Researcher Profile and Settings

Researcher

• Name

  MAEJIMA Ikuko

Profile and Settings

• Name

  MAEJIMA, Ikuko

Alternate Names

• Ikuko MAEJIMA

Education

• Apr. 2008, Mar. 2013
• Apr. 2001, Mar. 2007

Association Memberships

• The Japanese Biochemical Society, 2011, 9999
• The Molecular Biology Society of Japan, 2009, 9999
• Japan Society for Cell Biology, 2021, 9999

Research Experience

• Apr. 2021, 9999
• Apr. 2019, Mar. 2021
• Apr. 2016, Mar. 2019
• Apr. 2014, Mar. 2016
• Apr. 2013, Mar. 2014, Osaka University

Research Activities

Research Areas

• Life sciences, Cell biology
• Life sciences, Molecular biology
• Life Science, Neuroscience

Published Papers

• New aspects of a small GTPase RAB35 in brain development and function, Maejima, Ikuko; Sato, Ken, Jul. 2025, Neural Rregeneration Research, 20, 7, 1971, 1980, Scientific journal

  DOI
• Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking., Yamasaki Akinori;Hara Taichi;Maejima Ikuko;Sato Miyuki;Sato Katsuya;Sato Ken, Aug. 2014, Scientific reports, 4

  DOI
• Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules., Takahashi Atsushi;Takabatake Yoshitsugu;Kimura Tomonori;Maejima Ikuko;Namba Tomoko;Yamamoto Takeshi;Matsuda Jun;Minami Satoshi;Kaimori Jun-Ya;Matsui Isao;Matsusaka Taiji;Niimura Fumio;Yoshimori Tamotsu;Isaka Yoshitaka, Feb. 2017, Diabetes, 66, 5

  DOI
• Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development., Hara Taichi;Maejima Ikuko;Akuzawa Tomoko;Hirai Rika;Kobayashi Hisae;Tsukamoto Satoshi;Tsunoda Mika;Ono Aguri;Yamakoshi Shota;Oikawa Satoshi;Sato Ken, Sep. 2018, PLoS genetics, 14, 9

  DOI
• Autophagy-targeted therapy to modulate age-related diseases: Success, pitfalls, and new directions., Martins Waleska Kerllen;Silva Maryana do Nascimento da;Pandey Kiran;Maejima Ikuko;Ramalho Ercilia;Olivon Vania Claudia;Diniz Susana Nogueira;Grasso Daniel, Jun. 2021, Current research in pharmacology and drug discovery, 2

  DOI
• Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages., Matsunaga Kohichi;Saitoh Tatsuya;Tabata Keisuke;Omori Hiroko;Satoh Takashi;Kurotori Naoki;Maejima Ikuko;Shirahama-Noda Kanae;Ichimura Tohru;Isobe Toshiaki;Akira Shizuo;Noda Takeshi;Yoshimori Tamotsu, Mar. 2009, Nature cell biology, 11, 4

  DOI
• Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury., Maejima Ikuko;Takahashi Atsushi;Omori Hiroko;Kimura Tomonori;Takabatake Yoshitsugu;Saitoh Tatsuya;Yamamoto Akitsugu;Hamasaki Maho;Noda Takeshi;Isaka Yoshitaka;Yoshimori Tamotsu, Aug. 2013, The EMBO journal, 32, 17

  DOI
• Selective autophagy: lysophagy., Hasegawa Junya;Maejima Ikuko;Iwamoto Ryo;Yoshimori Tamotsu, Dec. 2014, Methods (San Diego, Calif.), 75

  DOI
• RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution., Maejima Ikuko;Hara Taichi;Tsukamoto Satoshi;Koizumi Hiroyuki;Kawauchi Takeshi;Akuzawa Tomoko;Hirai Rika;Kobayashi Hisae;Isobe Inoya;Emoto Kazuo;Kosako Hidetaka;Sato Ken, Apr. 2023, Communications biology, 6, 1

  DOI
• RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution, Maejima, Ikuko;Hara, Taichi;Tsukamoto, Satoshi;Koizumi, Hiroyuki;Kawauchi, Takeshi;Akuzawa, Tomoko;Hirai, Rika;Kobayashi, Hisae;Isobe, Inoya;Emoto, Kazuo;Kosako, Hidetaka;Sato, Ken, 2023, COMMUNICATIONS BIOLOGY, 6, 1

  DOI
• 細胞内輸送関連因子による成体脳神経新生機構の解明, ;;, Nov. 2024, 97回, [2P

MISC

• Autophagy-targeted therapy to modulate age-related diseases: Success, pitfalls, and new directions, Waleska Kerllen Martins, Maryana do Nascimento da Silva, Kiran Pandey, Ikuko Maejima, Ercilia Ramalho, Vania Claudia Olivon, Susana Nogueira Diniz, Daniel Grasso, 2021, Current Research in Pharmacology and Drug Discovery, 2, 100033, 100033

  DOI
• Lysophagy: Novel selective autophagy eliminating damanged oraganelles and suppressing diseases, M. Hamasaki; H. Teranishi; I. Maejima; T. Yoshimori, 2015, MOLECULAR BIOLOGY OF THE CELL, 26, Summary international conference
• 広がるオートファジーの世界 オートファジーによる細胞内侵入性細菌の認識機構, 前島 郁子; 吉森 保, Oct. 2014, 化学と生物, 52, 10, 680, 684
• 腎症を抑制するリソファジーとがん細胞オートファジーの解析, 濱崎万穂; 前島郁子; 吉森保, 2014, 日本生化学会大会(Web), 87th, WEB ONLY 2S07P-4

Presentations

• 低分子量GTPase Rab35の神経発生における機能解析, 前島郁子; 原太一; 塚本智史; 古泉博之; 川内健史; 阿久澤共子; 平井里香; 小林久江; 磯部いの八; 榎本和生; 小迫英尊; 佐藤 健, 第43回日本分子生物学会, Online, Dec. 2020
• オートファジーによる損傷リソソームの排除, 前島郁子; 高橋篤史; 大森弘子; 木村友則; 高畠義嗣; 齋藤達哉; 山本章嗣; 濱崎万穂; 野田健司; 猪阪善隆; 吉森保, 第66回日本細胞生物学会大会, 奈良, Jun. 2014
• オートファジーによる損傷リソソームの除去は細胞の恒常性維持に必要である, 前島郁子; 高橋篤史; 大森弘子; 木村友則; 高畠義嗣; 齋藤達哉; 山本章嗣; 濱崎万穂; 野田健司; 猪阪善隆; 吉森保, 第65回日本細胞生物学会大会, 名古屋, Jun. 2013
• Autophagy is involved in turnover of damaged lysosomes, Ikuko Maejima; Hiroko Omori; Takeshi Noda; Tamotsu Yoshimori, The Gordon Research Conference on Autopahgy in Stress, Development & Disease, Venture, CA, USA, Mar. 2012
• Autophagy is involved in turnover of damaged lysosomes, 前島郁子; 野田健司; 吉森保, 第84回日本生化学会大会, 京都, Sep. 2011

Awards

• Jan. 2011

Research Projects

• Japan Society for the Promotion of Science, 01 Apr. 2023, 31 Mar. 2026, Principal investigator
• Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows, Grant-in-Aid for JSPS Fellows, Gunma University, Apr. 2019, Mar. 2022, 19J40272
• Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows, Grant-in-Aid for JSPS Fellows, Gunma University, Apr. 2016, Mar. 2019, 16J11714

Social Contribution

Social Contribution

• 高校生のための最先端生命科学＆重粒子線医学セミナー, 16 Mar. 2024, 16 Mar. 2024　(Target:　High school students)
• オープンラボ　Aコース, 04 Aug. 2023, 04 Aug. 2023　(Target:　High school students)
• 第8回生体調節研究所内分泌・代謝シンポジウム, 10 Nov. 2022, 11 Nov. 2022
• 附置研究所・センター会議二部会シンポジウム, 25 Nov. 2022, 25 Nov. 2022
• 「博士のキャリアをどう作る？経験者からのリアルな情報収集、ここでできます」, 30 Jun. 2022, 30 Jun. 2022　(Target:　College students, Graduate students, Teachers, Researchers, General)
• 2022年度群馬ちびっ子大学「とっても役立つ光る生物の秘密」, 02 Aug. 2022, 22 Aug. 2022　(Target:　Schoolchildren, Junior high school students, High school students, College students, Graduate students, Teachers, Guardians, General)
• まちなかキャンパス, Apr. 2021, Mar. 2021　(Target:　General)