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YASHIMA Hideaki
Clinical Pharmacology and Thearapeutics
Assistant Professor
Last Updated :2025/05/23

Researcher Profile and Settings

Researcher

  • Name

    YASHIMA Hideaki

Profile and Settings

  • Name

    Yashima, Hideaki

Affiliation

  • Gunma University, Assistant Professor

Research Experience

  • Gunma University University Hospital
  • Gunma University

Research Activities

Published Papers

  • Risk of Falls with Benzodiazepine Receptor Agonists in Combination with Novel hypnotics., Yuya Higuchi, Yuya Ishikawa, Takuya Araki, Yukina Ohshima, Hideaki Yashima, Koujirou Yamamoto, 2023
  • The reductive activity of human liver microsomes for vitamin K epoxides., Masashi Kawano, Takuya Araki, Hideaki Yashima, Tomonori Nakamura, Koujirou Yamamoto., Feb. 2020, Indonesian Journal of Pharmaceutics.
  • Simple and Rapid Method for Determination of Abemaciclib in Human Serum using Supported Liquid Extraction Pretreatment and LC-MS/MS Analysis., Naoto Sekizaki, Hideaki Yashima, Takuya Araki, Koujirou Yamamoto., Dec. 2020, Indonesian Journal of Pharmaceutics.
  • Effect of nicotine- and tar-removed cigarette smoke extract on cancer metastasis., Yuta Takahashi, Takuya Araki, Hideaki Yashima, Ayumu Nagamine, Daisuke Nagano, Kyoko Obayashi, Koujirou Yamamoto., Aug. 2021, Indonesian Journal of Pharmaceutics.
  • Development of a quantitative method for sunitinib N-oxide using LC-MS/MS., Yuya Ishikawa, Takuya Araki, Miki Takenaka Sato, Hideaki Yashima, Daisuke Nagano, Koujirou Yamamoto., Aug. 2021, Indonesian Journal of Pharmaceutics.
  • Comparison of the antiemetic effect of aprepitant/granisetron and palonosetron combined with dexamethasone in gynecological cancer patients treated with paclitaxel and carboplatin combination regimen., K. Obayashi, A. Nagamine, H. Yashima, S. Ohshima, C. Uchiyama, E. Takahashi, Y. Takahashi, T. Araki, K. Yamamoto., May 2022, Die Pharmazie.
  • Review of the treatment of non-small cell lung cancer with gefitinib., Araki T, Yashima H, Shimizu K, et al., Dec. 2012, lin Med Insights Oncol.
  • Prediction and structural equation model of sertraline treatment response in Japanese patients with major depressive disorder, Nishioka, Gentaro; Yashima, Hideaki; Kiuchi, Yuji; Nakamura, Sumiko; Oyamada, Hideto; Ishii, Masakazu; Kudo, Ikuo, Nov. 2013, HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
    DOI
  • Assessment of DDR2, BRAF, EGFR and KRAS mutations as therapeutic targets in non-adenocarcinoma lung cancer patients, Hideaki Yashima, Kimihiro Shimizu, Takuya Araki, Tohru Aomori, Yoichi Ohtaki, Toshiteru Nagashima, Yasuaki Enokida, Jun Atsumi, Tomonori Nakamura, Izumi Takeyoshi, Koujirou Yamamoto, 2014, Molecular and Clinical Oncology
    DOI
  • Prognostic potential of the MDM2 309T > G polymorphism in stage I lung adenocarcinoma, Enokida, Yasuaki; Shimizu, Kimihiro; Atsumi, Jun; Kakegawa, Seiichi; Takase, Yoshiaki; Kaira, Kyoichi; Yashima, Hideaki; Araki, Takuya; Nakazawa, Seshiru; Ohtaki, Yoichi; Nagashima, Toshiteru; Alexander, Lezhava; Usui, Kengo; Ishikawa, Toshihisa; Hayashizaki, Yoshihide; Takeyoshi, Izumi, 2016, CANCER MEDICINE
    DOI
  • 放射性医薬品の取扱に関するアンケート調査報告, ;;;;;;;;;;;;;;;;;, 2019, KAKUIGAKU, 56, 1, 25, 31
    DOI
  • Risk Factors for Low Vancomycin Trough Level in Adult General Ward Inpatients: a Retrospective Cohort Study, Hasegawa Shun;Yashima Hideaki;Takahashi Emiri;Takahashi Yuta;Yamamoto Koujirou;Obayashi Kyoko, Jul. 2020, Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 46, 7, 387, 395
    DOI
  • 黄色ブドウ球菌菌血症に伴う血小板減少症への新規治療戦略および治療薬候補, YASHIMA Hideaki, 2021, Farumashia, 57, 11, 1053, 1053
    DOI
  • 重症患者におけるテイコプラニン負荷投与量の検討, ;;, Jan. 2017, 65, 1, 90
  • 群馬大学医学部附属病院ICUにおける抗菌薬適正使用に関する病棟薬剤師の取り組み, ;;;;, Jan. 2017, 65, 1, 104
  • ボリコナゾール代謝物の測定により薬物代謝能の評価を行った1例, ;;;, Jan. 2017, 91, 1, 78
  • ホスフェニトイン投与後に血中フェニトイン濃度が異常低値を生じた症例, ;;;;;;;;;;, May 2018, 35, 2, 157
  • 患者のQOL向上と薬剤師の関わり(PART I.)　院内製剤　院内製剤点眼液の品質管理の取り組み, ;;;;;, May 2018, 54, 5, 1271
  • V-A ECMOを使用したコルヒチン中毒の一剖検例, ;;;;;;;;;, Sep. 2020, 33, 2, 156
  • 少量の散剤を分包する際の精度, ;;;;;, Dec. 2020, 33, 1, 67
  • 難治性ショックを伴う複数種類の降圧薬中毒に対し集学的治療で救命し得た1例, ;;;;;;;;;, Oct. 2021, 34, 3, 234
  • 乳糖水和物中に含まれる牛乳アレルギー誘引タンパク質の測定系の検討, ;;;, Sep. 2021, 34, 1, 66
  • 少量の散剤を分包した際の分包内重量の評価, ;;;, Sep. 2021, 34, 1, 118
  • 医療薬科学　黄色ブドウ球菌菌血症に伴う血小板減少症への新規治療戦略および治療薬候補, 八島 秀明, Nov. 2021, 57, 11, 1053
  • 【お薬立ちBOOK2022　解剖生理・病態生理から薬学管理へ】病態生理を踏まえた薬物治療・薬学管理へ　甲状腺炎(橋本病)　薬理と薬学管理上の注意点, ;, Mar. 2022, 73, 4, 1151
  • Review of the treatment of non-small cell lung cancer with gefitinib., Araki Takuya;Yashima Hideaki;Shimizu Kimihiro;Aomori Tohru;Hashita Tadahiro;Kaira Kyoichi;Nakamura Tomonori;Yamamoto Koujirou, Dec. 2012, Clinical Medicine Insights. Oncology, 6
    DOI
  • Assessment of DDR2, BRAF, EGFR and KRAS mutations as therapeutic targets in non-adenocarcinoma lung cancer patients., Yashima Hideaki;Shimizu Kimihiro;Araki Takuya;Aomori Tohru;Ohtaki Yoichi;Nagashima Toshiteru;Enokida Yasuaki;Atsumi Jun;Nakamura Tomonori;Takeyoshi Izumi;Yamamoto Koujirou, Jun. 2014, Molecular and clinical oncology, 2, 5
    DOI
  • Prognostic potential of the MDM2 309T>G polymorphism in stage I lung adenocarcinoma., Enokida Yasuaki;Shimizu Kimihiro;Atsumi Jun;Kakegawa Seiichi;Takase Yoshiaki;Kaira Kyoichi;Yashima Hideaki;Araki Takuya;Nakazawa Seshiru;Ohtaki Yoichi;Nagashima Toshiteru;Alexander Lezhava;Usui Kengo;Ishikawa Toshihisa;Hayashizaki Yoshihide;Takeyoshi Izumi, May 2016, Cancer medicine, 5, 8
    DOI
  • 【お薬立ちBOOK2022　解剖生理・病態生理から薬学管理へ】病態生理を踏まえた薬物治療・薬学管理へ　甲状腺炎(橋本病)　薬理と薬学管理上の注意点, ;, Mar. 2022, 73, 4, 1151
  • アベマシクリブ投与中に重度の副作用を発現した2症例におけるアベマシクリブおよび代謝物の解析, ;;;;;;;, May 2022, 39, 2, 147
  • Prediction and structural equation model of sertraline treatment response in Japanese patients with major depressive disorder, Nishioka, Gentaro;Yashima, Hideaki;Kiuchi, Yuji;Nakamura, Sumiko;Oyamada, Hideto;Ishii, Masakazu;Kudo, Ikuo, 2013, HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 28, 6, 576, 585
    DOI
  • Prognostic potential of the MDM2 309T > G polymorphism in stage I lung adenocarcinoma, Enokida, Yasuaki;Shimizu, Kimihiro;Atsumi, Jun;Kakegawa, Seiichi;Takase, Yoshiaki;Kaira, Kyoichi;Yashima, Hideaki;Araki, Takuya;Nakazawa, Seshiru;Ohtaki, Yoichi;Nagashima, Toshiteru;Alexander, Lezhava;Usui, Kengo;Ishikawa, Toshihisa;Hayashizaki, Yoshihide;Takeyoshi, Izumi, 2016, CANCER MEDICINE, 5, 8, 1791, 1801
    DOI
  • A retrospective study to assess the risk of falls due to prescribed drugs in inpatients, Yashima, Hideaki;Araki, Takuya;Shibamiya, Taku;Komatsu, Yasuhiro;Yamamoto, Koujirou, 2018, PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 27, 483, 484
  • 群馬大学医学部附属病院集中治療室における注射薬配合変化回避に向けた取り組み, ;;;;;;;;;, Feb. 2019, 26, Suppl., [P45
  • 副作用の重症度評価が可能なトレーシングレポートの運用に関する評価, ;;;;;;;, May 2022, 5回, 67
  • Target concentration achievement for efficacy and safety of patients with osteosarcoma treated with high-dose methotrexate based on individual pharmacokinetics: A retrospective study, Nagamine, Ayumu;Araki, Takuya;Yashima, Hideaki;Kamimura, Akane;Shiraishi, Takumi;Yanagawa, Takashi;Obayashi, Kyoko;Yamamoto, Koujirou, 2023, ONCOLOGY LETTERS, 25, 2
    DOI
  • Prevention of Postoperative Cognitive Dysfunction by Minocycline in Elderly Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Clinical Trial, Takazawa, Tomonori;Horiuchi, Tatsuo;Orihara, Masaki;Nagumo, Kazuhiro;Tomioka, Akihiro;Ideno, Yuki;Hayashi, Kunihiko;Yashima, Hideaki;Araki, Takuya;Hatayama, Kazuhisa;Terauchi, Masanori;Ikeda, Yoshio;Saito, Shigeru, 2023, ANESTHESIOLOGY, 138, 2, 172, 183
    DOI
  • Risk of exposure of patients' family members to lenalidomide at home, Takahashi, Yuta;Nagamine, Ayumu;Kaneta, Akiko;Yashima, Hideaki;Obayashi, Kyoko;Araki, Takuya;Yamamoto, Koujirou, 2023, EUROPEAN JOURNAL OF HOSPITAL PHARMACY
    DOI
  • アベマシクリブ投与中に重度の副作用を発現した2症例におけるアベマシクリブおよび代謝物の解析, ;;;;;;;, May 2022, 39, 2, 147
  • 鶏卵アレルギーの誘発リスクがあるとされる薬剤中の鶏卵由来タンパク質の分析法の検討, ;;;, Sep. 2022, 35, 1, 125
  • 難治性ショックを伴うβ遮断薬,カルシウム拮抗薬中毒に対し集学的治療で救命し得た1例, ;;;;;;, Feb. 2023, 34, 2, 55
  • 副作用の重症度評価が可能なトレーシングレポートの運用に関する評価, ;;;;;;;, May 2022, 5回, 67
  • 急性期病院における入院患者の転倒イベントと睡眠薬服用の関係, ;;;;, May 2023, 6回, 63
  • Prevention of Postoperative Cognitive Dysfunction by Minocycline in Elderly Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Clinical Trial., Takazawa Tomonori;Horiuchi Tatsuo;Orihara Masaki;Nagumo Kazuhiro;Tomioka Akihiro;Ideno Yuki;Hayashi Kunihiko;Yashima Hideaki;Araki Takuya;Hatayama Kazuhisa;Terauchi Masanori;Ikeda Yoshio;Saito Shigeru, Anesthesiology, 138, 2
    DOI
  • Target concentration achievement for efficacy and safety of patients with osteosarcoma treated with high-dose methotrexate based on individual pharmacokinetics: A retrospective study., Nagamine Ayumu;Araki Takuya;Yashima Hideaki;Kamimura Akane;Shiraishi Takumi;Yanagawa Takashi;Obayashi Kyoko;Yamamoto Koujirou, Dec. 2022, Oncology letters, 25, 2
    DOI
  • Risk of exposure of patients' family members to lenalidomide at home., Takahashi Yuta;Nagamine Ayumu;Kaneta Akiko;Yashima Hideaki;Obayashi Kyoko;Araki Takuya;Yamamoto Koujirou, Oct. 2024, European journal of hospital pharmacy : science and practice, 31, 6
    DOI
  • Blood Concentration of Cabazitaxel in a Patient Whose General Condition Worsened with Concomitant Use of Clarithromycin., Katsumi Shigeaki;Araki Takuya;Yashima Hideaki;Miyazawa Yoshiyuki;Suzuki Kazuhiro;Yamamoto Koujirou, Jul. 2023, Case reports in oncology, 16, 1
    DOI
  • Increased c‑SRC expression is involved in acquired resistance to lenvatinib in hepatocellular carcinoma., Takahashi Masamitsu;Araki Takuya;Yashima Hideaki;Nagamine Ayumu;Nagano Daisuke;Yamamoto Koujirou, Oct. 2023, Oncology letters, 26, 6
    DOI
  • 急性期病院における入院患者の転倒イベントと睡眠薬服用の関係, ;;;;, May 2023, 6回, 63
  • パニツムマブによる低マグネシウム血症の発症に及ぼす併用薬の影響, ;;;;;;, May 2024, 36, 306
  • 【ルーチン検査を薬物治療にどう活かす?気になる異常値&異常所見】異常値・異常所見へのアプローチはどうする?　全身状態, 八島 秀明, Aug. 2024, 66, 11, 2148
  • カルバペネム系抗菌薬の供給制限に伴う抗菌化学療法介入の影響, ;;;;;, May 2024, 98回・72回, np325
  • フェンタニル経皮吸収型製剤525μg/hを125μg/hまで減量しえた一例, ;;;;;, Jun. 2024, 19, Suppl., S.362
  • メトロニダゾール錠服用患者における脳症発生状況の調査, ;;;;, Jan. 2025, 73, 1, 67
  • 悪性脳腫瘍に対するATR-CHK1阻害による化学/放射線増感療法, ;;;;;;;, Aug. 2024, 74, 3, 244
  • Prediction and structural equation model of sertraline treatment response in Japanese patients with major depressive disorder., Nishioka Gentaro;Yashima Hideaki;Kiuchi Yuji;Nakamura Sumiko;Oyamada Hideto;Ishii Masakazu;Kudo Ikuo, Oct. 2013, Human psychopharmacology, 28, 6
    DOI
  • Patient resuscitated after cardiopulmonary arrest exhibits abnormally increased phenytoin metabolic rate due to unknown factors: a case report., Nagamine Ayumu;Araki Takuya;Yashima Hideaki;Oshima Kiyohiro;Obayashi Kyoko;Yamamoto Koujirou, Aug. 2024, Journal of pharmaceutical health care and sciences, 10, 1
    DOI
  • Therapeutic drug monitoring of docetaxel administered for breast cancer in a patient receiving rifampicin and clarithromycin to treat nontuberculous mycobacteriosis: A case report., Yashima Hideaki;Araki Takuya;Ishikawa Yuya;Ohshima Sohei;Nagano Daisuke;Obayashi Kyoko;Horiguchi Jun;Yamamoto Koujirou, Nov. 2024, Molecular and clinical oncology, 22, 2
    DOI
  • Variations in serum concentrations of sunitinib and its metabolites in patients receiving long-term sunitinib treatment., Sato Miki Takenaka;Araki Takuya;Yashima Hideaki;Ishikawa Yuya;Morita Jun;Maeda Yoshiko;Ohbayashi Masayuki;Kohyama Noriko;Ogawa Yoshio;Fukagai Takashi;Yamamoto Koujirou;Kogo Mari, Dec. 2024, Cancer chemotherapy and pharmacology, 95, 1
    DOI
  • Effect of dasatinib on blood concentrations of sunitinib and adverse events in a patient with metastatic renal cell carcinoma treated with sunitinib: A case report., Sato Miki Takenaka;Yashima Hideaki;Araki Takuya;Nomura Masashi;Suzuki Kazuhiro;Yamamoto Koujirou, Feb. 2025, Experimental and therapeutic medicine, 29, 4
    DOI

MISC

  • Prognostic potential of the MDM2 309T > G polymorphism in stage I lung adenocarcinoma, Yasuaki Enokida,Kimihiro Shimizu,Jun Atsumi,Seiichi Kakegawa,Yoshiaki Takase,Kyoichi Kaira,Hideaki Yashima,Takuya Araki,Seshiru Nakazawa,Yoichi Ohtaki,Toshiteru Nagashima,Lezhava Alexander,Kengo Usui,Toshihisa Ishikawa,Yoshihide Hayashizaki,Izumi Takeyoshi, Aug. 2016, CANCER MEDICINE, 5, 8, 1791, 1801
    DOI
  • Prognostic potential of the MDM2 309T > G polymorphism in stage I lung adenocarcinoma, Yasuaki Enokida,Kimihiro Shimizu,Jun Atsumi,Seiichi Kakegawa,Yoshiaki Takase,Kyoichi Kaira,Hideaki Yashima,Takuya Araki,Seshiru Nakazawa,Yoichi Ohtaki,Toshiteru Nagashima,Lezhava Alexander,Kengo Usui,Toshihisa Ishikawa,Yoshihide Hayashizaki,Izumi Takeyoshi, Aug. 2016, CANCER MEDICINE, 5, 8, 1791, 1801
    DOI
  • Prediction and structural equation model of sertraline treatment response in Japanese patients with major depressive disorder, Nishioka\, Gentaro,Yashima\, Hideaki,Kiuchi\, Yuji,Nakamura\, Sumiko,Oyamada\, Hideto,Ishii\, Masakazu,Kudo\, Ikuo, 2013, HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 28, 6, 576, 585
    DOI
  • Assessment of DDR2, BRAF, EGFR and KRAS mutations as therapeutic targets in non-adenocarcinoma lung cancer patients, Hideaki Yashima,Kimihiro Shimizu,Takuya Araki,Tohru Aomori,Yoichi Ohtaki,Toshiteru Nagashima,Yasuaki Enokida,Jun Atsumi,Tomonori Nakamura,Izumi Takeyoshi,Koujirou Yamamoto, 2014, Molecular and Clinical Oncology, 2, 5, 714, 718
    DOI
  • Review of the treatment of non-small cell lung cancer with gefitinib., Araki T,Yashima H,Shimizu K, 2012, lin Med Insights Oncol., 6, 407
    DOI
  • Prediction and structural equation model of sertraline treatment response in Japanese patients with major depressive disorder, Nishioka\, Gentaro,Yashima\, Hideaki,Kiuchi\, Yuji,Nakamura\, Sumiko,Oyamada\, Hideto,Ishii\, Masakazu,Kudo\, Ikuo, 2013, 28, 6, 576, 585
    DOI
  • Assessment of DDR2, BRAF, EGFR and KRAS mutations as therapeutic targets in non-adenocarcinoma lung cancer patients, Hideaki Yashima,Kimihiro Shimizu,Takuya Araki,Tohru Aomori,Yoichi Ohtaki,Toshiteru Nagashima,Yasuaki Enokida,Jun Atsumi,Tomonori Nakamura,Izumi Takeyoshi,Koujirou Yamamoto, 2014, 2, 5, 714, 718
    DOI
  • Review of the treatment of non-small cell lung cancer with gefitinib., Araki T,Yashima H,Shimizu K, 2012, 6, 407
    DOI

Presentations

  • Genetic variation of discoidin domain receptor 2, BRAF, EGFR and KRAS in Japanese non-adenocarcinoma lung cancer., Asian Federation of Pharmaceutical Society Meeting 2013., 2013
  • Development of a rapid evaluation method for therapeutic efficacy of antibiotics using quantification of bacterial ribosomal RNA precursors., 第8回次世代を担う若手医療薬科学シンポジウム, 2014
  • Genetic variation of discoidin domain receptor 2, BRAF, EGFR and KRAS in Japanese non-adenocarcinoma lung cancer., Asian Federation of Pharmaceutical Society Meeting 2013., 2013

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