研究者データベース

小保方 優
オボカタ マサル
循環器内科
助教
Last Updated :2024/03/29

研究者基本情報

研究者

  • 氏名

    小保方 優, オボカタ マサル

基本情報

  • 研究者氏名(日本語)

    小保方, 優
  • 研究者氏名(カナ)

    オボカタ, マサル
  • プロフィール

    心不全、特に左室駆出率の保たれた心不全(Heart failure with preserved ejection fraction: HFpEF)の病態・診断に焦点をあて、心エコーと右心カテーテルを使った臨床研究を行っています。2016年から2019年の約3年半の間、HFpEF研究の最前線である米国Mayo Clinic, Cardiovascular MedicineのDr. Barry Borlaugのラボに留学したくさんの研究をさせていただきました。現在は、群馬大学医学部附属病院で臨床業務をしながら、HFpEFの臨床研究を続けています。国内外においてHFpEF研究の最前線にたちたいと考えています。よろしくお願いいたします。

論文上での記載著者名

  • Masaru Obokata

所属

  • 群馬大学, 医学部附属病院, 助教

学歴

  • 2012年04月, 2015年03月, 群馬大学大学院, 医学系研究科
  • 2001年04月, 2007年03月, 群馬大学, 医学部, 医学科

学位

  • 医学博士

所属学協会

  • 日本循環器学会
  • 日本心臓病学会
  • 日本心不全学会
  • 日本心エコー図学会
  • 日本内科学会

経歴

  • 2019年09月, 9999年, 群馬大学医学附属病院, 循環器内科, 助教, 助教相当
  • 2016年05月, 2019年08月, メイヨークリニック, 心臓血管部門, リサーチフェロー, 研究員・ポスドク相当
  • 2014年04月, 2016年04月, 群馬大学医学附属病院, 循環器内科, 助教, 助教相当
  • 2010年04月, 2012年03月, 前橋赤十字病院, 心臓血管内科, 後期レジデント
  • 2009年04月, 2010年03月, 群馬大学医学部附属病院, 循環器内科, 後期レジデント
  • 2007年04月, 2009年03月, 群馬県立病院群, 初期臨床研修医
  • 群馬大学

研究活動情報

研究分野

  • ライフサイエンス, 循環器内科学, 臨床心不全学

研究キーワード

  • 左室駆出率の保たれた心不全
  • 心エコー図検査
  • 血行動態

論文

  • The Authors Reply., Masaru Obokata,Yogesh N V Reddy,Barry A Borlaug, 2019年10月, JACC. Cardiovascular imaging, 12, 10, 2098, 2099
  • The neurohormonal basis of pulmonary hypertension in heart failure with preserved ejection fraction., Masaru Obokata,Garvan C Kane,Yogesh N V Reddy,Vojtech Melenovsky,Thomas P Olson,Petr Jarolim,Barry A Borlaug, 2019年12月01日, European heart journal, 40, 45, 3707, 3717, 研究論文(学術雑誌)
  • Assessment and Implications of Right Ventricular Afterload in Tetralogy of Fallot., Alexander C Egbe,Nathaniel W Taggart,Yogesh N V Reddy,Mahir Sufian,Keerthana Banala,Rahul Vojjini,Maria Najam,Karim Osman,Masaru Obokata,Barry A Borlaug, 2019年12月01日, The American journal of cardiology, 124, 11, 1780, 1784, 研究論文(学術雑誌)
  • Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts., Hiroaki Sunaga,Norimichi Koitabashi,Tatsuya Iso,Hiroki Matsui,Masaru Obokata,Ryo Kawakami,Masami Murakami,Tomoyuki Yokoyama,Masahiko Kurabayashi, 2019年08月14日, Scientific reports, 9, 1, 11841, 11841, 研究論文(学術雑誌)
  • Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension., Seki M,Furukawa N,Koitabashi N,Obokata M,Conway SJ,Arakawa H,Kurabayashi M, 2019年, PloS one, PloS one, 14, 8, e0220795, 研究論文(学術雑誌)
  • Endothelium-dependent and independent coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction., Jeong Hoon Yang,Masaru Obokata,Yogesh N V Reddy,Margaret M Redfield,Amir Lerman,Barry A Borlaug, 2020年03月, European journal of heart failure, 22, 3, 432, 441, 研究論文(学術雑誌)
  • Effects of Interatrial Shunt on Pulmonary Vascular Function in Heart Failure With Preserved Ejection Fraction., Obokata M,Reddy YNV,Shah SJ,Kaye DM,Gustafsson F,Hasenfuβ G,Hoendermis E,Litwin SE,Komtebedde J,Lam C,Burkhoff D,Borlaug BA, 2019年11月26日, Journal of the American College of Cardiology, Journal of the American College of Cardiology, 74, 21, 2539, 2550, 研究論文(学術雑誌)
  • Noninvasive evaluation of pulmonary artery pressure during exercise: the importance of right atrial hypertension., Masaru Obokata,Garvan C Kane,Hidemi Sorimachi,Yogesh N V Reddy,Thomas P Olson,Alexander C Egbe,Vojtech Melenovsky,Barry A Borlaug, 2020年02月, The European respiratory journal, 55, 2, 研究論文(学術雑誌)
  • The haemodynamic basis of lung congestion during exercise in heart failure with preserved ejection fraction., Yogesh N V Reddy,Masaru Obokata,Brandon Wiley,Katlyn E Koepp,Caitlin C Jorgenson,Alexander Egbe,Vojtech Melenovsky,Rickey E Carter,Barry A Borlaug, 2019年12月01日, European heart journal, 40, 45, 3721, 3730, 研究論文(学術雑誌)
  • Adverse Renal Response to Decongestion in the Obese Phenotype of Heart Failure With Preserved Ejection Fraction., Yogesh N V Reddy,Masaru Obokata,Jeffrey M Testani,G Michael Felker,W H Wilson Tang,Omar F Abou-Ezzeddine,Jie-Lena Sun,Hrishikesh Chakrabothy,Steven McNulty,Sanjiv J Shah,Gregory D Lewis,Lynne W Stevenson,Margaret M Redfield,Barry A Borlaug, 2020年02月, Journal of cardiac failure, 26, 2, 101, 107, 研究論文(学術雑誌)
  • The relationship between antecedent creatinine decreases and outcomes in patients undergoing hemodialysis., Tomonari Harada,Hidemi Sorimachi,Masaru Obokata,Hiroaki Sunaga,Hideki Ishida,Kyoko Ito,Tetsuya Ogawa,Yoshitaka Ando,Masahiko Kurabayashi,Kazuaki Negishi, 2020年01月, Hemodialysis international. International Symposium on Home Hemodialysis, 24, 1, 89, 98, 研究論文(学術雑誌)
  • Clinical efficacy of optical coherence tomography-guided versus intravascular ultrasound-guided rotational atherectomy for calcified coronary lesion., Norihiro Kobayashi,Yoshiaki Ito,Masahiro Yamawaki,Motoharu Araki,Masaru Obokata,Yasunari Sakamoto,Shinsuke Mori,Masakazu Tsutsumi,Yohsuke Honda,Kenji Makino,Shigemitsu Shirai,Masafumi Mizusawa,Keisuke Hirano, 2019年12月17日, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 研究論文(学術雑誌)
  • Functional mitral regurgitation and left atrial myopathy in heart failure with preserved ejection fraction., Maria Tamargo,Masaru Obokata,Yogesh N V Reddy,Sorin V Pislaru,Grace Lin,Alexander C Egbe,Rick A Nishimura,Barry A Borlaug, 2020年03月, European journal of heart failure, 22, 3, 489, 498, 研究論文(学術雑誌)
  • Early Lifestyle Modification Is an Essential Step in Telemedicine for Heart Failure., Norimichi Koitabashi,Masaru Obokata,Masahiko Kurabayashi, 2020年02月25日, Circulation journal : official journal of the Japanese Circulation Society, 84, 3, 380, 381, 研究論文(学術雑誌)
  • Doppler-Derived Arterial Load Indices Better Reflect Left Ventricular Afterload Than Systolic Blood Pressure in Coarctation of Aorta., Alexander C Egbe,Yogesh N V Reddy,Masaru Obokata,Barry A Borlaug, 2020年02月, Circulation. Cardiovascular imaging, 13, 2, e009672, 研究論文(学術雑誌)
  • Quality of life in heart failure with preserved ejection fraction: importance of obesity, functional capacity, and physical inactivity., Yogesh N V Reddy,Aruna Rikhi,Masaru Obokata,Sanjiv J Shah,Gregory D Lewis,Omar F AbouEzzedine,Shannon Dunlay,Steven McNulty,Hrishikesh Chakraborty,Lynne W Stevenson,Margaret M Redfield,Barry A Borlaug, 2020年03月09日, European journal of heart failure, 研究論文(学術雑誌)
  • Clinical features of dermatomyositis associated with anti-MDA5 antibodies by age., Koichi Yamaguchi,Aya Yamaguchi,Yuji Onuki,Miki Itai,Chiharu Kashiwagi,Kazutaka Takehara,Shuhei Aoki,Azusa Kanaya,Kohei Taguchi,Kazue Umetsu,Kazuma Oshima,Megumi Uchida,Hayato Kimura,Morimitsu Kasahara,Masao Takemura,Kenichiro Hara,Akiko Sekiguchi,Sei-Ichiro Motegi,Yoshinao Muro,Masao Nakasatomi,Rena Motohashi,Toru Sakairi,Junichi Nakagawa,Keiju Hiromura,Masaru Obokata,Masahiko Kurabayashi,Toshitaka Maeno, 2020年03月30日, Modern rheumatology, 1, 9, 研究論文(学術雑誌)
  • Heightened Dependence of Left-Heart Filling Pressures on Right-Heart Failure in Congenital Heart Disease., Alexander C Egbe,Rahul Vojjini,Mohamed Badawy,Vaibhav Jain,Crystal R Bonnichsen,Yogesh N V Reddy,Masaru Obokata,Barry A Borlaug, 2020年02月26日, The Canadian journal of cardiology, 研究論文(学術雑誌)
  • Targeting pulmonary capillary permeability to reduce lung congestion in heart failure: a randomized, controlled pilot trial., Glenn M Stewart,Bruce D Johnson,Dennis L Sprecher,Yogesh N V Reddy,Masaru Obokata,Steven Goldsmith,Brad Bart,Anna Oughton,Christina Fillmore,David J Behm,Barry A Borlaug, 2020年03月30日, European journal of heart failure, 研究論文(学術雑誌)
  • Obesity-Related Heart Failure with Preserved Ejection Fraction: Pathophysiology, Diagnosis, and Potential Therapies., Tomonari Harada,Masaru Obokata, 2020年07月, Heart failure clinics, 16, 3, 357, 368, 研究論文(学術雑誌)
  • Transient T-wave Pseudonormalization following Pheochromocytoma Crisis, Masaru Obokata,Yoshiaki Kaneko,Hiroaki Yagi,Masahiko Kurabayashi, 2010年, INTERNAL MEDICINE, 49, 9, 873, 874
  • Right ventricular dysfunction and pulmonary hypertension in heart failure with preserved ejection fraction, Masaru Obokata,Barry A. Borlaug, 2016年12月, EUROPEAN JOURNAL OF HEART FAILURE, 18, 12, 1488, 1490
  • Left Ventricular Filling Pressures in Heart Failure With Preserved Ejection Fraction Is the Tail Now Wagging the Dog?, Masaru Obokata,Barry A. Borlaug, 2017年11月, JACC-HEART FAILURE, 5, 11, 802, 804
  • Role of Diastolic Stress Testing in the Evaluation for Heart Failure With Preserved Ejection Fraction: A Simultaneous Invasive-Echocardiographic Study, Masaru Obokata,Garvan C. Kane,Yogesh N. V. Reddy,Thomas P. Olson,Vojtech Melenovsky,Barry A. Borlaug, 2017年02月, CIRCULATION, 135, 9, 825, 838, 研究論文(学術雑誌)
  • Is it time to recognize a new phenotype? Heart failure with preserved ejection fraction with pulmonary vascular disease, Barry A. Borlaug,Masaru Obokata, 2017年10月, EUROPEAN HEART JOURNAL, 38, 38, 2874, 2878
  • Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction, Masaru Obokata,Yogesh N. V. Reddy,Sorin V. Pislaru,Vojtech Melenovsky,Barry A. Borlaug, 2017年07月, CIRCULATION, 136, 1, 6, +, 研究論文(学術雑誌)
  • Response by Obokata and Borlaug to Letter Regarding Article, "Role of Diastolic Stress Testing in the Evaluation for Heart Failure With Preserved Ejection Fraction: A Simultaneous Invasive-Echocardiographic Study", Masaru Obokata,Barry A. Borlaug, 2017年07月, CIRCULATION, 136, 4, 430, 431
  • Long-term cardiovascular changes following creation of arteriovenous fistula in patients with end stage renal disease, Yogesh N. V. Reddy,Masaru Obokata,Patrick G. Dean,Vojtech Melenovsky,Karl A. Nath,Barry A. Borlaug, 2017年06月, EUROPEAN HEART JOURNAL, 38, 24, 1913, 1923, 研究論文(学術雑誌)
  • Arterial Stiffening With Exercise in Patients With Heart Failure and Preserved Ejection Fraction., Reddy YNV,Andersen MJ,Obokata M,Koepp KE,Kane GC,Melenovsky V,Olson TP,Borlaug BA, 2017年07月, Journal of the American College of Cardiology, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 70, 2, 136, 148, 研究論文(学術雑誌)
  • Left atrial strain and compliance in the diagnostic evaluation of heart failure with preserved ejection fraction., Reddy YNV,Obokata M,Egbe A,Yang JH,Pislaru S,Lin G,Carter R,Borlaug BA, 2019年07月, European journal of heart failure, European journal of heart failure, 21, 7, 891, 900
  • Sex differences in left ventricular afterload and diastolic function are independent from the aortic size., Sorimachi H,Kurosawa K,Yoshida K,Obokata M,Noguchi T,Naka M,Tange S,Kurabayashi M,Negishi K, 2019年, PloS one, PloS one, 14, 4, e0214907
  • Hemodynamic Effects of Weight Loss in Obesity: A Systematic Review and Meta-Analysis., Reddy YNV,Anantha-Narayanan M,Obokata M,Koepp KE,Erwin P,Carter RE,Borlaug BA, 2019年08月, JACC. Heart failure, JACC. Heart failure, 7, 8, 678, 687
  • Characterization of the Obese Phenotype of Heart Failure With Preserved Ejection Fraction: A RELAX Trial Ancillary Study., Reddy YNV,Lewis GD,Shah SJ,Obokata M,Abou-Ezzedine OF,Fudim M,Sun JL,Chakraborty H,McNulty S,LeWinter MM,Mann DL,Stevenson LW,Redfield MM,Borlaug BA, 2019年07月, Mayo Clinic proceedings, Mayo Clinic proceedings, 94, 7, 1199, 1209
  • Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction: Understanding Mechanisms by Using Noninvasive Methods., Obokata M,Reddy YNV,Borlaug BA, 2020年01月, JACC. Cardiovascular imaging, JACC. Cardiovascular imaging, 13, 1 Pt 2, 245, 257
  • Myocardial Injury and Cardiac Reserve in Patients With Heart Failure and Preserved Ejection Fraction., Obokata M,Reddy YNV,Melenovsky V,Kane GC,Olson TP,Jarolim P,Borlaug BA, 2018年07月, Journal of the American College of Cardiology, Journal of the American College of Cardiology, 72, 1, 29, 40
  • Hemodynamic Correlates and Diagnostic Role of Cardiopulmonary Exercise Testing in Heart Failure With Preserved Ejection Fraction., Reddy YNV,Olson TP,Obokata M,Melenovsky V,Borlaug BA, 2018年08月, JACC. Heart failure, JACC. Heart failure, 6, 8, 665, 675
  • The Other Atrium in Heart Failure., Borlaug BA,Obokata M, 2019年08月, JACC. Cardiovascular imaging, JACC. Cardiovascular imaging, 12, 8 Pt 1, 1471, 1473
  • Left atrial dysfunction: the next key target in heart failure with preserved ejection fraction., Obokata M,Borlaug BA, 2019年04月, European journal of heart failure, European journal of heart failure, 21, 4, 506, 508
  • The Role of Echocardiography in Heart Failure with Preserved Ejection Fraction: What Do We Want from Imaging?, Obokata M,Reddy YNV,Borlaug BA, 2019年04月, Heart failure clinics, Heart failure clinics, 15, 2, 241, 256
  • Echocardiography-based pressure-volume loop assessment in the evaluation for the effects of indoxyl sulfate on cardiovascular function., Obokata M,Kurosawa K,Ishida H,Ito K,Ogawa T,Ando Y,Kurabayashi M,Negishi K, 2019年03月, Journal of echocardiography, Journal of echocardiography, 17, 1, 35, 43
  • Relationships of high cardiac output with ventricular morphology, myocardial energetics, and energy costs in hemodialysis patients with preserved ejection fraction., Harada T,Obokata M,Kurosawa K,Sorimachi H,Yoshida K,Ishida H,Ito K,Ogawa T,Ando Y,Kurabayashi M,Negishi K, 2019年03月, The international journal of cardiovascular imaging, The international journal of cardiovascular imaging, 35, 3, 469, 479
  • Deterioration in right ventricular structure and function over time in patients with heart failure and preserved ejection fraction., Obokata M,Reddy YNV,Melenovsky V,Pislaru S,Borlaug BA, 2019年02月, European heart journal, European heart journal, 40, 8, 689, 697
  • The β-Adrenergic Agonist Albuterol Improves Pulmonary Vascular Reserve in Heart Failure With Preserved Ejection Fraction., Reddy YNV,Obokata M,Koepp KE,Egbe AC,Wiley B,Borlaug BA, 2019年01月, Circulation research, Circulation research, 124, 2, 306, 314
  • Venous congestion and pulmonary vascular function in Fontan circulation: Implications for prognosis and treatment., Egbe AC,Reddy YNV,Khan AR,Al-Otaibi M,Akintoye E,Obokata M,Borlaug BA, 2018年11月, International journal of cardiology, International journal of cardiology, 271, 312, 316
  • Differences between first-generation and second-generation drug-eluting stent regarding in-stent neoatherosclerosis characteristics: an optical coherence tomography analysis., Kobayashi N,Ito Y,Yamawaki M,Araki M,Sakai T,Obokata M,Sakamoto Y,Mori S,Tsutsumi M,Nauchi M,Honda Y,Tokuda T,Makino K,Shirai S,Hirano K, 2018年10月, The international journal of cardiovascular imaging, The international journal of cardiovascular imaging, 34, 10, 1521, 1528
  • Early increase in serum fatty acid binding protein 4 levels in patients with acute myocardial infarction., Obokata M,Iso T,Ohyama Y,Sunaga H,Kawaguchi T,Matsui H,Iizuka T,Fukuda N,Takamatsu H,Koitabashi N,Funada R,Takama N,Kasama S,Kaneko Y,Yokoyama T,Murakami M,Kurabayashi M, 2018年09月, European heart journal. Acute cardiovascular care, European heart journal. Acute cardiovascular care, 7, 6, 561, 569
  • The strengths and limitations of E/e' in heart failure with preserved ejection fraction., Obokata M,Borlaug BA, 2018年09月, European journal of heart failure, European journal of heart failure, 20, 9, 1312, 1314
  • Left Atrial Contracture or Failure to Dilate., Obokata M,Reddy YNV,Yang JH,Wiley BM,Borlaug BA, 2018年09月, Circulation. Heart failure, Circulation. Heart failure, 11, 9, e005163
  • Haemodynamics, dyspnoea, and pulmonary reserve in heart failure with preserved ejection fraction., Obokata M,Olson TP,Reddy YNV,Melenovsky V,Kane GC,Borlaug BA, 2018年08月, European heart journal, European heart journal, 39, 30, 2810, 2821
  • A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction., Reddy YNV,Carter RE,Obokata M,Redfield MM,Borlaug BA, 2018年08月, Circulation, Circulation, 138, 9, 861, 870
  • Exercise unmasks distinct pathophysiologic features in heart failure with preserved ejection fraction and pulmonary vascular disease., Gorter TM,Obokata M,Reddy YNV,Melenovsky V,Borlaug BA, 2018年08月, European heart journal, European heart journal, 39, 30, 2825, 2835
  • Stress Imaging in Heart Failure: Physiologic, Diagnostic, and Therapeutic Insights., Obokata M,Borlaug BA, 2018年05月, Circulation. Cardiovascular imaging, Circulation. Cardiovascular imaging, 11, 5, e007785
  • Skeletal Muscle Compensation for Cardiac Muscle Insufficiency in Heart Failure and Reduced Ejection Fraction., Reddy YNV,Obokata M,Haykowsky MJ,Borlaug BA, 2018年01月, Circulation. Heart failure, Circulation. Heart failure, 11, 1, e004714
  • Response by Obokata and Borlaug to Letters Regarding Article, "Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction"., Obokata M,Borlaug BA, 2018年01月, Circulation, Circulation, 137, 4, 416, 417
  • High Prevalence of Occult Heart Failure With Preserved Ejection Fraction Among Patients With Atrial Fibrillation and Dyspnea., Reddy YNV,Obokata M,Gersh BJ,Borlaug BA, 2018年01月, Circulation, Circulation, 137, 5, 534, 535
  • [Left Atrial Strain Independently and Incrementally Predicts High Risk Thromboembolic Findings Over CHA2DS2-VASc Score and BNP]., Kurosawa K,Negishi K,Obokata M,Sorimachi H,Masuda K,Machida T,Kurabayashi M,Murakami M, 2017年02月, Rinsho byori. The Japanese journal of clinical pathology, Rinsho byori. The Japanese journal of clinical pathology, 65, 2, 138, 146
  • Massive pleural effusion due to pleural AA amyloidosis., Shimizu Y,Endou K,Hashizume Y,Kawata T,Horie T,Ogura H,Obokata M,Toyoda M,Ito H,Takise A, 2012年12月, American journal of respiratory and critical care medicine, American journal of respiratory and critical care medicine, 186, 12, e19, 20
  • [Case report; a case of refractory vasospastic angina with twice CPA event related to dysfunction of autonomic nervous system, which was successfully treated with thoracic sympathectomy]., Imai M,Obokata M,Ono Y,Kobayashi N,Kuribara J,Ui G,Tange S,Kamiyoshihara M, 2011年12月, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 100, 12, 3634, 3636
  • Multiple spontaneous coronary artery ruptures and cardiac tamponade in vascular Ehlers-Danlos syndrome., Ohyama Y,Iso T,Nino ACV,Obokata M,Takahashi R,Okumura W,Nakano A,Amano M,Naito I,Takatama M,Kurabayashi M, 2011年02月, Journal of cardiology cases, Journal of cardiology cases, 3, 1, e29, e32

MISC

  • Comparison of different interdialytic intervals among hemodialysis patients on their echocardiogram-based cardiovascular parameters, Masaru Obokata,Kazuaki Negishi,Thomas H. Marwick,Koji Kurosawa,Hideki Ishida,Kyoko Ito,Tetsuya Ogawa,Yoshitaka Ando,Masahiko Kurabayashi, 2015年04月, AMERICAN HEART JOURNAL, 169, 4, 523, +
  • A Risk Score with Additional Four Independent Factors to Predict the Incidence and Recovery from Metabolic Syndrome: Development and Validation in Large Japanese Cohorts, Masaru Obokata,Kazuaki Negishi,Yoshiaki Ohyama,Haruka Okada,Kunihiko Imai,Masahiko Kurabayashi, 2015年07月, PLOS ONE, 10, 7, e0133884
  • Indoxyl Sulfate, a Uremic Toxin, Contributes Pathogenesis of Uremic Cardiomyopathy through Reduction of Sarcoplasmic/endoplasmic Reticulum Calcium ATPase 2 Gene Expression, Masaru Obokata,Norimichi Koitabashi,Masahiko Kurabayashi, 2013年10月, JOURNAL OF CARDIAC FAILURE, 19, 10, S158, S158, 研究発表ペーパー・要旨(国際会議)
  • Cardiac Fibrosis Induced by Catecolamine is Paradoxically Controlled by Tgf-beta Signaling, Norimichi Koitabashi,Masaru Obokata,Masashi Arai,David A. Kass,Masahiko Kurabayashi, 2012年11月, CIRCULATION, 126, 21, 研究発表ペーパー・要旨(国際会議)
  • Catecholamine-induced Cardiac Fibrosis is Paradoxically Controlled by TGF beta Signaling, Norimichi Koitabashi,Masaru Obokata,Masashi Arai,David Kass,Masahiko Kurabayashi, 2012年10月, JOURNAL OF CARDIAC FAILURE, 18, 10, S189, S189, 研究発表ペーパー・要旨(国際会議)
  • Indoxyl Sulfate, a Uremic Toxin, Exaggerates Cardiac Growth Factor Expression, Masaru Obokata,Norimichi Koitabashi,Masashi Arai,Masahiko Kurabayashi, 2012年10月, JOURNAL OF CARDIAC FAILURE, 18, 10, S152, S152, 研究発表ペーパー・要旨(国際会議)
  • Vildagliptin Attenuates Cardiac Hypertrophy and Improves Ventricular Efficiency Through FGF21 Expression in Pressure-overloaded Mouse Heart, Nozomi Furukawa,Norimichi Koitabashi,Hiroaki Sunaga,Masaru Obokata,Yogi Umbarawan,Mas R. Syamsunarno,Aiko Yamaguchi,Hiroki Matsui,Tomoyuki Yokoyama,Masahiko Kurabayashi, 2016年11月, CIRCULATION, 134, 研究発表ペーパー・要旨(国際会議)
  • Direct comparison of cardiacmagnetic resonance feature tracking and 2D/3D echocardiography speckle tracking for evaluation of global left ventricular strain, Masaru Obokata,Yasufumi Nagata,Victor Chien-Chia Wu,Yuichiro Kado,Masahiko Kurabayashi,Yutaka Otsuji,Masaaki Takeuchi, 2016年05月, EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 17, 5, 525, 532
  • Independent and incremental prognostic value of novel cardiac biomarkers in chronic hemodialysis patients, Masaru Obokata,Hiroaki Sunaga,Hideki Ishida,Kyoko Ito,Tetsuya Ogawa,Yoshitaka Ando,Masahiko Kurabayashi,Kazuaki Negishi, 2016年09月, AMERICAN HEART JOURNAL, 179, 29, 41
  • 血中脂肪酸結合蛋白FABP4濃度は急性心筋梗塞および心停止患者で急激に上昇する, 小保方 優,大山 善昭,磯 達也,須永 浩章,倉林 正彦, 2015年09月, 日本心臓病学会学術集会抄録, 日本心臓病学会学術集会抄録, 63回, 872, 872
  • 新規心臓線維化バイオマーカーは維持透析患者の心血管イベントリスク層別化に有用である, 須永 浩章,小保方 優,根岸 一明,石田 秀岐,伊藤 恭子,小川 哲也,安藤 義孝,松井 弘樹,横山 知行,倉林 正彦, 2016年10月, 日本未病システム学会学術総会抄録集, 日本未病システム学会学術総会抄録集, 23回, 97, 97
  • ST2とgalectin-3の可溶性アイソフォームは、慢性血液透析患者における独立的かつ追加的な予後予測能を有する(Soluble Isoforms of ST2 and Galectin-3 Have Independent and Incremental Prognostic Value in Chronic Hemodialysis Patients), 須永 浩章,小保方 優,小川 哲也,根岸 一明,倉林 正彦, 2017年03月, 日本循環器学会学術集会抄録集, 日本循環器学会学術集会抄録集, 81回, PJ, 057
  • 血液透析患者における臨床転帰悪化を示す新規バイオマーカーとしての血中ケトン体(Circulating Ketone Body as a Novel Biomarker for Worse Clinical Outcomes in Hemodialysis Patients), 須永 浩章,小保方 優,根岸 一明,小川 哲也,磯 達也,小板橋 紀通,倉林 正彦, 2018年03月, 日本循環器学会学術集会抄録集, 日本循環器学会学術集会抄録集, 82回, OJ03, 1
  • Vildagliptin Attenuates Cardiac Hypertrophy and Improves Ventricular Efficiency Through FGF21 Expression in Pressure-overloaded Mouse Heart, Nozomi Furukawa,Norimichi Koitabashi,Hiroaki Sunaga,Masaru Obokata,Yogi Umbarawan,Mas R. Syamsunarno,Aiko Yamaguchi,Hiroki Matsui,Tomoyuki Yokoyama,Masahiko Kurabayashi, 2016年11月, CIRCULATION, 134, 研究発表ペーパー・要旨(国際会議)
  • A Massive Increase in Serum Levels of Fatty Acid Binding Protein 4 in Patients With Acute Myocardial Infarction Complicated by Out-of-Hospital Cardiac Arrest Due to Ventricular Fibrillation, Hiroaki Sunaga,Tatsuya Iso,Masaru Obokata,Yoshiaki Ohyama,Norimichi Koitabashi,Ryuichi Funada,Noriaki Takama,Hiroki Matsui,Tomoyuki Yokoyama,Masami Murakami,Masahiko Kurabayashi, 2016年11月, CIRCULATION, 134, 研究発表ペーパー・要旨(国際会議)
  • Integrated Area of Desaturation Index can Predict Three-Year Prognosis in Heart Failure Patients after Adaptive Servo Ventilation Therapy, Noriaki Takama,Hiroshi Hasegawa,Keita Goto,Kuniko Masuda,Hidemi Sorimachi,Makito Sato,Masaru Obokata,Yae Matsuo,Hirokazu Sano,Ryuichi Funada,Syu Kasama,Norimichi Koitabashi,Masahiko Kurabayashi, 2014年11月, CIRCULATION, 130, 研究発表ペーパー・要旨(国際会議)
  • Early Increase in Serum Fatty Acid Binding Protein 4 Levels in Patients with Acute Myocardial Infarction: Lipolysis as a Novel Marker for Myocardial Ischemia, Hiroaki Sunaga,Yoshiaki Ohyama,Masaru Obokata,Tatsuya So,Tomoka Kawaguchi,Norimichi Koitabashi,Ryuichi Funada,Noriaki Takama,Mas Rizky A. Syamsunarno,Hiroki Matsui,Tomoyuki Yokoyama,Masahiko Kurabayashi, 2014年11月, CIRCULATION, 130, 研究発表ペーパー・要旨(国際会議)
  • 脂肪酸結合タンパクFABP4は急性心筋梗塞の早期診断マーカーとして有用である, 須永 浩章,磯 達也,大山 善昭,小保方 優,河口 智香,小板橋 紀通,Syamsunarno MasRizky A.A,松井 弘樹,横山 知行,倉林 正彦, 2015年09月, 日本未病システム学会学術総会抄録集, 日本未病システム学会学術総会抄録集, 22回, 136, 136
  • Relation Between Echocardiogram-Based Cardiac Parameters and Outcome in Heart Failure With Preserved and Reduced Ejection Fraction, Masaru Obokata,Masaaki Takeuchi,Kazuaki Negishi,Nobuyuki Ohte,Masaki Izumo,Eiji Yamashita,Mio Ebato,Satoshi Yuda,Masahiko Kurabayashi,Satoshi Nakatani, 2016年11月, AMERICAN JOURNAL OF CARDIOLOGY, 118, 9, 1356, 1362
  • Cumulative Burden of Myocardial Dysfunction in Cardiac Amyloidosis Assessed Using Four-Chamber Cardiac Strain, Yuichiro Kado,Masaru Obokata,Yasufumi Nagata,Tomoko Ishizu,Karima Addetia,Kazutaka Aonuma,Masahiko Kurabayashi,Roberto M. Lang,Masaaki Takeuchi,Yutaka Otsuji, 2016年11月, JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 29, 11, 1092, +
  • Effect of Sex Differences on the Association Between Stroke Risk and Left Atrial Anatomy or Mechanics in Patients With Atrial Fibrillation, Kuniko Yoshida,Masaru Obokata,Koji Kurosawa,Hidemi Sorimachi,Masahiko Kurabayashi,Kazuaki Negishi, 2016年10月, CIRCULATION-CARDIOVASCULAR IMAGING, 9, 10, e004999
  • Left Atrial Strain Provides Incremental Value for Embolism Risk Stratification over CHA(2)DS(2)-VASc Score and Indicates Prognostic Impact in Patients with Atrial Fibrillation, Masaru Obokata,Kazuaki Negishi,Koji Kurosawa,Rieko Tateno,Shoichi Tange,Masashi Arai,Masao Amano,Masahiko Kurabayashi, 2014年07月, JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 27, 7, 709, U70
  • Fatty Acid Binding Protein 4 and 5 Play a Crucial Role in Thermogenesis under the Conditions of Fasting and Cold Stress, Mas Rizky A. A. Syamsunarno,Tatsuya Iso,Aiko Yamaguchi,Hirofumi Hanaoka,Mirasari Putri,Masaru Obokata,Hiroaki Sunaga,Norimichi Koitabashi,Hiroki Matsui,Kazuhisa Maeda,Keigo Endo,Yoshito Tsushima,Tomoyuki Yokoyama,Masahiko Kurabayashi, 2014年03月, PLOS ONE, 9, 3, e90825
  • Incremental Prognostic Value of Ventricular-Arterial Coupling over Ejection Fraction in Patients with Maintenance Hemodialysis, Masaru Obokata,Koji Kurosawa,Hideki Ishida,Kyoko Ito,Tetsuya Ogawa,Yoshitaka Ando,Masahiko Kurabayashi,Kazuaki Negishi, 2017年05月, JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 30, 5, 444, +
  • Ventricular-Arterial Coupling and Exercise-Induced Pulmonary Hypertension During Low-Level Exercise in Heart Failure With Preserved or Reduced Ejection Fraction, Masaru Obokata,Yasufumi Nagata,Yuichiro Kado,Masahiko Kurabayashi,Yutaka Otsuji,Masaaki Takeuchi, 2017年03月, JOURNAL OF CARDIAC FAILURE, 23, 3, 216, 220
  • Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice, Yogi Umbarawan,Mas Rizky A. A. Syamsunarno,Hideru Obinata,Aiko Yamaguchi,Hiroaki Sunaga,Hiroki Matsui,Takako Hishiki,Tomomi Matsuura,Norimichi Koitabashi,Masaru Obokata,Hirofumi Hanaoka,Anwarul Haque,Fumio Kunimotol,Yoshito Tsushima,Makoto Suematsu,Masahiko Kurabayashi,Tatsuya Iso, 2017年12月, METABOLISM-CLINICAL AND EXPERIMENTAL, 77, 47, 57
  • A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting, Syamsunarno,Mas Rizky A. A,Iso\, Tatsuya,Hanaoka\, Hirofumi,Yamaguchi\, Aiko,Obokata\, Masaru,Koitabashi\, Norimichi,Goto\, Kosaku,Hishiki\, Takako,Nagahata\, Yoshiko,Matsui\, Hiroki,Sano\, Motoaki,Kobayashi\, Masaki,Kikuchi\, Osamu,Sasaki\, Tsutomu,Maeda\, Kazuhisa,Murakami\, Masami,Kitamura\, Tadahiro,Suematsu\, Makoto,Tsushima\, Yoshito,Endo\, Keigo,Hotamisligil,Goekhan S,Kurabayashi\, Masahiko, 2013年, PLOS ONE, 8, 11, e79386
  • Incremental Diagnostic Value of LA Strain With Leg Lifts in Heart Failure With Preserved Ejection Fraction, Obokata\, Masaru,Negishi\, Kazuaki,Kurosawa\, Koji,Arima\, Hitomi,Tateno\, Rieko,Ui\, Goro,Tange\, Shoichi,Arai\, Masashi,Kurabayashi\, Masahiko, 2013年, JACC-CARDIOVASCULAR IMAGING, 6, 7, 749, 758
  • Association Between Circulating Ketone Bodies and Worse Outcomes in Hemodialysis Patients, Obokata\, Masaru,Negishi\, Kazuaki,Sunaga\, Hiroaki,Ishida\, Hideki,Ito\, Kyoko,Ogawa\, Tetsuya,Iso\, Tatsuya,Ando\, Yoshitaka,Kurabayashi\, Masahiko, 2017年, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 6, 10, e006885

受賞

  • 公募研究助成, Research grant, 小保方優, Masaru Obokata, 日本新薬, Nippon Shinyaku, 2020年02月
  • 2019 年度日本循環器学会 医師臨床研究助成, Research Grant for Clinical Investigation, 小保方 優, Obokata Masaru, 日本循環器学会, The Japanese Circulation Society, 2020年02月
  • Young Investigator’s Award優秀賞, Young Investigator’s Award, 小保方 優, Obokata Masaru, 日本心エコー図学会, Japanese Society of Echocardiography, 2012年04月
  • Young Investigator’s Award優秀賞, Young Investigator’s Award, 小保方 優, Obokata Masaru, 日本心臓病学会, Japanese Collage of Cardiology, 2014年09月
  • 海外学会発表優秀論文賞, Abstract Award for Overseas Congress, 小保方 優, Obokata Masaru, 日本心エコー図学会, Japanese Society of Echocardiography, 2015年01月
  • Echo U-40-Research Achievement Award, Echo U-40-Research Achievement Award, 小保方 優, Obokata Masaru, 日本心エコー図学会, Japanese Society of Echocardiography, 2015年03月
  • Young Investigator’s Award優秀賞, Young Investigator’s Award, 小保方 優, Obokata Masaru, 日本循環器学会, Japanese Circulation Society, 2015年04月
  • Banyu Fellowship Program生活習慣病領域, Banyu Fellowship Program, 小保方 優, Obokata Masaru, MSD生命科学財団, MSD life Science Foundation, 2015年12月
  • 海外留学助成, Research Grant, 小保方 優, Obokata Masaru, 日本心エコー図学会, Japanese Society of Echocardiography, 2017年06月
  • トラベルグラント賞, Travel Grant Awards, 小保方 優, Obokata Masaru, アメリカ心不全学会, Heart Failure Society of America (HFSA), 2017年09月
  • 海外留学助成リサーチフェローシップ, Research fellowship, 小保方 優, Obokata Masaru, 上原記念生命科学財団, The Uehara Memorial Foundation, 2017年12月
  • 第5回循環器イメージング賞優秀賞, 5th Cardiovascualr Imaging Award, 小保方 優, Obokata Masaru, 日本循環器学会, Japanese Circulation Society, 2018年03月
  • 研究助成, Research grant, 小保方 優, Obokata Masaru, 福田記念医療技術振興財団, Fukuda Foundation for Medical Technology, 2019年06月
  • Jay N. Cohn New Investigator Award, Jay N. Cohn New Investigator Award, 小保方 優, Obokata Masaru, アメリカ心不全学会, Heart Failure Society of America (HFSA), 2018年09月
  • 研究助成, Research grant, 小保方 優, Obokata Masaru, 持田記念医学薬学振興財団, Mochida Memorial Foundation for Medical and Pharmaceutical Research, 2019年09月


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