Researcher Profile and Settings

Researcher

• Name

  Roppongi Reiko

Affiliation

• Pharmacology, Assistant Professor

Profile and Settings

• Name

  Reiko, Roppongi T

Alternate Names

• Reiko T. Roppongi
• Roppongi RT
• R T Roppongi
• 六本木(竹田)麗子

Affiliation

• Gunma University

Affiliation

• Affiliation

  Initiative for Advcance Research

Research Activities

Research Areas

• Life sciences, Neuroscience - general

Published Papers

• Easy and Reproducible Low-Density Primary Culture using Frozen Stock of Embryonic Hippocampal Neurons, Noriko Koganezawa, Reiko T Roppongi, Yuko Sekino, Izuo Tsutsui, Ayaka Higa, Tomoaki Shirao, 27 Jan. 2023, Journal of visualized experiments, 191

  DOI
• LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ. , Reiko T Roppongi, Shreya H Dhume, Nirmala Padmanabhan, Prabhisha Silwal, Nazmeena Zahra, Benyamin Karimi, Claire Bomkamp, Chetan S Patil, Kevin Champagne-Jorgensen, Rebecca E Twilley, Peng Zhang, Mich, 08 Apr. 2020, Neuron, 106, 1, 108, 125
• Low-Density Primary Hippocampal Neuron Culture., Reiko T Roppongi; Kevin P Champagne-Jorgensen; Tabrez J Siddiqui, 18 Apr. 2017, Journal of visualized experiments : JoVE, 122, Scientific journal

  DOI
• Role of LRRTMs in synapse development and plasticity., Reiko T Roppongi; Benyamin Karimi; Tabrez J Siddiqui, Mar. 2017, Neuroscience research, 116, 18, 28, Scientific journal

  DOI
• Early-stage development of human induced pluripotent stem cell-derived neurons., Yuki Ohara; Noriko Koganezawa; Hiroyuki Yamazaki; Reiko T Roppongi; Kaoru Sato; Yuko Sekino; Tomoaki Shirao, Dec. 2015, Journal of neuroscience research, 93, 12, 1804, 13, Scientific journal

  DOI
• Spikar, a novel drebrin-binding protein, regulates the formation and stabilization of dendritic spines., Hiroyuki Yamazaki; Nobuhiko Kojima; Kenichi Kato; Eiji Hirose; Toshiharu Iwasaki; Toshiyuki Mizui; Hideto Takahashi; Kenji Hanamura; Reiko T Roppongi; Noriyuki Koibuchi; Yuko Sekino; Nozomu Mori; Tomoaki Shirao, Feb. 2014, Journal of neurochemistry, 128, 4, 507, 22, Scientific journal

  DOI
• Selective reduction of drebrin and actin in dendritic spines of hippocampal neurons by activation of 5-HT(2A) receptors., Reiko T Roppongi; Nobuhiko Kojima; Kenji Hanamura; Hiroyuki Yamazaki; Tomoaki Shirao, 28 Jun. 2013, Neuroscience letters, 547, 76, 81, Scientific journal

  DOI
• Low accumulation of drebrin at glutamatergic postsynaptic sites on GABAergic neurons., K Hanamura; T Mizui; T Kakizaki; R T Roppongi; H Yamazaki; Y Yanagawa; T Shirao, 15 Sep. 2010, Neuroscience, 169, 4, 1489, 500, Scientific journal

  DOI
• Regulation of a synaptic pathway in Autism spectrum disorders, Roppongi Reiko T.;Siddiqui Tabrez J.;Dhume Shreya;Padmanabhan Nirmala;Silwal Prabhisha;Zahra Nazmeena;Patil Chetan;Champagne-Jorgensen Kevin;Jackson Michael F.;Shirao Tomoaki, 2020, Proceedings for Annual Meeting of The Japanese Pharmacological Society, 93, 0, 1, P-001
• High-throughput immunocytochemical assay to detect adverse effects of substances using cultured hippocampal neurons, Kenji Hanamura;Puspitasari Anggraeini;Roppongi Reiko;Yamamura Mai;Sekino Yuko;Shirao Tomoaki, 2020, Proceedings for Annual Meeting of The Japanese Pharmacological Society, 93, 0, 3, P-380
• Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits., Shreya H Dhume; Steven A Connor; Fergil Mills; Parisa Karimi Tari; Sarah H M Au-Yeung; Benjamin Karimi; Shinichiro Oku; Reiko T Roppongi; Hiroshi Kawabe; Shernaz X Bamji; Yu Tian Wang; Nils Brose; Michael F Jackson; Ann Marie Craig; Tabrez J Siddiqui, 06 Jun. 2022, eLife, 11, Scientific journal

  DOI
• Single-nucleus RNA sequencing reveals the shared mechanisms inducing cognitive impairment between COVID-19 and Alzheimer's disease., Yifan Fu; Zhirong Guo; Yulin Wang; Haonan Zhang; Feifan Zhang; Zihao Xu; Xin Shen; Reiko T Roppongi; Shaocong Mo; Wenchao Gu; Takahito Nakajima; Yoshito Tsushima, 2022, Frontiers in immunology, 13, 967356, 967356, Scientific journal

  DOI
• LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ., Reiko T Roppongi; Shreya H Dhume; Nirmala Padmanabhan; Prabhisha Silwal; Nazmeena Zahra; Benyamin Karimi; Claire Bomkamp; Chetan S Patil; Kevin Champagne-Jorgensen; Rebecca E Twilley; Peng Zhang; Michael F Jackson; Tabrez J Siddiqui, 20 May 2020, Neuron, 106, 4, 701, 701, Scientific journal

  DOI
• LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ., Reiko T Roppongi; Shreya H Dhume; Nirmala Padmanabhan; Prabhisha Silwal; Nazmeena Zahra; Benyamin Karimi; Claire Bomkamp; Chetan S Patil; Kevin Champagne-Jorgensen; Rebecca E Twilley; Peng Zhang; Michael F Jackson; Tabrez J Siddiqui, 08 Apr. 2020, Neuron, 106, 1, 108, 125, Scientific journal

  DOI
• Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits., Dhume Shreya H;Connor Steven A;Mills Fergil;Tari Parisa Karimi;Au-Yeung Sarah H M;Karimi Benjamin;Oku Shinichiro;Roppongi Reiko T;Kawabe Hiroshi;Bamji Shernaz X;Wang Yu Tian;Brose Nils;Jackson Michael F;Craig Ann Marie;Siddiqui Tabrez J, 06 Jun. 2022, eLife, 11

  DOI
• Single-nucleus RNA sequencing reveals the shared mechanisms inducing cognitive impairment between COVID-19 and Alzheimer's disease., Fu Yifan;Guo Zhirong;Wang Yulin;Zhang Haonan;Zhang Feifan;Xu Zihao;Shen Xin;Roppongi Reiko T;Mo Shaocong;Gu Wenchao;Nakajima Takahito;Tsushima Yoshito, 23 Sep. 2022, Frontiers in immunology, 13

  DOI
• Easy and Reproducible Low-Density Primary Culture using Frozen Stock of Embryonic Hippocampal Neurons., Noriko Koganezawa; Reiko T Roppongi; Yuko Sekino; Izuo Tsutsui; Ayaka Higa; Tomoaki Shirao, 27 Jan. 2023, Journal of visualized experiments : JoVE, 191, Scientific journal

  DOI
• ATR signaling controls the bystander responses of human chondrosarcoma cells by promoting RAD51-dependent DNA repair, Nho Cong Luong; Hidemasa Kawamura; Hiroko Ikeda; Reiko T. Roppongi; Atsushi Shibata; Jiaxuan Hu; Jinmeng G. Jiang; David S. Yu; Kathryn D. Held, 05 Mar. 2024, International Journal of Radiation Biology, 100, 5, 724, 735, Scientific journal

  DOI

MISC

• Effects of valproic acid and astemizole on the neurite growth of human iPSCs-derived neurons, Yuko Sekino; Mao Ootsu; Yuki Ohara; Hiroyuki Yamazaki; Kaoru Sato; Reiko T. Roppongi; Noriko Koganezawa; Tomoaki Shirao, Sep. 2015, JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 75, 200, 200, Summary international conference

  DOI
• Inhibitory effect of 5-HT2A receptor activity on drebrin accumulation in dendritic spines, Reiko T. Roppongi; Kenji Haramura; Tomoaki Shirao, 2010, NEUROSCIENCE RESEARCH, 68, E232, E232, Summary international conference

  DOI
• ヒトiPS分化細胞を利用した医薬品のヒト特異的有害反応評価系の開発・標準化 分化神経細胞に対する心臓リスク化合物の影響, 白尾智明; 大津真生; 山崎博幸; 小金澤紀子; 六本木麗子, 2015
• 5-HT2A受容体の活性化による樹状突起スパイン内ドレブリンの集積抑制効果(Inhibitory effect of 5-HT2A receptor activity on drebrin accumulation in dendritic spines), 六本木 麗子; 花村 健次; 白尾 智明, Aug. 2010, 神経化学, 49, 2-3, 611, 611
• 5-HT_2A受容体の活性化によるアクチン細胞骨格の変化, 六本木(竹田)麗子; 白尾智明, 2010, 60, 3, 301, 301
• Slow axonal growth of human iPSCs-derived neurons, N. Koganezawa; Y. Ohara; H. Yamazaki; R. T. Roppongi; K. Sato; Y. Sekino; T. Shirao, Aug. 2015, JOURNAL OF NEUROCHEMISTRY, 134, 311, 311, Summary international conference

Presentations

• High-throughput screening method using frozen neurons, Reiko T. Roppongi, 第100回生理学会, 16 Mar. 2023, 14 Mar. 2023, 16 Mar. 2023, English
• Effect of carbon-ion irradiation on immature hippocampal neurons, Reiko Roppongi, ISRN2022, 19 Mar. 2022, 19 Mar. 2022, 19 Mar. 2022
• Role of ATR signaling in the response of human chondrosarcoma cells to radiation -induced bystander effects, Reiko Roppongi, RRS2021, 03 Oct. 2021, 03 Oct. 2021, 06 Oct. 2021
• The synaptic organization LRRTM4-HS-Neurexin complex, Roppongi RT, 長崎大学　薬理学セミナー, 15 Jan. 2021
• Effect of carbon-ion irradiation on hippocampal neurons, Roppongi RT, Radiation Research Society 2020, 24 Oct. 2020, 28 Oct. 2020, English
• LRRTM4-HS-Neurexin complex is essensial for synapse development and function, Roppongi RT, 第43回日本神経科学大会, 31 Jul. 2020, 29 Jul. 2020, 01 Aug. 2020, English
• Carbon-ion irradiation causes immature neuron loss, altered levels of synaptic proteins and DNA damage., Roppongi RT; Kosasih DM; Hilfi L; Luong NC; Held KD, 17th ICRR, 27 Aug. 2023, 27 Aug. 2023, 30 Aug. 2023
• High-throughput screening method using frozen neurons, Reiko T. Roppongi, 第100回生理学会, 16 Mar. 2023, 14 Mar. 2023, 16 Mar. 2023, English

Research Projects

• 01 Apr. 2020, 31 Mar. 2022, 20K16690

  対象リソースIRI
• 29 Aug. 2014, 31 Mar. 2016, 26890006

  対象リソースIRI
• Development of microglia-targeting AAV vectors and its application to neurodegenerative disorders, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Gunma University, 01 Apr. 2023, 31 Mar. 2026, 23H02791

  対象リソースIRI