Laboratory Science, Professor

Saio M

M Saio

Gunma University, Professor

Gunma University, Professor

Life sciences, Human pathology

Pathology

Computer-assisted pathological image analysis

Cytopathology

Skewing the Th cell phenotype toward Th1 alters the maturation of tumor-infiltrating mononuclear phagocytes., Kenichi Nonaka; Masanao Saio; Tatsuhiko Suwa; Alan B Frey; Naoki Umemura; Hisashi Imai; Guan-Feng Ouyang; Shinji Osada; Margit Balazs; Roza Adany; Yoshihiro Kawaguchi; Kazuhiro Yoshida; Tsuyoshi Takami, Sep. 2008, Journal of leukocyte biology, 84, 3, 679, 88, Scientific journal

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics., Naoki Umemura; Masanao Saio; Tatsuhiko Suwa; Yusuke Kitoh; Juncheng Bai; Kenichi Nonaka; Guan-Feng Ouyang; Makoto Okada; Margit Balazs; Roza Adany; Toshiyuki Shibata; Tsuyoshi Takami, May 2008, Journal of leukocyte biology, 83, 5, 1136, 44, Scientific journal

Development of integrated backscatter intravascular ultrasound for tissue characterization of coronary plaques., Munenori Okubo; Masanori Kawasaki; Yoshiyuki Ishihara; Urara Takeyama; Tomoki Kubota; Takahiko Yamaki; Shinsuke Ojio; Kazuhiko Nishigaki; Genzou Takemura; Masanao Saio; Tsuyoshi Takami; Shinya Minatoguchi; Hisayoshi Fujiwara, Apr. 2008, Ultrasound in medicine & biology, 34, 4, 655, 63, Scientific journal

Metallothionein-3 is expressed in the brain and various peripheral organs of the rat., Isao Hozumi; Junko S Suzuki; Hiroaki Kanazawa; Akira Hara; Masanao Saio; Takashi Inuzuka; Shinichi Miyairi; Akira Naganuma; Chiharu Tohyama, 13 Jun. 2008, Neuroscience letters, 438, 1, 54, 8, Scientific journal

Critical role of CD44 in hepatotoxin-mediated liver injury., Kiminori Kimura; Masahito Nagaki; Kazuhiro Kakimi; Masanao Saio; Tomomi Saeki; Yumiko Okuda; Kazuo Kuwata; Hisataka Moriwaki, Jun. 2008, Journal of hepatology, 48, 6, 952, 61, Scientific journal

An Autopsy Case of Two Distinct, Acquired Drug Resistance Mechanisms in Epidermal Growth Factor Receptor-mutant Lung Adenocarcinoma: Small Cell Carcinoma Transformation and Epidermal Growth Factor Receptor T790M Mutation., Makoto Furugen; Kayoko Uechi; Jun Hirai; Hajime Aoyama; Masanao Saio; Naoki Yoshimi; Takeshi Kinjo; Kazuya Miyagi; Shusaku Haranaga; Futoshi Higa; Masao Tateyama; Jiro Fujita, 2015, Internal medicine (Tokyo, Japan), 54, 19, 2491, 6, Scientific journal

Role of CD44 in CTL-induced acute liver injury in hepatitis B virus transgenic mice., Kiminori Kimura; Masahito Nagaki; Masanao Saio; Hisataka Moriwaki; Kazuhiro Kakimi, 2009, Journal of gastroenterology, 44, 3, 218, 27, Scientific journal

Tumor-associated macrophage/microglia infiltration in human gliomas is correlated with MCP-3, but not MCP-1., Makoto Okada; Masanao Saio; Yusuke Kito; Naoyuki Ohe; Hirohito Yano; Shinichi Yoshimura; Toru Iwama; Tsuyoshi Takami, Jun. 2009, International journal of oncology, 34, 6, 1621, 7, Scientific journal

Dolichoectatic vertebrobasilar dissecting aneurysm originating from atherosclerosis: an autopsy case., Katsunori Isa; Hirokuni Sakima; Noritake Kosuge; Kazuhito Kokuba; Yoshino Goya; Koh Nakachi; Satoshi Ishihara; Takashi Tokashiki; Yusuke Ohya; Masanao Saio, 2013, Internal medicine (Tokyo, Japan), 52, 16, 1821, 3, Scientific journal

TGF-beta superfamily enhances the antigen-induced IFN-gamma production by effector/memory CD8+ T cells., Shinji Takai; Haruhiko Tokuda; Rie Matsushima-Nishiwaki; Masanao Saio; Tsuyoshi Takami; Osamu Kozawa, Jan. 2010, International journal of molecular medicine, 25, 1, 105, 11, Scientific journal

Tissue characterization of coronary plaques and assessment of thickness of fibrous cap using integrated backscatter intravascular ultrasound. Comparison with histology and optical coherence tomography., Masanori Kawasaki; Arihiro Hattori; Yoshiyuki Ishihara; Munenori Okubo; Kazuhiko Nishigaki; Genzou Takemura; Masanao Saio; Tsuyoshi Takami; Shinya Minatoguchi, Nov. 2010, Circulation journal : official journal of the Japanese Circulation Society, 74, 12, 2641, 8, Scientific journal

Suppression of right ventricular hypertrophy after extensive pulmonary resection in rats by granulocyte colony-stimulating factor., Shinsuke Matsumoto; Hisashi Iwata; Koyo Shirahashi; Masanao Saio; Yukio Umeda; Tsutomu Marui; Narihiro Ishida; Masaki Kimura; Takuya Sugimoto; Hideaki Manabe; Hirofumi Takemura, Aug. 2010, The Journal of surgical research, 162, 2, 153, 9, Scientific journal

Expression of vascular endothelial growth factor receptors is closely related to the histological grade of hepatocellular carcinoma., Nozomi Amaoka; Masanao Saio; Kenichi Nonaka; Hisashi Imai; Hiroyuki Tomita; Fumio Sakashita; Takao Takahashi; Yasuyuki Sugiyama; Tsuyoshi Takami; Yosuke Adachi, Jul. 2006, Oncology reports, 16, 1, 3, 10, Scientific journal

Interleukin-2 augmented activation of tumor associated macrophage plays the main role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro., Guan-Feng Ouyang; Masanao Saio; Tatsuhiko Suwa; Hisashi Imai; Jiro Nakagawa; Kenichi Nonaka; Naoki Umemura; Mika Kijima; Tsuyoshi Takami, May 2006, International journal of oncology, 28, 5, 1201, 8, Scientific journal

Preoperative radiotherapy contributes to induction of proliferative activity of CD8+ tumor-infiltrating T-cells in oral squamous cell carcinoma., Tatsuhiko Suwa; Masanao Saio; Naoki Umemura; Tomomi Yamashita; Makoto Toida; Toshiyuki Shibata; Tsuyoshi Takami, Apr. 2006, Oncology reports, 15, 4, 757, 63, Scientific journal

Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease., Kiminori Kimura; Hisataka Moriwaki; Masahito Nagaki; Masanao Saio; Yasunari Nakamoto; Makoto Naito; Kazuo Kuwata; Francis V Chisari, Mar. 2006, The American journal of pathology, 168, 3, 786, 95, Scientific journal

Fas and Fas ligand expression on germinal center type-diffuse large B-cell lymphoma is associated with the clinical outcome., Yasushi Kojima; Hisashi Tsurumi; Naoe Goto; Masahito Shimizu; Senji Kasahara; Toshiki Yamada; Nobuhiro Kanemura; Takeshi Hara; Michio Sawada; Masanao Saio; Tetsuya Yamada; Takeshi Takahashi; Eiichi Tomita; Tsuyoshi Takami; Hisataka Moriwaki, Jun. 2006, European journal of haematology, 76, 6, 465, 72, Scientific journal

Venous congestive myelopathy of the cervical spinal cord: an autopsy case showing a rapidly progressive clinical course., Akio Kimura; Chun-Feng Tan; Kenji Wakida; Masanao Saio; Isao Hozumi; Takashi Inuzuka; Hitoshi Takahashi, Jun. 2007, Neuropathology : official journal of the Japanese Society of Neuropathology, 27, 3, 284, 9, Scientific journal

TNF expressed by tumor-associated macrophages, but not microglia, can eliminate glioma., Jiro Nakagawa; Masanao Saio; Noriyuki Tamakawa; Tatsuhiko Suwa; Alan B Frey; Kenichi Nonaka; Naoki Umemura; Hisashi Imai; Guan-Feng Ouyang; Naoyuki Ohe; Hirohito Yano; Sinichi Yoshimura; Toru Iwama; Tsuyoshi Takami, Apr. 2007, International journal of oncology, 30, 4, 803, 11, Scientific journal

Depletion of CD4+CD25+ regulatory T cells enhances interleukin-2-induced antitumor immunity in a mouse model of colon adenocarcinoma., Hisashi Imai; Masanao Saio; Kenichi Nonaka; Tatsuhiko Suwa; Naoki Umemura; Guan-Feng Ouyang; Jiro Nakagawa; Hiroyuki Tomita; Shinji Osada; Yasuyuki Sugiyama; Yosuke Adachi; Tsuyoshi Takami, Mar. 2007, Cancer science, 98, 3, 416, 23, Scientific journal

Computer-aided diagnosis of hepatic fibrosis: preliminary evaluation of MRI texture analysis using the finite difference method and an artificial neural network., Hiroki Kato; Masayuki Kanematsu; Xuejun Zhang; Masanao Saio; Hiroshi Kondo; Satoshi Goshima; Hiroshi Fujita, Jul. 2007, AJR. American journal of roentgenology, 189, 1, 117, 22, Scientific journal

Natural killer cells play a role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro., Mika Kijima; Masanao Saio; Guan-Feng Oyang; Tatsuhiko Suwa; Rumiko Miyauchi; Yasushi Kojima; Hisashi Imai; Jiro Nakagawa; Kenichi Nonaka; Naoki Umemura; Takashi Nishimura; Tsuyoshi Takami, Mar. 2005, International journal of oncology, 26, 3, 679, 84, Scientific journal

Apoptosis induced by 5-fluorouracil, cisplatin and paclitaxel are associated with p53 gene status in gastric cancer cell lines., Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji, Jun. 2005, International journal of oncology, 26, 6, 1563, 7, Scientific journal

Expression of survivin and of antigen detected by a novel monoclonal antibody, T332, is associated with outcome of diffuse large B-cell lymphoma and its subtypes., Rumiko Watanuki-Miyauchi; Yasushi Kojima; Hisashi Tsurumi; Takeshi Hara; Naoe Goto; Seiji Kasahara; Masanao Saio; Hisataka Moriwaki; Tsuyoshi Takami, Jun. 2005, Pathology international, 55, 6, 324, 30, Scientific journal

The evaluation of gastric cancer sensitivity to 5-FU/CDDP in terms of induction of apoptosis: time- and p53 expression-dependency of anti-cancer drugs., Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji, Sep. 2005, Oncology reports, 14, 3, 609, 15, Scientific journal

The late recurrence of ganglioneuroma 21 years after initial presentation with neuroblastoma., Yoshiko Okita; Yoshitaka Narita; Akihiko Yoshida; Yasuji Miyakita; Makoto Ohno; Masanao Saio; Naoki Yoshimi; Soichiro Shibui, Oct. 2012, Pediatric hematology and oncology, 29, 7, 647, 51, Scientific journal

First trial of cervical cytology in healthy women of urban Laos using by self-sampling instrument., Viengvansay Nabandith; Vatsana Pholsena; Phouthasone Mounthisone; Kyoko Shimoe; Saiko Kato; Kunio Aoki; Sadamu Noda; Reika Takamatsu; Masanao Saio; Naoki Yoshimi, 2012, Asian Pacific journal of cancer prevention : APJCP, 13, 9, 4665, 7, Scientific journal

Lactobacillus acidophilus strain L-92 induces CD4(+)CD25(+)Foxp3(+) regulatory T cells and suppresses allergic contact dermatitis., Mohammad Monir Shah; Masanao Saio; Hirotaka Yamashita; Hiroyuki Tanaka; Tsuyoshi Takami; Takayuki Ezaki; Naoki Inagaki, 2012, Biological & pharmaceutical bulletin, 35, 4, 612, 6, Scientific journal

Pre-neoplastic lesion, mucin-depleted foci, reveals de novo high-grade dysplasia in rat colon carcinogenesis., Changxu Cui; Reika Takamatsu; Hiroshi Doguchi; Akiko Matsuzaki; Masanao Saio; Naoki Yoshimi, May 2012, Oncology reports, 27, 5, 1365, 70, Scientific journal

Failure of B7.1-modified tumor to evoke full activation of CD8+ tumor-infiltrating lymphocytes in the central nervous system: prevention of parental tumor growth in the subcutaneous environment., Hiromichi Ando; Masanao Saio; Noriyuki Tamakawa; Naoyuki Ohe; Takashi Nakayama; Hai Yu; Yasuhiko Kaku; Toru Iwama; Jun Shinoda; Noboru Sakai; Tsuyoshi Takami, Aug. 2002, Journal of neurosurgery, 97, 2, 432, 40, Scientific journal

B7.1 immunogene therapy effectively activates CD(4+) tumor-infiltrating lymphocytes in the central nervous system in comparison with B7.2 gene therapy., Hiromichi Ando; Masanao Saio; Naoyuki Ohe; Noriyuki Tamakawa; Hai Yu; Takashi Nakayama; Shin-ichi Yoshimura; Yasuhiko Kaku; Toru Iwama; Jun Shinoda; Noboru Sakai; Tsuyoshi Takami, Apr. 2002, International journal of oncology, 20, 4, 807, 12, Scientific journal

Specific CTL activity of CD8+ TCR Vbeta14+ T cell in mouse 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis., Toyoo Nitta; Hisashi Iwata; Yoshio Mori; Hisato Takagi; Toshio Hirota; Kazuto Kanetake; Yutaka Iida; Ken-Ichi Sakamoto; Takuya Yamada; Masanao Saio; Hajime Hirose, Oct. 2003, Digestive diseases and sciences, 48, 10, 2095, 103, Scientific journal

In situ detection of O6-methylguanine-DNA methyltransferase messenger RNA in paraffin-embedded human astrocytic tumor tissues by nested in situ RT-PCR is useful in predicting chemotherapy-resistance of tumors., Naoyuki Ohe; Masanao Saio; Mika Kijima; Noriyuki Tamakawa; Tatsuhiko Suwa; Yasushi Kojima; Hirohito Yano; Yasuhiko Kaku; Toru Iwama; Jun Shinoda; Noboru Sakai; Tsuyoshi Takami, Mar. 2003, International journal of oncology, 22, 3, 543, 9, Scientific journal

Interleukin-2 activated microglia engulf tumor infiltrating T cells in the central nervous system., Noriyuki Tamakawa; Masanao Saio; Tatsuhiko Suwa; Naoyuki Ohe; Shin-Ichi Yoshimura; Toru Iwama; Jun Shinoda; Noboru Sakai; Tsuyoshi Takami, Apr. 2004, International journal of molecular medicine, 13, 4, 497, 503, Scientific journal

Immunocytochemical demonstration of down regulation of HLA class-I molecule expression in human metastatic breast carcinoma., Masanao Saio; Matt Teicher; Gaynor Campbell; Helen Feiner; Yara Delgado; Alan B Frey, 2004, Clinical & experimental metastasis, 21, 3, 243, 9, Scientific journal

Biweekly CHOP or THP-COP regimens in the treatment of newly diagnosed aggressive non-Hodgkin's lymphoma. A comparison of doxorubicin and pirarubicin: a randomized phase II study., Hisashi Tsurumi; Toshiki Yamada; Michio Sawada; Senji Kasahara; Nobuhiro Kanemura; Yasushi Kojima; Kenji Fukuno; Takeshi Hara; Masanao Saio; Takeshi Takahashi; Masami Oyama; Keiya Ozawa; Tsuyoshi Takami; Hisataka Moriwaki, Feb. 2004, Journal of cancer research and clinical oncology, 130, 2, 107, 13, Scientific journal

p53 dependence and apoptosis in response to FP treatment with p53-transfected colon cancer cell lines by use of thin layer collagen gel., Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji, Aug. 2004, Oncology reports, 12, 2, 357, 61, Scientific journal

Translocation of lysophosphatidic acid phosphatase in response to gonadotropin-releasing hormone to the plasma membrane in ovarian cancer cell., Wen-Shu Sun; Atsushi Imai; Michiyo Sugiyama; Tatsuro Furui; Teruhiko Tamaya; Masanao Saio; Andrew J Morris, Jul. 2004, American journal of obstetrics and gynecology, 191, 1, 143, 9, Scientific journal

Expression of p53 protein as a predictor of the response to 5-fluorouracil and cisplatin chemotherapy in human gastrointestinal cancer cell lines evaluated with apoptosis by use of thin layer collagen gel., Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji, Apr. 2004, International journal of oncology, 24, 4, 807, 13, Scientific journal

Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase., Yoko Ono; Shinsuke Chiba; Hirohito Yano; Noriyuki Nakayama; Masanao Saio; Kazuhiro Tsuruma; Masamitsu Shimazawa; Toru Iwama; Hideaki Hara, 02 Dec. 2016, Biochemical and biophysical research communications, 481, 1-2, 7, 12, Scientific journal

Combined benign Brenner tumor and clear cell adenocarcinoma of the ovary., Hirofumi Matsumoto; Takaya Nakanishi; Hajime Aoyama; Masanao Saio; Wataru Kudaka; Yoichi Aoki; Shinichi Teshima; Seiya Kato, Jan. 2016, Pathology international, 66, 1, 47, 9

Combined GM-CSF treatment and M-CSF inhibition of tumor-associated macrophages induces dendritic cell-like signaling in vitro., Yusuke Kitoh; Masanao Saio; Naoe Gotoh; Naoki Umemura; Kenichi Nonaka; Juncheng Bai; Laura Vizkeleti; Daniel Torocsik; Margit Balazs; Roza Adany; Tsuyoshi Takami, May 2011, International journal of oncology, 38, 5, 1409, 19, Scientific journal

Plk1 is negatively regulated by RNF8., Takashi Yoshioka; Masashi Kimura; Masanao Saio; Seiichi Era; Yukio Okano, 24 Jun. 2011, Biochemical and biophysical research communications, 410, 1, 57, 61, Scientific journal

Nuclear features of infiltrating urothelial carcinoma are distinguished from low-grade noninvasive papillary urothelial carcinoma by image analysis., Noritake Kosuge; Masanao Saio; Hirofumi Matsumoto; Hajime Aoyama; Akiko Matsuzaki; Naoki Yoshimi, Sep. 2017, Oncology letters, 14, 3, 2715, 2722, Scientific journal

Kikuchi-Fujimoto disease in the regional lymph nodes with node metastasis in a patient with tongue cancer: A case report and literature review., Tessho Maruyama; Kazuhide Nishihara; Masanao Saio; Toshiyuki Nakasone; Fumikazu Nimura; Akira Matayoshi; Takahiro Goto; Naoki Yoshimi; Akira Arasaki, Jul. 2017, Oncology letters, 14, 1, 257, 263, Scientific journal

Recurrent female adnexal tumor of probable Wolffian origin treated with debulking surgery, imatinib and paclitaxel/carboplatin combination chemotherapy: A case report., Akihiko Wakayama; Hirofumi Matsumoto; Hajime Aoyama; Masanao Saio; Ayumi Kumagai; Takuma Ooyama; Morihiko Inamine; Yoichi Aoki, May 2017, Oncology letters, 13, 5, 3403, 3408, Scientific journal

Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial., Kiminori Kimura; Akemi Ikoma; Maki Shibakawa; Shinji Shimoda; Kenichi Harada; Masanao Saio; Jun Imamura; Yosuke Osawa; Masamichi Kimura; Koji Nishikawa; Takuji Okusaka; Satoshi Morita; Kazuaki Inoue; Tatsuya Kanto; Koji Todaka; Yoichi Nakanishi; Michinori Kohara; Masashi Mizokami, Sep. 2017, EBioMedicine, 23, 79, 87, Scientific journal

パラフィンブロック薄切時持続冷却の標本の厚みに与える影響の画像解析による検討, 齊尾 征直; 守谷 駿一; 藤森 美沙; 羽鳥 瑞歩; 小林 さやか; 木村 公則, May 2019, 69, 2, 97, 104

パラフィンブロック冷却装置付きミクロトームと義歯安定剤のブロック裏面隙間充填による連続薄切への効果の検討, 齊尾 征直; 羽鳥 瑞歩; 守谷 駿一; 小川 愛; 保戸山 央弓; 藤森 美沙; 農見 友梨; 小林 さやか; 木村 公則, Feb. 2019, 69, 1, 1, 6

Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma., Sayaka Kobayashi; Masanao Saio; Toshio Fukuda; Kiminori Kimura; Junko Hirato; Tetsunari Oyama, Jan. 2019, Oncology reports, 41, 1, 133, 142, Scientific journal

Mucoepidermoid Carcinoma of Arising from a Bronchogenic Cyst of the Diaphragm., Naohiro Taira; Hidenori Kawasaki; Eriko Atsumi; Takaharu Ichi; Tsutomu Kawabata; Masanao Saio; Naoki Yoshimi, 19 Oct. 2018, Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 24, 5, 247, 250, Scientific journal

Human papillomavirus genotyping among women with cervical abnormalities in Ulaanbaatar, Mongolia., Batchimeg Tsedenbal; Tomomi Yoshida; Bayarmaa Enkhbat; Uyanga Gotov; Enkhtuya Sharkhuu; Masanao Saio; Toshio Fukuda, Dec. 2018, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 77, 8, 13, Scientific journal

Triple primary malignancies of surface osteosarcoma of jaw, myelodysplastic syndrome and colorectal cancer as a second primary cancer detected by PET2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography: A case report., Nobuyuki Maruyama; Kazuhide Nishihara; Toshiyuki Nakasone; Masanao Saio; Tessho Maruyama; Iori Tedokon; Tetsuya Ohira; Fumikazu Nimura; Akira Matayoshi; Ken-Nosuke Karube; Naoki Yoshimi; Akira Arasaki, Jun. 2018, Oncology letters, 15, 6, 9901, 9907, Scientific journal

Giant pedunclated lipoma of the esophagus: A case report., Naohiro Taira; Hidenori Kawasaki; Akiko Koja; Tomonori Furugen; Yasuji Oshiro; Eriko Atsumi; Takaharu Ichi; Kazuaki Kushi; Tomofumi Yohena; Tsutomu Kawabata; Masanao Saio; Naoki Yoshimi, 2017, International journal of surgery case reports, 30, 55, 57, Scientific journal

Primary Villoglandular Mucinous Adenocarcinoma of the Vulva., Akiko Matsuzaki; Masanao Saio; Noritake Kosuge; Hajime Aoyama; Tomoko Tamaki; Hirofumi Matsumoto; Naoki Yoshimi, 2017, Case reports in pathology, 2017, 1765460, 1765460

Low-Grade Endometrial Stromal Sarcoma with Intravenous and Intracardiac Extension: A Multidisciplinary Approach., Wataru Kudaka; Hitoshi Inafuku; Yuko Iraha; Tomoko Nakamoto; Yusuke Taira; Rie Taira; Hisashi Kamiya; Maho Tsubakimoto; Yuichi Totsuka; Yukio Kuniyoshi; Tomoko Tamaki; Hajime Aoyama; Masanao Saio; Naoki Yoshimi; Yoichi Aoki, 2016, Case reports in obstetrics and gynecology, 2016, 3467849, 3467849, Scientific journal

Peritoneal Malignant Mesothelioma with Epithelioid Type, Demonstrating High Serum and Ascitic KL-6 Levels: Immunohistochemical Analyses., Saifun Nahar; Manabu Nakamoto; Akira Hokama; Chiharu Kobashigawa; Masatoshi Kaida; Tetsu Kinjo; Tetsuo Hirata; Nagisa Kinjo; Masanao Saio; Naoki Yoshimi; Yuji Ohtsuki; Jiro Fujita, 07 Sep. 2015, Rare tumors, 7, 3, 5947, 5947

The enhancing effects of hyperbaric oxygen on mouse skin carcinogenesis., Doguchi H; Saio M; Kuniyoshi S; Matsuzaki A; Yoshimi N, Apr. 2014, Journal of toxicologic pathology, 27, 1, 67, 72

[An autopsy case of hepatocellular carcinoma in which sarcoma-like changes and peritoneal dissemination were observed after RFA/TACE treatment]., Akihiro Obora; Takao Kojima; Takahiro Kato; Hideyuki Matsuda; Hideki Horie; Hiroaki Hashimoto; Nobuhiro Fukuta; Yukihiko Takano; Junichi Okuda; Kazunori Ida; Masanao Saio, Jul. 2009, Gan to kagaku ryoho. Cancer & chemotherapy, 36, 7, 1183, 6, Scientific journal

Tissue characterization of coronary plaques: comparison of integrated backscatter intravascular ultrasound with virtual histology intravascular ultrasound., Munenori Okubo; Masanori Kawasaki; Yoshiyuki Ishihara; Urara Takeyama; Shinji Yasuda; Tomoki Kubota; Shinichiro Tanaka; Takahiko Yamaki; Shinsuke Ojio; Kazuhiko Nishigaki; Genzou Takemura; Masanao Saio; Tsuyoshi Takami; Hisayoshi Fujiwara; Shinya Minatoguchi, Oct. 2008, Circulation journal : official journal of the Japanese Circulation Society, 72, 10, 1631, 9, Scientific journal

Advanced atherosclerotic plaque as a potential cause of no-reflow in elective percutaneous coronary intervention: intravascular ultrasound and histological findings., Shigenori Ito; Masanao Saio; Takahiko Suzuki, Nov. 2004, The Journal of invasive cardiology, 16, 11, 669, 72, Scientific journal

Radiological response and histological changes in malignant astrocytic tumors after stereotactic radiosurgery., Jun Shinoda; Hirohito Yano; Hiromichi Ando; Naoyuki Ohe; Noboru Sakai; Masanao Saio; Kuniyasu Shimokawa, 2002, Brain tumor pathology, 19, 2, 83, 92, Scientific journal

Metabolomic profiling of tumor-infiltrating macrophages during tumor growth., Naoki Umemura; Masahiro Sugimoto; Yusuke Kitoh; Masanao Saio; Hiroshi Sakagami, 09 Jun. 2020, Cancer immunology, immunotherapy : CII, Scientific journal

Temozolomide has anti-tumor effects through the phosphorylation of cPLA2 on glioblastoma cells., Shohei Tsuji; Yuta Ohno; Shinsuke Nakamura; Tetsuya Yamada; Yasuhiro Noda; Masanao Saio; Toru Iwama; Masamitsu Shimazawa; Hideaki Hara, 15 Nov. 2019, Brain research, 1723, 146396, 146396, Scientific journal

Hepatic Epithelioid Hemangioendothelioma: Vascular Penetration in the Tumor as a Characteristic Imaging FindingCase Report, Iraha R; Okada M; Kuniyoshi S; Arakaki S; Iraha T; Kinoshita R; Saio M; Yoshimi N; Iraha Y; Tanabe M; Numata K; Murayama S, 30 Aug. 2015, J Liver, 4, 184, 184, Scientific journal

CD8+ tumor-infiltrating lymphocytes are primed for fas-mediated activation-induced cell death but are not apoptotic in situ, Sasa Radoja; Masanao Saio; Alan B. Frey, 15 May 2001, Journal of Immunology, 166, 10, 6074, 6083, Scientific journal

Nuclear factor-κB activates dual inhibition sites in the regulation of tumor necrosis factor-α-induced neutrophil apoptosis, Masayuki Niwa; Akira Hara; Yutaka Kanamori; Daijiro Hatakeyama; Masanao Saio; Tsuyoshi Takami; Hiroyuki Matsuno; Osamu Kozawa; Toshihiko Uematsu, 03 Nov. 2000, European Journal of Pharmacology, 407, 3, 211, 219, Scientific journal

Role of rat adrenal antioxidant defense systems in the aldosterone turn-off phenomenon, Tetsuya Suwa; Tomoatsu Mune; Hiroyuki Morita; Hisashi Daido; Masanao Saio; Keigo Yasuda, 01 May 2000, Journal of Steroid Biochemistry and Molecular Biology, 73, 1-2, 71, 78, Scientific journal

Evidence for the synthesis of corticosteroid-binding globulin in human placenta, Ryou Misao; Shigenori Iwagaki; Wen-Shu Sun; Jiro Fujimoto; Masanao Saio; Tsuyoshi Takami; Teruhiko Tamaya, 1999, Hormone Research, 51, 4, 162, 167, Scientific journal

Increased levels of CSF soluble CD27 in patients with primary central nervous system lymphoma, Satoru Murase; Masanao Saio; Katsunobu Takenaka; Jun Shinoda; Yasuaki Nishimura; Noboru Sakai; Tsuyoshi Takami, 23 Oct. 1998, Cancer Letters, 132, 1-2, 181, 186, Scientific journal

A case of small hepatocellular carcinoma with intraabnominal lymph node metastasis after percutaneous ethanol injection therapy, Kiminori Kimura; Takahiro Uematsu; Naohiro Noda; Takafumi Naiki; Masanao Saio; Yasutosi Muto; Hisataka Moriwaki, 1998, Acta Hepatologica Japonica, 39, 3, 187, 192, Scientific journal

Macrophages in Giemsa-stained cerebrospinal fluid specimens predict carcinomatous meningitis, Kobayashi, S; Saio, M; Fujimori, M; Hirato, J; Oyama, T; Fukuda, T, Dec. 2020, Oncol Lett, 29, 6, 352, 352, Scientific journal

High neutrophil incorporation rate of ascitic fluid cytology as an indicator of cancerous ascites, Misa Fujimori; Haruyo Tsuchihashi; Shumpei Fujimori; Sayaka Kobayashi; Yuri Nomi; Junko Hirato; Tetsunari Oyama; Toshio Fukuda; Masanao Saio, Nov. 2020, International Journal of Oncology, 57, 5, 1214, 1222, Scientific journal

Phosphomolybdic Acid Prevents Nonspecific Nuclear Staining by Picrosirius Red but Is Converted to Molybdenum Blue by Blue Light, Mizuho Hatori; Shunichi Moriya; Misa Fujimori; Sayaka Kobayashi; Hayato Ikota; Ken Shirabe; Hideaki Yokoo; Kiminori Kimura; Masanao Saio, Sep. 2020, Journal of Histochemistry & Cytochemistry, 68, 9, 621, 634, Scientific journal

Possible mechanisms of action of clarithromycin and its clinical application as a repurposing drug for treating multiple myloma, Takemori, N; Ooi, HK; Imai, G; Hoshino, K; Saio, M, Aug. 2020, ecancermedicalscience, 14, 1, 24

若年者肺カルチノイドの2手術例, 嘉数 修; 大田 守雄; 當山 鉄男; 名嘉村 敬; 伊志嶺 朝彦; 玉城 和則; 國吉 真平; 青山 肇; 斉尾 征直, Nov. 2016, 肺癌, 56, 6, 725, 725

沖縄本島中部地区市町村子宮頸がん検診へのLBC全面導入効果 従来法とLBC法の比較検討, 黒島 義克; 大竹 賢太郎; 赤嶺 奈月; 青山 肇; 松崎 晶子; 齊尾 征直; 吉見 直己, May 2016, 55, 3, 137, 141

縦隔転移を機にTTF-1陽性小細胞癌の併存が確認された子宮体部類内膜腺癌の一例, 玉城 智子; モレロ,オースディン誠; 齊尾 征直; 國吉 真平; 小菅 則豪; 青山 肇; 松崎 晶子; 諸見里 秀彦; 太田 守雄; 吉見 直己, 2016, 33, 4, 306, 312

下顎骨に発生した原発性骨内扁平上皮癌の１例, 小山 寛文; 松崎 晶子; 林 昭伸; 齊尾 征直; 青山 肇; 吉見 直己, 2016, 33, 4, 313, 319

腫瘍核出術検体において部分肉腫化と診断したGnRH投与後の子宮平滑腫瘍の一例, 齊尾 征直; 小菅 則豪; 玉城 智子; 徳嶺 辰彦; 諸見里 秀彦; 吉見 直己, Nov. 2014, 5, 2, 65, 68

A2bとA6およびA3とA4+5が共通幹であった右上葉肺癌の1切除例, 嘉数 修; 大田 守雄; 當山 鉄男; 福里 夏海; 名嘉村 敬; 伊志嶺 朝彦; 玉城 和則; 國吉 真平; 青山 肇; 斉尾 征直, Oct. 2014, 肺癌, 54, 5, 368, 368

Mitotic catastrophe and cell death induced by depletion of centrosomal proteins, M Kimura; T Yoshioka; M Saio; Y Banno; H Nagaoka; Y Okano, Apr. 2013, Cell Death & Disease, 4, 4, e603, e603, Scientific journal

Growth Suppression and Mitotic Defect Induced by JNJ-7706621, an Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases, A. Matsuhashi; T. Ohno; M. Kimura; A. Hara; M. Saio; A. Nagano; G. Kawai; M. Saitou; I. Takigami; K. Yamada; Y. Okano; K. Shimizu, 01 May 2012, Current Cancer Drug Targets, 12, 6, 625, 639, Scientific journal

液状化検体細胞診(Liquid-Based Cytology;LBC)作製過程における粘液の影響, 黒島 義克; 大竹 賢太郎; 遠藤 理子; 齊尾 征直; 吉見 直己, May 2012, 51, 3, 220, 221

腎門部extra-adrenal myelolipomaの1例, 林 昭伸; 宮里 朝矩; 松崎 晶子; 小菅 則豪; 青山 肇; 齊尾 征直; 吉見 直己, Jul. 2011, 診断病理, 28, 3, 195, 197

涙腺の粘表皮癌の1例, 松崎 晶子; 川上 智子; 青山 肇; 林 昭伸; 齋尾 征直; 加治屋 志郎; 谷地森 隆二; 新濱 明彦; 澤口 昭一; 吉見 直己, Apr. 2011, 診断病理, 28, 2, 90, 93

A case of micronodular thymoma with lymphoid stroma, KITO Yusuke; HATANO Yuichirou; MATSUNAGA Kengo; HIROSE Yoshinobu; SAIO Masanao; MATSUMOTO Shinsuke; SHIRAHASHI Koyo; IWATA Hisashi; TAKAMI Tsuyoshi, Oct. 2008, 診断病理 : Japanese journal of diagnostic pathology, 25, 4, 267, 271

A Case of Hemangiosarcoma of the Spleen in which Supermass Chemotherapy was Successfully Performed, Kiyama Shigeru; Imai Naoki; Kasahara Senji; Takami Tuyoshi; Saio Masanao, 2007, The Japanese Journal of Gastroenterological Surgery, 40, 8, 1508, 1513

Si miao yong an tang induces a CD8+ T-cell mediated anti-B16 melanoma immune response, Yu, H; Saio, M, Mar. 2002, Acta Scholae Medicinalis Universitatis in Gifu, 50, 2, 46, 52, Research institution

剖検によりはじめて診断されたアミロイドーシスの2例, 中山 崇; 齊尾 征直; 于 海; 綿貫 ルミ子; 安藤 弘道; 大江 直行; 玉川 紀之; 高見 剛, Jan. 2002, 19, 1, 87, 90

Tumor-Infiltrating Macrophages Induce Apoptosis in Activated CD8+T Cells by a Mechanism Requiring Cell Contact and Mediated by Both the Cell-Associated Form of TNF and Nitric Oxide, Masanao Saio; Sasa Radoja; Mike Marino; Alan B. Frey, 15 Nov. 2001, The Journal of Immunology, 167, 10, 5583, 5593, Scientific journal

CD8+ Tumor-Infiltrating T Cells Are Deficient in Perforin-Mediated Cytolytic Activity Due to Defective Microtubule-Organizing Center Mobilization and Lytic Granule Exocytosis, Sasa Radoja; Masanao Saio; David Schaer; Mythili Koneru; Stanislav Vukmanovic; Alan B. Frey, 01 Nov. 2001, The Journal of Immunology, 167, 9, 5042, 5051, Scientific journal

Diagnostic utility of CSF soluble CD27 for primary central nervous system lymphoma in immunocompetent patients, Murase, S; Saio, M; Andoh, H; Takenaka, K; Shinoda, J; Nishimura, Y; Sakai, N; Takami, T, Jul. 2000, Neurol Res, 22, 5, 434, 424

Janus Effect of Local IFNg Administration in Tumor Immunotherapy, Saio, M, Jan. 1999, Acta Scholae Medicinalis Universitatis in Gifu, 47, 1, 1, 10, Research institution

全身性非定型抗酸菌症で死亡した後天性免疫不全症候群の1例, 齊尾 征直; 中山 崇; 田中 雄一; 山田 治; 奥野 正隆; 森脇 久隆; 高見 剛, May 1998, 15, 2, 98, 98

Endoscopic injection of gelatin solution for severe hemorrhagic gastric cancer, Tajika, M; Kato, T; Nagaki, M; Kato, M; Fukutomi, Y; Ninomiya, M; Moriwaki, H; Saio, M; Yamada, T; Takami, T; Muto, Y, Mar. 1996, Gastrointest Endosc, 43, 3, 247, 250, Scientific journal

Induction of M-CSF receptor and its mRNA, and activation of tyrosine kinase in peripheral monocytes by oestradiol-17 beta and progesterone, Fujimoto, J; Hori, M; Ichigo, S; Itoh, T; Saio, M; Takami, T; Tamaya, T, Jul. 1995, Ann Clin Biochem, 32, 399, 404, Scientific journal

Formation and growth of multicellular spheroids in media containing low concentrations of agarose, Kuwashima, Y; Yamada, T; Saio, M; Takami, T, Jul. 1993, Cancer Lett, 71, 1-3, 31, 33, Scientific journal

Growth characteristics of murine B16 melanoma multicellular spheroids: a model for invasion and effects of doxorubicin treatments, Kuwashima, Y; Yamada, T; Saio, M; Takami, T, Jul. 1993, Anticancer Res, 13, 4, 1215, 1217, Scientific journal

MicroRNA 182, 183, 200a, and 200b exhibit strong correlations but no involvement in PTEN protein regulation in uterine endometrial carcinoma., Yoshimi Nishijima; Naoki Inoue; Akira Iwase; Hideaki Yokoo; Masanao Saio, 17 Jun. 2022, Pathology, research and practice, 236, 153986, 153986, Scientific journal

Safety, tolerability, and anti-fibrotic efficacy of the CBP/β-catenin inhibitor PRI-724 in patients with hepatitis C and B virus-induced liver cirrhosis: An investigator-initiated, open-label, non-randomised, multicentre, phase 1/2a study, Kiminori Kimura; Tatsuya Kanto; Shinji Shimoda; Kenichi Harada; Masamichi Kimura; Koji Nishikawa; Jun Imamura; Eiichi Ogawa; Masanao Saio; Yoshihiro Ikura; Takuji Okusaka; Kazuaki Inoue; Tetsuya Ishikawa; Ichiro Ieiri; Junji Kishimoto; Koji Todaka; Terumi Kamisawa, Jun. 2022, eBioMedicine, 80, 104069, 104069, Scientific journal

Role of Lamin A and emerin in maintaining nuclear morphology in different subtypes of ovarian epithelial cancer., Shiori Watabe; Sayaka Kobayashi; Mizuho Hatori; Yoshimi Nishijima; Naoki Inoue; Hayato Ikota; Akira Iwase; Hideaki Yokoo; Masanao Saio, Jan. 2022, Oncology letters, 23, 1, 9, 9, Scientific journal

Th1 polarization in the tumor microenvironment upregulates the myeloid-derived suppressor-like function of macrophages., Kenichi Nonaka; Masanao Saio; Naoki Umemura; Arizumi Kikuchi; Takao Takahashi; Shinji Osada; Kazuhiro Yoshida, 07 Sep. 2021, Cellular immunology, 369, 104437, 104437, Scientific journal

Computer-assisted image analysis of cytological specimens clarify the correlation between nuclear size and intranuclear cytoplasmic inclusions regardless of BRAFV600E mutation in papillary thyroid carcinoma., Midori Suzuki; Shunichi Moriya; Sayaka Kobayashi; Yoshimi Nishijima; Takaaki Fujii; Hayato Ikota; Hideaki Yokoo; Masanao Saio, 22 Jun. 2021, Cytopathology : official journal of the British Society for Clinical Cytology, 32, 6, 718, 731, Scientific journal

Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma., Shohei Tsuji; Shinsuke Nakamura; Takashi Maoka; Tetsuya Yamada; Takahiko Imai; Takuya Ohba; Tomohiro Yako; Masahiro Hayashi; Ken Endo; Masanao Saio; Hideaki Hara; Masamitsu Shimazawa, 18 Sep. 2020, Marine drugs, 18, 9, Scientific journal

Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma, Shohei Tsuji; Shinsuke Nakamura; Takashi Maoka; Tetsuya Yamada; Takahiko Imai; Takuya Ohba; Tomohiro Yako; Masahiro Hayashi; Ken Endo; Masanao Saio; Hideaki Hara; Masamitsu Shimazawa, Sep. 2020, MARINE DRUGS, 18, 9, Scientific journal

肝細胞癌硬膜転移による硬膜下血腫 -臨床報告と文献的考察-, 田中優司; 河口順二; 林 秀樹; 植松孝広; 山田 潤; 岩間 亨; 齊尾征直; 森脇久隆, 2004, 26, 382, 386

Effect of lamins and emerin on nuclear morphology and histological architecture in lung adenocarcinoma., Sayaka Kobayashi; Yuki Kanehira; Raia Kushibiki; Yoshimi Nishijima; Toshiteru Nagashima; Yoichi Ohtaki; Hayato Ikota; Hideaki Yokoo; Masanao Saio, 24 Aug. 2024, Pathology, research and practice, 262, 155557, 155557, Scientific journal

Continuous specimen cooling during slicing and thickness measurement contributes to improved accuracy in image analysis of pathologic specimens., Masanao Saio; Raia Kushibiki; Yuki Kanehira; Akifumi Ishizawa; Yuka Abe; Sayaka Kobayashi; Yoshimi Nishijima, 19 Apr. 2024, Histology and histopathology, 18751, 18751, Scientific journal

Decreased lamin A and B1 expression results in nuclear enlargement in serous ovarian carcinoma, whereas lamin A-expressing tumor cells metastasize to lymph nodes, Miduki Ouchi; Sayaka Kobayashi; Yoshimi Nishijima; Naoki Inoue; Hayato Ikota; Akira Iwase; Hideaki Yokoo; Masanao Saio, May 2023, Pathology - Research and Practice, 154560, 154560, Scientific journal

Phosphotungstic Acid-treated Picrosirius Red Staining Improves Whole-slide Quantitative Analysis of Collagen in Histological Specimens., Yui Mukade; Sayaka Kobayashi; Yoshimi Nishijima; Kiminori Kimura; Akira Watanabe; Hayato Ikota; Ken Shirabe; Hideaki Yokoo; Masanao Saio, 26 Nov. 2022, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 221554221141140, 221554221141140, Scientific journal

Feasibility, safety and tolerability of the CREB-binding protein/β-catenin inhibitor OP-724 in patients with advanced primary biliary cholangitis: an investigator-initiated, open-label, non-randomised, two-centre, phase 1 study., Masamichi Kimura; Eiichi Ogawa; Kenichi Harada; Jun Imamura; Masanao Saio; Yoshihiro Ikura; Hiroshi Yatsuhashi; Kazumoto Murata; Kouichi Miura; Ichiro Ieiri; Atsushi Tanaka; Kiminori Kimura, Nov. 2022, BMJ open gastroenterology, 9, 1, Scientific journal

Negative correlation between the nuclear size and nuclear Lamina component Lamin A in intraductal papillary mucinous neoplasms of the pancreas., Tamaki Hiroe; Shunichi Moriya; Sayaka Kobayashi; Yoshimi Nishijima; Akira Watanabe; Ken Shirabe; Hayato Ikota; Hideaki Yokoo; Masanao Saio, 2022, Pathology oncology research : POR, 28, 1610684, 1610684, Scientific journal

Benign epithelial inclusion consisting of squamous metaplasia and small glandular elements in regional lymph node of a patient with tongue cancer: A case report and literature review, Tessho Maruyama; Toshiyuki Nakasone; Masanao Saio; Kazuhide Nishihara; Akira Matayoshi; Takahiro Goto; Naoki Yoshimi; Akira Arasaki, 2016, International Journal of Clinical and Experimental Pathology, 9, 3, 4027, 4032, Scientific journal

胸腔鏡下に切除した縦隔内甲状腺腫瘍の2例, 前田 晃宏; 大田 守雄; 嘉数 修; 當山 鉄男; 林 圭吾; 後藤 倫子; 馬場 徳朗; 小倉 加奈子; 上里 安範; 卸川 智文; 間山 泰晃; 兼城 達也; 砂川 宏樹; 座波 久光; 與那覇 俊美; 大城 直人; 上地 襄; 斉尾 征直, Dec. 2015, 54, 3, 119, 119

胎児型横紋筋肉腫成分を含む前縦隔混合性胚細胞腫瘍の1例, 熱海 恵理子; 古堅 智則; 照屋 孝夫; 平安 恒男; 饒平名 知史; 川畑 勉; 齊尾 征直; 加藤 誠也, Mar. 2014, 103, 1, 352, 352

不明熱の原因精査に骨髄生検が有用であったホジキンリンパ腫の1例, 森近 一穂; 仲地 佐和子; 友寄 毅昭; 西 由希子; 玉城 啓太; 城間 紀之; 齊尾 征直; 吉見 直己; 益崎 裕章, May 2013, 51, 4, 69, 71

Phosphomolybdic Acid Prevents Nonspecific Nuclear Staining by Picrosirius Red but Is Converted to Molybdenum Blue by Blue Light, Hatori, Mizuho;Moriya, Shunichi;Fujimori, Misa;Kobayashi, Sayaka;Ikota, Hayato;Shirabe, Ken;Yokoo, Hideaki;Kimura, Kiminori;Saio, Masanao, 2020, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 68, 9, 621, 634

Mucoepidermoid Carcinoma of Arising from a Bronchogenic Cyst of the Diaphragm, Taira Naohiro;Kawasaki Hidenori;Atsumi Eriko;Ichi Takaharu;Kawabata Tsutomu;Saio Masanao;Yoshimi Naoki, 2018, Annals of Thoracic and Cardiovascular Surgery, 24, 5, 247, 250

子宮頸部上皮内腫瘍(CIN)におけるRNAscopeISH法を用いたHPV E6/E7mRNA発現の検討, ;;;, Oct. 2017, 56, Suppl.2, 701

子宮頸部病変があるモンゴル人女性におけるヒトパピローマウイルス遺伝子型の検出(Human Papillomavirus genotypes detection in Mongolian women with cervical lesion), ;;;;, Oct. 2017, 56, Suppl.2, 704

保健学研究科の病理・細胞診分野における私の今後の教育と研究, 齊尾 征直, Aug. 2018, 68, 3, 189

Mucoepidermoid Carcinoma of Arising from a Bronchogenic Cyst of the Diaphragm, Taira, Naohiro;Kawasaki, Hidenori;Atsumi, Eriko;Ichi, Takaharu;Kawabata, Tsutomu;Saio, Masanao;Yoshimi, Naoki, 2018, ANNALS OF THORACIC AND CARDIOVASCULAR SURGERY, 24, 5, 247, 250

Human papillomavirus genotyping among women with cervical abnormalities in Ulaanbaatar, Mongolia, Tsedenbal, Batchimeg;Yoshida, Tomomi;Enkhbat, Bayarmaa;Gotov, Uyanga;Sharkhuu, Enkhtuya;Saio, Masanao;Fukuda, Toshio, 2018, INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 77, 8, 13

Temozolomide has anti-tumor effects through the phosphorylation of cPLA₂ on glioblastoma cells, Tsuji, Shohei;Ohno, Yuta;Nakamura, Shinsuke;Yamada, Tetsuya;Noda, Yasuhiro;Saio, Masanao;Iwama, Toru;Shimazawa, Masamitsu;Hara, Hideaki, 2019, BRAIN RESEARCH, 1723

High neutrophil incorporation rate of ascitic fluid cytology as an indicator of cancerous ascites, Fujimori, Misa;Tsuchihashi, Haruyo;Fujimori, Shumpei;Kobayashi, Sayaka;Nomi, Yuri;Hirato, Junko;Oyama, Tetsunari;Fukuda, Toshio;Saio, Masanao, 2020, INTERNATIONAL JOURNAL OF ONCOLOGY, 57, 5, 1214, 1222

Macrophages in Giemsa-stained cerebrospinal fluid specimens predict carcinomatous meningitis, Kobayashi, Sayaka;Saio, Masanao;Fujimori, Misa;Hirato, Junko;Oyama, Tetsunari;Fukuda, Toshio, 2020, ONCOLOGY LETTERS, 20, 6

MicroRNA 182, 183, 200a, and 200b exhibit strong correlations but no involvement in PTEN protein regulation in uterine endometrial carcinoma, Nishijima, Yoshimi;Inoue, Naoki;Iwase, Akira;Yokoo, Hideaki;Saio, Masanao, 2022, PATHOLOGY RESEARCH AND PRACTICE, 236

Denture Adhesive Used as Gap Filler when Using a Cooling System Installed Microtome: Effects on Preparation of Thin Serial Sections, Saio Masanao;Hatori Mizuho;Moriya Syunichi;Ogawa Mana;Hotoyama Hiroyu;Fujimori Misa;Nomi Yuri;Kobayashi Sayaka;Kimura Kiminori, Feb. 2019, The Kitakanto Medical Journal, 69, 1, 1, 6

パラフィンブロック冷却装置付きミクロトームと義歯安定剤のブロック裏面隙間充填による連続薄切への効果の検討, ;;;;;;;;, Feb. 2019, 69, 1, 1

Macrophages in Giemsa-stained cerebrospinal fluid specimens predict carcinomatous meningitis., Kobayashi Sayaka;Saio Masanao;Fujimori Misa;Hirato Junko;Oyama Tetsunari;Fukuda Toshio, Oct. 2020, Oncology letters, 20, 6

Decreased lamin A and B1 expression results in nuclear enlargement in serous ovarian carcinoma, whereas lamin A-expressing tumor cells metastasize to lymph nodes., Ouchi Miduki;Kobayashi Sayaka;Nishijima Yoshimi;Inoue Naoki;Ikota Hayato;Iwase Akira;Yokoo Hideaki;Saio Masanao, May 2023, Pathology, research and practice, 247

Negative correlation between the nuclear size and nuclear Lamina component Lamin A in intraductal papillary mucinous neoplasms of the pancreas, Hiroe, Tamaki;Moriya, Shunichi;Kobayashi, Sayaka;Nishijima, Yoshimi;Watanabe, Akira;Shirabe, Ken;Ikota, Hayato;Yokoo, Hideaki;Saio, Masanao, 2022, PATHOLOGY & ONCOLOGY RESEARCH, 28

パラフィンブロック薄切時持続冷却の標本の厚みに与える影響の画像解析による検討, ;;;;;, May 2019, 69, 2, 97

義歯安定剤とミクロトーム冷却装置を用いた連続薄切条件の検討, ;;;;;, Apr. 2019, 108, 1, 458

ミクロトーム冷却装置を用いた連続薄切の精度の検討, ;;;;;, Apr. 2019, 108, 1, 458

魚肉ソーセージ切片と画像解析を組み合わせた検量線作製の試み, ;;;;;;;, Aug. 2019, 69, 3, 294

滑走式と回転式ミクロトームにおける薄切時摩擦熱の検討, ;;;;, Aug. 2019, 69, 3, 297

滑走式ミクロトームの型の違いと標本薄切に与える影響について, ;;;;;;;, Aug. 2019, 69, 3, 305

BRAFV600E変異の有無と甲状腺乳頭癌の細胞学的特徴の検討, ;;;;;;, May 2021, 60, Suppl.1, 252

慢性期Chagas病マウスモデルの確立と病態変化の解析, ;;;;;;;, Apr. 2021, 90回・32回, 81

子宮頸部細胞診のASC-H判定と年齢との関係性の検討, ;;;, Oct. 2022, 61, Suppl.2, 479

細胞内細胞現象の捉え方と研究の動向, ;;;;;;;;;;, Oct. 2022, 61, Suppl.2, 541

Sirius Red染色におけるリンモリブデン酸前処理の非特異的染色性抑制効果の検討, ;;;, Oct. 2022, 111, 2, 102

卵巣漿液性腺癌原発巣におけるLaminA,LaminB1,LaminB2の卵管との発現比較, ;;;, Oct. 2022, 111, 2, 106

マウスモデルを用いた慢性期シャーガス病治療薬の探索, ;;;;, Aug. 2022, 72, 3, 321

ヒト肝組織のSirius Red染色におけるリンモリブデン酸前処理の非特異的染色性低減効果の検討, ;;;, Aug. 2022, 72, 3, 323

使用細胞数とセルブロック上の細胞数のコンピュータ支援画像解析による比較検討, ;;;;;, Oct. 2023, 62, Suppl.2, 501

培養細胞を用いた疑似試料による細胞接着性のコンピュータ支援画像解析による比較検討, ;;;;;, Oct. 2023, 62, Suppl.2, 502

Nuclear features of infiltrating urothelial carcinoma are distinguished from low-grade noninvasive papillary urothelial carcinoma by image analysis., Kosuge Noritake;Saio Masanao;Matsumoto Hirofumi;Aoyama Hajime;Matsuzaki Akiko;Yoshimi Naoki, Jun. 2017, Oncology letters, 14, 3

Mucoepidermoid Carcinoma of Arising from a Bronchogenic Cyst of the Diaphragm., Taira Naohiro;Kawasaki Hidenori;Atsumi Eriko;Ichi Takaharu;Kawabata Tsutomu;Saio Masanao;Yoshimi Naoki, Jan. 2018, Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 24, 5

Triple primary malignancies of surface osteosarcoma of jaw, myelodysplastic syndrome and colorectal cancer as a second primary cancer detected by PET2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography: A case report., Maruyama Nobuyuki;Nishihara Kazuhide;Nakasone Toshiyuki;Saio Masanao;Maruyama Tessho;Tedokon Iori;Ohira Tetsuya;Nimura Fumikazu;Matayoshi Akira;Karube Ken-Nosuke;Yoshimi Naoki;Arasaki Akira, Apr. 2018, Oncology letters, 15, 6

Human papillomavirus genotyping among women with cervical abnormalities in Ulaanbaatar, Mongolia., Tsedenbal Batchimeg;Yoshida Tomomi;Enkhbat Bayarmaa;Gotov Uyanga;Sharkhuu Enkhtuya;Saio Masanao;Fukuda Toshio, Sep. 2018, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 77

Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma., Kobayashi Sayaka;Saio Masanao;Fukuda Toshio;Kimura Kiminori;Hirato Junko;Oyama Tetsunari, Nov. 2018, Oncology reports, 41, 1

Temozolomide has anti-tumor effects through the phosphorylation of cPLA2 on glioblastoma cells., Tsuji Shohei;Ohno Yuta;Nakamura Shinsuke;Yamada Tetsuya;Noda Yasuhiro;Saio Masanao;Iwama Toru;Shimazawa Masamitsu;Hara Hideaki, Aug. 2019, Brain research, 1723

Metabolomic profiling of tumor-infiltrating macrophages during tumor growth., Umemura Naoki;Sugimoto Masahiro;Kitoh Yusuke;Saio Masanao;Sakagami Hiroshi, Jun. 2020, Cancer immunology, immunotherapy : CII, 69, 11

Phosphomolybdic Acid Prevents Nonspecific Nuclear Staining by Picrosirius Red but Is Converted to Molybdenum Blue by Blue Light., Hatori Mizuho;Moriya Shunichi;Fujimori Misa;Kobayashi Sayaka;Ikota Hayato;Shirabe Ken;Yokoo Hideaki;Kimura Kiminori;Saio Masanao, Jul. 2020, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 68, 9

High neutrophil incorporation rate of ascitic fluid cytology as an indicator of cancerous ascites., Fujimori Misa;Tsuchihashi Haruyo;Fujimori Shumpei;Kobayashi Sayaka;Nomi Yuri;Hirato Junko;Oyama Tetsunari;Fukuda Toshio;Saio Masanao, Sep. 2020, International journal of oncology, 57, 5

Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma., Tsuji Shohei;Nakamura Shinsuke;Maoka Takashi;Yamada Tetsuya;Imai Takahiko;Ohba Takuya;Yako Tomohiro;Hayashi Masahiro;Endo Ken;Saio Masanao;Hara Hideaki;Shimazawa Masamitsu, Sep. 2020, Marine drugs, 18, 9

Possible mechanisms of action of clarithromycin and its clinical application as a repurposing drug for treating multiple myeloma., Takemori Nobuo;Ooi Hong-Kean;Imai Goro;Hoshino Kazuo;Saio Masanao, Aug. 2020, Ecancermedicalscience, 14

Computer-assisted image analysis of cytological specimens clarify the correlation between nuclear size and intranuclear cytoplasmic inclusions regardless of BRAFV600E mutation in papillary thyroid carcinoma., Suzuki Midori;Moriya Shunichi;Kobayashi Sayaka;Nishijima Yoshimi;Fujii Takaaki;Ikota Hayato;Yokoo Hideaki;Saio Masanao, Jul. 2021, Cytopathology : official journal of the British Society for Clinical Cytology, 32, 6

Th1 polarization in the tumor microenvironment upregulates the myeloid-derived suppressor-like function of macrophages., Nonaka Kenichi;Saio Masanao;Umemura Naoki;Kikuchi Arizumi;Takahashi Takao;Osada Shinji;Yoshida Kazuhiro, Sep. 2021, Cellular immunology, 369

Role of Lamin A and emerin in maintaining nuclear morphology in different subtypes of ovarian epithelial cancer., Watabe Shiori;Kobayashi Sayaka;Hatori Mizuho;Nishijima Yoshimi;Inoue Naoki;Ikota Hayato;Iwase Akira;Yokoo Hideaki;Saio Masanao, Nov. 2021, Oncology letters, 23, 1

Safety, tolerability, and anti-fibrotic efficacy of the CBP/β-catenin inhibitor PRI-724 in patients with hepatitis C and B virus-induced liver cirrhosis: An investigator-initiated, open-label, non-randomised, multicentre, phase 1/2a study., Kimura Kiminori;Kanto Tatsuya;Shimoda Shinji;Harada Kenichi;Kimura Masamichi;Nishikawa Koji;Imamura Jun;Ogawa Eiichi;Saio Masanao;Ikura Yoshihiro;Okusaka Takuji;Inoue Kazuaki;Ishikawa Tetsuya;Ieiri Ichiro;Kishimoto Junji;Todaka Koji;Kamisawa Terumi, May 2022, EBioMedicine, 80

MicroRNA 182, 183, 200a, and 200b exhibit strong correlations but no involvement in PTEN protein regulation in uterine endometrial carcinoma., Nishijima Yoshimi;Inoue Naoki;Iwase Akira;Yokoo Hideaki;Saio Masanao, Jun. 2022, Pathology, research and practice, 236

Phosphotungstic Acid-treated Picrosirius Red Staining Improves Whole-slide Quantitative Analysis of Collagen in Histological Specimens., Mukade Yui;Kobayashi Sayaka;Nishijima Yoshimi;Kimura Kiminori;Watanabe Akira;Ikota Hayato;Shirabe Ken;Yokoo Hideaki;Saio Masanao, Nov. 2022, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 71, 1

Feasibility, safety and tolerability of the CREB-binding protein/β-catenin inhibitor OP-724 in patients with advanced primary biliary cholangitis: an investigator-initiated, open-label, non-randomised, two-centre, phase 1 study., Kimura Masamichi;Ogawa Eiichi;Harada Kenichi;Imamura Jun;Saio Masanao;Ikura Yoshihiro;Yatsuhashi Hiroshi;Murata Kazumoto;Miura Kouichi;Ieiri Ichiro;Tanaka Atsushi;Kimura Kiminori, BMJ open gastroenterology, 9, 1

Negative correlation between the nuclear size and nuclear Lamina component Lamin A in intraductal papillary mucinous neoplasms of the pancreas., Hiroe Tamaki;Moriya Shunichi;Kobayashi Sayaka;Nishijima Yoshimi;Watanabe Akira;Shirabe Ken;Ikota Hayato;Yokoo Hideaki;Saio Masanao, Dec. 2022, Pathology oncology research : POR, 28

Results of Self-Sampling Methodology Impression for Cervical Cancer Screening in Mongolia., Tsedenbal Batchimeg;Enebish Gerelmaa;Tserensodnom Bayasgalan;Saio Masanao, Dec. 2022, Asian Pacific journal of cancer prevention : APJCP, 23, 12

培養細胞を用いたセルブロック作製条件の検討, ;;;;;, Aug. 2023, 73, 3, 247

慢性期シャーガス病マウスモデルを用いたキノン含有化合物の抗原虫作用の検討, ;;;;;;, Aug. 2023, 73, 3, 257

使用細胞数とセルブロック上の細胞数のコンピュータ支援画像解析による比較検討, ;;;;;, Oct. 2023, 62, Suppl.2, 501

培養細胞を用いた疑似試料による細胞接着性のコンピュータ支援画像解析による比較検討, ;;;;;, Oct. 2023, 62, Suppl.2, 502

ヒト肺腺癌細胞株におけるドライバー遺伝子変異特異的microRNA発現の解析, ;;;;;;;, Feb. 2024, 74, 1, 43

培養細胞における細胞内細胞現象を用いた機械学習の精度とブラックボックス問題の検討, ;;;;;, Feb. 2024, 74, 1, 51

Nuclear features of infiltrating urothelial carcinoma are distinguished from low-grade noninvasive papillary urothelial carcinoma by image analysis, Kosuge, Noritake;Saio, Masanao;Matsumoto, Hirofumi;Aoyama, Hajime;Matsuzaki, Akiko;Yoshimi, Naoki, 2017, ONCOLOGY LETTERS, 14, 3, 2715, 2722

Triple primary malignancies of surface osteosarcoma of jaw, myelodysplastic syndrome and colorectal cancer as a second primary cancer detected by PET2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography: A case report, Maruyama, Nobuyuki;Nishihara, Kazuhide;Nakasone, Toshiyuki;Saio, Masanao;Maruyama, Tessho;Tedokon, Iori;Ohira, Tetsuya;Nimura, Fumikazu;Matayoshi, Akira;Karube, Ken-Nosuke;Yoshimi, Naoki;Arasaki, Akira, 2018, ONCOLOGY LETTERS, 15, 6, 9901, 9907

Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma, Kobayashi, Sayaka;Saio, Masanao;Fukuda, Toshio;Kimura, Kiminori;Hirato, Junko;Oyama, Tetsunari, 2019, ONCOLOGY REPORTS, 41, 1, 133, 142

Metabolomic profiling of tumor-infiltrating macrophages during tumor growth, Umemura, Naoki;Sugimotoz, Masahiro;Kitoh, Yusuke;Saio, Masanao;Sakagami, Hiroshi, 2020, CANCER IMMUNOLOGY IMMUNOTHERAPY, 69, 11, 2357, 2369

Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma, Tsuji, Shohei;Nakamura, Shinsuke;Maoka, Takashi;Yamada, Tetsuya;Imai, Takahiko;Ohba, Takuya;Yako, Tomohiro;Hayashi, Masahiro;Endo, Ken;Saio, Masanao;Hara, Hideaki;Shimazawa, Masamitsu, 2020, MARINE DRUGS, 18, 9

Computer-assisted image analysis of cytological specimens clarify the correlation between nuclear size and intranuclear cytoplasmic inclusions regardless of BRAFV600E mutation in papillary thyroid carcinoma, Suzuki, Midori;Moriya, Shunichi;Kobayashi, Sayaka;Nishijima, Yoshimi;Fujii, Takaaki;Ikota, Hayato;Yokoo, Hideaki;Saio, Masanao, 2021, CYTOPATHOLOGY, 32, 6, 718, 731

Th1 polarization in the tumor microenvironment upregulates the myeloid-derived suppressor-like function of macrophages, Nonaka, Kenichi;Saio, Masanao;Umemura, Naoki;Kikuchi, Arizumi;Takahashi, Takao;Osada, Shinji;Yoshida, Kazuhiro, 2021, CELLULAR IMMUNOLOGY, 369

Role of Lamin A and emerin in maintaining nuclear morphology in different subtypes of ovarian epithelial cancer, Watabe, Shiori;Kobayashi, Sayaka;Hatori, Mizuho;Nishijima, Yoshimi;Inoue, Naoki;Ikota, Hayato;Iwase, Akira;Yokoo, Hideaki;Saio, Masanao, 2022, ONCOLOGY LETTERS, 23, 1

Safety, tolerability, and anti-fibrotic efficacy of the CBP/I3-catenin inhibitor PRI-724 in patients with hepatitis C and B virus-induced liver cirrhosis: An investigator-initiated, open-label, non-randomised, multicentre, phase 1/2a study, Kimura, Kiminori;Kanto, Tatsuya;Shimoda, Shinji;Harada, Kenichi;Kimura, Masamichi;Nishikawa, Koji;Imamura, Jun;Ogawa, Eiichi;Saio, Masanao;Ikura, Yoshihiro;Okusaka, Takuji;Inoue, Kazuaki;Ishikawa, Tetsuya;Ieiri, Ichiro;Kishimoto, Junji;Todaka, Koji;Kamisawa, Terumi, 2022, EBIOMEDICINE, 80

Phosphotungstic Acid-treated Picrosirius Red Staining Improves Whole-slide Quantitative Analysis of Collagen in Histological Specimens, Mukade, Yui;Kobayashi, Sayaka;Nishijima, Yoshimi;Kimura, Kiminori;Watanabe, Akira;Ikota, Hayato;Shirabe, Ken;Yokoo, Hideaki;Saio, Masanao, 2023, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 71, 1, 11, 26

Pleasure of Diagnostic Cytopathology and My Laboratory, Saio Masanao, 2018, The Kitakanto Medical Journal, 68, 1, 69, 70

Estimating Section Thickness of Cooling System-Installed Microtome-Sliced Sections by Digital Image Analysis, Saio Masanao;Moriya Syunichi;Fujimori Misa;Hatori Mizuho;Kobayashi Sayaka;Kimura Kiminori, May 2019, The Kitakanto Medical Journal, 69, 2, 97, 104

慢性期Chagas病マウスモデルの確立と病態変化の解析, ;;;;;;;, Apr. 2021, 90回・32回, 81

機械学習のクラスター解析を用いた尿細胞診検体の細胞像と筋層浸潤の有無の関係性の解析, ;;;;;;;, Aug. 2024, 74, 3, 242

An Autopsy Case of Two Distinct, Acquired Drug Resistance Mechanisms in Epidermal Growth Factor Receptor-mutant Lung Adenocarcinoma: Small Cell Carcinoma Transformation and Epidermal Growth Factor Receptor T790M Mutation, Makoto Furugen; Kayoko Uechi; Jun Hirai; Hajime Aoyama; Masanao Saio; Naoki Yoshimi; Takeshi Kinjo; Kazuya Miyagi; Shusaku Haranaga; Futoshi Higa; Masao Tateyama; Jiro Fujita, 2015, INTERNAL MEDICINE, 54, 19, 2491, 2496

Dolichoectatic Vertebrobasilar Dissecting Aneurysm Originating from Atherosclerosis: An Autopsy Case, Katsunori Isa; Hirokuni Sakima; Noritake Kosuge; Kazuhito Kokuba; Yoshino Goya; Koh Nakachi; Satoshi Ishihara; Takashi Tokashiki; Yusuke Ohya; Masanao Saio, 2013, INTERNAL MEDICINE, 52, 16, 1821, 1823

Dolichoectatic Vertebrobasilar Dissecting Aneurysm Originating from Atherosclerosis: An Autopsy Case, Katsunori Isa; Hirokuni Sakima; Noritake Kosuge; Kazuhito Kokuba; Yoshino Goya; Koh Nakachi; Satoshi Ishihara; Takashi Tokashiki; Yusuke Ohya; Masanao Saio, 2013, INTERNAL MEDICINE, 52, 16, 1821, 1823

The enhancing effects of hyperbaric oxygen on mouse skin carcinogenesis., Hiroshi Doguchi; Masanao Saio; Shimpei Kuniyoshi; Akiko Matsuzaki; Naoki Yoshimi, Apr. 2014, Journal of toxicologic pathology, 27, 1, 67, 72

The Enhancing Effects of Hyperbaric Oxygen on Mouse Skin Carcinogenesis, Doguchi, Hiroshi; Saio, Masanao; Kuniyoshi, Shimpei; Matsuzaki, Akiko; Yoshimi, Naoki, 2014, 27, 1, 67, 72

液状化検体細胞診からセルブロック作製における脱脂綿利用の有用性, 大竹 賢太郎; 齊尾 征直; 黒島 義克; 安里 良子; 吉見 直己, May 2013, 52, 3, 271, 272

ラオス国における自己採取型器具を使用した子宮頸がん検診の検討, 黒島 義克; 大竹 賢太郎; 楾 清美; 松崎 晶子; 齊尾 征直; 吉見 直己, Jan. 2014, 53, 1, 55, 59

遠隔病理診断とデジタルパソロジー 沖縄県における遠隔病理診断, 國吉 真平; 小菅 則豪; 齊尾 征直; 吉見 直己, 2016, 34, 1, 50, 55

保健学研究科の病理・細胞診分野における私の今後の教育と研究, 齊尾 征直, Aug. 2018, 68, 3, 189, 189

細胞診にて粘液球が目立たなかった腺様嚢胞癌の1例, 熱海 恵理子; 岸本 明久; 渡口 貴美子; 伊地 隆晴; 河崎 英範; 川畑 勉; 齊尾 征直; 吉見 直己, Jul. 2018, 49, 33, 36

一部に粘液産生を伴い神経内分泌マーカー陽性の浸潤性乳管癌の一例, 阿部 奈津美; 佐藤 香織; 植野 舞; 堀越 可奈; 福田 利夫; 齊尾 征直; 佐野 孝昭; 小山 徹也; 竹尾 健, Apr. 2018, 日本臨床細胞学会雑誌, 57, Suppl.1, 296, 296

肺Langerhans細胞組織球症が疑われた女性左気胸の1例, 北爪 はるな; 嘉数 修; 大田 守雄; 當山 鉄男; 林 圭吾; 後藤 倫子; 馬場 徳朗; 小倉 加奈子; 上里 安範; 卸川 智文; 間山 泰晃; 兼城 達也; 砂川 宏樹; 座波 久光; 與那覇 俊美; 大城 直人; 青山 肇; 斉尾 征直, Jun. 2016, 沖縄医学会雑誌, 55, 1, 123, 123

滑膜肉腫との鑑別が問題となった限局性悪性胸膜中皮腫の1例, 熱海 恵理子; 平良 尚弘; 河崎 英範; 川畑 勉; 仲地 里織; 松本 裕文; 齊尾 征直; 久岡 正典; 吉見 直己, Apr. 2016, 105, 1, 440, 441

妊婦に発症した腟pseudosarcomatous fibroepithelial stromal polypの一例, 松崎 晶子; 齊尾 征直; 青山 肇; 松本 裕文; 小菅 則豪; 玉城 智子; 新垣 和也; 國吉 真平; 吉見 直己, Apr. 2016, 日本病理学会会誌, 105, 1, 477, 477

沖縄本島中部地区市町村子宮がん検診へのLBC全面導入効果, 黒島 義克; 大竹 賢太郎; 赤嶺 奈月; 青山 肇; 松崎 晶子; 齊尾 征直; 吉見 直己, Oct. 2015, 日本臨床細胞学会雑誌, 54, Suppl.2, 549, 549

腹水中に腫瘍細胞を認めたProximal-type類上皮肉腫の一例, 平田 幸也; 齊尾 征直; 西平 育子; 比嘉 美香; 瑞慶覧 陽子; 伊原 美枝子; 仲宗根 克; 國吉 真平; 小菅 則豪; 青山 肇; 吉見 直己, Oct. 2015, 日本臨床細胞学会雑誌, 54, Suppl.2, 630, 630

核所見の詳細な観察が重要と思われた大細胞神経内分泌癌の一例, 宮城 良考; 齋尾 征直; 比嘉 盛治; 知花 祐子; 仲座 良治; 青山 肇, Oct. 2015, 日本臨床細胞学会雑誌, 54, Suppl.2, 646, 646

術中迅速組織検査捺印標本にて細胞像を経験したMelanotic schwannomaの一例, 伊原 美枝子; 齊尾 征直; 仲宗根 克; 比嘉 美香; 瑞慶覧 陽子; 小菅 則豪; 青山 肇; 仲西 貴也; 新垣 和也; 吉見 直己, Apr. 2015, 日本臨床細胞学会雑誌, 54, Suppl.1, 317, 317

詳細な術材検討により卵巣原発悪性リンパ腫の併存が確認された両側卵巣漿液性腺癌の一例, 玉城 智子; 大田 多加乃; 新垣 和也; 松本 裕文; 青山 肇; 松崎 晶子; 斉尾 征直; 吉見 直己, Mar. 2015, 日本病理学会会誌, 104, 1, 361, 361

Endometrial stromal nodule with prominent hyaline plaqueの一例, 斉尾 征直; 熱海 恵理子; 國吉 真平; 青山 肇; 吉見 直己, Mar. 2015, 日本病理学会会誌, 104, 1, 363, 363

乳び胸腹水・心嚢水を呈した早産児の一例, 熱海 恵理子; 新垣 和也; 松本 裕文; 青山 肇; 松崎 晶子; 齊尾 征直; 奥 聡; 仲里 巌; 中澤 温子; 吉見 直己, Mar. 2015, 日本病理学会会誌, 104, 1, 374, 374

Cardiac papillary fibroelastoma(CPFE)3例の病理学的検討, 松崎 晶子; 玉城 智子; 松本 裕文; 小菅 則豪; 熱海 恵理子; 青山 肇; 仲西 貴也; 新垣 和也; 齊尾 征直; 吉見 直己, Mar. 2015, 日本病理学会会誌, 104, 1, 404, 404

ALK遺伝子陽性であった若年者肺癌の1切除例, 嘉数 修; 大田 守雄; 當山 鉄男; 福里 夏海; 名嘉村 敬; 伊志嶺 朝彦; 玉城 和則; 國吉 真平; 青山 肇; 斉尾 征直, Oct. 2014, 肺癌, 54, 5, 528, 528

平滑筋への分化を伴い下大静脈内より右心房内への進展を認めた低悪性度子宮内膜間質肉腫の1例, 羽柴 淳; 玉城 智子; 青山 肇; 松崎 晶子; 齊尾 征直; 吉見 直己, Sep. 2014, 日本病理学会会誌, 103, 2, 53, 53

左無気肺を来たし高周波スネア焼灼術後に胸腔鏡下左上葉切除術を施行した肺カルチノイドの1例, 宮城 怜奈; 大田 守雄; 嘉数 修; 當山 鉄男; 小倉 加奈子; 卸川 智文; 間山 泰晃; 兼城 達也; 砂川 宏樹; 稲嶺 進; 座波 久光; 與那覇 俊美; 大城 直人; 名嘉村 敬; 玉城 和則; 國吉 真平; 青山 肇; 斉尾 征直, Jun. 2014, 沖縄医学会雑誌, 53, 1, 49, 49

肺癌の剖検時に判明した播種性糞線虫症の1例, 小菅 則豪; 齊尾 征直; 玉城 智子; 青山 肇; 林 昭伸; 松崎 晶子; 吉見 直己, Apr. 2014, 診断病理, 31, 2, 108, 113

琉球大学医学部のラオス国支援活動 その一環としての細胞診, 仲宗根 克; 大竹 賢太郎; 黒島 義克; 国吉 真平; 玉城 智子; 小菅 則豪; 青山 肇; 松崎 晶子; 齊尾 征直; 吉見 直己, Apr. 2014, 日本臨床細胞学会雑誌, 53, Suppl.1, 193, 193

思春期女性に男性化徴候を起こした異所性副腎皮質癌の一例, 小菅 則豪; 齊尾 征直; 玉城 智子; 國吉 真平; 木村 太一; 青山 肇; 松崎 晶子; 吉見 直己, Mar. 2014, 日本病理学会会誌, 103, 1, 327, 327

Fibroadenoma of the vulvaの一例, 斉尾 征直; 小菅 則豪; 諸見里 秀彦; 玉城 智子; 國吉 真平; 木村 太一; 青山 肇; 松崎 晶子; 吉見 直己, Mar. 2014, 日本病理学会会誌, 103, 1, 340, 340

縦隔転移を機にTTF-1陽性小細胞癌の併存が確認された子宮体部類内膜腺癌の一例, 玉城 智子; 齊尾 征直; 渡慶次 オースティン誠; 國吉 真平; 小菅 則豪; 木村 太一; 青山 肇; 松崎 晶子; 吉見 直己, Mar. 2014, 日本病理学会会誌, 103, 1, 342, 342

腹水細胞診の異型細胞の出現を契機に悪性転化微小病変発見に至った若年者の卵巣の奇形腫の一例, 國吉 真平; 齊尾 征直; 玉城 智子; 小菅 則豪; 木村 太一; 青山 肇; 松崎 晶子; 吉見 直己, Mar. 2014, 日本病理学会会誌, 103, 1, 344, 344

Adenoma of nonpigmented ciliary epitheliumの一例, 青山 肇; 齊尾 征直; 玉城 智子; 國吉 真平; 木村 太一; 小菅 則豪; 松崎 晶子; 吉見 直己, Mar. 2014, 日本病理学会会誌, 103, 1, 355, 355

非AIDS患者である超高齢者に発生した原発性滲出性リンパ腫の1例, 松崎 晶子; 齊尾 征直; 青山 肇; 小菅 則豪; 玉城 智子; 国吉 真平; 木村 太一; 伊志嶺 朝彦; 吉見 直己, Mar. 2014, 日本病理学会会誌, 103, 1, 386, 386

子宮体癌の術中洗浄腹水を契機に診断された卵巣内頸部様粘液性境界悪性腫瘍の一例, 斉尾 征直; 青山 肇; 知花 祐子; 仲座 良治; 玉城 智子; 國吉 真平; 小菅 則豪; 木村 太一; 松崎 晶子; 吉見 直己, Oct. 2013, 日本臨床細胞学会雑誌, 52, Suppl.2, 734, 734

Induction Chemotherapyが奏功した肺癌の2例, 小倉 加奈子; 大田 守雄; 嘉数 修; 當山 鉄男; 卸川 智文; 春松 敏夫; 間山 泰晃; 尾野村 麻以; 兼城 達也; 砂川 宏樹; 稲嶺 進; 座波 久光; 與那覇 俊美; 大城 直人; 名嘉村 敬; 玉城 和則; 青山 肇; 斉尾 征直, Jun. 2013, 沖縄医学会雑誌, 52, 1, 56, 56

卵巣Krukenberg腫瘍を合併した回腸原発のAFP産生性腺癌の一例, 青山 肇; 齊尾 征直; 松崎 晶子; 吉見 直己, Apr. 2013, 日本病理学会会誌, 102, 1, 459, 459

全身転移した肺腺癌の剖検時に合併が判明した播種性糞線虫症の1例, 小菅 則豪; 齊尾 征直; 玉城 智子; 青山 肇; 林 昭伸; 松崎 晶子; 吉見 直己, Sep. 2012, 日本病理学会会誌, 101, 2, 61, 61

子宮頸がん検診を契機に発見された神経内分泌癌の1例, 黒島 義克; 大竹 賢太郎; 遠藤 理子; 安里 良子; 青山 肇; 玉城 智子; 齊尾 征直; 吉見 直己, Sep. 2012, 日本臨床細胞学会雑誌, 51, Suppl.2, 761, 761

The pre-neoplastic lesion, mucin-depleted foci, reveals as de novo high-grade dysplasia in rat colon carcinogenesis, Changxu Cui; Reika Takamatsu; Hiroshi Doguchi; Akiko Matsuzaki; Masanao Saio; Naoki Yoshimi, Apr. 2012, CANCER RESEARCH, 72, Summary international conference

下顎骨に発生した原発性骨内扁平上皮癌の1例, 松崎 晶子; 林 昭伸; 齊尾 征直; 青山 肇; 吉見 直己, Mar. 2012, 日本病理学会会誌, 101, 1, 327, 327

類内膜腺癌を合併するperitoneal keratin granulomaの一例, 城間 紀之; 齊尾 征直; 青山 肇; 松崎 晶子; 林 昭伸; 吉見 直己, Mar. 2012, 日本病理学会会誌, 101, 1, 417, 417

Extra-adrenal myelolipomaの二例, 林 昭伸; 松崎 晶子; 小菅 則豪; 青山 肇; 齋尾 征直; 吉見 直己, Mar. 2011, 日本病理学会会誌, 100, 1, 442, 442

男性乳房顆粒細胞腫の1例, 名和 正人; 細野 芳樹; 川口 順敬; 吉田 和弘; 杉崎 圭子; 齊尾 征直, Jul. 2009, 24, 3, 403, 406

癌の免疫 口腔扁平上皮癌における腫瘍内浸潤Tリンパ球増殖活性についての検討, 諏訪 達彦; 齊尾 征直; 梅村 直己; 山下 知巳; 土井田 誠; 柴田 敏之, Jan. 2007, 日本口腔科学会雑誌, 56, 1, 127, 128

びまん性大細胞型B細胞リンパ腫におけるsurvivinおよびT332抗原の発現の意義, 小島 康志; 宮内 ルミ子; 鶴見 寿; 笠原 千嗣; 高橋 健; 後藤 尚絵; 山田 俊樹; 斉尾 征直; 山田 鉄也; 冨田 栄一; 森脇 久隆; 高見 剛, Sep. 2005, 日本血液学会・日本臨床血液学会総会プログラム・抄録集, 67回・47回, 773, 773

IL-2免疫遺伝子療法下における腫瘍内浸潤マクロファージの解析, 諏訪 達彦; 齊尾 征直; 梅村 直己; 柴田 敏之, Sep. 2005, 日本口腔科学会雑誌, 54, 4, 467, 468

肝浸潤を伴ったeosinophilic fasciitisの1例, 北川 順一; 田中 優司; 澤田 道夫; 齊尾 征直; 森脇 久隆, Nov. 2004, 94, 5, 999, 1002

腹腔内破裂した多発性巨大肝膿瘍の1例, 安田 顕; 西垣 和彦; 橋本 和明; 佐々木 謙; 鷹津 久登; 湊口 信也; 後藤 雅博; 齊尾 征直; 高見 剛; 藤原 久義, May 1999, 14, 1, 7, 10

C型劇症肝炎,C型亜急性肝炎の病理形態学的特徴, 山田 鉄也; 齊尾 征直; 中山 崇, Sep. 1995, 53, 増刊 分子肝炎ウイルス病学(上), 541, 545

保健学研究科 国際保健推進室の取り組み ーなぜ、 保健学は国際化が必要かー, 齋藤貴之; 岡美智代; 篠崎博光; 金泉志保美; 辻村弘美; 齊尾征直; 時田佳治; 坂本雅昭; 久留利菜菜; 中澤理恵; 李範爽; 今井忠則; 土屋謙仕; 川島智幸, Mar. 2018

細胞診断学の楽しさを伝えられる研究室を目指して, 齊尾 征直, Feb. 2018, 68, 1, 69, 70

Interaction of glycoprotein nonmetastatic melanoma B (GPNMB) and Na plus /K plus -ATPase is involved in the progression of brain glioma, Yoko Ono; Shinsuke Chiba; Hirohito Yano; Noriyuki Nakayama; Masanao Saio; Kazuhiro Tsuruma; Masamitsu Shimazawa; Toru Iwama; Hideaki Hara, Mar. 2017, JOURNAL OF PHARMACOLOGICAL SCIENCES, 133, 3, S95, S95, Summary international conference

胸部交感神経幹から発生した縦隔神経鞘腫の2例, 大田 守雄; 嘉数 修; 當山 鉄男; 小倉 加奈子; 卸川 智文; 春松 敏夫; 間山 泰晃; 尾野村 麻以; 兼城 達也; 砂川 宏樹; 稲嶺 進; 座波 久光; 與那覇 俊美; 大城 直人; 新里 敬; 青山 肇; 斉尾 征直, Jun. 2013, 沖縄医学会雑誌, 52, 1, 58, 58

右気管支性嚢腫摘出時の気管膜様部損傷に対し胸腺による被覆を施行した1例, 川端 直人; 大田 守雄; 嘉数 修; 當山 鉄男; 小倉 加奈子; 卸川 智文; 春松 敏夫; 間山 泰晃; 尾野村 麻以; 兼城 達也; 砂川 宏樹; 稲嶺 進; 座波 久光; 與那覇 俊美; 大城 直人; 青山 肇; 斉尾 征直, Jun. 2013, 沖縄医学会雑誌, 52, 1, 58, 58

A case of extra-adrenal myelolipoma in the renal hilum, HAYASHI Akinobu; MIYAZATO Tomonori; MATSUZAKI Akiko; KOSUGE Noritake; AOYAMA Hajime; SAIO Masanao; YOSHIMI Naoki, 30 Jul. 2011, 28, 3, 195, 197

A CASE OF GLYCOGEN-RICH CLEAR CELL CARCINOMA OF THE BREAST, HORI Keiichi; NARITA Hiroshi; SAIO Masanao, 25 Sep. 2008, 69, 9, 2173, 2177

O-21 術後8年で再発した多嚢胞性腹膜中皮腫の1例(骨・軟部,中皮・体腔液, 第48回日本臨床細胞学会総会), 餌取 文昌; 榊間 利政; 松山 昌史; 吉田 めぐみ; 山田 鉄也; 齊尾 征直; 山田 泰広; 松永 研吾, 22 Mar. 2007, 46, 1, 149, 149

IL-2療法下における腫瘍内浸潤マクロファージとT細胞の相互関連, 諏訪 達彦; 齊尾 征直; 玉川 紀之; 柴田 敏之; 高見 剛, May 2004, 日本病理学会会誌, 93, 1, 294, 294

25. 胸水貯留で再発した臀部血管肉腫の1例(第82回日本肺癌学会中部支部会)(支部活動), 石黒 崇; 澤 祥幸; 吉田 勉; 三輪 美津留; 米田 和夫; 山田 鉄也; 斉尾 征直; 高見 剛, 20 Apr. 2003, 43, 2, 156, 156

培養細胞を用いたセルブロック作製条件の検討, 櫛引 来明; 兼平 裕貴; 大井 瑞葉; 西島 良美; 小林 さやか; 齊尾 征直, Aug. 2023, 73, 3, 247, 247

慢性期シャーガス病マウスモデルを用いたキノン含有化合物の抗原虫作用の検討, 井上 渚; 鬼塚 陽子; 古川 眞衣; 須藤 豊; 西島 良美; 齊尾 征直; 嶋田 淳子, Aug. 2023, 73, 3, 257, 257

今後、臨床検査技師に期待される役割について, 長田 誠; 小林 沙綾; 柴沼 里桜; 高橋 佳佑; 半田 正; 村上 有希; 齊尾 征直, May 2023, 72回, np533, np533

子宮頸部細胞診のASC-H判定と年齢との関係性の検討, 高島 希未; 小林 さやか; 西島 良美; 齊尾 征直, Oct. 2022, 61, Suppl.2, 479, 479

細胞内細胞現象の捉え方と研究の動向, 齊尾 征直; 大井 瑞葉; 兼平 裕貴; 櫛引 来明; 石澤 瑛史; 池田 琴音; 大内 美月; 高島 希未; 百足 ゆい; 小林 さやか; 西島 良美, Oct. 2022, 61, Suppl.2, 541, 541

Sirius Red染色におけるリンモリブデン酸前処理の非特異的染色性抑制効果の検討, 百足 ゆい; 小林 さやか; 西島 良美; 齊尾 征直, Oct. 2022, 111, 2, 102, 102

卵巣漿液性腺癌原発巣におけるLaminA,LaminB1,LaminB2の卵管との発現比較, 大内 美月; 小林 さやか; 西島 良美; 齊尾 征直, Oct. 2022, 111, 2, 106, 106

マウスモデルを用いた慢性期シャーガス病治療薬の探索, 古川 眞衣; 鬼塚 陽子; 西島 良美; 齊尾 征直; 嶋田 淳子, Aug. 2022, 72, 3, 321, 322

ヒト肝組織のSirius Red染色におけるリンモリブデン酸前処理の非特異的染色性低減効果の検討, 百足 ゆい; 小林 さやか; 西島 良美; 齊尾 征直, Aug. 2022, 72, 3, 323, 323

マウスモデルを用いた慢性期シャーガス病治療薬の探索, 古川 眞衣; 鬼塚 陽子; 西島 良美; 齊尾 征直; 嶋田 淳子, Aug. 2022, 72, 3, 321, 322

ヒト肝組織のSirius Red染色におけるリンモリブデン酸前処理の非特異的染色性低減効果の検討, 百足 ゆい; 小林 さやか; 西島 良美; 齊尾 征直, Aug. 2022, 72, 3, 323, 323

BRAFV600E変異の有無と甲状腺乳頭癌の細胞学的特徴の検討, 鈴木 みどり; 守谷 駿一; 羽鳥 瑞歩; 廣江 珠希; 小林 さやか; 西島 良美; 齊尾 征直, May 2021, 60, Suppl.1, 252, 252

慢性期Chagas病マウスモデルの確立と病態変化の解析, 鬼塚 陽子; 村田 涼子; 小倉 啓輔; 佐藤 涼香; アセンシオ・タチアナ; 小林 さやか; 齊尾 征直; 嶋田 淳子, Apr. 2021, 90回・32回, 81, 81

魚肉ソーセージ切片と画像解析を組み合わせた検量線作製の試み, 守谷 駿一; 廣江 珠希; 羽鳥 瑞歩; 藤森 美沙; 柿澤 仁美; 小林 さやか; 西島 良美; 齊尾 征直, Aug. 2019, 69, 3, 294, 295

滑走式と回転式ミクロトームにおける薄切時摩擦熱の検討, 廣江 珠希; 羽鳥 瑞歩; 守谷 駿一; 柿澤 仁美; 齊尾 征直, Aug. 2019, 69, 3, 297, 297

滑走式ミクロトームの型の違いと標本薄切に与える影響について, 羽鳥 瑞歩; 守谷 駿一; 藤森 美沙; 柿澤 仁美; 廣江 珠希; 小林 さやか; 西島 良美; 齊尾 征直, Aug. 2019, 69, 3, 305, 305

義歯安定剤とミクロトーム冷却装置を用いた連続薄切条件の検討, 羽鳥 瑞歩; 齊尾 征直; 守谷 駿一; 藤森 美沙; 農見 友梨; 小林 さやか, Apr. 2019, 108, 1, 458, 458

ミクロトーム冷却装置を用いた連続薄切の精度の検討, 守谷 駿一; 齊尾 征直; 羽鳥 瑞歩; 藤森 美沙; 農見 友梨; 小林 さやか, Apr. 2019, 108, 1, 458, 458

子宮頸部細胞診で診断しえた乳頭状扁平上皮癌, 西平 育子; 仲宗根 克; 平田 幸也; 比嘉 美香; 瑞慶覧 陽子; 伊原 美枝子; 新垣 和也; 松崎 晶子; 齊尾 征直; 吉見 直己, Oct. 2016, 55, Suppl.2, 504, 504

尿細胞診で尿路上皮癌との鑑別に苦慮したウイルス性出血性膀胱炎の一例, 玉城 智子; 斉尾 征直; 比嘉 美香; 瑞慶覧 陽子; 西平 育子; 伊原 美枝子; 仲宗根 克; 仲西 貴也; 松崎 晶子; 吉見 直己, Apr. 2015, 54, Suppl.1, 261, 261

膵solid-pseudopapillary neoplasmの一症例, 赤嶺 奈月; 吉見 直己; 齋尾 征直; 松崎 晶子; 宮城 恵巳; 上地 英朗, Oct. 2013, 52, Suppl.2, 718, 718

髄腔内に播種を認めたAtypical teratoid/rhabdoid tumorの一例, 伊原 美枝子; 仲宗根 克; 川崎 美香; 松本 裕文; 熱海 恵理子; 松崎 晶子; 玉城 智子; 吉見 直己; 加藤 誠也; 齊尾 征直, May 2013, 52, Suppl.1, 228, 228

捺印細胞診の併用が術中迅速診断に有用であった骨芽細胞腫の一例, 川崎 美香; 仲宗根 克; 松本 裕文; 松崎 晶子; 豊田 善成; 熱海 恵理子; 林 昭伸; 吉見 直己; 加藤 誠也; 齊尾 征直, Sep. 2012, 51, Suppl.2, 752, 752

ラオス国での自己採取型子宮頸癌検診の検討, 黒島 義克; 大竹 賢太郎; 遠藤 理子; 安里 良子; 加藤 才子; 鈴木 裕; 楾 清美; 松崎 晶子; 齋尾 征直; 吉見 直己, Sep. 2011, 50, Suppl.2, 553, 553

甲状腺硝子化索状腫瘍の一例, 瑞慶覧 陽子; 赤嶺 奈月; 宮城 恵巳; 上地 英朗; 松崎 晶子; 齊尾 征直; 吉見 直己, Sep. 2011, 50, Suppl.2, 610, 610

動脈硬化症を背景とした椎骨脳底動脈解離から脳幹梗塞を来した1剖検例, 小菅 則豪; 齊尾 征直; 林 昭伸; 松崎 晶子; 吉見 直己, Mar. 2011, 100, 1, 410, 410

paragangliomaの術中迅速病理診断において、捺印細胞診が有用であった一例, 林 昭伸; 齊尾 征直; 熱海 恵理子; 松本 裕文; 小菅 則豪; 松崎 晶子; 仲宗根 克; 豊田 善成; 加藤 誠也; 吉見 直己, Sep. 2010, 49, Suppl.2, 659, 659

甲状腺好酸性細胞腺腫の一例, 川崎 美香; 仲宗根 克; 松崎 晶子; 宮国 孝男; 西平 育子; 豊田 善成; 松本 裕文; 加藤 誠也; 吉見 直己; 齊尾 征直, May 2010, 48, 1, 55, 55

カロリー制限によるDMH誘発ラット大腸前癌病変抑制効果, 富田 真理子; 森岡 孝満; 松崎 晶子; 齊尾 征直; 富田 秀司; 吉見 直己, Mar. 2010, 99, 1, 244, 244

RCHOP治療施行されたびまん性大細胞性B細胞性リンパ腫患者における血清可溶性CD27の臨床的意義の検討, 後藤 尚絵; 二宮 空暢; 兼村 信宏; 北川 順一; 吉川 武志; 笠原 千嗣; 原 武志; 鶴見 寿; 鬼頭 勇輔; 斉尾 征直; 高見 剛, Jun. 2009, 日本リンパ網内系学会会誌, 49, 88, 88

IgG4関連疾患に伴って発症したと考えられる両眼窩MALTリンパ腫の1例, 二宮 空暢; 後藤 尚絵; 兼村 信宏; 北川 順一; 吉川 武志; 笠原 千嗣; 原 武志; 鶴見 寿; 鬼頭 勇輔; 斉尾 征直; 高見 剛; 清水 進一, Jun. 2009, 日本リンパ網内系学会会誌, 49, 139, 139

びまん性大細胞型B細胞リンパ腫におけるApoTag発現の意義, 小島 康志; 鶴見 寿; 笠原 千嗣; 後藤 尚絵; 福野 賢二; 山田 俊樹; 斉尾 征直; 安田 一朗; 森脇 久隆; 高見 剛, Sep. 2006, 臨床血液, 47, 9, 1265, 1265

Soluble CD27 as a tumor marker of central nervous system lymphoma, S Murase; N Sakai; K Takenaka; H Yamakawa; K Nakatani; H Sakai; T Itoh; S Yoshimura; T Takami; M Saio, 1997, 11TH INTERNATIONAL CONGRESS OF NEUROLOGICAL SURGERY, VOLS 1 AND 2, 799, 803

わからんがわかるへ病理解剖, Single work, Jan. 2011

病理学, Contributor, 15 Oct. 2022, xv, 309p, ISBN: 9784260049863

Are tumor-infiltrating macrophages derived from monocyte-lineage belonging to the myeloid-derived suppressor cell?, TAKAMI Tsuyoshi; GOTOH Naoe; KITOH Yusuke, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gifu University, 2009, 2011, The marker profile, production of cytokine and chemokine, and antigen-presenting capability were studied to clarify the origin of tumor-infiltrating macrophages(TIM). Our results clearly showed that TIM was the hetrogeneous cell population having both capabilities of tumor-suppressing(M1) macrophage and tumor-promoting(M2) macrophages. On the other hand, the treatment of TIM with GM-CSF and siRNA for M-CSF induced the intra-cellular signal transducing molecules such as STAT-1, STAT-5, and STAT-6 of which are necessary for maturation toward antigen-presenting dendritic cells, nevertheless the maker-profiles of treated TIM did not change significantly. However both of the GM-CSF and siRNA for M-CSFR treated and non-treated TIM revealed similar antigen presenting capabilities in the system using OVA-specific TCR transgenic mice. Altogether it was clarified that the phenotype of TIM was reflecting the invading tumor microenvironment, and not certain cell type such as myeloid-derived suppressor cells, but was the cell that still keeped plasticity and could be changed by surrounding microenvironment., 21590415

Establishment of method to re-educate mecrophage differentiation towards dendritic cells on the view of regeneration medicine, SAIO Masanao; TAKAMI Tsuyoshi; YOSHIMI Naoki; TOMITA Mariko, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), University of the Ryukyus, 2009, 2011, Granulocyte macrophage colony stimulating factor(GM-CSF) treatment alone could not alter expression level of macrophage differentiation. On the other hands, when the TIM was treated with GM-CSF and siRNA for macrophage colony stimulating factor(M-CSF) receptor(M-CSFR) altered the expression of signal pathway proteins towards dendritic cell like feature. Above findings indicated we successfully re-educated(re-differentiated) TIM towards monocyte-derived dendritic cells like population and we showed the macrophage plasticity., 21590416

The analysis of inflammatory cascade between antigen specific CTLs and liver injury using hepatitis model, KIMURA Kiminori; KAKIMI Kazuhiro; NAGAKI Masahito; SAIO Masanao; KURACHI Makoto; UEHA Satoshi; MATSUSHIMA Kouji, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Tokyo Metropolitan Organization for Medical Research, 2008, 2010, There are many uncertain points for regarding with leukocytes movement in the liver, especially interaction between liver sinus endothelial cells (LSECs) and cytotoxic T lymphocytes (CTLs). We examined role of CD44 for these interaction using hepatitis model. CTLs were administered into Hepatitis B virus transgenic mice (HBVTg) mice and HBVTgxCD44 knock out (KO) mice, and alanine aminotransferase activity, number of intrahepatic leukocytes, cytokine and chemokine mRNA level were examined. To determine the number and distribution of CTLs in the liver CFSE-labeled CTLs was administered into HBVTg with or without CD44 mice. sALT activity increased since 12 h though it had declined to 4 h in the CD44KOxHBVTg mice after CTLs injection. Similarly, the levels of Tumor necrosis factor (TNF) a, Interferon (IFN) g, Macrophage inflammatory protein (MIP)-2 mRNAs reduced in 4 h though it had been increased since 12 h in the CD44KOxHBVTg mice. The number of apoptotic hepatocytes increased intentionally at 24 h in the CD44KOxHBVTg livers, and it thought to be due to lower activity of initial nuclear factor kappaB (NF-kB). Although the number of CTLs exhibited lower at 4 h in the CD44KOxHBVTg livers the difference of Intercellular adhesion molecule (ICAM)-1 and CD86 expression on LSECs was not detected. CD44 on LSECs exerts important roles for CTLs migration into the hepatocytes. However, since CD44 deficient state was exacerbate hepatic injury, attention is necessary for hepatitis treatment as CD44 target therapy., 20390203

Analysis of brain specific differentiation and maturation of tumor-infiltrating dendritic cells in glioma, SAIO Masanao; TAKAMI Tsuyoshi; OHE Naoyuki; ALAN B Frey; ROZA Adany; MARGIT Balazs, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Gifu University, 2006, 2008, 18390393

Detection and regulation of hepatic diseases targeting TGF-β activation reaction., KOJIMA Soichi; SAIO Masanao, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), RIKEN, 2004, 2006, Transforming growth factor (TGF)-β, a 25 kD dimeric polypeptide playing a pivotal role in the pathogenesis of liver diseases, is produced as a high molecular weight latent form, and activated by plasmin (PLN) and plasma kallikrein (PLK) during pathogenesis of liver diseases. Blockage of the activation reaction with low molecular weight protease inhibitors prevented the development of the diseases in animal models. Based upon these findings, here, we found that (1) PLN and PLK cleaved between K56-L57 and R58-L59 in LAP portion of human latent TGF-β1, respectively. We produced antibodies that specifically recognize the neo-epitopes formed by protease degradation, namely the cut ends of each cleavage site. The anti-R58 antibodies strongly stained liver sections from patients with fulminant hepatitis. (2) The anti-L59 antibodies were successively used to establish ELISA to detect LAP degradation fragments in serum of mouse impaired liver regeneration model as well as rat CCl4 and bile duct ligation hepatic fibrosis models, showing a good correlation with serum transamidase levels and hepatic hydroxyproline levels. (3) Decoy peptides containing the cleavage sites blocked the activation of TGF-β in the hepatic stellate cells and improved hepatic regeneration in the mouse model. (4) In scleroderma TGF-β2 is the main isoform and MMP, but not PLN and PLK, appeared to be involved in its activation reaction. (5) CXZ, which has been shown to suppress phosphorylation of Smad, successfully improved hepatic regeneration in the mouse model. These results suggest that a PLN/PLK-dependent activation reaction occurs around hepatic stellate cells to produce active TGF-β, which may induce fibrosis and inhibit the proliferation of hepatocytes, thereby addressing a potential use for decoy peptides in hepatitis therapy. These results also suggest a potential usage of a LAP degradate as a novel biomarker for liver fibrosis., 16390215

Development of immunotherapy for glioma utilizing cell-free protein expression system, SAIO Masanao; TAKAMI Tsuyoshi; OHE Naoyuki, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gifu University, 2004, 2005, We cloned cDNA of murine Interleukin (IL)-2 and 15, and then the cDNAs were re-cinstituted into pIVEX vector for cell free E. coli extract based protein expression system. The cloned vectors were mixed with cell free protein expression mixture for 24 hours with 900 rpm at 30C. Unfortunately, the yield of the protein in supernatant was very low due to precipitation of the protein. Therefore, we utilized the other cell free protein expression system ; yeast extract based system. The products from yeast extract based IL-2 and IL-15 were soluble, and we could purify the protein by Histidine 6 mer with Ni column. The purified proteins were able to stimulate splenocytes. However the yield of each protein was approximately 100ng per synthesis. Therefore, we could not utilized them in vivo analysis. In turn, we prepared IL-2, soluble form tumor necrosis factor receptor II (sTNFRII) transduced MCA 38 murine colon carcinoma sub-lines and GL261 murine glioma sub-lines ; MCA/mock,MCA/sTNFRII,MCA/IL-2,MCA/double,GL261/mock,GL261/sTNFRII,GL261/IL-2,GL261/double. We intra-cranially, and subcutaneously inoculated each sub-lines and analyzed tumor infiltrating CD8^+T-cells (CD8^+TIL) and tumor associated macrophages (TAM). In MCA38, MCA/double showed the longest survival. While, GL261/IL-2 showed the longest survival in vivo in GL261 groups. Although there was not significant characteristic change of CD8^+TIL among groups, almost 90 % of TAM recovered from MCA/double got apoptotic in in vitro culture. By in vivo CD4 or CD8 depletion, tumor growth suppression observed in MCA/double was strongly interfered. These data suggested that acquired immunity could be strongly induced by the combination of IL-2 and blocking of TNF by sTNFRII rather than IL-2 alone. Our data also suggested that balance of acquired immunity and innate immunity for exclusion of tumor cells would demand on the character of tumor cells. In the future, we would like to explore the mechanism how to mature macrophages and dendritic cells in tumor environment by utilizing the present results and methods., 16591437

The development of immunotherapy for human brain tumor using molecular biothechnology, TAKAMI Tsuyoshi; SAIO Masanao; SAKAI Noboru, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gifu University, 2002, 2003, The aim of this research was development of advanced method to clarify the peptides of tumor antigens, and thus modified HLA cDNAs were introduced to human cultured tumor cell lines to obtain and to purify its gene products from the culture supernatants. In this study the cDNA of HLA-24 that is one of the major haplotype in Japanese was introduced into the human brain tumors of which still reveal poor prognoses. Three modified HLA-A24 cNDAs, whole 1098bp, 1067bp of which was deleted the gene coding cytoplasmic portion, and 881bp coding extramembrane part were inserted into the vector gene having histidine-tag and were introduced into the five human glioblastoma cell lines after cloning. The gene products were screened by anti-histidine coating and anti-HLA antibody (W6/32) detecting ELISA, and culture supernatants of four cell lines, A24 1067bp introduced, and A24 881bp introduced SNB 19 and U373MG revealed positive reaction. Among them A24 1067 introduced U373MG (named U373-A24-1067) gave highest reaction, and thus following study were focused on the U373-A24-1067. Immunohistochemical staining showed positive reaction of U373-A24-1067 with anti histidine antibody though anti HLA-A24 antibody gave no significant reaction, thus it was considered that introduced gene was actively working. The culture supernatant of U373-A24-1067 had protein of which was purified by cobalt affinity column and was reacted with anti-histidine and W6/32 at 42 kDa by western blotting after SDS-PAGE. Also affinity purified fragment had 12 kDa protein that was reacted with anti beta 2 microglobulin, thus it was considered that U373-A24-1067 produced modified HLA-A24 associating with beta 2 microglobulin. As described above, this study has been succeeded to establish the method that is able to purify the antigenic peptides by constructing secretory HLA-A24 molecule associating with beta 2 microglobulin in culture supernatant. This result will contribute to clarify the tumor antigen peptides and to develop immunotherapy for tumor., 14571305

Human hepatoma antigen analyzed by genetic engineering method, TAKAMI Tsuyoshi; NAKAYAMA Takashi; SAIO Masanao, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Gifu University School of Medicine, 1997, 1998, Human hepatoma cell line, Hep.3B2.1-7 that has no HLA-A24 gene expression, has been transduced of HLA-A24 cDNA by using mammalian cell line expression vector pcDNA3 .1 in order to carry the endogenous antigenic peptides on its cell surface. The acidic eluate of cloned HLA-A24 expressing Hep.3B2.1-7 (Hep.3B.A24) demonstrated seven significant peakes that were different from wild type Hep.3B2.1-7 and moke-transfected Hep.3B2.1-7 after FPLO fractionations. One out of seven peptide fraction had anchoring motief for HIA-A24 at second (L) and tenth (K) positions, while two histon H2A, one HLA-A68 binding peptide of macrophage migration inhibiting factor, one HIA-B35 binding peptide, and two unknown peptides were clarified from remaining six fractions. The homology research of HLA-A24 binding peptide obtained in present study demonstrated no homologous protein in data base. In conclusion, present study is possible to clarify a novel HLA-A24 binding peptide, and HLA.molecules enforced to express by genetic engineering method will open a new avenue for the research in tumor-antigenic peptides., 09670181

1996, 1996, 08770152

Significance of Lamins as nuclear stiffness maintenance protein on ovarian cancer invasion and metstasis, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Gunma University, 01 Apr. 2021, 31 Mar. 2024, 21K09533

01 Apr. 2023, 31 Mar. 2026, 23K08815