Researcher Profile and Settings

Researcher

• Name

  HIRAKAWA Hidetada

Profile and Settings

• Name

  Hirakawa, Hidetada

Foreign language

• Use in presentation

  English

• Use in publication

  English

Affiliation

• Gunma University
• Gunma University

Degree

• Ph.D. Pharmaceutical Sciences
• Ph.D. Pharmaceutical Sciences

Research Experience

• 2006, 2007, Graduate school of pharmaceutical sciences, Chiba University Research associate
• 2007, 2008, Institute of Scientific and Industrial Research
• 2008, 2012, University of Washington (Seattle) Department of Microbiology Postdoctoral fellow
• 2006, 2007, Chiba University, Graduate School of Pharmaceutical Sciences
• 2007, 2008, Osaka University, The Institute of Scientific and Industrial Research
• 2008, 2012
• Apr. 2020, 9999
• Apr. 2017, Mar. 2020
• Apr. 2012, Mar. 2017

Research Activities

Research Areas

• Life sciences, Bacteriology

Research Interests

• Quorum SensingDrug resistancePathogenicitySignal transductionMolecular genetics

Published Papers

• The Response Regulator OmpR Negatively Controls the Expression of Genes Implicated in Tilimycin and Tilivalline Cytotoxin Production in Klebsiella oxytoca, Ramon G Varela-Najera, Miguel A De la Cruz, Jorge Soria-Bustos, Carmen Gonzalez-Horta, Ma Carmen E Delgado-Gardea, Jorge A Yanez-Santos, Maria L Cedillo, Hidetada Hirakawa. James G Fox, Blanca Sanchez-Ramirez, Miguel A Ares, Jan. 2025, Microorganisms, 13, 158, 158, Scientific journal
• Homology of Escherichia coli isolated from urine and vagina and their antimicrobial susceptibility in postmenopausal women with recurrent cystitis, Takanori Sekito, Takuya Sadahira, Hidetada Hirakawa, Ayano Ishii, Koichiro Wada, Motoo Araki, 2024, Journal of Infection and Chemotherapy, 30, 1081, 1084, Scientific journal
• TusDCB, a sulfur transferase complex involved in tRNA modification, contributes to UPEC pathogenicity, Sato Yumika, Takita Ayako, Suzue Kazutomo, Hashimoto Yusuke, Hiramoto Suguru, Murakami Masami, Tomita Haruyoshi, Hirakawa Hidetada, 2024, Scientific Reports, 14, 8978, 8978, Scientific journal

  DOI
• Adsorption of extracellular proteases and pyocyanin produced by Pseudomonas aeruginosa using a macroporous magnesium oxide-templated carbon decreases cytotoxicity, Hidetada Hirakawa, Ayuko Kimura, Ayako Takita, Sayaka Chihara, Koichi Tanimoto, Haruyoshi Tomita, Aug. 2022, Current Research in Microbial Sciences, 3, 100160, 100160, Scientific journal

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• AcrS/EnvR represses expression of the acrAB multidrug efflux genes in Escherichia coli, Hidetada Hirakawa; Asuka Takumi-Kobayashi; Ulrike Theisen; Takahiro Hirata; Kunihiko Nishino; Akihito Yamaguchi, Sep. 2008, JOURNAL OF BACTERIOLOGY, 190, 18, 6276, 6279, Scientific journal

  DOI
• BadR and BadM Proteins Transcriptionally Regulate Two Operons Needed for Anaerobic Benzoate Degradation by Rhodopseudomonas palustris, Hidetada Hirakawa; Yuko Hirakawa; E. Peter Greenberg; Caroline S. Harwood, Jul. 2015, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81, 13, 4253, 4262, Scientific journal

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• Secreted indole serves as a signal for expression of type III secretion system translocators in enterohaemorrhagic Escherichia coli O157: H7, Hidetada Hirakawa; Toshio Kodama; Asuka Takumi-Kobayashi; Takeshi Honda; Akihito Yamaguchi, Feb. 2009, MICROBIOLOGY-SGM, 155, Pt 2, 541, 550, Scientific journal

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• Indole enhances acid resistance in Escherichia coli, Hidetada Hirakawa; Mitsuko Hayashi-Nishino; Akihito Yamaguchi; Kunihiko Nishino, Sep. 2010, MICROBIAL PATHOGENESIS, 49, 3, 90, 94, Scientific journal

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• Impact of the RNA chaperone Hfq on multidrug resistance in Escherichia coli, Junko Yamada; Seiji Yamasaki; Hidetada Hirakawa; Mitsuko Hayashi-Nishino; Akihito Yamaguchi; Kunihiko Nishino, May 2010, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 65, 5, 853, 858, Scientific journal

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• N-acetyl-d-glucosamine induces the expression of multidrug exporter genes, mdtEF, via catabolite activation in Escherichia coli, Hidetada Hirakawa; Yoshihiko Inazumi; Yasuko Senda; Asuka Kobayashi; Takahiro Hirata; Kunihiko Nishino; Akihito Yamaguchi, Aug. 2006, JOURNAL OF BACTERIOLOGY, 188, 16, 5851, 5858, Scientific journal

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• Growth phase-dependent expression of drug exporters in Escherichia coli and its contribution to drug tolerance, Asuka Kobayashi; Hidetada Hirakawa; Takahiro Hirata; Kunihiko Nishino; Akihito Yamaguchi, Aug. 2006, JOURNAL OF BACTERIOLOGY, 188, 16, 5693, 5703, Scientific journal

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• Indole induces the expression of multidrug exporter genes in Escherichia coli, H Hirakawa; Y Inazumi; T Masaki; T Hirata; A Yamaguchi, Feb. 2005, MOLECULAR MICROBIOLOGY, 55, 4, 1113, 1126, Scientific journal

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• Identification of a p-Coumarate Degradation Regulon in Rhodopseudomonas palustris by Xpression, an Integrated Tool for Prokaryotic RNA-Seq Data Processing, Somsak Phattarasukol; Matthew C. Radey; Colin R. Lappala; Yasuhiro Oda; Hidetada Hirakawa; Mitchell J. Brittnacher; Caroline S. Harwood, Oct. 2012, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78, 19, 6812, 6818, Scientific journal

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• Anaerobic p-Coumarate Degradation by Rhodopseudomonas palustris and Identification of CouR, a MarR Repressor Protein That Binds p-Coumaroyl Coenzyme A, Hidetada Hirakawa; Amy L. Schaefer; E. Peter Greenberg; Caroline S. Harwood, Apr. 2012, JOURNAL OF BACTERIOLOGY, 194, 8, 1960, 1967, Scientific journal

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• Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression, Hidetada Hirakawa; Caroline S. Harwood; Kieran B. Pechter; Amy L. Schaefer; E. Peter Greenberg, Jul. 2012, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, 30, 12141, 12146, Scientific journal

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• Roles of TolC-dependent multidrug transporters of Escherichia coli in resistance to beta-lactams, K Nishino; J Yamada; H Hirakawa; T Hirata; A Yamaguchi, Sep. 2003, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 47, 9, 3030, 3033, Scientific journal

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• beta-Lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli, H Hirakawa; K Nishino; J Yamada; T Hirata; A Yamaguchi, Oct. 2003, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 52, 4, 576, 582, Scientific journal

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• Comprehensive studies of drug resistance mediated by overexpression of response regulators of two-component signal transduction systems in Escherichia coli, H Hirakawa; K Nishino; T Hirata; A Yamaguchi, Mar. 2003, JOURNAL OF BACTERIOLOGY, 185, 6, 1851, 1856, Scientific journal

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• A novel hydroxylase from Catharanthus roseus participating in the hydroxylation of 2-hydroxybenzoic acid, K Shimoda; N Kubota; T Sano; H Hirakawa; T Hirata, Aug. 2004, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 98, 2, 67, 70, Scientific journal

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• Activity of the Rhodopseudomonas palustris p-Coumaroyl-Homoserine Lactone-Responsive Transcription Factor RpaR, Hidetada Hirakawa; Yasuhiro Oda; Somsak Phattarasukol; Christopher D. Armour; John C. Castle; Christopher K. Raymond; Colin R. Lappala; Amy L. Schaefer; Caroline S. Harwood; E. Peter Greenberg, May 2011, JOURNAL OF BACTERIOLOGY, 193, 10, 2598, 2607, Scientific journal

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• Roles of CytR, an anti-activator of cyclic-AMP receptor protein (CRP) on flagellar expression and virulence in uropathogenic Escherichia coli., Hirakawa H; Takita A; Kato M; Mizumoto H; Tomita H, Oct. 2019, Biochemical and biophysical research communications

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• [New class of Acyl-homoserine lactone quorum sensing signals]., Hirakawa H; Tomita H, 2013, Nihon saikingaku zasshi. Japanese journal of bacteriology, 68, 4, 325, 335

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• Biotransformation of phenolic compounds by the cultured cells of Catharanthus roseus, Kei Shimoda; Shin-ya Yamane; Hidetada Hirakawa; Shinji Ohta; Toshifumi Hirata, 18 Feb. 2002, Journal of Molecular Catalysis - B Enzymatic, 16, 5-6, 275, 281, Scientific journal

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• 嫌気環境における大腸菌群のホスホマイシン輸送体発現制御メカニズムの解析, ;;;, May 2016, 64, Suppl.A, 206
• 嫌気環境におけるホスホマイシン抗菌活性増大メカニズムの解析, ;;;, May 2016, 64, 3, 592
• 多剤耐性菌の制御に向けた研究の新展開　環境に依存した大腸菌のホスホマイシン抗菌活性変動メカニズム, 平川 秀忠, Aug. 2016, 159回, 213
• 鉄欠乏環境における尿路病原性大腸菌(UPEC)の膀胱上皮細胞侵入とマイクロコロニー形成促進機構, ;;, Aug. 2016, 66, 3, 250
• バイオフィルム感染症におけるパーシスタンス現象の解明と対策　鉄の恒常性破綻による尿路病原性大腸菌(UPEC)のバイオフィルム形成促進, ;;;, Feb. 2016, 71, 1, 42
• 薬剤耐性の基礎研究　嫌気環境下におけるホスホマイシン抗菌活性増大メカニズムの解析, ;;;, Feb. 2016, 71, 1, 47
• 鉄欠乏環境における尿路病原性大腸菌(UPEC)の膀胱上皮細胞内マイクロコロニー形成と抗菌剤抵抗性増大機構, ;;, Jan. 2017, 65, 1, 101
• 【多剤耐性菌の制御に向けた研究の新展開】環境に依存した大腸菌のホスホマイシン抗菌活性変動メカニズム, 平川 秀忠, Mar. 2017, 70, 3, 179
• 細菌の集団形成とその制御機構の新展開　尿路病原性大腸菌(Uropathogenic E.coli:UPEC)の鉄欠乏応答と膀胱上皮細胞内におけるバイオフィルム形成, 平川 秀忠, Feb. 2017, 72, 1, 41
• The Tol-Pal System of Uropathogenic Escherichia coli Is Responsible for Optimal Internalization Into and Aggregation Within Bladder Epithelial Cells, Colonization of the Urinary Tract of Mice, and Bacterial Motility., Hirakawa Hidetada;Suzue Kazutomo;Kurabayashi Kumiko;Tomita Haruyoshi, Aug. 2019, Frontiers in microbiology, 10

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• Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter., Hirakawa Hidetada;Kurabayashi Kumiko;Tanimoto Koichi;Tomita Haruyoshi, Aug. 2018, Frontiers in microbiology, 9

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• New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species., Nomura Takahiro;Hashimoto Yusuke;Kurushima Jun;Hirakawa Hidetada;Tanimoto Koichi;Zheng Bo;Ruan Genjie;Xue Feng;Liu Jian;Hisatsune Junzo;Sugai Motoyuki;Tomita Haruyoshi, Jan. 2018, Journal of microbiological methods, 145

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• Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions., Kurabayashi Kumiko;Tanimoto Koichi;Tomita Haruyoshi;Hirakawa Hidetada, Mar. 2017, Frontiers in microbiology, 8

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• Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli., Kurabayashi Kumiko;Agata Tomohiro;Asano Hirofumi;Tomita Haruyoshi;Hirakawa Hidetada, Oct. 2016, Infection and immunity, 84, 11

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• Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions., Kurabayashi Kumiko;Tanimoto Koichi;Fueki Shinobu;Tomita Haruyoshi;Hirakawa Hidetada, Jul. 2015, Antimicrobial agents and chemotherapy, 59, 10

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• Identification of a second two-component signal transduction system that controls fosfomycin tolerance and glycerol-3-phosphate uptake., Kurabayashi Kumiko;Hirakawa Yuko;Tanimoto Koichi;Tomita Haruyoshi;Hirakawa Hidetada, Dec. 2014, Journal of bacteriology, 197, 5

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• [New class of Acyl-homoserine lactone quorum sensing signals]., Hirakawa Hidetada;Tomita Haruyoshi, Nihon saikingaku zasshi. Japanese journal of bacteriology, 68, 4

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• Role of the CpxAR two-component signal transduction system in control of fosfomycin resistance and carbon substrate uptake., Kurabayashi Kumiko;Hirakawa Yuko;Tanimoto Koichi;Tomita Haruyoshi;Hirakawa Hidetada, Oct. 2013, Journal of bacteriology, 196, 2

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• Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance., Hirakawa Hidetada;Tomita Haruyoshi, May 2013, Frontiers in microbiology, 4

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• 尿路病原性大腸菌(Uropathogenic E.coli:UPEC)の膀胱上皮細胞内マイクロコロニー形成と運動性におけるペリプラズム局在蛋白TolBの機能解析, ;;, Aug. 2017, 67, 3, 275
• A new class of Acyl-homoserine lactone quorum sensing signals, HIRAKAWA Hidetada;TOMITA Haruyoshi, 2013, Nippon Saikingaku Zasshi, 68, 4, 325, 335

  DOI
• 嫌気環境における緑膿菌のホスホマイシンに対する感受性増大機構の解析, ;;, Jan. 2019, 67, 1, 121
• 国内医療機関の入院患者より分離された、非常に稀なVanD型バンコマイシン耐性E.faeciumに関する分子生物学的解析, ;;;, Jan. 2019, 67, 1, 119
• 群馬県内で分離されたAcinetobacter属菌について, ;;;;, Dec. 2018, 29, Suppl.1, 400
• 国内で分離されたVanD型バンコマイシン耐性E.faeciumに関する分子遺伝学的解析, ;;;;, Dec. 2018, 29, Suppl.1, 397
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞内バイオフィルム形成と鞭毛形成因子TolBの機能解析, ;, Jul. 2018, 32回, 29
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染におけるペリプラズム局在蛋白質TolBの役割, ;;, Feb. 2018, 73, 1, 103
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染におけるペリプラズム局在蛋白質TolBの機能解析, ;;, May 2018, 66, 3, 452
• 尿路病原性大腸菌(uropathogenic E.coli:UPEC)の病原性発現に関与する二成分制御系の解析, ;;;, Aug. 2019, 69, 3, 304
• AMRの観点から薬剤耐性菌感染症に関するtranslational researchを考える　バイオフィルムを標的とした薬剤耐性大腸菌感染症に対する新たな治療戦略創出のためのアプローチ, ;, Mar. 2019, 93, 臨増, 307
• 尿路病原性大腸菌(UPEC)のマイクロコロニー形成と鞭毛発現抑制因子CytRの解析, ;, Mar. 2019, 74, 1, 87
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞内バイオフィルム形成と鞭毛形成因子TolBの機能解析, ;, May 2019, 32, 33
• The Two-Component System CpxRA Represses Salmonella Pathogenicity Island 2 by Directly Acting on the ssrAB Regulatory Operon, Leon-Montes, Nancy;Nava-Galeana, Jessica;Rodriguez-Valverde, Diana;Soria-Bustos, Jorge;Rosales-Reyes, Roberto;Rivera-Gutierrez, Sandra;Hirakawa, Hidetada;Ares, Miguel A.;Bustamante, Victor H.;De la Cruz, Miguel A., 2022, MICROBIOLOGY SPECTRUM

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• Editorial: Gram-Negative Pathogenesis, Hirakawa, Hidetada;Bordi, Christophe;Tomita, Haruyoshi, 2021, FRONTIERS IN MICROBIOLOGY, 12

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• Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter, Hirakawa, Hidetada;Kurabayashi, Kumiko;Tanimoto, Koichi;Tomita, Haruyoshi, 2018, FRONTIERS IN MICROBIOLOGY, 9

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• Novel Multidrug-Resistant Enterococcal Mobile Linear Plasmid pELF1 Encoding vanA and vanM Gene Clusters From a Japanese Vancomycin-Resistant Enterococci Isolate., Hashimoto Yusuke;Taniguchi Makoto;Uesaka Kazuma;Nomura Takahiro;Hirakawa Hidetada;Tanimoto Koichi;Tamai Kiyoko;Ruan Genjie;Zheng Bo;Tomita Haruyoshi, Nov. 2019, Frontiers in microbiology, 10

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• First Report of the Local Spread of Vancomycin-Resistant Enterococci Ascribed to the Interspecies Transmission of a vanA Gene Cluster-Carrying Linear Plasmid., Hashimoto Yusuke;Kita Izumi;Suzuki Masato;Hirakawa Hidetada;Ohtaki Hirofumi;Tomita Haruyoshi, Apr. 2020, mSphere, 5, 2

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• In vitro activity of AST-120 that suppresses indole signaling in Escherichia coli, which attenuates drug tolerance and virulence., Hirakawa Hidetada;Uchida Motoyuki;Kurabayashi Kumiko;Nishijima Fuyuhiko;Takita Ayako;Tomita Haruyoshi, Apr. 2020, PloS one, 15, 4

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• Isolation of Serratia fonticola Producing FONA, a Minor Extended-Spectrum β-Lactamase (ESBL), from Imported Chicken Meat in Japan., Tanimoto Koichi;Nomura Takahiro;Hashimoto Yusuke;Hirakawa Hidetada;Watanabe Haruo;Tomita Haruyoshi, Aug. 2020, Japanese journal of infectious diseases, 74, 1

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• Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli., Hirakawa Hidetada;Suzue Kazutomo;Takita Ayako;Awazu Chikako;Kurushima Jun;Tomita Haruyoshi, Sep. 2020, Scientific reports, 10, 1

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• Progress Overview of Bacterial Two-Component Regulatory Systems as Potential Targets for Antimicrobial Chemotherapy., Hirakawa Hidetada;Kurushima Jun;Hashimoto Yusuke;Tomita Haruyoshi, Sep. 2020, Antibiotics (Basel, Switzerland), 9, 10

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• Roles of OmpX, an Outer Membrane Protein, on Virulence and Flagellar Expression in Uropathogenic Escherichia coli., Hirakawa Hidetada;Suzue Kazutomo;Takita Ayako;Kamitani Wataru;Tomita Haruyoshi, May 2021, Infection and immunity, 89, 6

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• Adsorption of Phenazines Produced by Pseudomonas aeruginosa Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity., Hirakawa Hidetada;Takita Ayako;Uchida Motoyuki;Kaneko Yuka;Kakishima Yuto;Tanimoto Koichi;Kamitani Wataru;Tomita Haruyoshi, Apr. 2021, Antibiotics (Basel, Switzerland), 10, 4

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• cAMP Receptor Protein Positively Regulates the Expression of Genes Involved in the Biosynthesis of Klebsiella oxytoca Tilivalline Cytotoxin., Diana Rodríguez-Valverde, Nancy León-Montes, Jorge Soria-Bustos, Jessica Martínez-Cruz, Ricardo González-Ugalde, Sandra Rivera-Gutiérrez, Jorge A González-Y-Merchand, Roberto Rosales-Reyes, Lázaro García-Morales, Hidetada Hirakawa, James G Fox, Jorge A Girón, Miguel A De la Cruz, Miguel A Ares, Sep. 2021, Frontiers in microbiology, 12

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• Roles of OmpA in Type III Secretion System-Mediated Virulence of Enterohemorrhagic Escherichia coli., Hirakawa Hidetada;Suzue Kazutomo;Takita Ayako;Tomita Haruyoshi, Nov. 2021, Pathogens (Basel, Switzerland), 10, 11

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• Editorial: Gram-Negative Pathogenesis., Hirakawa Hidetada;Bordi Christophe;Tomita Haruyoshi, Dec. 2021, Frontiers in microbiology, 12

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• Elucidation of host diversity of the VanD-carrying genomic islands in enterococci and anaerobes., Hashimoto Yusuke;Hisatsune Junzo;Suzuki Masato;Kurushima Jun;Nomura Takahiro;Hirakawa Hidetada;Kojima Naoko;Ono Yuichi;Hasegawa Yutaka;Tanimoto Koichi;Sugai Motoyuki;Tomita Haruyoshi, Jan. 2022, JAC-antimicrobial resistance, 4, 1

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• Roles of the Tol/Pal System in Bacterial Pathogenesis and Its Application to Antibacterial Therapy., Hirakawa Hidetada;Suzue Kazutomo;Tomita Haruyoshi, Mar. 2022, Vaccines, 10, 3

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• A Macroporous Magnesium Oxide-Templated Carbon Adsorbs Shiga Toxins and Type III Secretory Proteins in Enterohemorrhagic Escherichia coli, Which Attenuates Virulence., Hirakawa Hidetada;Suzue Kazutomo;Uchida Motoyuki;Takita Ayako;Kamitani Wataru;Tomita Haruyoshi, May 2022, Frontiers in microbiology, 13

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• 細菌感染症の治療薬創出に挑む-細菌学者は何ができるのか?-　抗感染症薬としての吸着剤の可能性, ;, Feb. 2023, 78, 1, 33
• The PapB/FocB family protein TosR acts as a positive regulator of flagellar expression and is required for optimal virulence of uropathogenic Escherichia coli., Hirakawa Hidetada;Shimokawa Mizuki;Noguchi Koshi;Tago Minori;Matsuda Hiroshi;Takita Ayako;Suzue Kazutomo;Tajima Hirotaka;Kawagishi Ikuro;Tomita Haruyoshi, Jul. 2023, Frontiers in microbiology, 14

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• Inactivation of ackA and pta Genes Reduces GlpT Expression and Susceptibility to Fosfomycin in Escherichia coli., Hirakawa Hidetada;Takita Ayako;Sato Yumika;Hiramoto Suguru;Hashimoto Yusuke;Ohshima Noriyasu;Minamishima Yoji A;Murakami Masami;Tomita Haruyoshi, May 2023, Microbiology spectrum, 11, 3

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• Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades., Hashimoto Yusuke;Suzuki Masato;Kobayashi Sae;Hirahara Yuki;Kurushima Jun;Hirakawa Hidetada;Nomura Takahiro;Tanimoto Koichi;Tomita Haruyoshi, Mar. 2023, Antimicrobial agents and chemotherapy, 67, 4

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• Exploration of the protein-dependent mechanism of Lactobacillus crispatus GAI98322 to prevent recurrent cystitis., Watanabe Tomofumi;Sadahira Takuya;Hirakawa Hidetada;Huang Peng;Zhou Tianyun;Iwata Takehiro;Sekito Takanori;Ishii Ayano;Watanabe Masami;Araki Motoo, Jun. 2023, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 29, 10

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MISC

• Identification of a Second Two-Component Signal Transduction System That Controls Fosfomycin Tolerance and Glycerol-3-Phosphate Uptake, Kumiko Kurabayashi; Yuko Hirakawa; Koichi Tanimoto; Haruyoshi Tomita; Hidetada Hirakawa, Mar. 2015, JOURNAL OF BACTERIOLOGY, 197, 5, 861, 871

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• BadR and BadM Proteins Transcriptionally Regulate Two Operons Needed for Anaerobic Benzoate Degradation by Rhodopseudomonas palustris, Hidetada Hirakawa; Yuko Hirakawa; E. Peter Greenberg; Caroline S. Harwood, Jul. 2015, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81, 13, 4253, 4262

  DOI
• BadR and BadM Proteins Transcriptionally Regulate Two Operons Needed for Anaerobic Benzoate Degradation by Rhodopseudomonas palustris, Hidetada Hirakawa; Yuko Hirakawa; E. Peter Greenberg; Caroline S. Harwood, Jul. 2015, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81, 13, 4253, 4262

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• Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions, Kumiko Kurabayashi; Koichi Tanimoto; Shinobu Fueki; Haruyoshi Tomita; Hidetada Hirakawa, Oct. 2015, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59, 10, 6352, 6360

  DOI
• Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Fosfomycin Susceptibility in Escherichia coli under Anaerobic Conditions, Kumiko Kurabayashi; Koichi Tanimoto; Shinobu Fueki; Haruyoshi Tomita; Hidetada Hirakawa, Oct. 2015, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59, 10, 6352, 6360

  DOI
• Identification of a p-Coumarate Degradation Regulon in Rhodopseudomonas palustris by Xpression, an Integrated Tool for Prokaryotic RNA-Seq Data Processing, Somsak Phattarasukol; Matthew C. Radey; Colin R. Lappala; Yasuhiro Oda; Hidetada Hirakawa; Mitchell J. Brittnacher; Caroline S. Harwood, Oct. 2012, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78, 19, 6812, 6818

  DOI
• Identification of a p-Coumarate Degradation Regulon in Rhodopseudomonas palustris by Xpression, an Integrated Tool for Prokaryotic RNA-Seq Data Processing, Somsak Phattarasukol; Matthew C. Radey; Colin R. Lappala; Yasuhiro Oda; Hidetada Hirakawa; Mitchell J. Brittnacher; Caroline S. Harwood, Oct. 2012, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78, 19, 6812, 6818

  DOI
• Anaerobic p-Coumarate Degradation by Rhodopseudomonas palustris and Identification of CouR, a MarR Repressor Protein That Binds p-Coumaroyl Coenzyme A, Hidetada Hirakawa; Amy L. Schaefer; E. Peter Greenberg; Caroline S. Harwood, Apr. 2012, JOURNAL OF BACTERIOLOGY, 194, 8, 1960, 1967

  DOI
• Anaerobic p-Coumarate Degradation by Rhodopseudomonas palustris and Identification of CouR, a MarR Repressor Protein That Binds p-Coumaroyl Coenzyme A, Hidetada Hirakawa; Amy L. Schaefer; E. Peter Greenberg; Caroline S. Harwood, Apr. 2012, JOURNAL OF BACTERIOLOGY, 194, 8, 1960, 1967

  DOI
• Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression, Hidetada Hirakawa; Caroline S. Harwood; Kieran B. Pechter; Amy L. Schaefer; E. Peter Greenberg, Jul. 2012, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, 30, 12141, 12146

  DOI
• Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression, Hidetada Hirakawa; Caroline S. Harwood; Kieran B. Pechter; Amy L. Schaefer; E. Peter Greenberg, Jul. 2012, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, 30, 12141, 12146

  DOI
• Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli, Kumiko Kurabayashi; Tomohiro Agata; Hirofumi Asano; Haruyoshi Tomita; Hidetada Hirakawa, Nov. 2016, INFECTION AND IMMUNITY, 84, 11, 3220, 3231

  DOI
• Fur Represses Adhesion to, Invasion of, and Intracellular Bacterial Community Formation within Bladder Epithelial Cells and Motility in Uropathogenic Escherichia coli, Kumiko Kurabayashi; Tomohiro Agata; Hirofumi Asano; Haruyoshi Tomita; Hidetada Hirakawa, Nov. 2016, INFECTION AND IMMUNITY, 84, 11, 3220, 3231

  DOI
• Role of the CpxAR Two-Component Signal Transduction System in Control of Fosfomycin Resistance and Carbon Substrate Uptake, Kumiko Kurabayashi; Yuko Hirakawa; Koichi Tanimoto; Haruyoshi Tomita; Hidetada Hirakawa, Jan. 2014, JOURNAL OF BACTERIOLOGY, 196, 2, 248, 256

  DOI
• Role of the CpxAR Two-Component Signal Transduction System in Control of Fosfomycin Resistance and Carbon Substrate Uptake, Kumiko Kurabayashi; Yuko Hirakawa; Koichi Tanimoto; Haruyoshi Tomita; Hidetada Hirakawa, Jan. 2014, JOURNAL OF BACTERIOLOGY, 196, 2, 248, 256

  DOI
• 国内で分離されたVanD型バンコマイシン耐性E.faeciumに関する分子遺伝学的解析, 橋本 佑輔; 野村 隆浩; 平川 秀忠; 谷本 弘一; 富田 治芳, Dec. 2018, 日本臨床微生物学会雑誌, 29, Suppl.1, 397, 397
• 群馬県内で分離されたAcinetobacter属菌について, 野村 隆浩; 谷本 弘一; 平川 秀忠; 村上 正巳; 富田 治芳, Dec. 2018, 日本臨床微生物学会雑誌, 29, Suppl.1, 400, 400
• Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic Escherichia coli (EHEC) by Elevating the Expression of glpT and uhpT under Anaerobic Conditions, Kumiko Kurabayashi; Koichi Tanimoto; Haruyoshi Tomita; Hidetada Hirakawa, Mar. 2017, FRONTIERS IN MICROBIOLOGY, 8, 426

  DOI
• New colony multiplex PCR assays for the detection and discrimination of vancomycin-resistant enterococcal species, Takahiro Nomura; Yusuke Hashimoto; Jun Kurushima; Hidetada Hirakawa; Koichi Tanimoto; Bo Zheng; Genjie Ruan; Feng Xue; Jian Liu; Junzo Hisatsune; Motoyuki Sugai; Haruyoshi Tomita, Feb. 2018, Journal of Microbiological Methods, 145, 69, 72

  DOI
• Identification of a second two-component signal transduction system that controls fosfomycin tolerance and glycerol-3-phosphate uptake, Kumiko Kurabayashi; Yuko Hirakawa; Haruyoshi Tanimoto; H. Koichi Hirakawa; Hidetada Hirakawa, 2015, Journal of Bacteriology, 197, 5, 861, 871

  DOI
• Interference of bacterial cell-to-cell communication: A new concept of antimicrobial chemotherapy breaks antibiotic resistance, Hidetada Hirakawa; Haruyoshi Tomita, 2013, Frontiers in Microbiology, 4, MAY, 114, Book review

  DOI
• Cooperative actions of CRP-cAMP and FNR increase the fosfomycin susceptibility of enterohaemorrhagic Escherichia coli (EHEC) by elevating the expression of glpT and uhpT under anaerobic conditions, Kumiko Kurabayashi; Koichi Tanimoto; Haruyoshi Tomita; Hidetada Hirakawa, 16 Mar. 2017, Frontiers in Microbiology, 8, 426

  DOI
• Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance, Hirakawa, Hidetada; Tomita, Haruyoshi, 2013, 4, 114

  DOI

Books etc

• バイオフィルム形成に見る“エリート主義”の細菌社会, 2013
• 新規ホモセリンラクトンクオラムセンシングシグナル, 2013
• 新しい細菌オートインデューサーによるクオラムセンシング機構, 2014
• インドール型オートインデューサーと大腸菌の社会活動, 2015

Presentations

• マクロ孔型の多孔質炭素を利用した腸管出血性大腸菌の志賀毒素と3型分泌蛋白質の吸着による病原性抑制, 平川秀忠, 第５０回薬剤耐性菌研究会, Nov. 2021
• マクロ孔吸着炭を利用した腸管出血性大腸菌の志賀毒素と3型分泌蛋白質の吸着および、病原性抑制, 平川秀忠, 第６８回日本化学療法学会東日本支部総会, Oct. 2021
• ROLES OF THE TOL/PAL SYSTEM ON THE PRODUCTION OF FLAGELLAR AND THE TYPE III SECRETION SYSTEM MACHINERY, Hidetada Hirakawa, Bacterial Locomotion and Signal Transduction (BLAST), Jan. 2021, English, United States, International conference
• 若手研究者支援シンポジウム「シアトルで私が得たこと学んだこと」, 平川秀忠, 第９４回日本細菌学会総会, Mar. 2021, Japanese
• マクロ孔型多孔質炭素を利用した緑膿菌の細胞外病原性因子の吸着と弱毒化, 平川秀忠, 第４５回日本分子生物学会年会, 01 Dec. 2022
• マクロ孔型吸着炭を利用した緑膿菌の病原性因子の吸着と弱毒化, 平川秀忠, 第５７回緑膿菌感染症研究会, 16 Feb. 2023
• 抗感染症薬としての吸着剤の可能性, 平川秀忠, 第９６回日本細菌学会総会, 18 Mar. 2023
• 尿路病原性大腸菌(UPEC)のマイクロコロニー形成と鞭毛形成因子TolBの機能解析, 平川 秀忠, 第101回日本細菌学会関東支部総会, Oct. 2018, Japanese, Domestic conference
• 嫌気環境における緑膿菌のホスホマイシンに対する感受性増大機構の解析, 平川 秀忠, 第65回日本化学療法学会東日本支部総会, Oct. 2018, Japanese, Domestic conference
• 尿路病原性大腸菌の病原性因子Tol-Palシステムの機能解析, 平川 秀忠, 第31回微生物シンポジウム, Aug. 2019, Japanese, Domestic conference
• 細胞外シチジンによる尿路病原性大腸菌のマイクロコロニー形成と鞭毛遺伝子発現誘導機構の解析, 平川 秀忠, 第102回日本細菌学会関東支部総会, Oct. 2019, Japanese, Domestic conference
• 経口吸着炭AST-120による大腸菌の薬剤耐性と病原性抑制効果の検討, 平川 秀忠, 第66回日本化学療法学会東日本支部総会, Oct. 2019, Japanese, Domestic conference
• 尿路病原性大腸菌(UPEC)のマイクロコロニー形成と鞭毛発現抑制因子CytRの解析, 平川 秀忠, 第92回日本細菌学会総会, Apr. 2019, Japanese, Domestic conference
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞内バイオフィルム形成と 鞭毛形成因子TolBの機能解析, 平川 秀忠, 第32回日本バイオフィルム学会学術集会, Jul. 2018, Japanese, Domestic conference
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染における ペリプラズム局在蛋白質TolBの役割, 平川 秀忠, 第91回日本細菌学会総会, Mar. 2018, Japanese, Domestic conference
• 尿路病原性大腸菌のマイクロコロニー形成におけるTolBの機能, 平川 秀忠, 第100回日本細菌学会関東支部総会, Oct. 2017, Japanese, Domestic conference
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞感染における ペリプラズム局在蛋白質TolBの機能解析, 平川 秀忠, 第64回日本化学療法学会東日本支部総会, Oct. 2017, Japanese, Domestic conference
• 嫌気環境における大腸菌のホスホマイシン輸送体発現と 抗菌活性増大メカニズムの解析, 平川 秀忠, 第45回薬剤耐性菌研究会, Oct. 2016, Japanese, Domestic conference
• 鉄欠乏環境下における尿路病原性大腸菌(Uropathogenic E. coli: UPEC)のI型線毛発現誘導と膀胱上皮細胞侵入、マイクロコロニー形成促進機構の解析, 平川 秀忠, 第99回日本細菌学会関東支部総会, Oct. 2016, Japanese, Domestic conference
• 鉄欠乏環境における尿路病原性大腸菌(UPEC)の膀胱上皮細胞内マイクロコロニー形成と抗菌剤抵抗性増大機構, 平川 秀忠, 第63回日本化学療法学会東日本支部総会, Oct. 2016, Japanese, Domestic conference
• 嫌気環境における大腸菌群のホスホマイシン輸送体発現制御メカニズムの解析, 平川 秀忠, 第64回日本化学療法学会総会, Jun. 2016, Japanese, Domestic conference
• 嫌気環境におけるホスホマイシン抗菌活性の分子メカニズムの解析, 平川 秀忠, 第63回日本化学療法学会総会, Jun. 2015, Japanese, Domestic conference
• 嫌気環境におけるホスホマイシン抗菌活性増大メカニズムの解析, 平川 秀忠, 第62回日本化学療法学会東日本支部総会, Oct. 2015, Japanese, Domestic conference
• 嫌気環境下での大腸菌群に対するホスホマイシン抗菌活性増大メカニズム, 平川 秀忠, 第44回薬剤耐性菌研究会, Oct. 2015, Japanese, Domestic conference
• 二成分情報伝達系を介した腸管出血性大腸菌O157のホスホマイシン耐性と炭素源獲得の可逆的制御, 平川 秀忠, 日本農芸化学会2014年度大会, Mar. 2014, Japanese, Domestic conference
• トリメチルアミンＮオキシド応答性Torシステムを介したホスホマイシン耐性誘導, 平川 秀忠, 第４３回薬剤耐性菌研究会, Oct. 2014, Japanese, Domestic conference
• Trimethylamine-N-oxide感知応答Torシステムによる腸管出血性大腸菌O157のホスホマイシン耐性誘導, 平川 秀忠, 第６１回日本化学療法学会東日本支部総会, Oct. 2014, Japanese, Domestic conference
• 二成分情報伝達系CpxARによる腸管出血性大腸菌O157のホスホマイシン抵抗性と炭素源獲得の制御, 平川 秀忠, 第９６回日本細菌学会関東支部総会, Oct. 2013, Japanese, Domestic conference
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞侵入とマイクロコロニー形成におけるインドールシグナルの役割, 平川 秀忠, 第８８回日本細菌学会総会, Mar. 2015, Japanese, Domestic conference
• Quorum sensingの新規抑制因子Non-coding regulatory anti-sense RNA, 平川 秀忠, 第95回日本細菌学会関東支部総会, Oct. 2012, Japanese, Domestic conference
• 環境感知応答システムに依存した腸管出血性大腸菌O157のホスホマイシン抵抗性と炭素源獲得のトレードオフ, 平川 秀忠, 第４２回薬剤耐性菌研究会, Oct. 2013, Japanese, Domestic conference
• 細菌のQuorum sensing情報伝達を抑制するNon-coding regulatory anti-sense, 平川 秀忠, 第59回北関東医学会総会, Sep. 2012, Japanese, Domestic conference
• 光合成土壌細菌Rhodopseudomonas palustrisにおける安息香酸化合物の嫌気的分解とその制御因子BadRの機能解析, 平川 秀忠, 日本農芸化学会2013年度大会, Mar. 2013, Japanese, Domestic conference
• 光合成細菌のQuorum sensingとその制御因子Anti-sense RNA, 平川 秀忠, 第86回日本細菌学会総会, Feb. 2013, Japanese, Domestic conference
• Comprehensive Analysis of Two-component Signal Transduction System Induced Multidrug Resistance in Escherichia coli, HIRAKAWA Hidetada, American Society for Microbiology General Meeting, May 2003, English, International conference
• Regulation of Drug Exporter Genes by Intercellular Signal Molecules in Escherichia coli, HIRAKAWA Hidetada, American Society for Microbiology General Meeting, May 2004, English, International conference
• Indole Sensing Mechanisms that Control Growth Phase-dependent Expression of Xenobiotic Exporter Genes, HIRAKAWA Hidetada, American Society for Microbiology General Meeting, Jun. 2005, English, International conference
• Roles of Indole Signaling and Intercellular Signal Transduction on Type III Secretion System-dependent Pathogenicity in EHEC, HIRAKAWA Hidetada, ASM conference Cell-Cell Communication in Bacteria, Oct. 2007, English, International conference
• RpaR, a receptor for a novel class of quorum sensing signals, functions as an activator in Rhodopseudomonas palustris, HIRAKAWA Hidetada, American Society for Microbiology General Meeting, May 2009, English, International conference
• RpaR, a receptor for the aryl-HSL produced by Rhodopseudomonas palustris, HIRAKAWA Hidetada, Microbial Adhesion and Signal Transduction, Gordon Research Conferences, Jul. 2009, English, International conference
• CouR, a MarR transcriptional regulator that binds p-coumaroyl-CoA, HIRAKAWA Hidetada, American Society for Microbiology General Meeting, May 2010, English, International conference
• A Regulatory rpaR Antisense RNA in Rhodopseudomonas palustris: Dependence and Influence on Quorum Sensing, HIRAKAWA Hidetada, ASM conference Cell-Cell Communication in Bacteria, Nov. 2011, English, International conference
• A Large Regulatory rpaR Antisense RNA in Rhodopseudomonas palustris: Dependence and Influence on Quorum Sensing, HIRAKAWA Hidetada, Microbial Adhesion and Signal Transduction, Gordon Research Conferences, Jul. 2011, English, International conference
• Reversible Control of Fosfomycin Resistance and Carbon Substrate Uptake by Two-component Signal Transduction System, HIRAKAWA Hidetada, American Society for Microbiology 114th General Meeting, May 2014, English, International conference
• Indole Signal Induces Multidrug Tolerance in Uropathogenic Escherichia coli (UPEC, HIRAKAWA Hidetada, 5th ASM Conference on Cell-Cell Communication in Bacteria, Oct. 2014, English, International conference
• Elevated Expression of GlpT and UhpT via FNR Activation Contributes to Increased Susceptibility to Fosfomycin in Enterohaemorrhagic E. coli (EHEC) under Anaerobic Condition, HIRAKAWA Hidetada, ICAAC/ICC 2015, Sep. 2015, English, International conference
• Molecular Mechanism of Fosfomycin Therapy to Anaerobic Microbe Infections, HIRAKAWA Hidetada, World Gene Convention, Nov. 2016, English, International conference
• TolB, the Periplasmic Protein That Controls Flagellar Biosynthesis and the Biofilm Formation in Uropathogenic Escherichia coli (UPEC), HIRAKAWA Hidetada, ASM conference on Biofilms, Oct. 2018, English, International conference
• The tolB gene which encodes the periplasmic protein contributes to the formation of intracellular bacterial communities (IBCs) in uropathogenic Escherichia coli (UPEC), HIRAKAWA Hidetada, ASM conference Cell-Cell Communication in Bacteria, Oct. 2017, English, International conference
• Analysis of the regulation mechanisms of xenobiotic exporters induced by indole in Escherichia coli, 平川 秀忠, 第77回日本生化学会大会, Oct. 2004, Japanese, Domestic conference
• 大腸菌推定二成分情報伝達系遺伝子発現ライブラリ構築と解析, 平川 秀忠, 第75回日本細菌学会総会, Mar. 2002, Japanese, Domestic conference
• 大腸菌二成分情報伝達系による薬剤耐性化機構の解析, 平川 秀忠, 第76回日本細菌学会総会, Mar. 2003, Japanese, Domestic conference
• 二成分情報伝達系を介した大腸菌異物排出蛋白質発現制御ネットワークの解析, 平川 秀忠, 第16回微生物シンポジウム, Aug. 2003, Japanese, Domestic conference
• インドールシグナルによる大腸菌情報伝達ネットワークの解析, 平川 秀忠, 第78回日本細菌学会総会, Mar. 2005, Japanese, Domestic conference
• アシルホモセリンラクトン新規サブタイプと細菌間コミュニケーション, 平川 秀忠, 第７回若手研究者育成のためのワークショップ「若手研究者によるバイオフィルム研究ワークショップ」, Jun. 2013, Japanese, Domestic conference
• 二成分情報伝達系による腸管出血性大腸菌のホスホマイシン抵抗性と炭素源獲得の可逆的制御, 平川 秀忠, 第87回日本細菌学会総会, Mar. 2014, Japanese, Domestic conference
• ふぞろいの遺伝子たち：プレリュード, 平川 秀忠, 第61回北関東医学会総会, Sep. 2014, Japanese, Domestic conference
• 社会形成による大腸菌群の薬剤耐性と病原性制御, 平川 秀忠, 第６６回日本生物工学会大会, Sep. 2014, Japanese, Domestic conference
• 嫌気環境下におけるホスホマイシン抗菌活性増大メカニズムの解析, 平川 秀忠, 第89回日本細菌学会総会, Mar. 2016, Japanese, Domestic conference
• 環境に依存した大腸菌のホスホマイシン抗菌活性変動メカニズム, 平川 秀忠, 第１５９回日本獣医学会学術集会, Sep. 2016, Japanese, Domestic conference
• 尿路病原性大腸菌(Uropathogenic E. coli: UPEC)の鉄欠乏応答と膀胱上皮細胞内におけるバイオフィルム形成, 平川 秀忠, 第90回日本細菌学会総会, Mar. 2017, Japanese, Domestic conference
• 尿路病原性大腸菌(UPEC)の膀胱上皮細胞内におけるIBC形成機構, 平川 秀忠, 第３０回微生物シンポジウム, Aug. 2018, Japanese, Domestic conference
• バイオフィルムを標的とした薬剤耐性大腸菌感染症に対する新たな治療戦略創出のためのアプローチ, 平川 秀忠, 第９３回日本感染症学会総会・学術講演会, Apr. 2019, Japanese, Domestic conference
• Non-translated regulatory anti-sense RNA that affects bacterial quorum sensing activity, International Symposium by ASRLD unit, 2013

Awards

• Mar. 2023, Japan society, Japan
• Student Travel Grant Award, HIRAKAWA Hidetada, American Society for Microbiology, Jun. 2005
• Dec. 2016

Research Projects

• Jul. 2024, Mar. 2027, Principal investigator, Competitive research funding, 24K22200
• Oct. 2023, Mar. 2029, Coinvestigator, Competitive research funding, 23gm1610013s0501
• Oct. 2023, Sep. 2024, Principal investigator, Competitive research funding, 23nk0101674h0001
• Apr. 2019, Mar. 2022, Principal investigator, Competitive research funding
• Aug. 2012, Mar. 2013, Principal investigator, Competitive research funding
• Apr. 2013, Mar. 2015, Principal investigator, Competitive research funding
• Apr. 2017, Mar. 2019, Principal investigator, Competitive research funding
• 2006, 2007, Principal investigator, Competitive research funding
• Studies on the regulatory network of xenobiotic exporters induced by bacterial signal transduction systems, 2003, 2006, Competitive research funding
• 2003, 2006, Competitive research funding
• Apr. 2022, Mar. 2026, Principal investigator, Competitive research funding
• Apr. 2025, Mar. 2027, Principal investigator, Competitive research funding, DNW-25022

Educational Activities

Awards

• Others

Social Contribution

Social Contribution

• 取材協力　(Target:　High school students)
• オンライン教材「微生物たちのお城：バイオフィルム」, 15 Dec. 2020　(Target:　Junior high school students, High school students)

Academic Contribution

• 北関東医学会, Academic society etc
• 日本バイオフィルム学会, Academic society etc
• 日本細菌学会関東支部, Academic society etc
• 第９６回細菌学会総会シンポジウム　細菌感染症の治療薬創出に挑むー細菌学者は何ができるのか？ー, Competition etc, 18 Mar. 2023, 18 Mar. 2023
• 薬剤耐性菌研究会事務局、開催当番, Academic society etc, 11 Nov. 2022, 12 Nov. 2022

Media Coverage

• 抗菌薬が効かない緑膿菌を弱毒化, Myself, Jan. 2023, Paper
• 抗菌薬が効かない緑膿菌を弱毒化, Myself, Oct. 2022, Paper
• 炭素でO157を無毒化？薬開発に期待, Myself, May 2022, Internet
• 群馬大学など、O157の無毒化に成功, Myself, May 2022, Paper
• O157毒素 炭素素材で吸着, Myself, May 2022, Paper
• 群大などのチーム O157を弱毒化, Myself, May 2022, Media report
• O157を特殊な炭素で弱毒化, Myself, May 2022, Media report
• 腸管出血性大腸菌O157ワクチン候補株の作製に成功、治療法の発展に期待, 29 Sep. 2020, Internet
• O157発症せず免疫, 25 Oct. 2020