshi, 2016, JOURNAL OF BACTERIOLOGY
    DOI
  • Rule of Hydrophobicity/Hydrophilicity Balance in Membrane-Disrupting Antimicrobial Activity of Polyalkylamino Cyclodextrins Synthesized via Click Chemistry, Yamamura, Hatsuo; Miyagawa, Atsushi; Sugiyama, Hiroki; Murata, Kensuke; Mabuti, Takahiro; Mitsuhashi, Ryogo; Hagiwara, Tatsuya; Nonaka, Miho; Tanimoto, Koichi; Tomita, Haruyoshi, 2016, CHEMISTRYSELECT
    DOI
  • Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis, Taniguchi, Tomoyo; Miyauchi, Eiji; Nakamura, Shota; Hirai, Makoto; Suzue, Kazutomo; Imai, Takashi; Nomura, Takahiro; Handa, Tadashi; Okada, Hiroko; Shimokawa, Chikako; Onishi, Risa; Olia, Alex; Hirata, Jun; Tomita, Haruyoshi; Ohno, Hiroshi; Horii, Toshihiro; Hisaeda, Hajime, Oct. 2015, SCIENTIFIC REPORTS
    DOI
  • Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions, Kurabayashi, Kumiko; Tanimoto, Koichi; Fueki, Shinobu; Tomita, Haruyoshi; Hirakawa, Hidetada, Oct. 2015, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    DOI
  • Identification of a Second Two-Component Signal Transduction System That Controls Fosfomycin Tolerance and Glycerol-3-Phosphate Uptake, Kurabayashi, Kumiko; Hirakawa, Yuko; Tanimoto, Koichi; Tomita, Haruyoshi; Hirakawa, Hidetada, 2015, JOURNAL OF BACTERIOLOGY
    DOI
  • Bacteriocin Protein BacL(1) of Enterococcus faecalis Targets Cell Division Loci and Specifically Recognizes L-Ala(2)-Cross-Bridged Peptidoglycan, Kurushima, Jun; Nakane, Daisuke; Nishizaka, Takayuki; Tomita, Haruyoshi, 2015, JOURNAL OF BACTERIOLOGY
    DOI
  • Nosocomial infection caused by vancomycin-susceptible multidrug-resistant Enterococcus faecalis over a long period in a university hospital in Japan, Kudo, Michiaki; Nomura, Takahiro; Yomoda, Sachie; Tanimoto, Koichi; Tomita, Haruyoshi, Nov. 2014, MICROBIOLOGY AND IMMUNOLOGY
    DOI
  • Role of the CpxAR Two-Component Signal Transduction System in Control of Fosfomycin Resistance and Carbon Substrate Uptake, Kurabayashi, Kumiko; Hirakawa, Yuko; Tanimoto, Koichi; Tomita, Haruyoshi; Hirakawa, Hidetada, 2014, JOURNAL OF BACTERIOLOGY
    DOI
  • Bacteriocin Protein BacL(1) of Enterococcus faecalis Is a Peptidoglycan D-Isoglutamyl-L-lysine Endopeptidase, Kurushima, Jun; Hayashi, Ikue; Sugai, Motoyuki; Tomita, Haruyoshi, Dec. 2013, JOURNAL OF BIOLOGICAL CHEMISTRY
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  • Identification of Novel Genes Responsible for Overexpression of ampC in Pseudomonas aeruginosa PAO1, Tsutsumi, Yuko; Tomita, Haruyoshi; Tanimoto, Koichi, Dec. 2013, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    DOI
  • Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance, Hirakawa, Hidetada; Tomita, Haruyoshi, 2013, FRONTIERS IN MICROBIOLOGY
    DOI
  • First VanD-type vancomycin-resistant Enterococcus raffinosus isolate, Tanimoto, Koichi;Nomura, Takahiro;Maruyama, Hideyuki;Tomita, Haruyoshi;Shibata, Naohiro;Arakawa, Yoshichika;Ike, Yasuyoshi, 2006, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 50, 11, 3966, 3967
    DOI
  • Genetic analysis of bacteriocin 43 of vancomycin-resistant Enterococcus faecium, Todokoro, Daisuke;Tomita, Haruyoshi;Inoue, Takako;Ike, Yasuyoshi, 2006, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72, 11, 6955, 6964
    DOI
  • Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from mainland China, Zheng, Bo;Tomita, Haruyoshi;Xiao, Yong Hong;Wang, Shan;Li, Yun;Ike, Yasuyoshi, 2007, JOURNAL OF CLINICAL MICROBIOLOGY, 45, 9, 2813, 2818
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  • Assessment of Antibiotic Resistance in Probiotic Strain Lactobacillus brevis KB290, Fukao, Masanori;Tomita, Haruyoshi;Yakabe, Takafumi;Nomura, Takahiro;Ike, Yasuyoshi;Yajima, Nobuhiro, 2009, JOURNAL OF FOOD PROTECTION, 72, 9, 1923, 1929
  • Genetic Organization and Mode of Action of a Novel Bacteriocin, Bacteriocin 51: Determinant of VanA-Type Vancomycin-Resistant Enterococcus faecium, Yamashita, Hitoshi;Tomita, Haruyoshi;Inoue, Takako;Ike, Yasuyoshi, 2011, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55, 9, 4352, 4360
    DOI
  • Identification of VanN-Type Vancomycin Resistance in an Enterococcus faecium Isolate from Chicken Meat in Japan, Nomura, Takahiro;Tanimoto, Koichi;Shibayama, Keigo;Arakawa, Yoshichika;Fujimoto, Shuhei;Ike, Yasuyoshi;Tomita, Haruyoshi, 2012, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56, 12, 6389, 6392
    DOI
  • Effect of Sub-MICs of Macrolides on the Sensitivity of Pseudomonas aeruginosa to Nitrosative Stress: Effectiveness against P. aeruginosa with and without Multidrug Resistance, Shimizu, Takeshi;Miyoshi-Akiyama, Tohru;Ogura, Kohei;Murata, Shota;Ishige, Shota;Kai, Kiyohiro;Mitsutsuka, Konosuke;Tomita, Haruyoshi;Tanimoto, Koichi;Matsumoto, Akio, 2020, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 64, 10
    DOI
  • Identification of Novel Genes Responsible for Overexpression of ampC in Pseudomonas aeruginosa PAO1, Tsutsumi, Yuko;Tomita, Haruyoshi;Tanimoto, Koichi, 2013, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 57, 12, 5987, 5993
    DOI
  • Nosocomial infection caused by vancomycin-susceptible multidrug-resistant Enterococcus faecalis over a long period in a university hospital in Japan, Kudo, Michiaki;Nomura, Takahiro;Yomoda, Sachie;Tanimoto, Koichi;Tomita, Haruyoshi, 2014, MICROBIOLOGY AND IMMUNOLOGY, 58, 11, 607, 614
    DOI
  • Bacteriocin Protein BacL(1) of Enterococcus faecalis Targets Cell Division Loci and Specifically Recognizes L-Ala(2)-Cross-Bridged Peptidoglycan, Kurushima, Jun;Nakane, Daisuke;Nishizaka, Takayuki;Tomita, Haruyoshi, 2015, JOURNAL OF BACTERIOLOGY, 197, 2, 286, 295
    DOI
  • Identification of a Second Two-Component Signal Transduction System That Controls Fosfomycin Tolerance and Glycerol-3-Phosphate Uptake, Kurabayashi, Kumiko;Hirakawa, Yuko;Tanimoto, Koichi;Tomita, Haruyoshi;Hirakawa, Hidetada, 2015, JOURNAL OF BACTERIOLOGY, 197, 5, 861, 871
    DOI
  • Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis, Taniguchi, Tomoyo;Miyauchi, Eiji;Nakamura, Shota;Hirai, Makoto;Suzue, Kazutomo;Imai, Takashi;Nomura, Takahiro;Handa, Tadashi;Okada, Hiroko;Shimokawa, Chikako;Onishi, Risa;Olia, Alex;Hirata, Jun;Tomita, Haruyoshi;Ohno, Hiroshi;Horii, Toshihiro;Hisaeda, Hajime, 2015, SCIENTIFIC REPORTS, 5
    DOI
  • Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions, Kurabayashi, Kumiko;Tanimoto, Koichi;Fueki, Shinobu;Tomita, Haruyoshi;Hirakawa, Hidetada, 2015, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59, 10, 6352, 6360
    DOI
  • Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains, Kurushima, Jun;Ike, Yasuyoshi;Tomita, Haruyoshi, 2016, JOURNAL OF BACTERIOLOGY, 198, 17, 2379, 2390
    DOI
  • Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli, Kurabayashi, Kumiko;Agata, Tomohiro;Asano, Hirofumi;Tomita, Haruyoshi;Hirakawa, Hidetada, 2016, INFECTION AND IMMUNITY, 84, 11, 3220, 3231
    DOI
  • Rule of Hydrophobicity/Hydrophilicity Balance in Membrane-Disrupting Antimicrobial Activity of Polyalkylamino Cyclodextrins Synthesized via Click Chemistry, Yamamura, Hatsuo;Miyagawa, Atsushi;Sugiyama, Hiroki;Murata, Kensuke;Mabuti, Takahiro;Mitsuhashi, Ryogo;Hagiwara, Tatsuya;Nonaka, Miho;Tanimoto, Koichi;Tomita, Haruyoshi, 2016, CHEMISTRYSELECT, 1, 3, 469, 472
    DOI
  • Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions, Kurabayashi, Kumiko;Tanimoto, Koichi;Tomita, Haruyoshi;Hirakawa, Hidetada, 2017, FRONTIERS IN MICROBIOLOGY, 8
    DOI
  • Postoperative Enterococcus faecalis endophthalmitis: virulence factors leading to poor visual outcome, Todokoro, Daisuke;Suzuki, Takashi;Kobayakawa, Shinichiro;Tomita, Haruyoshi;Ohashi, Yuichi;Akiyama, Hideo, 2017, JAPANESE JOURNAL OF OPHTHALMOLOGY, 61, 5, 408, 414
    DOI
  • New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species, Nomura, Takahiro;Hashimoto, Yusuke;Kurushima, Jun;Hirakawa, Hidetada;Tanimoto, Koichi;Zheng, Bo;Ruan, Genjie;Xue, Feng;Liu, Jian;Hisatsune, Junzo;Sugai, Motoyuki;Tomita, Haruyoshi, 2018, JOURNAL OF MICROBIOLOGICAL METHODS, 145, 69, 72
    DOI
  • Genetic shifts in methicillin-resistant Staphylococcus aureus epidemic clones and toxin gene profiles in Japan: comparative analysis among pre-epidemic, epidemic and post-epidemic phases, Osaka, Shunsuke;Okuzumi, Katsuko;Koide, Shota;Tamai, Kiyoko;Sato, Tomoaki;Tanimoto, Koichi;Tomita, Haruyoshi;Suzuki, Masahiro;Nagano, Yukiko;Shibayama, Keigo;Arakawa, Yoshichika;Nagano, Noriyuki, 2018, JOURNAL OF MEDICAL MICROBIOLOGY, 67, 3, 392, 399
    DOI
  • Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter, Hirakawa, Hidetada;Kurabayashi, Kumiko;Tanimoto, Koichi;Tomita, Haruyoshi, 2018, FRONTIERS IN MICROBIOLOGY, 9
    DOI
  • Genetic diversity and persistent colonization of Enterococcus faecalis on ocular surfaces, Todokoro, Daisuke;Eguchi, Hiroshi;Suzuki, Takashi;Suzuki, Motoo;Nakayama-Imaohji, Haruyuki;Kuwahara, Tomomi;Nomura, Takahiro;Tomita, Haruyoshi;Akiyama, Hideo, 2018, JAPANESE JOURNAL OF OPHTHALMOLOGY, 62, 6, 699, 705
    DOI
  • Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan, Hashimoto, Yusuke;Kurushima, Jun;Nomura, Takahiro;Tanimoto, Koichi;Tamai, Kiyoko;Yanagisawa, Hideji;Shirabe, Komei;Ike, Yasuyoshi;Tomita, Haruyoshi, 2018, BMC MICROBIOLOGY, 18
    DOI
  • Detection of mcr-1-mediated colistin resistance in E-coli isolate from imported chicken meat from Brazil, Chiba, Naoko;Tanimoto, Koichi;Hisatsune, Junzo;Sugai, Motoyuki;Shibayama, Keigo;Watanabe, Haruo;Tomita, Haruyoshi, 2019, JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 16, 249, 250
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  • The Tol-Pal System of Uropathogenic Escherichia coli Is Responsible for Optimal Internalization Into and Aggregation Within Bladder Epithelial Cells, Colonization of the Urinary Tract of Mice, and Bacterial Motility, Hirakawa, Hidetada;Suzue, Kazutomo;Kurabayashi, Kumiko;Tomita, Haruyoshi, 2019, FRONTIERS IN MICROBIOLOGY, 10
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  • Novel Multidrug-Resistant Enterococcal Mobile Linear Plasmid pELF1 Encoding vanA and vanM Gene Clusters From a Japanese Vancomycin-Resistant Enterococci Isolate, Hashimoto, Yusuke;Taniguchi, Makoto;Kazuma, Uesaka;Nomura, Takahiro;Hirakawa, Hidetada;Tanimoto, Koichi;Tamai, Kiyoko;Ruan, Genjie;Zheng, Bo;Tomita, Haruyoshi, 2019, FRONTIERS IN MICROBIOLOGY, 10
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  • Roles of CytR, an anti-activator of cyclic-AMP receptor protein (CRP) on flagellar expression and virulence in uropathogenic Escherichia coli, Hirakawa, Hidetada;Takita, Ayako;Kato, Mao;Mizumoto, Hanano;Tomita, Haruyoshi, 2020, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 521, 3, 555, 561
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  • First Report of the Local Spread of Vancomycin-Resistant Enterococci Ascribed to the Interspecies Transmission of a vanA Gene Cluster-Carrying Linear Plasmid, Hashimoto, Yusuke;Kita, Izumi;Suzuki, Masato;Hirakawa, Hidetada;Ohtaki, Hidetada;Tomita, Haruyoshi, 2020, MSPHERE, 5, 2
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  • Molecular pharmacology of ciclesonide against SARS-CoV-2, Kimura, Hirokazu;Kurusu, Hiromu;Sada, Mitsuru;Kurai, Daisuke;Murakami, Koichi;Kamitani, Wataru;Tomita, Haruyoshi;Katayama, Kazuhiko;Ryo, Akihide, 2020, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 146, 2, 330, 331
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  • Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli, Hirakawa, Hidetada;Suzue, Kazutomo;Takita, Ayako;Awazu, Chikako;Kurushima, Jun;Tomita, Haruyoshi, 2020, SCIENTIFIC REPORTS, 10, 1
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  • グリコペプチド薬, 富田 治芳;藤本 修平;麻 興華;野村 隆浩;池 康嘉, Nov. 2003, Nihon Naika Gakkai Zasshi, 92, 11, 2149, 2157
  • 本邦におけるVREの細菌学的特性, 富田 治芳;野村 隆浩;谷本 弘一;池 康嘉, Dec. 2003, 13, 4
  • Potency of Carbapenems for the Prevention of Carbapenem-Resistant Mutants of Pseudomonas aeruginosa : The High Potency of a New Carbapenem Doripenem, SAKYO Shihomi;TOMITA Haruyoshi;TANIMOTO Koichi;FUJIMOTO Shuhei;IKE Yasuyoshi, Apr. 2006, J Antibiot, 59, 4, 220, 228
  • Highly conjugative plasmids in enterococci, TOMITA Haruyoshi, Dec. 2009, Nippon Saikingaku Zasshi, 64, 2, 343, 355
  • 臨床分離腸球菌E. faeciumの薬剤耐性とGentamycin耐性伝達性プラスミドについて, 竹内 邦夫;富田 治芳;工藤 通明;桑野 博行;池 康嘉, Mar. 2002, Journal of Japan Surgical Society, 103, 0
  • 群馬大学医学部付属病院における腸球菌(E.faecalis)の薬剤耐性の検討, 工藤 通明;富田 治芳;竹内 邦夫;桑野 博行;池 康嘉, Mar. 2002, Journal of Japan Surgical Society, 103, 0
  • Possible connection between a widely disseminated conjugative gentamicin resistance (pMG1-like) plasmid and the emergence of vancomycin resistance in Enterococcus faecium., Tomita Haruyoshi;Pierson Carl;Lim Suk Kyung;Clewell Don B;Ike Yasuyoshi, Journal of clinical microbiology, 40, 9
    DOI
  • 食品によるバンコマイシン耐性腸球菌(VRE)のグローバルな伝播, 富田 治芳;小澤 良之;谷本 弘一;池 康嘉, 2001, Environmental Infections, 16, 1, 36a, 36a
  • Genetics of Enterococcal Bacteriocins, Tomita Haruyoshi, 2012, The Kitakanto Medical Journal, 62, 1, 71, 72
  • A new class of Acyl-homoserine lactone quorum sensing signals, HIRAKAWA Hidetada;TOMITA Haruyoshi, 2013, Nippon Saikingaku Zasshi, 68, 4, 325, 335
  • GENETIC ANALYSIS OF BACTERIOCIN AND CONJUGATION-RELATED GENES OF BACTERIOCIN PLASMID pPD1 IN ENTEROCOCCUS FAECALIS, WAKAMATSU ERI;TOMITA HARUYOSHI;FUJIMOTO SHUHEI;TANIMOTO KOICHI, 1995, The KITAKANTO Medical Journal, 45, 2, 139, 154
  • GENETIC ANALYSIS OF THE BACTERIOCIN DETERMINANT ENCODED ON A CONJUGATIVE PLASMID PYI17 (57.5kb) OF ENTEROCOCCUS FAECALIS YI17, TOMITA HARUYOSHI, 1996, The KITAKANTO Medical Journal, 46, 2, 89, 102
  • 食品によるバンコマイシン耐性腸球菌(VRE)のグローバルな伝播, 富田 治芳;小澤 良之;谷本 弘一;池 康嘉, 2001, Japanese Journal of Extra-Corporeal Technology, 16, 1, 36a, 36a
  • Isolation of Serratia fonticola producing FONA, a minor extended-spectrum β-lactamase (ESBL), from imported chicken meat in Japan, Tanimoto Koichi;Nomura Takahiro;Hashimoto Yusuke;Hirakawa Hidetada;Watanabe Haruo;Tomita Haruyoshi, 2020, Japanese Journal of Infectious Diseases
  • Isolation of Serratia fonticola Producing FONA, a Minor Extended-Spectrum β-Lactamase (ESBL), from Imported Chicken Meat in Japan, Tanimoto Koichi;Nomura Takahiro;Hashimoto Yusuke;Hirakawa Hidetada;Watanabe Haruo;Tomita Haruyoshi, 2021, Japanese Journal of Infectious Diseases, 74, 1, 79, 81
  • Highly conjugative pMG1-like plasmids carrying Tn1546-like transposons that encode vancomycin resistance in Enterococcus faecium., Tomita Haruyoshi;Tanimoto Koichi;Hayakawa Satoshi;Morinaga Kyoko;Ezaki Kohji;Oshima Hisaji;Ike Yasuyoshi, Journal of bacteriology, 185, 23
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  • Tissue-specific adherent Enterococcus faecalis strains that show highly efficient adhesion to human bladder carcinoma T24 cells also adhere to extracellular matrix proteins., Tomita Haruyoshi;Ike Yasuyoshi, Infection and immunity, 72, 10
    DOI
  • Drug resistance of Enterococcus faecium clinical isolates and the conjugative transfer of gentamicin and erythromycin resistance traits., Takeuchi Kunio;Tomita Haruyoshi;Fujimoto Shuhei;Kudo Michiaki;Kuwano Hiroyuki;Ike Yasuyoshi, FEMS microbiology letters, 243, 2
    DOI
  • Genetic analysis of transfer-related regions of the vancomycin resistance Enterococcus conjugative plasmid pHTbeta: identification of oriT and a putative relaxase gene., Tomita Haruyoshi;Ike Yasuyoshi, Journal of bacteriology, 187, 22
    DOI
  • Bac 32, a novel bacteriocin widely disseminated among clinical isolates of Enterococcus faecium., Inoue Takako;Tomita Haruyoshi;Ike Yasuyoshi, Antimicrobial agents and chemotherapy, 50, 4
    DOI
  • Potency of carbapenems for the prevention of carbapenem-resistant mutants of Pseudomonas aeruginosa: the high potency of a new carbapenem doripenem., Sakyo Shihomi;Tomita Haruyoshi;Tanimoto Koichi;Fujimoto Shuhei;Ike Yasuyoshi, The Journal of antibiotics, 59, 4
    DOI
  • Pheromone-responsive conjugative vancomycin resistance plasmids in Enterococcus faecalis isolates from humans and chicken feces., Lim Suk-Kyung;Tanimoto Koichi;Tomita Haruyoshi;Ike Yasuyoshi, Applied and environmental microbiology, 72, 10
    DOI
  • Genetic analysis of bacteriocin 43 of vancomycin-resistant Enterococcus faecium., Todokoro Daisuke;Tomita Haruyoshi;Inoue Takako;Ike Yasuyoshi, 21 Aug. 2006, Applied and environmental microbiology, 72, 11
    DOI
  • Molecular characterization of vancomycin-resistant enterococcus faecium isolates from mainland China., Zheng Bo;Tomita Haruyoshi;Xiao Yong Hong;Wang Shan;Li Yun;Ike Yasuyoshi, 18 Jul. 2007, Journal of clinical microbiology, 45, 9
    DOI
  • Cloning and genetic analyses of the bacteriocin 41 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pYI14: a novel bacteriocin complemented by two extracellular components (lysin and activator)., Tomita Haruyoshi;Kamei Elizabeth;Ike Yasuyoshi, 18 Jan. 2008, Journal of bacteriology, 190, 6
    DOI
  • Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation., Tanimoto Koichi;Tomita Haruyoshi;Fujimoto Shuhei;Okuzumi Katsuko;Ike Yasuyoshi, 11 Aug. 2008, Antimicrobial agents and chemotherapy, 52, 10
    DOI
  • Genetic analysis of the Enterococcus vancomycin resistance conjugative plasmid pHTbeta: identification of the region involved in cell aggregation and traB, a key regulator gene for plasmid transfer and cell aggregation., Tomita Haruyoshi;Ike Yasuyoshi, 03 Oct. 2008, Journal of bacteriology, 190, 23
    DOI
  • Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2201, encoding erythromycin resistance and cytolysin (Hly/Bac)., Zheng Bo;Tomita Haruyoshi;Inoue Takako;Ike Yasuyoshi, 24 Nov. 2008, Antimicrobial agents and chemotherapy, 53, 2
    DOI
  • [Highly conjugative plasmids in enterococci]., Tomita Haruyoshi, Nihon saikingaku zasshi. Japanese journal of bacteriology, 64, 2-4
    DOI
  • 【グローバル化時代の耐性菌感染症】バンコマイシン耐性腸球菌, ;;;;;, Jan. 2016, 60, 1, 68
  • 嫌気環境における大腸菌群のホスホマイシン輸送体発現制御メカニズムの解析, ;;;, May 2016, 64, Suppl.A, 206
  • 群馬県内の医療施設における主要菌の抗菌薬感受性について　JANISデータの統合による検討, ;;;;;;;;;;;;, Dec. 2015, 26, Suppl., 417
  • 群馬県内で分離されたAcinetobacter属菌について, ;;;, Dec. 2015, 26, Suppl., 426
  • 嫌気環境におけるホスホマイシン抗菌活性増大メカニズムの解析, ;;;, May 2016, 64, 3, 592
  • 【いま知っておきたい、感染症診療最新の動向】最近話題の耐性菌　今どうなっているの?　バンコマイシン耐性腸球菌(VRE), 富田 治芳, Jun. 2016, 104, 6, 705
  • 【感染症のtrends & topics 2017】薬剤耐性菌の動向と対策, 富田 治芳, Dec. 2016, 33, 12, 47
  • 日和見病原菌Enterococcus faecalisのプラスミドにコードされる溶菌酵素Bac41の作用機構, ;, Dec. 2015, 88回・38回, [2P0489]
  • 鉄欠乏環境における尿路病原性大腸菌(UPEC)の膀胱上皮細胞侵入とマイクロコロニー形成促進機構, ;;, Aug. 2016, 66, 3, 250
  • バイオフィルム感染症におけるパーシスタンス現象の解明と対策　鉄の恒常性破綻による尿路病原性大腸菌(UPEC)のバイオフィルム形成促進, ;;;, Feb. 2016, 71, 1, 42
  • 薬剤耐性の基礎研究　嫌気環境下におけるホスホマイシン抗菌活性増大メカニズムの解析, ;;;, Feb. 2016, 71, 1, 47
  • 低濃度VanB型バンコマイシン耐性を持つ腸球菌の臨床単離物の分析(Analysis of the clinical enterococcal isolates with low-level VanB-type vancomycin resistance), ;;;, Feb. 2016, 71, 1, 143
  • 2015年に日本で分離されたVanN型VREの解析, ;;;;, Feb. 2016, 71, 1, 146
  • Clostridium difficileの臨床分離株における分子疫学的解析, ;;, Feb. 2016, 71, 1, 160
  • 鉄欠乏環境における尿路病原性大腸菌(UPEC)の膀胱上皮細胞内マイクロコロニー形成と抗菌剤抵抗性増大機構, ;;, Jan. 2017, 65, 1, 101
  • 国内の医療機関にて分離されたVanB型バンコマイシン感受性腸球菌に関する分子生物学的研究, ;;, Jan. 2017, 65, 1, 109
  • VanB型バンコマイシン耐性遺伝子群を保持したバンコマイシン感受性腸球菌に関する研究, ;;;;, Feb. 2017, 72, 1, 138
  • 鶏肉由来リネゾリド低度耐性腸球菌株の解析, ;;;;, Feb. 2017, 72, 1, 140
  • 輸入鶏肉由来ESBL産生大腸菌の持つプラスミド伝達性コリスチン耐性遺伝子(Colistine resistance gene mcr-1 in an ESBL-producing E. coli isolated from imported chicken meat), ;;, Feb. 2017, 72, 1, 140
  • 鶏肉からのESBL、AmpC産生腸内細菌科細菌の分離と解析, ;;;;;, Feb. 2017, 72, 1, 141
  • 食肉由来腸球菌のバシトラシン耐性についての研究, ;;;;, Feb. 2017, 72, 1, 142
  • 【グローバル化・温暖化と感染症対策】多剤耐性菌感染症　バンコマイシン耐性腸球菌感染症, 富田 治芳, Dec. 2017, 70, 増刊, 2439
  • 尿路病原性大腸菌(Uropathogenic E.coli:UPEC)の膀胱上皮細胞内マイクロコロニー形成と運動性におけるペリプラズム局在蛋白TolBの機能解析, ;;, Aug. 2017, 67, 3, 275
  • アシネトバクター属菌におけるPOT法を用いた疫学解析の臨床的有用性, ;;;;;, Oct. 2017, 65, 補冊, 189
  • リネゾリド低感受性腸球菌の解析, ;;;;, Dec. 2017, 28, Suppl.1, 489
  • 国内2つの医療機関にて分離されたVanB型バンコマイシン感受性腸球菌に関する分子生物学的研究, ;;;;;, Dec. 2017, 28, Suppl.1, 489
  • 基礎からみたグラム陰性耐性菌による院内感染症, 富田 治芳, May 2018, 92, 3, 450
  • 基礎からみたグラム陰性耐性菌による院内感染症, 富田 治芳, May 2018, 66, 3, 442
  • 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染におけるペリプラズム局在蛋白質TolBの機能解析, ;;, May 2018, 66, 3, 452
  • 国内医療機関にて分離されたVanB型バンコマイシン感受性腸球菌に関する分子生物学的研究, ;;;;;, May 2018, 66, 3, 462
  • 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染におけるペリプラズム局在蛋白質TolBの役割, ;;, Feb. 2018, 73, 1, 103
  • 食肉由来の腸球菌におけるバシトラシン耐性についての研究, ;;;;;, Feb. 2018, 73, 1, 142
  • 輸入鶏肉由来大腸菌の持つプラスミド伝達性コリスチン耐性遺伝子(Colistin resistance gene mcr-1 in an E. coli isolated from imported chicken meat), ;;, Feb. 2018, 73, 1, 147
  • 2017年に日本で分離されたVanN型VREの解析, ;;, Feb. 2018, 73, 1, 147
  • 鶏肉検体からのESBL,AmpC産生腸内細菌科細菌の分離と解析, ;;;;, Feb. 2018, 73, 1, 149
  • 国内2つの医療機関にて分離されたVanB型バンコマイシン感受性腸球菌に関する分子生物学的研究, ;;;;;;, Feb. 2018, 73, 1, 151
  • 尿路病原性大腸菌(UPEC)の膀胱上皮細胞内バイオフィルム形成と鞭毛形成因子TolBの機能解析, ;, Jul. 2018, 32回, 29
  • 国内で分離されたVanD型バンコマイシン耐性E.faeciumに関する分子遺伝学的解析, ;;;;, Dec. 2018, 29, Suppl.1, 397
  • 群馬県内で分離されたAcinetobacter属菌について, ;;;;, Dec. 2018, 29, Suppl.1, 400
  • 国内医療機関の入院患者より分離された、非常に稀なVanD型バンコマイシン耐性E.faeciumに関する分子生物学的解析, ;;;, Jan. 2019, 67, 1, 119
  • 嫌気環境における緑膿菌のホスホマイシンに対する感受性増大機構の解析, ;;, Jan. 2019, 67, 1, 121
  • 尿路病原性大腸菌(UPEC)の膀胱上皮細胞内バイオフィルム形成と鞭毛形成因子TolBの機能解析, ;, May 2019, 32, 33
  • 尿路病原性大腸菌(UPEC)のマイクロコロニー形成と鞭毛発現抑制因子CytRの解析, ;, Mar. 2019, 74, 1, 87
  • AMRの観点から薬剤耐性菌感染症に関するtranslational researchを考える　バイオフィルムを標的とした薬剤耐性大腸菌感染症に対する新たな治療戦略創出のためのアプローチ, ;, Mar. 2019, 93, 臨増, 307
  • 耐性菌感染症の治療　耐性菌感染症の治療　基礎の立場から, 富田 治芳, Mar. 2020, 68, 2, 240
  • 経口吸着炭AST-120による大腸菌の薬剤耐性と病原性抑制効果の検討, ;, Mar. 2020, 68, 2, 302
  • 国内医療機関より分離されたVanA型とVanM型の2つのバンコマイシン耐性遺伝子群を保有するVREに関する分子生物学的研究, ;;;, Mar. 2020, 68, 2, 302
  • 国内医療機関より分離されたVanA型とVanM型の2つのバンコマイシン耐性遺伝子群を保有する腸球菌の線状プラスミドに関する分子生物学的研究, ;;;, Dec. 2019, 30, Suppl.1, 236
  • リネゾリドに対して低感受性を示す腸球菌の解析, ;;;;;;, Dec. 2019, 30, Suppl.1, 290
  • 尿路病原性大腸菌(uropathogenic E.coli:UPEC)の病原性発現に関与する二成分制御系の解析, ;;;, Aug. 2019, 69, 3, 304
  • 耐性菌感染症の治療　基礎の立場から, 富田 治芳, Mar. 2020, 94, 2, 214
  • 鶏肉より分離したリネゾリドに対して低度耐性を示す腸球菌の解析, ;;;, Jan. 2020, 75, 1, 106
  • 輸入トリ肉から分離されたFONA産生Serratia fonticola, ;;;;, Jan. 2020, 75, 1, 111
  • 経口吸着炭AST-120による大腸菌の薬剤耐性と病原性抑制, ;;;, Jan. 2020, 75, 1, 147
  • VanA/M型の2つのバンコマイシン耐性遺伝子群を保有する腸球菌の線状プラスミドに関する分子生物学的研究, ;;;;, Jan. 2020, 75, 1, 148
  • プラスミド性コリスチン耐性菌はヒトの健康に対するハザードか?　世界の視点で考えるコリスチン耐性, 富田 治芳, Mar. 2020, 94, 臨増, 233
  • Genetic organization and mode of action of a novel bacteriocin, bacteriocin 51: determinant of VanA-type vancomycin-resistant Enterococcus faecium., Yamashita Hitoshi;Tomita Haruyoshi;Inoue Takako;Ike Yasuyoshi, 27 Jun. 2011, Antimicrobial agents and chemotherapy, 55, 9
    DOI
  • Identification of VanN-type vancomycin resistance in an Enterococcus faecium isolate from chicken meat in Japan., Nomura Takahiro;Tanimoto Koichi;Shibayama Keigo;Arakawa Yoshichika;Fujimoto Shuhei;Ike Yasuyoshi;Tomita Haruyoshi, 24 Sep. 2012, Antimicrobial agents and chemotherapy, 56, 12
    DOI
  • Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance., Hirakawa Hidetada;Tomita Haruyoshi, 13 May 2013, Frontiers in microbiology, 4
    DOI
  • Role of the CpxAR two-component signal transduction system in control of fosfomycin resistance and carbon substrate uptake., Kurabayashi Kumiko;Hirakawa Yuko;Tanimoto Koichi;Tomita Haruyoshi;Hirakawa Hidetada, 25 Oct. 2013, Journal of bacteriology, 196, 2
    DOI
  • [New class of Acyl-homoserine lactone quorum sensing signals]., Hirakawa Hidetada;Tomita Haruyoshi, Nihon saikingaku zasshi. Japanese journal of bacteriology, 68, 4
    DOI
  • Bacteriocin protein BacL1 of Enterococcus faecalis targets cell division loci and specifically recognizes L-Ala2-cross-bridged peptidoglycan., Kurushima Jun;Nakane Daisuke;Nishizaka Takayuki;Tomita Haruyoshi, 03 Nov. 2014, Journal of bacteriology, 197, 2
    DOI
  • Identification of a second two-component signal transduction system that controls fosfomycin tolerance and glycerol-3-phosphate uptake., Kurabayashi Kumiko;Hirakawa Yuko;Tanimoto Koichi;Tomita Haruyoshi;Hirakawa Hidetada, 15 Dec. 2014, Journal of bacteriology, 197, 5
    DOI
  • Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions., Kurabayashi Kumiko;Tanimoto Koichi;Fueki Shinobu;Tomita Haruyoshi;Hirakawa Hidetada, 27 Jul. 2015, Antimicrobial agents and chemotherapy, 59, 10
    DOI
  • Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis., Taniguchi Tomoyo;Miyauchi Eiji;Nakamura Shota;Hirai Makoto;Suzue Kazutomo;Imai Takashi;Nomura Takahiro;Handa Tadashi;Okada Hiroko;Shimokawa Chikako;Onishi Risa;Olia Alex;Hirata Jun;Tomita Haruyoshi;Ohno Hiroshi;Horii Toshihiro;Hisaeda Hajime, 27 Oct. 2015, Scientific reports, 5
    DOI
  • Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains., Kurushima Jun;Ike Yasuyoshi;Tomita Haruyoshi, 11 Aug. 2016, Journal of bacteriology, 198, 17
    DOI
  • Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli., Kurabayashi Kumiko;Agata Tomohiro;Asano Hirofumi;Tomita Haruyoshi;Hirakawa Hidetada, 17 Oct. 2016, Infection and immunity, 84, 11
    DOI
  • Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions., Kurabayashi Kumiko;Tanimoto Koichi;Tomita Haruyoshi;Hirakawa Hidetada, 16 Mar. 2017, Frontiers in microbiology, 8
    DOI
  • Postoperative Enterococcus faecalis endophthalmitis: virulence factors leading to poor visual outcome., Todokoro Daisuke;Suzuki Takashi;Kobayakawa Shinichiro;Tomita Haruyoshi;Ohashi Yuichi;Akiyama Hideo, 13 Jul. 2017, Japanese journal of ophthalmology, 61, 5
    DOI
  • New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species., Nomura Takahiro;Hashimoto Yusuke;Kurushima Jun;Hirakawa Hidetada;Tanimoto Koichi;Zheng Bo;Ruan Genjie;Xue Feng;Liu Jian;Hisatsune Junzo;Sugai Motoyuki;Tomita Haruyoshi, 05 Jan. 2018, Journal of microbiological methods, 145
    DOI
  • Genetic shifts in methicillin-resistant Staphylococcus aureus epidemic clones and toxin gene profiles in Japan: comparative analysis among pre-epidemic, epidemic and post-epidemic phases., Osaka Shunsuke;Okuzumi Katsuko;Koide Shota;Tamai Kiyoko;Sato Tomoaki;Tanimoto Koichi;Tomita Haruyoshi;Suzuki Masahiro;Nagano Yukiko;Shibayama Keigo;Arakawa Yoshichika;Nagano Noriyuki, 02 Feb. 2018, Journal of medical microbiology, 67, 3
    DOI
  • Membrane-active antimicrobial poly(amino-modified alkyl) β-cyclodextrins synthesized via click reactions., Yamamura Hatsuo;Nonaka Miho;Okuno Shingo;Mitsuhashi Ryogo;Kato Hisato;Katsu Takashi;Masuda Kazufumi;Tanimoto Koichi;Tomita Haruyoshi;Miyagawa Atsushi, 08 Feb. 2018, MedChemComm, 9, 3
    DOI
  • Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter., Hirakawa Hidetada;Kurabayashi Kumiko;Tanimoto Koichi;Tomita Haruyoshi, 21 Aug. 2018, Frontiers in microbiology, 9
    DOI
  • Genetic diversity and persistent colonization of Enterococcus faecalis on ocular surfaces., Todokoro Daisuke;Eguchi Hiroshi;Suzuki Takashi;Suzuki Motoo;Nakayama-Imaohji Haruyuki;Kuwahara Tomomi;Nomura Takahiro;Tomita Haruyoshi;Akiyama Hideo, 15 Oct. 2018, Japanese journal of ophthalmology, 62, 6
    DOI
  • Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan., Hashimoto Yusuke;Kurushima Jun;Nomura Takahiro;Tanimoto Koichi;Tamai Kiyoko;Yanagisawa Hideji;Shirabe Komei;Ike Yasuyoshi;Tomita Haruyoshi, 13 Dec. 2018, BMC microbiology, 18, 1
    DOI
  • Detection of mcr-1-mediated colistin resistance in E. coli isolate from imported chicken meat from Brazil., Chiba Naoko;Tanimoto Koichi;Hisatsune Junzo;Sugai Motoyuki;Shibayama Keigo;Watanabe Haruo;Tomita Haruyoshi, 14 Feb. 2019, Journal of global antimicrobial resistance, 16
    DOI
  • The Tol-Pal System of Uropathogenic Escherichia coli Is Responsible for Optimal Internalization Into and Aggregation Within Bladder Epithelial Cells, Colonization of the Urinary Tract of Mice, and Bacterial Motility., Hirakawa Hidetada;Suzue Kazutomo;Kurabayashi Kumiko;Tomita Haruyoshi, 07 Aug. 2019, Frontiers in microbiology, 10
    DOI
  • Roles of CytR, an anti-activator of cyclic-AMP receptor protein (CRP) on flagellar expression and virulence in uropathogenic Escherichia coli., Hirakawa Hidetada;Takita Ayako;Kato Mao;Mizumoto Hanano;Tomita Haruyoshi, 31 Oct. 2019, Biochemical and biophysical research communications, 521, 3
    DOI
  • Novel Multidrug-Resistant Enterococcal Mobile Linear Plasmid pELF1 Encoding vanA and vanM Gene Clusters From a Japanese Vancomycin-Resistant Enterococci Isolate., Hashimoto Yusuke;Taniguchi Makoto;Uesaka Kazuma;Nomura Takahiro;Hirakawa Hidetada;Tanimoto Koichi;Tamai Kiyoko;Ruan Genjie;Zheng Bo;Tomita Haruyoshi, 13 Nov. 2019, Frontiers in microbiology, 10
    DOI
  • First Report of the Local Spread of Vancomycin-Resistant Enterococci Ascribed to the Interspecies Transmission of a vanA Gene Cluster-Carrying Linear Plasmid., Hashimoto Yusuke;Kita Izumi;Suzuki Masato;Hirakawa Hidetada;Ohtaki Hirofumi;Tomita Haruyoshi, 08 Apr. 2020, mSphere, 5, 2
    DOI
  • In vitro activity of AST-120 that suppresses indole signaling in Escherichia coli, which attenuates drug tolerance and virulence., Hirakawa Hidetada;Uchida Motoyuki;Kurabayashi Kumiko;Nishijima Fuyuhiko;Takita Ayako;Tomita Haruyoshi, 29 Apr. 2020, PloS one, 15, 4
    DOI
  • Molecular pharmacology of ciclesonide against SARS-CoV-2., Kimura Hirokazu;Kurusu Hiromu;Sada Mitsuru;Kurai Daisuke;Murakami Koichi;Kamitani Wataru;Tomita Haruyoshi;Katayama Kazuhiko;Ryo Akihide, 13 Jun. 2020, The Journal of allergy and clinical immunology, 146, 2
    DOI
  • Effect of Sub-MICs of Macrolides on the Sensitivity of Pseudomonas aeruginosa to Nitrosative Stress: Effectiveness against P. aeruginosa with and without Multidrug Resistance., Shimizu Takeshi;Miyoshi-Akiyama Tohru;Ogura Kohei;Murata Shota;Ishige Shota;Kai Kiyohiro;Mitsutsuka Konosuke;Tomita Haruyoshi;Tanimoto Koichi;Matsumoto Akio, 21 Sep. 2020, Antimicrobial agents and chemotherapy, 64, 10
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  • Isolation of Serratia fonticola producing FONA, a minor extended-spectrum β-lactamase (ESBL), from imported chicken meat in Japan., Tanimoto Koichi;Nomura Takahiro;Hashimoto Yusuke;Hirakawa Hidetada;Watanabe Haruo;Tomita Haruyoshi, 01 Aug. 2020, Japanese journal of infectious diseases
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  • Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli., Hirakawa Hidetada;Suzue Kazutomo;Takita Ayako;Awazu Chikako;Kurushima Jun;Tomita Haruyoshi, 23 Sep. 2020, Scientific reports, 10, 1
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  • Progress Overview of Bacterial Two-Component Regulatory Systems as Potential Targets for Antimicrobial Chemotherapy., Hirakawa Hidetada;Kurushima Jun;Hashimoto Yusuke;Tomita Haruyoshi, 23 Sep. 2020, Antibiotics (Basel, Switzerland), 9, 10
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  • 腸管出血性大腸菌(EHEC)O157の腸管病原性におけるTol-Palシステムの役割, ;;;;, Aug. 2020, 70, 3, 298
  • Potency of carbapenems for the prevention of carbapenem-resistant mutants of Pseudomonas aeruginosa -: The high potency of a new carbapenem doripenem, Sakyo, Shihomi;Tomita, Haruyoshi;Tanimoto, Koichi;Fujimoto, Shuhei;Ike, Yasuyoshi, 2006, JOURNAL OF ANTIBIOTICS, 59, 4, 220, 228
  • Pheromone-responsive conjugative vancomycin resistance plasmids in Enterococcus faecalis isolates from humans and chicken feces, Lim, Suk-Kyung;Tanimoto, Koichi;Tomita, Haruyoshi;Ike, Yasuyoshi, 2006, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72, 10, 6544, 6553
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  • Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation, Tanimoto, Koichi;Tomita, Haruyoshi;Fujimoto, Shuhei;Okuzumi, Katsuko;Ike, Yasuyoshi, 2008, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 52, 10, 3795, 3800
    DOI
  • Genetic Analysis of the Enterococcus Vancomycin Resistance Conjugative Plasmid pHTβ: Identification of the Region Involved in Cell Aggregation and traB, a Key Regulator Gene for Plasmid Transfer and Cell Aggregation, Tomita, Haruyoshi;Ike, Yasuyoshi, 2008, JOURNAL OF BACTERIOLOGY, 190, 23, 7739, 7753
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  • Bacteriocin Protein BacL1 of Enterococcus faecalis Is a Peptidoglycan D-Isoglutamyl-L-lysine Endopeptidase, Kurushima, Jun;Hayashi, Ikue;Sugai, Motoyuki;Tomita, Haruyoshi, 2013, JOURNAL OF BIOLOGICAL CHEMISTRY, 288, 52, 36915, 36925
    DOI
  • Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance, Hirakawa, Hidetada;Tomita, Haruyoshi, 2013, FRONTIERS IN MICROBIOLOGY, 4
    DOI
  • Role of the CpxAR Two-Component Signal Transduction System in Control of Fosfomycin Resistance and Carbon Substrate Uptake, Kurabayashi, Kumiko;Hirakawa, Yuko;Tanimoto, Koichi;Tomita, Haruyoshi;Hirakawa, Hidetada, 2014, JOURNAL OF BACTERIOLOGY, 196, 2, 248, 256
    DOI
  • Membrane-active antimicrobial poly(amino-modified alkyl) β-cyclodextrins synthesized via click reactions, Yamamura, Hatsuo;Nonaka, Miho;Okuno, Shingo;Mitsuhashi, Ryogo;Kato, Hisato;Katsu, Takashi;Masuda, Kazufumi;Tanimoto, Koichi;Tomita, Haruyoshi;Miyagawa, Atsushi, 2018, MEDCHEMCOMM, 9, 3, 509, 518
    DOI
  • In vitro activity of AST-120 that suppresses indole signaling in Escherichia coli, which attenuates drug tolerance and virulence, Hirakawa, Hidetada;Uchida, Motoyuki;Kurabayashi, Kumiko;Nishijima, Fuyuhiko;Takita, Ayako;Tomita, Haruyoshi, 2020, PLOS ONE, 15, 4
    DOI
  • Progress Overview of Bacterial Two-Component Regulatory Systems as Potential Targets for Antimicrobial Chemotherapy, Hirakawa, Hidetada;Kurushima, Jun;Hashimoto, Yusuke;Tomita, Haruyoshi, 2020, ANTIBIOTICS-BASEL, 9, 10
    DOI
  • Isolation of Serratia fonticola Producing FONA, a Minor Extended-Spectrum β-Lactamase (ESBL), from Imported Chicken Meat in Japan, Tanimoto, Koichi;Nomura, Takahiro;Hashimoto, Yusuke;Hirakawa, Hidetada;Watanabe, Haruo;Tomita, Haruyoshi, 2021, JAPANESE JOURNAL OF INFECTIOUS DISEASES, 74, 1, 79, 81
    DOI
  • Inactivation of GalU Leads to a Cell Wall-Associated Polysaccharide Defect That Reduces the Susceptibility of Enterococcus faecalis to Bacteriolytic Agents, Kurushima, Jun;Tomita, Haruyoshi, 2021, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 87, 7
    DOI
  • Adsorption of Phenazines Produced by Pseudomonas aeruginosa Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity, Hirakawa, Hidetada;Takita, Ayako;Uchida, Motoyuki;Kaneko, Yuka;Kakishima, Yuto;Tanimoto, Koichi;Kamitani, Wataru;Tomita, Haruyoshi, 2021, ANTIBIOTICS-BASEL, 10, 4
    DOI
  • Roles of OmpX, an Outer Membrane Protein, on Virulence and Flagellar Expression in Uropathogenic Escherichia coli, Hirakawa, Hidetada;Suzue, Kazutomo;Takita, Ayako;Kamitani, Wataru;Tomita, Haruyoshi, 2021, INFECTION AND IMMUNITY, 89, 6
    DOI
  • Roles of OmpA in Type III Secretion System-Mediated Virulence of Enterohemorrhagic Escherichia coli, Hirakawa, Hidetada;Suzue, Kazutomo;Takita, Ayako;Tomita, Haruyoshi, 2021, PATHOGENS, 10, 11
    DOI
  • Editorial: Gram-Negative Pathogenesis, Hirakawa, Hidetada;Bordi, Christophe;Tomita, Haruyoshi, 2021, FRONTIERS IN MICROBIOLOGY, 12
    DOI
  • Roles of the Tol/Pal System in Bacterial Pathogenesis and Its Application to Antibacterial Therapy, Hirakawa, Hidetada;Suzue, Kazutomo;Tomita, Haruyoshi, 2022, VACCINES, 10, 3
    DOI
  • A Macroporous Magnesium Oxide-Templated Carbon Adsorbs Shiga Toxins and Type III Secretory Proteins in Enterohemorrhagic Escherichia coli, Which Attenuates Virulence, Hirakawa, Hidetada;Suzue, Kazutomo;Uchida, Motoyuki;Takita, Ayako;Kamitani, Wataru;Tomita, Haruyoshi, 2022, FRONTIERS IN MICROBIOLOGY, 13
    DOI
  • Advances of genetic engineering in streptococci and enterococci, Kurushima, Jun;Tomita, Haruyoshi, 2022, MICROBIOLOGY AND IMMUNOLOGY, 66, 9, 411, 417
    DOI
  • Patient-derived Enterococcus faecium with inflammatory genotypes promote colitis, Wang, Ziyu;Iida, Noriho;Seishima, Jun;Okafuji, Hirofumi;Yutani, Masahiro;Fujinaga, Yukako;Hashimoto, Yusuke;Tomita, Haruyoshi;Mizukoshi, Eishiro;Kaneko, Shuichi, 2022, JOURNAL OF GASTROENTEROLOGY, 57, 10, 770, 783
    DOI
  • Molecular Evolution of the Pseudomonas aeruginosa DNA Gyrase gyrA Gene, Sada, Mitsuru;Kimura, Hirokazu;Nagasawa, Norika;Akagawa, Mao;Okayama, Kaori;Shirai, Tatsuya;Sunagawa, Soyoka;Kimura, Ryusuke;Saraya, Takeshi;Ishii, Haruyuki;Kurai, Daisuke;Tsugawa, Takeshi;Nishina, Atsuyoshi;Tomita, Haruyoshi;Okodo, Mitsuaki;Hirai, Shinichiro;Ryo, Akihide;Ishioka, Taisei;Murakami, Koichi, 2022, MICROORGANISMS, 10, 8
    DOI
  • Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades, Hashimoto, Yusuke;Suzuki, Masato;Kobayashi, Sae;Hirahara, Yuki;Kurushima, Jun;Hirakawa, Hidetada;Nomura, Takahiro;Tanimoto, Koichi;Tomita, Haruyoshi, 2023, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 67, 4
    DOI
  • Molecular Evolutionary Analyses of the Pseudomonas-Derived Cephalosporinase Gene, Shirai, Tatsuya;Akagawa, Mao;Makino, Miho;Ishii, Manami;Arai, Ayaka;Nagasawa, Norika;Sada, Mitsuru;Kimura, Ryusuke;Okayama, Kaori;Ishioka, Taisei;Ishii, Haruyuki;Hirai, Shinichiro;Ryo, Akihide;Tomita, Haruyoshi;Kimura, Hirokazu, 2023, MICROORGANISMS, 11, 3
    DOI
  • Inactivation of ackA and pta Genes Reduces GlpT Expression and Susceptibility to Fosfomycin in Escherichia coli, Hirakawa, Hidetada;Takita, Ayako;Sato, Yumika;Hiramoto, Suguru;Hashimoto, Yusuke;Ohshima, Noriyasu;Minamishima, Yoji A.;Murakami, Masami;Tomita, Haruyoshi, 2023, MICROBIOLOGY SPECTRUM, 11, 3
    DOI
  • The PapB/FocB family protein TosR acts as a positive regulator of flagellar expression and is required for optimal virulence of uropathogenic Escherichia coli, Hirakawa, Hidetada;Shimokawa, Mizuki;Noguchi, Koshi;Tago, Minori;Matsuda, Hiroshi;Takita, Ayako;Suzue, Kazutomo;Tajima, Hirotaka;Kawagishi, Ikuro;Tomita, Haruyoshi, 2023, FRONTIERS IN MICROBIOLOGY, 14
    DOI
  • 腸管出血性大腸菌(EHEC)の病原性因子Tol/Palシステムの解析, ;;;;, Aug. 2020, 34回, 40
  • 腸管出血性大腸菌(EHEC)O157の腸管病原性におけるTol-Palシステムの役割, ;;;;, Aug. 2020, 70, 3, 298
  • 腸管出血性大腸菌の病原性におけるTol-Palシステムの役割, ;;;;, Jan. 2021, 69, 1, 89
  • VanA型バンコマイシン耐性遺伝子群保有線状プラスミドによるVRE院内感染事例の解析, ;;;;;;, Feb. 2021, 76, 1, 92
  • 腸内細菌における抗菌薬と薬剤耐性　腸球菌の耐性獲得とバンコマイシン耐性腸球菌VREの増加, 富田 治芳, Aug. 2021, 24回, 30
  • 【エキスパートに聞く 耐性菌と院内感染-産婦人科医に必要な基礎知識】耐性菌各論　診断法と制御・治療戦略　バンコマイシン耐性腸球菌(VRE), ;;, Aug. 2021, 75, 8, 734
  • 腸管出血性大腸菌(EHEC)の病原性因子Tol/Palシステムの解析, ;;;;, Jun. 2021, 34, 43
  • マクロ孔吸着炭を利用した腸管出血性大腸菌の志賀毒素と3型分泌蛋白質の吸着および、病原性抑制, ;, Jan. 2022, 70, 1, 165
  • 「腸内細菌における抗菌薬と薬剤耐性」　腸球菌の耐性獲得とバンコマイシン耐性腸球菌(VRE)の増加, 富田 治芳, Feb. 2022, 24, 1, 62
  • 選抜ワークショップ2:遺伝、分類、疫学　腸球菌の溶菌酵素Bac41は接合フェロモンによって発現制御され、細胞間のプラスミド維持に寄与する(Selected from Oral Session 2: Genetics, taxonomy and Epidemiology　Pheromone-responsive bacteriolysin Bac41 maintains plasmid propagation in Enterococcus faecalis), ;, Feb. 2022, 77, 1, 46
  • 腸球菌の線状プラスミドに関する分子疫学解析, ;;;;;;, Feb. 2022, 77, 1, 61
  • マクロ孔型の多孔質炭素は、腸管出血性大腸菌の病原性を抑制する, ;;;;, Feb. 2022, 77, 1, 90
  • VanD型バンコマイシン耐性Enterococcus faecalisの分子疫学的解析, ;;;;;;;, Feb. 2022, 77, 1, 112
  • 経口吸着炭AST-120による緑膿菌のピオシアニン吸着と病原性抑制, ;;;, Aug. 2021, 71, 3, 254
  • 細菌感染症の治療薬創出に挑む-細菌学者は何ができるのか?-　抗感染症薬としての吸着剤の可能性, ;, Feb. 2023, 78, 1, 33
  • 腸球菌の線状プラスミドがE.faeciumに適応し多剤耐性clade内に広がる(Enterococcal linear plasmids adapt to E.faecium and spread within multidrug-resistant clades), ;;;;;;, Feb. 2023, 78, 1, 66
  • 腸球菌のプラスミドをエンコードするBac41による溶菌におけるintact cell divisionの役割(Potential role of intact cell division on bacteriolysis by enterococcal plasmid-encoded Bac41), ;, Feb. 2023, 78, 1, 78
  • 腸球菌の線状プラスミドがEnterococcus faeciumに適応し多剤耐性clade内で拡散する(Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades), ;;;;, Mar. 2023, 97回・71回, O
  • バンコマイシン耐性腸球菌(vancomycin-resistant enterococci:VRE)の薬剤耐性機構について, 富田 治芳, Aug. 2021, 42, 8, 157
  • バンコマイシン耐性腸球菌(VRE)の家畜環境中での増加と輸入食肉を介したヒトへの伝播, 富田 治芳, Aug. 2021, 42, 8, 166
  • マクロ孔型吸着炭を利用した緑膿菌の病原性因子の吸着と弱毒化, ;;;;;, Feb. 2023, 57回, 30
  • 腸球菌線状プラスミドはEnterococcus faeciumに適応し多剤耐性Clade内で拡散する(Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades), ;;;;, Jul. 2023, 71, 4, 499
  • 多様な病原体研究が生み出す新たな生化学領域　薬剤耐性(AMR)遺伝子の拡散に寄与する選択的溶菌酵素, ;, Oct. 2023, 96回, [3S14a
  • 臨床医のための微生物学講座(Vol.8)　腸球菌, ;;, Apr. 2024, 289, 2, 156
  • 薬剤耐性菌研究の最前線　バンコマイシン耐性腸球菌(VRE), 富田 治芳, Jan. 2024, 72, 1, 44
  • ackAとpta遺伝子変異による大腸菌のホスホマイシン耐性化機構, ;;;, Jan. 2024, 72, 1, 107
  • 薬剤耐性菌研究の最前線　バンコマイシン耐性腸球菌(VRE), 富田 治芳, Jan. 2024, 98, 1, 38
  • 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染とマイクロコロニー形成における蛋白質TusDCBの役割, ;;;;;;;, Aug. 2023, 73, 3, 256
  • VREの脅威とその対策　VREの疫学と細菌学的な基礎知識, 富田 治芳, Jul. 2024, 39回, 187
  • Segatella copri JCM 13464Tの大麦β-グルカン代謝遺伝子群の同定, ;;;;;;;, Jun. 2024, 35, 2, 156
  • Fosfomycin　多剤耐性菌への新たな対抗手段としての展望, ;, Nov. 2024, 72, 6, 561
  • 院内アウトブレイクに関与したカルバペネム耐性緑膿菌(CRPA)24株の解析, ;;;;;;;, May 2024, 98回・72回, np200
  • 遺伝子水平伝播(HGT)現象の未踏領域　腸球菌のpELF1型伝達性線状プラスミドと薬剤耐性遺伝子, ;, Jun. 2024, 79, 2, 36
  • 選択ワークショップ5:抗菌性物質・薬剤耐性　AckAとPta,Fisの機能欠失による大腸菌のホスホマイシン耐性化機構, ;;;;;;;;, Jun. 2024, 79, 2, 71
  • 尿路病原性大腸菌(UPEC)の病原性とマイクロコロニー形成における硫黄転移酵素複合体TusDCBの役割, ;;;;;;;, Jun. 2024, 79, 2, 85
  • Inactivation of GalU Leads to a Cell Wall-Associated Polysaccharide Defect That Reduces the Susceptibility of Enterococcus faecalis to Bacteriolytic Agents., Kurushima Jun;Tomita Haruyoshi, Mar. 2021, Applied and environmental microbiology, 87, 7
    DOI
  • Roles of OmpX, an Outer Membrane Protein, on Virulence and Flagellar Expression in Uropathogenic Escherichia coli., Hirakawa Hidetada;Suzue Kazutomo;Takita Ayako;Kamitani Wataru;Tomita Haruyoshi, May 2021, Infection and immunity, 89, 6
    DOI
  • Adsorption of Phenazines Produced by Pseudomonas aeruginosa Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity., Hirakawa Hidetada;Takita Ayako;Uchida Motoyuki;Kaneko Yuka;Kakishima Yuto;Tanimoto Koichi;Kamitani Wataru;Tomita Haruyoshi, Apr. 2021, Antibiotics (Basel, Switzerland), 10, 4
    DOI
  • Roles of OmpA in Type III Secretion System-Mediated Virulence of Enterohemorrhagic Escherichia coli., Hirakawa Hidetada;Suzue Kazutomo;Takita Ayako;Tomita Haruyoshi, Nov. 2021, Pathogens (Basel, Switzerland), 10, 11
    DOI
  • Editorial: Gram-Negative Pathogenesis., Hirakawa Hidetada;Bordi Christophe;Tomita Haruyoshi, Dec. 2021, Frontiers in microbiology, 12
    DOI
  • Elucidation of host diversity of the VanD-carrying genomic islands in enterococci and anaerobes., Hashimoto Yusuke;Hisatsune Junzo;Suzuki Masato;Kurushima Jun;Nomura Takahiro;Hirakawa Hidetada;Kojima Naoko;Ono Yuichi;Hasegawa Yutaka;Tanimoto Koichi;Sugai Motoyuki;Tomita Haruyoshi, Jan. 2022, JAC-antimicrobial resistance, 4, 1
    DOI
  • Roles of the Tol/Pal System in Bacterial Pathogenesis and Its Application to Antibacterial Therapy., Hirakawa Hidetada;Suzue Kazutomo;Tomita Haruyoshi, Mar. 2022, Vaccines, 10, 3
    DOI
  • A Macroporous Magnesium Oxide-Templated Carbon Adsorbs Shiga Toxins and Type III Secretory Proteins in Enterohemorrhagic Escherichia coli, Which Attenuates Virulence., Hirakawa Hidetada;Suzue Kazutomo;Uchida Motoyuki;Takita Ayako;Kamitani Wataru;Tomita Haruyoshi, May 2022, Frontiers in microbiology, 13
    DOI
  • Advances of genetic engineering in streptococci and enterococci., Kurushima Jun;Tomita Haruyoshi, Jul. 2022, Microbiology and immunology, 66, 9
    DOI
  • Patient-derived Enterococcus faecium with inflammatory genotypes promote colitis., Wang Ziyu;Iida Noriho;Seishima Jun;Okafuji Hirofumi;Yutani Masahiro;Fujinaga Yukako;Hashimoto Yusuke;Tomita Haruyoshi;Mizukoshi Eishiro;Kaneko Shuichi, Jul. 2022, Journal of gastroenterology, 57, 10
    DOI
  • Molecular Evolution of the Pseudomonas aeruginosa DNA Gyrase gyrA Gene., Sada Mitsuru;Kimura Hirokazu;Nagasawa Norika;Akagawa Mao;Okayama Kaori;Shirai Tatsuya;Sunagawa Soyoka;Kimura Ryusuke;Saraya Takeshi;Ishii Haruyuki;Kurai Daisuke;Tsugawa Takeshi;Nishina Atsuyoshi;Tomita Haruyoshi;Okodo Mitsuaki;Hirai Shinichiro;Ryo Akihide;Ishioka Taisei;Murakami Koichi, Aug. 2022, Microorganisms, 10, 8
    DOI
  • Adsorption of extracellular proteases and pyocyanin produced by Pseudomonas aeruginosa using a macroporous magnesium oxide-templated carbon decreases cytotoxicity., Hirakawa Hidetada;Kimura Ayuko;Takita Ayako;Chihara Sayaka;Tanimoto Koichi;Tomita Haruyoshi, Aug. 2022, Current research in microbial sciences, 3
    DOI
  • Genomic Epidemiological Analysis of Antimicrobial-Resistant Bacteria with Nanopore Sequencing., Suzuki Masato;Hashimoto Yusuke;Hirabayashi Aki;Yahara Koji;Yoshida Mitsunori;Fukano Hanako;Hoshino Yoshihiko;Shibayama Keigo;Tomita Haruyoshi, Methods in molecular biology (Clifton, N.J.), 2632
    DOI
  • Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades., Hashimoto Yusuke;Suzuki Masato;Kobayashi Sae;Hirahara Yuki;Kurushima Jun;Hirakawa Hidetada;Nomura Takahiro;Tanimoto Koichi;Tomita Haruyoshi, Mar. 2023, Antimicrobial agents and chemotherapy, 67, 4
    DOI
  • Molecular Evolutionary Analyses of the Pseudomonas-Derived Cephalosporinase Gene., Shirai Tatsuya;Akagawa Mao;Makino Miho;Ishii Manami;Arai Ayaka;Nagasawa Norika;Sada Mitsuru;Kimura Ryusuke;Okayama Kaori;Ishioka Taisei;Ishii Haruyuki;Hirai Shinichiro;Ryo Akihide;Tomita Haruyoshi;Kimura Hirokazu, Mar. 2023, Microorganisms, 11, 3
    DOI
  • Inactivation of ackA and pta Genes Reduces GlpT Expression and Susceptibility to Fosfomycin in Escherichia coli., Hirakawa Hidetada;Takita Ayako;Sato Yumika;Hiramoto Suguru;Hashimoto Yusuke;Ohshima Noriyasu;Minamishima Yoji A;Murakami Masami;Tomita Haruyoshi, May 2023, Microbiology spectrum, 11, 3
    DOI
  • The PapB/FocB family protein TosR acts as a positive regulator of flagellar expression and is required for optimal virulence of uropathogenic Escherichia coli., Hirakawa Hidetada;Shimokawa Mizuki;Noguchi Koshi;Tago Minori;Matsuda Hiroshi;Takita Ayako;Suzue Kazutomo;Tajima Hirotaka;Kawagishi Ikuro;Tomita Haruyoshi, Jul. 2023, Frontiers in microbiology, 14
    DOI
  • Molecular epidemiological analyses of Clostridioides difficile isolates in a university hospital in Japan., Ito Yukitaka;Tanimoto Koichi;Chiba Naoko;Otsuka Masanobu;Ota Masato;Yoshida Mieko;Hashimoto Yusuke;Nomura Takahiro;Tomita Haruyoshi, Sep. 2023, Heliyon, 9, 10
    DOI
  • High Incidence of Multiple-Drug-Resistant Pheromone-Responsive Plasmids and Transmissions of VanA-Type Vancomycin-Resistant Enterococcus faecalis between Livestock and Humans in Taiwan., Tomita Haruyoshi;Lu Jang-Jih;Ike Yasuyoshi, Nov. 2023, Antibiotics (Basel, Switzerland), 12, 12
    DOI
  • Vancomycin-resistant Enterococcus(VRE), ;;;;;, Jan. 2016, 60, 1, 68, 82
    DOI
  • 経口吸着炭AST-120による緑膿菌のピオシアニン吸着と病原性抑制, ;;;, Aug. 2021, 71, 3, 254
  • 選抜ワークショップ2:遺伝、分類、疫学　腸球菌の溶菌酵素Bac41は接合フェロモンによって発現制御され、細胞間のプラスミド維持に寄与する(Selected from Oral Session 2: Genetics, taxonomy and Epidemiology　Pheromone-responsive bacteriolysin Bac41 maintains plasmid propagation in Enterococcus faecalis), ;, Feb. 2022, 77, 1, 46
  • 腸球菌の線状プラスミドに関する分子疫学解析, ;;;;;;, Feb. 2022, 77, 1, 61
  • マクロ孔型の多孔質炭素は、腸管出血性大腸菌の病原性を抑制する, ;;;;, Feb. 2022, 77, 1, 90
  • VanD型バンコマイシン耐性Enterococcus faecalisの分子疫学的解析, ;;;;;;;, Feb. 2022, 77, 1, 112
  • バンコマイシン耐性腸球菌(vancomycin-resistant enterococci:VRE)の薬剤耐性機構について, 富田 治芳, Aug. 2021, 42, 8, 157
  • バンコマイシン耐性腸球菌(VRE)の家畜環境中での増加と輸入食肉を介したヒトへの伝播, 富田 治芳, Aug. 2021, 42, 8, 166
  • 腸球菌線状プラスミドはEnterococcus faeciumに適応し多剤耐性Clade内で拡散する(Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades), ;;;;, Jul. 2023, 71, 4, 499
  • 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染とマイクロコロニー形成における蛋白質TusDCBの役割, ;;;;;;;, Aug. 2023, 73, 3, 256
  • マクロ孔型吸着炭を利用した緑膿菌の病原性因子の吸着と弱毒化, ;;;;;, Feb. 2023, 57回, 30
  • 多様な病原体研究が生み出す新たな生化学領域　薬剤耐性(AMR)遺伝子の拡散に寄与する選択的溶菌酵素, ;, Oct. 2023, 96回, [3S14a
  • 薬剤耐性菌研究の最前線　バンコマイシン耐性腸球菌(VRE), 富田 治芳, Jan. 2024, 98, 1, 38
  • 薬剤耐性菌研究の最前線　バンコマイシン耐性腸球菌(VRE), 富田 治芳, Jan. 2024, 72, 1, 44
  • ackAとpta遺伝子変異による大腸菌のホスホマイシン耐性化機構, ;;;, Jan. 2024, 72, 1, 107
  • 臨床医のための微生物学講座(Vol.8)　腸球菌, ;;, Apr. 2024, 289, 2, 156
  • 院内アウトブレイクに関与したカルバペネム耐性緑膿菌(CRPA)24株の解析, ;;;;;;;, May 2024, 98回・72回, np200
  • Segatella copri JCM 13464Tの大麦β-グルカン代謝遺伝子群の同定, ;;;;;;;, Jun. 2024, 35, 2, 156
  • 遺伝子水平伝播(HGT)現象の未踏領域　腸球菌のpELF1型伝達性線状プラスミドと薬剤耐性遺伝子, ;, Jun. 2024, 79, 2, 36
  • 選択ワークショップ5:抗菌性物質・薬剤耐性　AckAとPta,Fisの機能欠失による大腸菌のホスホマイシン耐性化機構, ;;;;;;;;, Jun. 2024, 79, 2, 71
  • 尿路病原性大腸菌(UPEC)の病原性とマイクロコロニー形成における硫黄転移酵素複合体TusDCBの役割, ;;;;;;;, Jun. 2024, 79, 2, 85
  • VREの脅威とその対策　VREの疫学と細菌学的な基礎知識, 富田 治芳, Jul. 2024, 39回, 187
  • Fosfomycin　多剤耐性菌への新たな対抗手段としての展望, ;, Nov. 2024, 72, 6, 561
  • 尿路病原性大腸菌(UPEC)による尿路感染症(UTI)難治化因子TusDCBの機能解析, ;;;;, Jan. 2025, 73, 1, 57

MISC

  • Cloning and genetic analyses of the bacteriocin 41 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pYI14: a novel bacteriocin complemented by two extracellular components (Lysin and activator), Haruyoshi Tomita,Elizabeth Kamei,Yasuyoshi Ike, Mar. 2008, JOURNAL OF BACTERIOLOGY, 190, 6, 2075, 2085
    DOI
  • Cloning and genetic analyses of the bacteriocin 41 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pYI14: a novel bacteriocin complemented by two extracellular components (Lysin and activator), Haruyoshi Tomita,Elizabeth Kamei,Yasuyoshi Ike, Mar. 2008, JOURNAL OF BACTERIOLOGY, 190, 6, 2075, 2085
    DOI
  • Genetic Analysis of the Enterococcus Vancomycin Resistance Conjugative Plasmid pHT beta: Identification of the Region Involved in Cell Aggregation and traB, a Key Regulator Gene for Plasmid Transfer and Cell Aggregation, Haruyoshi Tomita,Yasuyoshi Ike, Dec. 2008, JOURNAL OF BACTERIOLOGY, 190, 23, 7739, 7753
    DOI
  • Genetic Analysis of the Enterococcus Vancomycin Resistance Conjugative Plasmid pHT beta: Identification of the Region Involved in Cell Aggregation and traB, a Key Regulator Gene for Plasmid Transfer and Cell Aggregation, Haruyoshi Tomita,Yasuyoshi Ike, Dec. 2008, JOURNAL OF BACTERIOLOGY, 190, 23, 7739, 7753
    DOI
  • Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation, Koichi Tanimoto,Haruyoshi Tomita,Shuhei Fujimoto,Katsuko Okuzumi,Yasuyoshi Ike, Oct. 2008, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 52, 10, 3795, 3800
    DOI
  • Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation, Koichi Tanimoto,Haruyoshi Tomita,Shuhei Fujimoto,Katsuko Okuzumi,Yasuyoshi Ike, Oct. 2008, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 52, 10, 3795, 3800
    DOI
  • Identification of a Second Two-Component Signal Transduction System That Controls Fosfomycin Tolerance and Glycerol-3-Phosphate Uptake, Kumiko Kurabayashi,Yuko Hirakawa,Koichi Tanimoto,Haruyoshi Tomita,Hidetada Hirakawa, Mar. 2015, JOURNAL OF BACTERIOLOGY, 197, 5, 861, 871
    DOI
  • Identification of a Second Two-Component Signal Transduction System That Controls Fosfomycin Tolerance and Glycerol-3-Phosphate Uptake, Kumiko Kurabayashi,Yuko Hirakawa,Koichi Tanimoto,Haruyoshi Tomita,Hidetada Hirakawa, Mar. 2015, JOURNAL OF BACTERIOLOGY, 197, 5, 861, 871
    DOI
  • Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis, Tomoyo Taniguchi,Eiji Miyauchi,Shota Nakamura,Makoto Hirai,Kazutomo Suzue,Takashi Imai,Takahiro Nomura,Tadashi Handa,Hiroko Okada,Chikako Shimokawa,Risa Onishi,Alex Olia,Jun Hirata,Haruyoshi Tomita,Hiroshi Ohno,Toshihiro Horii,Hajime Hisaeda, Oct. 2015, SCIENTIFIC REPORTS, 5, 15669
    DOI
  • Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis, Tomoyo Taniguchi,Eiji Miyauchi,Shota Nakamura,Makoto Hirai,Kazutomo Suzue,Takashi Imai,Takahiro Nomura,Tadashi Handa,Hiroko Okada,Chikako Shimokawa,Risa Onishi,Alex Olia,Jun Hirata,Haruyoshi Tomita,Hiroshi Ohno,Toshihiro Horii,Hajime Hisaeda, Oct. 2015, SCIENTIFIC REPORTS, 5, 15669
    DOI
  • Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions, Kumiko Kurabayashi,Koichi Tanimoto,Shinobu Fueki,Haruyoshi Tomita,Hidetada Hirakawa, Oct. 2015, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59, 10, 6352, 6360
    DOI
  • Assessment of Antibiotic Resistance in Probiotic Strain Lactobacillus brevis KB290, Masanori Fukao,Haruyoshi Tomita,Takafumi Yakabe,Takahiro Nomura,Yasuyoshi Ike,Nobuhiro Yajima, Sep. 2009, JOURNAL OF FOOD PROTECTION, 72, 9, 1923, 1929
  • Assessment of Antibiotic Resistance in Probiotic Strain Lactobacillus brevis KB290, Masanori Fukao,Haruyoshi Tomita,Takafumi Yakabe,Takahiro Nomura,Yasuyoshi Ike,Nobuhiro Yajima, Sep. 2009, JOURNAL OF FOOD PROTECTION, 72, 9, 1923, 1929
  • Cloning and genetic and sequence analyses of the bacteriocin 21 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pPD1, H Tomita,S Fujimoto,K Tanimoto,Y Ike, Dec. 1997, JOURNAL OF BACTERIOLOGY, 179, 24, 7843, 7855
  • Genetic analysis of transfer-related regions of the vancomycin resistance Enterococcus conjugative plasmid pHT beta: Identification of oriT and a putative relaxase gene, H Tomita,Y Ike, Nov. 2005, JOURNAL OF BACTERIOLOGY, 187, 22, 7727, 7737
    DOI
  • Identification of VanN-Type Vancomycin Resistance in an Enterococcus faecium Isolate from Chicken Meat in Japan, Takahiro Nomura,Koichi Tanimoto,Keigo Shibayama,Yoshichika Arakawa,Shuhei Fujimoto,Yasuyoshi Ike,Haruyoshi Tomita, Dec. 2012, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56, 12, 6389, 6392
    DOI
  • Identification of VanN-Type Vancomycin Resistance in an Enterococcus faecium Isolate from Chicken Meat in Japan, Takahiro Nomura,Koichi Tanimoto,Keigo Shibayama,Yoshichika Arakawa,Shuhei Fujimoto,Yasuyoshi Ike,Haruyoshi Tomita, Dec. 2012, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56, 12, 6389, 6392
    DOI
  • Possible connection between a widely disseminated conjugative gentamicin resistance (pMG1-like) plasmid and the emergence of vancomycin resistance in Enterococcus faecium, H Tomita,C Pierson,SK Lim,DB Clewell,Y Ike, Sep. 2002, JOURNAL OF CLINICAL MICROBIOLOGY, 40, 9, 3326, 3333
    DOI
  • Possible connection between a widely disseminated conjugative gentamicin resistance (pMG1-like) plasmid and the emergence of vancomycin resistance in Enterococcus faecium, H Tomita,C Pierson,SK Lim,DB Clewell,Y Ike, Sep. 2002, JOURNAL OF CLINICAL MICROBIOLOGY, 40, 9, 3326, 3333
    DOI
  • Highly conjugative pMG1-like plasmids carrying Tn1546-like transposons that encode vancomycin resistance in Enterococcus faecium, H Tomita,K Tanimoto,S Hayakawa,K Morinaga,K Ezaki,H Oshima,Y Ike, Dec. 2003, JOURNAL OF BACTERIOLOGY, 185, 23, 7024, 7028
    DOI
  • Highly conjugative pMG1-like plasmids carrying Tn1546-like transposons that encode vancomycin resistance in Enterococcus faecium, H Tomita,K Tanimoto,S Hayakawa,K Morinaga,K Ezaki,H Oshima,Y Ike, Dec. 2003, JOURNAL OF BACTERIOLOGY, 185, 23, 7024, 7028
    DOI
  • Tissue-specific adherent Enterococcus faecalis strains that show highly efficient adhesion to human bladder carcinoma T24 cells also adhere to extracellular matrix proteins, H Tomita,Y Ike, Oct. 2004, INFECTION AND IMMUNITY, 72, 10, 5877, 5885
    DOI
  • Tissue-specific adherent Enterococcus faecalis strains that show highly efficient adhesion to human bladder carcinoma T24 cells also adhere to extracellular matrix proteins, H Tomita,Y Ike, Oct. 2004, INFECTION AND IMMUNITY, 72, 10, 5877, 5885
    DOI
  • Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli, Kumiko Kurabayashi,Tomohiro Agata,Hirofumi Asano,Haruyoshi Tomita,Hidetada Hirakawa, Nov. 2016, INFECTION AND IMMUNITY, 84, 11, 3220, 3231
    DOI
  • Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli, Kumiko Kurabayashi,Tomohiro Agata,Hirofumi Asano,Haruyoshi Tomita,Hidetada Hirakawa, Nov. 2016, INFECTION AND IMMUNITY, 84, 11, 3220, 3231
    DOI
  • Rule of Hydrophobicity/Hydrophilicity Balance in Membrane-Disrupting Antimicrobial Activity of Polyalkylamino Cyclodextrins Synthesized via Click Chemistry, Hatsuo Yamamura,Atsushi Miyagawa,Hiroki Sugiyama,Kensuke Murata,Takahiro Mabuti,Ryogo Mitsuhashi,Tatsuya Hagiwara,Miho Nonaka,Koichi Tanimoto,Haruyoshi Tomita, Mar. 2016, CHEMISTRYSELECT, 1, 3, 469, 472
    DOI
  • Rule of Hydrophobicity/Hydrophilicity Balance in Membrane-Disrupting Antimicrobial Activity of Polyalkylamino Cyclodextrins Synthesized via Click Chemistry, Hatsuo Yamamura,Atsushi Miyagawa,Hiroki Sugiyama,Kensuke Murata,Takahiro Mabuti,Ryogo Mitsuhashi,Tatsuya Hagiwara,Miho Nonaka,Koichi Tanimoto,Haruyoshi Tomita, Mar. 2016, CHEMISTRYSELECT, 1, 3, 469, 472
    DOI
  • A pAD1-encoded small RNA molecule, mD, negatively regulates Enterococcus faecalis pheromone response by enhancing transcription termination, H Tomita,DB Clewell, Feb. 2000, JOURNAL OF BACTERIOLOGY, 182, 4, 1062, 1073
    DOI
  • A pAD1-encoded small RNA molecule, mD, negatively regulates Enterococcus faecalis pheromone response by enhancing transcription termination, H Tomita,DB Clewell, Feb. 2000, JOURNAL OF BACTERIOLOGY, 182, 4, 1062, 1073
    DOI
  • Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010, Y. Li,H. Tomita,Y. Lv,J. Liu,F. Xue,B. Zheng,Y. Ike, Jan. 2011, JOURNAL OF APPLIED MICROBIOLOGY, 110, 1, 254, 265
    DOI
  • Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010, Y. Li,H. Tomita,Y. Lv,J. Liu,F. Xue,B. Zheng,Y. Ike, Jan. 2011, JOURNAL OF APPLIED MICROBIOLOGY, 110, 1, 254, 265
    DOI
  • Genetic Organization and Mode of Action of a Novel Bacteriocin, Bacteriocin 51: Determinant of VanA-Type Vancomycin-Resistant Enterococcus faecium, Hitoshi Yamashita,Haruyoshi Tomita,Takako Inoue,Yasuyoshi Ike, Sep. 2011, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55, 9, 4352, 4360
    DOI
  • Genetic Organization and Mode of Action of a Novel Bacteriocin, Bacteriocin 51: Determinant of VanA-Type Vancomycin-Resistant Enterococcus faecium, Hitoshi Yamashita,Haruyoshi Tomita,Takako Inoue,Yasuyoshi Ike, Sep. 2011, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55, 9, 4352, 4360
    DOI
  • Nosocomial infection caused by vancomycin-susceptible multidrug-resistant Enterococcus faecalis over a long period in a university hospital in Japan, Michiaki Kudo,Takahiro Nomura,Sachie Yomoda,Koichi Tanimoto,Haruyoshi Tomita, Nov. 2014, MICROBIOLOGY AND IMMUNOLOGY, 58, 11, 607, 614
    DOI
  • Nosocomial infection caused by vancomycin-susceptible multidrug-resistant Enterococcus faecalis over a long period in a university hospital in Japan, Michiaki Kudo,Takahiro Nomura,Sachie Yomoda,Koichi Tanimoto,Haruyoshi Tomita, Nov. 2014, MICROBIOLOGY AND IMMUNOLOGY, 58, 11, 607, 614
    DOI
  • Role of the CpxAR Two-Component Signal Transduction System in Control of Fosfomycin Resistance and Carbon Substrate Uptake, Kumiko Kurabayashi,Yuko Hirakawa,Koichi Tanimoto,Haruyoshi Tomita,Hidetada Hirakawa, Jan. 2014, JOURNAL OF BACTERIOLOGY, 196, 2, 248, 256
    DOI
  • Role of the CpxAR Two-Component Signal Transduction System in Control of Fosfomycin Resistance and Carbon Substrate Uptake, Kumiko Kurabayashi,Yuko Hirakawa,Koichi Tanimoto,Haruyoshi Tomita,Hidetada Hirakawa, Jan. 2014, JOURNAL OF BACTERIOLOGY, 196, 2, 248, 256
    DOI
  • Postoperative Enterococcus faecalis endophthalmitis: virulence factors leading to poor visual outcome, Daisuke Todokoro,Takashi Suzuki,Shinichiro Kobayakawa,Haruyoshi Tomita,Yuichi Ohashi,Hideo Akiyama, Sep. 2017, JAPANESE JOURNAL OF OPHTHALMOLOGY, 61, 5, 408, 414
    DOI
  • Postoperative Enterococcus faecalis endophthalmitis: virulence factors leading to poor visual outcome, Daisuke Todokoro,Takashi Suzuki,Shinichiro Kobayakawa,Haruyoshi Tomita,Yuichi Ohashi,Hideo Akiyama, Sep. 2017, JAPANESE JOURNAL OF OPHTHALMOLOGY, 61, 5, 408, 414
    DOI
  • Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions, Kumiko Kurabayashi,Koichi Tanimoto,Haruyoshi Tomita,Hidetada Hirakawa, Mar. 2017, FRONTIERS IN MICROBIOLOGY, 8, 426
    DOI
  • New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species, Takahiro Nomura,Yusuke Hashimoto,Jun Kurushima,Hidetada Hirakawa,Koichi Tanimoto,Bo Zheng,Genjie Ruan,Feng Xue,Jian Liu,Junzo Hisatsune,Motoyuki Sugai,Haruyoshi Tomita, Feb. 2018, Journal of Microbiological Methods, 145, 69, 72
    DOI
  • Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains, Jun Kurushima,Yasuyoshi Ike,Haruyoshi Tomita,P. J. Christie, Jun. 2016, Journal of Bacteriology, 198, 17, 2379, 2390
    DOI
  • Bacteriocin Protein BacL1of Enterococcus faecalis Targets Cell Division Loci and Specifically Recognizes l-Ala2-Cross-Bridged Peptidoglycan, Jun Kurushima,Daisuke Nakane,Takayuki Nishizaka,Haruyoshi Tomita,P. J. Christie, 03 Nov. 2014, Journal of Bacteriology, 197, 2, 286, 295
    DOI
  • Bacteriocin Protein BacL1ofEnterococcus faecalisIs a Peptidoglycan d-Isoglutamyl-l-lysine Endopeptidase, Jun Kurushima,Ikue Hayashi,Motoyuki Sugai,Haruyoshi Tomita, Nov. 2013, Journal of Biological Chemistry, 288, 52, 36915, 36925
    DOI
  • New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species, Takahiro Nomura,Yusuke Hashimoto,Jun Kurushima,Hidetada Hirakawa,Koichi Tanimoto,Bo Zheng,Genjie Ruan,Feng Xue,Jian Liu,Junzo Hisatsune,Motoyuki Sugai,Haruyoshi Tomita, Feb. 2018, Journal of Microbiological Methods, 145, 69, 72
    DOI
  • Partial Diversity Generates Effector Immunity Specificity of the Bac41-Like Bacteriocins of Enterococcus faecalis Clinical Strains, Jun Kurushima,Yasuyoshi Ike,Haruyoshi Tomita,P. J. Christie, Jun. 2016, Journal of Bacteriology, 198, 17, 2379, 2390
    DOI
  • Bacteriocin Protein BacL1ofEnterococcus faecalisIs a Peptidoglycan d-Isoglutamyl-l-lysine Endopeptidase, Jun Kurushima,Ikue Hayashi,Motoyuki Sugai,Haruyoshi Tomita, Nov. 2013, Journal of Biological Chemistry, 288, 52, 36915, 36925
    DOI
  • Bacteriocin protein BacL1 of Enterococcus faecalis targets cell division loci and specifically recognizes L-Ala2-cross-bridged peptidoglycan., Kurushima J,Nakane D,Nishizaka T,Tomita H, Jan. 2015, 197, 2, 286, 295
    DOI
  • Cloning and Genetic Organization of the Bacteriocin 31 Determinant Encoded on the Enterococcus faecalis Pheromone-Responsive Conjugative Plasmid pYI17., TOMITA HARUYOSHI,FUJIMOTO SHUHEI,TANIMOTO KOICHI,IKE YASUYOSHI, 1996, Journal of Bacteriology, 178, 12, 3585, 3593
  • Cloning and Genetic and Sequence Analyses of the Bacteriocin 21 Determinant Encoded on the Enterococcus faecalis Pheromone-Responsive Conjugative Plasmid pPD1., TOMITA HARUYOSHI,FUJIMOTO SHUHEI,TANIMOTO KOICHI,IKE YASUYOSHI, 1997, Journal of Bacteriology, 179, 24, 7843, 7855
  • Isolation of VanB-type Enterococcus faecdalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, encoding VanB-type vancomycin resistance and an Bac41-type bacteriocin, and・・・, Zheng B,Tomita H,Inoue T,Ike Y, 2009, Antimicrob Agents Chemother, 53, 2, 735, 747
    DOI
  • Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance, Hirakawa\, Hidetada,Tomita\, Haruyoshi, 2013, FRONTIERS IN MICROBIOLOGY, 4, 114
    DOI
  • Genetic shifts in methicillin-resistant Staphylococcus aureus epidemic clones and toxin gene profiles in Japan: comparative analysis among pre-epidemic, epidemic and post-epidemic phases, Osaka\, Shunsuke,Okuzumi\, Katsuko,Koide\, Shota,Tamai\, Kiyoko,Sato\, Tomoaki,Tanimoto\, Koichi,Tomita\, Haruyoshi,Suzuki\, Masahiro,Nagano\, Yukiko,Shibayama\, Keigo,Arakawa\, Yoshichika,Nagano\, Noriyuki, 2018, JOURNAL OF MEDICAL MICROBIOLOGY, 67, 3, 392, 399
    DOI
  • Identification of Novel Genes Responsible for Overexpression of ampC in Pseudomonas aeruginosa PAO1, Tsutsumi\, Yuko,Tomita\, Haruyoshi,Tanimoto\, Koichi, 2013, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 57, 12, 5987, 5993
    DOI
  • Genetic analysis of transfer-related regions of the vancomycin resistance Enterococcus conjugative plasmid pHTbeta: identification of oriT and a putative relaxase gene, TOMITA HARUYOSHI,IKE YASUYOSHI, 2005, 187, 22, 7727, 7737
    DOI
  • Cloning and Genetic Organization of the Bacteriocin 31 Determinant Encoded on the Enterococcus faecalis Pheromone-Responsive Conjugative Plasmid pYI17., TOMITA HARUYOSHI,FUJIMOTO SHUHEI,TANIMOTO KOICHI,IKE YASUYOSHI, 1996, 178, 12, 3585, 3593
  • Isolation of VanB-type Enterococcus faecdalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, encoding VanB-type vancomycin resistance and an Bac41-type bacteriocin, and・・・, Zheng B,Tomita H,Inoue T,Ike Y, 2009, 53, 2, 735, 747
    DOI
  • 腸球菌の高頻度接合伝達性プラスミド, 富田治芳, 2009, 64, 2-4, 343, 355
    DOI
  • Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance, Hirakawa\, Hidetada,Tomita\, Haruyoshi, 2013, 4, 114
    DOI
  • Genetic shifts in methicillin-resistant Staphylococcus aureus epidemic clones and toxin gene profiles in Japan: comparative analysis among pre-epidemic, epidemic and post-epidemic phases, Osaka\, Shunsuke,Okuzumi\, Katsuko,Koide\, Shota,Tamai\, Kiyoko,Sato\, Tomoaki,Tanimoto\, Koichi,Tomita\, Haruyoshi,Suzuki\, Masahiro,Nagano\, Yukiko,Shibayama\, Keigo,Arakawa\, Yoshichika,Nagano\, Noriyuki, 2018, 67, 3, 392, 399
    DOI
  • Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions, Kurabayashi\, Kumiko,Tanimoto\, Koichi,Tomita\, Haruyoshi,Hirakawa\, Hidetada, 2017, 8, 426
    DOI
  • Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions, Kurabayashi\, Kumiko,Tanimoto\, Koichi,Fueki\, Shinobu,Tomita\, Haruyoshi,Hirakawa\, Hidetada, 2015, 59, 10, 6352, 6360
    DOI
  • Identification of Novel Genes Responsible for Overexpression of ampC in Pseudomonas aeruginosa PAO1, Tsutsumi\, Yuko,Tomita\, Haruyoshi,Tanimoto\, Koichi, 2013, 57, 12, 5987, 5993
    DOI

Books etc

  • 腸球菌のフェロモン様因子, 2002
  • 腸球菌-感染症、病原因子、接合伝達性プラスミドー, 1997

Presentations

  • Pheromone-Responsive Bacteriocin Plasmids pYI12 and pYI14, and Cloning of the Determinants for Bacteriocin 41, a New Type Bacteriocin Encoded on pYI14, 1st International ASM Conference on Enterococci, 2000
  • 腸球菌フェロモン反応性高頻度伝達性プラスミドpYI12及びpYI14のバクテリオシン遺伝子の解析, 第74回日本細菌学会総会, 2001
  • Enterococcus faecalisのフェロモン反応性接合伝達性プラスミドpYI14にコードされるバクテリオシン決定因子の解析, 第85回日本細菌学会関東支部総会, 2002
  • 日本で初めての院内感染症例から分離されたバンコマイシン耐性腸球菌(VRE)の解析, 第78回日本細菌学会総会, 2005
  • グラム陽性菌におけるグリコペプチド耐性菌の現状と分子疫学, 第74回日本細菌学会, 2001
  • 本邦におけるVREの細菌学的特性, 第15回日本臨床微生物学会総会, 2004
  • 臨床分離バンコマイシン耐性腸球菌(VRE)のバクテリオシンプラスミドの解析, 第76回日本細菌学会総会, 2003
  • バンコマイシン耐性腸球菌(VRE)のバクテリオシンの解析, 第77回日本細菌学会総会, 2004
  • Pheromone-Responsive Bacteriocin Plasmids pYI12 and pYI14, and Cloning of the Determinants for Bacteriocin 41, a New Type Bacteriocin Encoded on pYI14, 1st International ASM Conference on Enterococci, 2000

Awards

  • 2009

Research Projects

  • Genetic Analyses of Bacteriocin of Enterococcus faecalis, Grant-in-Aid for Scientific Research, 1992, Competitive research funding
  • study of highly conjugative plasmids in enterococci, Grant-in-Aid for Scientific Research, 1993, Competitive research funding
  • study of enterococcaal adhesin, Grant-in-Aid for Scientific Research, 1999, Competitive research funding
  • study of bacterial drug resistances, Grant-in-Aid for Scientific Research, 1994, Competitive research funding
  • study of the ultraviolet-rays resistance (UVr) of enterococci, Grant-in-Aid for Scientific Research, 2001, Competitive research funding
  • 1992, Competitive research funding
  • 1993, Competitive research funding
  • 1999, Competitive research funding
  • 1994, Competitive research funding
  • 2001, Competitive research funding

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